Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| maldi-tof mass spectrometry: a powerful tool for clinical microbiology at hôpital principal de dakar, senegal (west africa). | our team in europe has developed the routine clinical laboratory identification of microorganisms by matrix-assisted laser desorption ionization time-of-flight (maldi-tof) mass spectrometry (ms). to evaluate the utility of maldi-tof ms in tropical africa in collaboration with local teams, we installed an apparatus in the hôpital principal de dakar (senegal), performed routine identification of isolates, and confirmed or completed their identification in france. in the case of discordance or a la ... | 2015 | 26716681 |
| safe and effective deodorization of malodorous fungating tumors using topical metronidazole 0.75 % gel (gk567): a multicenter, open-label, phase iii study (rdt.07.sre.27013). | malignant fungating tumors are neoplastic tumors associated with skin ulcers, which are susceptible to microbial colonization. bacterial infection and proliferation may lead to malodor causing distress to patients. metronidazole-an effective agent against anaerobes-may contribute to deodorization and improvement in quality of life (qol). this study investigated the efficacy and safety of topical metronidazole 0.75 % gel for alleviation of malodor in anaerobically infected fungating neoplastic tu ... | 2015 | 26715293 |
| safe and effective deodorization of malodorous fungating tumors using topical metronidazole 0.75 % gel (gk567): a multicenter, open-label, phase iii study (rdt.07.sre.27013). | malignant fungating tumors are neoplastic tumors associated with skin ulcers, which are susceptible to microbial colonization. bacterial infection and proliferation may lead to malodor causing distress to patients. metronidazole-an effective agent against anaerobes-may contribute to deodorization and improvement in quality of life (qol). this study investigated the efficacy and safety of topical metronidazole 0.75 % gel for alleviation of malodor in anaerobically infected fungating neoplastic tu ... | 2015 | 26715293 |
| antibacterial activities of the methanol extracts and compounds from erythrina sigmoidea against gram-negative multi-drug resistant phenotypes. | in the present study, the methanol extracts from the leaves, as well as compounds namely sigmoidin i (1), atalantoflavone (2), bidwillon a (3), neocyclomorusin (4), 6α-hydroxyphaseollidin (5) and neobavaisoflavone (6) (from the bark extract) were tested for their activities against a panel of gram-negative bacteria including multi-drug resistant (mdr) phenotypes. | 2015 | 26715029 |
| circlator: automated circularization of genome assemblies using long sequencing reads. | the assembly of dna sequence data is undergoing a renaissance thanks to emerging technologies capable of producing reads tens of kilobases long. assembling complete bacterial and small eukaryotic genomes is now possible, but the final step of circularizing sequences remains unsolved. here we present circlator, the first tool to automate assembly circularization and produce accurate linear representations of circular sequences. using pacific biosciences and oxford nanopore data, circlator correct ... | 2015 | 26714481 |
| pseudomonas aeruginosa induced airway epithelial injury drives fibroblast activation: a mechanism in chronic lung allograft dysfunction. | bacterial infections after lung transplantation cause airway epithelial injury and are associated with an increased risk of developing bronchiolitis obliterans syndrome. the damaged epithelium is a source of alarmins that activate the innate immune system, yet their ability to activate fibroblasts in the development of bronchiolitis obliterans syndrome has not been evaluated. two epithelial alarmins were measured longitudinally in bronchoalveolar lavages from lung transplant recipients who devel ... | 2016 | 26714197 |
| escherichia coli population structure and antibiotic resistance at a buffalo/cattle interface in southern africa. | at a human/livestock/wildlife interface, escherichia coli populations were used to assess the risk of bacterial and antibiotic resistance dissemination between hosts. we used phenotypic and genotypic characterization techniques to describe the structure and the level of antibiotic resistance of e. coli commensal populations and the resistant enterobacteriaceae carriage of sympatric african buffalo (syncerus caffer caffer) and cattle populations characterized by their contact patterns in the sout ... | 2016 | 26712551 |
| comparison of 2 chromogenic media for the detection of extended-spectrum β-lactamase producing enterobacteriaceae stool carriage in nursing home residents. | chromid esbl agar and brilliance esbl agar were compared for the isolation of extended-spectrum β-lactamase (esbl)-producing enterobacteriaceae from 298 stools. these had comparable sensitivity and selectivity for the 116 positive samples. pre-enrichment with cefpodoxime and extending incubation to 48 hours after direct plating both significantly increased sensitivity but reduced selectivity of both agars. | 2016 | 26712266 |
| efficacy and safety of afn-1252, the first staphylococcus-specific antibacterial agent, in the treatment of acute bacterial skin and skin structure infections, including those in patients with significant comorbidities. | this open-label noncontrolled, phase ii multicenter trial was designed to evaluate the safety, tolerability, and efficacy of 200 mg of afn-1252, a selective inhibitor of staphylococcus aureus enoyl-acyl carrier protein reductase (fabi), given by mouth twice daily in the treatment of acute bacterial skin and skin structure infections (absssi) due to staphylococci. important aspects of the current study included a comparison of early response efficacy endpoints with end-of-treatment and follow-up ... | 2016 | 26711777 |
| kpc-like carbapenemase-producing enterobacteriaceae colonizing patients in europe and israel. | in a 2008-2011 survey, 17,945 patients in 18 hospital units in europe and israel were screened for carriage of klebsiella pneumoniae carbapenemase (kpc)-producing enterobacteriaceae, resulting in identification of 124 positive patients. the isolates were dominated by klebsiella pneumoniae sequence type 258 (st258) kpc-2 and st512 kpc-3, mainly from greece and italy, respectively, whereas israeli isolates were of diverse species, clones, and kpc variants. various blakpc platforms were observed, a ... | 2016 | 26711772 |
| suppression of emergence of resistance in pathogenic bacteria: keeping our powder dry, part 2. | we are in a crisis of bacterial resistance. for economic reasons, most pharmaceutical companies are abandoning antimicrobial discovery efforts, while, in health care itself, infection control and antibiotic stewardship programs have generally failed to prevent the spread of drug-resistant bacteria. at this point, what can be done? the first step has been taken. governments and international bodies have declared there is a worldwide crisis in antibiotic drug resistance. as discovery efforts begin ... | 2016 | 26711766 |
| what is the appropriate meropenem mic for screening of carbapenemase-producing enterobacteriaceae in low-prevalence settings? | infection with carbapenemase-producing enterobacteriaceae (cpe) has been shown to cause significant illness among hospitalized patients. given the paucity of treatment options, there is a critical need to stop the spread of cpe. however, screening for the presence of cpe in laboratory settings has been challenging. in order to assess the effectiveness of current cpe detection guidelines, we analyzed the meropenem mic distribution for a large set of clinical enterobacteriaceae isolates. a total o ... | 2016 | 26711746 |
| direct identification and antimicrobial susceptibility testing of bacteria from positive blood culture bottles by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and the vitek 2 system. | we evaluated the reliability and accuracy of the combined use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) bacterial identification and vitek 2 antimicrobial susceptibility testing (ast) for bacteria from positive blood culture bottles. | 2015 | 26709258 |
| direct identification and antimicrobial susceptibility testing of bacteria from positive blood culture bottles by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and the vitek 2 system. | we evaluated the reliability and accuracy of the combined use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) bacterial identification and vitek 2 antimicrobial susceptibility testing (ast) for bacteria from positive blood culture bottles. | 2015 | 26709258 |
| [preliminary analyses on bacterial diversity and resistance in infection-related skin disorders]. | to explore the bacterial diversity and resistance in infection-related skin disorders. | 2015 | 26704163 |
| identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities. | treating bacterial infections can be difficult due to innate or acquired resistance mechanisms, and the formation of biofilms. cyclic lipopeptides derived from fusaricidin/li-f natural products represent particularly attractive candidates for the development of new antibacterial and antibiofilm agents, with the potential to meet the challenge of bacterial resistance to antibiotics. a positional-scanning combinatorial approach was used to identify the amino acid residues responsible for driving a ... | 2015 | 26703794 |
| identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities. | treating bacterial infections can be difficult due to innate or acquired resistance mechanisms, and the formation of biofilms. cyclic lipopeptides derived from fusaricidin/li-f natural products represent particularly attractive candidates for the development of new antibacterial and antibiofilm agents, with the potential to meet the challenge of bacterial resistance to antibiotics. a positional-scanning combinatorial approach was used to identify the amino acid residues responsible for driving a ... | 2015 | 26703794 |
| prevalence and antimicrobial resistance of microbes causing bloodstream infections in unguja, zanzibar. | bloodstream infections (bsi) are frequent and cause high case-fatality rates. urgent antibiotic treatment can save patients' lives, but antibiotic resistance can render antibiotic therapy futile. this study is the first to collect epidemiological data on bsi from unguja, zanzibar. | 2015 | 26700032 |
| utility of whole-genome sequencing in characterizing acinetobacter epidemiology and analyzing hospital outbreaks. | acinetobacter baumannii frequently causes nosocomial infections and outbreaks. whole-genome sequencing (wgs) is a promising technique for strain typing and outbreak investigations. we compared the performance of conventional methods with wgs for strain typing clinical acinetobacter isolates and analyzing a carbapenem-resistant a. baumannii (crab) outbreak. we performed two band-based typing techniques (pulsed-field gel electrophoresis and repetitive extragenic palindromic-pcr), multilocus sequen ... | 2016 | 26699703 |
| rapid and sensitive detection of shigella spp. and salmonella spp. by multiple endonuclease restriction real-time loop-mediated isothermal amplification technique. | shigella and salmonella are frequently isolated from various food samples and can cause human gastroenteritis. here, a novel multiple endonuclease restriction real-time loop-mediated isothermal amplification technology (mert-lamp) were successfully established and validated for simultaneous detection of shigella strains and salmonella strains in only a single reaction. two sets of mert-lamp primers for 2 kinds of pathogens were designed from ipah gene of shigella spp. and inva gene of salmonella ... | 2015 | 26697000 |
| an unusual case of hepatosplenic αβ t-cell lymphoma presenting with coombs'-negative hemolytic anemia. | hepatosplenic t-cell lymphoma (hstcl) is a rare and aggressive extranodal t-cell lymphoma that comprises <5% of peripheral t-cell lymphomas. the majority of cases harbor the γδ t-cell receptor (tcr), but recently, a few cases have been shown to express the αβ tcr. comparison of these two subtypes (αβ and γδ) shows similar clinicopathologic and cytogenetic features; however, due to the paucity of reported cases, it is not clear whether they are prognostically distinct entities. we report a case o ... | 2015 | 26688667 |
| molecular characterization of midgut microbiota of aedes albopictus and aedes aegypti from arunachal pradesh, india. | microbiota inhabiting midguts of mosquitoes play a key role in the host - parasite interaction and enhance vectorial capacity of viral diseases like dengue and chikungunya fevers. mosquito midgut is considered to be an important site for host-pathogen interaction and pathogen survival is thought to be an outcome of this interaction. in the present study we examined the bacterial community in the midgut of aedes mosquitoes in arunanchal pradesh, india, a subtropical zone where dengue fever is rep ... | 2015 | 26684012 |
| optimized use of the maldi biotyper system and the filmarray bcid panel for direct identification of microbial pathogens from positive blood cultures. | despite the current reliance on blood cultures (bcs), the diagnosis of bloodstream infections (bsis) can be sped up using new technologies performed directly on positive bc bottles. two methods (the maldi biotyper system and filmarray blood culture identification [bcid] panel) are potentially applicable. in this study, we performed a large-scale clinical evaluation (1,585 microorganisms from 1,394 bsi episodes) on the combined use of the maldi biotyper and filmarray bcid panel compared to a refe ... | 2016 | 26677254 |
| rapid detection of oxa-48-producing enterobacteriaceae by matrix-assisted laser desorption ionization-time of flight mass spectrometry. | a rapid and sensitive (100%) matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) assay was developed to detect oxa-48-type producers, using 161 previously characterized clinical isolates. ertapenem was monitored to detect carbapenem resistance, and temocillin was included in the assay as a marker for oxa-48-producers. structural analysis of temocillin is described. data are obtained within 60 min. | 2016 | 26677247 |
| the microbiome of diabetic foot osteomyelitis. | the purpose of this investigation was to evaluate the diversity of bacteria in diabetic foot osteomyelitis using a 16s rrna sequencing approach and to compare the results with conventional culture techniques. in this prospective observational study, we obtained 34 bone samples from patients admitted to our hospital with a moderate-severe diabetic foot infection. we analysed the distribution of the 16s rrna gene sequences in the bone samples, using an illumina miseq personal sequencer. we compare ... | 2015 | 26670675 |
| the microbiome of diabetic foot osteomyelitis. | the purpose of this investigation was to evaluate the diversity of bacteria in diabetic foot osteomyelitis using a 16s rrna sequencing approach and to compare the results with conventional culture techniques. in this prospective observational study, we obtained 34 bone samples from patients admitted to our hospital with a moderate-severe diabetic foot infection. we analysed the distribution of the 16s rrna gene sequences in the bone samples, using an illumina miseq personal sequencer. we compare ... | 2015 | 26670675 |
| could cd64 expression be used as a predictor of positive culture results in children with febrile neutropenia? | early recognition of infectious processes in neutropenic patients is hampered by the fact that these processes may have dissimilar and non-specific clinical presentations. cd64 is a neutrophil surface marker that is not expressed in non-sensitized neutrophils. when the neutrophil is exposed to tumor necrosis factor-alpha it is activated and is measured via the cd64 index. | 2015 | 26670402 |
| an automated miniaturized method to perform and analyze antimicrobial drug synergy assays. | in the light of emerging antibiotic resistance mechanisms found in bacteria throughout the world, discovery of drugs that potentiate the effect of currently available antibiotics remains an important aspect of pharmaceutical research in the 21st century. well-established clinical tests exist to determine synergy in vitro, but these are only optimal for low-throughput experimentation while leaving analysis of results and interpretation of high-throughput microscale assays poorly standardized. her ... | 2016 | 26669516 |
| pathogenicity island cross talk mediated by recombination directionality factors facilitates excision from the chromosome. | pathogenicity islands (pais) are mobile integrated genetic elements (miges) that contain a diverse range of virulence factors and are essential in the evolution of pathogenic bacteria. pais are widespread among bacteria and integrate into the host genome, commonly at a trna locus, via integrase-mediated site-specific recombination. the excision of pais is the first step in the horizontal transfer of these elements and is not well understood. in this study, we examined the role of recombination d ... | 2016 | 26668266 |
| risk factors and outcomes for intestinal carriage of ampc-hyperproducing enterobacteriaceae in intensive care unit patients. | in a cohort of 1,209 intensive care unit (icu) patients, the prevalence of intestinal colonization with high-level expressed ampc cephalosporinase-producing enterobacteriaceae (hlac-pe) rose steadily from 2% at admission to 30% in patients with lengths of stay (los) exceeding 4 weeks. in multivariate analysis, los was the main predictor of carriage acquisition after adjustment on antimicrobial exposure. hlac-pe infection occurred in 15% of carriers. carriage and infection were associated with a ... | 2016 | 26666938 |
| β-lactamase characterization of gram-negative pathogens recovered from patients enrolled in the phase 2 trials for ceftazidime-avibactam: clinical efficacies analyzed against subsets of molecularly characterized isolates. | the correlation of the clinical efficacies of ceftazidime-avibactam and comparators (carbapenems) was evaluated against baseline gram-negative isolates having characterized β-lactam resistance mechanisms from complicated urinary tract infection (cuti) and complicated intra-abdominal infection (ciai) phase 2 trials. enterobacteriaceae displaying ceftriaxone and/or ceftazidime mics of ≥ 2 μg/ml (69 isolates) and nonfermentative gram-negative bacilli (nf-gnb [three isolates]) with ceftazidime mics ... | 2016 | 26666936 |
| correlation of β-lactamase production and colistin resistance among enterobacteriaceae isolates from a global surveillance program. | the increasing use of carbapenems for treating multidrug-resistant (mdr) gram-negative bacterial infections has contributed to the global dissemination of carbapenem-resistant enterobacteriaceae (cre). serine and metallo-β-lactamases (mbls) that hydrolyze carbapenems have become prevalent and endemic in some countries, necessitating the use of older classes of agents, such as colistin. a total of 19,719 isolates of enterobacteriaceae (excluding proteeae and serratia spp., which have innate resis ... | 2016 | 26666920 |
| comparison of verona integron-borne metallo-β-lactamase (vim) variants reveals differences in stability and inhibition profiles. | metallo-β-lactamases (mbls) are of increasing clinical significance; the development of clinically useful mbl inhibitors is challenged by the rapid evolution of variant mbls. the verona integron-borne metallo-β-lactamase (vim) enzymes are among the most widely distributed mbls, with >40 vim variants having been reported. we report on the crystallographic analysis of vim-5 and comparison of biochemical and biophysical properties of vim-1, vim-2, vim-4, vim-5, and vim-38. recombinant vim variants ... | 2016 | 26666919 |
| complete genome sequence of the molybdenum-resistant bacterium bacillus subtilis strain lm 4-2. | bacillus subtilis lm 4-2, a gram-positive bacterium was isolated from a molybdenum mine in luoyang city. due to its strong resistance to molybdate and potential utilization in bioremediation of molybdate-polluted area, we describe the features of this organism, as well as its complete genome sequence and annotation. the genome was composed of a circular 4,069,266 bp chromosome with average gc content of 43.83 %, which included 4149 predicted orfs and 116 rna genes. additionally, 687 transporter- ... | 2015 | 26664656 |
| mesaconase/fumarase fumd in escherichia coli o157:h7 and promiscuity of escherichia coli class i fumarases fuma and fumb. | mesaconase catalyzes the hydration of mesaconate (methylfumarate) to (s)-citramalate. the enzyme participates in the methylaspartate pathway of glutamate fermentation as well as in the metabolism of various c5-dicarboxylic acids such as mesaconate or l-threo-β-methylmalate. we have recently shown that burkholderia xenovorans uses a promiscuous class i fumarase to catalyze this reaction in the course of mesaconate utilization. here we show that classical escherichia coli class i fumarases a and b ... | 2015 | 26658641 |
| surgical site infections in a longitudinal cohort of neonatal intensive care unit patients. | to estimate the incidence and identify risk factors for surgical site infections (ssis) among infants in the neonatal intensive care unit (nicu). | 2015 | 26658124 |
| surgical site infections in a longitudinal cohort of neonatal intensive care unit patients. | to estimate the incidence and identify risk factors for surgical site infections (ssis) among infants in the neonatal intensive care unit (nicu). | 2015 | 26658124 |
| retrospective study on multidrug-resistant bacterium infections after rigid internal fixation of mandibular fracture. | to retrospectively investigate infection by multidrug-resistant bacteria (mdrb) after rigid internal fixation (rif) of mandibular fracture and determine risk factors and cure methods. | 2016 | 26657396 |
| urinary tract infection among renal transplant recipients in yemen. | urinary tract infection (uti) is the most common complication following kidney transplantation (kt), which could result in losing the graft. this study aims to identify the prevalence of bacterial uti among kt recipients in yemen and to determine the predisposing factors associated with post renal transplantation uti. a cross sectional study included of 150 patients, who underwent kt was conducted between june 2010 and january 2011. a morning mid-stream urine specimen was collected for culture a ... | 2015 | 26657128 |
| structural and functional analyses reveal insights into the molecular properties of the escherichia coli z ring stabilizing protein, zapc. | in escherichia coli cell division is driven by the tubulin-like gtpase, ftsz, which forms the cytokinetic z-ring. the z-ring serves as a dynamic platform for the assembly of the multiprotein divisome, which catalyzes membrane cleavage to create equal daughter cells. several proteins effect ftsz assembly, thereby providing spatiotemporal control over cell division. one important class of ftsz interacting/regulatory proteins is the z-ring-associated proteins, zaps, which typically modulate z-ring ... | 2015 | 26655719 |
| structural and functional analyses reveal insights into the molecular properties of the escherichia coli z ring stabilizing protein, zapc. | in escherichia coli cell division is driven by the tubulin-like gtpase, ftsz, which forms the cytokinetic z-ring. the z-ring serves as a dynamic platform for the assembly of the multiprotein divisome, which catalyzes membrane cleavage to create equal daughter cells. several proteins effect ftsz assembly, thereby providing spatiotemporal control over cell division. one important class of ftsz interacting/regulatory proteins is the z-ring-associated proteins, zaps, which typically modulate z-ring ... | 2015 | 26655719 |
| editorial: luxr solos are becoming major players in cell-cell communication in bacteria. | 2015 | 26649284 | |
| bacterial colonies in solid media and foods: a review on their growth and interactions with the micro-environment. | bacteria, either indigenous or added, are immobilized in solid foods where they grow as colonies. since the 80's, relatively few research groups have explored the implications of bacteria growing as colonies and mostly focused on pathogens in large colonies on agar/gelatine media. it is only recently that high resolution imaging techniques and biophysical characterization techniques increased the understanding of the growth of bacterial colonies, for different sizes of colonies, at the microscop ... | 2015 | 26648910 |
| optimizing polymyxin combinations against resistant gram-negative bacteria. | polymyxin combination therapy is increasingly used clinically. however, systematic investigations of such combinations are a relatively recent phenomenon. the emerging pharmacodynamic (pd) and pharmacokinetic (pk) data on cms/colistin and polymyxin b suggest that caution is required with monotherapy. given this situation, polymyxin combination therapy has been suggested as a possible way to increase bacterial killing and reduce the development of resistance. considerable in vitro data have been ... | 2015 | 26645096 |
| gut bacteria mediate aggregation in the german cockroach. | aggregation of the german cockroach, blattella germanica, is regulated by fecal aggregation agents (pheromones), including volatile carboxylic acids (vcas). we demonstrate that the gut microbial community contributes to production of these semiochemicals. chemical analysis of the fecal extract of b. germanica revealed 40 vcas. feces from axenic cockroaches (no microorganisms in the alimentary tract) lacked 12 major fecal vcas, and 24 of the remaining compounds were represented at extremely low a ... | 2015 | 26644557 |
| multiyear, multinational survey of the incidence and global distribution of metallo-β-lactamase-producing enterobacteriaceae and pseudomonas aeruginosa. | metallo-β-lactamases (mbls) hydrolyze all classes of β-lactams except monobactams and are not inhibited by classic serine β-lactamase inhibitors. gram-negative pathogens isolated from patient infections were collected from 202 medical centers in 40 countries as part of a global surveillance study from 2012 to 2014. carbapenem-nonsusceptible enterobacteriaceae and pseudomonas aeruginosa were characterized for bla genes encoding vim, imp, ndm, spm, and gim variants using pcr and sequencing. a tota ... | 2016 | 26643349 |
| molecular characterization by using next-generation sequencing of plasmids containing blandm-7 in enterobacteriaceae from calgary, canada. | enterobacteriaceae with blandm-7 are relatively uncommon and had previously been described in europe, india, the united states, and japan. this study describes the characteristics of enterobacteriaceae (klebsiella pneumoniae [n = 2], escherichia coli [n = 2], serratia marcescens [n = 1], and enterobacter hormaechei [n = 1] isolates) with blandm-7 obtained from 4 patients from calgary, canada, from 2013 to 2014. the 46,161-bp incx3 plasmids with blandm-7 are highly similar to other blandm-harbori ... | 2016 | 26643346 |
| role of residues w228 and y233 in the structure and activity of metallo-β-lactamase gim-1. | metallo-β-lactamases (mbls) hydrolyze virtually all β-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. the worldwide emergence of antibiotic-resistant bacteria harboring mbls poses an increasing clinical threat. the mbl german imipenemase-1 (gim-1) possesses an active site that is narrower and more hydrophobic than the active sites of other mbls. the gim-1 active-site groove is shaped by the presence of the aromatic side chains of tryptophan at residue 228 and tyrosine ... | 2016 | 26643332 |
| my 40-year history with cronobacter/enterobacter sakazakii - lessons learned, myths debunked, and recommendations. | much has been learned about organism in the cronobacter/enterobacter sakazakii complex since i first named and described enterobacter sakazakii in 1980. however, there are still wide knowledge gaps. one of the most serious is that are still many uncertainties associated with assessing the public health risk posed by these bacteria, particularly in neonatal meningitis. over the last few decades, cronobacter contamination of commercial powdered infant formula products has apparently been reduced, ... | 2015 | 26640778 |
| bloodstream infections due to enterobacteriaceae among neonates in poland--molecular analysis of the isolates. | bloodstream infections (bsis) are associated with a significantly increased risk of fatality. no report has been found about the molecular epidemiology of enterobacteriaceae causing bsi in neonates in poland. the aim of this work was to determine the antibiotic resistance profiles, virulence gene prevalence, the epidemiological and genetic relationships among the isolates from enterobacteriaceae causing bsi in neonates with birth weight < 1501 g. antimicrobial susceptibility testing was performe ... | 2015 | 26638530 |
| oxygen affects gut bacterial colonization and metabolic activities in a gnotobiotic cockroach model. | the gut microbiota of termites and cockroaches represents complex metabolic networks of many diverse microbial populations. the distinct microenvironmental conditions within the gut and possible interactions among the microorganisms make it essential to investigate how far the metabolic properties of pure cultures reflect their activities in their natural environment. we established the cockroach shelfordella lateralis as a gnotobiotic model and inoculated germfree nymphs with two bacterial stra ... | 2016 | 26637604 |
| evaluation of the byg carba test, a new electrochemical assay for rapid laboratory detection of carbapenemase-producing enterobacteriaceae. | accurate detection of carbapenemase-producing enterobacteriaceae (cpe) constitutes a major laboratory diagnostic challenge. we evaluated an electrochemical technique (the byg carba test) which allows detection of cpe in less than 35 min. the byg carba test was first validated in triplicate against 57 collection isolates with previously characterized β-lactam resistance mechanisms (oxa-48, n = 12; kpc, n = 8; ndm, n = 8; vim, n = 8; imp, n = 3; gim, n = 1; ges-6, n = 1; no carbapenemase, n = 16) ... | 2016 | 26637378 |
| synergic effects between ocellatin-f1 and bufotenine on the inhibition of bhk-21 cellular infection by the rabies virus. | rabies is an incurable neglected zoonosis with worldwide distribution characterized as a lethal progressive acute encephalitis caused by a lyssavirus. animal venoms and secretions have long been studied as new bioactive molecular sources, presenting a wide spectrum of biological effects, including new antiviral agents. bufotenine, for instance, is an alkaloid isolated from the skin secretion of the anuran rhinella jimi that inhibits cellular penetration by the rabies virus. antimicrobial peptide ... | 2015 | 26635873 |
| mass spectrometry-based method of detecting and distinguishing type 1 and type 2 shiga-like toxins in human serum. | shiga-like toxins (verotoxins) are responsible for the virulence associated with a variety of foodborne bacterial pathogens. direct detection of toxins requires a specific and sensitive technique. in this study, we describe a mass spectrometry-based method of analyzing the tryptic decapeptides derived from the non-toxic b subunits. a gene encoding a single protein that yields a set of relevant peptides upon digestion with trypsin was designed. the (15)n-labeled protein was prepared by growing th ... | 2015 | 26633510 |
| recovery of bacteria and fungi from a leg wound. | acute and chronic wound infections can both be encountered in the deployed setting. these wounds are often contaminated by bacteria and fungi derived from the external environment. in this article, we present the case of a wound infection simultaneously colonized by enterobacter cloacae (a bacterial pathogen) and trichosporon asahii (an unusual fungal pathogen). we describe the examination and treatment of the patient and review the distinguishing characteristics of each organism. | 2015 | 26630106 |
| the effect of infection control nurses on the occurrence of pseudomonas aeruginosa healthcare-acquired infection and multidrug-resistant strains in critically-ill children. | healthcare-acquired pseudomonas aeruginosa (p. aeruginosa) infections in the pediatric intensive care unit (picu), which have a high incidence, increase treatment costs and mortality, and seriously threaten the safety of critically ill children. it is essential to seek convenient and effective methods to control and prevent healthcare-acquired infections (hais). this research was conducted to study the effect of infection control nurses on the occurrence of p. aeruginosa hais and multi-drug resi ... | 2015 | 26630032 |
| clinical observation of antibiotics in preventing nosocomial infection in premature infants. | to study the possibility of lower the nosocomial infection rate among the premature infants by prophylactic use of antibiotics. | 2015 | 26629165 |
| revealing the characteristics of a novel bioflocculant and its flocculation performance in microcystis aeruginosa removal. | in the present work, a novel bioflocculant, eps-1, was prepared and used to flocculate the kaolin suspension and microcystis aeruginosa. we focused on the characteristics and flocculation performance of eps-1, especially with regard to its protein components. an important attribute of eps-1 was its protein content, with 18 protein types identified that occupied a total content of 31.70% in the eps-1. moreover, the flocculating activity of these protein components was estimated to be no less than ... | 2015 | 26626432 |
| metagenomic sequencing of bile from gallstone patients to identify different microbial community patterns and novel biliary bacteria. | despite the high worldwide prevalence of gallstone disease, the role of the biliary microbiota in gallstone pathogenesis remains obscure. next-generation sequencing offers advantages for systematically understanding the human microbiota; however, there have been few such investigations of the biliary microbiome. here, we performed whole-metagenome shotgun (wms) sequencing and 16s rrna sequencing on bile samples from 15 chinese patients with gallstone disease. microbial communities of most indivi ... | 2015 | 26625708 |
| high potential application in bioremediation of selenate by proteus hauseri strain qw4. | selenium is essential for biological systems at low concentrations and toxic at higher levels. heavy metals and metalloids such as selenium are major contaminants in 40% of hazardous waste sites. thus, bioremediation has been considered as an effective means of cleaning up of selenium-contaminated sites. | 2015 | 26622970 |
| detection of ampc β-lactamases in acinetobacter baumannii in the xuzhou region and analysis of drug resistance. | the aim of the present study was to determine the prevalence and related drug resistance of ampc β-lactamases in acinetobacter baumannii in tertiary-level hospitals in the xuzhou region in china. a total of 134 clinical isolates of non-repetitive acinetobacter baumannii were collected from different hospitals in the xuzhou region, and multiplex polymerase chain reaction (pcr) was employed to determine the genotype of ampc. the pcr products were purified and sequenced. the susceptibility to antib ... | 2015 | 26622417 |
| sucupira as a potential plant for arthritis treatment and other diseases. | trees of the genus pterodon, commonly known as "sucupira-branca" or "faveira," are native to central brazil. the pterodon fruits are traditionally used in ethnomedicine as an infusion, in small doses, and at regular time intervals as an antirheumatic, anti-inflammatory, tonic, and depurative agent. the various compounds present in the pterodon class are, generally, water-insoluble and derived from the fusion of high-molecular weight pentacarbonate units. scientific research has shown that the ma ... | 2015 | 26613051 |
| bioaugmentation of lactobacillus delbrueckii ssp. bulgaricus tistr 895 to enhance bio-hydrogen production of rhodobacter sphaeroides kku-ps5. | bioaugmentation or an addition of the desired microorganisms or specialized microbial strains into the anaerobic digesters can enhance the performance of microbial community in the hydrogen production process. most of the studies focused on a bioaugmentation of native microorganisms capable of producing hydrogen with the dark-fermentative hydrogen producers while information on bioaugmentation of purple non-sulfur photosynthetic bacteria (pnsb) with lactic acid-producing bacteria (lab) is still ... | 2015 | 26613000 |
| negative pressure incision management system in the prevention of groin wound infection in vascular surgery patients. | objectives. groin wounds following vascular surgery are highly susceptible to healing disturbances, with reported site infections reaching 30%. negative pressure incision management systems (npims) are believed to positively influence the prevention of surgical wound-healing disturbances (whd) and surgical site infections (ssi). npims placed directly after closure of the surgical wound is thought to result in fewer infections; we analysed its effect on postoperative wound infections in patients ... | 2015 | 26609543 |
| epidemiologic and genotypic review of carbapenemase-producing organisms in british columbia, canada, between 2008 and 2014. | carbapenemase-producing organisms (cpos) are a serious emerging problem for health care facilities worldwide. owing to their resistance to most antimicrobial therapies, cpos are difficult to treat and pose a challenge for infection prevention and control. since 2010, lab-based surveillance for cpos and pcr-based testing were implemented in british columbia (bc), canada. a review of cpos in bc from 2008 to march 2014 was done to characterize the resistance mechanisms and possible clonal strain tr ... | 2016 | 26607987 |
| use of an enrichment broth improves detection of extended-spectrum-beta-lactamase-producing enterobacteriaceae in clinical stool samples. | this study evaluated the impact of preenrichment on the detection of extended-spectrum beta-lactamase-producing enterobacteriaceae (esbl-e) in clinical stool samples. esbl-e were detected in 41 of 343 patients (12.0%). as 31.7% of the esbl-e carriers were identified by preenrichment, only this additional diagnostic step significantly improved the detection of esbl-e. | 2016 | 26607984 |
| evaluation of an immunochromatographic lateral flow assay (oxa-48 k-set) for rapid detection of oxa-48-like carbapenemases in enterobacteriaceae. | we evaluated an immunochromatographic lateral flow assay to detect oxa-48-like carbapenemases (oxa-48 k-set) in enterobacteriaceae (n = 82). one hundred percent sensitivity and specificity were observed using bacteria recovered from both solid medium and spiked blood culture bottles, and the results were obtained in <10 min. | 2016 | 26607983 |
| detection of carbapenemase production in a collection of enterobacteriaceae with characterized resistance mechanisms from clinical and environmental origins by use of both carba np and blue-carba tests. | rapid-screening methods to confirm the presence of resistance mechanisms in multidrug-resistant bacteria are currently recommended. carba np and blue-carba tests were evaluated in carbapenemase-producing enterobacteriaceae from hospital (n = 102) and environmental (n = 57) origins for detecting the different molecular classes among them. both methods showed to be fast and cost-effective, with high sensitivity (98% to 100%) and specificity (100%), and may be easily introduced in the routine labor ... | 2016 | 26607979 |
| first identification of an imi-1 carbapenemase-producing colistin-resistant enterobacter cloacae in china. | carbapenem resistance among the enterobacteriaceae is a serious healthcare challenge. bla imi is a carbapenemase gene mediating resistance to carbapenems but has not been commonly found. a bla imi-carrying enterobacter cloacae, which was also resistant to colistin, is reported here. | 2015 | 26607057 |
| discovery of a mcl-pha with unexpected biotechnical properties: the marine environment of french polynesia as a source for pha-producing bacteria. | a library of microorganisms originating from various marine environments in french polynesia was screened for polyhydroxyalkanoate producing bacteria. no significant connection was found between the geo-ecological source of bacteria and their ability to produce polyhydroxyalkanoate. a bacterial strain designated as enterobacter fak 1384 was isolated from a shark jaw. when grown on coprah oil, this bacterium produces a pha constituting of 62 mol % 3-hydroxydecanoate and lower amount of 12 mol % 3 ... | 2015 | 26606919 |
| bacterial ecology of fermented cucumber rising ph spoilage as determined by nonculture-based methods. | fermented cucumber spoilage (fcs) characterized by rising ph and the appearance of manure- and cheese-like aromas is a challenge of significant economical impact for the pickling industry. previous culture-based studies identified the yeasts pichia manshurica and issatchenkia occidentalis, 4 gram-positive bacteria, lactobacillus buchneri, lactobacillus parrafaraginis, clostridium sp., and propionibacterium and 1 gram-negative genus, pectinatus, as relevant in various stages of fcs given their ab ... | 2015 | 26605993 |
| bacterial ecology of fermented cucumber rising ph spoilage as determined by nonculture-based methods. | fermented cucumber spoilage (fcs) characterized by rising ph and the appearance of manure- and cheese-like aromas is a challenge of significant economical impact for the pickling industry. previous culture-based studies identified the yeasts pichia manshurica and issatchenkia occidentalis, 4 gram-positive bacteria, lactobacillus buchneri, lactobacillus parrafaraginis, clostridium sp., and propionibacterium and 1 gram-negative genus, pectinatus, as relevant in various stages of fcs given their ab ... | 2015 | 26605993 |
| detection of esbl- and ampc-producing e. coli isolates from urinary tract infections. | extended-spectrum β-lactamases (esbls) and ampc enzymes have been observed in virtually all species of the family enterobacteriaceae. the β-lactamase producing bacteria cause many serious infections, including urinary tract infections. these enzymes are predominantly plasmid mediated. there are no recommended guidelines for detection of this resistance mechanism and there is a need to address this issue as much as the detection of esbls. this study was undertaken to characterize esbl and ampc pr ... | 2015 | 26605249 |
| impact of a modified broviac maintenance care bundle on bloodstream infections in paediatric cancer patients. | during intensive chemotherapy, bloodstream infection (bsi) represents an important complication in paediatric cancer patients. most patients carry a long-term central venous access device (cvad). improved maintenance care of these vascular catheters may decrease the risk of bsi. | 2015 | 26605135 |
| predictors of bacteraemia in patients with suspected community-acquired pneumonia. | the diagnostic yield of blood cultures is limited in patients with community-acquired pneumonia (cap). yet, positive blood culture results provide important information for antibiotic treatment and for monitoring epidemiologic trends. we investigated the potential of clinical predictors to improve the cost-benefit ratio of obtaining blood cultures. | 2015 | 26599636 |
| red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients. | this study evaluated the possible prebiotic effect of a moderate intake of red wine polyphenols on the modulation of the gut microbiota composition and the improvement in the risk factors for the metabolic syndrome in obese patients. ten metabolic syndrome patients and ten healthy subjects were included in a randomized, crossover, controlled intervention study. after a washout period, the subjects consumed red wine and de-alcoholized red wine over a 30 day period for each. the dominant bacterial ... | 2016 | 26599039 |
| animal-microbe interactions and the evolution of nervous systems. | animals ubiquitously interact with environmental and symbiotic microbes, and the effects of these interactions on animal physiology are currently the subject of intense interest. nevertheless, the influence of microbes on nervous system evolution has been largely ignored. we illustrate here how taking microbes into account might enrich our ideas about the evolution of nervous systems. for example, microbes are involved in animals' communicative, defensive, predatory and dispersal behaviours, and ... | 2016 | 26598731 |
| report on a transborder spread of carbapenemase-producing bacteria by a patient injured during euromaidan, ukraine. | spread of carbapenemase-producing bacteria has been described all over the world. this phenomenon may be accelerated by many factors, including wars and natural disasters. in this report, we described an ndm-1-producing klebsiella pneumonia st11 recovered from a patient injured during the maidan revolution in ukraine. to our knowledge, this is the first report of a carbapenemase-producing enterobacteriaceae in ukraine and one of several reports describing wound colonization/infection of humans i ... | 2015 | 26594376 |
| prospective comparison of a pcr assay and a microbiological culture technique for identification of pathogens from blood and non-blood samples in septic patients. | molecular amplification techniques are suggested to be a useful adjunct in early detection of pathogens in septic patients. the aim was to study the feasibility of a polymerase chain reaction (pcr) assay compared to the standard microbiological culture (mc) technique in identification of pathogenic microorganisms from blood and non-blood samples in septic patients. | 2015 | 26594362 |
| biofilm models of polymicrobial infection. | interactions between microbes are complex and play an important role in the pathogenesis of infections. these interactions can range from fierce competition for nutrients and niches to highly evolved cooperative mechanisms between different species that support their mutual growth. an increasing appreciation for these interactions, and desire to uncover the mechanisms that govern them, has resulted in a shift from monomicrobial to polymicrobial biofilm studies in different disease models. here w ... | 2015 | 26592098 |
| in vitro antibacterial and antibiotic-potentiation activities of the methanol extracts from beilschmiedia acuta, clausena anisata, newbouldia laevis and polyscias fulva against multidrug-resistant gram-negative bacteria. | the present study was designed to investigate the antibacterial activities of the methanol extracts from different parts of beilschmedia acuta kosterm (lauraceae), clausena anisata (willd) hook (rutaceae), newbouldia laevis seem (bignoniaceae) and polyscias fulva (hiern) harms (araliaceae) as well as their synergistic effects with antibiotics against a panel of gram-negative bacteria, including multi-drug resistant (mdr) phenotypes expressing active efflux pumps. | 2015 | 26590804 |
| identification of a novel nematotoxic protein by challenging the model mushroom coprinopsis cinerea with a fungivorous nematode. | the dung of herbivores, the natural habitat of the model mushroom coprinopsis cinerea, is a nutrient-rich but also very competitive environment for a saprophytic fungus. we showed previously that c. cinerea expresses constitutive, tissue-specific armories against antagonists such as animal predators and bacterial competitors. in order to dissect the inducible armories against such antagonists, we sequenced the poly(a)-positive transcriptome of c. cinerea vegetative mycelium upon challenge with f ... | 2015 | 26585824 |
| identification of a novel nematotoxic protein by challenging the model mushroom coprinopsis cinerea with a fungivorous nematode. | the dung of herbivores, the natural habitat of the model mushroom coprinopsis cinerea, is a nutrient-rich but also very competitive environment for a saprophytic fungus. we showed previously that c. cinerea expresses constitutive, tissue-specific armories against antagonists such as animal predators and bacterial competitors. in order to dissect the inducible armories against such antagonists, we sequenced the poly(a)-positive transcriptome of c. cinerea vegetative mycelium upon challenge with f ... | 2015 | 26585824 |
| arthropod vectors and disease transmission: translational aspects. | 2015 | 26583380 | |
| evaluation of an image analysis device (apas) for screening urine cultures. | while advancements have been made in some areas of pathology with diagnostic materials being screened using image analysis technologies, the reporting of cultures from agar plates remains a manual process. we compared the results for 2,163 urine cultures read by a reference panel of microbiologists, by the routine laboratory process, and by an automated plate reading system, apas (lbt innovations ltd., south australia). apas detected colonies with a sensitivity of 99.1% and a specificity of 99.3 ... | 2016 | 26582838 |
| comparative study of a novel biochemical assay, the rapidec carba np test, for detecting carbapenemase-producing enterobacteriaceae. | the novel biochemical test, the rapidec carba np (rcnp), was evaluated using carbapenemase- and non-carbapenemase-producing enterobacteriaceae isolates. the rcnp test was compared with the carba np test (cnp) and the modified hodge test. compared to the cnp test, the rcnp test had identical sensitivity (96%) and lower specificity (93% versus 100%). the medium used to culture the isolates significantly affected test sensitivity and specificity. the rcnp test was quicker and easier to perform than ... | 2016 | 26582833 |
| local injection of aminoglycosides for prophylaxis against infection in open fractures. | the purpose of this study was to determine the efficacy of local wound cavity injections of aqueous aminoglycosides (gentamicin and tobramycin), in conjunction with systemic antibiotics, to lower the prevalence of infection in patients with open fractures. | 2015 | 26582614 |
| multiplex detection of nine food-borne pathogens by mpcr and capillary electrophoresis after using a universal pre-enrichment medium. | routine microbiological quality analyses in food samples require, in some cases, an initial incubation in pre-enrichment medium. this is necessary in order to ensure that small amounts of pathogenic strains are going to be detected. in this work, a universal pre-enrichment medium has been developed for the simultaneous growth of bacillus cereus, campylobacter jejuni, clostridium perfringens, cronobacter sakazakii, escherichia coli, enterobacteriaceae family (38 species, 27 genera), listeria mono ... | 2015 | 26579100 |
| impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: an opportunity for stewardship. | respiratory viruses are increasingly recognized as significant etiologies of pneumonia among hospitalized patients. advanced technologies using multiplex molecular assays and polymerase-chain reaction increase the ability to identify viral pathogens and may ultimately impact antibacterial use. | 2015 | 26577540 |
| synergy and mode of action of ceftazidime plus quercetin or luteolin on streptococcus pyogenes. | streptococcus pyogenes causes streptococcal toxic shock syndrome. the recommended therapy has been often failure through the interfering of beta-lactamase-producing bacteria (blpb). the present study was to investigate antibacterial activity, synergy, and modes of action of luteolin and quercetin using alone and plus ceftazidime against s. pyogenes. the mics of ceftazidime, luteolin, and quercetin against all s. pyogenes were 0.50, 128, and 128 µg ml(-1), respectively. a synergistic effect was e ... | 2015 | 26576195 |
| in vitro antimicrobial activity of a siderophore cephalosporin, s-649266, against enterobacteriaceae clinical isolates, including carbapenem-resistant strains. | s-649266 is a novel siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. two sets of clinical isolate collections were used to evaluate the antimicrobial activity of s-649266 against enterobacteriaceae. these sets included 617 global isolates collected between 2009 and 2011 and 233 β-lactamase-identified isolates, including 47 kpc-, 49 ndm-, 12 vim-, and 8 imp-producers. the mic90 values of s-649266 against the first set of escherichia coli, klebsiella pneumo ... | 2016 | 26574013 |
| characteristics of a novel aerobic denitrifying bacterium, enterobacter cloacae strain hnr. | a novel aerobic denitrifier strain hnr, isolated from activated sludge, was identified as enterobacter cloacae by16s rrna sequencing analysis. glucose was considered as the most favorable c-source for strain hnr. the logistic equation well described the bacterial growth, yielding a maximum growth rate (μmax) of 0.283 h(-1) with an initial no3 (-)-n concentration of 110 mg/l. almost all no3 (-)-n was removed aerobically within 30 h with an average removal rate of 4.58 mg n l(-1) h(-1). nitrogen b ... | 2016 | 26573667 |
| [screening probiotic endophytic bacteria from medicinal plant flex cornuta and the phytopathogen-inhibiting effect]. | culturable endophytic bacteria were isolated from medicinal plant ilex cornuta by plate-spreading method, strains with strong inhibitory effect on phytopathogen were screened by confrontation culture and fermentation filtrate culture methods, and the morphological changes of phytopathogen hyphae treated with endophytic bacteria were examined by microscopy and micrograph. their phylogenetic relationships were determined by homology analysis of the 16s rdna sequences of pcr products and the taxono ... | 2015 | 26571677 |
| analysis of glycosylated hemoglobin (hba1c) level on maxillofacial fascial space infection in diabetic patients. | this study was performed to evaluate the impact of glycosylated hemoglobin (hba1c) level on characteristics and prognosis of maxillofacial fascial infection in diabetic patients. | 2015 | 26568927 |
| genome sequence and description of pantoea septica strain ff5. | strain ff5 was isolated from the skin flora of a healthy senegalese 35-year-old woman. this strain was identified as belonging to the species pantoea septica based on rpob sequence identity of 99.7 % with pantoea septica strain lmg 5345(t) and a highest maldi-tof-ms score of 2.3 with pantoea septica. like p. septica, this ff5 strain is a gram-negative, aerobic, motile, and rod-shaped bacterium. currently, 17 genomes have been sequenced within the genus pantoea but none for pantoea septica. herei ... | 2015 | 26568786 |
| prevalence and molecular characterizations of enterovirus d68 among children with acute respiratory infection in china between 2012 and 2014. | ev-d68 is associated with respiratory tract infections (rtis). since its first isolation, ev-d68 has been detected sporadically. however, the us and canada have experienced outbreaks of ev-d68 infections between august and december 2014. this study aimed to investigate the molecular epidemiology and clinical characteristics of ev-d68 in chongqing, southwestern china. from january 2012 to november 2014, 1876 nasopharyngeal aspirate specimens (npas) were collected from hospitalized children with r ... | 2015 | 26568267 |
| epidemiology and outcome of trichosporon fungemia: a review of 185 reported cases from 1975 to 2014. | background. trichosporon species have emerged as an important non-candida spp yeast pathogen in immunocompromised patients in recent decades; however, the systemic analysis of trichosporon epidemiology has seldom been reported. methods. we reviewed 185 reported cases of trichosporon fungemia from 1975 to 2014 in the english-language literature, and the epidemiology and prognostic factors of the included cases are described. results. the number of cases reported has increased with time, especi ... | 2015 | 26566536 |
| about the usefulness of contact precautions for carriers of extended-spectrum beta-lactamase-producing escherichia coli. | extended-spectrum β-lactamases producing escherichia coli (esbl-e) are increasingly identified in health care facilities. as previously done for the control of methicillin-resistant staphylococcus aureus, many hospitals have established screening strategies for early identification of patients being carriers of esbl producers in general and esbl-e in particular, and have implemented contact precautions (cp) for infected and colonized patients. | 2015 | 26563141 |
| larval ecology of anopheles coluzzii in cape coast, ghana: water quality, nature of habitat and implication for larval control. | there is a growing interest in larval control intervention to supplement existing malaria control strategies, particularly in urban areas. however, effective implementation requires a good understanding of habitat ecology of anopheles mosquitoes. clean water bodies have long been reported by several studies as a preferred breeding habitat for anopheles gambiae. other studies have also reported the breeding of an. gambiae in polluted water bodies. however, the term clean or polluted is mostly bas ... | 2015 | 26558365 |
| diversity of culturable bacterial endophytes of saffron in kashmir, india. | saffron (crocus sativus) is a medicinally important plant. the kashmir valley (j&k, india) emblematizes one of the major and quality saffron producing areas in the world. nonetheless, the area has been experiencing a declining trend in the production of saffron during the last decade. poor disease management is one of the major reasons for declining saffron production in the area. endophytes are known to offer control against many diseases of host plant. during the present study, culturable bact ... | 2015 | 26558164 |