Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [listeria monocytogenes femoral aneurysm]. | secondary infection of arterial aneurysms being a constantly possible complication, the bacteriological examination of peroperative specimens appears to be appropriate. among responsible organisms, the presence of listeria monocytogenes is very rare since only 13 cases have been reported in the literature. it is for this reason that it was felt to be of interest to report a new, entirely similar case of femoral aneurysm. | 1993 | 8517597 |
| detection of a prfa-independent promoter responsible for listeriolysin gene expression in mutant listeria monocytogenes strains lacking the prfa regulator. | expression of listeriolysin, a major virulence factor of pathogenic listeria monocytogenes, is positively regulated by the pleiotropic virulence regulator prfa. in this study, we demonstrate that l. monocytogenes strains lacking the prfa regulator gene produce listeriolysin in small, albeit detectable, amounts when analyzed in a hemolysin assay and by immunoblots with listeriolysin-specific monoclonal antibodies. transcriptional analysis revealed the existence of a prfa-independent promoter that ... | 1993 | 8514414 |
| multiplication of listeria monocytogenes in a murine hepatocyte cell line. | listeria monocytogenes was shown to invade and multiply in a murine hepatocyte cell line (atcc tib73). hemolytic and nonhemolytic l. monocytogenes strains exhibited similar abilities to invade hepatocytes, but only hemolytic l. monocytogenes multiplied within this cell line. microscopic evaluation of monolayers stained with wright stain demonstrated focal necrosis (plaques) in the hepatocyte monolayers, with large numbers of intracellular listeriae visible within the hepatocytes that lined the m ... | 1993 | 8514413 |
| antimicrobial proteins of murine macrophages. | three murine microbicidal proteins (mumps) were purified from cells of the murine macrophage cell line raw264.7 that had been activated by gamma interferon. similar proteins were also present in nonactivated raw264.7 cells, in cells of the murine macrophage cell line j774a.1, and in resident and activated murine peritoneal macrophages. mump-1, mump-2, and mump-3 killed salmonella typhimurium, escherichia coli, staphylococcus aureus, listeria monocytogenes, mycobacterium fortuitum, and cryptococc ... | 1993 | 8514411 |
| localization of the acta polypeptide of listeria monocytogenes in infected tissue culture cell lines: acta is not associated with actin "comets". | the acta protein of the gram-positive pathogen listeria monocytogenes is a 90-kda polypeptide required for interaction of the bacteria with components of the host cell microfilament system to generate intra- and intercellular movement. to study the localization, distribution, and expression of the acta polypeptide in l. monocytogenes grown either in broth culture or in infected tissue culture cells, we first isolated acta by monoclonal antibody-based immunoaffinity chromatography. polyclonal rab ... | 1993 | 8514381 |
| an anti-cd3 monoclonal antibody protects mice against a lethal infection with listeria monocytogenes through induction of endogenous cytokines. | mice were protected against a lethal infection with listeria monocytogenes when treated with low doses of an anti-cd3 monoclonal antibody (mab). injection of anti-cd3 mab induced rapid production of endogenous tumor necrosis factor (tnf) in the spleens and endogenous gamma interferon (ifn-gamma) in the bloodstreams and spleens of mice. administration of anti-thy1.2 mab or a combination of anti-cd4 mab and anti-cd8 mab resulted in suppression of anti-cd3 mab-induced endogenous cytokine production ... | 1993 | 8514380 |
| utilization of transferrin-bound iron by listeria monocytogenes. | it has been demonstrated that under iron-restricted conditions, listeria monocytogenes can utilize iron-loaded transferrin (tf) from a range of species as its sole source of iron for growth. human transferrin conjugated to horseradish-peroxidase (hrp-tf) bound directly to whole cells of l. monocytogenes. this binding was blocked by apotransferrin indicating that the receptor can bind transferrin in either the iron-bound or iron-free form. transferrin-binding was not host specific because both bo ... | 1993 | 8514118 |
| [liver abscess revealing listeriosis]. | 1993 | 8511072 | |
| listeria monocytogenes infections: the organism, its pathogenicity and antimicrobial drugs susceptibility. | l. monocytogenes can induce serious, life-threatening infections. multiple clinical manifestations of the disease include neonatal and perinatal listeriosis, infections in adult immunocompromised patients as well as in normal hosts, with the cns as the more frequent site involved. many outbreaks are believed to be food-borne in origin, but there can be other means of transmission. the susceptibility of l. monocytogenes to different antimicrobial drugs is reviewed. many drugs that are highly effe ... | 1993 | 8510575 |
| murine complement receptor gene expression: cr2 gene transcripts are depressed during a high dose microbial challenge. | the murine cr2 gene encodes mrna that produce two protein products predicted to be approximately 145,000 m(r) (cr2-145) and 190,000 m(r) (cr2-190). all cells examined which express the cr2 gene produce transcripts encoding both the cr2-145 and cr2-190 proteins: both transcripts are constitutively expressed by mature b cells. to determine if cr2 expression could be altered by activating splenic b cells, splenic cultures were incubated with lipopolysaccharide (lps) and cell surface ig chains were ... | 1993 | 8509145 |
| characterization of listeria strains from a foodborne listeriosis outbreak by rdna gene restriction patterns compared to four other typing methods. | the rdna gene restriction patterns of 134 isolates of listeria species were determined with pkk3535--a pbr322 derived plasmid containing an escherichia coli rrna operon--used as a probe following digestion of chromosomal dna by ecori endonuclease. nineteen reference and type strains representing all species and serotypes of listeria showed 17 distinct ribotypes. one hundred and fifteen wild strains of listeria monocytogenes were ribotyped and the results were compared to those of serotyping, pha ... | 1993 | 8508814 |
| incidence of listeriosis in barcelona, spain, in 1990. the collaborative study group of listeriosis of barcelona. | a population-based register of cases of listeriosis admitted to acute-care hospitals has been established in barcelona, spain, in order to estimate the basal incidence of sporadic cases and to facilitate epidemiological surveillance of potential epidemics. eleven acute-care hospitals reported all cases of listeriosis to a central unit following a standardized protocol. during 1990, 31 patients with listeriosis were identified, 18 of whom were residents of the city, resulting in an annual inciden ... | 1993 | 8508813 |
| brainstem encephalitis (rhombencephalitis) due to listeria monocytogenes: case report and review. | listerial brainstem encephalitis is a rare disease. only 62 cases have been reported previously; all were in adults, only 8% of whom were immunosuppressed. the disease has a characteristic biphasic course: a nonspecific prodrome of headache, nausea or vomiting, and fever lasting for several days is followed by progressive asymmetrical cranial-nerve palsies, cerebellar signs, hemiparesis or hypesthesia, and impairment of consciousness. neck stiffness was initially present in only 55% of the cases ... | 1993 | 8507761 |
| effect of legionella pneumophila sonicate on killing of listeria monocytogenes by human polymorphonuclear neutrophils and monocytes. | legionella pneumophila shares with other intracellular pathogens the ability to resist intracellular killing within phagocytes. an increasing number of cellular components of l. pneumophila are proposed as pathogenic factors of the organism. at the site of infection, the phagocytic cells will be exposed to bacterial components, either expressed on the surface of the organisms or released in the environment upon cell lysis. in this study, we have investigated the effect of water-soluble bacterial ... | 1993 | 8507462 |
| neonatal cross-infection with listeria monocytogenes. | transmission of listeria monocytogenes by food continues to cause concern. even so, this is not the only means of transmission and neonatal hospital-acquired infection has been well recorded. we report here two cases of perinatal listeriosis one of which was likely to have been due to cross-contamination in a special care baby unit (scbu) with equipment acting as the vehicle. | 1993 | 8505564 |
| [listeria monocytogenes in patients with human immunodeficiency virus infection. 2 cases]. | 1993 | 8502634 | |
| cytokine mrna expression in livers of mice infected with listeria monocytogenes. | temporally distinct groups of cytokine expression was observed by reverse transcription-polymerase chain reaction assay, in situ hybridization, and immunohistochemistry in the livers of listeria monocytogenes-infected mice. one group consisted of interferon-gamma (ifn-gamma), tumor necrosis factor alpha (tnf-alpha), and interleukin-10 (il-10), for which mrnas were induced within 1 day after challenge. a second group consisted of il-2 and il-4, for which mrna was strongly expressed at 1 day but t ... | 1993 | 8501395 |
| listeria monocytogenes-induced interferon-gamma primes the host for production of tumor necrosis factor and interferon-alpha/beta. | mice acquired an enhanced capacity for the production of tumor necrosis factor (tnf) and the interferons (ifn)-alpha, and -beta shortly after intravenous injection of viable listeria monocytogenes. by the end of the first day of a sublethal infection, mice were primed to produce 100-1000 times more endotoxin-induced serum tnf than is produced by normal mice. acquisition of the augmented capacity for tnf production was due to l. monocytogenes-induced ifn-gamma. ifn-gamma also primed infected mice ... | 1993 | 8501325 |
| the cellular source of interleukin-6 during listeria infection. | the cellular source of interleukin-6 (il-6) during infection of mice with listeria monocytogenes was investigated both in vitro and in vivo. peritoneal cells taken at intervals from infected mice and cultured in vitro without added stimulus produced high titers of il-6 peaking 2 days postinfection in a time course similar to that observed in vivo. adherent cells with the morphology of macrophages were a major source of this il-6. spleen cells similarly harvested at intervals and cultured with he ... | 1993 | 8500900 |
| effects of listeria monocytogenes and yersinia enterocolitica on cytokine gene expression and release from human polymorphonuclear granulocytes and epithelial (hep-2) cells. | the gene expression and cytokine release of the proinflammatory cytokines interleukin-1 beta (il-1 beta), il-6, and tumor necrosis factor alpha (tnf-alpha) after infection of human epithelial cells (hep-2 cells) and polymorphonuclear granulocytes (pmns) were investigated by using isogenic pairs of listeria monocytogenes and yersinia enterocolitica strains. by polymerase chain reaction-assisted mrna amplification and rna dot blot analysis, we showed that pmns and hep-2 cells expressed enhanced le ... | 1993 | 8500890 |
| pulsed-field gel electrophoresis applied for comparing listeria monocytogenes strains involved in outbreaks. | recent food-borne outbreaks of human listeriosis as well as numerous sporadic cases have been mainly caused by listeria monocytogenes serovar 4b strains. thus, it was of interest to find out whether a certain clone or a certain few clones were responsible for these cases and especially for outbreaks. we used pulsed-field gel electrophoresis of large chromosomal dna restriction fragments generated by apai, smai, or noti to analyse 75 l. monocytogenes strains isolated during six major and eight sm ... | 1993 | 8500010 |
| arsenic in the sera of gallium arsenide-exposed mice inhibits bacterial growth and increases host resistance. | the objective of the present investigations was to evaluate whether the presence of gallium arsenide (gaas) in the sera of exposed mice was sufficient to retard bacterial growth. host resistance studies demonstrated that exposure of gaas (50-200 mg/kg) produced an increased resistance to streptococcus pneumoniae and listeria monocytogenes (50-100 mg/kg gaas) when microbial challenge occurred 24 hr after exposure. in contrast, exposed mice exhibited a profound and dose-related decrease in resista ... | 1993 | 8496824 |
| early symptoms and outcome of listeria monocytogenes rhombencephalitis: 14 adult cases. | listeria monocytogenes rhombencephalitis has never been studied in a significant group of patients. we describe 14 adult cases who were seen over a 10-year period. a biphasic illness was characteristic: (1) prodromes (5-15 days) with malaise, fatigue, headache, nausea or vomiting, and fever; (2) cranial nerve palsy with facial palsy, diplopia, dysphagia, dysarthria, usually multiple. meningism and hemi- or tetraparesis were present in 11 patients and cerebellar dysfunction in 9 patients. in 4 ca ... | 1993 | 8496712 |
| pathogen-induced th1 phenotype development in cd4+ alpha beta-tcr transgenic t cells is macrophage dependent. | we used an ovalbumin (ova)-specific alpha beta-tcr transgenic mouse system to examine the cellular basis of cd4+ t helper (th) phenotype development in vitro. heat-killed listeria monocytogenes (hklm) strongly promotes the in vitro development of a th1 phenotype in ova-specific transgenic t cells. listeria monocytogenes effects to promote the th1 phenotype are antigen presenting cell (apc) dependent and occur when splenic apcs, but not the b cell hybridoma ta3, are present during t cell activati ... | 1993 | 8494824 |
| fate of listeria monocytogenes in raw and cooked ground beef with meat processing additives. | the effect of sodium lactate (1.8% w/w), sodium erythorbate (0.1% w/w), kappa-carrageenan (1% w/w), and the alginate meat binder (0.4% w/w, sodium alginate; 0.6% w/w lactic acid; and 0.075% w/w calcium carbonate) on listeria monocytogenes survival and growth was determined in raw and cooked ground beef stored aerobically at 4 degrees c. there was no significant (p > 0.05) increase in numbers of l. monocytogenes during storage of raw ground beef. however, l. monocytogenes numbers were generally l ... | 1993 | 8494691 |
| five-tube most-probable-number method using the fung-yu tube for enumeration of listeria monocytogenes in restructured meat products during refrigerated storage. | the survival of listeria monocytogenes in cooked, chopped hams stored at 5 degrees c for 5 weeks was studied. slices of chopped ham (25 g) were inoculated with a three-strain mixture of l. monocytogenes (lm 101m, lm 103m, and scott a) at levels of < or = 350 cfu/25 g and packaged in stomacher bags. prior to inoculation, l. monocytogenes cells were subjected to either heat-injury (56 degrees c, 30 min) or freeze-injury (-18 degrees c, 14 days). the organisms were detected by a five-tube most-prob ... | 1993 | 8494686 |
| characterization of listeria strains isolated from soft cheese. | three soft cheeses were exposed to quantitative analysis for listeria and found to contain a large number of listeria. thirty-five of the listeria strains isolated from the three cheeses were characterized by use of biochemical tests, serotyping, phagetyping and dna restriction enzyme analysis. seven isolates were identified as listeria innocua and 28 as listeria monocytogenes. two to four different clones of l. monocytogenes could be identified from each cheese. in contrast, only one clone coul ... | 1993 | 8494682 |
| modelling bacterial growth of listeria monocytogenes as a function of water activity, ph and temperature. | temperature, ph and water activity are important factors controlling the microbiological safety of foods. to describe the growth rate of listeria monocytogenes in relation to these factors, two equations have been developed. both equations are based upon the ratkowsky equation for temperature and growth rate. the first equation predicts growth rate at sub-optimal ph values, sub-optimal temperatures and sub-optimal water activities, the second model predicts growth throughout the entire ph range. ... | 1993 | 8494680 |
| antilisterial activity of pediocin ach in model food systems in the presence of an emulsifier or encapsulated within liposomes. | the listericidal activity of pediocin ach was evaluated in slurries (5, 10, or 25% in dh2o) of nonfat dry milk, butterfat, beef muscle tissue, or beef tallow. slurries were inoculated with listeria monocytogenes (2-strain mixture; 2.5 x 10(6) cfu/ml) and then with pediocin ach (30,000 arbitrary units (au) per ml of slurry). although pediocin activity was reduced in slurries, sufficient pediocin remained to decrease the listeriae population. for all slurries tested, the greatest decrease in count ... | 1993 | 8494679 |
| [double listeria monocytogenes and leptospira infection]. | 1993 | 8493235 | |
| membrane permeabilization of listeria monocytogenes and mitochondria by the bacteriocin mesentericin y105. | mesentericin y105, a bacteriocin produced by a leuconostoc mesenteroides strain, dissipates the plasma membrane potential of listeria monocytogenes and inhibits the transport of leucine and glutamic acid. it also induces an efflux of preaccumulated amino acids from cells. in addition, the bacteriocin uncouples mitochondria by increasing state 4 respiration and decreasing state 3 respiration. the bacteriocin inhibits atp synthase and adenine nucleotide translocase of the organelle while the affin ... | 1993 | 8491741 |
| listeria monocytogenes infection of a prosthetic vascular graft. | a 75-year-old man was admitted for acute ischaemia of his right leg for which he had undergone vascular prosthetic surgery at another hospital, ten and three years before. cultures of the thrombosed graft and the clots removed on re-operation were positive for listeria monocytogenes. after parenteral treatment with amoxicillin-clavulanic acid and gentamicin, the patient died from cardiorespiratory failure. | 1993 | 8491522 |
| a new danish listeria monocytogenes phage typing system. | a phage typing system was developed for listeria monocytogenes. phages were released from clinical and from food strains of l. monocytogenes by mitomycin c induction. the system consists of two subsystems, one of which is used to type l. monocytogenes serotype 1 strains, containing 12 phages, and a second which is used to type serotype 4 strains, containing 14 other phages. for the serotype 1 subsystem, the reproducibility was > or = 90%, the typability 92%, and the discriminatory power, as judg ... | 1993 | 8489767 |
| a proposed nonpathogenic biological indicator for thermal inactivation of listeria monocytogenes. | listeria innocua m1 was developed as a thermal processing indicator organism for l. monocytogenes by selection of a rifampin- and streptomycin-resistant mutant. zetad values were 5.6 and 5.8 degrees c, and d (68 degrees c) values were 3.8 and 4.9 s for l. monocytogenes and l. innocua, respectively, in skim milk. the advantages of easy selection, similar heat resistance, and nonpathogenicity make l. innocua m1 appropriate for challenge studies designed to evaluate process lethality with respect t ... | 1993 | 8489233 |
| oral infectivity and bacterial interactions with mononuclear phagocytes. | the purpose of this study was to clarify the association between the oral infectivity of a bacterial strain and its susceptibility to ingestion by mononuclear phagocytes or ability to survive within them. ten bacterial strains tested--all of known oral infectivity--comprised salmonella typhimurium, listeria monocytogenes (three strains), escherichia coli (two strains), proteus mirabilis, enterococcus faecalis, bacteroides fragilis, and a bacteroides sp. the phagocytic uptake of each strain was m ... | 1993 | 8487291 |
| gastrointestinal carriage of listeria monocytogenes in household contacts of patients with listeriosis. | 1993 | 8486970 | |
| growth of listeria monocytogenes and clostridium sporogenes in cottage cheese in modified atmosphere packaging. | low fat cottage cheese (ph 5.14) was inoculated with three strains of listeria monocytogenes, serotypes 1a and 4b, an isolate from a dairy processing plant, and clostridium sporogenes atcc 3584. the cheese was packaged with or without added dissolved co2 in polystyrene tubs overwrapped with or without high barrier heat shrink film and stored at 4, 7, and 21 degrees c for up to 63 d. the concentration of co2 in the container headspace was 35% (vol/vol). the co2 concentration in that headspace dec ... | 1993 | 8486848 |
| acetic, lactic and citric acids and ph inhibition of listeria monocytogenes scott a and the effect on intracellular ph. | the effects of acetic, lactic and citric acids and ph on the growth and intracellular ph (phin) of listeria monocytogenes scott a were documented and compared for total acid concentrations ranging from 50 mmol ml-1 to 250 mmol ml-1 for acetic and lactic acids and from 25 mmol ml-1 to 100 mmol ml-1 for citric acid. initial ph values ranged from 4.7 to 6.0. although the growth rate of l. monocytogenes scott a was slower when incubated at 25 degrees c than at 37 degrees c, the relative acid and ph ... | 1993 | 8486558 |
| bactericidal activity of disinfectants on listeria. | the bactericidal activity on listeria spp. of nine disinfectants used in the food industry was studied by previously published methods. the disinfectants were diluted to the test concentration in sterile standard hard water. various types of chemical agents were evaluated, including phenolic compounds, alcohols, quaternary ammonium compounds, surface-active agents, aldehydes and disochlorine tablets. the following strains isolated from cheese were studied: listeria innocua, l. welshimeri, l. mon ... | 1993 | 8486555 |
| heat resistance of listeria monocytogenes by two recovery media used with and without cold preincubation. | three strains of listeria monocytogenes were heat-treated at three temperatures in physiological saline by a capillary tube method. recovery of heat-treated bacteria was performed on blood agar and on tryptose phosphate agar with ferric citrate and aesculin (tpa-fe). both media were used in two ways: (1) incubation at 37 degrees c for 7 d, and (2) preincubation at 4 degrees c for 5 d in order to obtain repair of heat-injured bacteria, followed by incubation at 37 degrees c for 7 d. d and z value ... | 1993 | 8486551 |
| enterocin 226nwc, a bacteriocin produced by enterococcus faecalis 226, active against listeria monocytogenes. | enterococcus faecalis 226, isolated from natural whey cultures utilized as starters in the manufacture of mozzarella cheese from water-buffalo milk, produces a bacteriocin designated enterocin 226nwc. the bacteriocin was isolated from culture supernatant fluids of the producer strain and was active against strains of the same species and listeria monocytogenes, but not against useful lactic acid bacteria. enterocin 226nwc is a protein with an apparent molecular weight of about 5800; it is relati ... | 1993 | 8486543 |
| [listeria monocytogenes infection in hiv patients: 2 new cases]. | two new cases of infection due to listeria monocytogenes in two females with hiv are discussed, one of them with full blown aids and the other pregnant and without knowledge of her seropositivity until that moment. its clinical manifestation as a meningeal manifestation and bacteremia, coincide with the few cases described until now; different hypothesis invoked until now are reviewed to justify this infrequent association hiv-listeria. | 1993 | 8484037 |
| identification of a phosphoenolpyruvate:fructose phosphotransferase system (fructose-1-phosphate forming) in listeria monocytogenes. | listeria monocytogenes is a gram-positive bacterium whose carbohydrate metabolic pathways are poorly understood. we provide evidence for an inducible phosphoenolpyruvate (pep):fructose phosphotransferase system (pts) in this pathogen. the system consists of enzyme i, hpr, and a fructose-specific enzyme ii complex which generates fructose-1-phosphate as the cytoplasmic product of the pts-catalyzed vectorial phosphorylation reaction. fructose-1-phosphate kinase then converts the product of the pts ... | 1993 | 8478337 |
| characterization of an aromatic amino acid-dependent listeria monocytogenes mutant: attenuation, persistence, and ability to induce protective immunity in mice. | a transposon insertion mutant of listeria monocytogenes was shown to be deficient in prephenate dehydratase, an enzyme acting late in the pathway for biosynthesis of phenylalanine. this mutant had reduced virulence in mice. the mutant and parent strains persisted to the same extent in the tissues of infected mice and elicited similar degrees of splenomegaly. mice vaccinated with the mutant were protected significantly from subsequent challenge with virulent l. monocytogenes. | 1993 | 8478119 |
| listeria monocytogenes-induced gamma interferon secretion by intestinal intraepithelial gamma/delta t lymphocytes. | gamma/delta t cells represent a major proportion of intestinal intraepithelial lymphocytes (iel), and it has been suggested that these iel serve as a first immune barrier against microbial invasion and that they do so by destroying infected epithelial cells. in the present study, we confirm that both alpha/beta and gamma/delta iel from naive mice express potent cytotoxicity and produce gamma interferon (ifn-gamma) after t-cell receptor (tcr) engagement by specific monoclonal antibodies (mab). in ... | 1993 | 8478105 |
| directional actin polymerization associated with spotted fever group rickettsia infection of vero cells. | members of the spotted fever group (sfg) of rickettsiae spread rapidly from cell to cell by an unknown mechanism(s). staining of rickettsia rickettsii-infected vero cells with rhodamine phalloidin demonstrated unique actin filaments associated with one pole of intracellular rickettsiae. f-actin tails greater than 70 microns in length were seen extending from rickettsiae. treatment of infected cells with chloramphenicol eliminated rickettsia-associated f-actin tails, suggesting that de novo prote ... | 1993 | 8478082 |
| immunity to intracellular bacteria. | intracellular bacteria are endowed with the capacity to survive and replicate inside mononuclear phagocytes (mp) and, sometimes, within certain other host cells. mp are potent effectors cells that are able to engulf and kill many bacterial invaders. therefore, intracellular bacteria had to exploit potent evasion mechanisms that allow their survival in this hostile environment. at the early phase, natural killer cells activate antibacterial defense mechanisms. during intracellular persistence, mi ... | 1993 | 8476559 |
| listeria-associated pericarditis in an aids patient. | listeria monocytogenes is a pathogenic, facultative intracellular gram-positive rod, generally seen in cell-mediated immunocompromised states. in acquired immunodeficiency syndrome (aids), it most commonly presents as bacteremia or meningitis. an association with pericarditis has not been described previously in this group of patients. this article describes a case of pericarditis secondary to listeriosis involving a focal pancarditis and necrosis of the a-v node with subsequent refractory ventr ... | 1993 | 8474138 |
| cell-surface location of listeria-specific protein p60--detection of listeria cells by indirect immunofluorescence. | a specific polyclonal antiserum was prepared against a gel-purified 60 kda extracellular protein of listeria monocytogenes atcc 19111 corresponding to protein p60 previously detected in culture broths of l. monocytogenes strains mackaness and egd [kuhn, m. & goebel, w. (1989), infection and immunity 57, 55-61]. indirect immunogold labelling combined with transmission electron microscopy and high-resolution scanning electron microscopy were used to investigate the location and distribution of p60 ... | 1993 | 8473866 |
| ity influences the production of ifn-gamma by murine splenocytes stimulated in vitro with salmonella typhimurium. | the ity-lsh-bcg genetic locus in the mouse has been documented to confer innate resistance to at least three intracellular pathogens: salmonella typhimurium, leishmania donovani, and mycobacterium. expression of the resistance gene(s) results in a slower net growth of these pathogens in the reticuloendothelial system early postinfection. although it is clear that the resident macrophages in resistant mice are functionally superior with regard to antimicrobial activity, the exact mechanism(s) und ... | 1993 | 8473743 |
| a highly sensitive and fast nonradioactive method for detection of polymerase chain reaction products. | a novel system for the detection of polymerase chain reaction (pcr) products has been developed. the system is based on a pcr in which one of the primers is biotinylated and digoxigenin-11-dutp is incorporated during elongation. biotinylated pcr products are captured on streptavidin-coated solid supports, and alkaline phosphatase conjugated to anti-digoxigenin antibody is subsequently bound to the incorporated digoxigenin. the detection may be obtained with colorimetric, fluorescent, or luminesc ... | 1993 | 8470800 |
| mesenrhombencephalitis: mr findings in nine patients. | mesenrhombencephalitis is a serious form of brainstem inflammation predominantly involving the deep and vital portions of the brain, that is, the mesencephalon (midbrain) and rhombencephalon (pons, medulla). mesenrhombencephalitis is difficult to diagnose on the basis of clinical and laboratory findings alone, and access to this portion of the brain for surgical biopsy carries high morbidity. we describe the mr appearance of mesenrhombencephalitis and correlate the imaging findings with clinical ... | 1993 | 8470582 |
| differences in the rate of intracellular killing of catalase-negative and catalase-positive listeria monocytogenes by normal and interferon-gamma-activated macrophages. | intracellular killing of catalase-positive bacteria by murine resident macrophages requires the presence of extracellular serum, whereas killing of catalase-negative bacteria can occur in the absence of serum. to find out whether the intracellular killing of bacteria by rifn-gamma-activated macrophages also requires serum stimulation, we investigated the handling of ingested catalase-negative and -positive listeria monocytogenes by peritoneal macrophages of normal swiss mice and mice injected i. ... | 1993 | 8469926 |
| [periprosthetic popliteal abscess caused by listeria monocytogenes]. | 1993 | 8469664 | |
| separation of bacteria using agglutinins isolated from invertebrates. | the agglutination of a selection of gram-positive and gram-negative bacteria by the haemolymph and coelomic fluid from several invertebrates was studied. the haemolymph from lumbricus terrestris and limulus polyphemus caused the strongest agglutination of most of the bacteria studied. when the agglutinating fraction of lim. polyphemus was liganded to magnetic microspheres 53% of the cells in pure cultures of listeria monocytogenes c200, 15% of salmonella enteritidis 37782, 92% of staphylococcus ... | 1993 | 8468260 |
| novel mechanism for the camp reaction between listeria monocytogenes and corynebacterium equi. | the synergistic hemolytic reaction between listeria monocytogenes, staphylococcus aureus and corynebacterium equi on blood agar plates was explored using a modified test-tube assay. a synergistic lysis of sheep red blood cells was observed with l. monocytogenes and either s. aureus or c. equi, using crude extracts. synergism was also found with l. monocytogenes and purified cholesterol oxidase from pseudomonas fluorescens and brevibacterium brevi. crude extracts of s. aureus sensitized sheep red ... | 1993 | 8466816 |
| a model of food-borne listeria monocytogenes infection in the sprague-dawley rat using gastric inoculation: development and effect of gastric acidity on infective dose. | recent epidemiological evidence suggests that listeria monocytogenes (lm) is a food-borne pathogen in humans. a model of lm infection was developed using the sprague-dawley (sd) rat to study the interaction of lm with gastrointestinal epithelium as the first step in the pathogenesis of invasive listeriosis. conventionally raised, juvenile female sd rats were given 10(2)-10(9) virulent l. monocytogenes, serotype 4b or nonpathogenic listeria species. only rats given virulent lm developed dose-depe ... | 1993 | 8466809 |
| microbiological status of rabbit carcases in egypt. | a total of 40 new zealand white rabbits, 20 freshly slaughtered rabbits from an experimental farm and 20 processed rabbit carcases from grocery stores in beni-suef city, were examined bacteriologically. the mean values of aerobic plate counts at 37 degrees c and 1 degrees c, enterobacteriaceae counts, pseudomonas counts and staphylococcus counts of freshly slaughtered rabbits were 10(4) +/- 2 x 10(3), 8 x 10(2) +/- 10(2), 6 x 10(2) +/- 10(2), 3 x 10(2) +/- 10(2), and 10(2) +/- 60 organisms per g ... | 1993 | 8465608 |
| a chimeric toxin to study the role of the 21 kda gtp binding protein rho in the control of actin microfilament assembly. | we have developed a new tool for studying the role of rho in actin stress fibre formation. clostridium botulinum exoenzyme c3 which affects actin microfilament assembly by adp-ribosylation of p21 rho was genetically fused in various ways to diphtheria toxin (dt). the resulting chimeric toxins were tested on vero cells. chimeras of c3 and both the a and b fragments of diphtheria toxin had reduced cell binding activities but were apparently able to penetrate into vero cells by the same mechanism a ... | 1993 | 8458345 |
| outbreak of listeriosis in 1992. | 1993 | 8457433 | |
| immune response in mice that lack the interferon-gamma receptor. | interferon-gamma (ifn-gamma) exerts pleiotropic effects, including antiviral activity, stimulation of macrophages and natural killer cells, and increased expression of major histocompatibility complex antigens. mice without the ifn-gamma receptor had no overt anomalies, and their immune system appeared to develop normally. however, mutant mice had a defective natural resistance, they had increased susceptibility to infection by listeria monocytogenes and vaccinia virus despite normal cytotoxic a ... | 1993 | 8456301 |
| listeria monocytogenes endocarditis in a patient with a prosthetic aortic valve. | 1993 | 8454450 | |
| membrane damage and interleukin-1 production in murine macrophages exposed to listeriolysin o. | to obtain some insight into the interaction between listeriolysin o (llo) and the macrophage membrane, we examined the effect of purified listeria monocytogenes hemolysin on the viability and functions of mouse peritoneal exudate macrophages. the study showed that purified llo impaired a variety of functions of the macrophages. first, it suppressed the luminol-dependent chemiluminescence response of macrophages. second, it suppressed the phagocytic ingestion of opsonized sheep erythrocytes and l ... | 1993 | 8454336 |
| reduced ribosomal thermal denaturation in listeria monocytogenes following osmotic and heat shocks. | increased thermotolerance of listeria monocytogenes induced by exposure to a high nacl concentration or a sublethal heat shock was concurrent with increased thermal stability of the 30s ribosomal subunit as measured by differential scanning calorimetry. it is proposed that protection of the 30s subunit is a critical mechanism for increased thermotolerance. | 1993 | 8454183 |
| ethanol ingestion increases susceptibility of mice to listeria monocytogenes. | excessive consumption of alcohol is associated with an increase in the frequency and severity of infectious diseases. ethanol adversely affects specific and nonspecific aspects of the immune response. we used a murine model to determine whether ethanol ingestion impairs host mechanisms of resistance to listeria monocytogenes. naive mice and mice immune to l. monocytogenes were pair-fed either a leiber-decarli liquid diet containing 7% (v/v) ethanol or an isocaloric control diet for 7 days. then, ... | 1993 | 8452211 |
| fish oil and immune function. | 1993 | 8446307 | |
| ro 23-9424, a new cephalosporin 3'-quinolone: in-vitro antimicrobial activity and tentative disc diffusion interpretive criteria. | the susceptibility of 410 clinical bacterial isolates to ro 23-9424, a novel cephalosporin 3'-quinolone, was determined. overall, 97% of enterobacteriaceae and 100% of staphylococci were inhibited by < or = 8.0 mg/l of ro 23-9424. only 60% of pseudomonas aeruginosa and 80-90% of pseudomonas spp. and xanthomonas maltophilia were inhibited by this concentration. enterococci and listeria monocytogenes were resistant to ro 23-9424. clinical isolates of moraxella catarrhalis, streptococcus spp., and ... | 1993 | 8444677 |
| administration of dehydroepiandrosterone to burned mice preserves normal immunologic competence. | burned individuals display a reduced ability to elicit cellular and humoral immune responses and a depression in the vitro production of certain t-cell lymphokines. treatment of burned mice with 100 micrograms of dehydroepiandrosterone within 1 hour after injury resulted in preserving a completely normal capacity to produce t-cell-derived lymphokines and to generate cellular immune responses. in addition, dehydroepiandrosterone-treated thermally injured mice demonstrated an above-normal ability ... | 1993 | 8442690 |
| differentiation of listeria monocytogenes and listeria innocua by 16s rrna genes and intraspecies discrimination of listeria monocytogenes strains by random amplified polymorphic dna polymorphisms. | differences in the 16s rrna genes (16s rdna) which can be used to discriminate listeria monocytogenes from listeria innocua have been detected. the 16s rdna were amplified by polymerase chain reaction with a set of oligonucleotide primers which flank a 1.5-kb fragment. sequence differences were observed in the v2 region of the 16s rdna both between l. monocytogenes scott a and l. innocua and between different l. monocytogenes serotypes. although l. monocytogenes slcc2371 had the same v2 region s ... | 1993 | 8439157 |
| identification and enumeration of listeria monocytogenes by nonradioactive dna probe colony hybridization. | a plasmid containing the cloned listeriolysin gene of listeria monocytogenes was used as a probe to identify listeria strains by dna colony hybridization. the probe dna was labeled with horseradish peroxidase in the presence of glutaraldehyde. after the hybridization and wash procedures, the hybrid molecules were detected by luminescence, which resulted from the oxidation of luminol by a horseradish peroxidase-hydrogen peroxide-coupled reaction. of the 150 listeria strains and 16 non-listeria st ... | 1993 | 8439145 |
| comparison of conventional and reversed phage typing procedures for identification of listeria spp. | of 225 listeria isolates evaluated, 199 had the same bacteriophage patterns by both the conventional (a. audurier, a.g. taylor, b. carbonelle, and j. mclaughlin, clin. invest. med. 7:229-232, 1984) and the new, easier to apply, "reversed" (m. j. loessner, appl. environ. microbiol. 57:882-884, 1991) phage typing procedures, 5 had different phage reactions, and the remaining 21 isolates were untypeable. thus, the overall typeability rate was 90.7%, and 97.6% of the typeable isolates had the same p ... | 1993 | 8434928 |
| genetic basis of tetracycline resistance in food-borne isolates of listeria innocua. | eleven of 12 tetracycline-resistant listeria innocua strains, isolated from chicken or turkey frankfurters and mozzarella cheese, were shown to carry dna sequences which hybridized with the tet m probe; of these, two strains also hybridized with tet k. the remaining strain hybridized with the tet k probe only. the tet m determinant appeared to be located on the chromosome; in one case, it was transferable by conjugation to recipients listeria monocytogenes, listeria ivanovii, and enterococcus fa ... | 1993 | 8434927 |
| stimulating effect of deodan (an oral preparation from lactobacillus bulgaricus "lb51") on monocytes/macrophages and host resistance to experimental infections. | deodan is a lysozyme lysate from lactobacillus bulgaricus for oral administration which has shown antitumor activity in mice and humans. the effects of this preparation on some functions of monocytes/macrophages and on host resistance to experimental infections were examined. the oral administration to mice of deodan-150 mg/kg daily (the recommended dose in humans) caused an increase of the spreading ability and phagocytic activity of peritoneal macrophages, which showed morphological signs of c ... | 1993 | 8432622 |
| murine peritoneal macrophages activated by the mycobacterial 65-kilodalton heat shock protein express enhanced microbicidal activity in vitro. | after an intraperitoneal (i.p.) injection of purified protein derivative, peritoneal macrophages from mice infected with mycobacterium bovis bacillus calmette-guérin (bcg) show an enhanced respiratory burst, inhibit the intracellular proliferation of toxoplasma gondii, and kill listeria monocytogenes more efficiently than peritoneal macrophages from normal mice. one of the immunodominant antigens of mycobacterium spp. is the 65-kda heat shock protein (hsp 65), and in the present study, we determ ... | 1993 | 8432607 |
| listeria monocytogenes infection in beta 2 microglobulin-deficient mice. | beta 2 microglobulin-deficient mice, in which the beta 2m gene has been disrupted by homologous recombination, lack functional cd8 t cells and are able to contain but not resolve an intravenous immunizing inoculum of listeria monocytogenes. we present evidence that compensatory immunity in such immunodeficient mice was mediated by a population of gamma delta t-cell receptor-positive cells; in contrast, neither cd4 cells nor natural killer cells appeared to play any part in this process. these da ... | 1993 | 8432593 |
| immunotoxic effects of the color additive caramel color iii: immune function studies in rats. | administration of the color additive caramel color iii (ac) may cause a reduction in total white blood cell counts in rats due to reduced lymphocyte counts. beside lymphopenia, several other effects in rat have been described. the effects are caused by the imidazole derivative 2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole (thi) and occur in rats fed a diet low in vitamin b6. in the present paper, immune function studies on ac and thi with rats fed a diet low, but not deficient in vitamin b6 ... | 1993 | 8432426 |
| genetic characterisation of isolates of listeria monocytogenes from man, animals and food. | multilocus enzyme electrophoresis was used to assess genetic relationships between 95 isolates of listeria monocytogenes, most of which were isolated in australia and new zealand from man, animals and food. the isolates were separable into two major genetic divisions; the majority of those from human patients and animals were in division i, and the majority from those foods that were not specifically associated with human listeriosis were in division ii. isolates in division i were virulent, whe ... | 1993 | 8429537 |
| differential mechanisms of intracellular killing of mycobacterium avium and listeria monocytogenes by activated human and murine macrophages. the role of nitric oxide. | murine peritoneal macrophages activated with interferon-gamma (ifn-gamma) produce large quantities of nitric oxide and are efficient in the killing of certain intracellular pathogens. to examine the role of this mechanism in the killing of mycobacterium avium by murine and human macrophages, we infected mouse peritoneal macrophages and human monocyte-derived macrophages with m. avium and listeria monocytogenes and stimulated the cells with recombinant tumour necrosis factor (tnf), granulocyte-ma ... | 1993 | 8428392 |
| optical dna-dna homology in the genus listeria. | twenty-three strains of the seven recognized listeria species were studied by using dna-dna optical hybridization. the level of error in the data was low. our results supported the results of rocourt et al. (j. rocourt, f. grimont, p. a. d. grimont, and h. p. r. seeliger, curr. microbiol. 7:383-388, 1982), although there was some overlap between listeria monocytogenes and listeria innocua. we suggest that there may be more than one cluster in the species l. monocytogenes or the species may form ... | 1993 | 8427807 |
| lipopolysaccharide-induced selective priming effects on tumor necrosis factor alpha and nitric oxide production in mouse peritoneal macrophages. | preculture of thioglycollate-elicited c3heb/fej mouse peritoneal macrophages in vitro with subthreshold stimulatory concentrations of lipopolysaccharide (lps) can induce hyporesponsiveness (desensitization) to both tumor necrosis factor alpha (tnf-alpha) and nitric oxide (no) production when these cells are subsequently stimulated with 100 ng/ml of lps. we have established, however, that the primary dose of lps required for inducing downregulation of no production is significantly lower than tha ... | 1993 | 8426119 |
| comparative analysis of using mtt and xtt in colorimetric assays for quantitating bovine neutrophil bactericidal activity. | two different tetrazolium compounds were compared for use in a colorimetric assay for quantitating bovine neutrophil bactericidal activity against staphylococcus aureus, escherichia coli, listeria monocytogenes, and brucella abortus. the tetrazolium compounds tested included 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (mtt) and sodium 3,3'-[1[(phenylamino)carbonyl]-3,4- tetrazolium]-bis(4-methoxy-6-nitro) benzene sulfonic acid hydrate (xtt). the mtt and xtt colorimetric bacteric ... | 1993 | 8423367 |
| the effect of slurry storage and anaerobic digestion on survival of pathogenic bacteria. | the decline in viable numbers of salmonella typhimurium, yersinia enterocolitica and listeria monocytogene in beef cattle slurry is temperature-dependent; they decline more rapidly at 17 degrees c than at 4 degrees c. mesophilic anaerobic digestion caused an initial rapid decline in the viable numbers of escherichia coli, salm. typhimurium, y. enterocolitica and l. monocytogenes. this was followed by a period in which the viable numbers were not reduced by 90%. the t90 values of e. coli, salm. t ... | 1993 | 8420921 |
| purification, partial characterization and plasmid-linkage of pediocin sj-1, a bacteriocin produced by pediococcus acidilactici. | pediococcus acidilactici sj-1, isolated from a naturally-fermented meat product, produced an antibacterial agent active against selected strains of lactobacillus spp., clostridium perfringens and listeria monocytogenes. the agent was bactericidal against sensitive indicators, and sensitive to proteolytic enzymes; it was identified as a bacteriocin, and was designated as pediocin sj-1. it was stable over a wide ph range (3-9), and apparently most stable in the lower part of that range. at ph 3.6, ... | 1993 | 8420920 |
| distribution of pathogen inhibition in the lactobacillus isolates of a commercial probiotic consortium. | pure strains of lactobacillus ssp. isolated from a commercial probiotic consortium were checked in a double layer solid medium for their inhibition activities against selected pathogenic bacteria including serotypes of listeria monocytogenes, escherichia coli and salmonella. the antagonistic properties of the lactobacillus strains may be related to the production of bacteriocin-like compounds. all the pathogens tested were inhibited by one or a few strains of lactobacillus, the best inhibition w ... | 1993 | 8420917 |
| listeria ivanovii is capable of cell-to-cell spread involving actin polymerization. | listeria ivanovii has been considered to be pathogenic to animals but has rarely been found associated with human infections. it has been claimed that l. ivanovii lacks the acta gene, which in l. monocytogenes encodes a protein required for interaction with host cell actin. using fluorescence microscopy and electron microscopy, we demonstrate that l. ivanovii can invade mammalian cells, lyse the phagosomal membrane, polymerize host cell actin, reorganize actin to form tails, and spread from cell ... | 1993 | 8418038 |
| acute bacterial meningitis in adults. a review of 493 episodes. | to characterize acute bacterial meningitis in adults, we reviewed the charts of all persons 16 years of age or older in whom acute bacterial meningitis was diagnosed at massachusetts general hospital from 1962 through 1988. we included patients who were admitted after initial treatment at other hospitals. | 1993 | 8416268 |
| polarized distribution of listeria monocytogenes surface protein acta at the site of directional actin assembly. | the facultative intracellular pathogen listeria monocytogenes can infect host tissues by using directional actin assembly to propel itself from one cell into another. the movement is generated by continuous actin assembly from one end of the bacterium into a tail, which is left behind in the cytoplasm. bacterial actin assembly requires expression of the bacterial gene acta. we have used immunocytochemistry to show that the acta gene product, acta, is distributed asymmetrically on the bacterial s ... | 1993 | 8408297 |
| bacteriocinogenic activity of lactobacilli from fermented sausages. | during the screening of the inhibitory activity of 254 strains of lactobacilli isolated from fermented sausages at different times of ripening, 22% of the strains showed inhibition that was not related to acid or hydrogen peroxide, towards one or more indicator strains. not all the strains were capable of secreting the inhibitory compound in the supernatant fluid. the characterization of the inhibitory compound from three strains showed that they were bacteriocins with a bactericidal mode of act ... | 1993 | 8407674 |
| antimicrobial activity of lactic acid bacteria isolated from sour doughs: purification and characterization of bavaricin a, a bacteriocin produced by lactobacillus bavaricus mi401. | three hundred and thirty-five lactic acid bacteria were isolated from sour doughs and screened for antagonistic activity. of these 145 showed activity against one or several of the indicator strains used in the screening. the antimicrobial activity of 18 isolates were due to a proteinaceous compound. these 18 isolates belonged to three different lactobacillus species: lactobacillus bavaricus, lactobacillus curvatus and lactobacillus plantarum. the spectrum of antimicrobial activity for the three ... | 1993 | 8407671 |
| epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. | bacterial invasion of mucosal surfaces results in a rapid influx of polymorphonuclear leukocytes. the chemotactic stimulus responsible for this response is not known. since epithelial cells are among the first cells entered by many enteric pathogens, we investigated the ability of epithelial cells to provide an early signal for the mucosal inflammatory response through the release of chemotactic cytokines. as shown herein, the chemokine interleukin-8 (il-8), a potent chemoattractant and activato ... | 1993 | 8406853 |
| inhibition of interferon-gamma by an interferon-gamma receptor immunoadhesin. | interferon-gamma (ifn-gamma) is an important cytokine which regulates inflammatory and immune response mechanisms. ifn-gamma enhances the presentation and recognition of antigens by inducing the expression of major histocompatibility complex (mhc) proteins, by activating effector t cells and mononuclear phagocytes, and by modulating immunoglobulin production and class selection in b cells. inappropriate production of ifn-gamma has been implicated in the pathogenesis of several autoimmune and inf ... | 1993 | 8406584 |
| [a case of listeria rhombencephalitis with a secondary vasculitis suggested by mri]. | we reported a rare case of listeria rhombencephalitis with meningitis. a 48-year-old healthy man suddenly experienced high fever and headache, then he had lower cranial nerve's palsies and mental dysfunction developed during one week period. on admission, his temperature was 38 degrees c. he was slightly delirious and euphoric. he had nuchal rigidity, mild paresthesia over his left cheek to left upper lip, a right sixth nerve palsy, dysphagia, hiccup, nasal voice and left cerebellar ataxia. his ... | 1993 | 8403684 |
| serological response in rabbits to listeria monocytogenes after oral or intragastric inoculation. | the serological response in rabbits against listeria monocytogenes after oral or intragastric inoculation was investigated. both the number of sero-positive animals and the average serum titres were higher in animals inoculated by the oral route. this difference was especially marked in rabbits inoculated with the lower dose (1 x 10(3) colony-forming units (cfu)), which developed a strong serological response (average serum titre of 1280 after 4 inoculations) in most of the inoculated animals (8 ... | 1993 | 8401424 |
| liver abscess due to listeria monocytogenes: case report and review. | involvement of the liver in cases of listeria monocytogenes infection is uncommon but has been manifested as solitary liver abscess, multiple liver abscesses, and hepatitis. we describe a 73-year-old diabetic woman who presented with a solitary liver abscess and prolonged fever, and we review the world literature on hepatic manifestations of l. monocytogenes infection. patients presenting with solitary liver abscesses uniformly recovered with antimicrobial therapy and abscess drainage, whereas a ... | 1993 | 8399880 |
| increased risk of meningitis and bacteremia due to listeria monocytogenes in patients with human immunodeficiency virus infection. | the incidence, demographics, and clinical outcome of infections due to listeria monocytogenes in individuals infected with the human immunodeficiency virus (hiv) were evaluated by prospective population-based surveillance. during a 2-year study period, 37 cases of invasive listeriosis occurred in metropolitan atlanta (annual incidence, 0.8 case per 100,000 population). seven of these cases occurred in known hiv-infected individuals (19% of all cases); five had an aids-defining illness, and the o ... | 1993 | 8399870 |
| current microbiological considerations in food preservation. | changes in the composition and properties of certain foods, as well as development of food products to meet consumer demands relating to health, nutrition and convenience lead to concerns about the microbiological safety of such products. concerns also arise from emergence or recognition of the importance of certain microbial food pathogens or spoilage organisms, as well as from modifications in food processing, handling, storage and preparation procedures. these facts necessitate continuous ree ... | 1993 | 8398630 |
| characterization of bacteriocins from enterococcus faecium with activity against listeria monocytogenes. | laboratory cultures and environmental isolates of bacteria were screened for antagonism towards listeria monocytogenes using an agar spot test. seven of the 163 strains that were tested, one streptococcus bovis, one enterococcus casseliflavus, two e. avium and three e. faecium, consistently displayed antilisterial activity. cell-free, ph-neutralized supernatants prepared from the three e. faecium strains (jbl1061, jbl1083 and jbl1351) exhibited strong antilisterial activity against l. monocytoge ... | 1993 | 8398626 |
| free versus liposome-encapsulated muramyl tripeptide phosphatidylethanolamide (mtppe) and interferon-y (ifn-y) in experimental infection with listeria monocytogenes. | the effect of free and liposome-encapsulated muramyl tripeptide phosphatidylethanolamide (mtppe) and interferon-y (ifn-y) on the resistance against listeria monocytogenes infection in mice was investigated. it was shown that administration of mtppe or ifn-y at 24 h before bacterial inoculation led to increased resistance against l. monocytogenes infection in terms of a decrease in bacterial numbers in liver and spleen. encapsulation of mtppe and ifn-y in liposomes increased their efficacy 33- or ... | 1993 | 8398570 |
| [comparison of 3 enrichment media for the study of listeria monocytogenes in foods]. | analysis organised by the bcr (bureau communautaire de référence) using material in form of capsules containing a strain of listeria monocytogenes of known concentrations in various types of foods were carried out within the interlaboratory trials. in this work, it is demonstrated that the leb (listeria enrichment broth) medium is, of the three media assayed, the most adequate to investigate this organism in foods. | 1993 | 8397968 |
| mice lacking the tumour necrosis factor receptor 1 are resistant to tnf-mediated toxicity but highly susceptible to infection by listeria monocytogenes. | tumour necrosis factor (tnf), jointly referring to tnf alpha and tnf beta, is a central mediator of immune and inflammatory responses; its activities are mediated by two distinct receptors, tnfr1 (p55) and tnfr2 (p75) (reviewed in refs 1-3). the cytoplasmic domains of the tnfrs are unrelated, suggesting that they link to different intracellular signalling pathways. although most tnf responses have been assigned to one or the other of the tnf receptors (mostly tnfr1), there is no generally accept ... | 1993 | 8395024 |