Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| synthesis of p-triazinylphosphonium salts--hybrid molecules with potential antimicrobial activity. | the new hybrid drugs combining in a single molecule triazine ring attached to phosphonium salt were prepared and their bactericidal activity against gram-positive bacteria staphylococcus aureus atcc43300 (mrsa - methycyline resistant staphylococcus aureus strain) two gram-negative bacteria escherichia coli ccug31997 serotype o153 (epec - enteropathogenic escherichia coli strain), proteus mirabilis 1784 (mdr - multidrug resistant clinical strain) were determined using microdilution method. | 2011 | 21648193 |
| isolation, selection and biodegradation profile of phenol degrading bacteria from oil contaminated soil. | in the present study, an aerobic bacterial strains ocs-a and ocs- b were isolated from an oil contaminated soil. the strains were identified to be citrobacter freundi and proteus mirabilis according to morphological, physiological and biochemical characteristics. the strains were able to degrade about 90% of 100 mg/l phenol within 80 h as sole carbon and energy source. the lag phase increased with increase in phenol concentration. determination of metabolic intermediate 2-hms, was done which ind ... | 2011 | 21643832 |
| recognition of dna by the helix-turn-helix global regulatory protein lrp is modulated by the amino terminus. | the asnc/lrp family of regulatory proteins links bacterial and archaeal transcription patterns to metabolism. in escherichia coli lrp regulates approximately 400 genes, over 200 of them directly. in earlier studies, lrp genes from vibrio cholerae, proteus mirabilis, and e. coli were introduced into the same e. coli background, and yielded overlapping but significantly different regulons. these differences were seen despite amino acid sequence identities of 92% (vibrio) and 98% (proteus) to e. co ... | 2011 | 21642464 |
| setting interpretive breakpoints for antimicrobial susceptibility testing using disk diffusion. | antimicrobial susceptibility testing plays a key role in clinical microbiology. the disk diffusion test dates back to the 1940s and became standardised from the 1950s, with the international collaborative study (ics) and national committee for clinical laboratory standards (nccls) as the two major standards. interlaboratory variation of disk test results was recognised early but has never been dealt with in a satisfactory manner. the error-rate bounded method was described in 1974 and its role i ... | 2011 | 21640560 |
| superior in vitro activity of ertapenem and piperacillin/tazobactam against recent clinical isolates of proteus mirabilis from intra-abdominal infections (smart 2009-2010). | 2011 | 21632217 | |
| molecular analysis of ndm-1-producing enterobacterial isolates from geneva, switzerland. | objectives to analyse the mechanisms responsible for decreased susceptibility or resistance to carbapenems in several enterobacterial isolates recovered in 2009-10 in geneva university hospitals, switzerland. methods pcr and sequencing were used to identify β-lactamases, 16s rna methylases and plasmid-mediated quinolone resistance genes. the transferable properties of the plasmids were analysed, as well as their plasmid type. the strains were typed by multilocus sequence typing. results three pa ... | 2011 | 21628303 |
| new delhi metallo-ss-lactamase-1: local acquisition in ontario, canada, and challenges in detection. | new delhi metallo-ß-lactamase-1 (ndm-1) is a recently identified metallo-ß-lactamase that confers resistance to carbapenems and all other ß-lactam antibiotics, with the exception of aztreonam. ndm-1 is also associated with resistance to many other classes of antibiotics. the enzyme was first identified in organisms isolated from a patient in sweden who had previously received medical treatment in india, but it is now recognized as endemic throughout india and pakistan and has spread worldwide. t ... | 2011 | 21624908 |
| potentiation of antimicrobial activity of ciprofloxacin by pelargonium graveolens essential oil against selected uropathogens. | the recent approach of using herbs and antibiotics in combination constitutes a strategy to overcome the problems of resistance and side effects associated with conventional antibiotics. in the present study, the antimicrobial effect of pelargonium graveolens l' hér essential oil in combination with ciprofloxacin was evaluated on uropathogens, namely, klebsiella pneumoniae kt2, proteus mirabilis prt3 and staphylococcus aureus st2. minimum inhibitory concentrations of p. graveolens essential oil ... | 2011 | 21618302 |
| a novel compound from the marine bacterium bacillus pumilus s6-15 inhibits biofilm formation in gram-positive and gram-negative species. | biofilm formation is a critical problem in nosocomial infections and in the aquaculture industries and biofilms show high resistance to antibiotics. the aim of the present study was to reveal a novel anti-biofilm compound from marine bacteria against antibiotic resistant gram-positive and gram-negative biofilms. the bacterial extract (50 μg ml(-1)) of s6-01 (bacillus indicus = mtcc 5559) showed 80-90% biofilm inhibition against escherichia coli, shigella flexneri, proteus mirabilis and s6-15 (ba ... | 2011 | 21614700 |
| screening of australian plants for antimicrobial activity against campylobacter jejuni. | campylobacter jejuni is the most common cause of acute enteritis in humans, with symptoms such as diarrhoea, fever and abdominal cramps. in this study, 115 extracts from 109 australian plant species were investigated for their antimicrobial activities against two c. jejuni strains using an in vitro broth microdilution assay. among the plants tested, 107 (93%) extracts showed activity at a concentration between 32 and 1024 µg/ml against at least one c. jejuni strain. seventeen plant extracts were ... | 2011 | 21604309 |
| in vitro antimicrobial activity of ten medicinal plants against clinical isolates of oral cancer cases. | abstract: background: suppression of immune system in treated cancer patients may lead to secondary infections that obviate the need of antibiotics. in the present study, an attempt was made to understand the occurrence of secondary infections in immuno-suppressed patients along with herbal control of these infections with the following objectives to: (a) isolate the microbial species from the treated oral cancer patients along with the estimation of absolute neutrophile counts of patients. (b) ... | 2011 | 21599889 |
| n-substituted aminomethanephosphonic and aminomethane-p-methylphosphinic acids as inhibitors of ureases. | small unextended molecules based on the diamidophosphate structure with a covalent carbon-to-phosphorus bond to improve hydrolytic stability were developed as a novel group of inhibitors to control microbial urea decomposition. applying a structure-based inhibitor design approach using available crystal structures of bacterial urease, n-substituted derivatives of aminomethylphosphonic and p-methyl-aminomethylphosphinic acids were designed and synthesized. in inhibition studies using urease from ... | 2011 | 21559954 |
| identity gene expression in proteus mirabilis. | swarming colonies of independent proteus mirabilis isolates recognize each other as foreign and do not merge together whereas apposing swarms of clonal isolates merge with each other. swarms of mutants with deletions in the ids gene cluster do not merge with their parent. thus ids genes are involved in the ability of p. mirabilis to distinguish self from non-self. here we have characterized expression of the ids genes. we show that idsabcde and f are transcribed as an operon, and we define the p ... | 2011 | 21551301 |
| improved detection of ampc β-lactamases in escherichia coli, klebsiella pneumoniae, and proteus mirabilis using new susceptibility breakpoints for third-generation cephalosporins. | 2011 | 21549542 | |
| antimicrobial resistance in urinary tract pathogens in canada from 2007 to 2009: canward surveillance study. | from january 2007 to december 2009 an annual canadian national surveillance study (canward) tested 2943 urinary culture pathogens for antimicrobial susceptibilities following clinical and laboratory standards institute (clsi) guidelines. the most frequently isolated urinary pathogens (n, % of all isolates) were escherichia coli (1581, 54%), enterococci (410, 14%), klebsiella pneumoniae (274, 9%), proteus mirabilis (122, 4%), pseudomonas aeruginosa (100, 3%), and staphylococcus aureus (80, 3%). r ... | 2011 | 21537027 |
| identifying patients harboring esbl-producing enterobacteriaceae on hospital admission: derivation and validation of a scoring system. | increases in community-acquired infections caused by extended-spectrum β-lactamase (esbl)-producing enterobacteriaceae have important implications for hospital infection control and empirical antibiotic therapy protocols. we developed and validated a tool for identifying patients harboring these organisms at hospital admission. we retrospectively analyzed chart data for 849 adult inpatients. the derivation cohort included 339 patients admitted to a large rome hospital during 2008, with (n=113) o ... | 2011 | 21537020 |
| lactobacillus fermentum isolated from human colonic mucosal biopsy inhibits the growth and adhesion of enteric and foodborne pathogens. | a number of lactobacillus species are used as probiotic strains in order to benefit health. we have isolated l. fermentum from human colonic mucosal biopsy samples that possess antimicrobial activities against entroinvasive and foodborne pathogens such as escherichia coli, salmonella paratyphi a, shigella sonnei, staphylococcus aureus, enterococcus faecalis, proteus mirabilis, pseudomonas aeruginosa, and vibrio sp. in addition to lactic acid, l. fermentum secretes antimicrobial proteinacious com ... | 2010 | 21535608 |
| gram-negative bacillary meningitis in egypt. | gram-negative bacillary meningitis (gnbm) is a rare disease with a high rate of mortality. | 2011 | 21527836 |
| xanthogranulomatous pyelonephritis. | abstract xanthogranulomatous pyelonephritis is an uncommon chronic destructive granulomatous process of renal parenchyma in association with long-term urinary tract obstruction and infection. it affects females more often than males, with a wide range of age, from newborn to elderly. almost all patients are symptomatic and the most common symptoms are flank or abdominal pain, lower urinary tract symptoms, fever, palpable mass, gross hematuria, and weight loss. the common laboratory findings are ... | 2011 | 21526966 |
| inhibition of development, swarming differentiation and virulence factors in proteus mirabilis by an extract of lithrea molleoides and its active principle (z,z)-5-(trideca-4',7'-dienyl)-resorcinol. | antibacterial activity of lithrea molleoides extract against proteus mirabilis has been previously reported by our group. in the present study, the compound (z,z)-5-(trideca-4',7'-dienyl)-resorcinol (1) was isolated as its responsible active principle. the effects of the compound obtained and of l. molleoides extract on p. mirabilis growth and virulence factors were evaluated. compound 1 showed mic and mbc values of 4000μg/ml. it was found that the extract, at four times the mic, produced comple ... | 2011 | 21514124 |
| transcriptome of proteus mirabilis in the murine urinary tract: virulence and nitrogen assimilation gene expression. | the enteric bacterium proteus mirabilis is a common cause of complicated urinary tract infections. in this study, microarrays were used to analyze p. mirabilis gene expression in vivo from experimentally infected mice. urine was collected at 1, 3, and 7 days postinfection, and rna was isolated from bacteria in the urine for transcriptional analysis. across 9 microarrays, 471 genes were upregulated and 82 were downregulated in vivo compared to in vitro broth culture. genes upregulated in vivo enc ... | 2011 | 21505083 |
| synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections. | chitosan and nanoparticle silver are both materials with demonstrated antimicrobial properties and have been proposed singly or combined as constituents of antimicrobial burn dressings. here we show that they combine synergistically together to inhibit the in vitro growth of gram-positive methicillin-resistant staphylococcus aureus (mrsa) and gram-negative bacteria (pseudomonas aeruginosa, proteus mirabilis and acinetobacter baumannii) as judged by bioluminescence monitoring and isobolographic a ... | 2011 | 21502618 |
| identification of bacteria isolated from nasal polyps and their ability to produce superantigens and biofilms in lebanese patients. | staphylococcus aureus superantigens and bacterial biofilms have been implicated in the development of chronic rhinosinusitis and nasal polyps. we conducted a study of 32 lebanese patients-21 males and 11 females, aged 15 to 71 years (mean: 39)-to identify bacteria isolated from nasal polyps and to determine if these bacteria produced superantigens and biofilms. polyps were surgically removed, homogenized, and subjected to bacteriologic studies. the presence or absence of s aureus enterotoxin a, ... | 2011 | 21500161 |
| potential use of 68ga-apo-transferrin as a pet imaging agent for detecting staphylococcus aureus infection. | (67)ga citrate has been extensively used to detect infection and inflammation since 1971. however, its clinical utility is compromised due to several limitations. the present project explored whether (68)ga-apo-transferrin ((68)ga-tf), when prepared in vitro, is a useful agent for positron emission tomography (pet) imaging of bacterial infection. | 2011 | 21492788 |
| [cmy-2-type plasmid-mediated ampc ß-lactamases emerging in tucumán, argentina]. | in the last years, enterobacteriaceae such as klebsiella pneumoniae, proteus mirabilis and escherichia coli, have acquired resistance to third-generation cephalosporins (c3g) because of the presence of plasmid-mediated ampc ß-lactamases. the aim of this work was to detect plasmid ampc enzymes and to investigate the predominant types in our region. between march and july 2009, 733 consecutive isolates of enterobacteriaceae derived from hospitals and outpatient centers were studied. susceptibility ... | 2011 | 21491062 |
| phytochemical screening and antibacterial activities of vernonia ambigua, vernonia blumeoides and vernonia oocephala (asteraceae). | some vernonia species (vernonia ambigua, vernonia blumeoides and vernonia oocephala) used in northern nigerian traditional medicine, were subjected to phytochemical screening using standard procedures. the antibacterial activity using the disc diffusion method as outlined by the nccls was carried out on klebsiella pneumoniae, streptococcus pyogenes, staphylococcus aureus, corynbacterium ulcerans, methicillin resistant staphylococcus aureus (mrsa), salmonella typhi, pseudomonas aeruginosa, shigel ... | 2011 | 21485703 |
| cold atmospheric plasma: a successful treatment of lesions in hailey-hailey disease. | 2011 | 21482888 | |
| inhibition of inos reduces the therapeutic effects of ozone in acute necrotizing pancreatitis: an in vivo animal study. | abstract objective. previously, it was shown that ozone and s-methylthiourea (smt) treatments had ameliorative effects on experimental models of acute necrotizing pancreatitis (anp). it is possible that the combination of ozone and smt may be more effective than either therapy. therefore, we investigated the efficacy of combination therapy with ozone and smt in an experimental rat model of anp. material and methods. sprague-dawley rats were divided into five experimental groups. groups were desi ... | 2011 | 21463160 |
| urine cultures from indwelling bladder catheters in nursing home patients: a point prevalence study in a swedish county. | abstract objectives. to survey the bacterial flora and antibiotic resistance in urinary strains from patients with indwelling bladder catheters residing in nursing homes within a geographically defined region. material and methods. urine was sampled for culture from 163 catheter patients (126 men and 37 women) during a 2 week period in march 2010. susceptibility testing of the isolated bacteria was compared with all urinary strains (n = 9994) from hospitals and primary healthcare in the same geo ... | 2011 | 21452928 |
| [practice management of chronic bacterial prostatitis with levofloxacin]. | the aim of this prospective observational study was to present relevant data on the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis (nih-ii) in the daily clinical routine of urologists in their practices. in total, 243 patients were treated, including 62 patients with a microbiologically confirmed diagnosis -based on expressed prostatic secretion (eps). the current evaluation is based on these patients. their median age was 53 years. the patients were treate ... | 2011 | 21445824 |
| re: strategy to control catheter encrustation with citrated drinks: a randomized crossover study. a. khan, f. housami, r. melotti, a. timoney and d. stickler. j urol 2010; 183: 1390-1394. | 2011 | 21439588 | |
| epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum +¦-lactamase production in proteus mirabilis bacteremia. | we evaluated the clinical features of ciprofloxacin-resistant proteus mirabilis bacteremia and risk factors for ciprofloxacin resistance. | 2011 | 21437168 |
| [antimicrobial susceptibility of clinical isolates of aerobic gram-negative bacteria in 2006]. | we determined mics of antibacterial agents against 1280 clinical strains of aerobic gram-negative bacteria (19 genus or species) isolated at 16 japanese facilities in 2006. mics were determined using mostly broth microdilution method and antibacterial activity was assessed. strains producing extended-spectrum beta-lactamases (esbl) accounted for 3.7% of escherichia coli, 2.7% of klebsiella spp., and 11.4% of proteus spp. notably, 18.8% of proteus mirabilis was found to produce esbl higher than 1 ... | 2010 | 21425597 |
| monitoring of multiple drug-resistant pathogens in a selected stretch of bay of bengal, india. | the present work aims at identification of multiple drug-resistant pathogenic bacteria in a selected stretch, namely, puri on the bay of bengal, india. six stations at the coast of puri were selected and samples of water and sediment were collected during the winter of 2008 and 2009 for this study. thirty-eight pathogenic bacteria were isolated and identified from both the water and the sediment of 6 fixed stations (pu-1a, pu-1b, pu-2, pu-3, pu-4, and pu-5). the identified pathogens were escheri ... | 2011 | 21424669 |
| antibiotic susceptibility pattern of urinary tract pathogens in ibadan, nigeria. | urinary tract infections (uti) affect all age groups and occur in both hospitalized and non-hospitalized individuals and have serious impact on the socioeconomic life of the individual and the society, and also account for a large proportion of antibacterial drug consumption. treatment failure has been attributed to increasing resistance to common antibiotics, but there is paucity of data from this part of nigeria. this prospective study was carried out to determine the prevalence and antibiotic ... | 2010 | 21416786 |
| nasal immunization with attenuated salmonella typhimurium expressing an mrpa-tetc fusion protein significantly reduces proteus mirabilis colonization in the mouse urinary tract. | the development of effective strategies to prevent urinary tract infections (utis) has become an important goal in public health. proteus mirabilis is commonly associated with complicated utis and expresses several virulence factors, including mannose-resistant proteus-like (mr/p) fimbriae. here, a fusion protein formed from mrpa, the structural protein of mr/p fimbriae, and tetc, a non-toxic but highly immunogenic fragment of tetanus toxin, to be delivered by an attenuated salmonella typhimuriu ... | 2011 | 21415205 |
| evolution and spread of a multidrug-resistant proteus mirabilis clone with chromosomal ampc-type cephalosporinases in europe. | proteus mirabilis isolates obtained in 1999 to 2008 from three european countries were analyzed; all carried chromosomal ampc-type cephalosporinase bla(cmy) genes from a citrobacter freundii origin (bla(cmy-2)-like genes). isolates from poland harbored several bla(cmy) genes (bla(cmy-4), bla(cmy-12), bla(cmy-14), bla(cmy-15), and bla(cmy-38) and the new gene bla(cmy-45)), while isolates from italy and greece harbored bla(cmy-16) only. earlier isolates with bla(cmy-4) or bla(cmy-12), recovered in ... | 2011 | 21402851 |
| in vitro activity of ceftaroline against gram-positive and gram-negative pathogens isolated from patients in canadian hospitals in 2009. | the in vitro activities of ceftaroline and comparative agents were determined for a collection of the most frequently isolated bacterial pathogens from hospital-associated patients across canada in 2009 as part of the ongoing canward surveillance study. in total, 4,546 isolates from 15 sentinel canadian hospital laboratories were tested using the clinical and laboratory standards institute (clsi) broth microdilution method. compared with other cephalosporins, including ceftobiprole, cefepime, an ... | 2011 | 21402844 |
| new variant salmonella genomic island 1-u in proteus mirabilis clinical and food isolates from south china. | 2011 | 21393148 | |
| cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. | some natural products consisting of the alkaloids yohimbine and vincamine (indole-type), scopolamine and atropine (tropane-type), colchicine (tropolone-type), allantoin (imidazolidine-type), trigonelline (pyridine-type) as well as octopamine, synephrine, and capsaicin (exocyclic amine-type); the flavonoid derivatives quercetin, apigenin, genistein, naringin, silymarin, and silibinin; and the phenolic acids namely gallic acid, caffeic acid, chlorogenic acid, and quinic acid, were tested for their ... | 2011 | 21391841 |
| in vitro synthesis of biogenic amines by brochothrix thermosphacta isolates from meat and meat products and the influence of other microorganisms. | twenty brochothrix thermosphacta strains tested for biogenic amines (bas) production, formed histamine (6.6-16.2 mg/kg) and tyramine (18.7-35.4 mg/kg) but neither putrescine nor cadaverine. six of the twenty strains were also investigated in respect of their influence on the synthesis of bas by escherichia coli, pseudomonas sp., proteus mirabilis and lactobacillus sakei. in pure culture escherichia coli produced all of the studied amines (histamine, tyramine, putrescine and cadaverine) with a to ... | 2011 | 21382674 |
| relationship between the camp levels in leukocytes and the cytokine balance in patients surviving gram negative bacterial pneumonia. | lipopolysaccharide-stimulated leukocytes secrete proinflammatory cytokines including tumor necrosis factor-a and interleukin-12. over-activation of host defense systems may result in severe tissue damage and requires regulation. granulocyte colony-stimulating factor and interleukin-10 are candidate cytokines for inducing tolerance to lipopolysaccharide re-stimulation. we compared cytokines secreted by lipopolysaccharide-stimulated blood cells from patients who had survived gram negative bacteria ... | 2011 | 21373266 |
| chemical composition and antimicrobial activity of the essential oil of the leaves of feronia elephantum (rutaceae) from north west karnataka. | the essential oil of the leaves of feronia elephantum corr. was analyzed by gas chromatography and gas chromatography/mass spectrometry. the main constituents were beta-pinene (28.4%), z-anethole (22.1%), methyl chavicol (12.0%) and e-anethole (8.1%), among thirty-three identified compounds, which represented 92.6% of the total oil. the antimicrobial activity was tested against five gram-positive and eight gram-negative bacteria, and four fungi. the oil was active against micrococcus luteus (gra ... | 2011 | 21366066 |
| confirmation of hiv-like sequences in respiratory tract bacteria of cambodian and kenyan hiv-positive pediatric patients. | bacteria and yeasts isolated from respiratory tracts of 39 cambodian and 28 kenyan hiv-positive children were tested for the presence of hiv-1 sequences. | 2011 | 21358602 |
| in vitro activity of ceftobiprole against frequently encountered aerobic and facultative gram-positive and gram-negative bacterial pathogens: results of the canward 2007-2009 study. | the in vitro activity of ceftobiprole was evaluated against 15 011 clinical isolates obtained from patients in canadian hospitals between 2007 and 2009. all staphylococcus aureus were susceptible to ceftobiprole (mic(90)'s for methicillin-susceptible staphylococcus aureus and methicillin-resistant staphylococcus aureus of = 1 µg/ml and 2 µg/ml, respectively). ceftobiprole was active against penicillin-susceptible streptococcus pneumoniae (mic(90), = 0.06 µg/ml), penicillin-resistant streptococcu ... | 2011 | 21353964 |
| broad-spectrum antimicrobial efficacy of peptide a3-apo in mouse models of multidrug-resistant wound and lung infections cannot be explained by in vitro activity against the pathogens involved. | although the designer proline-rich antimicrobial peptide a3-apo has only modest activity against escherichia coli and acinetobacter baumannii in vitro, in mouse models of systemic and wound infections it shows superior efficacy compared with conventional antibiotics. in this study, the efficacy of a3-apo in several additional mouse models was investigated, including staphylococcus aureus wound infection, mixed klebsiella pneumoniae-a. baumannii-proteus mirabilis wound infection and k. pneumoniae ... | 2011 | 21353493 |
| bacteremia in a multilevel geriatric hospital. | bloodstream infection (bsi) is a major cause of morbidity and mortality in hospitals. bacteremia in the elderly remains a diagnostic as well as a therapeutic challenge to the clinician. | 2010 | 21333922 |
| [one-stage revision of knee endoprosthesis due to periprosthetic infection and klippel-trenaunay syndrome]. | we present the case of a patient with klippel-trenaunay syndrome (kts) who underwent a one-stage revision of an infected total knee arthroplasty. a detailed orthopedic description of kt is presented as well as a discussion on the implementation of one-stage or multi-stage revision following infections of total knee arthroplasty. due to vascular anomalies with severe coagulation problems, soft tissue swelling and increased risk of infection, surgical treatment of such patients presents a special ... | 2011 | 21327613 |
| thrombocytes are effectors of the innate immune system releasing human beta defensin-3. | thrombocyte concentrate i.e. platelet-rich plasma (prp) has become a popular adjunct for many surgical procedures. it is believed to improve bone and soft tissue healing. recently antimicrobial effects of the autologous preparation were reported by several groups. in this study we investigated the antimicrobial effect of prp against gram-negative microbes which frequently cause severe complications in orthopaedic trauma surgery. | 2011 | 21310405 |
| microbial burden of some herbal antimalarials marketed at elele, rivers state. | herbal antimalarials still remain an alternative to our traditional communities who can not afford orthodox antimalarials. this study was aimed at investigating the microbial quality of six herbal antimalarials using standard microbiological methods. of the six preparations analyzed, "schnapps", palm wine and water were the media of preparation; the water base preparations recorded higher microbial load. the mean microbial load was 159.5 × 10(5) cfu/ml and 217.4 × 10(2)cfu/ml in water and alcoho ... | 2009 | 21304626 |
| antibacterial activity of the indigenous earthworms lampito mauritii (kinberg) and perionyx excavatus (perrier). | earthworms respond to microbial infection through cellular and humoral defense mechanisms such as antimicrobial protein secretions. most of the humoral defense proteins are synthesized in the skin itself. | 2011 | 21299431 |
| expression and characterization of a second l-amino acid deaminase isolated from proteus mirabilis in escherichia coli. | l-amino acid deaminases catalyze the deamination of natural l-amino acids. two types of l-amino acid deaminase have been identified in proteus species. one exhibits high levels of activity toward a wide range of aliphatic and aromatic l-amino acids, typically l-phenylalanine, whereas the other acts on a relatively narrow range of basic l-amino acids, typically l-histidine. in this study, we cloned, expressed, and characterized a second amino acid deaminase, termed pm1, from p. mirabilis kctc 256 ... | 2011 | 21298676 |
| prevalence and phenotypic characterisation of carbapenem resistance in enterobacteriaceae bloodstream isolates in a tertiary care hospital in india. | 2011 | 21295949 | |
| urease | urease is produced by numerous taxonomically diverse bacterial species, including normal flora and nonpathogens. also, urease has been demonstrated as a potent virulence factor for some species, including proteus mirabilis (51), staphylococcus saprophyticus (36), and helicobacter pylori (23). urease is central to h. pylori metabolism and virulence, is necessary for its colonization of the gastric mucosa, and is a potent immunogen that elicits a vigorous immune response. this enzyme is used for t ... | 2001 | 21290719 |
| chromosome-encoded ampc and ctx-m extended-spectrum ß-lactamases in clinical isolates of proteus mirabilis from korea. | among 222 proteus mirabilis clinical isolates collected from 17 hospitals in korea in 2008, 28 (12.6%) and 8 (3.6%) isolates exhibited extended-spectrum ß-lactamase (esbl) and ampc phenotypes, respectively. the most common type of esbl gene identified by pcr and sequencing experiments was bla(ctx-m-14a) (n = 12). the bla(ctx-m-90) (n = 4), bla(ctx-m-15) (n = 3), bla(ctx-m-12) (n = 3), bla(ctx-m-2) (n = 2), bla(ctx-m-14b) (n = 1), bla(tem-52) (n = 5), and bla(shv-12) (n = 1) genes were also detec ... | 2011 | 21282448 |
| influence of referral bias on the clinical characteristics of patients with gram-negative bloodstream infection. | summaryreferral bias can influence the results of studies performed at tertiary-care centres. in this study, we evaluated demographic and microbiological factors that influenced referral of patients with gram-negative bloodstream infection (bsi). we identified 2919 and 846 unique patients with gram-negative bsi in a referral cohort of patients treated at mayo clinic hospitals and a population-based cohort of olmsted county, minnesota, residents between 1 january 1998 and 31 december 2007, respec ... | 2011 | 21281552 |
| assessment of effectiveness and safety of ibicella lutea extract in the control of experimental proteus mirabilis urinary tract infection. | proteus mirabilis is an important cause of complicated urinary tract infections (uti). like many other microorganisms, p. mirabilis has acquired resistance to many antibiotics. due to the serious effects associated with uropathogenic p. mirabilis and the problems related to the use of antibiotics, alternative strategies for its control must be developed. previously, we studied the effect of ibicella lutea extract, a south american indigenous plant, on in vitro uropathogenicity of p. mirabilis. w ... | 2010 | 21252462 |
| plasmid-mediated quinolone resistance in expanded spectrum beta lactamase producing enterobacteriaceae in morocco. | although independently acquired, plasmid-mediated quinolone resistance appears to be linked with extended-spectrum or ampc-type beta-lactamases. since no data are available in african countries, the prevalence of qnr genes at the university hospital ibn rochd, casablanca, morocco, was investigated. | 2010 | 21252459 |
| treatment of endocarditis due to proteus species: a literature review. | endocarditis due to proteus species is very rare. we report a case of endocarditis due to proteus mirabilis that was successfully treated with ampicillin and gentamicin, and review the treatment regimens of previously published cases of proteus endocarditis. | 2011 | 21237686 |
| carijodienone from the octocoral carijoa multiflora. a spiropregnane-based steroid. | two new steroids (1 and 2) and the known pregna-1,4,20-trien-3-one (3) have been isolated from the pacific octocoral carijoa multiflora. compound 1 possesses a novel spiropregnane-based steroidal skeleton. the photochemical transformation of 3 into 1 allowed the assignment of the absolute configuration at c-10 of 1. the antibacterial activities of compounds 1 and 3 were evaluated against a panel of bacterial strains. | 2011 | 21235217 |
| the prevalence and bacteriology of asymptomatic bacteriuria among antenatal patients in nnamdi azikiwe university teaching hospital nnewi; south eastern nigeria. | background: urinary tract infection in pregnancy leads to poor pregnancy outcome. diagnosis and treatment of asymptomatic bacteriuria markedly improves pregnancy outcome as well as reduce the incidence of acute pyelonephritis. objective: to determine the prevalence and bacteriology of asymptomatic bacteriuria among antenatal patients in our centre, and to know if routine screening will be justifiable. materials and methods: this was a prospective study carried out between april and august 2008. ... | 2010 | 21220855 |
| evaluation of antibacterial activity of belizean plants: an improved method. | the influences of medium type, inoculum density, and a cold incubation on antimicrobial assay sensitivity were tested. the largest and most distinct zones were produced using nutrient agar and the 1/10 4 inoculum density for staphylococcus aureus and proteus mirabilis but a 1/10 12 inoculum density for pseudomonas aeruginosa and escherichia coli . the greatest number of zones were detected without cold incubation. using this method, eight plants from belize were screened for antibacterial activi ... | 2000 | 21214435 |
| screening of bloodborne pathogens and antimicrobial susceptibility testing among cancer patients. | to screen bloodborne pathogens and test for antimicrobial susceptibility among patients with different types of cancer. | 2010 | 21198306 |
| pan-susceptible proteus mirabilis septicemia in a patient multicolonized by pan-resistant bacteria. | 2010 | 21193275 | |
| the salmonella genomic island 1 is specifically mobilized in trans by the inca/c multidrug resistance plasmid family. | the salmonella genomic island 1 (sgi1) is a salmonella enterica-derived integrative mobilizable element (ime) containing various complex multiple resistance integrons identified in several s. enterica serovars and in proteus mirabilis. previous studies have shown that sgi1 transfers horizontally by in trans mobilization in the presence of the inca/c conjugative helper plasmid pr55. | 2010 | 21187963 |
| synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. | a facile and one-pot synthesis of a series of novel spiropyrrolidines/pyrrolizidines with β-lactam substituent has been accomplished through 1,3-dipolar cycloaddition reaction of alkenyl esters derived from β-lactam aldehyde as dipolarophile with the dipole azomethine ylide derived from 1,2- and 1,3-diketones and secondary amino acids. the synthesized compounds were evaluated for antimicrobial activities and found to exhibit relatively good antibacterial activity at lower concentration against f ... | 2010 | 21177001 |
| the nationwide study of bacterial pathogens associated with urinary tract infections conducted by the japanese society of chemotherapy. | this study was conducted by the japanese society of chemotherapy and is the first nationwide study on bacterial pathogens isolated from patients with urinary tract infections at 28 hospitals throughout japan between january 2008 and june 2008. a total of 688 bacterial strains were isolated from adult patients with urinary tract infections. the strains investigated in this study are as follows: enterococcus faecalis (n = 140), escherichia coli (n = 255), klebsiella pneumoniae (n = 93), proteus mi ... | 2010 | 21174142 |
| unexpected coregulator range for the global regulator lrp of escherichia coli and proteus mirabilis. | the lrp/asnc family of transcription factors links gene regulation to metabolism in bacteria and archaea. members of this family, collectively, respond to a wide range of amino acids as coregulators. in escherichia coli, lrp regulates over 200 genes directly and is well known to respond to leucine and, to a somewhat lesser extent, alanine. we focused on lrp from proteus mirabilis and e. coli, orthologs with 98% identity overall and identical helix-turn-helix motifs, for which a previous study ne ... | 2010 | 21169483 |
| [comparison of four phenotypic methods to detect extended-spectrum betalactamases]. | to compare the efficacy of four phenotypic methods for the identification of strains producing extended-spectrum β-lactamases isolated from urine cultures. | 2010 | 21152726 |
| photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections. | fullerenes are under intensive study for potential biomedical applications. we have previously reported that a c60 fullerene functionalized with three dimethylpyrrolidinium groups (bf6) is a highly active broad-spectrum antimicrobial photosensitizer in vitro when combined with white-light illumination. we asked whether this high degree of in vitro activity would translate into an in vivo therapeutic effect in two potentially lethal mouse models of infected wounds. | 2010 | 21143031 |
| necrotising otitis externa: an unusual cause of cranial nerve palsy in a diabetic haemodialysis patient. | we present an unusual case of necrotising otitis externa (noe) causing a lower motor neurone facial nerve palsy in a patient with diabetes mellitus and receiving maintenance haemodialysis for end-stage renal disease (esrd). pseudomonas aeruginosa is the most common pathogen isolated in noe, although our case involved the non-typical pathogens aspergillus flavus and proteus mirabilis. we discuss the need for diagnostic rigour and the importance of considering atypical infective pathology in patie ... | 2010 | 21125035 |
| clinical aspects and genetic analysis of taiwanese patients with the phenotype of hyper-immunoglobulin e recurrent infection syndromes (hies). | hyper-immunoglobulin e recurrent infection syndromes (hies) has characteristic features and identified mutations. this study investigated clinical features and causal candidate mutations in taiwanese patients with the hies phenotype on referral base over 23 million inhabitants. | 2010 | 21120687 |
| ceftaroline activity against pathogens associated with complicated skin and skin structure infections: results from an international surveillance study. | to assess the spectrum and potency of ceftaroline, a novel anti-methicillin-resistant staphylococcal cephalosporin, against a 2008 surveillance collection of clinical isolates from patients in the usa and europe. | 2010 | 21115451 |
| [occurrence of 16s rrna methylase arma producing enterobacteriaceae in a general hospital in warsaw, poland]. | resistance to gentamicin, amikacin and kanamycin was screened in 270 clinical isolates of enterobacteriaceae originated from april 19 to may 19, 2010 in a regular hospital in warsaw, poland. most of the isolated bacteria were considered pathogenic. nineteen isolates (7%) were simultaneously resistant to two or three of the tested aminoglycosides. mics of the three aminoglycosides ranged form 128 to 1024 mcg/ml for six isolates. these isolates were suspected to produce 16s rrna methylase. genes e ... | 2010 | 21114012 |
| [epidemiological and bacteriological characteristics of uropathogen bacteria isolated in a pediatric environment]. | urinary tract infection (uti) in children is a grave pathology, which requires a fast and effective care. bacteriological and epidemiological data play a determining role in patient's care. we report a retrospective study, which spreads out from january 1st till august 31st, 2009, having concerned hospitalized children for urinary infection in pediatrics service of farhat hached teaching hospital in sousse. our series contained 51 children with a sex ratio of 0.76, an average age of 32 months. t ... | 2010 | 21111582 |
| [a modified rat model for infection-induced stone formation]. | to employ a newly modified rat model for infection-induced bladder stone formation. | 2010 | 21092517 |
| salmonella genomic islands and antibiotic resistance in salmonella enterica. | antibiotic resistance in several salmonella enterica serovars that cause gastrointestinal disease in humans is due to a set of related genomic islands carrying a class 1 integron, which carries the resistance genes. salmonella genomic island 1 (sgi1), the first island of this type, was found in s. enterica serovar typhimurium dt104 isolates, which are resistant to ampicillin, chloramphenicol, florfenicol, streptomycin, spectinomycin, sulfonamides and tetracycline. several salmonella serovars and ... | 2010 | 21073312 |
| 16s rdna sequence analysis of culturable marine biofilm forming bacteria from a ship's hull. | marine bacteria from the hull of a ship in the form of biofilms or microfouling were isolated, cultured, and identified by phylogenetic analysis using 16s rdna sequences. with an average length of 946 bp, all the 16 sequences were classified using the ribosomal database project (rdp) and were submitted to the national center for biotechnology information. phylogenetic analysis using 16s rdna sequences indicated that the 16 strains belonged to the firmicutes (ik-mb6 exiguobacterium aurantiacum, i ... | 2010 | 21038149 |
| emergence of klebsiella pneumoniae carbapenemase-producing proteus mirabilis in hangzhou, china. | carbapenems are used to treat severe infections caused by multi-drug-resistant organisms, however, the emergence of carbapenem-resistant bacterial isolates is becoming an increasing therapeutic challenge. since the first klebsiella (k.) pneumoniae carbapenemase (kpc)-producing k. pneumoniae was reported in 2001, kpc-producing isolates have been found increasingly, specially in enterobacteriaceae. the aim of this study was to characterize the mechanisms of a carbapenem-resistant proteus (p.) mira ... | 2010 | 21034629 |
| occurrence of gram-negative bacteria in hens' eggs depending on their source and storage conditions. | the aim of this study was to analyse the qualitative composition of gram-negative microbes, mainly of the family enterobacteriaceae, including pathogenic bacteria such as salmonella, in the albumens and yolks and on the shells of hens' eggs, depending on their source and on the temperature and duration of their storage. a total of 375 table eggs were studied, from a large-scale poultry farm, a small-scale poultry farm and a supermarket. each group was divided into 5 subgroups according to the te ... | 2010 | 21033566 |
| incidence of postoperative eye infections in a private eye hospital in lagos, nigeria. | there is a dearth of information on postoperative eye infections in nigeria and most hospitals do not have an infection control program in place. | 2010 | 21033323 |
| antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. | the chemical composition and antibacterial activity of essential oils from 10 commonly consumed herbs: citrus aurantium, c. limon, lavandula angustifolia, matricaria chamomilla, mentha piperita, m. spicata, ocimum basilicum, origanum vulgare, thymus vulgaris and salvia officinalis have been determined. the antibacterial activity of these oils and their main components; i.e. camphor, carvacrol, 1,8-cineole, linalool, linalyl acetate, limonene, menthol, a-pinene, b-pinene, and thymol were assayed ... | 2010 | 21030907 |
| implication of proteus mirabilis in an outbreak of gastroenteritis. | 1946 | 21027291 | |
| [the incidence of extended spectrum beta-lactamases in proteus mirabilis strains isolated in 2007-2009]. | proteus sp. rods are opportunistic human pathogens, isolated mainly from urinary tract infections. they are naturally susceptible to most antimicrobials. however, acquisition of genes for extended spectrum beta-lactamases on plasmids and irrational antimicrobial treatment increase amount of multidrug resistant strains and lead to their selection. the aim of this study was to evaluate production of esbls by double disc synergy test and antimicrobial susceptibility of p mirabilis strains by disc d ... | 2010 | 20976952 |
| survival of phosphate-solubilizing bacteria against dna damaging agents. | phosphate-solubilizing bacteria (psbs) were isolated from different plant rhizosphere soils of various agroecological regions of india. these isolates showed synthesis of pyrroloquinoline quinone (pqq), production of gluconic acid, and release of phosphorus from insoluble tricalcium phosphate. the bacterial isolates synthesizing pqq also showed higher tolerance to ultraviolet c radiation and mitomycin c as compared to escherichia coli but were less tolerant than deinococcus radiodurans. unlike e ... | 2010 | 20962905 |
| three enzymatic steps required for the galactosamine incorporation into core lipopolysaccharide. | the core lipopolysaccharides (lps) of proteus mirabilis as well as those of klebsiella pneumoniae and serratia marcescens are characterized by the presence of a hexosamine-galacturonic acid disaccharide (αhexn-(1,4)-αgala) attached by an α1,3 linkage to l-glycero-d-manno-heptopyranose ii (l-glycero-α-d-manno-heptosepyranose ii). in k. pneumoniae, s. marcescens, and some p. mirabilis strains, hexn is d-glucosamine, whereas in other p. mirabilis strains, it corresponds to d-galactosamine. previous ... | 2010 | 20959463 |
| antimicrobial susceptibility of intra-abdominal gram-negative bacilli from europe: smart europe 2008. | as part of the worldwide study for monitoring antimicrobial resistance trends (smart), a total of 3,030 clinical isolates of gram-negative bacilli from intra-abdominal infections were collected from 43 hospital centres from 13 european countries during 2008. of 51 species, the most commonly isolated species were escherichia coli (49.3%), followed by klebsiella pneumoniae (10.5%) and pseudomonas aeruginosa (8.6%). respectively, 17.9%, 11.6%, 5.5% and 4.5% of k. pneumoniae, e. coli, proteus mirabi ... | 2010 | 20953653 |
| [the bacteriological profile of bacteriuria in residents of a long-term geriatric facility]. | little is known on the bacteriological profile of consecutive urine samples in elderly patients institutionalized in nursing homes. | 2010 | 20941920 |
| synergy of nitric oxide and silver sulfadiazine against gram-negative, gram-positive, and antibiotic-resistant pathogens. | the synergistic activity between nitric oxide (no) released from diazeniumdiolate-modified proline (proli/no) and silver(i) sulfadiazine (agsd) was evaluated against escherichia coli, enterococcus faecalis, proteus mirabilis, pseudomonas aeruginosa, staphylococcus aureus and staphylococcus epidermidis using a modified broth microdilution technique and a checkerboard-type assay. the combination of no and agsd was defined as synergistic when the fractional bactericidal concentration (fbc) was calc ... | 2010 | 20939612 |
| a mutational analysis and molecular dynamics simulation of quinolone resistance proteins qnra1 and qnrc from proteus mirabilis. | the first report on the transferable, plasmid-mediated quinolone-resistance determinant qnra1 was in 1998. since then, qnr alleles have been discovered worldwide in clinical strains of gram-negative bacilli. qnr proteins confer quinolone resistance, and belong to the pentapeptide repeat protein (prp) family. several prp crystal structures have been solved, but little is known about the functional significance of their structural arrangement. | 2010 | 20932305 |
| extended-spectrum β-lactamases in gram negative bacteria. | extended-spectrum β-lactamases (esbls) are a group of plasmid-mediated, diverse, complex and rapidly evolving enzymes that are posing a major therapeutic challenge today in the treatment of hospitalized and community-based patients. infections due to esbl producers range from uncomplicated urinary tract infections to life-threatening sepsis. derived from the older tem is derived from temoniera, a patient from whom the strain was first isolated in greece. β-lactamases, these enzymes share the abi ... | 2010 | 20927289 |
| proteobactin and a yersiniabactin-related siderophore mediate iron acquisition in proteus mirabilis. | proteus mirabilis causes complicated urinary tract infections (utis). while the urinary tract is an iron-limiting environment, iron acquisition remains poorly characterized for this uropathogen. microarray analysis of p. mirabilis hi4320 cultured under iron limitation identified 45 significantly upregulated genes (p ≤ 0.05) that represent 21 putative iron-regulated systems. two gene clusters, pmi0229-0239 and pmi2596-2605, encode putative siderophore systems. pmi0229-0239 encodes a non-ribosomal ... | 2010 | 20923418 |
| [etiology and sensitivity of uropathogens identified in uncomplicated lower urinary tract infections in women (aresc study): implications on empiric therapy]. | to determine the etiology and susceptibility of uropathogens identified in women with uncomplicated lower urinary tract infections (uti). | 2011 | 20889171 |
| clinical and molecular epidemiology of extended-spectrum β-lactamase-producing escherichia coli and klebsiella pneumoniae in a long-term study from japan. | the detection rates of extended-spectrum β-lactamase (esbl)-producing bacteria in japan are very low (∼5%) compared with those obtained worldwide. further, the current trend of these bacteria in japan is not known, and few studies with longitudinal observations have been reported. to obtain epidemiologic data on esbl-producing bacteria, their genotypic features, and their antibiotic resistance patterns in japan, we analyzed bacterial isolates from hospitalized patients at our institution over th ... | 2011 | 20859753 |
| prevalence of bacteria and parasites in white ibis in egypt. | a field survey was conducted to evaluate the prevalence of bacterial infections among free-living white ibis (nipponia nippon) in which 92 bacterial isolates were recovered from 193 different internal organs of 55 apparently healthy ibis. escherichia coli and salmonella spp. were isolated at rates of 43.6% and 14.5%, respectively. the other bacterial pathogens isolated were shigella spp. (34.5%), enterobacter spp. (21.8%) citrobacter spp. (18.1%), klebsiella pneumonia (16.3), staphylococcus aure ... | 2010 | 20857378 |
| prevalence and resistance patterns of extended-spectrum and ampc β-lactamase in escherichia coli, klebsiella pneumoniae, proteus mirabilis, and salmonella serovar stanley in a korean tertiary hospital. | a total of 100 clinical isolates of escherichia coli (n = 35), klebsiella pneumoniae (n = 63), proteus mirabilis (n = 1), and salmonella serovar stanley (n = 1), showing resistance to cefoxitin, or returning positive in extended-spectrum β-lactamase (esbl) by clinical and laboratory standards institute (clsi) esbl confirmatory method, were studied. the isolates were examined by the boronic acid (ba) disk test, polymerase chain reaction, and pulsed-field gel electrophoresis (pfge) to investigate ... | 2010 | 20854475 |
| risk factors for hospital-acquired urinary tract infection: a case-control study. | the objective is to assess risk factors and microbiological aspects of hospital-acquired urinary tract infection (hauti) on six wards of a general regional hospital in serbia. a case-control study was nested within prospective cohort hautis study conducted from january 1 to december 31, 2007. three controls were identified for each patient with hauti, being chronologically the next three patients surveyed who did not develop hauti. the patients and controls were matched by sex and age (±5 years) ... | 2011 | 20848199 |
| high frequency of beta-lactam susceptibility in ctx-m-type extended-spectrum-beta-lactamase-producing klebsiella pneumoniae, escherichia coli and proteus mirabilis according to the new clsi recommendations. | 2010 | 20846935 | |
| antibiotic susceptibility pattern in urinary isolates of gram negative bacilli with special reference to ampc β-lactamase in a tertiary care hospital. | resistance to higher antimicrobial agent is commonly seen in gram negative bacilli. this issue is a challenging problem to the medical practitioners in addition to it is financial impact on the health care system. | 2010 | 20842250 |
| the in vitro antimicrobial activity of fruit and leaf crude extracts of momordica charantia: a tanzania medicinal plant. | to evaluate the antimicrobial activity of momordica charantia extracts on reference strains and microorganisms isolated from clinical specimens. | 2009 | 20842240 |