Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [the analysis of strain and displacement, produced by the kloehn type face bow in the dry skull of the macaca irus (author's transl)]. | 1976 | 829783 | |
| effects of extraoral forces in the dentofacial complex of the macaca irus. | 1975 | 829781 | |
| [experimental gingivitis by feeding soft food containing sucrose. repeated observation in a macaca irus monkey (author's transl)]. | 1976 | 829780 | |
| studies on pancreatic islet accumulation and cytotoxicity of n-nitrosomethylurea in the cynomolgus monkey. | 1976 | 828134 | |
| differences in vitro between cells derived from periodontal ligament and skin of macaca irus. | 1976 | 828044 | |
| comparative study of the banding patterns of the chromosomes of cercopithecidae. i. subfamily papinae: macaca fascicularis and papio sphinx. | the diploid number of macaca fascicularis and papio sphinx is 42. all chromosomes are biarmed. using g-banding techniques, the complements of these two species have been compared. the topography of the bands is identical in all but one chromosome pair, showing a small pericentric inversion. the results indicate the existence of an extreme conservation in the arrangement of the genetic material and that changes at the gene level may have contributed to speciation in the papinae. | 1976 | 827484 |
| chemical composition of cynomolgus monkey milk. | milk samples from eight cynomolgus monkeys whose lactation period ranged 44-119 days were investigated for their gross chemical composition such as total solids, crude protein, lipids, lactose and ash. nitrogen distribution, compositions of fatty acids, amino acids and triglycerides as well as major minerals were also determined. these analytical data were compared with those reported for man, simian and cow, and cynomolgus monkey milk was found to have close similarities to human milk. | 1976 | 827449 |
| [antifertility effect of an active immunization of monkeys with human pregnancy-specific beta 1-glycoprotein (sp1) (author's transl)]. | fertile female cynomolgus monkeys (macaca fascicularis) were actively immunized against human pregnancy-specific beta 1-glycoprotein (sp1). native sp1 as well as chemically modified derivatives of sp1 served as antigens. the effect of the immunization on reproduction in these animals was investigated. the immunized monkeys showed a significant reduction in fertility: the conception rate in these animals was only slightly reduced when compared with the controls; but in the immunized monkeys pregn ... | 1976 | 827272 |
| influence of cholinergic receptor blockade on drug-induced prolactin release in the monkey. | the influence of varying doses of perphenazine, thyrotropin-releasing hormone (trh) and serotonin on prolactin release was examined in two species of monkeys: rhesus (macaca mulatta) and crab-eating (macaca fascicularis). the intravenous administration of 0.33 mg/kg body weight of perphenazine or 1.0 mug/kg body weight of trh gave a greater release of prolactin than higher doses of perphenazine (1.0 mg/kg) or trh) (3.4 mug/kg), respectively. prolactin release induced by serotonin at doses of 1, ... | 1976 | 826472 |
| blood groups of bonnet macaques (macaca radiata), with a brief introduction to seroprimatology. | the human-type a-b-o blood groups of 52 bonnet macaques (macaca radiata) were determined. application of method of population genetics indicated the gene frequences to be 0 = 0.173, a = 0.480 and b = 0.347. cross testing of sera and red cells of the bonnet macaques revealed two blood-type-specific isoagglutinins, one of them strong enough for use as a blood typing reagent. no blood group polymorphism was revealed by testing bonnet macaque red cells with isoantisera produced in rhesus monkeys (m. ... | 1976 | 826172 |
| protrusions of the inner wall of schlemm's canal. | large specific protrusions of the trabecular meshwork into schlemm's canal (hernias) have been suggested to be the main drainage routes for aqueous humor, similar to the function of the arachnoid villi in draining the cerebrospinal fluid. my quantitative study in cynomolgus monkeys does not support such a hypothesis. the drainage routes of the aqueous humor, evaluated from the number and sizes of the pores observed by scanning electron microscopy, were as common through the hernias as through ot ... | 1976 | 826163 |
| effect of chemical modifications on the metabolic transformation of prostaglandins. | the metabolism of three analogues of pgf2alpha was studied in the cynomolgus monkey and in the human, viz., 15-methyl-pgf2alpha, 16,16-dimethyl pgf2alpha, and 17-phenyl-18,19,20-trinor-pgf2alpha. the half-lives of the three compounds in the human circulation was considerably longer than that of pgf2alpha. the dehydrogenation of the secondary alcohol group at c-15 was completely blocked in the two first-mentioned compounds. these were degraded mainly by beta-oxidation, and their main metabolites, ... | 1976 | 826142 |
| studies on the treponema pallidum immobilizing activity in normal human serum. 5. on the protective role against syphilis. | it was shown that t. pallidum immobilized in vitro by normal serum had lost its infectivity in rabbits. this finding suggested that the immobilizing activity of normal serum might play a role in the natural resistance of man against infections with t. pallidum. however, the results of serological studies of acquired early syphilis in man and of experimental syphilis in cynomolgus monkeys did not present evidence that the immobilizing activity of normal serum protected against syphilis infection. | 1976 | 826114 |
| an outbreak of epistaxis in cynomolgus monkeys (macaca fascicularis). | 1976 | 826008 | |
| initial colonization of teeth in monkeys as related to diet. | the initial phases of plaque development on nonretentive tooth surfaces were studied bacteriologically in macaca irus monkeys fed by stomach tube and provided with various oral supplements. except for the oral implantation of streptococcus mutans in some of the animals, the oral flora was not changed prior to the studies. dental plaque was allowed to develop on initially cleaned tooth surfaces for 3 to 5 h. plaque samples were collected and cultured on a number of selective and nonselective agar ... | 1976 | 825462 |
| oral glucose tolerance test in the cynomolgus monkey (macaca fascicularis). | the glucose tolerance test was simplified so that it could be performed on more than one cynomolgus monkey (macaca fascicularis) at a time. glucose was administered orally in a dose of 2 g/kg body weight as a 50% aqueous solution, and blood samples were taken just before and 30 minutes and 150 minutes after glucose administration. the simplified test was conducted on a total of 93 cynomolgus monkeys. glucose tolerance curves obtained by this method were classified into three patterns with regard ... | 1976 | 824499 |
| priming of macaca cynomolgus philippinensis with purified antigen of brucella melitensis before injection of rev. i vaccine. | in experiments designed for study of bacteremia and serologic response of macaca cynomolgus philippinensis to vaccination with a soluble antigen (fraction i) of brucella melitensis and the live rev. i vaccine strain, fraction i and rev. i were administered both four weeks apart and simultaneously. one of three monkeys given the vaccines four weeks apart and two of three monkeys vaccinated with fraction i and rev. i in a single injection developed transient bacteremia, as shown by blood cultures. ... | 1976 | 824373 |
| effects of paracentesis on the blood-aqueous barrier: a light and electron microscopic study on cynomolgus monkey. | the effects of paracentesis on the blood-aqueous barrier of cynomolgus monekeys were studied by light and electron microscopy. the following regions of the eye were examined: ciliary body, iris, schlemm's canal, juxtacanalicular connective tissue, and trabecular meshwork. prominent structural alterations were seen in the ciliary epithelium at the anterior portion of the pars plicata, but the epithelium at the posterior portion of the pars plicata and at the pars plana appeared less disrupted. pl ... | 1976 | 824223 |
| loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey. | an ab-interno goniotomy-like operation for disinserting the ciliary muscle from the scleral spur in cynomolgus monkeys is described. following postoperative miotic and corticosteroid treatment, the eyes did well clinically and the muscle reattached to the sclera posterior to the spur. outflow facility and intraocular pressure were mildly reduced. there was drainage of aqueous humor via the conventional outflow routes, and blood flow to the ciliary body. the outflow facility increasing effect of ... | 1976 | 824222 |
| histochemical studies on beta-glucuronidase activity in developing teeth and bone of rat and macaque monkey. | the enzyme beta-glucuronidase (e.c. 3.2.1.31.) has been studied in developing teeth and bone of sprague-dawley rats and macaque monkeys (macaca irus) by means of histochemistry using naphthol-as-bi-beta-d-glucuronide as substrate and hexazotized pararosanilin as coupling reagent. since beta-glucuronidase is sensitive to fixatives a freeze-sectioning technique has been used which made it possible to section highly mineralized tissues without previous fixation and decalcification. in the bone enzy ... | 1975 | 823790 |
| caesarean section in the java monkey (macaca irus)--a case report. | 1976 | 823378 | |
| effect of malnutrition on cortisol-binding protein in the lens of cynomolgus monkeys. | a cortisol-binding protein exists in the lens of cynomolgus monkeys as in other species. the cortisol-binding capacity decreased markedly with a diet either moderately or severely depleted of protein, even if the diet was later changed to a normal diet during infancy. this suggests that malnutrition may cause insufficient synthesis of the important factors controlling the inactivation of steroid hormone in the lens. | 1976 | 823312 |
| influence of cataleptoid anaesthetic agents on the intraocular pressure in monkeys (macaca fascicularis). | trained monkeys which allowed a tonometry while conscious were used to test the influence of cataleptoid anaesthetics on intraocular pressure (iop). the drugs were injected intramuscularly in two dosages: with the lower dose (dt) it became just possible to perform a tonometry in untrained monkeys. the second dose (ds) induced surgical anaesthesia. the drugs used were: phencyclidine, dt: 0.6-0.7 mg/kg, ds: 1.2-1.4 mg/kg. ketamine, dt: 4-6 mg/kg, ds: 25 mg/kg. ci-744, a combination of a pure catal ... | 1976 | 822686 |
| histochemical and biochemical properties of the labial and palatine glands and their secretions in the macaca irus and cercopithecus aethiops monkeys. | the increasing use of non-human primates in experimental studies in dentistry demands detailed knowledge of their basic oral biology. the labial and palatine glands and their secretory products were compared in two commonly used monkey species. the mucous cells of both gland types appeared to elaborate sulphated muco-substances and the serous demilunes of the labial glands neutral mucosubstances. the secretions of these glands, as obtained by in vitro cultivation of glandular tissue were subject ... | 1976 | 822685 |
| disynaptic inhibition of spinal motoneurones from the motor cortex in the monkey. | 1. the neuronal mechanism of disynaptic inhibition of spinal motoneurones by the corticospinal tract was investigated in macaca irus. surface stimulation or weak intracortical stimulation was used in order to evoke the inhibition. intracellular records were taken from motoneurones in lumbar segments. 2. both the disynaptic i.p.s.p.s evoked from group ia afferents and the disynaptic i.p.s.p.s evoked from corticospinal fibres were found to be depressed by conditioning stimulation of motor axons to ... | 1976 | 822152 |
| identification, classification and anatomical segregation of cells with x-like and y-like properties in the lateral geniculate nucleus of old-world primates. | 1. all the cells (158) that we studied in the lateral geniculate nuclei of macaca nemestrina and macaca irus could be distinguished as either x-like or y-like on the basis of their responses to tests developed to classify cat retinal and lateral geniculate nucleus cells. these tests include responses to stationary spots, fast moving wands and moving gratings. 2. response latencies to electrical stimulation of the optic chiasm were determined for 130 cells; no x-like cell showed a latency shorter ... | 1976 | 822151 |
| metabolism of 16,16-dimethyl-prostaglandin f2alpha in the cynomolgus monkey and the human female. | 1976 | 821483 | |
| proline-rich proteins in membranes and contents of monkey (macaca irus and cercopithecus aethiops) parotid zymogen granules. | 1976 | 821460 | |
| effect of bran and cholestyramine on plasma lipids in monkeys. | semipurified diets whose cholesterol content varied from 34 to 120 mg/100 kcal were given to adult female cynomolgus monkeys (macaca fascicularis) for 9 months. the intake of dietary fiber was increased through the addition of wheat, rice, or soya bran; 5% cholestyramine was given to one group of monkeys. none of the brans reduced plasma levels of cholesterol, whereas cholestyramine produced marked hypocholesterolemic effects. triglyceride levels increased with higher cholesterol intake, but no ... | 1976 | 821335 |
| applanation tonometry in the conscious cynomolgus monkey (macaca fascicularis). | four monkeys (macaca fascicularis) were trained to tolerate applanation tonometry while fully conscious. the tonometer used was the draeger tonometer with an applanation area of 3.06 diameter, but with a reduced application surface (4 mm instead of 6.8 mm diameter). the reduction did not change the calibration and is applicable in this monkey species without any correction factor. the mean intraocular pressure determined was 19.12 mmhg. | 1976 | 821306 |
| [surface structure of the lips and tactile hairs of cynomolgus monkeys. scanning electron microscopic studies on the transitional part between the skin and mucosa 1]. | 1976 | 821303 | |
| [nursing procedures for cynomolgus monkey infants (author's transl)]. | this paper describes the results of the artificial nursing of 8 infant cynomolgus monkeys (macaca fascicularis) weighing 230-350 g at birth. the infants were separated from their mothers just after or 2 days after birth and were kept in a specially deviced small cage (photo 1 & 2). they were fed on 6.4-16.6% solution of a commercially available powdered milk for the human baby. apple juice also was given to them from the 3rd or 4th week on. in about the 6th week, the infants received solid foods ... | 1976 | 820560 |
| responses of subthalamic and pallidal neurons to striatal stimulation: an extracellular study on awake monkeys. | the unitary activity of subthalamic neurons (corpus luysii) and of gp neurons was recorded extracellularly on awake monkeys (macaca cynomolgus). striatal stimulation induces in subthalamic (sth) neurons a short latency spike discharge (10-15 msec) followed by a long lasting depression of the spontaneous activity. as, according to anatomical studies, the subthalamic nucleus is principally connected to the globus pallidus (gp), electrophysiological relations between striatal and gp neurons and bet ... | 1976 | 820409 |
| evaluation and re-evaluation of genetic radiation hazards in man. ii. the arm number hypothesis and the induction of reciprocal translocations in man. | the arm number hypothesis proposed by brewen and collagues in 1973 has been examined in the light of information thus far available from mammalian studies. in experiments with peripheral blood lymphocytes (radiation in vitro), a linear relationship between dicentric yield and the effective chromosome arm number of the species was obtained in the mouse, chinese hamster, goat, sheep, pig, wallaby and man. however, the data are not consistent with such a relationship in several primate species (ma ... | 1976 | 819823 |
| residual pilocarpine effects on outflow facility after ciliary muscle disinsertion in the synomolgus monkey. | outflow facility responses to pilocarpine were determined in ten cynomolgus monkey eyes after disinsertion of the ciliary muscle from the scleral spur. the effect of large intravenous dose given on one occasion was compared to the effect of intense topical treatment for 18 to 24 hours on another occasion. the effect of the two modes of treatment differed from eye to eye, but were similar in the individual eye. in some eyes facility rose while in others it fell. the average effect of both treatme ... | 1976 | 819392 |
| the effect of entrapment in liposomes on the in vivo distribution of [3h]methotrexate in a primate. | entrapment of methotrexate (mtx) plus [3',5', 9(n)-3h]methotrexate into positively charged liposomes greatly alters the subsequent distribution of [3h]mtx in a cynomologous monkey (macaca irus) after a single i.v. injection ([3h]mtx; refers to total radioactivity derived from purified [3h]mtx). when [3h]mtx is incorporated into small, sonically disrupted liposomes, the level of the entrapped [3h]mtx in the total plasma volume was still 50% of the total injected dose after 4 hr, which is 100 time ... | 1976 | 819137 |
| proliferative epithelial lesions of the urinary bladder in cynomolgus monkeys (macaca fascicularis) infected with schistosoma intercalatum. | five cynomolgus monkeys (macaca fascicularis) were infected with schistosoma intercalatum, a helminth that is morphologically similar to schistosoma haematobium. infections were readily established and remained active until the monkeys were sacrificed 21 to 84 weeks after exposure. although the schistosomes were located predominantly in mesenteric and hepatic portal venules, schistosome eggs were found in the bladders of 3 monkeys. nodules of atypical epithelial cells interpreted as superficiall ... | 1976 | 819136 |
| immunoglobulins a, g, and m in serum and in some secretions of monkeys (macaca fascicularis syn. irus). | the purpose of this investigation was to study the distribution and levels of the following immunoglobulins, iga, igg, and igm ,in sera and in some secretions of monkeys (m. fascicularis). igg, iga, and igm were isolated from monkey serum and secretory iga was separated from monkey milk by combined gel filtration and ion-exchange chromatography. these pure preparations served as standards to quantitate immunoglobulins in sera and secretions by single radial immunodiffusion. antisera were raised ... | 1976 | 818024 |
| aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta. | the interrelationships between hypertension and atherosclerosis were investigated in a subhuman primate model (cynomolgus monkey) with hypertension produced by surgically coarcting the miathoracic aorta. the hypertensive coarcted monkey fed a low cholesterol diet for 6 months did not develop complicating atherosclerosis but did develop focal intimal lesions as well as marked thickening of the musculoelastic media of both the large and small arteries. fibrocellular thickening of the intima and me ... | 1976 | 817849 |
| immunization of macaca fascicularis (macaca irus) monkeys with streptococcus mutans: specificity of antibody responses in saliva. | m fascicularis monkeys were immunized subcutaneously in the vicinity of the major salivary glands and by retrograde infusion into the parotid duct, with a vaccine containing formalin-killed s mutans strain 6715 cells and culture-fluid antigens. indirect immunofluorescent staining was used to titrate and classify antibodies. subcutaneous immunization induced only a serum response, whereas intraductal infusion stimulated both an iga antibody response in the parotid fluid and a serum response. immu ... | 1976 | 816835 |
| thalamic projections from the precentral motor cortex in macaca fascicularis. | radioactive amino acids were injected into area 4 in 7 monkeys (macaca fascicularis). ipsilateral corticothalamic projections were traced to olszewski's nucleus ventralis lateralis pars oralis and pars medialis, the nucleus ventralis posterior lateralis pars oralis, the nucleus ventralis posterior medialis and inferior and to the nucleus reticularis. some fibers appeared to terminate in the ipsilateral nucleus ventralis lateralis pars caudalis, the nucleus lateralis posterior and the nucleus sub ... | 1976 | 816421 |
| experimental dirofilariasis in macaques. iii. susceptibility and host responses to dirofilaria tenuis of raccoons. | in this third of a series of studies on experimental dirofilariasis in primate hosts, 3 macaca cynomolgus, 6 m. speciosa, and 2 m. mulatta were inoculated with infective larvae of dirofilaria tenuis, a parasite of the raccoon, and were killed at periods ranging from 2 weeks to 13 months of infection. one m. mulatta and one m. speciosa were treated daily with prednisolone beginning 2 months after inoculation; worms were recovered from these and 5 other monkeys (7 of 11). microfilaremia was detect ... | 1976 | 816216 |
| failure of carbon monoxide to induce myocardial infarction in cholesterol-fed cynomolgus monkeys (macaca fascicularis). | twenty-six adult female cynomolgus monkeys (macaca fascicularis) were randomly assigned to four groups which were fed on a standard laboratory diet or a semipurified diet containing cholesterol. in two of the groups, the monkeys were exposed intermittently to co throughout the day for 14 months; the control animals breathed room air. no myocardial infarctions were observed, and the ecg showed a transitory injury current in only one animal. no differences in plasma cholesterol levels or in aortic ... | 1976 | 815001 |
| [the weight of the reproductive organs, hypophysis and thyroid of male cynomolgus monkeys. (macaca fascicularis) (author's transl)]. | the present short paper deals with the weight of the male reproductive organs of wild-imported cynomolgus monkeys, including the testes, epididymides, ductus deferens, vesicula seminalis prostata, bulbo urethralis and penis. in addition, the size of the testes and the weight of the thyroid and hypophysis are also presented. | 1975 | 814007 |
| [artificial nursing of new-born cynomolgus monkeys as a model of the human infant and development of abnormal behavior (author's transl)]. | new-born cynomolgus monkeys were sucessfully reared by artificial nursing that was started just afterbirth with a 12% solution of a commercially prepared powdered-milk (yukijirushi, p 7a) containing 13.3g of protein per 100g. marked growth-retardation was observed in baby cynomolgus monkeys fed on a 12% solution of the modified p 7a milk containing only 6.6g of protein per 100g to which lactose was supplemented to give a baby monkey the same caloric value as that of the original p 7a milk. these ... | 1975 | 814006 |
| distribution of an 125i-labelled chloroquine analogue in a pregnant macaca monkey. | whole body autoradiography of a pregnant monkey (macaca irus) of late gestation was performed 72 h after an intravenous injection of the 125i-labelled chloroquine analogue 4-(3-dimethylaminopropylamino)-7-iodoquinoline (dapq). the overall distribution pattern in the monkey was similar to that which was earlier observed in rodents. a few species differences, however, were found in the monkey as compared to the rodents: a high accumulation in the inner part of the adrenal cortex, a high level in t ... | 1975 | 813334 |
| atherosclerosis in rhesus and cynomolgus monkeys. | 1976 | 813206 | |
| schistosoma japonicum: immunopathology of nephritis in macaca fascicularis. | 1975 | 812719 | |
| ocular effects of clonidine in cats and monkeys (macaca irus). | 1975 | 812714 | |
| phenylalanine hydroxylase of macaca irus a simple purification by affinity chromatography. | 1975 | 812698 | |
| clinical note--a case of bilateral dental fistula in a cynamolgus monkey (macaca fascicularis). | 1975 | 811928 | |
| resistance to psychopathology in adolescent monkeys (macaca fascicularis) reared with mothers and peers. | 1975 | 811699 | |
| [characterization of mycoplasms isolated from imported nonhuman primates (author's transl)]. | mycoplasms were isolated from 35 (16%) of 215 specimens collected from 20 crab-eating monkeys (macaca irus), 9 green monkeys (cercopithecus aethiops) and from 9 common squirrel monkeys (saimiri sciurea). all these animals had been imported from south-east asia, africa and south america being apparently healthy. a total of 38 large and 20 small colony-mycoplasma strains were isolated from the nasal and oral cavity, urethra, vagina and rectal feces. the large colony-mycoplasmas could be differenti ... | 1975 | 811474 |
| [changes in cellular activity in corpus luysi after stimulation of monkey corpus striatum]. | in a chronic experiment on three awake macaca cynomolgus, the activity of 27 neurons localized in the corpus luysi was recorded. their spontaneous activity is continuous without rhythmicity or bursts. all neurons responded to a stimulation of the striatum by an initial activation followed by an inhibition. these facts reveal the occurrence of a double projection from the putamen and also from the head of the caudate nucleus to the corpus luysi. | 1975 | 811384 |
| effective body water half-life and total body water in rhesus and cynomolgus monkeys. | although body water content and effective water half-life have been determined in several mammalian species, including man, these measurements are not available for sub-human primates to our knowledge. values were therefore determined in a group of rhesus and cynomolgus monkeys. a fairly wide range of water half-life values was found in each of the two species between animals, but there was little variation within animals who had more than one determination over the course of 1 year. mean values ... | 1975 | 811339 |
| sinusoidal flicker characteristcis of primate cones in response to heterochromatic stimuli. | electrophysiological recordings of primate photorecptors have been obtained and frequency response characteristics of the red, green and blue cones have been determined and compared to previous psychophysical findings. using cynomolgus monkeys, we recorded the foveal local electroretinogram, which is dominated by the late receptor potential, and obtained criterion-response threshold data for sinusoidally flickered test stimuli complementary chromatic adapting backgrounds. our results support the ... | 1975 | 810550 |
| [retinal reactions to intense light. i. threshold lesions. experimental, morphological and clinical studies of pathological and therapeutic effects of laser and white light]. | the effects of intense light produced by an argon laser, a helium-neon laser and a xenon are photocoagulator in the retinas of gray chinchilla rabbits, cynomolgus monkeys, and rhesus monkeys were studied clinically and histopathologically including electron microscopy. an improved experimental set-up was used allowing a very good consistency of the inflicted lesions. threshold lesions were produced in chinchilla rabbits and cynomolgus monkeys by an argon laser and a helium-neon laser. the lesion ... | 1975 | 810008 |
| maximum expiratory flow-volume studies on monkeys exposed to bituminous coal dust. | to assess early ventilatory responses at the 2 mg/m3 bituminous coal dust standard, 23 cynomolgus monkeys were exposed by inhalation to pennsylvania and utah coal dust. ten controls were utilized. pennsylvania coal was selected from a field having a high prevalence of coal workers' pneumoconiosis while the utah coal was selected from a low prevalence area. after 24 mo of exposure, a pattern of pulmonary impairment consistent with peripheral airway obstruction was demonstrated. reductions were ob ... | 1975 | 809410 |
| treatment of squamous cell carcinoma involving the buccal pouch in a crab-eating macaque. | persistent swelling of the left buccal pouch was noticed in an adult female crab-eating macaque (macaca fascicularis). a mass involving almost the entire musculature of the pouch was removed surgically. the histopahtologic diagnosis was squamous cell carcinoma. recurrence of the mass was treated by a combination of surgical excision and radiation therapy. | 1975 | 809400 |
| erythroblastosis models. a review and new experimental data in monkeys. | the current status of erythroblastosis fetalis in man and in animals is briefly reviewed with emphasis on present knowledge of nonhuman primates as models for the disease. our studies in crab-eating macaques indicate that presence in a mother's serum of potent antibodies reactive for red cells for her fetus will not necessarily cause erythroblastosis; in one case the maternal antibodies did not penetrate the placental barrier, and in two cases although the fetal red cells were maximally antibody ... | 1975 | 808623 |
| experimental oroparanasal communication in monkeys. | experimental oroparanasal communications were established in nine monkeys (macaca irus) through the alveoli of the maxillary first or second molars after extraction of these teeth. the communications between the maxillary sinus and the oral cavity were supported by use of a polyethylene catheter fixed with sutures. the observation time ranged from 1 to 6 days. histologic study of the maxillary sinus mucous membrane revealed inflammatory changes especially in the floor and the lower part of the w ... | 1975 | 808503 |
| sulphated macromolecules in dental plaque in the monkey macaca irus. | 1975 | 808203 | |
| the influence of 2 br-alpha-ergocryptine (cb-154) and apomorphine on induced prolactin secretion in the crab eating monkey (macaca fascicularis). | the influence of apomorphine and 2 br-alpha-ergocryptine (cb-154) on drug-induced prolactin secretion was examined in an intact and an ovariectomized monkey (macaca fascicularis). perphenazine administered iv at one mg/kg bw induced a rapid and marked increase in serum prolactin. apomorphine at a concentration of 4 mg/kg bw administered prior to perphenazine delayed the perphenazine-induced prolactin rise. the iv administration of cb-154 at either 200 or 2000 mu-g/kg bw completely blocked the pe ... | 1975 | 807469 |
| effect of sodium phytate on the chemical and microbial composition of dental plaque in the monkey (macaca fascicularis) | the incorporation of 1 or 3% sodium phytate in confectioners sugar produced minimal changes in the physical,chemical, and microbial composition of dental plaque in tube-fed monkeys during a two-week period. only a reduction in yeasts and lactobacilli could be ascribed to the presence of phytate. other changes were attributable to the transition from conventional feeding to tube-feeding, irrespective of the presence of absence of phytate. | 1975 | 806617 |
| the application of qae-sephadex for the purification of two staphylococcal enterotoxins. ii. purification of enterotoxin a. | the last three steps described in the preceding communication robern, h., stavric, s. and dickie, n. (1975) biochim. biophys. acta 000,000-000) were utilized successfully for the purification of enterotoxin a. the enterotoxin appeared homogeneous by gel chromatography and in the analytical ultracentrifuge but showed two bands on polyacrylamide disc electrophoresis at ph 4.5. the emetic dose, ed50, by intravenous route in cynomolgus monkeys was 0.12 mug/kg of animal weight. after treatment with b ... | 1975 | 806302 |
| t-strain mucoplasmas and reproductive failure in monkeys. | t-strain mycoplasmas were isolated from the genital tracts of 3 genera of female monkeys: the talapoins, miopithecas talapoin, the patas, erythrocebus patas, and the macaques, macaca fascicularis. the talapoins have not reproduced successfully for the past 2 yr. fertility in the patas has also been reduced, with a high incidence of stillbirths and spontaneous abortions. the macaques were not permitted to breed. | 1975 | 805883 |
| intrauterine ethanol-induced termination of pregnancy in cynomolgus monkeys (macaca fascicularis). | the effectiveness of locally applied ethanol in terminating early pregnancy in cynomolgus monkeys was studied. in a randomized trial ethanol (70 per cent, 1 ml.) or saline (0.9 per cent, 1 ml.) was injected extra-amniotically through a sterile blunt-end needdle inserted through the cervix into the uterine cavity. six of seven monkeys receiving ethanol showed vaginal bleeding beginning one or two days after treatment. with the one failure, alcohol leakage occurred from the luer-lock needle joint ... | 1978 | 717489 |
| the c-wave of the human electroretinogram in central retinal artery occlusion. | the pigment epithelium-receptor complex, which is supplied from the choroidal circulation, is the main source of the c-wave of the erg. occlusion of the central retinal artery (ocra), which causes serious damage to the inner retinal layers, should therefore not primarily be expected to affect the c-wave amplitude. nevertheless, conflicting reports of increased, decreased and unchanged c-waves have appeared in the literature. in the present study on four patients with ocra the affected eyes showe ... | 1978 | 696268 |
| the electrocardiogram of macaca fascicularis. | electrocardiograms from 16 male cynomolgus monkeys (macaca fascicularis) were studied. standard and augmented limb leads (i, ii, iii, avr, avl, avf) were obtained with the animals restrained in a sitting position. normal electrocardiographic parameters were determined, including pr and qt intervals; p, qrs, and t wave axes; p and qrs wave widths. voltages in all standard and augmented limb leads were lower than previously reported for similar size monkeys. | 1978 | 642439 |
| nursery rearing of infant monkeys (macaca fascicularis) for toxicity studies. | at birth, nine infant male cynomolgus monkeys (macaca fascicularis) weighed an average of 402 g and 16 infant female cynomolgus monkeys weighed an average of 362 g. both female and male infants last 15-20 g by the fourth day after birth. female and male infants showed a growth rate of approximately 4 and 5 g body wt/day, respectively, from 4 to 150 days of age. caloric intake increased from approximately 140 cal/gkg body weight/day in both females and males on the first day after birth to peak v ... | 1977 | 557707 |
| erythroblastosis models. ii. materno-fetal incompatibility in chimpanzee. | erythroblastosis fetalis represents a significant hazard for successful management of pregnancy in man and in marmosets, but not in crab-eating macaques. materno-fetal blood group incompatibility in chimpanzee is described as a contributing factor in the death of an infant. the findings indicate that parental blood groups should be taken into consideration when breeding chimpanzees. | 1977 | 556709 |
| experimental analysis of temporomandibular joint reaction force in macaques. | mandibular bone strain in the region immediately below the temporomandibular ligament was analyzed in adult and sub-adult macaca fascicularis and macaca mulatta. following recovery from the general anesthetic, the monkeys were presented food objects, a wooden rod, or a specially designed bite-force transducer. bone strain was recorded during incisal biting and mastication of food, and also during isometric biting of the rod and/or the transducer. the bone strain data suggest the following: the m ... | 1979 | 532828 |
| between-ovary interaction in the regulation of follicle growth, corpus luteum function, and gonadotropin secretion in the primate ovarian cycle. i. effects of follicle cautery and hemiovariectomy during the follicular phase in cynomolgus monkeys. | 1979 | 436777 | |
| carcinogenic and other adverse effects of procarbazine in nonhuman primates. | the carcinogenic potential of procarbazine is under investigation in three species (macaca mulatta, macaca fascicularis, and cercopithecus aethiops) of nonhuman primates. a total of 55 monkeys have received procarbazine s.c., p.o., or i.p. for periods of up to 12 years. eleven of the 42 monkeys (26%) necropsied thus far have had malignant neoplasms, 6 of which were acute leukemia. two monkeys developed osteogenic sarcomas, two monkeys developed hemangiosarcomas, and a single case of lymphocytic ... | 1978 | 418874 |
| craniofacial adaptations after total maxillary osteotomy in macaca irus: a cephalometric and histologic study. | five macaca irus monkeys were used in this study to determine cephalometric and histologic changes after total maxillary impactions. in the three experimental animals, the maxilla was impacted 5 to 7 mm. and lateral cephalograms were taken over a 150-day period. by superimposing on craniofacial implants, osseous and dental changes were measured. excellent skeletal stability was demonstrated during the postoperative period. histologically, there was normal osseous healing of the osteotomized maxi ... | 1978 | 418689 |
| anticholinesterase-induced cholinergic subsensitivity in primate accommodative mechanism. | i treated cynomolgus monkeys with topical echothiophate iodide twice daily for several months. accommodative responses to topical or intramuscular pilocarpine were determined after ciliary ganglion or cholinergic nerve blockade. during echothiophate treatment, there was little or no accommodative response to intramuscular pilocarpine doses which were near maximal in nonechothiophate-treated eyes. similarly, echothiophate-treated eyes demonstrated little or no response to topical pilocarpine dose ... | 1978 | 418688 |
| effects of ischemia on the oxygen diffusion coefficients in the brain cortex (studies on macaca irus). | in this series of experiments changes in oxygen diffusion coefficients were measured in waking primates undergoing focal middle cerebral artery ischemia; ligation of the middle cerebral artery followed by a decrease of the oxygen diffusion coefficient in the areas supplied by that vessel to levels ten to twenty per cent below normal by twenty-five minutes following onset of ischemia. following release and re-perfusion diffusion coefficient gradually increases and reaches a super normal peak valu ... | 1977 | 418626 |
| prevention of hypercholesterolemia in monkeys (macaca fascicularis) by digitonin. | digitonin mixed in the diet was well tolerated by rats and cynomolgus monkeys (macaca fascicularis), and prevented the expected rise in plasma cholesterol in monkeys fed a diet containing butter and cholesterol. both digitonin and mildly hydrolyzed digitonin precipitated cholesterol dispersed in micellar suspensions and decreased intestinal absorption of cholesterol in rats, but only digitonin bound cholesterol in vitro. the hypocholesterolemic effect of digitonin may be secondary to decreased i ... | 1978 | 417616 |
| [the importance of interferon for rabies prophylaxis (author's transl)]. | the importance of interferon for the prophylaxis of rabies is not yet fully understood. about 50% of cynomolgus monkeys infected with rabies virus could be protected from the disease with human interferon which was administered at a total dose of 1--10 million units per animal either intramuscularly 24 hours after infection or by intralumbar injection up to 11 days after. the clinical relevance of the findings is discussed. | 1978 | 417241 |
| static lung mechanics of intact and excised rhesus monkey lungs and lobes. | subdivisions of lung volume and pressure-volume (pv) curves of the lung and chest wall (cw) were measured in 12 rhesus monkeys (macacca mulatta) under pentobarbital anesthesia. in addition, volumes and pv curves were obtained on the excised lungs and lobes of 12 cynomolgus monkeys (m. fasicularis). boyle's law was used to determine functional residual capacity (frc) in the intact animals and water displacement to determine minimal volume (mv) in the excised lungs. total lung capacity (tlc = lung ... | 1978 | 417053 |
| surface processes of olfactory receptors. | the free surface morphology of olfactory receptor cells from the nasal mucosa of cynomolgus monkeys was studied electron microscopically. the receptor cell, in addition to showing characteristic cilia, possess several branched or unbranched shorter elevations or spiny processes covered by numerous delicate lace-like filaments not previously described. these filaments diminish in length and number toward the base of the microvillous protrusions. | 1978 | 416912 |
| [fluorescence histochemical studies on the monoamine-containing neurons and their pathways in the brain stem of the java monkey (macaca irus)--stereotaxic demonstration of the localization (author's transl)]. | 1977 | 416765 | |
| blood groups of pig-tailed macaques (macaca nemestrina). | the human-type a-b-o blood groups of 57 pig-tailed macaques (macaca nemestrina) were determined and the calculated gene frequencies, o = 0.8908, a = 0.0825 and b = 0.0267, gave excellent fit with the hypothesis of inheritance by triple allelic genes. in tests for simian-type blood groups with rhesus, baboon and crab-eating macaque immune antisera, it was shown that the red cells of pig-tailed macaques are polymorphic for several simian-type specificities defined by those cross-reacting sera. pig ... | 1978 | 416724 |
| effects of plant and animal lipids rich in docosenoic acids on the myocardium of cynomolgus monkeys. | cynomolgus monkeys (macaca fascicularis) were fed diets containing 25% rapeseed oil (rso), partially-hydrogenated herring oil (phho) or a 3:1 mixture of lard/corn oil as control (con) for 4 months. the rso contained approximately 25% of the fatty acids as erucic acid (cis-docos-13-enoic, 22:1w9) while the phho contained a similar concentration of mainly cetoleic acid (cis-docos-11-enoic, 22:1w11). the con contained no 22:1 acids. the monkeys developed the expected myocardial lipidosis, somewhat ... | 1978 | 416402 |
| angiochemical and tissue cholesterol changes of macaca fascicularis fed an atherogenic diet for 3 years. | 1970 | 415900 | |
| north borneo (malaysia): a new locality for schistosoma japonicum. | eleven pairs of schistosomes, indistinguishable from the classical schistosoma japonicum, were found in a monkey (macaca fascicularis) taken near ranau in north borneo. the new locality is within the recorded range of the species which extends from japan, china, taiwan, and philippines through southeast asia to the celebes. | 1978 | 415627 |
| morphologic effects of dietary plant and animal lipids rich in docosenoic acids on heart and skeletal muscle of cynomolgus monkeys. | cynomolgi (macaca fascicularis) were fed diets containing 25% rapeseed oil (rso), partially hydrogenated herring oil (phho), or a 3:1 mixture of lard and corn oil as control for 4 months. the rso contained approximately 25% of the fatty acids as erucic acid; the phho contained a similar concentration of mainly cetoleic acid. the control diet did not include such fatty acids. at the time of necropsy, the rso- and phho-fed monkeys showed myocardial and skeletal muscle lipidosis. foci of mononuclea ... | 1978 | 415615 |
| the enamel--dentine junction of human and macaca irus teeth: a light and electron microscopic study. | the enamel--dentin junction of human and macaca irus teeth has been studied using light and scanning and transmission electron microscopy. there are differences between species and within the same tooth. scalloping, when present, is more developed in the cuspal areas and approximally, and the scallops appear to be formed at the time of maturation of the hard tissues. enamel tufts and spindles are briefly discussed. the depth of scallops was less in the human deciduous than in the permanent teeth ... | 1978 | 415029 |
| rat lung hyper-reactivity to stress. | rats have been used frequently as a model for determining the pulmonary response to various stressful situations. it has been shown in the literature that rat lungs are remarkably sensitive to factors which result in the development of gross pulmonary injury, such as stress from exposure to hyperbaric oxygen. similarly, a high degree of pulmonary reactivity was found in rats after administration of various cns, convulsants and also exposure to mechanical vibration. the present study was confined ... | 1978 | 414726 |
| ornithine decarboxylase activity in tooth surface plaque from monkeys (macaca fascicularis) fed pyridoxine, phytate and invert sugar. | 1977 | 414701 | |
| measurement of hemolytic complement and the third component of complement in nonhuman primates. | complement, determined by hemolytic assay, and the third component of complement (c3), determined by radial immunodiffusion assay, were measured in nine nonhuman primate species. the species studied were the titi (callicebus mollach). the sooty mangabey (cercocebus atys), the thick-tailed galago or bushbaby (galago crassicaudatus panganiensis), the crab-eating monkey (macaca fascicularis), the rhesus monkey (macaca mulatta), the bonnet monkey (macaca radiata), the stumptailed macaque (macaca spe ... | 1977 | 414024 |
| projections from the primary somatosensory cortex to basal ganglia and thalamus in the monkey. | radioactive amino acids were injected into the postcentral cortex (areas 3, 1 and 2) in 6 monkeys (macaca fascicularis). fibers were traced to the ipsilateral putamen, to olszewski's n. ventralis posterior lateralis pars caudalis, n. ventralis posterior medialis and inferior, to n. pulvinaris oralis, n. suprageniculatus and corpus geniculatum mediale pars magnocellularis. furthermore, there were faint postcentral projections to claustrum, n. caudatus, n. centralis lateralis, n. centrum medianum, ... | 1977 | 413731 |
| metabolism of 15-methyl-prostaglandin f2alpha in the cynomolgus monkey and the human female. | 1977 | 413545 | |
| experimental pulpitis in immunized monkeys. | bovine serum albumin (bsa) was topically applied to exposed dentin to assess whether inflammatory reactions can be induced in the pulp of monkeys immunized against bsa. four cynomolgus monkeys received repeated injections of bsa emulsified with freund's incomplete adjuvant. pulp challenge was performed by applying bsa in freshly cut dentin cavities prepared on the buccal surface in 34 teeth. in 29 control teeth ovalbumin (ova) was applied. control applications of bsa were also performed in 15 te ... | 1977 | 413185 |
| effect of cytochalasin b on conventional drainage of aqueous humor in the cynomolgus monkey. | 1977 | 412695 | |
| alpha1-antitrypsin polymorphism in malaysian macaca irus. | alpha1-antitrypsin types were determined in 200 individual specimens of malaysian macaca irus. we found the pattern b in 76 samples, bc in 116, and c in 8. assuming that these patterns are determined by codominant alleles at one locus, this distribution constitutes a significant (p less than 0.001) deviation from hardy-weinberg equilibrium, because of an excess of bc and low prevalence of c. we found no clear evidence for the presence of alpha1-antitrypsin deficiency comparable to the situation ... | 1977 | 412492 |
| the organization of agonistic relations within two captive groups of java-monkeys (macaca fascicularis). | the paper offers a detailed quantitative descripition of the distribution of agonistic activities over the members of two groups of java-monkeys (macaca fascicularis). these groups lived in captivity and were well-established: i.e. they had an extensive network of genealogical relationships. the study pays special attention to agonistic interactions with three or more participants. its main purpose is an analysis of the way dyadic agonistic relations (e.g. dominance relations) are affected by th ... | 1977 | 412345 |
| metabolism of arylacetic acids. 1. the fate of 1-naphthylacetic acid and its variation with species and dose. | 1. [carboxy-14c]-1-naphthylacetic acid has been administered to man, 6 primate species and 4 other mammalian species and the urinary metabolites examined by radiochromatogram scanning and reverse isotope dilution. animals all received a dose of 100 mg/kg and man received 5 mg, orally. 2. most species excreted at least 60% of the 14c in the urine in 48 h. unchanged acid was a minor (0-17% dose) excretion product in all species except the cynomolgus monkey (35%). 3. in man, in 24 h 95% of 14c was ... | 1977 | 412330 |
| serum estradiol and progesterone during pregnancy and the status of the corpus luteum at delivery in cynomolgus monkeys (macaca fascicularis). | levels of estradiol and progesterone in peripheral serum of seven cynomolgus monkeys (macaca fascicularis) were measured from about the 30th day of pregnancy until parturition. although the pattern of each steroid in circulation differed somewhat from the respective patterns in rhesus monkeys (macaca mulatta), there were basic similarities. on the day of delivery, the corpus luteum was excised and in vitro incubation of dispersed luteal cells was performed. isolated luteal cells produced progest ... | 1977 | 412283 |
| a direct ventral connection between the bed nucleus of the stria terminalis and the amygdaloid complex in the monkey (macaca fascicularis). | a direct ventral connection, between the bed nucleus of the stria terminalis and the amygdaloid complex in the monkey is described. it consists of bundles of extremely fine unmyelinated axons of a median diameter between 0.16 and 0.2 micrometer. the total number of axons is estimated at over 500,000. using observations gained by other authors it is deduced, that the direction of conduction is probably from the bed nucleus of the stria terminalis to the amygdala. other observations in the literat ... | 1977 | 411830 |