Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| nih consensus conference: osteoporosis. factors contributing to osteoporosis. | 2013 | 3944667 | |
| nih consensus conference: osteoporosis. factors contributing to osteoporosis. | 2013 | 3944667 | |
| a functional organization of on and off pathways in the rabbit retina. | intracellular electrophysiological recordings were obtained from amacrine and ganglion cells in an isolated, superfused retina-eyecup preparation of the rabbit. cells were characterized physiologically, after which cell-staining was accomplished by intracellular iontophoresis of hrp. a computer-assisted image-processing system was used to study the dendritic stratification pattern of hrp-labeled neurons within the inner plexiform layer (ipl). our results support the concept that the ipl is funct ... | 1986 | 3944611 |
| hospitals shift toward paid medical directors. | 2013 | 3943850 | |
| characterization of estrogen and progesterone receptors and the dissociated regulation of growth and progesterone receptor stimulation by estrogen in mda-mb-134 human breast cancer cells. | we have examined the properties of the estrogen receptor and progesterone receptor in mda-mb-134 human breast cells and have evaluated the effects of estrogen on cell proliferation and progesterone receptor levels in these cells as indices of hormonal sensitivity. these cells contain high levels of estrogen receptor (approximately 1.5 pmol/mg dna) and low levels of progesterone receptor (0.15 pmol/mg dna). more than 80% of the estrogen receptor is found in the nuclear fraction in the absence of ... | 1986 | 3943090 |
| characterization of estrogen and progesterone receptors and the dissociated regulation of growth and progesterone receptor stimulation by estrogen in mda-mb-134 human breast cancer cells. | we have examined the properties of the estrogen receptor and progesterone receptor in mda-mb-134 human breast cells and have evaluated the effects of estrogen on cell proliferation and progesterone receptor levels in these cells as indices of hormonal sensitivity. these cells contain high levels of estrogen receptor (approximately 1.5 pmol/mg dna) and low levels of progesterone receptor (0.15 pmol/mg dna). more than 80% of the estrogen receptor is found in the nuclear fraction in the absence of ... | 1986 | 3943090 |
| prevalence of hypertension, obesity and smoking in three indian communities in northwestern ontario. | hypertension is perceived to be an important problem among native people in canada, but specific prevalence data have not been accumulated. a study was carried out to determine community levels of blood pressure and to document the prevalence of hypertension, obesity and cigarette smoking in nonurban indians in three communities in northwestern ontario. of the 678 people present in the communities at the time of the survey 668 (98.5%) participated. age- and sex-specific mean diastolic and systol ... | 2013 | 3942942 |
| fate of n-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats. | n-(2-hydroxypropyl)methacrylamide (hpma) copolymers bearing galactosamine residues accumulate in the liver after intravenous administration to rats (duncan, r., kopecek, j., rejmanová, p. and lloyd, j.b. (1983) biochim. biophys. acta 755, 518-521). in this study hpma copolymers bearing pendent galactosamine residues (1.0-11.6 mol%) were injected intravenously into rats and their rates of blood clearance and liver accumulation were measured. a level of substitution of 4 mol% was found to be suffi ... | 1986 | 3942780 |
| iodipamide uptake by rat liver plasma membrane vesicles enriched in the sinusoidal fraction: evidence for a carrier-mediated transport dependent on membrane potential. | iodipamide, a cholecystographic agent, is known to be taken up by isolated hepatocytes by a mechanism similar or identical with the inward transport of bile salts (petzinger, e., joppen, c. and frimmer, m. (1983) naunyn-schmiedeberg's arch. pharmacol. 322, 174-179). to elucidate its mode of transport, uptake of iodipamide was studied by rapid-filtration techniques on plasma membrane vesicles enriched in the sinusoidal fraction. uptake was found to be dependent upon the temperature, the intravesi ... | 1986 | 3942739 |
| the addition of nitrous oxide to halothane decreases renal and splanchnic flow and increases cerebral blood flow in rats. | thirteen male sprague-dawley rats were anaesthetized with halothane and catheters were placed in the femoral artery and left ventricle. the animals breathed spontaneously through a tracheostomy throughout the investigation. after the surgical preparation, the inspired halothane concentration was maintained at 1.5 vol% (f/o2 = 0.3). after a 30-min stabilization period, strontium-85 radiolabelled microspheres (15 +/- 1 micron) were injected to the left ventricle for determination of cardiac output ... | 1986 | 3942673 |
| the addition of nitrous oxide to halothane decreases renal and splanchnic flow and increases cerebral blood flow in rats. | thirteen male sprague-dawley rats were anaesthetized with halothane and catheters were placed in the femoral artery and left ventricle. the animals breathed spontaneously through a tracheostomy throughout the investigation. after the surgical preparation, the inspired halothane concentration was maintained at 1.5 vol% (f/o2 = 0.3). after a 30-min stabilization period, strontium-85 radiolabelled microspheres (15 +/- 1 micron) were injected to the left ventricle for determination of cardiac output ... | 1986 | 3942673 |
| familial association of intracranial aneurysms and multiple congenital anomalies. | the familial occurrence of intracranial aneurysms and the possible relationship with connective tissue disease are discussed. we studied a large family in which seven members presented with aneurysms. another family member presented with a subarachnoidal hemorrhage. two other family members each presented with marfan's syndrome and an unclassified multiple congenital anomalies syndrome, respectively. the multiplicity of the aneurysms in four members is in excess of that found in sporadic or fami ... | 2014 | 3942510 |
| heat shock elicits production of sexual inducer in volvox. | in the green alga volvox carteri, heat shock had an unusual and adaptive effect mediated by induced production of a well-defined effector molecule. females of this species normally reproduce asexually in the absence of a potent sexual inducer produced by mature sexual males, but they generated egg-bearing sexual daughters after a brief exposure to elevated temperatures. this response involved an "autoinduction" of sexuality, in which heat-shocked somatic cells made and released the sexual induce ... | 2013 | 3941891 |
| paget's disease. | 2013 | 3941642 | |
| aging enhances the insulin resistance in obesity through both receptor and postreceptor alterations. | the association between aging and insulin resistance is well recognized. to clarify possible mechanisms, both the binding and the action of insulin were studied in abdominal sc fat cells from two groups of obese nondiabetic women matched for relative weight and fasting insulin levels. the age ranges of the two groups were 16-37 (mean, 28) and 47-77 (mean, 61) yr, respectively. insulin binding was significantly decreased in the elderly (approximately 40%; p less than 0.05), which scatchard analys ... | 2014 | 3941163 |
| contribution of the adrenal gland to the production of androstenedione and testosterone during the first two years of life. | androstenedione and testosterone were measured in whole adrenal glands of 56 previously healthy boys who died suddenly between birth and 2 yr of age. in each adrenal gland, the concentration of androstenedione considerably exceeded that of testosterone. the highest concentrations were found during the first week of life (median, 295 ng/g; range, 98-320 ng/g). thereafter, values decreased rapidly until the end of the first year of life (median, 10 ng/g; range, 4.4-22.7 ng/g). adrenal testosterone ... | 2014 | 3941161 |
| fluoropyrimidine-mediated changes in small nuclear rna. | studies were completed to examine the effects of the antineoplastic agent 5-fluorouridine (furd) on the metabolism of the small molecular weight nuclear rna (snrna). cultured sarcoma-180 murine tumor cells were exposed to furd concurrent with [3h]cytidine for 6 h, the drug was removed, and the rna was isolated at 0, 24, or 48 h following the drug treatment. the results of these studies demonstrated that furd produced three dose-dependent changes in snrna metabolism. the electrophoretic migration ... | 2014 | 3941072 |
| [intracranial pressure measurement in pediatrics--technic, indications and therapy possibilities]. | 2014 | 3940858 | |
| diflunisal interference with determination of salicylate by the trinder, abbott tdx, and du pont aca methods. | 2014 | 3940724 | |
| [in vitro toxicity of several self-curing acrylic resins (i)]. | 2014 | 3939461 | |
| [survival of campylobacter jejuni in drinking water, river water and sewage]. | campylobacter jejuni (c. jejuni) has not been found by us in raw sewage or anaerobically stabilized sludge. therefore the survival of c. jejuni has been tested in drinking water, river water and sewage. a suspension of about 10(7) c. jejuni per ml was filled into dialysis tubes which were placed in wire baskets and exposed. exposition to drinking water was done using two continuously perfused containers in the laboratory, whereas exposition to sewage and river-water was performed at the local se ... | 1985 | 3939052 |
| [effect of various factors on in vitro fertilization (ivf) and embryo transfer in the human in clomiphene/hmg/hcg stimulated cycles]. | in the present study we tried to analyse data obtained on the occasion of an in vitro fertilization programme at the department of obstetrics and gynecology of the university of kiel, to extract some of the important factors, because their positive or negative influence on the success of extracorporal insemination, embryo transfer and implantation has not been clearely defined till now and to value their concern. between july 1982 and february 1983 105 sterile patients with ovulatory menstrual c ... | 1985 | 3938148 |
| on steroid noradrenergic system interaction during the hypothalamic differentiation period in the female rat. | neonatal administration of alpha-methyl-p-tyrosine, alpha-mpt, (1 mg s.c. on days 4 and 5) or 6-hydroxydopamine, 6-ohda, (100 or 600 micrograms s.c. on day 1) did not produce any change of the reproductive function in female rats. both drugs were unable to prevent the anovulatory syndrome induced by the administration on day 4 of testosterone propionate, tp, (25 micrograms) or estradiol benzoate, eb, (10 micrograms), but blocked the precocious vaginal opening induced by eb neonatal administratio ... | 1985 | 3937738 |
| light chain germ-line genes and the immune response to 2-phenyloxazolone. | direct sequencing of mrna has shown that the early primary response of the balb/c mouse to the hapten 2-phenyloxazolone is dominated by antibodies with a particular light chain, v kappa-ox1. although the v kappa-ox1 sequence is still commonly expressed later in the response it now includes a number of nucleotide changes. from two independent balb/c germ-line dna libraries 13 different genes hybridizing to a v kappa-ox1 probe were isolated and characterized. two are identical to mrna sequences fo ... | 1985 | 3937727 |
| light chain germ-line genes and the immune response to 2-phenyloxazolone. | direct sequencing of mrna has shown that the early primary response of the balb/c mouse to the hapten 2-phenyloxazolone is dominated by antibodies with a particular light chain, v kappa-ox1. although the v kappa-ox1 sequence is still commonly expressed later in the response it now includes a number of nucleotide changes. from two independent balb/c germ-line dna libraries 13 different genes hybridizing to a v kappa-ox1 probe were isolated and characterized. two are identical to mrna sequences fo ... | 1985 | 3937727 |
| assessment by a two-site enzyme immunoassay of human epidermal growth factor (urogastrone) in the urine of patients with various gastrointestinal diseases including malignant tumors. | by using our two-site enzyme immunoassay (eia) system, the levels of human epidermal growth factor (hegf) in the urine of patients with various gastrointestinal diseases including malignant tumors were measured. urinary excretion of hegf in patients having undergone gastric resection, expressed as a function of creatinine, was found to be somewhat decreased. while the levels of hegf in patients with gastric cancer were significantly increased. then, the molecular features of hegf in the urine of ... | 1985 | 3937528 |
| influence of benzodiazepine (diazepam) by single and repeated treatment on the growth of tetrahymena. | diazepam at 10(-7) m stimulated considerably the growth of tetrahymena. the growth rate increase was still demonstrable after 3 days (after about 15 generations) and was even greater than initially. a second treatment with diazepam did not furthermore increase the growth rate. | 2014 | 3937525 |
| ghrf test in acromegalic patients for the evaluation of therapeutic results. | we studied here the clinical significance of ghrf test in evaluating therapeutic results in patients with acromegaly. three cases of acromegaly were studied at pre- and posttreatment. case 1 is a 42 year old woman, and her plasma gh showed slight increases responding to trh and arginine administration before therapy. eleven years after the pituitary irradiation, basal plasma gh decreased to low normal ranges and showed no response to the above two agents. only an insufficient increase in plasma ... | 1985 | 3937295 |
| essential cryoglobulinaemia: a clinical course lasting 25 years. | the clinical course of a patient is described whose primary manifestations of a circulating cryo iggk were cutaneous symptoms of pain, vascular purpura and necrotic ulcerations, especially of the lower extremities. a biopsy specimen of skin lesions showed vasculitis and immune reactants in the vessel walls. the aetiology was not recognized. the effect of primary long-term therapy with prednisone was not essential. combined therapy with cyclophosphamide and plasmapheresis allowed a satisfactory i ... | 2014 | 3937223 |
| [diagnostic contribution of computer tomography in muscular pathology]. | ct analysis in 26 patients with well-identified muscle diseases, and 4 normal controls was performed to evaluate its diagnostic interest. scans were obtained through pelvis, thigh and calves at comparable levels in all subjects. results showed that elementary changes were devoid of specificity and density measurements did not significantly increase the diagnostic significance of images. a good correlation was found between the degrees of ct changes and clinical evaluation of the muscles. however ... | 2013 | 3937199 |
| inhibition of the differentiation of candida albicans by the chelator 1,10-phenanthroline. | several chelators were examined for their ability to prevent the synchronous release of 24- to 48-hour stationary phase singlet cells of the dimorphic yeast candida albicans into either the mycelial or the budding phenotypes (in a defined liquid medium at 37 degrees c; at ph 6.5 or ph 4.5, respectively). the only chelator that was found to inhibit mycelium formation completely and to restrict bud formation to about 10% was 1,10-phenanthroline at minimal concentrations of 50 microm and 230 microm ... | 1985 | 3937057 |
| cardiac accumulation of trihexosylceramide in a case with amyotrophic lateral sclerosis. | 2014 | 3936950 | |
| refractory condylomata acuminata: a controlled clinical trial of carbon dioxide laser versus conventional surgical treatment. | uncontrolled trials indicate that treatment of condylomata acuminata with the carbon dioxide laser is effective and probably superior to conventional surgical treatment. we performed a controlled study of refractory condylomata acuminata to clarify whether this is the case. in this randomised trial 21 patients were treated with the carbon dioxide laser and 22 by conventional surgery after having been treated with podophyllin for an average of 33 and 35 weeks respectively. five and seven patients ... | 2013 | 3936774 |
| refractory condylomata acuminata: a controlled clinical trial of carbon dioxide laser versus conventional surgical treatment. | uncontrolled trials indicate that treatment of condylomata acuminata with the carbon dioxide laser is effective and probably superior to conventional surgical treatment. we performed a controlled study of refractory condylomata acuminata to clarify whether this is the case. in this randomised trial 21 patients were treated with the carbon dioxide laser and 22 by conventional surgery after having been treated with podophyllin for an average of 33 and 35 weeks respectively. five and seven patients ... | 2013 | 3936774 |
| cigarette smoking, gastric acid secretion, and serum pepsinogen i concentrations in duodenal ulcer patients. | cigarette smoking has been linked with duodenal ulcer disease although the mechanism of this association is unclear. this study assessed basal gastric secretory response to acute smoking of smokers with an active duodenal ulcer; in addition the possible effects of chronic smoking on gastric secretory capacity, as expressed by pentagastrin stimulated gastric acid secretion and fasting serum pepsinogen i (pg i) concentrations, were investigated in patients with active duodenal ulcer, or non-ulcer ... | 2013 | 3936754 |
| cigarette smoking, gastric acid secretion, and serum pepsinogen i concentrations in duodenal ulcer patients. | cigarette smoking has been linked with duodenal ulcer disease although the mechanism of this association is unclear. this study assessed basal gastric secretory response to acute smoking of smokers with an active duodenal ulcer; in addition the possible effects of chronic smoking on gastric secretory capacity, as expressed by pentagastrin stimulated gastric acid secretion and fasting serum pepsinogen i (pg i) concentrations, were investigated in patients with active duodenal ulcer, or non-ulcer ... | 2013 | 3936754 |
| 123i-phenylpentadecanoic acid as a tracer of cardiac free fatty acid metabolism. experimental and clinical results. | metabolism of 15(p-123i-phenyl-) pentadecanoic acid (i-ppa) was investigated in langendorff perfused rat hearts, fasted wistar rats, pentobarbital-anaesthetized dogs and, in clinical studies, in patients with coronary artery disease. in murine experiments metabolism of i-ppa was compared quantitatively with 1-14 c-palmitic acid in double tracer studies. in these experiments i-ppa is taken up and metabolized very similarly to palmitic acid. metabolic intervention studies showed identical directio ... | 1985 | 3936714 |
| 123i-phenylpentadecanoic acid as a tracer of cardiac free fatty acid metabolism. experimental and clinical results. | metabolism of 15(p-123i-phenyl-) pentadecanoic acid (i-ppa) was investigated in langendorff perfused rat hearts, fasted wistar rats, pentobarbital-anaesthetized dogs and, in clinical studies, in patients with coronary artery disease. in murine experiments metabolism of i-ppa was compared quantitatively with 1-14 c-palmitic acid in double tracer studies. in these experiments i-ppa is taken up and metabolized very similarly to palmitic acid. metabolic intervention studies showed identical directio ... | 1985 | 3936714 |
| evaluation of chemotherapy with benznidazole and nifurtimox in mice infected with trypanosoma cruzi strains of different types. | a test was made of the susceptibility of 30 strains of trypanosoma cruzi to chemotherapy with nifurtimox (bay 2502) and benznidazole (ro 7-1051). the strains had previously been classified as type i, ii, or iii according to their morphobiological and isoenzymic characteristics. three type i strains, 14 type ii strains, and 13 type iii strains were studied. mice were infected with 2 x 10(5) blood forms of these parasites and treated for 90 days with benznidazole or nifurtimox. all the surviving m ... | 1985 | 3936634 |
| [exchange transfusion in the treatment of the hemophilic child with factor viii inhibitors]. | 2014 | 3936511 | |
| [quantitative determination of bacterial endotoxins by the chromogenic limulus method: critical analysis and study of interactions between 3 divalent cations]. | the reproducibility of the limulus amoebocyte lysate (lal) test with the use of a chromogenic substrate was evaluated in the presence of 5 bacterial endotoxins (2 from escherichia coli, 1 from salmonella, 1 from serratia marcescens and 1 from vibrio cholerae) and the fda reference endotoxin ec5. endotoxins from e. coli 055b5, s. marcescens and v. cholerae were significantly more active than the reference endotoxin (p less than 0.01). addition of mg2+ activated the lal chromogenic reaction (optim ... | 1985 | 3936399 |
| drg impact on nursing care. | 2013 | 3936019 | |
| drg impact on nursing care. | 2013 | 3936019 | |
| cervical diastematomyelia. | 2014 | 3935949 | |
| health programme evaluation. | 2013 | 3935719 | |
| health programme evaluation. | 2013 | 3935719 | |
| [placement of feeding tubes]. | 2013 | 3935403 | |
| [placement of feeding tubes]. | 2013 | 3935403 | |
| kinetic mechanisms of two nad:arginine adp-ribosyltransferases: the soluble, salt-stimulated transferase from turkey erythrocytes and choleragen, a toxin from vibrio cholerae. | a subunit of choleragen and an erythrocyte adp-ribosyltransferase catalyze the transfer of adp-ribose from nad to proteins and low molecular weight guanidino compounds such as arginine. these enzymes also catalyze the hydrolysis of nad to nicotinamide and adp-ribose. the kinetic mechanism for both transferases was investigated in the presence and absence of the product inhibitor nicotinamide by using agmatine as the acceptor molecule. to obtain accurate estimates of kinetic parameters, the trans ... | 1985 | 3935159 |
| regulation of toxin biosynthesis by plasmids in vibrio cholerae. | vibrio cholerae strain 569b inaba harbouring p plasmid produced less toxin than the parent strain. to examine the effect of plasmid loss on toxin production, temperature-sensitive (ts) mutants of p, unable to replicate at 42 degrees c, were isolated. one ts plasmid was unstable at 42 degrees c and its loss yielded a cured strain that resumed a normal level of toxin biosynthesis characteristic of the plasmid-free parent strain. toxin production was again suppressed in the cured strain after reacq ... | 1985 | 3934328 |
| modified taurocholate-tellurite-gelatin agar for improved differentiation of vibrio species. | a total of 78 strains, representing 21 vibrio species, were examined by using taurocholate-tellurite-gelatin agar (ttga) medium and modified ttga medium containing 4-methylumbelliferyl-beta-d-galactoside (150 micrograms/ml). modified ttga medium allowed for simple and direct detection of beta-d-galactosidase (beta-gal) activity. this feature, in conjunction with other differential characteristics of ttga medium, gave improved differentiation of the vibrios tested. the modified ttga medium allowe ... | 1985 | 3934207 |
| possible non-involvement of lipoxygenase pathway in the cerebral blood flow decrease due to indomethacin. | indomethacin (10n mg/kg i.p.) induced a marked decrease in local cerebral blood flow (l.cbf), which was measured in the frontal cortex of unanesthetized rats by the hydrogen clearance technique. brain prostaglandins (pgd2, pge2, pgf2 alpha,) and 6kpgf1 alpha the stable metabolite of prostacyclin, were significantly decreased. treatments with inhibitors of lipoxygenase (bw 755c and nordihydroguaiaretic acid) and with fpl 55712, a leukotriene receptor antagonist, did not influence the effect of in ... | 1985 | 3933988 |
| blood transfusion and colorectal cancer. | 2013 | 3933631 | |
| blood transfusion and colorectal cancer. | 2013 | 3933631 | |
| specificity of the histone lysine methyltransferases from rat brain chromatin. | the histone lysine methyltransferases catalyze the transfer of methyl groups from s-adenosylmethionine to specific epsilon-n-lysine residues in the n-terminal regions of histones h3 and h4. these enzymes are located exclusively within the nucleus and are firmly bound to chromatin. the chromosomal bound enzymes do not methylate free or nonspecifically associated histones, while histones h3 and h4 within newly synthesized chromatin are methylated. these enzymes can be solubilized by limited digest ... | 1985 | 3933570 |
| ehlers-danlos syndrome and diverticula of the bladder. | cases of two boys, 6 and 4 years old respectively, with ehlers-danlos syndrome (eds) and large bladder diverticula, are reported. diverticulectomies were performed, but large diverticula reappeared in both patients. a connection between the increased extensibility of the connective tissue in eds and the development of bladder diverticula is suggested. | 2014 | 3933206 |
| [is there a nurse in the room? a regional survey on nursing service]. | 2014 | 3933092 | |
| attenuated response to nomifensine in rats during a swim test following lesion of the habenula complex. | male lister rats with bilateral lesions of the habenula nuclei were observed during two consecutive phases of a swim test. during the first phase of the test, when escape was not possible, lesioned animals demonstrated fewer changes of behaviour. lesioned animals failed to utilise an introduced external cue and escape route in the second part of the test. control rats treated with the antidepressant nomifensine showed few changes of behaviour during the inescapable phase of the test but an enhan ... | 1985 | 3933041 |
| [characteristic of vibrio cholerae o1 isolated in the aja river]. | 1985 | 3932541 | |
| [studies on a cytotoxic principle of non-o1 vibrio cholerae]. | 1985 | 3932533 | |
| construction and closure of the transverse loop colostomy. | the clinical courses of 211 patients having transverse loop colostomies performed during the years 1969 to 1980 in the stockholm region were examined to evaluate problems connected with construction and closure. forty-seven percent of these stomas became permanent. the morbidity rate for colostomy construction and closure seemed to be independent of the operative techniques used, the underlying disease, and the timing of closure. thus, early closure (within six to eight weeks after construction) ... | 2014 | 3932038 |
| timing of lumbar puncture in severe childhood meningitis. | 2014 | 3931817 | |
| gastrointestinal haemorrhage complicating wegener's granulomatosis. | 2014 | 3931744 | |
| synthesis of dihomoprostaglandins from adrenic acid (7,10,13,16-docosatetraenoic acid) by human endothelial cells. | human umbilical vein endothelial cells were found to contain adrenic acid (22:4) in their cellular lipids. since this fatty acid may be metabolized by cyclooxygenase in the kidney, the metabolism of adrenic acid was studied in endothelial cell cultures. [14c]adrenic acid was metabolized to several more polar metabolites. two of these metabolites co-migrated on hplc with 1 alpha,1 beta-dihomo-8-ketoprostaglandin f1 alpha (the metabolite of 1 alpha, 1 beta-dihomoprostaglandin i2) and 1 alpha,1 bet ... | 1985 | 3931686 |
| tailoring a time-bomb. inadvertent genetic engineering. | 1985 | 3931520 | |
| characterisation of mononuclear cell infiltrates by monoclonal antibodies in normal and neoplastic colorectal tissue. | 2013 | 3931427 | |
| [are parenteral high caloric intakes always justified initially in resuscitation?]. | 2014 | 3931202 | |
| the stimulations of arachidonic acid metabolism by recombinant murine interleukin 1 and tumor promoters or 1-oleoyl-2-acetyl-glycerol are synergistic. | recombinant murine il 1 stimulated arachidonic acid metabolism by rat liver cells (the c-9 cell line) and squirrel monkey smooth muscle cells, and in the presence of tumor promoters this stimulation was synergistic. in the rat liver cells that had been prelabeled with [3h]arachidonic acid, the release of 6-keto-pgf1 alpha and arachidonic acid also was stimulated by the il 1, and this release was synergistic in the presence of tpa. 1-oleoyl-2-acetyl-glycerol (oag) stimulated prostaglandin product ... | 1985 | 3930604 |
| molecular epidemiology of bacterial infections. | this article presents a review of current experience with the restriction enzyme technique in the epidemiology of bacterial infections. it is concluded that this technique has great potential, and that its practical value has been proved under a number of different epidemiologic conditions. | 1985 | 3930133 |
| t-lymphocyte subset phenotypes: a multisite evaluation of normal subjects and patients with aids. | the present study was undertaken to determine normal ranges for blood lymphocytes labeled with the monoclonal antibodies okt3, okt11, okt4, and okt8 and for the okt4/okt8 ratio. in addition, 26 patients with aids, 51 aids suspects, and 44 patients with infections were studied. the results of these determinations from six different study sites indicate that there is excellent intersite agreement in normal values obtained. these normal ranges may be used in clinical laboratory reporting. data from ... | 2014 | 3930126 |
| binding characteristics of anti-rh0(d) antibodies to rh0(d)-positive and du red cells. | the relation of human erythrocyte rh0(d) to du sites is an important unresolved question in the field of immunohematology. to compare the immunological reactivity of rh0(d)-positive and du erythrocytes, the binding characteristics of two anti-rh0(d) antisera to human rh0(d)-positive and du ("low-grade") erythrocytes were studied. 14c-protein a and direct antibody-labeled techniques were used to generate binding curves and to derive double-reciprocal plots. the results show that the number of ant ... | 1985 | 3929857 |
| metabolism of 1-naphthol by tyrosinase. | 1-naphthol was metabolized by the polyphenol oxidase, tyrosinase, primarily to 1,2-naphthoquinone and to small amounts of 1,4-naphthoquinone as well as to covalently bound products. the inhibition of covalent binding by ethylenediamine, which reacts specifically with 1,2-naphthoquinone but not 1,4-naphthoquinone, suggested that most of the covalent binding was due to 1,2-naphthoquinone or a metabolite of similar structure. the activation by tyrosinase of 1-naphthol to covalently bound products s ... | 2014 | 3929786 |
| an analysis of in vitro t cell responsiveness in lepromatous leprosy. | in lepromatous leprosy, there is extensive replication of mycobacterium leprae (m. leprae) within dermal macrophages. this lack of microbial resistance has been attributed to a defective cell-mediated immune response to m. leprae antigens. we have examined the in vitro response of t cells to m. leprae to determine if hyporesponsiveness could be reversed. the study included 40 unselected patients from new york and from colombia, most with the severe lepromatous form of the disease. we first noted ... | 1985 | 3928804 |
| electroimmunoassay of rat apolipoproteins a-i, a-iv, and e. a procedure for sample treatment to increase the sensitivity in diluted fractions. | methods for the quantitative determination of rat apolipoproteins a-i, a-iv, and e by electroimmunoassay are described. apolipoproteins present in diluted samples of biological fluids (approx. 2 ml) were concentrated by precipitation with deoxycholate and trichloroacetic acid. the protein pellets were solubilized in 0.1 ml of 0.5 m naoh and these samples were delipidated with tetramethylurea and assayed. this protocol enables the measurement of apolipoprotein concentrations that are at least 10 ... | 1985 | 3928792 |
| surgical crown lengthening: a rationale and case presentation. | 2013 | 3928709 | |
| interaction of factor xii, high-molecular-weight (hmw) kininogen and prekallikrein with sulfatide: analysis by fluorescence polarization. | the interaction of high-molecular-weight (hmw) kininogen, factor xii and prekallikrein with sulfatide was studied by fluorescence polarization. fluorescein-conjugated derivatives of hmw kininogen, factor xii and prekallikrein were prepared by reacting the purified bovine factors with fluorescein isothiocyanate (fitc). the apparent dissociation constant (kd) for the binding of fitc-labeled hmw kininogen (f-hmw kininogen) with sulfatide was calculated to be 3.2 (+/- 0.3) x 10(-8) m. this binding w ... | 1985 | 3928613 |
| eye-specific segregation of optic afferents in mammals, fish, and frogs: the role of activity. | eye-specific patches or stripes normally develop in the visual cortex and superior colliculus of many (but not all) mammals and are also formed, after surgically produced binocular innervation, in the optic tectum of fish and frogs. the segregation of ocular dominance patches or columns has been studied using a variety of anatomical pathway-tracing techniques, by electrophysiological recording of postsynaptic units or field potentials, and by the 2-deoxyglucose method following visual stimulatio ... | 1985 | 3928161 |
| activity-dependent synaptic stabilization in development and learning: how similar the mechanisms? | 2013 | 3928160 | |
| food-borne pathogens of recent concern. | 1985 | 3927947 | |
| [primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden]. | 2011 | 3927607 | |
| structure and expression of adenovirus type 12 e1b 58k protein in infected and transformed cells: studies using antibodies directed against a synthetic peptide. | we have studied the kinetics of synthesis of the early adenovirus type 12 (ad12) e1b 58k tumor antigen during lytic infection and analysed its half-life, intracellular localization and phosphorylation in infected kb and transformed hamster (ha12/7) cells. our analysis has been based on immunoprecipitations using antibodies directed against a synthetic peptide corresponding to the carboxy-terminal end of the e1b 58k protein. its synthesis was first detectable approximately 8 h after infection and ... | 1985 | 3927602 |
| [deficiencies of the prostaglandin system: iii. a partial thromboxane synthetase defect]. | the case is presented of a 67 year-old female patient suffering from an increased bleeding tendency for the past 10 years. the examinations performed to date had been completely negative. an inborn (?) partial thromboxane synthetase deficiency was now diagnosed on the basis of the platelet function parameters. | 2011 | 3927594 |
| [use of combined preparations in the treatment of ischemic heart disease]. | 2011 | 3927590 | |
| [contribution of paramedical health personnel to sociopolitical activity]. | 2013 | 3927574 | |
| genetic analysis of spo0a and spo0c mutants of bacillus subtilis with a phi 105 prophage merodiploid system. | an 8.0-kilobase chromosomal fragment of bacillus subtilis which contained an intact spo0a gene was recloned onto temperate phage phi 105 from the rho 11dspo0a+-1 transducing phage. a specialized transducing phage, phi 105-dspo0a+-1, was constructed and used to transduce the spo0a12 mutant strain 1s9. a spo+ transductant which was a single lysogen of the phi 105dspo0a+-1 transducing phage was isolated. from competent cells of this spo+ transductant was isolated a spo- (spo0a) strain which was imm ... | 1985 | 3926745 |
| genetic analysis of spo0a and spo0c mutants of bacillus subtilis with a phi 105 prophage merodiploid system. | an 8.0-kilobase chromosomal fragment of bacillus subtilis which contained an intact spo0a gene was recloned onto temperate phage phi 105 from the rho 11dspo0a+-1 transducing phage. a specialized transducing phage, phi 105-dspo0a+-1, was constructed and used to transduce the spo0a12 mutant strain 1s9. a spo+ transductant which was a single lysogen of the phi 105dspo0a+-1 transducing phage was isolated. from competent cells of this spo+ transductant was isolated a spo- (spo0a) strain which was imm ... | 1985 | 3926745 |
| lysine availability in flash-dried blood meals for swine. | the available lysine content of three flash-dried blood meals was determined by use of a pig growth assay. pigs that were 5 to 6 wk old were fed either one of the reference diets or one of the test diets for the 4-wk period of each assay. the reference diets were a corn-soybean meal basal (b) that was deficient in lysine, b+.1% l-lysine and b+.2% l-lysine. the test diets were b plus 1.5% and 3.0% of blood meal. the available lysine levels (percentage as fed) of ring-dried cattle blood meal, ring ... | 1985 | 3926739 |
| lysine availability in flash-dried blood meals for swine. | the available lysine content of three flash-dried blood meals was determined by use of a pig growth assay. pigs that were 5 to 6 wk old were fed either one of the reference diets or one of the test diets for the 4-wk period of each assay. the reference diets were a corn-soybean meal basal (b) that was deficient in lysine, b+.1% l-lysine and b+.2% l-lysine. the test diets were b plus 1.5% and 3.0% of blood meal. the available lysine levels (percentage as fed) of ring-dried cattle blood meal, ring ... | 1985 | 3926739 |
| enhancement of enterotoxin production by carbon dioxide in vibrio cholerae. | we found that vibrio cholerae 569b produced much more cholera enterotoxin in the presence of added carbon dioxide than in its absence. an atmosphere of 10% carbon dioxide was optimal for maximal enterotoxin production. | 1985 | 3926652 |
| [treatment of full-thickness burns with autologous epidermal cell grafting]. | 2014 | 3926264 | |
| [pharmacological study of benzylpenicillin-benzamido-methyl ester. i. in vivo chemotherapeutic properties]. | 1985 | 3925715 | |
| biochemical and cellular pharmacology of cytosine arabinoside. | 2014 | 3925560 | |
| urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by d-serine and maleic acid. | in several models of acute renal failure leakage of glomerular filtrate out of the tubule is an important pathogenetic mechanism; however, bidirectional diffusion of solute to account for certain pathophysiologic features of acute renal failure has received meager attention. using micropuncture and clearance methods, we assessed sequentially leakage of solutes and inulin across proximal straight tubules (pst) injured by two nephrotoxins. in d-serine-treated rats with extensive necrosis of pst, t ... | 1985 | 3925238 |
| [a case of cholera in japan with severe diarrhea and rhabdomyolysis followed by long-term excretion of v. cholerae]. | 1985 | 3925050 | |
| carriage of neisseria meningitidis and neisseria lactamica in a school population during an epidemic period in spain. | a study was made of the incidence of neisseria meningitidis and n. lactamica in a school population; 2470 children aged between 5 and 7 years were studied from four schools in alcala de henares (madrid). nasopharyngeal swabs were taken in june, november and march, between 1979 and 1983. in all the surveys except one, the proportion of carriers of n. lactamica was higher than that of n. meningitidis, reaching a ratio of about 2:1 in the complete study. the predominant serogroup of meningococcus f ... | 1985 | 3924995 |
| a 2,4-dichlorophenyl diazonium-based method for total bilirubin without interference from indican in uremic sera. | comparison of total bilirubin quantification by a 2,4-dichlorophenyl diazonium method (2,4-dcpd) with a jendrassik-grof type of method showed excellent correlation for randomly selected sera. however, sera from uremic patients on chronic hemodialysis showed a marked positive bias for the 2,4-dcpd result as compared with the jendrassik-grof result. the mean difference was 5.3 mg/l, and resulted in about 20% of the hemodialysis patients having bilirubin values greater than 13 mg/l, the upper limit ... | 2013 | 3924443 |
| a 2,4-dichlorophenyl diazonium-based method for total bilirubin without interference from indican in uremic sera. | comparison of total bilirubin quantification by a 2,4-dichlorophenyl diazonium method (2,4-dcpd) with a jendrassik-grof type of method showed excellent correlation for randomly selected sera. however, sera from uremic patients on chronic hemodialysis showed a marked positive bias for the 2,4-dcpd result as compared with the jendrassik-grof result. the mean difference was 5.3 mg/l, and resulted in about 20% of the hemodialysis patients having bilirubin values greater than 13 mg/l, the upper limit ... | 2013 | 3924443 |
| the short life of a terminal care support team: experience at charing cross hospital. | 2013 | 3924296 | |
| the short life of a terminal care support team: experience at charing cross hospital. | 2013 | 3924296 | |
| educating the doctor: postgraduate, vocational, and continuing education. | 2013 | 3924267 |