Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| discovery of parasite eggs in archeological residence during the 15th century in seoul, korea. | during civil engineering construction near sejong-ro, jongro-ku, seoul, cultural sites were found that are thought to have been built in the 15th century. this area was home to many different people as well as the leaders of the yi dynasty. to gain further insight into the life styles of the inhabitants of the old capital, soil samples were collected from various areas such as toilets, water foundations, and drainage ways. parasite eggs were examined by microscopy after 5 g soil samples were reh ... | 2017 | 28719964 |
| recent incidence of paragonimus westermani metacercariae in freshwater crayfish, cambaroides similis, from two enzootic sites in jeollanam-do, korea. | an epidemiological study was performed to know the recent infection status of paragonimus westermani metacercariae (pwmc) in freshwater crayfish, cambaroides similis, from 2 streams in jeollanam-do, republic of korea. crayfish were collected from creeks in bogil-do (island), wando-gun, and in a creek near daeheung temple in haenam-gun. the infection rate of crayfish with pwmc in bogil-do was 89.8%, and the metacercarial burden was 37 pwmc per the infected crayfish. crayfish in a creek near daehe ... | 2017 | 28719962 |
| a case of ectopic peritoneal paragonimiasis mimicking diverticulitis or abdominal abscess. | paragonimiasis is a parasitic disease caused by paragnonimus species. the primary site of infection is the lung, and extrapulmonary involvement is also reported. when infected with paragonimus westermani, which is the dominant species in korea, the central nervous system is frequently involved along with the liver, intestine, peritoneal cavity, retroperitoneum, and abdominal wall. ectopic paragonimiasis raises diagnostic challenge since it is uncommon and may be confused with malignancy or other ... | 2017 | 28719956 |
| infection with paragonimus westermani of boar-hunting dogs in western japan maintained via artificial feeding with wild boar meat by hunters. | infection of boar-hunting dogs with paragonimus westermani was investigated in western japan. blood and rectal feces were collected from 441 dogs in the three districts (205 in kinki, 131 in chugoku and 105 in shikoku district). in a screening elisa for serum antibody against p. westermani antigen, 195 dogs (44.2%) showed positive reaction. in the 195 dogs, 8 dogs were found excreting p. westermani eggs after molecular analysis of fecal eggs, and additional 7 were identified serologically for th ... | 2017 | 28717056 |
| delineating distinct heme-scavenging and binding functions of domains in mf6p/hdm proteins from parasitic flatworms. | mf6p/fhhdm-1 is a small protein secreted by the parasitic flatworm (trematode) fasciola hepatica and belonging to a broad family of heme-binding proteins (mf6p/hdms). mf6p/hdms are of interest for understanding heme homeostasis in trematodes and also as potential targets for the development of new flukicides. moreover, interest in these molecules has also increased due to their immunomodulatory properties. here we have extended our previous findings on the mechanism of mf6p/hdm-heme interactions ... | 2017 | 28348084 |
| inactivation of paragonimus westermani metacercariae in soy sauce-marinated and frozen freshwater crabs. | soy sauce-marinated freshwater crabs (eriocheir japonicus) are a source of human paragonimiasis. the viability of paragonimus westermani metacercariae (pwmc) in marinated crabs was investigated in an experimental setting. the pwmc collected from freshwater crayfish were inoculated into freshwater crabs, which were then frozen or marinated in soy sauce. all pwmc in the freshwater crabs were inactivated after freezing for 48 h at -20 °c and after freezing for 12 h at -40 °c. after marinating for 3 ... | 2017 | 28127717 |
| familial mediterranean fever with rheumatoid arthritis complicated by pulmonary paragonimiasis. | a 42-year-old woman presented with an intermittent fever and chest and back pain, and an abnormal chest shadow was detected. she was diagnosed with paragonimiasis caused by paragonimus westermani. praziquantel therapy improved the abnormal chest shadow, but did not relieve her symptoms. she was also diagnosed with familial mediterranean fever (fmf), and colchicine therapy resolved her symptoms. she subsequently developed arthralgia and morning stiffness in her hands. we also diagnosed the patien ... | 2017 | 27725555 |
| venison, another source of paragonimus westermani infection. | paragonimiasis is a typical food-borne parasitic disease, endemic in most parts of asia, with sporadic case reports from american and african countries. the major source of infection is undercooked freshwater crab or crayfish, though consumption of wild boar meat is also responsible for the infection in japan, because wild boar is a paratenic host for paragonimus westermani. recently, living juveniles of p. westermani were isolated from muscle of a sika deer, cervus nippon, in japan, raising the ... | 2016 | 27644890 |
| conservation and diversification of the transcriptomes of adult paragonimus westermani and p. skrjabini. | paragonimiasis is an important and widespread neglected tropical disease. fifteen paragonimus species are human pathogens, but two of these, paragonimus westermani and p. skrjabini, are responsible for the bulk of human disease. despite their medical and economic significance, there is limited information on the gene content and expression of paragonimus lung flukes. | 2016 | 27619014 |
| two cases of paragonimiasis westermani diagnosed after eosinophilic pleural effusion-induced hydropneumothorax. | our hospital is located in the tono region in the southeastern district of gifu prefecture in which there are forests and inhabitants who still hunt and eat game meat. therefore, boar meat increases the risk of contracting paragonimiasis. we treated two patients who were infected by paragonimus westermani after eating boar meat. they developed hydropneumothorax in association with eosinophilic pleural effusion. for patients who have pneumothorax with concomitant pleural effusion and eosinophilia ... | 2016 | 27516883 |
| paragonimus westermani infection mimicking recurrent lung cancer: a case report. | herein, we report a case of paragonimus westermani infection, which required differentiation from recurrent lung cancer. a 66-year old japanese man with a history of lung cancer who had undergone a lobectomy was referred to our clinic for treatment of cough, sputum, dyspnea, and a right pulmonary nodule. he had previously eaten seafood he visited china. p. westermani infection was confirmed by the presence of antibody against p. westermani antigen in the patient's serum and eggs in his sputum. e ... | 2016 | 27498617 |
| molecular and morphological variation of paragonimus westermani in vietnam with records of new second intermediate crab hosts and a new locality in a northern province. | paragonimus westermani is one of the most medically important lung flukes and is widely distributed in asia. it exhibits considerable variation in morphological, genetic and biological features. in central provinces of vietnam, a high prevalence of metacercariae of this species has been reported from the crab intermediate host, vietopotamon aluoiense. in this study, we detected p. westermani metacercariae in two additional crab hosts, donopotamon haii in quang tri province, central vietnam and i ... | 2016 | 27440217 |
| a tool for mass-screening of paragonimiasis: an enzyme-linked immunosorbent assay with urine samples. | paragonimiasis is one of the foodborn trematodiases and number of the patients was estimated to be about 23 million around the world. to obtain good compliance of people for the surveillance of paragonimiasis, an enzyme-linked immunosorbent assay (elisa) for the diagnosis of paragonimiasis with unconcentrated urine samples was developed. | 2016 | 27433138 |
| endemic hemoptysis. | 2007 | 27407988 | |
| paragonimus kellicotti: a lung infection in our own backyard. | paragonimiasis is an infection caused by the lung fluke of the genus paragonimus. within the united states, paragonimiasis has been commonly diagnosed in southeast asian immigrants infected with the asian lung fluke paragonimus westermani. infections from the north american lung fluke, paragonimus kellicotti, have been rare, although more infections have been seen in people in the midwestern united states. a 29-year-old male with a history of pleomorphic xanthoastrocytoma presented with hemoptys ... | 2016 | 27213066 |
| pulmonary paragonimiasis mimicking tuberculous pleuritis: a case report. | pulmonary paragonimiasis is a food-borne zoonosis with a wide variety of radiologic findings, which sometimes can be confused with tuberculosis and carcinoma. therefore, differential diagnosis is always warranted. a 43-year-old male farmer, with productive cough, blood-tinged sputum and chest pain, as well as patchy consolidation and pleural effusions in chest computer tomography, was misdiagnosed of community-acquired pneumonia and tuberculosis. complete blood cell count, sputum smear and cultu ... | 2016 | 27082624 |
| electromagnetic navigational bronchoscopy spares a drunken crab from the surgeon's knife. | surgical resection is traditionally the preferred treatment for fluorodeoxyglucose-avid peripheral pulmonary nodules that grow over time. however, new technologies, including electromagnetic navigational bronchoscopy (enb), provide an opportunity to confirm or possibly exclude a cytologic cancer diagnosis, before resection. we present a case of a 56-year-old north american man who presented with a fluorodeoxyglucose-avid pulmonary nodule and sought a second opinion after being recommended thorac ... | 2016 | 27070338 |
| demographic characteristic and analysis of pulmonary paragonimiasis in patients attending rims, manipur. | human infection by the lung fluke paragonimus westermani is widely distributed in africa, asia, and south america. transmission of the parasite to humans primarily occurs through the consumption of raw or undercooked crabs. clinical features of recently diagnosed pulmonary paragonimiasis show that patients present with a variety of clinical and radiological findings, frequently mimics tuberculosis and lung cancer. | 2017 | 27051099 |
| pulmonary paragonimiasis: the detection of a worm migration track as a diagnostic clue for uncertain eosinophilic pleural effusion. | a 38-year-old woman with sustained right chest pain was referred to our hospital. she showed pleural effusion and peripheral blood eosinophilia. thoracentesis revealed eosinophilic pleural effusion in which the smear, culture and cytological examinations were all negative. although she had no notable dietary history, chest ct revealed linear opacities, which suggested the migration tracks of paragonimiasis. the diagnosis was confirmed using enzyme-linked immunosorbent assays, which showed elevat ... | 2016 | 26935371 |
| collection methods of trematode eggs using experimental animal models. | although observing the eggs of human parasitic helminth is essential for medical education in parasitology, opportunities for collection of the eggs are limited. collection of the eggs using experimental animal models is needed for a sustainable supply. the metacercariae of three trematode species, paragonimus westermani, clonorchis sinensis and metagonimus yokogawai, were collected from the second intermediate hosts: freshwater crabs and fishes, which were obtained using online shopping in japa ... | 2016 | 26792074 |
| [establishment of duplex pcr for identifying metagonimus yokogawai and haplorchis taichui]. | to develop a duplex pcr method for identifying metagonimus yokogawai and haplorchis taichui. | 2015 | 26541032 |
| elevated serum igg4 levels in two cases of paragonimiasis. | paragonimiasis is a parasitic pleuropulmonary infection caused by eating raw crustaceans and wild boar meat and this infection is endemic in asia. we herein report two cases of pulmonary p aragonimus westermani infection associated with elevated levels of serum immunoglobulin (ig) g4 and dense infiltration of igg4-positive plasma cells in the lung lesions. treatment with praziquantel resolved the pulmonary lesions and decreased the serum levels of igg4. igg4-related disease is a systemic disease ... | 2015 | 26392854 |
| images in clinical medicine. hemoptysis associated with paragonimus westermani. | 2015 | 26267642 | |
| evaluation of the mgl method to detect paragonimus eggs and its improvement. | dog feces containing 500 paragonimus westermani eggs per gram were examined by the medical general laboratory (mgl), the simple sedimentation (ss), and the army medical school iii (ams iii) methods. the number of eggs per gram of feces (epg) obtained by the mgl method was 17.2 and was significantly lower than those obtained by the ss method (324.0) and the ams iii method (505.6). when isolated p. westermani eggs were processed by the mgl method and four layers (ether, ether-fecal, formalin layer ... | 2015 | 26243572 |
| [pathogens of human trematodiases in the primorye territory]. | the primorye territory of russia is part of a natural habitat for pathogens of four human trematodiases: metagonimiasis (caused by the two worms metagonimus yokogawai and m. katsuradai in the region), nanophyetiasis (nanophyetus salmincola schikhobalowi), paragonimiasis (paragonimus westermani ishunensis), and clonorchiasis (clonorchis sinensis). the tensest situation in the region has emerged with clonorchiasis, the pathogen of which is extending its area due to anthropogenic sources. in additi ... | 2015 | 26152030 |
| paragonimus westermani infection in lung: a confounding diagnostic entity. | paragonimiasis is a food-borne parasitic zoonosis caused by the genus paragonimus. fresh water snails, crabs, and crayfish are the first and second intermediate hosts, respectively. humans acquire this infection by ingesting uncooked/undercooked crustaceans. laboratory diagnosis of paragonimiasis is done by demonstration of ova in the sputum/feces/pleural fluid or by serology. a case of pulmonary paragonimiasis is presented herewith; the patient having been diagnosed with pulmonary tuberculosis ... | 2017 | 25983414 |
| [analysis on parasitic infection of clinical samples from hospitals in shanghai during 2011-2013]. | to analyze the results of parasitic pathogen detection on clinical samples from shanghai hospitals during 2011-2013. | 2014 | 25902676 |
| [two cases of paragonimiasis westermani in a chinese family diagnosed with the ouchterlony double diffusion method]. | we report two cases of paragonimus westermani infection in a chinese family in japan. a 41-year-old husband and his 40-year-old wife were infected with p. westermani after consuming a homemade chinese traditional "drunken crab." they were a family with two children who had lived in japan for 19 years. the crabs were eriocheir japonica sent from the kyusyu area that they had pickled at home with soy sauce and chinese liquor for 5 days. their children did not eat any of the crabs. one month after ... | 2014 | 25764810 |
| first case of paragonimus westermani infection in a female patient in india. | paragonimiasis is a foodborne parasitic zoonosis caused by lung fluke species of the genus paragonimus. the paragonimus westermani is the most common human pathogen in asian countries. in northeast india, paragonimus heterotremus has been documented as the only human pathogen in the earlier literature. in india, p. westermani infection in humans remained undetermined. herein, we report a case of pulmonary paragonimiasis due to p. westermani in an adult female in manipur. the diagnosis was made b ... | 2015 | 25657140 |
| molecular and biochemical characterization of paragonimus westermani tyrosinase. | trematode tyrosinases (tyrs) play a major role in the tanning process during eggshell formation. we investigated the molecular and biochemical features of paragonimus westermani tyr (pwtyr). the pwtyr cdna was composed of 1568-bp encompassing a 1422-bp-long open reading frame (474-amino acid polypeptide). a strong phylogenetic relationship with platyhelminthes and deuterostomian orthologues was evident. the recombinant pwtyr expressed in prokaryotic cells promptly oxidized diphenol substrates, w ... | 2015 | 25621413 |
| cerebral paragonimiasis: an unusual manifestation of a rare parasitic infection. | paragonimiasis is a parasitic disease that typically produces a subacute to chronic inflammatory disease of the lung. although rare in the united states, paragonimiasis is sporadically observed in the immigrant population. rarely, paragonimiasis can affect the nervous system. this infection is even more unusual in the pediatric population, and therefore can be challenging to diagnose. | 2015 | 25556153 |
| cerebral paragonimiasis: a retrospective analysis of 27 cases. | the authors retrospectively analyzed the clinical characteristics, existing problems, and treatment experiences in recently diagnosed cerebral paragonimiasis (cp) cases and sought to raise awareness of cp and to supply reference data for early diagnosis and treatment. | 2015 | 25380173 |
| a case of delayed diagnosis of pulmonary paragonimiasis due to improvement after anti-tuberculosis therapy. | here, we report a case of pulmonary paragonimiasis that was improved with initial anti-tuberculosis (tb) therapy but confused with reactivated pulmonary tb. a 53-year-old chinese female presented with a persistent productive cough with foul smelling phlegm and blood streaked sputum. radiologic findings showed subpleural cavitary consolidation in the right upper lobe (rul). bronchoscopic and cytological examination showed no remarkable medical feature. she was diagnosed with smear-negative tb, an ... | 2014 | 25368664 |
| cutaneous paragonimiasis due to triploid paragonimus westermani presenting as a non-migratory subcutaneous nodule: a case report. | paragonimiasis is a food-borne infection caused by paragonimus parasites. the lungs and pleura are the primary sites for the infection; however, ectopic infection can occur in other organs such as skin, liver and brain. it is difficult to make a diagnosis of ectopic paragonimiasis due to an ignorance of, and unfamiliarity with the disease. we report the case of a patient with subcutaneous paragonimiasis diagnosed by histopathological analysis and serological testing. | 2014 | 25322860 |
| expression characteristics and specific antibody reactivity of diverse cathepsin f members of paragonimus westermani. | paragonimiasis, caused by the lung fluke paragonimus, is a major food-borne helminthic disease. differential diagnosis of paragonimiasis from tuberculosis and other infectious granulomas in the lung is a prerequisite to proper management of patients. cysteine proteases of paragonimus westermani (pwcps) invoke specific antibody responses against patient sera, while antibody capturing activity of different pwcps has not been comparatively analyzed. in this study, we observed the expressional regul ... | 2015 | 25284814 |
| the mitochondrial genome of paragonimus westermani (kerbert, 1878), the indian isolate of the lung fluke representative of the family paragonimidae (trematoda). | among helminth parasites, paragonimus (zoonotic lung fluke) gains considerable importance from veterinary and medical points of view because of its diversified effect on its host. nearly fifty species of paragonimus have been described across the globe. it is estimated that more than 20 million people are infected worldwide and the best known species is paragonimus westermani, whose type locality is probably india and which infects millions of people in asia causing disease symptoms that mimic t ... | 2014 | 25165620 |
| [case report; a case of two female siblings with paragonimus westermani infection]. | 2014 | 24908996 | |
| metagonimus yokogawai: a 100-kda somatic antigen commonly reacting with other trematodes. | this study was undertaken to characterize the properties of a 100 kda somatic antigen from metagonimus yokogawai. monoclonal antibodies (mabs) were produced against this 100 kda antigen, and their immunoreactivity was assessed by western blot analysis with patients' sera. the mabs against the 100 kda antigen commonly reacted with various kinds of trematode antigens, including intestinal (gymnophalloides seoi), lung (paragonimus westermani), and liver flukes (clonorchis sinensis and fasciola hepa ... | 2014 | 24850966 |
| [investigation on the hosts with natural paragonimus infection and species identification in jinhua prefecture of zhejiang province]. | to investigate the natural hosts infected with paragonimus sp. and identify the species of the parasite in selected counties/districts of jinhua prefecture in zhejiang province. | 2011 | 24830196 |
| evaluation of recombinant sjlap and sjfbpa in detecting antibodies to schistosoma japonicum. | to investigate the early response of immunoglobulin g (igg) antibody responses to schistosoma japonicum infection in mice by using the recombinant proteins, s. japonicum leucine aminopeptidase (rsjlap) and s. japonicum fructose-1, 6-bisphosphate aldolase (rsjfbpa), and evaluate the potential of rsjlap and rsjfbpa in diagnosis as well as in assessment of therapeutic efficacy in human schistosomiasis. | 2011 | 24830194 |
| use of purified antigen for detection of paragonimus westermani and clonorchis sinensis in peoples of hsinchu hsien, taiwan (formosa). | 1960 | 24545964 | |
| evaluation of igg4 subclass antibody detection by peptide-based elisa for the diagnosis of human paragonimiasis heterotrema. | a synthetic peptide was prepared based on the antigenic region of paragonimus westermani pre-procathepsin l, and its applicability for immunodiagnosis for human paragonimiasis (due to paragonimus heterotremus) was tested using an elisa to detect igg4 antibodies in the sera of patients. sera from other helminthiases, tuberculosis, and healthy volunteers were used as the references. this peptide-based assay system gave sensitivity, specificity, accuracy, and positive and negative predictive values ... | 2013 | 24516288 |
| paragonimus and paragonimiasis in vietnam: an update. | paragonimiasis is a food-borne parasitic zoonosis caused by infection with lung flukes of the genus paragonimus. in vietnam, research on paragonimus and paragonimiasis has been conducted in northern and central regions of the country. using a combination of morphological and molecular methods, 7 paragonimus species, namely p. heterotremus, p. westermani, p. skrjabini, p. vietnamensis, p. proliferus, p. bangkokenis and p. harinasutai, have been identified in vietnam. of these, the first 3, p. het ... | 2013 | 24516264 |
| regulation of anti-inflammatory cytokines il-10 and tgf-β in mouse dendritic cells through treatment with clonorchis sinensis crude antigen. | dendritic cells (dcs), which are regarded as the most potent antigen-presenting cells, are involved in innate and adaptive immunity. upon uptake of pathogens, dcs express cell surface markers and secrete cytokines. in this study, we analyzed production of cytokines and found that interleukin (il)-10 and transforming growth factor (tgf)-β production significantly increased in bone marrow-derived dcs and a mouse dc line, dc2.4, after treatment with crude antigen (ca) from liver fluke, clonorchis s ... | 2014 | 24480801 |
| the role of y84 on domain 1 and y87 on domain 2 of paragonimus westermani taurocyamine kinase: insights on the substrate binding mechanism of a trematode phosphagen kinase. | the two-domain taurocyamine kinase (tk) from paragonimus westermani was suggested to have a unique substrate binding mechanism. we performed site-directed mutagenesis on each domain of this tk and compared the kinetic parameters km(tc) and vmax with that of the wild-type to determine putative amino acids involved in substrate recognition and binding. replacement of y84 on domain 1 and y87 on domain 2 with r resulted in the loss of activity for the substrate taurocyamine. y84e mutant has a dramat ... | 2013 | 24184078 |
| [detection of four parasitic infections using elisa]. | to study the detection effects of elisa for the infections of cysticercus, echinococcosus, paragonimus westermani and sparganum mansoni in order to improve diagnosis. | 2013 | 24024464 |
| [effect comparison between two elisa kits in igg antibody detection of echinococcus granulosus]. | to compare the effects of two elisa kits on igg antibody detection of human echinococcus granulosus. | 2013 | 24024450 |
| [geographic distribution and gene sequencing of paragonimus westermani in some areas of guangdong province]. | to investigate the current distribution of paragonimus westermani in guangdong province. | 2013 | 24024448 |
| the changing pattern of parasitic infection among korean populations by paleoparasitological study of joseon dynasty mummies. | in the coprolites of 4 recently discovered joseon mummies of korea, we found ascaris lumbricoides , trichuris trichiura , metagonimus yokogawai , paragonimus westermani , and clonorchis sinensis eggs. the current finding was compared with previous paleoparasitological data, and with recent national survey data from korea. for a. lumbricoides and t. trichiura , similar patterns of infection prevalence were observed between the national survey of 1961 and our current joseon data. some of the trema ... | 2014 | 24011353 |
| development of a polymerase chain reaction applicable to rapid and sensitive detection of clonorchis sinensis eggs in human stool samples. | microscopic examination of eggs of parasitic helminths in stool samples has been the most widely used classical diagnostic method for infections, but tiny and low numbers of eggs in stool samples often hamper diagnosis of helminthic infections with classical microscopic examination. moreover, it is also difficult to differentiate parasite eggs by the classical method, if they have similar morphological characteristics. in this study, we developed a rapid and sensitive polymerase chain reaction ( ... | 2013 | 23916334 |
| paragonimiasis. | human paragonimiasis is caused by nine species of paragonimus, namely, p. westermani, p. africanus, p. heterotremus, p. kellicotti, p. mexicanus, p. siamensis, p. skrjabini, p. skrjabini miyazakii, and p. uterobilateralis. cerebral or spinal involvements are most common in p. westermani, and can also occur in p. skrjabini, p. skrjabini miyazakii, and p. mexicanus. in p. westermani, cerebral paragonimiasis comprises about 45% of all extrapulmonary paragonimiasis cases, and accounts for about 1% o ... | 2013 | 23829919 |
| gene structure of the two-domain taurocyamine kinase from paragonimus westermani: evidence for a distinct lineage of trematode phosphagen kinases. | taurocyamine kinase (tk) is an enzyme that catalyzes the reversible transfer of a phosphate between atp and taurocyamine. annelid tks were suggested to have evolved from a ck ancestor. however, tks from the lung fluke paragonimus westermani comprised another lineage. construction of phylogenetic tree and comparison of exon/intron organization showed that p. westermani tk and other trematode tks evolved from a molluscan arginine kinase (ak) gene. exon shuffling probably caused the changes in amin ... | 2013 | 23751729 |
| serological diagnosis of north american paragonimiasis by western blot using paragonimus kellicotti adult worm antigen. | abstract. we studied the value of an igg western blot (wb) with paragonimus kellicotti (pk) antigen for diagnosis of north american paragonimiasis. the test was evaluated with sera from patients with pk and paragonimus westermani infections, with control sera from patients with other helminth infections, and sera from healthy americans. all 11 proven pk infection sera and two samples from suspected cases that were negative by p. westermani wb at the centers for disease control and prevention (cd ... | 2013 | 23589531 |
| genetic variability among dicrocoelium dendriticum isolates from different regions in shaanxi province, china revealed by sequences of three mitochondrial genes. | the genetic variations in three mitochondrial dna (mtdna) regions, namely portion of cytochrome c oxidase subunit 1 (pcox1), nadh dehydrogenase subunit 1 (pnad1) and cytochrome b (pcytb), were examined for dicrocoelium dendriticum samples isolated from different origins in shaanxi province, northwestern china. the intra-specific sequence differences within d. dendriticum samples were 0-0.52% for pcox1, 0-0.73% for pnad1 and 0-0.58% for pcytb. phylogenetic analyses based on combined sequences of ... | 2013 | 23521316 |
| pleuropulmonary paragonimiasis: mimicker of tuberculosis. | infection caused by the lung fluke is endemic in north eastern parts of india. paragonimus westermani and paragonimus heterotremus are known to be endemic in eastern indian states of manipur and nagaland. the infection is related to eating habits of the locals and is acquired by ingestion of raw, inadequately cooked crabs or crayfish containing encysted metacercariae which act as second intermediate hosts during the life cycle of the lung fluke. diagnosis is generally delayed due to lack of susp ... | 2013 | 23432864 |
| molecular identification of paragonimus species by dna pyrosequencing technology. | dna pyrosequencing for pcr amplicons is an attractive strategy for the identification of microorganisms because of its short time performance for large number of samples. in this study, the primers targeting the fragment of its2 region of nuclear ribosomal rna gene were newly developed for pyrosequencing-based identification of 6 paragonimus species, paragonimus bangkokensis, paragonimus harinasutai, paragonimus heterotremus, paragonimus macrorchis, paragonimus siamensis and paragonimus westerma ... | 2013 | 23246361 |
| intestinal paragonimiasis with colonic ulcer and hematochezia in an elderly taiwanese woman. | a 94-year-old female with end-stage renal disease presents with fever, fatigue, and hematochezia. she had previously resided in hunan province, china, and myanmar, and she immigrated to taiwan 30 years ago. colonoscopy revealed a colonic ulcer. biopsy of the colonic ulcer showed ulceration of the colonic mucosa, and many paragonimus westermani-like eggs were noted. serum igg antibody levels showed strong reactivity with p. westermani excretory-secretory antigens by elisa. intestinal paragonimias ... | 2012 | 23230334 |
| a protein microarray for the rapid screening of patients suspected of infection with various food-borne helminthiases. | food-borne helminthiases (fbhs) have become increasingly important due to frequent occurrence and worldwide distribution. there is increasing demand for developing more sensitive, high-throughput techniques for the simultaneous detection of multiple parasitic diseases due to limitations in differential clinical diagnosis of fbhs with similar symptoms. these infections are difficult to diagnose correctly by conventional diagnostic approaches including serological approaches. | 2012 | 23209851 |
| parasitoses of the human central nervous system. | cerebral involvement in parasitoses is an important clinical manifestation of most of the human parasitoses. parasites that have been described to affect the central nervous system (cns), either as the dominant or as a collateral feature, include cestodes (taenia solium (neurocysticerciasis), echinococcus granulosus (cerebral cystic echinococcosis), e. multilocularis (cerebral alveolar echinococcosis), spirometra mansoni (neurosparganosis)), nematodes (toxocara canis and t. cati (neurotoxocarias ... | 2013 | 23046708 |
| parasitic diseases of the pleura. | parasitic infections are prevalent in certain parts of the world and may cause pleural involvement, which often goes unrecognized. common parasites involving the pleura include entamoeba histolytica, echinococcus granulosus and paragonimus westermani. amebiasis can cause empyema with "anchovy sauce" pus, reactive pleural effusions and bronchopleural fistula with hydropneumothorax. echinococcosis may result in pleural thickening, pneumothorax, secondary pleural hydatidosis and pleural effusions. ... | 2013 | 22990049 |
| presence of three distinct genotypes within the paragonimus westermani complex in northeastern india. | the name paragonimus westermani (kerbert, 1878) is commonly applied to members of a species complex that includes the well-known asian lung fluke of medical and veterinary importance. unambiguous molecular and morphological evidence showing the presence of a member of the complex in india has recently been published. in the present study we report the occurrence of 2 more members of the p. westermani complex in northeastern (ne) india. surveys of the freshwater crabs maydelliatelphusa lugubris i ... | 2013 | 22917216 |
| pleuropulmonary and abdominal paragonimiasis: ct and ultrasound findings. | the purpose of this study was to review radiological images of patients with paragonimus westermani (pw) that simultaneously involved the chest and abdomen. | 2012 | 22457403 |
| co-existence of paragonimus harinasutai and paragonimus bangkokensis metacercariae in fresh water crab hosts in central viet nam with special emphasis on their close phylogenetic relationship. | during our epidemiological surveys for paragonimus species in central viet nam, we found four morphologically different paragonimus metacercariae in mountainous crabs. they were identified as metacercariae of paragonimus westermani, p. bangkokensis, p. proliferus, and p. harinasutai in the order of their prevalence in crab hosts. this is the first discovery of p. harinasutai in viet nam, co-inhabiting with p. bangkokensis and other species. metacercariae of p. harinasutai were given orally to a ... | 2012 | 22329917 |
| serine protease inhibitors of parasitic helminths. | serine protease inhibitors (serpins) are a superfamily of structurally conserved proteins that inhibit serine proteases and play key physiological roles in numerous biological systems such as blood coagulation, complement activation and inflammation. a number of serpins have now been identified in parasitic helminths with putative involvement in immune regulation and in parasite survival through interference with the host immune response. this review describes the serpins and smapins (small seri ... | 2012 | 22310379 |
| characterization and differential expression of a ferritin protein from fasciola hepatica. | ferritins are proteins that play a central role in maintaining intracellular iron balance. a cdna clone of fasciola hepatica (687 bp long) encoding a putative 228-amino acid polypeptide (fhftn-1) homologous with ferritins of vertebrates and invertebrates was identified. fhftn-1 contains a conserved motif of the ferroxidase center typical of vertebrate ferritins. phylogenetic tree analysis showed that fhftn-1 clusters with two ferritins of paragonimus westermani, which suggests a common ancestry ... | 2011 | 22240114 |
| loop-mediated isothermal amplification (lamp): early detection of toxoplasma gondii infection in mice. | abstract: background: toxoplasmosis is a widespread zoonotic parasitic disease that occurs in both animals and humans. traditional molecular assays are often difficult to perform, especially for the early diagnosis of toxoplasma gondii infections. here, we established a novel loop-mediated isothermal amplification targeting the 529 bp repeat element (529 bp-lamp) to detect t. gondii dna in blood samples of experimental mice infected with tachyzoites of the rh strain. findings: the assay was pe ... | 2012 | 22214421 |
| Serological diagnosis of clonorchiasis: using a recombinant propeptide of cathepsin L proteinase from Clonorchis sinensis as a candidate antigen. | Clonorchiasis is a common zoonosis in southern and northeastern parts of China, especially in Guangdong, Guangxi and Jilin province. Anti-Clonorchis sinensis antibody detection by enzyme-linked immunosorbent assay (ELISA) has been used for epidemiological surveys of clonorchiasis for its convenience and celerity, but it is still a meaningful work to screen ideal diagnostic antigen or antibody subtype for improvement of diagnostic sensitivity and specificity and for judgement of curative effect. ... | 2011 | 22173451 |
| Loop-mediated isothermal amplification: rapid detection of Angiostrongylus cantonensis infection in Pomacea canaliculata. | Angiostrongylus cantonensis is a zoonotic parasite that causes eosinophilic meningitis in humans. The most common source of infection with A. cantonensis is the consumption of raw or undercooked mollusks (e.g., snails and slugs) harbouring infectious third-stage larvae (L3). However, the parasite is difficult to identify in snails. The purpose of this study was to develop a quick, simple molecular method to survey for A. cantonensis in intermediate host snails. | 2011 | 22023992 |
| Chylothorax caused by Paragonimus westermani in a native Californian. | Paragonimiasis is a parasitic infection endemic in Asia but uncommon in the United States. It presents most frequently with cough and hemoptysis. Pleural effusions are common and can manifest occasionally as a pseudochylothorax, but a true chylothorax has, to our knowledge, never been reported. We report a case of a chylothorax from infection with Paragonimus westermani. The case is also unique because it occurred in a native Californian who had not traveled to Asia and was infected by eating ra ... | 2011 | 21972385 |
| Human paragonimiasis in Viet Nam: epidemiological survey and identification of the responsible species by DNA sequencing of eggs in patients' sputum. | Parasitological and sero-epidemiological surveys for human paragonimiasis were conducted in three provinces of Viet Nam. A total of 590 participants from two known endemic areas of human paragonimiasis (Sinho district of Laichau province and Lucyen district of Yenbai province) and from Dakrong district of Quangtri province where we recently found crab hosts heavily infected with Paragonimus westermani metacercariae. By multiple dot-ELISA screening, 28 (12.7%) out of 220 participants in Sinho dis ... | 2011 | 21946337 |
| a fluke occurrence of paramount significance. | 2011 | 21941073 | |
| paragonimus worm from a new guinea native in 1926. | to reobserve and research the specimen of paragonimus worm found in the left lung of a new guinea native in 1926, which was previously identified as paragonimus westermani kerbert or paragonimus ringeri cobbold. | 2011 | 21771422 |
| sequences and gene organization of the mitochondrial genomes of the liver flukes opisthorchis viverrini and clonorchis sinensis (trematoda). | opisthorchis viverrini and clonorchis sinensis are important trematodes infecting humans and animals, belonging to the family opisthorchiidae. in the present study, we sequenced the nearly complete mitochondrial (mt) dna (mtdna) sequences of o. viverrini from laos, obtained the complete mtdna sequences of c. sinensis from china and korea, and revealed their gene annotations and genome organizations. the mtdna sequences of o. viverrini, c. sinensis (china isolate), c. sinensis (korea isolate) wer ... | 2011 | 21626421 |
| [a case of paragonimus westermani with elevated fdg uptake into a pulmonary nodular lesion and right hilar and mediastinal lymph nodes on fdg-positron-emission tomography]. | a 47-year-old chinese woman living in japan was referred with a 2-month history of cough with hemoptysis. 18f-fluorodeoxyglucose-positron emission tomography (fdg-pet) showed increased fdg uptake into a pulmonary nodular lesion 25 mm in greatest dimension in the right upper lobe, and right hilar and mediastinal lymph nodes. laboratory investigation did not reveal either eosinophilia or a marked elevation of serum ige titer. a culture of bronchial lavage fluid was sterile and culture for mycobact ... | 2011 | 21591459 |
| pcr-based molecular characterization and insilico analysis of food-borne trematode parasites paragonimus westermani, fasciolopsis buski and fasciola gigantica from northeast india using its2 rdna. | food-borne fluke infections/trematodiases are emerging as a major public health problem worldwide with over 40 million people affected and over 10% of world population at risk of infection. the major concentration of these infections is in southeast asian and western pacific regions, where the epidemiological factors (including the prevalent socio-cultural food habits) are conducive for transmission of these infections. the preponderance of these infections is usually in food deficit poor commun ... | 2011 | 21544167 |
| development of a double antibody sandwich elisa assay for the diagnosis of angiostrongyliasis. | abstract abstractusing two monoclonal antibodies (mabs) against excretory/secretory (es) antigens of angiostrongylus cantonensis adult worms, a method of double antibody sandwich elisa for the detection of circulating antigens (cag) was established with the best experimental conditions regulated for performance. to evaluate the sensitivity, the cag in sera of rats (80) and mice (15) infected with a. cantonensis as well as cag in sera of clinical confirmed angiostrongyliasis patients (70) were de ... | 2011 | 21506824 |
| a paragonimiasis patient with allergic reaction to praziquantel and resistance to triclabendazole: successful treatment after desensitization to praziquantel. | paragonimiasis is an infectious disease caused by trematodes of the genus paragonimus. this trematode can be treated successfully with praziquantel in more than 90% of the cases. although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases. we report here a 46-year-old korean female with paragonimiasis, presumed to be due to paragonimus westermani, who displayed an allergic reaction to praziquantel and resistance to triclabendazole trea ... | 2011 | 21461273 |
| a pulmonary paragonimiasis case mimicking metastatic pulmonary tumor. | pulmonary paragonimiasis is a relatively rare cause of lung disease revealing a wide variety of radiologic findings, such as air-space consolidation, nodules, and cysts. we describe here a case of pulmonary paragonimiasis in a 27-year-old woman who presented with a 2-month history of cough and sputum. based on chest computed tomography (ct) scans and fluorodeoxyglucose positron emission tomography (fdg-pet) findings, the patient was suspected to have a metastatic lung tumor. however, she was dia ... | 2011 | 21461272 |
| pleuropulmonary infection by paragonimus westermani in the united states: a rare cause of eosinophilic pneumonia after ingestion of live crabs. | infections caused by the parasite paragonimus westermani are endemic to southeast asia. most infections reported in the united states are among immigrants who acquired the disease abroad. due to the nonspecific nature of its presentation and rarity in the united states, the diagnosis may first be suggested by the pathologist on biopsy review. definitive diagnosis may need serologic testing for confirmation. we report 4 cases of pleuropulmonary disease caused by united states-acquired p. westerma ... | 2011 | 21415702 |
| imaging features of intradural spinal paragonimiasis: a case report. | spinal paragonimiasis is a rare form of ectopic infestation caused by paragonimus westermani. we report a case of pathologically proven intradural paragonimiasis associated with concurrent intracranial involvement. mri revealed multiple well-defined intradural masses that were markedly hypointense on t(2) weighted images and hypointense with a peripheral hyperintense rim on t(1) weighted images. contrast-enhanced t(1) weighted images showed slight peripheral rim enhancement. | 2011 | 21415296 |
| pleuropulmonary paragonimiasis with intrathoracic mass. | pleuropulmonary paragonimiasis is a food-borne parasitic disease caused by the lung fluke paragonimus westermani or other species of paragonimus, which is endemic in southeast asia. it presents mainly pleural effusion or intrapulmonary nodules with respiratory symptoms. however, here we describe an exceedingly rare case of paragonimus westermani with a mass in the pleural cavity. a 47-year-old man, who had presented with chest pain nine months earlier, was found to have right pleural effusion on ... | 2010 | 21263427 |
| [food and parasitic infections]. | 2010 | 21228514 | |
| [two new species of freshwater crabs (decapoda: potamidae) serving as intermediate hosts of paragonimus in fujian, china]. | to investigate the natural resources of the freshwater crab which can serve as the intermediate hosts of paragonimus in pinghe and youxi of fujian province. | 2010 | 21137304 |
| sensitive and rapid detection of paragonimus westermani infection in humans and animals by loop-mediated isothermal amplification (lamp). | in the present study, a loop-mediated isothermal amplification (lamp) assay was developed and validated for the detection of paragonimus westermani adults, metacercariae, and eggs in human and animal samples. the lamp amplification can be finished in 45 min under isothermal condition at 60°c by employing a set of four species-specific primer mixtures and the results can be checked by naked-eye visualization. no amplification products were detected with deoxyribunucleic acid (dna) of related trem ... | 2010 | 21107864 |
| monoclonal antibodies against excretory/secretory antigens of angiostrongylus cantonensis. | in the present study, four murine monoclonal antibodies (mabs) were generated against the excretory/secretory (es) products of angiostrongylus cantonensis adult worms; two represented igg1 and two represented igm mabs, and they were designated 12d5, 15f8, 21b7 and 14g10, respectively. immunoblotting revealed that all of the mabs predominantly recognized a 98 kda antigen in the es products of a. cantonensis adult worms, and no cross reactions were found with the whole worm antigens of some other ... | 2010 | 21050048 |
| helminthic infections mimicking malignancy: a review of published case reports. | infectious diseases, including infections with helminths, can initially present similarly to malignancies. the goal of the article is to review reports of helminthic infections that are initially diagnosed as malignancy. | 2010 | 20818089 |
| seroprevalence of tissue invading parasitic infections diagnosed by elisa in korea. | seroprevalence of the igg antibodies for clonorchis sinensis, paragonimus westermani, taenia solium metacestode (cysticercus), and spirometra erinacei plerocercoid (sparganum) was measured using enzyme-linked immunosorbent assay (elisa) in sera of patients in korea from 1993 to 2006. a total of 74,448 specimens referred nationwide from 121 hospitals revealed an igg positive rate of 7.6% for the 4 parasites. the igg positive rate (18.7%) for the 4 parasites in 1993 decreased gradually to 6.6% in ... | 2010 | 20808668 |
| paragonimus westermani possesses aerobic and anaerobic mitochondria in different tissues, adapting to fluctuating oxygen tension in microaerobic habitats. | we previously showed that adult paragonimus westermani, the causative agent of paragonimiasis and whose habitat is the host lung, possesses both aerobic and anaerobic respiratory chains, i.e., cyanide-sensitive succinate oxidase and nadh-fumarate reductase systems, in isolated mitochondria (takamiya et al., 1994). this finding raises the intriguing question as to whether adult paragonimus worms possess two different populations of mitochondria, one having an aerobic succinate oxidase system and ... | 2010 | 20716443 |
| hepatic paragonimiasis revealed by fdg pet/ct. | a 72-year-old asymptomatic man with a hepatic lesion incidentally detected by ultrasonography in routine examination undertook fluorodeoxyglucose (fdg)-positron emission tomography/computed tomography for further evaluation. the images revealed increased fdg activity in the lesion, which was suggestive of malignancy. however, the pathologic examination demonstrated that the lesion was a granuloma caused by paragonimus westermani, a lung fluke. although increased fdg activity in the lung due to p ... | 2010 | 20706055 |
| paragonimus westermani found in the tip of a little finger. | paragonimiasis is the infestation of lung flukes of the trematode genus paragonimus. because the symptoms and radiologic findings of paragonimiasis mimic those of tuberculosis, some patients with paragonimiasis are initially treated for tuberculosis. although paragonimus may also reach ectopic sites such as the peritoneum or brain, infection in the skin is rare. to our knowledge, paragonimiasis has not been found in the tip of a finger. we report a case of 39-year-old woman who was belatedly dia ... | 2010 | 20686307 |
| effectiveness of mefloquine against clonorchis sinensis in rats and paragonimus westermani in dogs. | the aim of the study is to explore the effect of mefloquine against clonorchis sinensis and paragonimus westermani. for anti-c. sinensis study, a total of 71 rats were divided into four batches for oral infection of each rat with 50 c. sinensis metacercariae. five to 7 weeks post-infection, groups of rats were treated orally with mefloquine at single doses or multiple daily doses while infected, but untreated rats served as control. all treated rats were euthanized 2 weeks post-treatment for ass ... | 2010 | 20680332 |
| morphological and molecular characterization of paragonimus westermani in northeastern india. | evidence for the presence of lung flukes of the paragonimus westermani in india remains scant. in particular, evidence based on morphology of adult worms is lacking. metacercariae of the genus paragonimus, recovered from crabs in two regions of northeastern india, were raised to adulthood in laboratory rats. morphologically, these worms appear to be p. westermani. dna sequences from the second internal transcribed spacer (its2) and a portion of the ribosomal large subunit gene (28s) of the nucle ... | 2010 | 20493821 |
| [a case of paragonimus westermani complicated empyema by streptococcus pneumoniae]. | a 75-year-old man, who had eaten wild boar and deer repeatedly until november 2006, visited our hospital because of a right pleural effusion on chest x-ray films after he bruised a hip in january 2007. a right thoracocentesis revealed exudative pleural effusion with many neutrophils. ten days after his first visit, a pleural biopsy specimen suggested the existence of parasite eggs. twenty-six days after his first visit, he was admitted to our hospital because of leukocytosis, increased systemic ... | 2010 | 20432969 |
| paragonimiasis in a person whose symptoms were shown 22 years after emigrating to japan from laos. | we report a patient, a 52-year-old man from laos, who had come to japan at 30 years of age, but had maintained a habit of eating raw freshwater crabs. the patient visited a physician for left chest pain in january 2007. infiltration and mass-like shadows were noted in the left superior and inferior lobes on chest x-ray. diagnosis could not be made by bronchial brushing, but eggs were present in sputum cytology 3 days after bronchoscopy. therefore, paragonimiasis was diagnosed. the peripheral eos ... | 2010 | 20066554 |
| [paragonimus westermani infection confirmed by the detection of paragonimus ova in the sputum with bilateral pleural effusion]. | a 28-year-old man had a 1-year history of hemoptysis. consequently, he underwent a medical examination. a right pleural effusion, left hydropneumothorax, and multiple pulmonary nodular shadows were found on chest radiography. during a detailed interview, he reported that the hemoptysis began after eating "kejang" (a raw crab preparation) with a friend a year previously. his peripheral blood eosinophil count and serum ige level were elevated. in addition, ova were detected in the sputum and bilat ... | 2009 | 20058692 |
| paragonimus westermani: identification and characterization of the fasciclin i domain-containing protein. | paragonimus westermani is a trematode parasite that causes inflammatory lung disease as well as systemic infections in carnivorous mammals. the interaction of the parasite with host cells and paired worms is initiated by adhesion and plays an important role in parasite proliferation and differentiation. in this study, we isolated a cdna encoding a p. westermani fasciclin i domain-containing protein (pwfas-i). the fasiclin-i domain is suggested to be involved in cell adhesion, migration, and diff ... | 2010 | 20045688 |
| infection status of freshwater crabs and crayfish with metacercariae of paragonimus westermani in korea. | the present study investigated the infection status of paragonimus westermani metacercariae in freshwater crabs (n = 363) and crayfish (n = 31) from october 2007 to october 2008 using the crush method. all of the freshwater crabs, eriocheir japonicus, were negative for p. westermani metacercariae while 10 (32.3%) of the 31 examined crayfish were positive. the 10 positive crayfish were caught in haenam, jeollanam-do, and there were 8-59 (mean 28.4) metacercariae per infected crayfish. these resul ... | 2009 | 19967096 |
| phylogenetic reconstruction using secondary structures and sequence motifs of its2 rdna of paragonimus westermani (kerbert, 1878) braun, 1899 (digenea: paragonimidae) and related species. | most phylogenetic studies using current methods have focused on primary dna sequence information. however, rna secondary structures are particularly useful in systematics because they include characteristics that give "morphological" information, not found in the primary sequence. in several mountainous regions of northeastern india, foci of paragonimus (lung fluke) infection reportedly involve species that are known to prevail in neighbouring countries. the present study was undertaken to demon ... | 2009 | 19958489 |
| review of zoonotic parasites in medical and veterinary fields in the republic of korea. | zoonotic parasites are animal parasites that can infect humans. the major zoonotic protozoa in the republic of korea are babesia bovis, chilomastix mesnili, cryptosporidium parvum, endolimax nana, entamoeba coli, entamoeba hitolytica, giardia lamblia, iodamoeba bütschlii, pneumocystis carinii, sarcocystis cruzi, and toxoplasma gondii. the major zoonotic helminths in korea include trematodes, cestodes, and nematodes. trematodes are clonorchis sinensis, echinostoma hortense, echinostoma spp., fasc ... | 2009 | 19885329 |
| [paragonimiasis westermani associated with pseudochylothorax]. | a 67-year-old woman was referred to our hospital because of right pleural effusion. she had eaten boiled crab, eriocheir japonicus, raw crab of an unknown species, and broiled wild boar several years ago. the punctured pleural fluid was characterized by an exudative nature, milky-white color, and high cholesterol concentration, indicating pseudochylothorax. high titers of anti-paragonimus westermani antibody in the pleural fluid and serum, assessed by microplate elisa, established the diagnosis ... | 2009 | 19882911 |