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biochemistry of muscle fatigue.fatigue--or decrease in force generation--is a reduction of simultaneously attached cross-bridges in the force generating state. two processes are necessary for the force generation: firstly ca++ release from the sarcoplasmic reticulum to the sarcoplasm and the binding of ca++ by the troponin molecule and secondly the turnover of myosin-actin cross-bridges. these processes require energy in at least three different atpase reactions and can consequently be inhibited when atp hydrolysis is decreas ...20133964254
biochemistry of muscle fatigue.fatigue--or decrease in force generation--is a reduction of simultaneously attached cross-bridges in the force generating state. two processes are necessary for the force generation: firstly ca++ release from the sarcoplasmic reticulum to the sarcoplasm and the binding of ca++ by the troponin molecule and secondly the turnover of myosin-actin cross-bridges. these processes require energy in at least three different atpase reactions and can consequently be inhibited when atp hydrolysis is decreas ...20133964254
obsessions and compulsions in three kinds of headache sufferers: analysis of the maudsley questionnaire. 20143964178
effects of arterial ph and hco-3 concentration on hco-3 secretion in the isolated blood-perfused dog pancreas.we examined the effects of plasma ph and plasma hco-3 concentration on pancreatic hco-3 secretion in resting state and in stimulated state by secretin, pancreozymin or dopamine, using the isolated blood-perfused dog pancreas. secretin- or pancreozymin-induced hco-3 secretion was sensitive to changes in both plasma ph and hco-3 concentration. on the other hand, neither plasma ph nor plasma hco-3 concentration affected dopamine-induced hco-3 secretion and spontaneous hco-3 secretion. these results ...19863963941
the effect of needle stimulation of acupuncture loci tienshu (st-25) chung-wan (cv-12) on the immune response in sensitized mice against experimental cholera.the effects of stimulation of acupuncture loci from tien-shu (st-25) piercing through chung-wan (cv-12) on the leukocytes and immune response were assessed in mice (that is, the anatomical equivalent of these loci of human acupuncture points). the leukocyte count increased and reached its highest level two hours after needling, then restored to normal level 24 hours later both in normal mice and immunized mice. statistical analysis showed no significant variation on the lymphocyte/total leukocyt ...19863962918
burnley relatives' clinic.the organization of a clinic for relatives of geriatric patients is described, including a retrospective study of the reasons for referral to the clinic and a discussion of its value to patients, relatives and the geriatric team.20123962759
quantification of arterial stenoses by simultaneous measurement of blood pressure and blood velocity in the common femoral artery. 20143962454
in vitro production of anti-influenza virus antibody after simultaneous administration of h3n2 and h1n1 cold-adapted vaccines in seronegative children.sixteen doubly seronegative (h3n2 and h1n1) young children were recently enrolled in a study of live, attenuated cold-adapted influenza a vaccines. twelve children received simultaneously h3n2 and h1n1 live, attenuated influenza vaccine intranasally and four received saline as placebo controls. peripheral blood lymphocytes (pbl) were obtained sequentially from all children and the in vitro production of anti-influenza h3n2 and h1n1 antibody from unstimulated and influenza stimulated cells was me ...19863962451
[significance of atherosclerotic risk factors in the development of preatherosclerotic changes in the human aorta].a study of the effect of the main risk factors of atherosclerosis in coronary patients on the prevalence of lipoidosis and prelipid changes in the aortal intima showed a week interrelationship between the studied risk factors and prevalence of lipoidosis. a noticeable significant interrelationship of the prevalence of prelipid changes in the aortal intima, patient's age, the iri level and alpha-xc concentration in the blood plasma was established. an equation was described. a nomogram was presen ...19863961688
factors influencing prognosis in carcinoma of the stomach.prognostic factors were prospectively sought in a consecutive group of 223 patients with carcinoma of the stomach observed for a minimum of seven years. age, race and mode of presentation did not influence survival time. statistically improved seven year survival rates were observed in females (p less than 0.01) and patients with several features: symptoms lasting more than six months (p less than 0.01); absence of an abdominal mass (p less than 0.01); t1 versus t3 stage of disease (p less than ...20143961656
[unusual forms of chronic inflammatory diseases of the large intestine]. 20143961340
pricing life: a historical and sociological perspective. 20133960892
covalent binding of styrene oxide to amino acids, human serum proteins and hemoglobin. 19863960869
merger: means to meet your practice goals? 20133960542
merger: means to meet your practice goals? 20133960542
multinuclear approach to nuclear magnetic resonance investigations in tissue with heteronuclei: 14n, 35cl, 39k. 19863960139
how to establish official student chapters of aamd at colleges and universities. 20143959898
improvement in men inpatients in an alcoholism rehabilitation unit: a week-by-week comparison.the brief symptom inventory (bsi), a 53-item psychiatric symptom checklist, was administered to 57 alcoholic inpatients on days 2, 10, 18 and 26 of their 28-day stay in an alcoholism rehabilitation unit at a veterans administration hospital. the results of the test show a steady decline in the patients' psychiatric symptomatology from week 1 to week 4 with the most dramatic improvement evidenced between weeks 1 and 2.20133959565
improvement in men inpatients in an alcoholism rehabilitation unit: a week-by-week comparison.the brief symptom inventory (bsi), a 53-item psychiatric symptom checklist, was administered to 57 alcoholic inpatients on days 2, 10, 18 and 26 of their 28-day stay in an alcoholism rehabilitation unit at a veterans administration hospital. the results of the test show a steady decline in the patients' psychiatric symptomatology from week 1 to week 4 with the most dramatic improvement evidenced between weeks 1 and 2.20133959565
traumatic total hyphema in a patient with severe hemophilia.a 12-year-old hemophilic boy suffered from secondary glaucoma in his right eye due to total hyphema following trauma. an emergency operation was performed to evacuate the hyphema under a tight anti-hemophilic treatment. a careful postoperative treatment with factor viii concentrate, antiglaucomatous drugs and aminocaproic acid was administered. intraocular pressure returned to normal and remained so during the four months follow-up period. visual acuity returned to 6/9 and there was no rebleedin ...20143958875
persistence of cholera in the united states: isolation of vibrio cholerae o1 from a patient with diarrhea in maryland.a case of cholera was identified in baltimore county, md., in october 1984. the vibrio cholerae o1 isolate from the patient was hemolytic, biotype el tor, serotype inaba, and was toxigenic by the y-1 adrenal cell assay; on southern blot analysis, the strain had a unique hindiii restriction site in the cholera toxin gene identical to that of other u.s. v. cholerae o1 isolates. two days before he became ill, the patient had eaten meat from crabs harvested along the texas coast.19863958151
urinary cortisol in the assessment of pituitary-adrenal function: utility of 24-hour and spot determinations.to more conveniently assess dynamic changes in the biologically active fraction of cortisol, we measured cortisol in 1-h urine samples obtained from 0700-0800 and from 2200-2300 h. in 20 normal subjects, morning 1-h urinary cortisol levels were 78 +/- 36 ng/mg creatinine (mean +/- sd), whereas levels from 2200-2300 h were 22 +/- 12 ng/mg creatinine, demonstrating diurnal variability. in 14 patients with cushing's syndrome, mean morning urinary cortisol was elevated (207 +/- 176 ng/mg creatinine) ...19863958132
fractured odontoid with fractured superior articular process of the axis. report of three cases.we report three patients in whom a fractured odontoid process was associated with a fracture of the superior articular process of the second cervical vertebra. although there were no signs of neurological disorder, damage to the c1-c2 joint in all three patients made fusion necessary. forced lateral flexion is suggested as the possible mechanism of injury.20143957998
techniques for managing the self-study.accreditation is a status frequently sought by institutions and programs. it is also a process that includes a self-study, an on-site visit, and a survey report. the need for self-evaluation as part of the accreditation process is well documented. many institutions have difficulty initiating the activity of developing the self-study. this article attempts to provide assistance in preparing the self-study. it outlines the basic steps of accreditation and provides a checklist for accreditation act ...20143957781
practice standards and the standard of skill and care. 20143957757
isoeffect curves for radiation-induced myocardial damage. 19863957741
dosimetry of ct-guided volumetric ir-192 brain implant.over the past 2 years, an afterloading technique has been developed and refined to implant radioactive ir-192 sources into brain tumors. the implantation procedure integrates a stereotaxic system with computerized tomography (ct), which provides tumor position, volume, and guides the placement of catheters. a radiolucent ring-frame immobilizes the head as holes are made at 1 cm intervals with the aid of a template. catheters containing dummy sources 1 cm apart are then inserted to the desired de ...20143957734
[suitability of speech audiometry study procedures for current demands in clinical and general practice].the quality of the recorded audiometric test material (the "freiburg" and "marburg" language test) meets the high fidelity standards of the 1960's. in the light of current technology (digital technique, compact disc, etc.), the question arises whether speech-audiometry can still contribute to diagnosis, medico-legal assessment and fitting of hearing aids. results of the "freiburg" language test are presented, which analyse the comparability of the individual groups in quiet and in noisy surround ...20143957726
relationship between maternal vitamins b2 and b6 status and the levels of these vitamins in milk at different stages of lactation. a study in a low-income group of indian women.riboflavin and vitamin b6 status of mothers from a low-income group were assessed by erythrocyte glutathione reductase activation and erythrocyte aspartate aminotransferase activation tests respectively, at different stages of lactation. levels of these vitamins in milk were also measured. the majority of the women had biochemical evidence of vitamins b2 and b6 deficiency. there was a bizarre reduction in erythrocyte glutathione reductase activation from 6 to 30 d post partum. levels of riboflav ...19863957716
platelets, leucocytes and buffy layer vitamin c after surgery.the changes in buffy layer (bl) vitamin c concentration following surgical operations were studied in relation to changes in the leucocyte and platelet counts. it was found that the postoperative fall and subsequent changes in bl vitamin c concentration corresponded to changes in the platelet/leucocyte ratio (plr) in whole blood and consequently in the buffy layer preparations from which vitamin c concentrations were measured. the results of the study showed that the fall in bl vitamin c measure ...20143957709
hb m iwate [alpha (2)87his----tyr beta 2]: de novo mutation in an irish family. 20143957697
hemoglobin san diego/beta zero thalassemia in a greek adult.interaction of beta zero thalassemia with hb san diego [a high affinity hemoglobin variant, alpha 2 beta (2)109(g11)val----met] in a 29-year-old greek male is described. a marked polycythemia with low mch and mcv, but minor clinical problems were observed. functional properties of the isolated variant are described.20143957694
velopharyngeal insufficiency in children: the variable clinical presentation. 20143957645
treatment of chemical dependency: a new field for physicians. 20143957617
lice & scabies control. 20143957613
routine admission chest x-ray in the management of hospitalized patients. 20143957607
contrast, coagulation, and fibrinolysis.some adverse clinical effects of intravascular radiologic contrast agents have been attributed to their interference with the normal hemostatic processes. this study compares the effects of the low osmolality agents with those of the conventional agents by in vitro studies of platelet function, fibrin formation, and fibrinolytic activation. in various degrees, all the contrast agents studied inhibit platelet aggregation and fibrin formation but show virtually no direct activation of fibrinolysis ...20143957598
purification and characterization of vibrio cholerae non-o1 heat-stable enterotoxin.a toxin which causes rapid fluid accumulation in a suckling mouse assay and which was produced by vibrio cholerae non-o1 was investigated. the toxin was purified from the culture supernatant of v. cholerae non-o1 (strain a-5) by ammonium sulfate fractionation, hydroxyapatite treatment, ethanol extraction, column chromatographies on sp-sephadex c-50 and deae-sephadex a-25, and high-pressure liquid chromatography on a lichrosorb rp-8 column. about 1.4 x 10(5)-fold purification was achieved, with a ...19863957432
purification and partial characterization of a non-o1 vibrio cholerae hemolysin that cross-reacts with thermostable direct hemolysin of vibrio parahaemolyticus.a newly identified hemolysin (nag-rtdh), which is related to the thermostable direct hemolysin (vp-tdh) of vibrio parahaemolyticus produced by non-o1 vibrio cholerae, was studied. nag-rtdh was purified by successive column chromatographies on deae-cellulose and an immunoaffinity column coupled with anti-vp-tdh immunoglobulin. the molecular weight of nag-rtdh was estimated as 18,500, similar to that of vp-tdh, as judged by sodium dodecyl sulfate slab gel electrophoresis, but its charge or molecul ...19863957429
an analysis of class i antigens of man and other species by one-dimensional ief and immunoblotting.a procedure for the molecular identification of mhc class i products based on 1-d ief and subsequent immunoblotting is described. optimal conditions for 1-d ief, the electrophoretic transfer of proteins out of denaturing, nonionic detergent-containing gels to nitrocellulose, and the requisite antibodies, both polyclonal and monoclonal, for the visualization of class i heavy chains have been established. cross-reactivity of antibodies has enabled the biochemical analysis of class i heavy chains i ...19863957414
mental impairment in martin-bell syndrome is probably determined by interaction of several genes: simple explanation of phenotypic differences between unaffected and affected males with the same x chromosome.a family with martin-bell syndrome (mbs) is described with transmission of this x-linked trait by a normal male who manifested the fragile site at xq27. this family shows features apparently typical for all families with a normal male transmitter. the daughters of this male are mentally normal and their fragile site is difficult or impossible to detect but detection of the heterozygous genotype is much easier among the granddaughters. this can be explained by a model assuming that mental deficie ...20133957348
[determination of anionic surface-active substances in the blood serum by a colorimetric method]. 20143957060
proximal and distal changes in collagen content of peripheral nerve that follow transection and crush lesions.collagen content of rat sciatic nerve was measured 10 weeks after either nerve transection or nerve crush. nerve transection led to a significant increase in fascicular collagen in nerve segments 2.5 mm proximal and distal to the injury site. remote from the transection, fascicular collagen was also significantly increased, this effect being most marked distally. nerve crush by comparison resulted in only a small increase in fascicular collagen, significantly less than after transection. the gre ...19863956663
polypeptides during early conjugation in tetrahymena thermophila.as tetrahymena thermophila cells differentiate from their vegetative life cycle to sexual reproduction, their polypeptide pattern undergoes a series of changes. these changes have been traced in extracellular, cellular, and subcellular compartments. the first alteration is induced by the nutritional shift-down and results in stimulation of at least one ciliary polypeptide and affects a series of polypeptides from other compartments. the second alteration is induced by mixing starved cells of com ...20133956587
nadph/nadh-dependent cold-labile glutamate dehydrogenase in azospirillum brasilense. purification and properties.a cold-labile glutamate dehydrogenase (gdh, ec 1.4.1.3) has been purified to homogeneity from the crude extracts of azospirillum brasilense. the purified enzyme shows a dual coenzyme specificity, and both the nadph and nadh-dependent activities are equally cold-sensitive. the enzyme is highly specific for the substrates 2-oxoglutarate and glutamate. kinetic studies with gdh indicate that the enzyme is primarily designed to catalyse the reductive amination of 2-oxoglutarate. the nadp+-linked acti ...19863956501
cadmium acclimation and hormesis in fundulus heteroclitus during fin regeneration.we have previously demonstrated that exposure to cadmium at 0.1 and 0.5 mg/liter will retard the rate of fin regeneration in fundulus heteroclitus. since there is a body of literature indicating that preexposure to low levels of metals may increase tolerance during subsequent exposure, these experiments were designed to investigate the effects of preexposure to cadmium, using fin regeneration as the parameter of effect. fish were exposed for 1 week to 0, 0.01, or 0.05 mg/liter cd. following this ...20143956462
emotion socialization and expressive development in preterm and full-term infants.the expressive behaviors of full-term and preterm infants and their mothers were examined during face-to-face interaction when the infants were approximately 2 1/2, 5, and 7 1/2 months old. videotapes of the sessions were coded on a second-to-second basis using izard's discrete emotion coding system. overall, infants showed a linear increase in positive effect, especially interest and joy, and a corresponding decrease in negative affect, especially pain and knit brow, with age; decrease in negat ...20093956316
vitellogenin levels in male and female rainbow trout (salmo gairdneri richardson) at various stages of the reproductive cycle.the immunoassayable vitellogenin (vtg) in plasma from male rainbow trout had the same molecular weight as authentic vtg from female fish. the vtg level in male trout was low (usually nanograms, occasionally up to a few micrograms, per ml) and did not correlate with the stage of sexual maturity. the plasma vtg level of female trout that were two years from first spawning was 200-fold higher than males of the same strain and age. the plasma vtg level of female rainbow trout rose approximately a mi ...20143956165
[determination of the severity of aortic stenosis using a one-dimensional ultrasonic method]. 20143955612
isolation and characterization of two sialyloligosaccharides containing n-acetyllactosamine from pregnancy urine. 19863955566
lack of evidence of hepatitis d (delta) infection in newfoundland and labrador.epidemiologic knowledge of hepatitis d virus (hdv) infection is limited. a seroepidemiologic study was undertaken to determine the prevalence of the infection in newfoundland and labrador. between october 1983 and october 1985 over 200 people were recognized through routine serodiagnosis and screening as having hepatitis b seromarkers. a total of 223 serum samples from 186 of these people were tested for anti-hdv. the subjects were mainly asymptomatic carriers of hepatitis b surface antigen or p ...19863955485
lack of evidence of hepatitis d (delta) infection in newfoundland and labrador.epidemiologic knowledge of hepatitis d virus (hdv) infection is limited. a seroepidemiologic study was undertaken to determine the prevalence of the infection in newfoundland and labrador. between october 1983 and october 1985 over 200 people were recognized through routine serodiagnosis and screening as having hepatitis b seromarkers. a total of 223 serum samples from 186 of these people were tested for anti-hdv. the subjects were mainly asymptomatic carriers of hepatitis b surface antigen or p ...19863955485
image reconstruction using electron micrographs of insect flight muscle. use of thick transverse sections to supplement data from tilted thin longitudinal sections.three-dimensional reconstruction using electron micrographs of thin sections is a powerful technique for determining cross-bridge structure. tilt restrictions in the electron microscope prevent data collection beyond tilt angles of 60 degrees, giving rise to a "missing cone" of transform data. we show here how much of this data can be obtained using micrographs of thick transverse sections, and the effect this data has on reconstructed images of the insect flight muscle myac layer. as a byproduc ...20143955176
hypomagnesemia in digitalized patients. 20103954538
topological shifts of sudanophilic bodies in ageing male gonad.the topological index of sudanophilic bodies was determined in 69 testicles of men aged from 16 to 87 years (mean age 53.5 years) divided into 3 age groups, from 16 to 40 years, from 41 to 60 years, and from 61 to 87 years. a significant fall of sudanophilia was demonstrated in leydig cells from 17.6% in young men to 11.15% in middle-aged men, and with a further non-significant fall to 8.2% in old men. since this index demonstrates relative changes of sudanophilia, a significant increase was fou ...20103954088
iron losses in sweat.the losses of iron in whole body cell-free sweat were determined in eleven healthy men. a new experimental design was used with a very careful cleaning procedure of the skin and repeated consecutive sampling periods of sweat in a sauna. the purpose was to achieve a steady state of sweat iron losses with minimal influence from iron originating from desquamated cells and iron contaminating the skin. a steady state was reached in the third sauna period (second sweat sampling period). iron loss was ...20143953482
[intracranial hypertension in the acute stage of a stroke (spinal fluid dynamic and computer-tomographic studies)].the given study aimed to answer the question about the realization in clinical practice of the possibility of the timely identification of the degree of intracranial hypertension in patients with cerebral stroke under continuous monitoring of the intracranial volume/pressure ratios by means of examination of csf changes and ct of the head. on the basis of an analysis of the interrelationship between the severity of neurologic deficit, findings of ct of the head and the results of examination of ...20143953189
interactions of vasoactive intestinal polypeptide and cholecystokinin octapeptide on the control of gallbladder contraction.the gallbladder is supplied by three types of vagal fibers: cholinergic, cholecystokinin (cck)-ergic, and vasoactive intestinal polypeptide (vip)-ergic. most previous studies on the interaction of vip and cck on gallbladder contraction have been in vitro. in this study we evaluate this interaction more fully in vivo using six dogs with chronic bile fistula. dose-response curves were constructed to cck-8 alone and to vip alone. the effect of graded doses of vip on maximal response to cck-8 was al ...19863952671
interactions of vasoactive intestinal polypeptide and cholecystokinin octapeptide on the control of gallbladder contraction.the gallbladder is supplied by three types of vagal fibers: cholinergic, cholecystokinin (cck)-ergic, and vasoactive intestinal polypeptide (vip)-ergic. most previous studies on the interaction of vip and cck on gallbladder contraction have been in vitro. in this study we evaluate this interaction more fully in vivo using six dogs with chronic bile fistula. dose-response curves were constructed to cck-8 alone and to vip alone. the effect of graded doses of vip on maximal response to cck-8 was al ...19863952671
effects of dietary fat on mammary development relative to age and hormones in balb/c mice.earlier studies reported that mammary ducts grew faster if the 10% fat in the diet was composed of oils containing polyunsaturated fatty acids (corn oil: co) compared to hydrogenated cottonseed oil (hcto), which is devoid of such fatty acids. these experiments were primarily carried out in immature mice and left unanswered questions regarding the effects of dietary fats on more differentiated stages of mammary development. the use of transplanted ducts permitted the study of mammary growth rates ...19863952083
spinal cord injury associated with all-terrain vehicle accidents.five instances of three-wheeler, all-terrain vehicle accidents resulting in spinal cord injury are presented. age range of victims was from 7 to 18 years. of the five cases of spinal cord injury, three resulted in quadriplegia and two in paraplegia. reports of all-terrain vehicle accidents in childhood from the us consumer product safety committee are also reviewed. concerns are raised about the need for further data gathering about instances and types of injuries from these types of vehicles an ...20143951908
use of epidural opioid 'blockade' as an adjuvant diagnostic procedure. 20133951881
use of epidural opioid 'blockade' as an adjuvant diagnostic procedure. 20133951881
differential pencil beam dose computation model for photons.differential pencil beam (dpb) is defined as the dose distribution relative to the position of the first collision, per unit collision density, for a monoenergetic pencil beam of photons in an infinite homogeneous medium of unit density. we have generated dpb dose distribution tables for a number of photon energies in water using the monte carlo method. the three-dimensional (3d) nature of the transport of photons and electrons is automatically incorporated in dpb dose distributions. dose is com ...20143951411
[economical resection of the stomach in cancer]. 20133951154
infection by choleraphage phi 138: bacteriophage dna and replicative intermediates.choleraphage phi 138 contains a linear, double-stranded, circularly permuted dna molecule of 30 x 10(6) daltons or 45 kilobase pairs. upon infection, the host dna is degraded, and synthesis of phage-specific dna is detectable 20 min after infection. the phage utilizes primarily the host dna degradation products for its own dna synthesis. a physical map of phi 138 dna was constructed with the restriction endonucleases bg/ii, hindiii, and psti. a concatemeric replicative dna intermediate equivalen ...19863951021
competencies for mainstreaming secondary level learning disabled students. 20143950520
levels and patterns of intellectual functioning among ld college students: clinical and educational implications. 20143950517
the role of motivation and pedagogy on the generalization of cognitive strategy training. 20143950516
reconciling standards and individual differences. 20143950515
oral malignant melanoma (a case report and review of literature).oral malignant melanoma is rare and has a poor prognosis. we report a case of melanoma of the lower alveolus with rapid spread to the cervical lymph nodes and breast. metastasis was diagnosed by fine needle aspiration cytology. the literature on oral melanoma is also reviewed.20143950509
oto-admittance measurements in the diagnosis of otosclerosis.theoretical considerations show that admittance measurements are likely to be more sensitive in differentiating between middle-ear pathologies than compliance measurements. thirty-five ears in 20 patients with clinical otosclerosis were studied to assess the usefulness of admittance measurements in contributing to diagnosis.20143950475
clonal spread of multiply resistant strains of vibrio cholerae o1 in somalia. 19863950453
the impact of physico-chemical stress on the toxigenicity of vibrio cholerae.the expression of toxigenicity by vibrio cholerae, before and after exposure to various conditions of salinity, ph and cation composition and concentration, has been measured. exposure to these conditions did not select for hyper- or hypo-toxigenic strains. this suggests that toxigenic v. cholerae o1 are unlikely to lose their toxigenicity when exposed to environmental stress and that v. cholerae toxin production is not a response to the stresses included in this study. these results are consist ...19863950396
effect of a reca mutation on cholera toxin gene amplification and deletion events.the cholera toxin operon (ctxab) is located on a 7-kilobase pair variable genetic element which undergoes genetic duplication and amplification events in vibrio cholerae. amplification of the ctx genetic element was investigated by substituting the resident ctx loci of two v. cholerae strains with a dna fragment encoding resistance to kanamycin. although these strains were not normally resistant to greater than 150 micrograms of kanamycin per ml, spontaneous derivatives could be obtained that gr ...19863949714
antepartum fetal heart rate recording and subsequent fast transmission by a distributed microprocessor-based dedicated system.fetal heart rate monitoring in high-risk pregnancies can require admission to hospital over prolonged periods, or the even less satisfactory alternative of routine weekly or sporadic outpatient monitoring. we have developed a digital system for distant fetal heart rate recording with the facility of later rapid transmission by telephone into the hospital. a completed half-hour recording is transmitted to the central computer and permanently stored in less than 30 s, then immediately displayed fo ...20123949420
is peptic ulcer a prostaglandin deficiency disease? 20133949334
growth hormone modulates serum cholinesterase.adult male rats have lower serum cholinesterase activity levels than adult female rats and hypophysectomized male rats have higher activity levels than sham-operated males (similar to control females). gh administered to hypophysectomized male rats abolishes the effect of hypophysectomy on serum cholinesterase. adult male rats treated neonatally with monosodium l-glutamate to induce arcuate nucleus lesions of the hypothalamus have higher serum cholinesterase activities and decreased serum gh con ...19863948777
sequential monitoring of peripheral blood lymphocyte subsets in rats.the methodology of enumeration of t cell subsets in humans is well established and has widespread clinical application. sequential monitoring of lymphocyte subsets in small animals requires a consistent and reliable methodology for staining and enumerating lymphocyte populations. the optimal conditions for enumerating subclasses of rat peripheral blood lymphocytes with the spectrum iii flow cytometer are described. the sources of biological variation and technical error that were considered in o ...19863948606
[the truth or a "merciful" lie in communicating the basic diagnosis to patients with malignant tumors?]. 20143948222
retention of products of conception after therapeutic abortion. 20143948065
neurotensin excites neurons in the arcuate nucleus of the rat hypothalamus in vitro.the effects of neurotensin (nt) on 41 spontaneously active neurons in the rat hypothalamic arcuate nucleus (arc) were determined using an in vitro brain slice technique. addition of nt (1 microm to 10 nm) to the perifusing medium allowed the action of known concentrations of nt to be examined. concentrations of peptide greater than 10 nm evoked excessive depolarization of sensitive neurons resulting in long periods of postexcitatory inhibition. at 10 nm, nt evoked reversible and repeatable excit ...19863947977
comparison of radiosensitivities of human autologous normal and neoplastic thyroid epithelial cells.studies were conducted to examine differences between the radiosensitivities of normal and neoplastic epithelial cells of the human thyroid. freshly excised thyroid tissues from the tumours of eight patients with papillary carcinoma (pc) and five with follicular adenoma (fa) were cultured in vitro separately from normal thyroid tissue obtained from the surgical margins of the same patients. plating efficiency of unirradiated control tissue was lower, on average for tumour tissue compared with no ...19863947820
the role of allergy in otitis media with effusion. 20133947468
serum formate concentrations in methanol intoxication as a criterion for hemodialysis.to evaluate the utility of serum formate concentrations, four patients were studied after ingestion of a methanolic copying fluid. all patients were initially intoxicated. twelve to twenty-four hours later, signs and symptoms included nausea, abdominal pain, hypokalemia, acidosis (three patients), and pathologic ocular findings (two patients). all patients were treated with ethanol and folate. the two patients with ocular signs and acidosis had high serum formate concentrations (75 and 55 mg/dl, ...20133946945
serum formate concentrations in methanol intoxication as a criterion for hemodialysis.to evaluate the utility of serum formate concentrations, four patients were studied after ingestion of a methanolic copying fluid. all patients were initially intoxicated. twelve to twenty-four hours later, signs and symptoms included nausea, abdominal pain, hypokalemia, acidosis (three patients), and pathologic ocular findings (two patients). all patients were treated with ethanol and folate. the two patients with ocular signs and acidosis had high serum formate concentrations (75 and 55 mg/dl, ...20133946945
impact of epidemic cholera in a previously uninfected island population: evaluation of a new seroepidemiologic method.during an investigation of a 1982 cholera outbreak in truk, an area without endemic cholera, 254 post-outbreak serum specimens were collected from ill and well inhabitants of a single island. these were compared with 57 specimens collected in truk in 1964, when heat-labile toxin-producing enterotoxigenic escherichia coli was presumably endemic but cholera did not exist. the serum was tested for vibriocidal antibody and antitoxic antibodies to cholera toxin and heat-labile toxin and the ratio of ...19863946388
overdose with baclofen. 20143945841
overdose with baclofen. 20143945841
virchow-robin space: a path of spread in neurosarcoidosis.three cases of documented sarcoid meningoencephalitis were reviewed. computed tomography (ct) showed enhancing, perivascular, linear, and nodular areas along the subarachnoid space, extending deep into the white matter. in one case the perivascular granulomatous infiltration, which caused small vessel periangiitis, gave rise to a ct pattern closely resembling that of arteriovenous malformation or infarction with gyral enhancement. this infiltrative pattern might be seen in other chronic meningea ...20143945745
vasopressin peptide (ddavp) may narrow the focus of attention in normal elderly.administration of ddavp (1 desamino-8-d-arginine vasopressin), a form of vasopressin with little pressor action, has been shown to improve cognitive performance in the elderly. it remains unclear whether memory processes are specifically influenced or more general processes are altered. fifteen elderly subjects performed a central mental arithmetic task and a peripheral choice reaction time task in ddavp and control conditions. ddavp slowed reaction times to peripheral lights but did not alter a ...20143945698
pitfalls in percutaneous filling of the tissue expander. 20143945697
modification of excitation and inhibition evoked in dentate gyrus by perforant path stimulation: effects of aminophylline and kindling.rats were implanted with chronic electrodes to stimulate the perforant path and record the elicited monosynaptic evoked potentials from the dentate gyrus of the hippocampal formation. dentate responses were examined in awake and anesthetized animals after exposure to saline and aminophylline (100 mg/kg, ip). in the awake animal, aminophylline treatment did not significantly alter the threshold or elicited amplitude of either the excitatory post-synaptic potential (epsp) or the population spike ( ...19863945669
modification of excitation and inhibition evoked in dentate gyrus by perforant path stimulation: effects of aminophylline and kindling.rats were implanted with chronic electrodes to stimulate the perforant path and record the elicited monosynaptic evoked potentials from the dentate gyrus of the hippocampal formation. dentate responses were examined in awake and anesthetized animals after exposure to saline and aminophylline (100 mg/kg, ip). in the awake animal, aminophylline treatment did not significantly alter the threshold or elicited amplitude of either the excitatory post-synaptic potential (epsp) or the population spike ( ...19863945669
malaria--mitogens or super antigens? 20143945342
reliability and stability of the thymidine labeling index of breast carcinoma.we have approached the question of the reliability of the thymidine labeling index (tli) of breast carcinoma by comparing paired samples. because the distribution of the tli is approximately lognormal, comparisons were made after transformation to the natural logarithm. for 38 paired samples from the primary carcinoma (biopsy versus residual tumor in mastectomy specimen), r, 0.89, p less than 0.0001. for 68 primary carcinomas versus their axillary metastases, r, 0.90, p less than 0.0001. substan ...20143945050
the crutch-crotch aid in radical retropubic prostatectomy.adequate exposure of the urethra during radical retropubic prostatectomy is difficult at times. a crutch placed strategically in the perineum has been used successfully to improve exposure in 21 patients.20143944863
metabolic rate alterations in early excision and grafting versus conservative treatment.this study was done to determine whether early massive excision and grafting would decrease the hypermetabolic response that characterizes burn injury. thirteen consecutively admitted adult males with burns over more than 45% of the total body surface area (tbsa) were randomly assigned to one of two treatment groups. one group was treated by excising the burn within 72 hours of injury and grafting with autograft overlaid with cadaveric allograft or cadaveric allograft alone depending on availabl ...20143944837
late resistance to corticosteroids in nephrotic syndrome.corticosteroid resistance appeared late in the course of relapsing nephrotic syndrome in 12 patients who previously had steroid-sensitive relapses for 0.8 to 13 years. in 11 patients, renal histology performed earlier in the course of the disease showed minimal change in eight, mesangial proliferative glomerulonephritis (mespgn) in two, and focal segmental glomerulosclerosis (fsgs) in one. renal biopsy in another patient and a repeat procedure in four of eight patients who initially showed minim ...20143944696
influence of gentle birth delivery procedures and other perinatal circumstances on infant temperament: developmental and social implications. 20143944678
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