Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| in vitro susceptibility of fungi to acyclic inhibitors of 2,3-oxidosqualene cyclases. | in the present study we determine the antifungal properties of two acyclic inhibitors of 2,3-oxidosqualene cyclases: 22,23-epoxy-2-aza-2,3-dihydrosqualene (eas) and azasqualene alcohol (asa). fungistatic and fungicidal activity towards dermatophytes and other fungi involved in cutaneous and systemic infections was tested (48 isolates from 10 species). the tests were carried out by inoculating 10 microliters of mycelial homogenate in 1 ml of sabouraud glucose liquid medium containing serial dilut ... | 1996 | 8786759 |
| anti-microbial activity and anti-complement activity of extracts obtained from selected hawaiian medicinal plants. | selected plants having a history of use in polynesian traditional medicine for the treatment of infectious disease were investigated for anti-viral, anti-fungal and anti-bacterial activity in vitro. extracts from scaevola sericea, psychotria hawaiiensis, pipturus albidus and eugenia malaccensis showed selective anti-viral activity against herpes simplex virus-1 and 2 and vesicular stomatitis virus. aleurites moluccana extracts showed anti-bacterial activity against staphylococcus aureus and pseu ... | 1995 | 8786654 |
| fungi responsible for skin mycoses in turin (italy). | there has been a recent increase in the frequency of skin mycoses, coupled with changes in the epidemiology and distribution of the species responsible. periodic epidemiological analyses of these disease are thus required to ensure their efficacious control. hair fragments, skin scrapings, specimens from vesicles and blisters and nail parings were seeded on petri dishes loaded with sabouraud or mycosel agar, supplemented with chloramphenicol and with chloramphenicol plus cycloheximide respective ... | 1996 | 8767009 |
| a study of dermatophytoses in hamadan, the governmentship of west iran. | in order to determine the extent and causative agents of dermatophytoses in the hamadan region of west iran; a study was made during a 9-month period from october 1991 to june 1992. a total of 7495 individuals were studied of whom 681 (9%) were suspect of having cutaneous mycoses. among them dermatophytoses were the commonest infections (259/681 = 38%). of 259 individuals infected with dermatophytes, tinea capitis were observed in 163 (62.9%); t. corporis in 27 (10.4%); t. manuum and t. cruris i ... | 1996 | 8751822 |
| proximal subungual onychomycosis due to microsporum canis. | a case of proximal subungual onychomycosis due to microsporum canis in a 36-year-old woman is presented. the onychomycosis involved the left thumb and the little fingernails, with thinning of the nail plate and crumbling of the nail plate surface. a milky-white discoloration of the proximal portion of the left thumbnail was also evident. a 2-mm longitudinal nail biopsy showed a large number of fungal elements in the whole length of the nail plate. fungal hyphae were more numerous in the ventral ... | 1996 | 8745910 |
| [microsporum canis tinea ciliaris and blepharitis]. | the involvement of eyelashes and eyelids by dermatophytes is unfrequent. | 1995 | 8729822 |
| fungal contamination of the floors of swimming pools, particularly subtropical swimming paradises. | we compared the level of dermatophyte contamination of the floors of traditional swimming pools and of subtropical swimming paradises, a new type of indoor swimming pool introduced in belgium in 1981. from the results of routine hygiene inspections over several years and of a comparative study, we can conclude that the floors of subtropical swimming pools are much more highly contaminated by dermatophytes than the floors of traditional swimming pools. this higher degree of contamination is due t ... | 1995 | 8720205 |
| isolation of keratinophilic fungi from the floors of private veterinary clinics in italy. | to evaluate the presence of keratinophilic fungi in the environment, 400 samples were collected from the floors of 50 private veterinary clinics using 55-mm-diameter 'contact plates', containing mycobiotic agar. after incubation for 15 days at 25 degrees c, the following species were isolated: microsporum canis, trichophyton terrestre, chrysosporium keratinophilum, chrysosporium sp., microsporum gypseum, trichophyton ajelloi, chrysosporium tropicum, trichophyton mentagrophytes, chrysosporium sta ... | 1996 | 8711896 |
| [fungi and yeasts isolated in mycological studies in skin and nail infections in the netherlands, 1992-1993]. | to describe fungi and yeasts isolated from skin and nail infections in the netherlands. | 1996 | 8684495 |
| extracellular enzymatic activity of microsporum canis isolates. | the enzymatic activity of 70 feline and canine microsporum canis isolates was determined by the api-zym test. the liquid phase of cultures, inoculated into tryptic soy broth, was used to examine 19 enzymes. considerable differences were observed among the extracellular enzymatic patterns. all the isolates produced alkaline phosphatase and beta-glucosidase, while lipase (c14), trypsin, chymotrypsin, beta-glucuronidase, and alpha-fucosidase activity was never revealed. esterase (c4) activity was p ... | 1995 | 8684426 |
| [microsporum canis as the origin of an enzootic outbreak in swine. a case report]. | we report on the outbreak of dermatomycosis caused by microsporum canis at a bavarian pig breeding and fattening farm. clinical signs were shown mainly by younger pigs. microsporum canis could be identified in skin scrapings of pigs, cats, and the farmer's daughter by culture and fluorescence microscopy. questions of epizootiology, diagnostics and therapy are discussed. | 1995 | 8585059 |
| epidemiology of dermatophytoses observed in rome, italy, between 1985 and 1993. | between 1985 and 1993, 13,880 patients were studied for possible forms of dermatophytoses. the most frequently isolated dermatophyte was in 2821 positive cases microsporum canis (50%), followed by trichophyton rubrum (27%), trichophyton mentagrophytes (10.6%), epidermophyton floccosum (9.3%), microsporum gypseum (2.3%), trichophyton violaceum (0.6%), trichophyton tonsurans (0.2%) and trichophyton verrucosum (< 0.1%). the genera and species isolated were also considered in relation to the site of ... | 1995 | 8569819 |
| dermatophytes in northern finland in 1982-90. | the epidemiology of human dermatophytes was studied in northern finland in 1982-90. the samples were analysed at the department of medical microbiology, university of oulu. the total number of samples was 17,822, of which 3185 (18%) were positive. the annual number of samples and positive cultures remained relatively constant. trichophyton rubrum was the most common species being isolated from 2101 samples (66% of all positive cultures), while trichophyton mentagrophytes was isolated from 815 sa ... | 1995 | 8569818 |
| production and use of monoclonal antibodies to microsporum canis. | microsporum canis ncpf 179 and m. canis ncpf 177 dermatophyte cytoplasmic extracts (dces) were used as antigens to generate monoclonal antibodies (mabs). hybridomas with supernatants of optical density (od) > 1 for homologous dermatophyte cytoplasmic extracts (ce) and od < 0.5 for heterologous ce of candida albicans tested by the enzyme-linked immunosorbent assays (elisa) were selected for cloning. mabs secreted by cloned hybridoma lines were screened against ce of m. canis, m. gypseum, m. equin ... | 1995 | 8560740 |
| tinea capitis in adults. | invasion of keratin of the hair by dermatophytes is a rare event after puberty. a study of 2200 patients affected by various mycotic cutaneous infections during 6 years of observation brought to our attention three cases of tinea capitis in adults. confirming the studies of other authors, we also found that this disease mostly affected females. in all cases the isolated aetiological agent was microsporum canis, the fungus species most frequently responsible for tinea capitis in italy. | 1995 | 8559199 |
| tinea capitis in the florence area between 1985 and 1993. | this paper describes the main epidemiological findings in 203 patients with tinea capitis and in seven other patients with dermatophytosis that had also extended to the scalp. the patients were observed over a 9-year period (from 1985 to 1993) at the department of dermatology of the university of florence. tinea capitis was the fourth most frequent dermatophytosis. most of the patients were children, although 23 were adults. the most frequent aetiological agent was microsporum canis. it is inter ... | 1995 | 8559198 |
| preliminary screening of some squalenoid derivatives for toxicity towards dermatophytes. | we report a preliminary study of the in vitro anti-dermatophyte activity of six squalenoid derivatives that inhibit 2,3-oxidosqualene cyclase and squalene epoxidase: 2-aza-2,3-dihydrosqualene, 22,23-epoxy-2-aza-2,3-dihydrosqualene, azasqualene alcohol, 19-aza-18,19,22,23-tetrahydrosqualene, 2,3-epoxy-19-aza-18,19,22,23-tetrahydrosqualene and hexafluorosqualene epoxide. the tests were done by inoculating 10 microliters of trichophyton mentagrophytes (robin) blanchard or microsporum canis bodin ho ... | 1995 | 8559196 |
| in vitro antifungal activity of polyporaceae against yeasts and dermatophytes. | the antifungal activity of 38 polyporaceae sensu lato against yeasts and dermatophytes was tested in vitro by the agar dilution method. strains were typed organisms and clinical isolates. in this first report, pycnoporellus fulgens (fr.) donk was found to be the most active species against pathological fungi and showed broad-spectrum antifungal activity against yeasts (candida albicans, candida glabrata) and dermatophytes (trichophyton mentagrophytes, trichophyton rubrum, microsporum canis, micr ... | 1995 | 8559195 |
| dermatophytes from cases of skin disease in cats and dogs in turin, italy. | in urban environments, pet animals such as dogs and cats may be largely responsible for the progressive increase of zoophilic over anthropophilic dermatophytes in the aetiology of human dermatophytoses. mapping, in each city, of the natural foci of zoophilic dermatophytes may thus be important for understanding the epidemiology of human dermatophytoses, and for planning preventive measures. we have surveyed dogs and cats suspected of carrying dermatophytic lesions in the turin area. hairs, skin ... | 1995 | 8531941 |
| uv susceptibility and negative phototropism of dermatophytes. | high doses of ultraviolet radiation (uvr) have well-known inhibitory effects upon dermatophytes. in the present study, the effect of repetitive low doses of uvr on mycelial growth of dermatophytes was tested. pellets of trichophyton rubrum, t. mentagrophytes and microsporum canis were placed between two thin layers of sabouraud glucose agar. obverse, reverse or both sides of these 'sandwich' agars were irradiated for 10 days twice daily with 0.13 or 0.17 j cm-2 uvb. to simulate microaerophilic c ... | 1995 | 8531931 |
| investigations of a killed dermatophyte cell-wall vaccine against infection with microsporum canis in cats. | a laboratory-prepared killed microsporum canis cell-wall vaccine was evaluated under conditions simulating an accidental infection of a cattery, by inoculating eight- to nine-week-old cats with the vaccine or with a placebo control. the vaccinated cats developed high titres of anti-dermatophyte igg as measured by an elisa, and a small cell-mediated response against m canis as measured by a lymphocyte blastogenesis assay, using a whole fungus extract. after being inoculated the cats were challeng ... | 1995 | 8525097 |
| purification, characterization, and lytic activity against naegleria fowleri of two amoebicins produced by bacillus licheniformis a12. | bacillus licheniformis a12 produces two amoebolytic substances (amoebicins a12-a and a12-b) in liquid media during sporulation. both substances have been purified and characterized. they are heat- and protease-resistant peptides containing aspartic acid, glutamic acid, serine, proline, and tyrosine in a molar ratio of 5:2:2:2:2. no fatty acids or carbohydrates have been detected. their molecular weight is 1,430. purified amoebicins a12-a and a12-b exhibit amoebolytic action against naegleria fow ... | 1993 | 8517742 |
| humoral and cellular immune responses to microsporum canis in naturally occurring feline dermatophytosis. | peripheral blood lymphocytes isolated from cattery cats which were culture positive for microsporum canis, or from cats which had recovered from m. canis infection, showed a significantly greater mean in vitro blastogenic response to m. canis antigen than lymphocytes from uninfected cats. mean lymphocyte reactivity to concanavalin a was higher in cats which had recovered from infection than in either culture positive or uninfected cats, whereas reactivity to phytohemagglutinin was highest in the ... | 1993 | 8509949 |
| microsporum canis infection in sheep. | 1993 | 8488650 | |
| ultrastructure of trichophyton violaceum. | the ultrastructure of different fungi have been described in recent literature; however, few reports have concerned dermatophytes. | 1993 | 8440569 |
| the ringworm riddle: an outbreak of microsporum canis in the nursery. | tinea capitis, the most common fungal infection in children, is rare in neonates. we report six patients in a level ii intermediate care nursery who developed nosocomial dermatophyte infections caused by microsporum canis. the investigation, which led to the identification of a nurse as the common source, is described. the nurse had an indolent infection with m. canis. human to human transmission is exceedingly rare for m. canis. the literature regarding neonatal dermatophyte infections is discu ... | 1993 | 8426773 |
| tinea capitis in saudi arabia. | tinea capitis is a dermatophyte infection of the scalp, eyebrows, and eyelashes caused by species of microsporum and trichophyton. the purpose of this study was to discover the incidence and causal agents of tinea capitis in saudi arabia. | 1993 | 8425800 |
| epidemiology of the dermatophytoses in the florence area of italy: 1985-1990. trichophyton mentagrophytes, epidermophyton floccosum and microsporum gypseum infections. | between 1985 and 1990 we observed 2085 cases of dermatophytoses in the florence area of italy. trichophyton rubrum and microsporum canis were the major etiological agents. 126 cases of dermatophytoses observed during this period were caused by trichophyton mentagrophytes. most of the patients came from rural areas or they kept pets. epidermophyton floccosum ranked fourth in frequency (95 cases). the patients were adults and mainly males, most of whom engaged in sports or lived in group environme ... | 1993 | 8413498 |
| oral itraconazole versus topical bifonazole treatment in experimental dermatophytosis. | guinea pigs, infected with either trichophyton mentagrophytes or microsporum canis, were treated orally or topically with azole antifungals daily for two weeks. fungi located in the stratum corneum were affected similarly by both treatment schedules, showing typical cell wall changes after azole exposure and necrosis of internal organelles. fungi located in the hair sheaths were affected only by the oral treatment, which not only prevented invasion of the inner hair structures and inflammatory r ... | 1993 | 8396203 |
| tinea corporis bullosa. | the paper reports a case of tinea corporis bullosa in a 63-year-old woman. near the classical annular lesions on the anterior surface of the left leg, the patient presented frank bullous lesions. serous fluid from the bulla yielded microsporum canis, the first report of the association of this fungus with bullous lesions in tinea corporis. the patient was investigated with routine examinations and immunological studies which showed an intense inflammatory process much greater than in usual cases ... | 1993 | 8366877 |
| [identification of dermatophytes as possible agents in clinically and microbiologically diagnosed dermatophytosis]. | in this study we have investigated the distribution of dermatophyte species clinically and microbiologically on 110 patients with dermatophytosis. the distribution of the dermatophytes according to the localization sites are: tinea capitis 13 (11.8%), t. corporis 12 (10.9%), t. inguinalis 22 (20%), t. pedis et manum 47 (42.7%), t. unguinum 16 (14.5%). the species of dermatophytes which have been cultured were, trichophyton rubrum 32 (29%), t. mentagrophytes 32 (29%), t. schoenleini 4 (3.6%), t. ... | 1993 | 8361407 |
| in vitro susceptibility of dermatophytes to antifungal drugs: a comparison of two methods. | there is an evidence that some fungal strains are resistant to certain antimycotic drugs with resulting therapeutic failures. unlike testing of antibacterial agents, the activity of these drugs against the given fungal strains is not tested routinely. the paper presented is an approach to such a procedure. | 1993 | 8340195 |
| [evaluation of susceptibility of dermatophytes to antifungal drugs]. | a serial dilution and a disc method were used for evaluation of susceptibility of 50 dermatophyte strains belonging to the species trichophyton rubrum, trichophyton mentagrophytes, microsporum canis and epidermophyton floccosum. following drugs were investigated: griseofulvin, pimaricin, clotrimoxazole, miconazole, ketoconazole, biphonazole and naftifin. application of two methods of testing resulted in high convergence of determinations. naftifin was most effective and pimaricin least active. a ... | 1993 | 8309309 |
| [reported frequency of dermatophytes in cats and dogs in austria]. | during four years (1988-1991) 384 skin scrapings and hair samples obtained from cats and 636 samples obtained from dogs in austria were examined routinely for dermatophytes. in cats dermatophytes were isolated or found positive in unstained koh preparation in 50.3% of the samples. 90.7% of these cats were proved to be infected with microsporum canis. trichophyton mentagrophytes was isolated in 5.2% and trichophyton spp. in 2.1% of the positive samples. in dogs dermatophytes were isolated from 12 ... | 1993 | 8306866 |
| humoral immune responses in cats with dermatophytosis. | the igg and igm classes of antibodies to a water-soluble antigen preparation derived from microsporum canis were determined by elisa in the sera of 79 cats with dermatophytosis confirmed by results of fungal culture, and of 46 specific-pathogen-free-derived, barrier-maintained cats with no previous exposure to dermatophytes. of the 79 cats with dermatophytosis, the species isolated were: m canis from 72, m gypseum from 6, and trichophyton mentagrophytes from 1. concentrations of soluble m canis ... | 1993 | 8291765 |
| dermatophytosis of children in kuwait: a prospective survey. | tinea capitis in children is widely reported, whereas there have been only isolated reports on involvement of sites other than the scalp. the purpose of this study was to examine the epidemiological features and treatment responses of dermatophytosis of children in kuwait. | 1993 | 8270336 |
| immunohistological characterization of the cellular infiltrate in dermatophytosis. | the local cell composition of skin infections caused by trichophyton rubrum (13 cases) and microsporum canis (2 cases) was examined using monoclonal antibodies and the abc immunoperoxidase technique. the number of langerhans cells increased both in the epithelium and in the dermis of the mycotic area. apart from these, only t cells were found in the dermis, among which helper cells were predominant. the helper/suppressor ratio showed variations depending upon the pathogen. | 1993 | 8264718 |
| tinea capitis in trinidad. | characteristics of clinically diagnosed cases of tinea capitis from trinidad are described. tinea capitis comprised 29.5% of all dermatophytoses seen at one general hospital out-patient dermatology clinic during a one-year period. males were more often affected than females and there was a predominance of patients of african descent. among the dermatophytes cultured trichophyton tonsurans was the most prevalent (52.9%), followed by microsporum canis (20.0%) and m. audouinii (18.6%). less frequen ... | 1993 | 8254711 |
| increasing importance of trichophyton tonsurans in childhood tinea in new south wales. the pattern of childhood tinea in new south wales, australia 1979-1988: the emergence of trichophyton tonsurans as an important pathogen in tinea capitis in white children. | a retrospective study was undertaken of 192 cases of culture proven tinea capitis occurring between 1979 and 1988 in a predominantly white population of children in new south wales (nsw). the aim of the study was to identify whether trichophyton tonsurans was increasing in importance in the causation of this condition in australia as it was in many other parts of the world. the results of our study were compared with those of earlier australian studies. our study demonstrated that trichophyton t ... | 1993 | 8240189 |
| epidemiological and diagnostic features of canine and feline dermatophytosis in the united kingdom from 1956 to 1991. | between 1956 and 1991, 8349 samples from dogs and cats were received for investigation of suspected dermatophytosis, and 1368 (16 per cent) yielded positive cultures. cats had a significantly higher proportion of positive cultures (26 per cent) than dogs (10 per cent), and of these microsporum canis accounted for 92 per cent in cats and 65 per cent in dogs. the other isolates were diverse but mainly sylvatic dermatophytes, and m gypseum was isolated on only four occasions. different breeds of do ... | 1993 | 8212483 |
| [uncommon caseous maxillary sinusitis of dental origin caused by microsporum canis]. | the authors report an uncommon case of maxillary sinusitis due to microsporum canis. to their knowledge this is the first observation in which a zoophilic dermatophytic fungus which grows usually on keratin has been isolated in a dental maxillary sinusitis in human. this observation makes it possible to discuss nosologic and diagnostic features of dental caseous sinusitis and fungal sinusitis which are often or too often called aspergillosis sinusitis. | 1993 | 8210096 |
| in vitro antifungal activity of essential oils against some isolates of microsporum canis and microsporum gypseum. | 1994 | 8202570 | |
| immunogenicity in guinea-pigs of a crude ribosomal fraction from microsporum canis. | the immunogenicity of a crude ribosomal fraction (crf) extracted from microsporum canis was tested by assessing protection of vaccinated guinea-pigs (gp) against a challenge with the dermatophyte. stimulation of the humoral as well as the cellular immune systems of these animals was evaluated by elisa and the lymphocyte stimulation tests, respectively. in addition, the immune response elicited by the m. canis crf was examined for cross-reactivity towards trichophyton verrucosum antigen. the dura ... | 1994 | 8147094 |
| [incidence of various etiologic agents of superficial mycosis]. | in a retrospective review of laboratory records at the department of mycology, national institute of microbiology "dr. carlos g. malbrán", during the period june 1989-july 1991, 1225 putatively immunocompetent cases of superficial mycoses were identified. ninety five percent of these patients were adults and 5% children. among the total cases, dermatomycoses were caused, 67.6% by dermatophytes, 25.9% by yeasts, 5.9% by malassezia furfur. and 0.5% by other fungi, as proven by the isolation of the ... | 1993 | 8140245 |
| [gum-like exudate from laguncularia racemosa (white mangrove) as culture media for fungi]. | morphological studies of eight species of fungus: aspergillus flavus microsporum canis, epidermophyton floccosum, curvularia lunata, cladosporium carrionii, natrassia mangífera (edo. scytalidium), sporotrix schenckii y rhizophus oligosporus, which belong to families mucedinaceae, dematiaceae and mucoraceae have been carried out in support medium based in gum exudate from laguncularia racemosa (mangle blanco). this native polimer contains galactose, arabinose, rhamnose, uronic acid and proteins. ... | 1993 | 8123711 |
| microsporum canis scalp ringworm: its primary or secondary ectothrix character. | this study supports the view that, in cases of tinea capitis due to a microsporum canis infection, ectothrix arthroconidium formation is extrapilary and arises from intrapilary hyphae. the hyphae of m. canis perforate and digest the hair cuticle to alter its appearance from a normally identifiable structure of imbricated cells with a distal free border, to a grossly altered and pathological layer. conidium production mainly takes place outside the hair shaft and forms thick clusters between the ... | 1993 | 8108682 |
| ecology and epidemiology of dermatophyte infections. | our knowledge of ecology and epidemiology of dermatophytes and the factors influencing their transmission has helped us understand better the natural history of dermatophytoses. it seems that the anthropophilic agents of scalp infection are being eradicated in developing nations. the exception is trichophyton tonsurans-related tinea capitis in north america. microsporum canis is a prevalent agent of tinea capitis in many regions of the world, and this could be related to close association of hum ... | 1994 | 8077503 |
| microsporum canis infection of the thumb-nail. | 1994 | 8033403 | |
| dermatophytes and dermatophytoses in the milan area between 1970 and 1989. | between 1970 and 1989 we examined 13,019 patients with dermatophytoses in the milan area, northern italy. the results obtained during the 1980-89 period were compared with those obtained in the years 1970-79. from the data collected, tinea corporis emerged as the most frequently observed dermatophytosis, followed by tinea pedis and unguium. as far as dermatophytes are concerned, the dermatological pattern is dominated by microsporum canis and trichophyton rubrum. other species, such as epidermop ... | 1993 | 8015563 |
| itraconazole versus griseofulvin in the treatment of tinea capitis: a double-blind randomized study in children. | tinea capitis is a fungal infection in which topical therapy is often unsuccessful. griseofulvin has been considered to be a first-line therapy. other antifungal agents are the azole derivatives. among these, itraconazole was compared with griseofulvin in children in a double-blind study. | 1994 | 8002149 |
| [exoenzymes of dermatophytes isolated from acute and chronic tinea]. | the presence of five enzymes (deoxyribonuclease, elastase, lipase, caseinase and hemolysin) in 76 strains of dermatophytes 47 of trichophyton rubrum, 10 of t. mentagrophytes, five of t. tonsurans, 10 of microsporum canis and four of epidermophyton floccosum) isolated from 30 cases of acute dermatophytosis and from 46 chronic ones was determined by a qualitative plate assay; in the same way, the presence of these five enzymes with the acute and chronic dermatophytosis was correlated. it was obser ... | 1994 | 7938939 |
| dermatophytoses in iran. | a total of 12,150 cases of suspected dermatophytoses in different areas of iran were studied between 1986 and 1991. the age groups most commonly infected were 1-9 and 20-29 years. clinical diagnosis was confirmed in only 9345 cases by laboratory examination. of these positive samples, 1633 cases were found to be positive by direct microscopic observation only, 429 by culture only and 7283 by both techniques. scalp ringworm of children was the most common type of tinea. but according to the rate ... | 1994 | 7935592 |
| enzyme patterns of dermatophytes. | exoenzymes produced by common dermatophytes, in addition to their ability to cause cutaneous inflammation, are thought to contribute to fungal spread. to investigate the patterns of enzymes released by common dermatophytes as well as scopulariopsis brevicaulis, the fungi were grown in liquid media containing either hair, stratum corneum, neopeptone or lipids, or in rpmi medium. enzymes recovered from the culture supernatants were compared using the api-zyme test. as a result, the widest range of ... | 1994 | 7935585 |
| fungicin m4: a narrow spectrum peptide antibiotic from bacillus licheniformis m-4. | the strain bacillus licheniformis m-4 produces a 3.4 kda hydrophilic peptide with antifungal activity, named fungicin m4. analysis of the purified peptide shows that it contains the amino acids glu (8), arg (5), pro (4), tyr (8), val (3), met (2) and orn (4). its inhibitory spectrum is restricted to microsporum canis cect 2797, mucor mucedo cect 2653, mucor plumbeus ccm 443, sporothrix schenckii cect 2799, bacillus megaterium and corynebacterium glutamicum cect 78. fungicin m4 exerts biocidal ac ... | 1994 | 7928782 |
| human dermatophyte-responsive t-cell lines recognize cross-reactive antigens associated with mannose-rich glycoproteins. | resistance to dermatophyte infections has been shown to be mediated in part by t lymphocytes. the dermatophyte antigens recognized by human t lymphocytes and their degree of cross-reactivity were analyzed. dermatophyte-responsive t-cell lines were generated by in vitro sensitization to crude fungal extracts obtained from trichophyton rubrum, trichophyton tonsurans, microsporum canis and epidermophyton floccosum. proliferation was measured by incorporation of 3h-thymidine. the human t-cell lines ... | 1994 | 7921653 |
| fungal infections in the netherlands. prevailing fungi and pattern of infection. | species of fungi have specific characteristics in geographic distribution, and they have a predilection for certain body areas. | 1995 | 7894094 |
| tinea capitis in south wales--observations in change of causative fungi. | we report an observed change in the causative organisms in 45 consecutive cases of tinea capitis seen in the cardiff area over the last 9 years. direct microscopy using potassium hydroxide was positive in all but one case, but this was subsequently positive on culture. this retrospective analysis shows that more cases are being seen in our department, and that a higher proportion of cases are due to trichophyton violaceum whereas previously we would have expected the majority of cases to be due ... | 1994 | 7889666 |
| antifungal activity of itraconazole and terbinafine in human stratum corneum: a comparative study. | the evaluation of antifungal agents by in vitro and animal experiments cannot predict clinical efficacy with certainty. new models are needed to assess and compare antifungal activity. | 1995 | 7868711 |
| antidermatophytic activity of allylamine derivatives. | the allylamine derivatives are a new class of synthetic antifungal agents. the antidermatophytic activity of the two main compounds, naftifine and terbinafine were compared in vitro with those of ketoconazole and itraconazole by agar dilution. eighty eight clinical isolates of dematophytes comprising of microsporum canis (50), m. audouinii (5), trichophyton rubrum (6) t. mentagrophytes (5), t. violaceum (12), t. simii (5), t. verrucosum (1), t. soudanense (1), t. erinacie (1) and epidermophyton ... | 1994 | 7868170 |
| microsporum canis vaccine. | 1994 | 7852169 | |
| polymerase chain reaction-based detection of dermatophyte dna with a fungus-specific primer system. | there is significant clinical interest in primers which are specific for fungi and do not hybridize to dna of other eukaryotes or prokaryotes. such primers would allow specific amplification of fungal dna from human tissue samples containing fungi. fungal identification to the species level could follow by direct sequencing or restriction analysis. several previously described primer systems cross-react with dna of plants and animals. we have designed a primer system that amplifies a fragment of ... | 1994 | 7845424 |
| microsporum canis infection in a 5-year-old boy: transmission from the interior of a second-hand car. | microsporum canis is one of the most common zoophilic dermatophytes. if transmitted to humans, inflammatory lesions may develop, e.g. on the scalp. m. canis was isolated from a 5-year-old boy living in a suburban area who suffered from a long-standing, mildly inflammatory lesion on the scalp that had been treated for several months with anti-eczematous regimens. there had been no contact with animals, e.g. cats or dogs, in the previous months, but the lesions had developed a few weeks after the ... | 1994 | 7845421 |
| [the occurrence of keratinolytic fungi in the polluted environment of the labedy district in gliwice]. | this study was undertaken to find relationships between the degree of bacteriological contamination with qualitative composition of potentially pathogenic keratinolytic fungal population in soil, sediment and air samples from the labedy district in gliwice (poland). the examined soil samples were characterized by the predominance of botryotrichum piluliferum, chrysosporium anamorph of arthroderma curreyi, myceliophthora anamorph of ctenomyces serratus, chrysosporium pannicola and trichphyton aje ... | 1994 | 7792523 |
| antidermatophytic activity of garlic (allium sativum) in vitro. | interest in herbal medicine is enjoying a renaissance at present. garlic (allium sativum) is an intriguing herb with a long history of medicinal use for a variety of diseases including ringworm infections. | 1995 | 7790146 |
| sds-page separation of dermatophyte antigens, and western immunoblotting in feline dermatophytosis. | water-soluble antigens liberated from the disrupted mycelium of nine dermatophytes (seven isolates of microsporum canis, one each of microsporum gypseum and trichophyton mentagrophytes) were compared by analytical slab sds-page. no substantial differences were observed between the protein bands of the m. canis isolates, but certain distinctive bands were apparent in the other two species examined. western immunoblotting using m. canis-derived antigens separated by sds-page was used to investigat ... | 1994 | 7777039 |
| isolation and physico-chemical characterization of an antifungal and antibacterial peptide produced by bacillus licheniformis a12. | an antifungal substance named peptide a12-c has been purified to homogeneity from supernatants of sporulated cultures of bacillus licheniformis a12. it consists of a 0.77-kda hydrophilic peptide containing two residues of glu and one of arg, ala, pro, tyr and orn. no fatty acids, phosphorus or carbohydrates have been detected. peptide a12-c is active on several fungi (microsporum canis cect 2797, mucor mucedo cect 2653, m. plumbeus (ccm f 443, sporothrix schenckii cect 2799 and trichophyton ment ... | 1993 | 7763922 |
| onychomycosis caused by microsporum canis: treatment with itraconazole. | 1995 | 7751453 | |
| failure of clotrimazole-betamethasone dipropionate cream in treatment of microsporum canis infections. | 1995 | 7751452 | |
| [spread of a microsporum canis infection in an agricultural facility (case description)]. | in a combined pig production and fattening unit the weaned piglets on the flatdecks and some young fattening pigs were suffering from a microsporum canis-infection. besides the pigs the children of the farmer showed skin alterations. the infection was spread probably by the cats, which had access to the houses for sows and for sows with piglets. in cases of uncertain skin alterations, a mycologic etiology should be considered. | 1994 | 7717960 |
| experimental microsporum canis infection in cats: correlation between immunological and clinical observations. | microsporum canis infection was induced in five of six adult cats by the application of mycelium to shaved and mildly abraided skin. the clinical course of the disease was monitored over 16 weeks by physical examination and wood's lamp illumination. the incubation period (time from inoculation to first appearance of infected hairs) varied between 8 and 13 days and was followed by a progressive phase of slow peripheral expansion of lesions accompanied by scaling, alopecia and skin thickening that ... | 1995 | 7666298 |
| [interspecific outbreaks of dermatomycoses +caused by microsporum canis and microsporum gypseum]. | dermatomycosis in domestic animals are important zoonosis in view of the fact that they maintain close contact with human beings. seven ringworm outbreaks are here described, one of m. gypseum involving a cat and a women and the remainder of m. canis involving 20 human beings (adults, young people and children), 5 dogs, 16 cats and a gibbon-monkey (hylobates lar). | 1994 | 7660034 |
| successful treatment of griseofulvin-resistant tinea capitis in infants. | we report on three siblings, children of a farmer, aged 3-8 years, suffering from tinea capitis due to microsporum canis. initially, the infection was treated systemically with griseofulvin as well as externally for 5 months without success. therapy was changed to itraconazole 33 mg per day orally. laboratory investigations followed every 4-6 weeks. dependent on the dose per kg body weight the children were cured clinically after 2-5 months and microbiologically after 5-8 months. thus, itraconaz ... | 1994 | 7659136 |
| experimental immunity to microsporum canis and cross reactions with other dermatophytes of veterinary importance. | an inactivated, broad-spectrum dermatophyte vaccine was used to produce an active immunity in guinea-pigs against microsporum canis. none of the vaccinates developed infection from a contact exposure challenge that produced clinical infections in 70% of the unvaccinated controls. infection with m. canis induced antibody titres (elisa) and delayed cutaneous hypersensitivity (dch) reactions to itself as well as cross-reacting titres to trichophyton equinum and t. mentagrophytes and dch reactions t ... | 1995 | 7658308 |
| fungal cultures on cyanoacrylate skin surface strippings as a dose-finding method for topical antifungals. a placebo-controlled study with 0.25% and 0.50% itraconazole cream. | the antimycotic activities of 0.25% and 0.50% itraconazole cream were compared in the stratum corneum after once-daily applications for 1 week. two groups of 12 healthy volunteers applied either itraconazole or placebo on the inner side of each forearm, in a double-blind design. cyanoacrylate skin surface strippings (csss) were taken on days 8, 11 and 21. conidia or yeasts of selected fungi (trichophyton rubrum, trichophyton metagrophytes, microsporum canis and candida albicans) were deposited o ... | 1995 | 7658304 |
| trichophyton rubrum as the causative agent of tinea capitis in three children. | tinea capitis, which is caused by trichophyton rubrum, is only rarely described in medical literature. incidence of this disease appears to lie well below 1% in europe. microsporum canis, trichophyton mentagrophytes and trichophyton tonsurans are the predominant causative agents discussed here. in april 1993 t. rubrum was isolated from typical pathological changes to the capillitium area in three children from a nigerian family, who had been living in germany for 3 years. all three children reve ... | 1995 | 7637688 |
| evaluation of topical therapies for the treatment of dermatophyte-infected hairs from dogs and cats. | seven commonly used, topical antifungal products (i.e., lime sulfur, chlorhexidine, captan, povidone-iodine, sodium hypochlorite, and enilconazole solutions, and ketoconazole shampoo) were evaluated for their antifungal activity on microsporum canis-infected hairs from dogs and cats in an in vitro study. hairs were soaked or shampooed in each product for five minutes twice a week for four weeks. of the seven products used in this study, lime sulfur and enilconazole solutions were superior in inh ... | 1995 | 7634061 |
| semiquantitative study of tinea capitis and the asymptomatic carrier state in inner-city school children. | to quantify and characterize the asymptomatic carrier state of tinea capitis in school children from the inner city. | 1995 | 7630681 |
| [changes in the fungal spectrum of dermatomycoses]. | the spectrum of aetiologic agents isolated from 3607 patients suspicious for dermatomycosis being in the care of the berlin charité clinics was analysed. identification of dermatophytes and moulds were performed conventionally. for the identification of yeasts biochemical and genetic methods were used. among the dermatophytes in comparison of present with previous incidence rates changes can be observed. opportunistic yeasts are recognized in increasing importance. five fungal species are formin ... | 1995 | 7630368 |
| antimicrobial activity of cassia alata from malaysia. | ethanolic extract of cassia alata leaves was investigated for its antimicrobial activities on several microorganisms including bacteria, yeast, dermatophytic fungi and non-dermatophytic fungi. in vitro, the extract exhibited high activity against various species of dermatophytic fungi but low activity against non-dermatophytic fungi. however, bacterial and yeast species showed resistance against in vitro treatment with the extract. the minimum inhibitory concentration (mic) values of the extract ... | 1995 | 7623478 |
| sertaconazole in the treatment of pediatric patients with cutaneous dermatophyte infections. | sertaconazole is a new topical anti-mycotic with demonstrated efficacy against dermatophyte infections in adults. an open-label, multicenter study was conducted to assess the efficacy and tolerability of sertaconazole in children in primary care. twenty-nine children were initially included in the study and tolerability was assessed in all of them. the 16 children examined for efficacy (8 girls and 8 boys, aged 2 to 16 years) all had culture-confirmed cutaneous mycoses. fourteen children had tin ... | 1995 | 7614526 |
| inability of two topical treatments to influence the course of experimentally induced dermatophytosis in cats. | an experimental model of dermatophytosis was used to compare the efficacy of 2 topical antifungal treatments against microsporum canis infection in cats. infection was established in 24 cats by topical application of 10(5) m canis macroconidia to the skin of the lateral part of the abdomen under an occlusive bandage. three groups of 6 cats each then were treated twice weekly for 18 weeks with chlorhexidine shampoo and dip, detergent shampoo vehicle only, or glyceryl monolaurate shampoo. six cats ... | 1995 | 7601693 |
| antibacterial, antidermatophytic and antitoxigenic activities of onion (allium cepa l.) oil. | the inhibitory effect of onion oil against the growth of various isolates of bacteria representing gram-positive (4 isolates) and gram-negative (4 isolates) species were studied. results show that onion oil was highly active against all gram-positive bacteria tested and only one isolate (klebsiella pneumoniae) of gram-negative bacteria. the inhibitory effect of onion oil against nine different species of dermatophytic fungi were also studied. onion oil (200 ppm) completely inhibited the growth o ... | 1995 | 7600010 |
| efficacy of griseofulvin and itraconazole in the treatment of experimentally induced dermatophytosis in cats. | to evaluate the efficacy of itraconazole and griseofulvin in the treatment of microsporum canis infection, 15 juvenile cats were infected by topical application of 10(5) live m canis macroconidia to the skin of the lateral part of the trunk, and an occlusive bandage was applied. after 3 weeks, cats were randomly assigned to 1 of 3 treatment groups (n = 5 each): cats in the first group received griseofulvin (50 mg/kg of body weight, po, q 24 h); the second group received itraconazole (10 mg/kg, p ... | 1995 | 7591941 |
| an outbreak of dermatophytosis in pigs caused by microsporum canis. | an outbreak of dermatophytosis caused by microsporum canis in a porcine farm is described. the morbidity was 100% among sows, 95% among new-borns and 75% among feedlot animals. microsporum canis was also isolated from walls and environmental air. | 1995 | 7544873 |
| the occurrence of dermatophytes in slovakia. | we have compared the epidemiology of dermatophytoses in slovakia during the periods 1956-85 and 1986-92. infections caused by trichophyton rubrum gradually increased while infections due to trichophyton verrucosum and microsporum canis decreased. | 1995 | 7477094 |
| screening of hundred rwandese medicinal plants for antimicrobial and antiviral properties. | a series of 100 rwandese medicinal plants (267 plant extracts), used by traditional healers to treat infections, were screened for antibacterial, antifungal and antiviral properties. the results of the testing showed that 45% were active against staphylococcus aureus, 2% against escherichia coli, 16% against pseudomonas aeruginosa, 7% against candida albicans, 80% against microsporum canis and 60% against trichophyton mentagrophytes. not less than 27% of the plant species exhibited prominent ant ... | 1995 | 7475121 |
| ascocarp production by nannizzia otae on keratinous and non-keratinous agar media and mating behavior of n. otae and 123 japanese isolates of microsporum canis. | 1980 | 7464901 | |
| experimental infection of goats and guinea pigs with microsporum canis and trials on treatment with canesten cream and neguvon solution. | goats and guinea pigs were found to be quite susceptible to infection with the bovine strain of microsporum canis. the severe and characteristic annular lesions seen in goats suggested the suitability of this species as a model for future research. the lesions in both goats and guinea pigs are described in details. trials on treatment of the experimentally induced lesions with 1% canesten cream and 6% neguvon solution were attempted. the efficacy of the drugs used were assessed on the basis of c ... | 1980 | 7464898 |
| natural focus of microsporosis caused by microsporum canis bodin. | the authors discovered a natural focus of microsporosis caused by the dermatophyte microsporum canis bodin. an adult man and four children were afflicted by this dermatophytosis. symptomatic and inapparent forms of the disease in the focus were also detected in several cats and dogs. homeless cats were found to be the source of the causative agent and its permanent hosts. a chainlike transmission from these cats was triggered to home-kept cats and dogs and to family members of their owners. both ... | 1980 | 7450609 |
| keratinophilic fungi on four animal groups. | four surveys were conducted on different animal groups in the metropolitan area of perth. microsporum canis was the only fungus isolated from cats and was prevalent in these animals. dermatophyte infections in dogs were less common and were caused by m. canis. m. gypseum and trichophyton mentagrophytes. t. mentagrophytes was isolated from laboratory guinea pigs but not from native animals. | 1980 | 7436952 |
| fungal infections of the scalp in western australia. | between 1963 and 1972, 1,212 fungi were isolated from patients with tinea capitis (ringworm of the scalp) in western australia. the clinical diagnosis was confirmed by microscopic examination examination and/or culture of hairs, scale or pus. microsporum canis, a zoophilic fungus, was found to be the most common agent of tinea capitis in western australia, causing 1,100 infections and accounting for 90.8% of the total isolates. the highest incidence of m. canis infections occurred in children be ... | 1980 | 7434132 |
| etiology of ringworm of the scalp, beard and body in rome, italy. | from 1972 to 1977 the authors examined 1,311 patients in rome affected by ringworm of the scalp, beard and body, comparing their findings with a study made in milan between 1969 to 1973 and with earlier italian studies from 1900 to date. it appears that at the beginning of the century scalp ringworm was usually caused by trichophyton violaceum and t. tonsurans, whereas microsporum canis was rarely found. today the trichophyton species are rarely isolated, whereas microsporum species, particularl ... | 1980 | 7423332 |
| incidence of dermatophytes in the san francisco bay area. | a total of 1,101 patients was studied for the incidence and distribution of dermatophytes in the san francisco bay area from 1974 to 1978. 267 dermatophytes were isolated and identified. trichophyton rubrum and trichophyton tonsurans were the most prevalent dermatophytes. t. rubrum caused 83% of tinea pedis, 82% of tinea unguium, 80% of tinea manuum and 66% of tinea cruris. t. tonsurans was the major cause of tinea capitis (60%) followed by microsporum canis. microsporum audouinii was not encoun ... | 1980 | 7398991 |
| the dysgonic form of microsporum canis in n.w. london. | an account is given of the occurrence in n.w. london of ringworm due to the dysgonic form of microsporum canis in cats, dogs, and humans. the unusual morphology of the dysgonic strain is described as is the extraordinary lability of the fungus in culture. the distribution of cases in man and animals in the area is mapped. the clinical and epidemiological behaviour of the fungus, as illustrated by four family outbreaks, differs little from that of the typical strain. the origin of the dysgonic st ... | 1980 | 7387885 |
| [kerion-like tinea barbae caused by microsporum canis (author's transl)]. | 1980 | 7383055 | |
| studies on fungal flora in hair from domestic and laboratory animals suspected of dermatophytosis. i. dematophytes. | hairsamples of domestic and laboratory animals suspected of dermatophytosis were examined for the presence of dermatophytes. a nutritionally poor base-medium developed by the author was successfully used in the isolation and identification of dermatophytes. casein-medium supplemented with vitamins and sabouraud-liquid medium were used in special cases. dermatophytes were isolated in 36 of 331 samples (10.9%). the dermatophytes recovered were microsporum canis: 13 isolates from cat. 4 from dog. 1 ... | 1980 | 7376879 |
| lipolytic activity of some dermatophytes. | the lipolytic activities of four common dermatophytes, epidermophyton floccosum, microsporum canis, trichophyton mentagrophytes and t. rubrum, were tested on agar medium supplemented with one or other of several lipids. the lipolytic activity was estimated by comparison of the zone sizes around the colonies. the highest lipolytic activity was demonstrated by m. canis, followed by t. mentagrophytes and e. floccosum; t. rubrum virtually lacked lipolytic activity. the clinical importance of these o ... | 1980 | 7359572 |
| superficial mycoses in the west of scotland. | ringworm formed almost 70 per cent of all superficial mycoses diagnosed. the feet and nails were most frequently affected and a single species, trichophyton rubrum was responsible for the majority of infections that required specialist attention. scalp ringworm which, until the middle of this century, was the most common form of the disease now constitutes only 5 per cent of infections and the majority of these are caused by the zoophilic fungus microsporum canis. the anthropophilic dermatophyte ... | 1981 | 7313682 |
| a study of skin diseases in dogs and cat. vii. ringworm infection. | during 1973 through 1979 a total of 774 specimens from dogs and 227 specimens from cats were submitted for examination for ringworm infection. ninety-six (12.4%) of the samples from dogs and 66 (29.1%) of the samples from cats were positive by culture (tables i and ii). microsporum canis accounted for all infections in cats and for 95.8% of the infections in dogs. four dogs (4.2%) were infected with trichophyton mentagrophytes. three fourths of the infections with m. canis were diagnosed during ... | 1981 | 7312586 |
| [microsporous infection of the scalp in an adult (author's transl)]. | infection of the scalp in an elderly woman due to microsporum canis (zoophilic, long-lived fungus) after repeated direct contact with infected cats. we think that the infection could occur because of an age-induced decrease in some of the organic functions which govern the healing process of microsporous infections during puberty. | 1981 | 7262386 |