Publications

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relations between synthesis of deoxyribonucleotides and dna replication in 3t6 fibroblasts.in exponentially growing 3t6 cells, the synthesis of deoxythymidine triphosphate (dttp) is balanced by its utilization for dna replication, with a turnover of the dttp pool of around 5 min. we now investigate the effects of two inhibitors of dna synthesis (aphidicolin and hydroxyurea) on the synthesis and degradation of pyrimidine deoxynucleoside triphosphates (dntps). complete inhibition of dna replication with aphidicolin did not decrease the turnover of pyrimidine dntp pools labeled from the ...20143921544
canine brucellosis in a household.three cases of canine brucellosis from the same household were discovered during a serosurvey of privately owned dogs. one dog was found to be seropositive and culture-positive, 1 dog was seropositive, and 1 dog had suspect test results, with eye lesions suggestive of brucella canis infection. all dogs had signs seen with b canis infection, but none was pathognomonic. although pathologic findings in 2 of the dogs were consistent with findings reported by other investigators, none was conclusive ...19853921503
immunocytochemical localization of carbonic anhydrase in the spinal cords of normal and mutant (shiverer) adult mice with comparisons among fixation methods.the peroxidase-antiperoxidase technique was used for immunocytochemical localization of carbonic anhydrase in the mouse spinal cord to detect whether this antigen was normally present in myelinated fibers, in oligodendrocytes in both white and gray matter, and in astrocytes, and to determine where the carbonic anhydrase might be localized in the spinal cords of dysmyelinating mutant (shiverer) mice. the most favorable methods for treating tissue were: 1) immersion in formalin-ethanol-acetic acid ...19853917467
[can the present-day physician be surpassed?]. 20133914761
[alpine skiing accidents. study of 7103 patients treated at the monthey district hospital (vs), from 1974 to 1983]. 20143911339
the kindling phenomenon and a clinical application: the procaine test. 20143911234
the sfia11 mutation prevents filamentation in a response to cell wall damage only in a reca+ genetic background.n-alpha-palmitoyl-l-lysyl-l-lysine dihydrochloride ethyl ester (pll) at sublethal doses causes filamentous growth of e. coli strains except sfia mutants, which divide normally in its presence. pll does not elicit the sos responses as judged by lambda prophage induction, an increase of reca protein synthesis or induction of the sfia operon in a sfia::lacz fusion strain. thus, it appears that filamentation caused by pll is not an sos function and might be the result of membrane damage by pll, whic ...19853911030
application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer.fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. these flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. i ...20143901789
gov. john ashcroft talks with the msma about medical issues. interview by c. c. swarens. 20143900689
the pulmonary circulation in children with congenital heart disease: morphologic and morphometric considerations. 20143896433
expression of a melanoma-tumor-associated antigen as demonstrated by a monoclonal antibody (d6.1) in cytopathologic preparations of human tumor cells from effusions and needle aspirates.immunocytopathologic studies were performed on 79 fine needle aspiration biopsies (fnabs) and effusions from 13 melanomas and 57 other human neoplasms with the monoclonal antibody (mab) d6.1 raised against a partially purified melanoma-tumor-associated antigen (mtaa). the purposes of these studies were (1) to evaluate the ability of mab 6.1 to react with melanoma cells in cytopathologic preparations and (2) to define the spectrum of reactivity of mab d6.1 in cytopathologic preparations of non-me ...19853890654
usefulness of postoperative enzymes for diagnosis of perioperative myocardial infarction following aortocoronary bypass. 20133879714
regulation of the production of granulocyte-macrophage colony-stimulating factor by macrophage-like tumour cell lines.macrophage tumour cell lines (pu5-1.8, p388d1) produced detectable granulocyte macrophage colony-stimulating (csf-2) activity measured using a factor-dependent cell line fdc-p1. the production of csf-2 was enhanced by endotoxin and inhibited by serum, and correlated inversely with [3h]tdr incorporation. mrna isolated from pu5-1.8 or p388d1 cells initiated csf-2 production when injected into xenopus laevis oocytes. the specific activity in this assay was unaltered in mrna isolated from endotoxin- ...19853871405
[a longitudinal study of dental caries prevalence of "h" primary school children in choong-chung-book-do]. 20133869191
[proposal for a new anesthetic method in ambulatory dentistry]. 20133867598
[proposal for a new anesthetic method in ambulatory dentistry]. 20133867598
the correlation of temporomandibular joint sounds with joint morphology in fifty-five autopsy specimens.joint sounds from 55 fresh temporomandibular joint autopsy specimens were correlated with the macroscopic examination of joint morphology. fifty-eight per cent of the joints were silent. two thirds of these showed normal superior disc positions and remodeled articular surfaces, whereas one third exhibited anterior disc displacement. twenty per cent of the joints elicited clicking and showed anterior disc displacement. twenty-two per cent of the joints elicited crepitation and exhibited mostly ar ...20133855989
[patients' use of the buzzer calling a nurse]. 20133848607
[venous ulcer? arterial ulcer?]. 20133848073
the kock continent ileal reservoir: an alternative to the conventional urostomy. 20133844015
radiological demonstration of healing in paget's disease of bone treated with apd.twenty-three patients with paget's disease received the bisphosphonate apd and were examined radiologically every 6 months. because routine roentgenographic procedures were followed, a number of the x rays were not fit for comparison. the radiographic technique, as well as the positioning of the patients, is critical since both could lead to artefacts. all patients reached normal biochemical levels, usually within 6 months. out of the 23 patients 11 showed definite radiological improvement in on ...20113842289
[the occurrence of sexually transmitted diseases in northern zuid-holland; epidemiological information for the organization of their prevention]. 20133840232
atracurium in clinical anaesthesia: effect of dosage on onset, duration and conditions for tracheal intubation.conditions for tracheal intubation at 90 seconds, time to onset of maximum block and duration of clinical relaxation after five different doses of atracurium, which ranged from 0.4 to 1.0 mg/kg were studied in 200 adult patients who were anaesthetized with nitrous oxide, oxygen and halothane or fentanyl. the conditions for intubation improved significantly with increasing doses, and were acceptable in 55% patients with a 0.4 mg/kg dose and in about 90% of those who received the two higher doses. ...20133839980
saving the world. 20133837959
shigellosis in children--prevalence of subgroups and antibiotic resistance. 19853836974
hepatitis b virus and primary liver cancer on chongming island, people's republic of china.data on potential risk factors for primary liver cancer (plc), including hepatitis b virus (hbv) infection, contaminated drinking water, maize consumption, and use of tobacco and alcohol were collected from 12,222 males over 40 years of age living on chongming island, a high-risk area for plc. during the first 3 years of follow-up (1980-82), 70 deaths from this disease occurred among study subjects. preliminary results indicate that hbv carriers were 6.7 times more likely to die of plc than were ...19853834335
[the professional education of the librarian-information specialist in italy. references in the biomedical field]. 20123827018
the place and value of bestophilia in perversions.an attempt is made to place bestophilia in cultural, clinical, and theoretical perspective. archeological and anthropological documentation and records of the widespread appearance in mythology of this practice are cited. this archaic form of perversion is still practiced in rural environments and isolated communities. the treatment of a man who grew up in such an environment gave the author the opportunity to study this form of perversion. the correlation of clinical findings with culturally sa ...19863819310
arthroplasty of the elbow. twenty years' experience of a new approach.we report the use of a new approach for elbow arthroplasty in 58 cases over a 20-year period. a wide exposure, obtained by elevating the triceps attachment and dividing the radial collateral ligament, allows the excision of diseased tissue, articular irregularities and osteophytes. normal anatomy is restored and active mobilisation can be started 10 days after operation. good or fair results, with over 70 degrees of joint movement, were achieved in 88% of cases.20133818716
trends in gastric cancer sex ratio in the united states.recent reports have suggested that the male/female ratio for gastric cancer has decreased over time and that the mean age of cases has increased. the authors calculated age- and sex-specific mortality rates for gastric cancer from 1950 through 1979 for whites using data from us vital statistics and population estimates from the us census bureau. whereas sex ratios based on crude mortality rates showed a decrease over time from 1.7 in 1950 to 1.5 in 1979, similar ratios based on age-adjusted mort ...20113815262
exercise thallium imaging in patients with diabetes mellitus. prognostic implications.we used exercise thallium 201 imaging in 123 patients with diabetes mellitus (77 men and 46 women, aged 56 +/- 8 years), 75% of whom had angina pectoris (typical or atypical). during exercise testing, 18 patients (15%) had angina pectoris, 28 (23%) had ischemic st changes, and 69 (56%) had abnormal thallium images. during follow-up (up to 36 months), there were 12 cardiac events; four patients died of cardiac causes and eight had nonfatal acute myocardial infarction. univariate and multivariate ...20133813750
[changes in the estrous cycle of the rat after irradiation with a helium-neon laser]. 19863812911
[vacuous chewing after haloperidol and gaba-linoleamide administration in the rat]. 19863812899
[vacuous chewing after haloperidol and gaba-linoleamide administration in the rat]. 19863812899
[control of diabetes in the peroperative period using continuous intravenous insulin infusion with a pump]. 20133811779
[rare neoplastic and common pathologies of the thyroid].observation of three cases of rare thyroid pathology (medullary carcinoma, thyroid lymphoma, de quervain's subacute thyroiditis) triggers a discussion of the need to take due account of such rare pathologies in preoperative differential diagnosis in order to avoid giving the wrong treatment. the fact that extemporary histological examination is no help in such situations is also discussed.20133808388
[procedures in fulminant courses of necrotizing enterocolitis].14/42 neonates suffering from n.e.c. developed the clinical stage iii (intestinal necrosis, septicemia) and/or iv (intestinal perforation, peritonitis) within 24-48 h ("fulminant" course). 2/14 deteriorated dramatically and died before operation. in 12/14 cases, the general condition could be improved and immediate laparotomy was performed (2/12 died). management and factors affecting prognosis are discussed. following surgery, there was no significant difference in survival rates between "fulmi ...20133807587
[changes and induction of drug-metabolizing enzymes in rats with hepatic injuries]. 19863804171
[optico-structural machine analysis of the nuclear chromatin and cytoplasmic sh-groups of epitheliocytes of the oral mucosa of healthy subjects and in peptic ulcer of the stomach and duodenum].by means of optico-structural machine analysis, epitheliocytes of mucous membrane of the oral walls have been studied in 21 healthy persons and in 30 persons suffering from ulcerous disease of the stomach and duodenum. changes in densitometric parameters of epitheliocytic nuclei at the ulcerous disease demonstrate increasing amount of heterochromatin and, hence, increasing degree of cell differentiation. changes in contents and distribution of sh-groups in cell cytoplasm indicate that keratin is ...20133800670
[prevention of stress ulcers with cimetidine and ranitidine. comparative studies within the scope of cardiosurgical interventions].2 h2-receptor antagonists--cimetidine and ranitidine--were applied in our prospective randomized study in 100 cardio-surgical cases in order to test their therapeutical efficiency for the prophylaxis of bleedings of gastroduodenal stress-ulcers. during the phase of the intensive therapy of 2 days the patients of group a received t.i.d. 400 mg of cimetidine i.v. and those of group b twice a day 150 mg of ranitidine i.v. the following tests were realized: gastric acidity, plasma level, side-effect ...20133798932
adolescent fertility and childbearing trends among hispanics in texas. 20133798377
psychological dimensions of distress in chronic pain patients: a factor analytic study of symptom checklist-90 responses. 20133794030
neurotoxicity caused by lithium-verapamil synergism. 20133793965
water structure in vitamin b12 coenzyme crystals. i. analysis of the neutron and x-ray solvent densities.the disordered solvent distribution in crystals of vitamin b12 coenzyme was examined using the methods of high-resolution neutron and x-ray diffraction. one set of neutron (0.95 a) and two sets of x-ray (0.94 and 1.1 a) data were collected and the resulting models were extensively refined using least-squares and fourier syntheses. the solvent regions were analyzed in two stages: first, main sites were assigned to the well defined regions of solvent density and refined using least squares; second ...20133790696
qt interval revisited. 20133788797
treatment of vascular headaches. 20133781835
interactive responses to diethylstilboestrol in c3h mice.female c3heb/fej mice were fed diethylstilboestrol (des) at a dietary concentration of 100 ppb beginning at 6 wk of age. several oestrogen-sensitive target organs (uterus, vagina, bone and mammary gland) were removed and examined histologically when mice died, became moribund, were killed at scheduled intervals or were removed because of presumptive mammary tumours (palpable mass having a 1-cm diameter). oestrogen-sensitive histological observations for which there was less than a 100% prevalenc ...19863781439
nucleic acid binding drugs--xiv. the crystal structure of 1-methyl amsacrine hydrochloride; relationships to dna-binding ability and anti-tumour activity.the crystal structure of the 1-methyl derivative of the anticancer drug amsacrine [4'-(acridin-9-ylamino)-3'-methoxy-methanesulphonanilide+ ++] as its hydrochloride salt has been determined. the compound crystallizes in the monoclinic space group p21/n with cell dimensions a = 15.302(3), b = 8.035(2), c = 18.258(4) a and beta = 102.68(2) degrees, and has been refined to a final r of 0.055. the acridine chromophore is significantly non-planar, with a butterfly conformation about the c(9)-n(11) bo ...20133778515
the intercostal artery in kawasaki disease. a pathologic study of 17 autopsy cases.two hundred twenty-seven arteries from 17 autopsy patients having a history of kawasaki disease were studied histopathologically and immunohistologically. forty-five arteries in four cases (duration of illness ranging from 23 to 33 days) showed an arterial lesion characterized by reactive proliferative change of the medial smooth-muscle cells and frequent aneurysmal dilation. the lesion was mostly localized to the proximal portion. the intercostal arterial lesions were similar to those in the co ...20133778140
toward the elimination of guessing bias in landolt acuity testing.a subjective guessing bias has been claimed to be present in association with visual acuity testing using the classic circular landolt ring. a semiautomated visual test system has been described previously which uses an angular version of the broken ring. evidence is presented here which indicates that this version of the test object overcomes the problem of guessing bias and thus might prove to be not only a preferred "standard" or reference optotype but also an acceptable clinical optotype in ...20133777112
[mediastinal dislocation accentuated by initiation of pleural drainage]. 20133775925
[from the national socialist time]. 20133774763
in vivo stability of in vitro labelled 99tcm-red blood cells for radionuclide determination of left ventricular ejection fractions and volumes.serial determination of radionuclide left ventricular ejection fraction and volumes require a label that remains highly stable after introduction into the human circulation. we have evaluated the in vivo stability of 99tcm-red blood cells (99tcm-rbc) labelled in vitro by preparation with small amounts of a stannous agent in 19 patients with coronary artery disease. the distribution volume of 99tcm-rbc was virtually identical to that of rbc labelled with 51cr. labelling efficiency expressed as th ...19863774253
[quadrantectomy. choice therapy for 23 clinical cases of t1 carcinoma in situ of the breast]. 20093774180
[quadrantectomy. choice therapy for 23 clinical cases of t1 carcinoma in situ of the breast]. 20093774180
comparison of in-the-ear and over-the-ear hearing aid fittings.a custom in-the-ear (ite) hearing aid fitting was compared to two over-the-ear (ote) hearing aid fittings for each of 9 subjects with mild to moderately severe hearing losses. speech intelligibility via the three instruments was compared using the speech intelligibility rating (sir) test. the relationship between functional gain and coupler gain was compared for the ite and the higher rated ote instruments. the difference in input received at the microphone locations of the two types of hearing ...20133773492
assessment of the hemodynamic response to single passive head up tilt by non-invasive methods in normotensive subjects.the hemodynamic response to passive upright tilt in thirty-five normal subjects was assessed by combined electrocardiography, differentiated electrical impedance cardiography, phonocardiography and non-invasive blood pressure measurement. the increase in transthoracic impedance and decrease in estimated stroke volume were accompanied by a cardio-acceleratory and vasopressor response. the increase in heart rate did not compensate for the decrease in estimated stroke volume and the estimated cardi ...20123762269
training the helpers. 20133760697
[concentration of anti-brain antibodies in the blood of patients with diffuse toxic goiter and thyrotoxic encephalopathy].the content of anticerebral antibodies was studied in the peripheral blood of 10 healthy persons, 42 patients with diffuse toxic goiter and 25 patients with thyrotoxic encephalopathy. it was determined by a method of passive hemagglutination using a human brain protein extract as an antigen. in the healthy persons antibodies to cerebral antigens were undetectable whereas in 24 of 42 patients with diffuse toxic goiter without signs of the nervous system involvement they were detected (log2 titer- ...19863754967
computer assisted neuron searching.a microprocessor controlled driver for the kopf hydraulic microdrive is described. neuron searching parameters can be specified during an experiment to facilitate the search for active neurons. these parameters include: period between movements, numbers of microns of electrode movement/advance, depth of penetration, automatic cessation of advancement when activity is encountered, and slow or rapid rates of movement. in addition, analog voltage outputs are available that are proportional to impul ...20133753955
[mixed fractures of the posterior wall of the acetabulum. value of x-ray computed tomography].the authors have studied three cases of fracture of the posterior wall of the acetabulum in which one fragment was separated and another was impacted. the nature of the lesions were not able to be appreciated on standard radiographs but was visualised by means of tomodensitometric studies. the patients were treated surgically to obtain an accurate reconstruction of the articular surface. the importance of tomodensitometry in the diagnosis of such lesions is stressed.20133749555
[surgical approach to abdominal aortic aneurysm with malignant alimentary tract tumor: report of three cases].the clinical courses of three cases with various alimentary tract malignant lesions coincidental with abdominal aortic aneurysm were reported. of those three patients, a simultaneous resection of the malignant lesion and aneurysm was carried out in two patients, while an secondary abdominal aneurysmectomy following the resection of the malignant lesion was done in one patient. a 70-year-old man with cancer of the cecum and an infra-renal abdominal aneurysm, was diagnosed preoperatively, and a si ...19863747994
identification of 5,9-hexadecadienoic acid in the marine sponge chondrilla nucula.the fatty acid 5,9-hexadecadienoic was identified in the sponge chondrilla nucula. this is the shortest fatty acid with the delta 5,9 unsaturation yet isolated from a marine sponge.20123747742
lepromin skin test in normal people in singapore--a one-year follow up. 20133746045
recurrent atypical intussusception caused by ileal gastric ectopia simulating hirschsprung's disease. 20133744512
[results of the secondary cataract peeling method in posterior chamber lenses]. 20133744230
amodiaquine and hepatitis. 20133740693
effect of tick-borne fever on the disposition of sulphadimidine and its metabolites in plasma of goats.the effect of tick-borne fever (tbf) on the plasma disposition of sulphadimidine (sdm) and its metabolites in goats was studied. in uninfected goats, sdm was extensively metabolised mainly by hydroxylation, glucuronidation and to a minor extent by acetylation. in tbf infected goats the hydroxylation of sdm into 6-methylhydroxysulphadimidine (sch2oh) as well as into 5-hydroxysulphadimidine (soh) was markedly reduced (-57.6 and -63.6 per cent, respectively). an unidentified metabolite (metabolite ...19863738235
[diagnosis and treatment of hepatic hematomas in pre-eclampsia]. 20133736165
[diagnostic and prognostic value of determining serum gastrin level in the treatment of patients with gastric polyps]. 20133735932
salvage of angioaccess after late thrombosis of radiocephalic fistulas for hemodialysis.a retrospective study of 44 surgical procedures performed in 39 patients with late occlusions of radiocephalic fistulas for hemodialysis is reported. in 6 cases (13.6%) no apparent anatomical cause was found, and a simple thrombectomy was performed as a corrective procedure. some sort of arterial and/or venous stenosis was present in the other 38 cases. in 11 cases with evidence of mild localized vascular stenosis we performed a thrombectomy and then an endoluminal angioplasty with a balloon cat ...20103733357
3,3',5'-triiodothyronine inhibits iodothyronine-5'-deiodinating activity induced by 3,5,3'-triiodothyronine at equimolar concentrations in cultured fetal mouse liver.to investigate the rt3 effect on iodothyronine-5'-deiodinating activity (i-5'-da) in cultured fetal mouse liver, liver on the 19th day of gestation, in which little or no i-5'-da was detected and, therefore, rt3 was very stable, was cultured in medium containing thyroid hormone-depleted fetal calf serum supplemented with cortisol, insulin, and various concentrations of iodothyronines. after 4-15 days of culture, i-5'-da in the homogenate was assessed by the amount of iodide released from outer r ...19863732155
[autonomic disturbance in cerebellar degeneration--a comparative study between olivopontocerebellar degeneration and late cortical cerebellar atrophy]. 20133731629
[air pollutants of indoor air with reference to the status in smog weather conditions]. 20133726476
acute steroid-induced tetraplegia following status asthmaticus.a 10-year-old girl was treated for an acute asthmatic attack with ventilation and a high-dose steroids regimen. an areflexic paralysis of the four limbs was noted when artificial ventilatory support was withdrawn. electromyography and a muscle biopsy revealed marked myopathic features. we discuss the unusual presentation of an acute steroid-induced myopathy in an asthmatic patient.20133725482
[various methods of the practical evaluation of functional possibilities of implanted synchronous cardiostimulators].some clinical device for the assessment of the sensitivity of the implanted demand-type cardiostimulator to bioelectric potentials are described. a relationship is demonstrated between the perception of bioelectric noise (muscular potentials) and sensitivity of the cardiostimulator.20133712949
reevaluation of the role of gangliosides as receptors for tetanus toxin.binding of tetanus toxin to rat brain membranes was of lower affinity and capacity when binding was determined in 150 mm nacl, 50 mm tris-hcl (ph 7.4) than in 25 mm tris-acetate (ph 6.0). binding under both conditions was reduced by treating the membranes with neuraminidase. pronase treatment, however, reduced toxin binding only in the tris-saline buffer (ph 7.4). in addition, the concentration of gangliosides required to inhibit toxin binding was 100-fold higher in tris-saline compared to tris- ...19863711900
reciprocal functional interaction of adjacent myocardial segments during regional ischemia: an intraventricular loading phenomenon affecting apparent regional contractile function in the intact heart.the mechanism of the increase in function in myocardial segments adjacent to those subjected to regional ischemia is not known. to investigate the hypothesis that changes in regional loading are an important causative factor of this phenomenon, 17 dogs were instrumented with segmental shortening sonomicrometers in the left anterior descending and circumflex artery distributions, circumflex coronary flow probes and cuff occluders, as well as circumflex coronary pressure catheters. additionally, t ...19863711491
reciprocal functional interaction of adjacent myocardial segments during regional ischemia: an intraventricular loading phenomenon affecting apparent regional contractile function in the intact heart.the mechanism of the increase in function in myocardial segments adjacent to those subjected to regional ischemia is not known. to investigate the hypothesis that changes in regional loading are an important causative factor of this phenomenon, 17 dogs were instrumented with segmental shortening sonomicrometers in the left anterior descending and circumflex artery distributions, circumflex coronary flow probes and cuff occluders, as well as circumflex coronary pressure catheters. additionally, t ...19863711491
structural and functional relationships of grafted vasopressin neurons.fetal vasopressin neurons were grafted into adult long-evans rats with vasopressin deficiencies created by neural lobe ablation one week prior to implantation. control animals and recipients with ectopic grafts still possessed significant deficits in fluid regulation 6 weeks following implantation. however, recipients with grafts fused to the host median eminence and containing magnocellular vasopressin neurons juxtaposed to the host portal vasculature showed restored peripheral vasopressin acti ...19863708331
[mallory-weiss syndrome in systemic scleroderma]. 20133695303
barium embolisation during barium enema examination. 20133690174
[important now to have a vision for a new and better education]. 20133686430
the measurement of foot preference.foot preference has been given only superficial attention in studies of hemispheric lateralization, although it has potential utility for predicting hemispheric dominance. this paper reports the development of a reliable (alpha = 0.89) 11-item behavioral inventory of foot preference. since footedness and handedness are only partially related, both must be measured reliably to identify individuals who have a consistent right or left side preference. it has yet to be determined whether footedness ...20133683814
[psychogenic depression in involution. social medicine significance]. 20133683678
the duck hepatitis b virus pre-c region encodes a signal sequence which is essential for synthesis and secretion of processed core proteins but not for virus formation.analysis of the serum of duck hepatitis b virus (dhbv)-infected ducks has revealed the presence of c-terminally truncated viral core proteins (e antigens). these proteins are glycosylated and therefore were not released from infected cells by lysis but rather by active secretion, indicating that the dhbv core protein can be synthesized alternatively as a cytoplasmic or a secretory protein. transient expression of cloned wild-type dhbv dna and of a specifically designed viral mutant in a human he ...19873682059
the duck hepatitis b virus pre-c region encodes a signal sequence which is essential for synthesis and secretion of processed core proteins but not for virus formation.analysis of the serum of duck hepatitis b virus (dhbv)-infected ducks has revealed the presence of c-terminally truncated viral core proteins (e antigens). these proteins are glycosylated and therefore were not released from infected cells by lysis but rather by active secretion, indicating that the dhbv core protein can be synthesized alternatively as a cytoplasmic or a secretory protein. transient expression of cloned wild-type dhbv dna and of a specifically designed viral mutant in a human he ...19873682059
[problems in realizing the results of medical research in practice]. 20113677150
family ties. 20133673873
a comparison of girls and boys with teacher-identified problems of attention. 20133667500
the long-term effects of a token economy on safety performance in open-pit mining.a token economy that used trading stamps as tokens was instituted at two dangerous open-pit mines. employees earned stamps for working without lost-time injuries, for being in work groups in which all other workers had no lost-time injuries, for not being involved in equipment-damaging accidents, for making adopted safety suggestions, and for unusual behavior which prevented an injury or accident. they lost stamp awards if they or other workers in their group were injured, caused equipment damag ...20133667473
[a method of quantitative determination of delta 5,7-sterols in unsaponifiable lipid fractions].the technique is offer for rapid quantitative definition of sterols having a system of delta 5,7-conjugated double bonds which conditions biological activity of d vitamin--the result of photoisomerisation of the sterols. the technique bases on the analysis of uv absorption spectra of unsaponifiable lipid fraction of several kinds of mutant yeast strains and the model mixtures of sterols. the results obtained concerning the estimation of delta 5,7-sterols containing in total fraction are confirme ...19873658928
[reconstructive plastic surgery of the humeral condyles following removal of endoprostheses of the elbow versus arthrodesis].the condyles of the elbow are of utmost importance for the stability of this joint. this is particularly evident in cases where elbow prostheses had to be removed because of loosening or infection and where the condyles had been deliberately resected at the primary operation. in order to obtain a functional elbow with sufficient stability and mobility after removal of the prostheses, we can reconstruct the condyles by means of a large autologous bone graft, which we take from the midpart of the ...20133658417
[pars plana vitrectomy in diabetics with advanced complications in other organs]. 20133652150
[longevity]. 20123642160
[i stopped smoking without suffering. interview by france métivier]. 20133641660
[the work conditions of the instructors at midwifery schools in japan]. 20133639981
the vulnerable elderly. 20133639104
["death" and nursing education. clinical training in dealing with dying patients and their families and responses to nursing students]. 20133637398
[high dosage methotrexate--pharmacokinetic surveillance and role of the nursing team]. 20123635240
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