Publications

prevalence of verocytotoxigenic escherichia coli in ground beef, pork, and chicken in southwestern ontario.	samples of ground beef (225), pork (235) and chicken (200) were randomly selected from meat processing plants in the southwestern ontario area. supernatants of broth cultures of the samples were tested for verocytotoxins using a vero cell assay. neutralization of cytotoxic activity using antisera specific for three types of verocytotoxin (verotoxin 1, verotoxin 2 and shiga-like toxin ii) was performed on positive samples. isolation of verocytotoxigenic escherichia coli (vtec) was attempted from ...	1990	2200697
report of the international committee on nickel carcinogenesis in man.		1990	2185539
new blood safety tests. ottawa.		1990	2175725
universal precautions to prevent hiv transmission to health care workers: an economic analysis.	the universal precautions recommended by the us centers for disease control (cdc), atlanta, for the prevention of hiv (human immunodeficiency virus) transmission to health care workers are widely accepted, despite little documentation of their effectiveness and efficiency. we reviewed the evidence on the risk of hiv transmission to hospital workers and the effectiveness of the universal precautions. we also evaluated the costs of implementing the recommendations in a 450-bed acute care teaching ...	1990	2158390
geographical distribution of contaminants and productivity measures of herring gulls in the great lakes: lake erie and connecting channels 1978/79.	the distribution and size of colonies, residue levels of dde, ddt, hcb, dieldrin, mirex and pcbs in eggs, productivity and eggshell thickness were determined for herring gulls at 14 sites in lake erie and connecting channels. the centre of distribution for breeding herring gulls was the western basin where approximately 90% of the 6200 nests in the study area were located. seven of 22 colonies showed an average annual population increase of 48.3%. most of the increase in breeding herring gulls o ...	1990	2108495
hepatitis b and human immunodeficiency virus infection in street youths in toronto, canada.	hepatitis b and human immunodeficiency virus are transmitted by venereal contact or by the sharing of used needles during drug use. a questionnaire was administered to street youths admitting to prostitution and to a group denying prostitution, as well as to sexually active adolescents who lived with their family and were attending an adolescent medical clinic. the age, gender, race, number of sexual partners, condom use, illicit drug use, anal intercourse and admission to prostitution were reco ...	1991	2062604
review of human and animal cases of coccidioidomycosis diagnosed in canada.	the first canadian case of coccidioidomycosis in a human was reported in 1952 and 11 more cases since then. this study provides details of other cases of coccidioidomycosis that have been diagnosed in canada. based on clinical details, isolation of coccidioides immitis, detection of a specific antibody (f band) for coccidioidomycosis by macro- or microimmunodiffusion tests, concurrently used with the complement fixation procedure, and histopathological findings, 116 more cases of this disease we ...	1991	2014046
a collaborative model for the clinical education of baccalaureate nursing students.	quality clinical supervision is fundamental for the consolidation of knowledge and the development of a professional identity for baccalaureate nursing students. problems in providing high-quality clinical supervision range from a lack of practitioner role models to inadequate or unsupportive learning environments. collaboration between the education and service sectors allows for the development of enriched clinical learning experiences for students. this paper describes an innovative collabora ...	1991	2005282
[access to equal employment: retrospective studies and perspectives].	reaching for more fair representation of women in all levels and in all areas of employment involves a fundamental change in mentalities and administrative practices. following twenty years of efforts to improve women's situation, where are we now? do men and women approve of the same strategies to eliminate sex discrimination? we will address these questions by relying on results obtained in the context of a research program developed at the university of ottawa. the results of these studies le ...	1991	1958651
effect of repeated annual reminder letters on influenza immunization among elderly patients.		1991	1890400
results of a province-wide quality assurance program assessing the accuracy of cholesterol, triglycerides, and high-density lipoprotein cholesterol measurements and calculated low-density lipoprotein cholesterol in ontario, using fresh human serum.	to evaluate laboratory performance, eight to 13 samples of fresh human serum from volunteers were sent to 250 laboratories in the canadian province of ontario licensed to perform lipid analysis. fresh human specimens were used because of potential matrix effects with processed materials. we show that on all survey samples, 71% (range, 63% to 82%) of participating laboratories are within +/- 5% of the target cholesterol value and that 93% are within +/- 10%. the goal of the national cholesterol e ...	1991	1768212
the canadian atherosclerosis society--history and present status.	since its inception in 1983 the canadian atherosclerosis society (cas) has established itself firmly on the national and international scene as a forceful scientific voice. its presence and activities have had their dominant expression at annual meetings held jointly with the royal college of physicians and surgeons of canada (rcpsc) and the canadian society for clinical investigation (csci) and in sponsoring other scientific and educational events, the most important of which was the canadian c ...	1991	1742671
shut out flu.		1992	1737303
virology laboratory diagnosis of chronic fatigue syndrome.		1991	1669355
carcinoma of the lung in ontario gold miners: possible aetiological factors.	a cohort of 54,128 men who worked in ontario mines was observed for mortality between 1955 and 1986. most of these men worked in nickel, gold, or uranium mines; a few worked in silver, iron, lead/zinc, or other ore mines. if mortality that occurred after a man had started to mine uranium was excluded, an excess of carcinoma of the lung was found among the 13,603 ontario gold miners in the study (standardised mortality ratio (smr) 129, 95% confidence interval (95% ci) 115-145) and in men who bega ...	1991	1663386
distribution and characteristics of verocytotoxigenic escherichia coli isolated from ontario dairy cattle.	faecal swabs obtained from a random sample of 1131 cows and 659 calves on 100 southern ontario dairy farms were examined for verocytotoxigenic escherichia coli (vtec) using a vero cell assay. five isolates from each positive culture were tested similarly. positive colonies were examined with dna probes for shiga-like toxin i (slt-i) and slt-ii sequences. probe-negative colonies were tested for neutralization of verocytotoxicity using anti-slt-i and anti-slt-iiv antisera. colonies showing no neut ...	1992	1601076
family physicians' attitudes toward advance directives.	to examine the attitudes toward, the experience with and the knowledge of advance directives of family physicians in ontario.	1992	1596842
schneiderian papilloma of the nose and paranasal sinuses: the university of ottawa experience.	schneiderian papillomata of the nose and the paranasal sinuses are uncommon neoplasms. although histologically benign, malignancy can occur. the likely etiologic agent is the human papilloma virus. we reviewed the cases treated at university of ottawa-affiliated hospitals from 1969-1989. there were 35 patients consisting of 26 men and nine women with an average age of 55.8 years. the most common presenting symptom was unilateral nasal obstruction (71.4%). this was caused in most cases by an ipsi ...	1992	1564756
prevalence of hepatitis b surface antigen, hepatitis c antibody, and hiv-1 antibody among residents of a long-term-care facility.	to determine the prevalence of hepatitis b antigen (hbsag), antibody to hepatitis c virus (anti-hcv), and antibody to human immunodeficiency virus (anti-hiv) among residents of a long-term care facility.	1992	1538038
influenza immunization program in long term care facilities.	infection control, nursing and occupational health at st mary's hospital and marian villa home for the aged collaborated to develop, present and evaluate a successful influenza immunization program for patients, residents and staff. the methods used may be applied to any health care facility for a major immunization program. the success of the program can be attributed to the enthusiastic efforts of all three departments and a dedicated task force.	1992	1525380
absence of human t-lymphotropic virus types i and ii infection in an ontario hemophilia population.	two hundred ninety-three serum samples from ontario hemophiliacs and 200 samples from human immunodeficiency virus-positive blood donors were screened for the presence of antibodies to human t-lymphotropic virus type i (htlv-i) by enzyme-linked immunosorbent assay, radioimmunoassay, and western blot techniques. none of the serum samples provided unequivocal positive results, but several samples gave inconclusive results. of the hemophiliacs with inconclusive serologic results from whom periphera ...	1992	1502703
vehicle injuries to joggers. case report and review.	a medico-legal case is presented where a jogger was struck by a car while crossing an intersection and later sought major damages in a civil court. this incident is reviewed in the context of overall information on injury to joggers by vehicles, and the possibility (raised by the defendant's counsel) that the euphoria generated by prolonged exercise may have created a sense of "invincibility" that predisposed the jogger to reckless actions. the defendants argued that the young man concerned was ...	1992	1487926
prevalence of antibody to human t-cell lymphotropic virus type i/ii in people of caribbean origin in toronto.	to estimate the prevalence of antibody to human t-cell lymphotropic virus type i/ii (anti-htlv-i/ii) in people from an htlv-i/ii-endemic area (the caribbean) living in a nonendemic region (canada).	1992	1423089
absence experience of career firefighters reaching mandatory retirement age.		1992	1403190
indoor air '90: the 5th in a series of international conferences on the indoor environment.	the 5th international conference on indoor air quality and climate: indoor air '90 continued a series of international scientific conferences begun in 1978 on a complex, interdisciplinary subject increasingly recognized to be of importance to human comfort, health and productivity, and having important implications for building design and furnishing, office equipment, appliances, cleaning, heating, ventilating, humidifying and air-conditioning. indoor air '90 constituted a week long program of 5 ...	1992	1363431
possible influence of measles virus infection of cynomolgus monkeys on the outcome of the neurovirulence test for oral poliovirus vaccine.	macaque monkeys are susceptible to measles infection which triggers temporary immuno-depression similar to the well known phenomenon in humans. it is known that feral monkeys become infected with measles virus when they are exposed to humans. since macaca mulatta and m. fascicularis are species used to assay the neurovirulence of oral poliovirus vaccine, the immunodepression caused by measles infection of the test monkeys could significantly alter the results of the neurovirulence test. the seru ...	1992	1319180
prevalence of bloodborne infective agents among people admitted to a canadian hospital.	to determine the prevalence rates of hepatitis b surface antigen (hbsag) and antibodies to the human immunodeficiency virus (anti-hiv) and the hepatitis c virus (anti-hcv) among people admitted to an urban canadian hospital.	1992	1313326
sociocultural variation in sick role behavioural expectations.		1976	1265488
human aural myiasis: a case in ontario, canada, and a partial review.		1976	1255358
the human hemoglobin variants in canada.	this report summarizes the results of a search for abnormal hemoglobin variants by use of a filter paper electrophoresis technique on 228,300 blood samples obtained from various parts of four canadian provinces. abnormal variants were found in 438 samples and were of 27 different varieties, including six new ones. in addition, the characteristics of beta-thalassemia were found in 147 samples. the types of variant found, and their geographical and ethnic origin are presented.	1975	1201625
distribution of organochlorine pesticides in an agricultural environment, holland marsh, ontario--1970-72.	analaysis of organochlorine pesticides in soil, fish, and human blood samples from holland marsh, ontario, indicates that although total ddt is present in detectable amounts, it does not constitute a hazard to human health and longevity. among soils tested, residues were highest in surface samples. ddt levels in human blood samples were similar to those in u.s. and british studies.	1975	1181548
comparative study of ddt and its derivatives in human blood samples in norfolk county and holland marsh, ontario.		1975	1131452
autopsy data and their total evaluation.	the role of the autopsy is discussed in the study of the etiology of the current major causes of death (cardiovascular and neoplastic diseases) in developed countries. evidence is accumulating for the importance of environmental factors in the etiology of these diseases. the study of regional differences in occurrence is described as a method of identifying specific factors. maps are shown of mortality rates for all causes of death in ontario counties for males aged 65-74 and 95+ during 1964-68. ...	1975	1109383
alan brown, the man.		1975	1098761
the ombudsman in mental health: lakeshore's experience.		1976	1027535
fatal human infection with mesocercariae of the trematode alaria americana.	a fatal human infection with mesocercafiae of alaria americana is described. several thousand mesocercariae were estimated to be present in the peritoneal cavity, bronchial aspirate, brain, heart, kidney, liver, lungs, lymph nodes, pancreas, retroperitoneal adipose tissue, spinal cord, spleen, and stomach. nine days from the onset of symptoms death resulted from asphyxiation due to extensive pulmonary hemorrhage probably caused by immun-mediated mechanisms. circumstances suggest the victim proba ...	1976	1008125
marfan syndrome with coronary artery lesions in a north american indian.	marfan syndrome has not been well documented in north american indians. a 19-year old ojibwa man had evidence of this syndrome -- specifically, tall stature, long, thin extremities (particularly, fingers and toes), increased urinary excretion of hydroxyproline, aortic aneurysm, aortic regurgitation and pathologic evidence of aortic rupture and alastic tissue fragmentation. intimal hyperplasia was present in the extramural coronary arteries, while the intramural arteries, usually thought to be in ...	1976	974953
crowding and human reproduction.	studies of crowding in lower animals repeatedly demonstrate that compressed living conditions depress the ability of the species to reproduce. in a sample of 470 urban toronto women we examined the effect of neighborhood and household crowding on the probability of a pregnancy and on the probability that any given product of the pregnancy will not survive until one year of age. crowding did not influence fertility nor fetal and infant survival within the range of crowding found in this sample. ...	1976	958631
organochlorine residues in human adipose tissue and milk from ontario residents, 1969-- 1974.		1977	849578
physician contributions to nonmedical science: davidson black, our peking man.		1976	793707
gonorrhea in homosexual men.	extragenital gonorrhea was seen in 65% of 54 cases of gonorrhea in 43 homosexual men attending a venereal diseases clinic between 1974 and 1977; in 21 cases the infection was extragenital only. this type of gonorrhea was often asymptomatic and was associated with a high rate of failure of initial treatment in 6 of the 50 cases in which the patient returned for follow-up assessment, and in 5 of the 6 the persistent infection was extragenital. syphillis was seen concomitantly or had previously occ ...	1978	709473
isolation of yersinia enterocolitica from surface and well waters in ontario.	yersinia enterocolitica was isolated from forty-three surface- and well-water samples and one municipal supply. in many cases these samples were negative for coliform bacteria. after incubation of membrane filters on m-endo agar les at 35 degrees c for total coliform analysis, filters were held an additional 24 h at room temperature. this method was more productive for isolation of waterborne types of y. enterocolitica than was cold enrichment in buffer alone or in combination with modified rapp ...	1978	709433
human blood cholinesterase activity--holland marsh, ontario, 1976.		1978	667390
influenza in a nursing home.		1978	647540
electric kettles as a source of human lead exposure.	five hundred and seventy-four households in ottawa were surveyed to evaluate water boiled in electric kettles as a source of lead exposure. samples of boiled water exceeded the world health organization mandatory limit for drinking water (50 microgram/l) in 42.5% of the households. excessive lead concentrations were observed in 62.8% of water samples from kettles more than 5 years old. multiple regression analysis indicated that age, sex, and cigarette smoking habits, but not lead concentration ...	1978	646460
human tick infestations in ontario: findings at the toronto public health laboratory, 1967-1977.		1977	603862
canadian experience with yersinia enterocolitica (1966--1977).	data pertaining to 1,219 cultures of yersinia enterocolitica isolated in canada are summarized. of the 977 cultures isolated from humans, y. enterocolitica serotype 0:3, biotype 4, phage type ixb was the most predominant type in ontario, quebec and the four eastern provinces. in the western provinces the predominant strains were indol-positive, serotypes 0:8; 5,27 and 4,32. most of the 242 cultures of nonhuman origin, except those isolated from swine and a few isolated from wild animals, were in ...	1979	535372
human facial temperatures in natural and laboratory cold.	asian, european, and american indian men were subjected to craniofacial cooling to determine relative ranking and temperature curves for various facial skin sites. moving and still air 0 degrees c to -35 degrees c in both laboratory and subarctic outdoor settings were used. the objective was to examine resistance to facial frostbite. facial temperatures stabilize well above freezing even under quite cold conditions and this conclusion is congruent with low incidences of facial frostbite. racial ...	1979	454321
familial urinary tract anomalies: association with the major histocompatibility complex in man.	histocompatibility typing of a family with 15 members and a history of ureteropelvic junction stenosis and 4 families with 23 members and a history of vesicoureteral reflux revealed that these anomalies of the urinary tract may be hereditary and segregate with histocompatibility haplotype within a family. thus, a close linkage of childhood reflux and ureteral stenosis with that of the major histocompatibility complex of man is suggested. if confirmed by further family studies it will place the g ...	1979	423332
antimicrobial resistance and resistance plasmids in salmonella from ontario, canada.	collections of 589 human and 204 animal strains of salmonella isolated in ontario during the summer of1974 were examined for susceptibility to 12 antimicrobial agents. many isolates were found to be resistant to both chloramphenicol (12.4% of the human and 38.2% of the animal sample) and ampicillin. the chloramphenicol resistance almost always occurred in strains which were also resistant to ampicillin and was usually due to a self-transmissible plasmid with a resistance pattern of cmkmsmtc (chl ...	1977	332297
antimicrobial susceptibility of salmonella isolates from the broiler chicken industry in ontario.	antibacterial drug resistance among 219 salmonella isolates recovered during 1974 from poultry and poultry environments at the various production stages of broiler chickens in three integrated ontario companies are recorded. all isolates were susceptible to ampicillin, trimethroprim-sulfamethoxazole complex, furazolidone, cephaloridine and amoxicillin. a relative increase in resistance to tetracycline and streptomycin with an accompanying decrease in resistance to triple sulfa compound was recor ...	1977	318909
the prevalence and epidemiology of toxoplasmosis in ontario.	the results of testing 7060 human serum specimens obtained in the province of ontario, canada, were analysed for the presence of antibodies to toxoplasma gondii. of these samples 38% were serologically positive at a titre of 1/16 or greater. the age-specific rates climbed from 2.7% in infants between 6 months and 1 year of age, to about 50% in individuals aged 25 years or over. variations in prevalence were noted between different areas within the province and evidence is put forward to show tha ...	1977	265346
personalized care assures patients' rights.		1975	238881
an immunoprecipitin study of the incidence of influenza a antibodies in animal sera in the ottawa area.	a survey of over 600 'normal' sera from 14 animal species by immunoprecipitin tests in cellulose acetate using viron antigens revealed a high incidence of precipitating activity against a broad range of influenza a virus strains, particularly a2hhong kong/1/68 and /pr8. however, serum treatments trypsin-heat-periodate, naio4, v. cholerae receptor-destroying enzyme (rde), or kaolin eliminated most precipitating activity, which suggests that it was due to "non-specific" inhibitors of influenze vir ...	1975	167931
the occurrence of candida albicans in lake ontario bathing beaches.	there are inherent weaknesses associated with currently used bacterial fecal pollution indicator systems. fecal pollution indicator data would be more meaningful if supplemented with information relating to the occurrence of pathogens in recreational water. through surveys of four bathing beaches on lake ontario, it was established that the opportunistically pathogenic yeast candida albicans occurs in near shore waters. the beaches surveyed could be differentiated on the basis of bacterial fecal ...	1979	120220
chromosome analysis on 930 consecutive newborn children using quinacrine fluorescent banding technique.	chromosome analysing using quinacrine fluorescence was performed on 930 consecutive newborn infants. the total incidence of major chromosome aberrations including numerical changes of the sex chromosomes, and structural changes of autosomes, was 0.54%. incidence of xyy (0.4%) and xxy (0.2%) were relatively higher as compared to other studies. about 0.75% of the newborn infants were found to have a variable bright fluorescent band located on the proximal area of the short arm (p11) rather than on ...	1976	60278