Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [study of genetic control of synthesis of type iii and 6th group-specific antigens of flexner shigellae]. | as revealed in experiments of interspecific and intraspecific crosses, the determinant responsible for the group-specific 6, as well as controling the synthesis of type iii antigens of sh. flexneri were localized near the lac-pro markers on the chromosome. in intraspecies crosses of bacteria of y variant with the donor sh. flexneri 3c strain the percentage of linking of lac+a6+ was 32, and of lac+aiii+ --24. genetic confirmation of the dependence of the function of the a6 (defined as att6) deter ... | 1977 | 68643 |
| [role of several functional groups in the biological activity of allergenic preparations]. | 1976 | 66777 | |
| [several allergic reactions under conditions of functioning of an inhibitor of antibody activity in the body]. | allergization under conditions of functioning an inhibitory factor in the organism was studied by the reaction of leukocytolysis with tsuverkalov's dysenterin and in the reproduction of hypersensitivity of the immediate type on the schultz-dale's model. it was shown that in functioning an inhibitory factor in the organism the degree of leukocytolysis reaction with the dysentery allergen decreased in the immunized animals in parallel with the fall in the serum antibody activity. a depression of t ... | 1977 | 65882 |
| studies on the pathogenesis of enteric infections caused by invasive bacteria. | salmonellae, shigellae and some escherichia coli must invade the intestinal epithelial cell and multiply within the mucosa to cause disease. although the bacterial cell most likely possesses several properties essential to this invasive ability, the nature of the cell envelope complex is at present the only characteristic which has been implicated in this process. while a number of pathophysiological events result from invasion, some of our recent efforts have concerned the site and mechanism of ... | 1976 | 62646 |
| tissue culture in the inherited corneal dystrophies: possible applications and problems. | 2001 | 60147 | |
| visual pattern evoked responses and blink reflexes in assessment of ms diagnosis. a clinical study of 135 multiple sclerosis/pathol. | veps were measured after pattern reversal in 135 ms patients and 30 control subjects. neurological findings were documented in a standard manner. an extensive ophthalmological examination of all subjects was part of the study. the latency of p2 was abnormally delayed in 82% of the "definite", in 60% of the "probable" and in 65% of the "possible" ms groups respectively. the vep was more often delayed in relation to ophthalmological disturbances. changes in the ms classification had to be made in ... | 2001 | 59795 |
| the cutaneous reactions to kallikrein, prostaglandin and thurfyl nicotinate in chronic urticaria and the effect of polyphloretin phosphate. | the erythema and wealing resulting from the application of thurfyl nicotinate ointment (trafuril) and from the inoculation of kallikrein has been studied in patients with chronic urticaria and normal controls. polyphloretin phosphate (ppp) suppressed the reaction in controls but in patients with urticaria it increased the reactions to trafuril and had little effect on the kallikrein reaction. ppp also suppressed the pge2-induced erythma in normal controls but not in urticaria patients. in a sepa ... | 1976 | 59506 |
| [the metabolism of 4-14c-pregnenolone in tissue sections of human ovaries and their modification by chlormadinone acetate]. | in vitro incubations with slices of two normal human ovaries and 4-14c-pregnenolone as precursor were carried out to study the possibility of a direct influence of chlormadinone acetate on the metabolism of pregnenolone. in agreement with our previous studies the incubations of the ovary from the follicle phase of the cycle yields a profile of steroids different from that of the ovary from the corpus luteum phase of the cycle. under the experimental condition chosen, the presence of enzymes of ... | 1975 | 58782 |
| [receptor sites for phages specific for r mutants of shigella flexneri]. | 1975 | 58628 | |
| [localization on the shigella flexneri f6s chromosome of a rfa gene implicated in the biosynthesis of bacterial cell wall lipopolysaccharide]. | 1975 | 58625 | |
| staining and destaining polyacrylamide gels: a comparison of coomassie blue and fast green protein dyes. | 2001 | 58568 | |
| correlation of light and scanning electron microscopy a new method for exfoliative cytology. | a method for preparing locator slides for light and scanning electron microscopy has been developed. these slides make possible correlation of light and scanning electron microscopy of individual cells. some examples of the value of this method are given. | 2001 | 58516 |
| [sensitivity of dysentery bacteria to furazolidone and phthalazol according to the materials of medical epidemiological station of odessa-kishinev railroad]. | 1976 | 58090 | |
| letter: daunorubicin cardiotoxicity. | 2001 | 55702 | |
| editorial: coronary heart-disease in edinburgh and stockholm. | 2001 | 55656 | |
| letter: si chaos. | 2001 | 55546 | |
| letter: impending heart-attacks. | 2001 | 55545 | |
| levamisole in advanced human breast cancer. | a clinical trial of levamisole, an orally effective modifier of the immune response, is reported in women with primary inoperable breast cancer (stage iii). after being rendered clinically disease-free by radiotherapy to the breast, supraclavicular area, and axilla, patients were allocated alternately to a control group (no further treatment) and a levamisole-treated group (150 mg orally three times a week on alternate weeks) and were followed-up by physical examination and laboratory tests. in ... | 1976 | 55529 |
| [obtaining purified preparations of individual shigella newcastle k- and o-antigens by using an ultracentrifugation method]. | a modified method of obtaining the purified k- and o-antigens of sh. newcastle with the use of ultracentrifugation is described. serologically individual k- and o-antigens were obtained and their chemical composition was studied. polysaccharide of the k-antigen consisted of the galacturonic acid, galactose, glucose, rhamnose xylose and hexosamine; it contained no heptoses. the o-antigen contained galactose, glucose, mannose, rhamnose, heptose and hexosamine; in difference to k-antigen was equal ... | 1975 | 55023 |
| [study of the role of type-specific antigen in the process of shigella flexneri interaction with epithelial cell and macrophage cultures]. | epithelial cells of the hep-2 line infected in parallel by genetically connected strains of sh. flexneri, differing in the capacity to synthesize the type antigen were studied morphologically. the type antigen proved to show no significant influence on the penetration of dysentery bacilli into the cell. a study of the process of phagocytosis of the mentioned strains by a culture of peritoneal macrophages of guinea pig demonstrated that the presence of a type antigen communicated to the bacteria ... | 1975 | 55022 |
| [study of the ability of shigella sonnei and flexneri to inactivate antibiotics]. | 1975 | 54495 | |
| [proceedings: new method for chronic implantation of cortical electrodes]. | 1975 | 54071 | |
| drugging a defendant: arm-chair ethics? | 1995 | 41820 | |
| pharmacokinetics of the new beta-adrenoceptor blocker sl 75212 in man after repeated oral administration [proceedings]. | 1979 | 41560 | |
| a marker induction mechanism for the establishment of ordered neural mappings: its application to the retinotectal problem. | 1995 | 41273 | |
| [psychological prevention of fatigue and functional diseases of the cardiovascular system in pilots by means of autogenic training]. | 1996 | 40066 | |
| [comparative study of interferon production in mice with the graft versus host reaction]. | mice with graft versus host reaction (gvhr) show a decreased production of serum interferon and that produced by the bone marrow and spleen cells and blood leukocytes in vitro upon inoculation with newcastle disease virus. interferon induction with lipopolysaccharide of flexner bacteria resulted in activation of production of serum interferon and that induced in spleen cell and blood leukocyte suspensions. serum interferon production after administration of poly(i) . poly(c) was similar in mice ... | 1978 | 34929 |
| effects of water soluble splenic extracts on intestinal smooth muscle. | 1978 | 34364 | |
| [studies on cardiac principle in aconite roots. i. isolation and structural determination of higenamine (author's transl)]. | 2000 | 34017 | |
| pseudomonas arthritis following puncture wounds of the foot. | 1979 | 34012 | |
| study on the ion-permeability of human dental enamel with special reference to an electrochemical approach. | 1977 | 34011 | |
| the uptake of choline by streptococcus pneumoniae. | uptake of choline, a structural component of pneumococcal c- and f-teichoic acids, into bacteria growing in a defined medium was very efficient with an uptake constant ([s]10 5) of 3.2 microns. it was inhibited by iodoacetate, dinitrophenol and oligomycin but not by structural analogues of choline. ethanolamine, however, was transported in the absence of choline but with a reduced affinity ([s]0.5 71.4 microns). the same constitutive system was probably used by both ethanolamine and choline. it ... | 1978 | 34010 |
| hepatic microsomal metabolism of epinephrine and adrenochrome by superoxide-dependent and -independent pathways. | 1979 | 31892 | |
| neuroendocrine embryology and the apud concept. | in the vertebrata the great majority of cells producing hormonal peptides belong to the apud series and share its distinctive cytochemical and ultrastructural characteristics. according to the concept all members of the series are to be regarded as derivatives of neuroectoderm or of specialized (placodal) ectoderm. for most of the apud cells this criterion is fulfilled in that their origin from neural tube, neural ridges or neural crest can be considered proven. complete proof is not yet availab ... | 2001 | 29734 |
| [effect of adsorption on the structure and properties of hemoglobin]. | adsorption spectra of hb+ and hbo2 adsorbed on silica and monolayers cholesterol supported on silica have been studied. it is shown that immobilization leads to new states of proteins, their properties depending on the nature of support and conditions of adsorption. adsorption of haemoglobin leads to its inactivation. the rate of inactivation decreases with an increase of surface concentration of haemoglobin and with simultaneous adsorption of inert proteins. | 2001 | 29668 |
| [international conference on fire safety in hospitals and nursing homes: 5-minute episodes from fire catastrophes]. | 2001 | 29351 | |
| [the stability of metoclopramide solutions in glass and plastic containers. 32. problems of filling plastic containers with fluid drug preparations]. | 2000 | 27824 | |
| neurochemical and operant behavioral studies of a strain of alcohol-preferring rats. | the levels of serotonin (5-ht), 5-hydroxyindoleacetic acid, tyrosine (tyr), norepinephrine (ne), acetylcholine, gaba, glutamate (glu), aspartate (asp), alanine, glycine (gly) and taurine were measured in the cns of adult male rats selectively inbred to the f8 generation for alcohol preference (p) and non-preference (np). with respect to the values found in the np group, higher levels of 5-ht, gaba, glu and gly and lower levels of asp were found in the diencephalon-mesencephalon (d-m) and higher ... | 1978 | 27820 |
| [a case of alclofenac induced asthma (author's transl)]. | 1998 | 27661 | |
| environment and selfsufficiency of elder man (author's transl). | the problems of environment of elderly people are concentrated in social area and in the intimate living space, which can not be maintained sufficiently because of increasing age and decreasing performance. the consequences of mobility in industrial revolution scattered families and also deprived old men of their helpers. inadequate living rooms and absence of technical comfort especially in the houses of the very aged men produce intense dependence of the own individual performance. medical dat ... | 1978 | 27118 |
| beta adrenergic blockade, regional left ventricular blood flow and st-segment elevation in canine experimental myocardial ischemia. | the effects of dl-propranolol, d-propranolol, dl-pindolol and dl-practolol on regional myocardial blood flow (assessed by means of tracer microspheres) and on st-segment elevation in ischemic and nonischemic areas of the canine left ventricle have been investigated. dl-propranolol and dl-pindolol, but not dl-practolol and d-propranolol, induced blood flow redistribution from the epicardium to the endocardium both in ischemic and nonischemic areas. dl-propranolol-induced redistribution was abolis ... | 1978 | 26795 |
| properties of four molecular forms of n-acetyl-beta-d-hexosaminidase isolated from germinating seeds of fenugreek (trigonella foenum graecum). | 1999 | 25183 | |
| congenital testicular lymphangiectasis. | testicular lymphangiectasis are described for the first time in a patient with bilateral inguinal cryptorchidism. a great number of irregular lymphatic channels was observed within the parenchyma and the tunica vasculosa in both testes. large and numerous anastomosis between the lymphatic vessels of these two areas could also be seen. the mtd and the tfi of the left testis were normal. both parameters were very low in the right testis. the association of this fact with the greater development of ... | 1997 | 24294 |
| on the function of the gamma-glutamyl cycle in the transport of amino acids and peptides. | 1997 | 23264 | |
| a case of self-diagnosis. | 1997 | 23201 | |
| inosine analogs as substrates for adenosine kinase--influence of ionization of the n-1 proton on the rate of phosphorylation. | 1999 | 23125 | |
| proteolytic enzymes of the k-1 strain of streptomyces griseus obtained from a commercial preparation (pronase). effect of ph, metal ions, and amino acids on aminopeptidase activity. | 1978 | 22544 | |
| calf liver nuclear n-acetyltransferases. purification and properties of two enzymes with both spermidine acetyltransferase and histone acetyltransferase activities. | calf liver contains two nuclear n-acetyltransferases which are separated by chromatography on hydroxylapatite. both acetyltransferase a and acetyltransferase b will transfer acetate from acetyl-coa to either histone or spermidine. the same protein catalyzes the reaction with both substrates; this is shown by a constant ratio of spermidine to histone activity over a 5,000-fold purification and identical heat denaturation kinetics for both spermidine and histone acetyltransferase activity with eac ... | 1978 | 22543 |
| liver enzyme adaptation after lithium administration in handled and nonhandled rats. | we have examined the interaction of lithium administration and the infant stimulation procedure of handling on hormonally regulated enzymes of liver. animals handled in infancy show an increased morning corticosterone level in response to lithium feeding and markedly elevated serum glucose during refeeding following a two day fast, when compared to non-handled control animals. lithium alters serum corticosterone both in response to the stress of fasting, and during the diurnal cycle following gl ... | 1977 | 21840 |
| enzymes of nitrogen metabolism in legume nodules. purification and properties of nadh-dependent glutamate synthase from lupin nodules. | an nadh-dependent glutamate synthase has been purified 500-fold from the plant cytoplasm fraction of lupinus angustifolius nodules. it consists of a single polypeptide chain, mr 235000. the optimum ph is 8.5, at which km values for 2-oxoglutarate, glutamine and nadh are 39 micrometer, 400 micrometer and 1.3 micrometer respectively. the catalytic centre activity is of the order of 70 s-1 and is independent of ph between 6.5 and 9.5. glutamate synthase is inhibited by glutamic acid, oxaloacetic ac ... | 1999 | 21790 |
| drug effects on blood pressure and heart rate in unanesthetized animals. (1). effects of beta-blocking agents (author's transl). | beta-blocking actions of orally administered kö 1400 and tiprenolol, new beta-blocking agents, were studied in unanesthetized rats and dogs, using a fall of blood pressure and an increase in heart rate produced by isoproterenol as a measure of beta-receptor activation. blood pressure was recorded from the aorta of the dog and the caudal artery of rat via indwelling catheter, and heart rate of the dog was recorded by a cardiotachometer triggered by r waves of the lead ii electrocardiogram. mean r ... | 1977 | 20392 |
| the use of titanium (iv) oxide for the immobilisation of carbohydrate-directed enzymes. | the use of particles of porous titanium (iv) oxide as a suitable matrix for enzyme immobilisation has been investigated with dextranase. treatment of the particles with enzyme in the presence and absence of ammonium ions showed that the presence of ammonia induced a greater coupling of protein, whereas a greater retention of enzyme specific activity was achieved in the absence of ammonia. properties of the immobilised enzyme include a ph-dependence and reversibility of the coupling between enzym ... | 1998 | 20228 |
| role of phospholipids in muscarinic binding by neural membranes. | 1977 | 20109 | |
| effect of oligomycin on coupling in isolated mitochondria from oligomycin-resistant mutants of saccharomyces cerevisiae carrying an oligomycin-resistant atp phosphohydrolase. | 1977 | 20055 | |
| altered mitochondrial metabolism in circulatory shock. | 1998 | 19942 | |
| [ph-potentiometric study of 1-isadrine, 1-teranole and related compounds]. | 1999 | 18365 | |
| testicular androgen binding protein (abp) - a parameter of sertoli cell secretory function. | using abp as an index of sertoli cell secretory function, several important features of the sertoli cell have emerged: 1. the stimulation of abp production by fsh clearly points to the sertoli cell as a target cell for fsh (3,4,9-16,21,24). 2. the dramatic effects of androgens on abp production both in immature and mature rats also suggest that the sertoli cell is a target cell for androgen (3,12,14,16,25). 3. the striking reduction in abp production in the cryptorchid testis raises the question ... | 1975 | 18322 |
| detection of salmonella antigens in the neutralization reaction (anr). | 1977 | 17975 | |
| identification of essential histidine residues of aminoacylase by photooxidation and by reaction with diethylpyrocarbonate. | state and function of the histidine residues of aminoacylase were investigated by photoxidation in the presence of methylene blue and by chemical modification with diethylpyrocarbonate. complete inactivation of the enzyme was observed after oxidation of 4 histidine residues. from the ph dependence of the photooxidation it becomes evident that the inactivation of the enzyme is not a consequence of the simultaneous oxidation of tryptophan residues. the enzyme is also inactivated by chemical modifi ... | 1977 | 17959 |
| [hungarian-made titanium-polyamide knee joint prosthesis]. | 1999 | 17789 | |
| parkinson's disease. | the classical clinical picture of parkinson's disease is all too frequently encountered in the elderly patient. the modern classification of causes of parkinson's disease lists 'idiopathic', and 'post-encephalitic forms', the latter being uncommon in this community. | 2000 | 16582 |
| acute bacteremia in asplenic renal transplant patients. | four cases of overwhelming bacteremia were observed in asplenic renal transplant patients 12 to 20 months after transplantation. the bacteriologic findings and presentation of these infections are characteristic of post-splenectomy sepsis reported in nontransplant patients. it is suggested that the absence of the spleen, more than immunosuppression with azathioprine and prednisone, predisposes to these late, uncommon infections after transplantation. | 1977 | 16144 |
| maternal and neonatal risk at caesarean section. | 2000 | 15786 | |
| risk to the new-born from caesarean section. | 2000 | 15785 | |
| purification and characterization of a plasminogen activator secreted by cultured human pancreatic carcinoma cells. | a plasminogen activator secreted by cultured human pancreatic carcinoma (mia paca-2) cells has been purified to apparent homogeneity by procedures including sepharose-l-arginine methyl ester affinity chromatography, sephadex g-200 gel filtration, isoelectric focusing, and sodium dodecyl sulfate gel electrophoresis. the plasminogen activator shares many properties with urokinase including: molecular weight (55 000), isoelectric point (8.7), heat stability (60 degrees c, 30 min), ph stability (1.5 ... | 1977 | 15590 |
| kallikrein inhibitors in rat plasma. | the kallikrein inhibitor contents of human and animal plasma were determined with glandular kallikreins ec 3.4.21.8. one ml of plasma could inactivate 20-700 kallikrein units (ku). rat plasma was the most potent and inactivated 230-700 ku. however, no enzyme capable of inactivating kallikrein could be found in this plasma. two fractions which inhibited hog pancreatic kallikrein, a fraction corresponding to alpha2-macroglobulin and a fraction which was eluted prior to albumin, were separated from ... | 1977 | 14935 |
| comparative in vitro studies of cinoxacin, nalidixic acid, and oxolinic acid. | cinoxacin and nalidixic acid were found to be similar in in vitro activity against 138 shigella isolates and somewhat less active than oxolinic acid on a weight basis. cross-resistance developed when 10 shigellae were transferred on increasing amounts of the respective agent contained in mueller-hinton agar. plate dilution studies of the effect of changes in agar ph on the minimum inhibitory concentration revealed that the antibacterial activity increased with decreasing ph. protein binding inve ... | 1976 | 12717 |
| lactulose therapy in shigella carrier state and acute dysentery. | antibiotic-resistant shigella are increasingly prevalent. lactulose, a non-absorbable disaccharide, was investigated as an alternative therapy for shigella infection on the hypothesis that the short-chain fatty acids (inhibitory to shigella) resulting from metabolism of lactulose by normal colonic flora would diminish shigella excretion. a long-term antibiotic-refractory carrier (large bowel) excreting 10(4) to 10(7)shigella sonnei/g of feces was given two courses of lactulose (of 24 and 16 days ... | 1975 | 2098 |
| use of lincomycin, methicillin and ristomycin in the nutrient media for isolating pathogenic intestinal microorganisms. | elective-differentiating solid nutrient media for simultaneous isolation of vibrioes, salmonella and shigella were developed. antibiotics active against grampostive microflora and dry bile salts inhibiting the growth of proteus were used as the inhibitors of the growth of the accompanying microflora. the medium was lincomycin and the bile salts may be prepared in a dry form. | 1975 | 2096 |
| the cathode bound group antigen of dysentery-provoking escherichieae (author's transl). | antigens from disrupted cells of dysentery-provoking and of non-enteropathogenic escherichieae were submitted to immunoelectrophoresis on cellulose acetate stripes at ph 8.0. among 6 immune sera produced for this purpose by immunizing rabbits against desintegrated dysentery bacteria, only one contained a precipitine reacting with an antigen similar to the "generic antigen" of belaya. this - at ph 8.0 - cathode-bound group antigen (kga) could not only be found in virulent but also in 5 attenuated ... | 1975 | 873 |