Publications

the neurological manifestations of nipah virus encephalitis, a novel paramyxovirus.	a novel hendra-like paramyxovirus named nipah virus (niv) was the cause of an outbreak among workers from one abattoir who had contact with pigs. two patients had only respiratory symptoms, while 9 patients had encephalitis, 7 of whom are described in this report. neurological involvement was diverse and multifocal, including aseptic meningitis, diffuse encephalitis, and focal brainstem involvement. cerebellar signs were relatively common. magnetic resonance imaging scans of the brain showed sca ...	1999	10482278
update: outbreak of nipah virus--malaysia and singapore, 1999.	during march 1999, health officials in malaysia and singapore, in collaboration with australian researchers and cdc, investigated reports of febrile encephalitic and respiratory illnesses among workers who had exposure to pigs. a previously unrecognized paramyxovirus (formerly known as hendra-like virus), now called nipah virus, was implicated by laboratory testing in many of these cases. febrile encephalitis continues to be reported in malaysia but has decreased coincident with mass culling of ...	1999	10366143
national institute of virology report on testing of virodene by the niv.		1999	10191851
hemorrhagic manifestations and encephalopathy in cases of dengue in india.	thirty-seven serum samples and five serum-csf pairs collected from 42 acutely ill patients admitted to hospitals in maharashtra (bombay, pune and nasik); orissa (raurkela) and south goa were referred to the national institute of virology (niv), pune (maharashtra, india) for serodiagnosis. these patients had clinical manifestations of fever, hemorrhagic manifestations, hepatomegaly, shock syndrome and encephalopathy. sixty-six percent of patients were children below ten years of age. serological ...	1996	9185255
indigenous anti-hepatitis a virus igm capture elisa for the diagnosis of hepatitis a.	anti-hepatitis a virus igm capture elisa was developed by using the reagents produced in the niv laboratory. the major reagents of the assay were anti-human igm antibody, hepatitis a virus (hav) and anti-hav igg-horse radish peroxidase (hrp) conjugate. of these, anti-human igm antibodies were generated in rabbit against igm secreted by human hybridoma clone(g3). hav was derived from buffalo green money kidney cell line infected with hm-175 strain. virus purified from the cell lysates was used fo ...	1994	8088883
antiviral activity of trichothecene mycotoxins (deoxynivalenol, fusarenon-x, and nivalenol) against herpes simplex virus types 1 and 2.	the effect of trichothecene mycotoxins, deoxynivalenol (don), fusarenon-x (fx) and nivalenol (niv), on plaque formation of herpes simplex virus types 1 and 2 (hsv-1 and hsv-2) in hep-2 cells was examined. the 50% effective concentrations (ec50) of don, fx, and niv for hsv-1 plaque formation were 160, 56, and 120 ng/ml, respectively. those for hsv-2 plaque formation were 94, 26, and 50 ng/ml, respectively. these three mycotoxins showed about 2-fold higher selectivity to hsv-2 than to hsv-1. plaqu ...	1995	7494505
evaluation of efficacy of pooled sera in a human immunodeficiency virus antibody prevalence in population surveys.	the pooling of five individual serum samples for the detection of human immunodeficiency virus type 1 (hiv-1) antibodies was examined to assess whether testing pooled versus individual sera was technically feasible. detection of hiv-1 antibodies was performed using a competitive enzyme immunoassay (eia) wellcozyme hiv recombinant commercially available kit. positive, weak positive and negative sera or hiv-1 antibody from wellcozyme hiv recombinant, du pont elisa, serodia hiv mast diagnostica and ...	1990	2223657
tumour incidence, growth, reproduction and longevity in female c3h mice fed polyunsaturated ruminant-derived foodstuffs.	earlier studies with the random-bred quackenbush mouse strain showed that human-type diets based on linoleic acid-enriched foodstuffs derived from ruminants fed protected polyunsaturated oils have no detrimental effects on growth, reproduction or longevity. tumour incidence and time of onset of tumour development have now been studied in the inbred, tumour-prone mouse strain c3h, in addition to growth, reproduction and longevity. mice were fed a polyunsaturated human diet, a conventional human d ...	1979	574381