Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| characterization of a feline influenza a(h7n2) virus. | during december 2016-february 2017, influenza a viruses of the h7n2 subtype infected ā500 cats in animal shelters in new york, ny, usa, indicating virus transmission among cats. a veterinarian who treated the animals also became infected with feline influenza a(h7n2) virus and experienced respiratory symptoms. to understand the pathogenicity and transmissibility of these feline h7n2 viruses in mammals, we characterized them in vitro and in vivo. feline h7n2 subtype viruses replicated in the resp ... | 2018 | 29260686 |
| harmful algal bloom-associated illnesses in humans and dogs identified through a pilot surveillance system - new york, 2015. | cyanobacteria, also known as blue-green algae, are photosynthetic, aquatic organisms found in fresh, brackish, and marine water around the world (1). rapid proliferation and accumulation of potentially toxin-producing cyanobacteria characterize one type of harmful algal bloom (hab). habs have the potential to cause illness in humans and animals (2,3); however, the epidemiology of these illnesses has not been well characterized. statewide in 2015, a total of 139 habs were identified in new york, ... | 2017 | 29095808 |
| case report: a cluster of three leptospirosis cases in a new york city abattoir and an unusual complication in the index case. | we report the case of a 46-year-old male abattoir worker who developed myalgias, shortness of breath, and irritability 2 weeks after sustaining a laceration to the hand with a knife at work. during his hospital evaluation for septic shock he was noted to be febrile, hypotensive, profoundly jaundiced with aseptic meningitis, and renal failure, and was diagnosed withleptospirosis interrogansinfection confirmed by serum and urine polymerase chain reaction. after standard antibiotic therapy and reco ... | 2017 | 29016310 |
| a novel a(h7n2) influenza virus isolated from a veterinarian caring for cats in a new york city animal shelter causes mild disease and transmits poorly in the ferret model. | in december 2016, a low-pathogenic avian influenza (lpai) a(h7n2) virus was identified to be the causative source of an outbreak in a cat shelter in new york city, which subsequently spread to multiple shelters in the states of new york and pennsylvania. one person with occupational exposure to infected cats became infected with the virus, representing the first lpai h7n2 virus infection in a human in north america since 2003. considering the close contact that frequently occurs between companio ... | 2017 | 28515300 |
| [arboviruses also have an american dream]. | some arboviruses that originated in the old world have been introduced by humans into the american continent. the first of them was the yellow fever virus, coming from the west african coast with slaves in the 17th-19th centuries, followed by dengue viruses, which were always prevalent within the americas. next was thewest nile virus, introduced in new york in 1999, that spread in only a few years over the whole continent. then, chikungunya virus arrived on saint martin island in 2013 after its ... | 2017 | 28509947 |
| whole-genome sequencing of drug-resistant salmonella enterica isolated from dairy cattle and humans in new york and washington states reveals source and geographic associations. | multidrug-resistant (mdr) salmonella enterica can be spread from cattle to humans through direct contact with animals shedding salmonella, as well as through the food chain, making mdr salmonella a serious threat to human health. the objective of this study was to use whole-genome sequencing to compare antimicrobial-resistant (amr) s. typhimurium, newport, and dublin isolated from dairy cattle and humans in washington state and new york state at a genotypic and phenotypic level. a total of 90 is ... | 2017 | 28389536 |
| filthy lucre: a metagenomic pilot study of microbes found on circulating currency in new york city. | paper currency by its very nature is frequently transferred from one person to another and represents an important medium for human contact with-and potential exchange of-microbes. in this pilot study, we swabbed circulating $1 bills obtained from a new york city bank in february (winter) and june (summer) 2013 and used shotgun metagenomic sequencing to profile the communities found on their surface. using basic culture conditions, we also tested whether viable microbes could be recovered from b ... | 2017 | 28384336 |
| quantifying the potential pathways and locations of rift valley fever virus entry into the united states. | the global invasion of west nile virus, chikungunya virus and zika virus in the past two decades suggests an increasing rate of mosquito-borne virus (arbovirus) dispersal. rift valley fever virus (rvfv) is an arbovirus identified as a high-consequence threat to the united states (usa) because of the severe economic and health consequences associated with disease. numerous studies demonstrate that the usa is receptive to rvfv transmission based on the widespread presence of competent mosquito spe ... | 2017 | 28191786 |
| development and validation of a climate-based ensemble prediction model for west nile virus infection rates in culex mosquitoes, suffolk county, new york. | west nile virus (wnv) is an endemic public health concern in the united states that produces periodic seasonal epidemics. underlying these outbreaks is the enzootic cycle of wnv between mosquito vectors and bird hosts. identifying the key environmental conditions that facilitate and accelerate this cycle can be used to inform effective vector control. | 2016 | 27507279 |
| population and evolutionary genomics of amblyomma americanum, an expanding arthropod disease vector. | the lone star tick, amblyomma americanum, is an important disease vector and the most frequent tick found attached to humans in the eastern united states. the lone star tick has recently experienced a rapid range expansion into the northeast and midwest, but despite this emerging infectious threat to wildlife, livestock, and human health, little is known about the genetic causes and consequences of the geographic expansion. in the first population genomic analysis of any tick species, we charact ... | 2016 | 27190204 |
| toxoplasma gondii and giardia duodenalis infections in domestic dogs in new york city public parks. | toxoplasma gondii and giardia duodenalis have been widely reported to produce major diseases in humans and domestic animals. little is known about the occurrence of these protozoan parasites in domestic dogs in the united states. the goal of this study was to determine the prevalence and genotypes of t. gondii and g. duodenalis among dogs in new york city. fecal samples from domestic dogs were analyzed by polymerase chain reaction (pcr). overall, 3% of the samples tested positive for t. gondii, ... | 2016 | 26988633 |
| benzothiazoles in indoor air from albany, new york, usa, and its implications for inhalation exposure. | benzothiazole and its derivatives (collectively referred to bths) are used widely in many consumer (e.g., textiles) and industrial (e.g., rubber) products. very little is known about the occurrence of bths in indoor air and the inhalation exposure of humans to these substances. in this study, 81 indoor air samples collected from various locations in albany, new york, usa, in 2014 were analyzed for bths by high-performance liquid chromatography-tandem mass spectrometry (hplc-ms/ms). bths were fou ... | 2016 | 26954474 |
| geography and timing of cases of eastern equine encephalitis in new york state from 1992 to 2012. | in new york state (nys), eastern equine encephalitis (eee) was first reported in a human in 1971, in horses in 1970, and in pheasants in 1952. | 2016 | 26901637 |
| preliminary survey of ectoparasites and associated pathogens from norway rats in new york city. | the norway rat (rattus norvegicus) is a reservoir of many zoonotic pathogens and lives in close proximity to humans in urban environments. human infection with rodent-borne disease occurs either directly through contact with a rat or its excreta, or indirectly via arthropod vectors such as fleas and ticks. here, we report on the diversity and abundance of ectoparasitic arthropod species and associated pathogenic bacteria from 133 norway rats trapped over a 10-mo period in manhattan, new york, ny ... | 2015 | 26336309 |
| occurrence of benzophenone-3 in indoor air from albany, new york, usa, and its implications for inhalation exposure. | benzophenone-3 (bp-3) is a widespread environmental contaminant and an estrogenic compound. very little is known with regard to the occurrence in indoor air and the inhalation exposure of humans to bp-3. in this study, 81 indoor air samples were collected from various locations in albany, new york, usa, in 2014 and analyzed for bp-3 by high performance liquid chromatography-tandem mass spectrometry (hplc-ms/ms). bp-3 was found in all indoor air samples and the overall concentrations in bulk air ... | 2015 | 26282764 |
| supersampling and network reconstruction of urban mobility. | understanding human mobility is of vital importance for urban planning, epidemiology, and many other fields that draw policies from the activities of humans in space. despite the recent availability of large-scale data sets of gps traces or mobile phone records capturing human mobility, typically only a subsample of the population of interest is represented, giving a possibly incomplete picture of the entire system under study. methods to reliably extract mobility information from such reduced d ... | 2015 | 26275237 |
| a real-time pcr assay for differentiating pathogenic anaplasma phagocytophilum from an apathogenic, woodrat-adapted genospecies from north america. | anaplasma phagocytophilum is a tick-transmitted bacterial pathogen of humans and animals comprising strains that cause clinical disease in people, dogs and horses (the pathogenic a. phagocytophilum "genospecies") and more distantly related strains. a rodent-adapted genospecies named du1, found primarily in woodrats, is unable to infect horses. we developed a real-time pcr (rt-pcr) assay, which targets an 85 base pair region of the ank gene and is specific for the pathogenic genospecies of a. pha ... | 2015 | 26188998 |
| variation in the microbiota of ixodes ticks with regard to geography, species, and sex. | ixodes scapularis is the principal vector of lyme disease on the east coast and in the upper midwest regions of the united states, yet the tick is also present in the southeast, where lyme disease is absent or rare. a closely related species, i. affinis, also carries the pathogen in the south but does not seem to transmit it to humans. in order to better understand the geographic diversity of the tick, we analyzed the microbiota of 104 adult i. scapularis and 13 adult i. affinis ticks captured i ... | 2015 | 26150449 |
| organobromine compound profiling in human adipose: assessment of sources of bromophenol. | bromophenols (brps) have been widely detected in human tissues, however, relative proportions from natural products and/or anthropogenic flame retardants are not clear. 21 polybrominated diphenyl ethers (pbdes), 15 meo/oh-pbdes, and 10 brps were simultaneously quantified in adipose collected from people from new york city, usa. an in vitro assay utilizing human liver microsomes was performed for detected predominant organobromine. high concentrations of 2,4,6-tribrp and pbdes were observed, and ... | 2015 | 25935608 |
| subtyping novel zoonotic pathogen cryptosporidium chipmunk genotype i. | cryptosporidium chipmunk genotype i is an emerging zoonotic pathogen in humans. the lack of subtyping tools makes it impossible to determine the role of zoonotic transmission in epidemiology. to identify potential subtyping markers, we sequenced the genome of a human chipmunk genotype i isolate. altogether, 9,509,783 bp of assembled sequences in 853 contigs were obtained, with an n50 of 117,886 bp and >200-fold coverage. based on the whole-genome sequence data, two genetic markers encoding the 6 ... | 2015 | 25762767 |
| accumulation of 19 environmental phenolic and xenobiotic heterocyclic aromatic compounds in human adipose tissue. | the extensive use of environmental phenols (e.g., bisphenol a) and heterocyclic aromatic compounds (e.g., benzothiazole) in consumer products as well as widespread exposure of humans to these compounds have been well documented. biomonitoring studies have used urinary measurements to assess exposures, based on the assumption that these chemicals are metabolized and eliminated in urine. despite the fact that some of these chemicals are moderately lipophilic, the extent of their accumulation in ad ... | 2015 | 25749637 |
| widespread occurrence and accumulation of bisphenol a diglycidyl ether (badge), bisphenol f diglycidyl ether (bfdge) and their derivatives in human blood and adipose fat. | despite the widespread use of bisphenol a diglycidyl ether (badge) and bisphenol f diglycidyl ether (bfdge) in various consumer products, studies on human exposure to these compounds are scarce. in this study, badge, bfdge, and seven of their derivatives were determined in human adipose fat and blood plasma samples collected from new york city, ny. bisphenol a bis (2,3-dihydroxypropyl) ether [badge·2h2o] was the major badge derivative found in 60% of the adipose samples and 70% of the plasma sam ... | 2015 | 25679329 |
| metal levels in eggs of waterbirds in the new york harbor (usa): trophic relationships and possible risk to human consumers. | health professionals are interested in evaluating the risks that heavy metals pose to eco-receptors and humans. the objective of this study was to examine levels of mercury (hg), lead (pb), cadmium (cd), and other contaminants in waterbirds nesting in the new york harbor in 2012 to determine (1) whether there were species and locational differences, and (2) whether consumption of eggs posed a health risk to predators or humans. for arsenic (as), pb, hg, and selenium (se), species contributed mor ... | 2015 | 25424617 |
| identifying common patterns in diverse systems: effects of exurban development on birds of the adirondack park and the greater yellowstone ecosystem, usa. | we examined the impacts of exurban development on bird communities in essex county, new york and madison county, montana by comparing differences in abundance of songbirds between subdivisions and control sites in both regions. we hypothesized that impacts to bird communities would be greater in the relatively homogeneous, closed canopy adirondack forest of northern new york state than they would be in the more naturally heterogeneous grasslands interspersed with trees and shrubs of the greater ... | 2015 | 25421994 |
| detection of zoonotic pathogens and characterization of novel viruses carried by commensal rattus norvegicus in new york city. | norway rats (rattus norvegicus) are globally distributed and concentrate in urban environments, where they live and feed in closer proximity to human populations than most other mammals. despite the potential role of rats as reservoirs of zoonotic diseases, the microbial diversity present in urban rat populations remains unexplored. in this study, we used targeted molecular assays to detect known bacterial, viral, and protozoan human pathogens and unbiased high-throughput sequencing to identify ... | 2014 | 25316698 |
| prevalence of borrelia miyamotoi in ixodes ticks in europe and the united states. | borrelia miyamotoi, a relapsing fever-related spirochete transmitted by ixodes ticks, has been recently shown to be a human pathogen. to characterize the prevalence of this organism in questing ixodes ticks, we tested 2,754 ticks for a variety of tickborne pathogens by pcr and electrospray-ionization mass spectrometry. ticks were collected from california, new york, connecticut, pennsylvania, and indiana in the united states and from germany and the czech republic in europe from 2008 through 201 ... | 2014 | 25280366 |
| dogs entering the united states from rabies-endemic countries, 2011-2012. | international dog imports pose a risk because of the potential movement of disease agents, including the canine rabies virus variant which has been eliminated from the united states since 2007. us regulations require a rabies vaccination certificate for dogs arriving from rabies-endemic countries, but permit the importation of dogs that have not been adequately immunized against rabies, provided that the dogs are confined under conditions that restrict their contact with humans and other animals ... | 2015 | 25244531 |
| six-year follow-up of a point-source exposure to cwd contaminated venison in an upstate new york community: risk behaviours and health outcomes 2005-2011. | it is currently unknown whether chronic wasting disease (cwd), a transmissible spongiform encephalopathy of cervids, is transmissible to humans. reported on here are the behavioural risk factors and health conditions associated with a six-year follow-up of a known point-source exposure to a cwd infected deer in an upstate new york community. | 2014 | 25225155 |
| jane cooke wright (1919-2013): pioneering oncologist, woman and humanitarian. | jane wright was a fundamental researcher in cancer chemotherapy in the 1950s-1980s and was one of the first scientists to test anti-cancer drugs on humans rather than solely on mice, discovering the use of the popular antimetabolite drug methotrexate on solid tumours. from her research she was able to conclude which specific anti-cancer agents would have the greatest lethal effect on a patient's certain cancer type and she invented a method of delivering chemotherapy agents directly to an intern ... | 2016 | 24585629 |
| prevalence of antibodies to toxoplasma gondii in white-tailed deer (odocoileus virginianus) in new york state, usa. | sera collected from 299 white-tailed deer (odocoileus virginianus) harvested in new york state by hunters in november 2010 were assayed for anti-toxoplasma gondii igg antibodies. white-tailed deer are a useful sentinel for risk of human and domestic animal exposure to toxoplasma oocysts and pose a potential risk for infection to humans and other animals by ingestion of the meat. white-tailed deer share grazing space with domestic animals raised for meat and are likely to be exposed by horizontal ... | 2013 | 24502721 |
| twenty-year summary of surveillance for human hantavirus infections, united states. | in the past 20 years of surveillance for hantavirus in humans in the united states, 624 cases of hantavirus pulmonary syndrome (hps) have been reported, 96% of which occurred in states west of the mississippi river. most hantavirus infections are caused by sin nombre virus, but cases of hps caused by bayou, black creek canal, monongahela, and new york viruses have been reported, and cases of domestically acquired hemorrhagic fever and renal syndrome caused by seoul virus have also occurred. rare ... | 2013 | 24274585 |
| forest fragmentation and risk of giardiasis in new york state. | in the united states, giardiasis is endemic in northern and northeastern states, but its ecology and epidemiology remain elusive. the underlying physical landscape may play a role in shaping points of contact between humans, animals, and giardia cysts. this study examined 11 years of surveillance data in new york state to measure the relationship between forest fragmentation and the incidence of giardiasis. adjusted poisson models showed that increasing points of contact between forested land an ... | 2013 | 24142462 |
| host specificity and source of enterocytozoon bieneusi genotypes in a drinking source watershed. | to assess the host specificity of enterocytozoon bieneusi and to track the sources of e. bieneusi contamination, we genotyped e. bieneusi in wildlife and stormwater from the watershed of new york city's source water, using ribosomal internal transcribed spacer (its)-based pcr and sequence analyses. a total of 255 specimens from 23 species of wild mammals and 67 samples from stormwater were analyzed. seventy-four (29.0%) of the wildlife specimens and 39 (58.2%) of the stormwater samples from stre ... | 2014 | 24141128 |
| the effect of polychlorinated biphenyls on the song of two passerine species. | polychlorinated biphenyls (pcbs) are synthetic chemical pollutants with demonstrated detrimental toxic and developmental effects on humans and wildlife. laboratory studies suggest that pcbs influence behavior due to their effects on endocrine and neurological systems, yet little is known about the behavioral consequences of sublethal pcb exposure in the field. additionally, specific pcb congener data (in contrast to total pcb load) is necessary to understand the possible effects of pcbs in livin ... | 2013 | 24058475 |
| aedes (stegomyia) aegypti in the continental united states: a vector at the cool margin of its geographic range. | after more than a half century without recognized local dengue outbreaks in the continental united states, there were recent outbreaks of autochthonous dengue in the southern parts of texas (2004-2005) and florida (2009-2011). this dengue reemergence has provoked interest in the extent of the future threat posed by the yellow fever mosquito, aedes (stegomyia) aegypti (l.), the primary vector of dengue and yellow fever viruses in urban settings, to human health in the continental united states. a ... | 2013 | 23802440 |
| occurrence of and dietary exposure to parabens in foodstuffs from the united states. | parabens are esters of p-hydroxybenzoic acid and are widely used as preservatives in cosmetics, pharmaceuticals, foodstuffs, including beverages. information on the occurrence of parabens in foodstuffs and dietary exposure of humans to these chemicals is not available. in this study, food samples (n = 267) collected from albany, new york, united states, were grouped into eight categories, namely, beverages, dairy products, fats and oils, fish and shellfish, grains, meat, fruits, and vegetables, ... | 2013 | 23506043 |
| the relevance of forest fragmentation on the incidence of human babesiosis: investigating the landscape epidemiology of an emerging tick-borne disease. | babesiosis is an emerging arthropod-borne infection that has been increasing in incidence for the last decade in the northeastern united states. babesiosis may share features of its landscape epidemiology with other arthropod-borne infections transmitted by the same tick vectors in similar geographic spaces. this study examined 11 years of surveillance data in new york state to measure the relationship between forest fragmentation and the incidence of human babesiosis. adjusted poisson models sh ... | 2013 | 23428092 |
| disease risk surface for coxiella burnetii seroprevalence in white-tailed deer. | coxiella burnetii is considered a re-emerging zoonosis in many countries. the bacterium is enzootic in livestock and wildlife in the united states, and environmental contamination is widespread. despite the potential for exposure, the estimated prevalence of q fever in humans and animals is not well elucidated, and reported human infections in the united states are relatively rare. zoonotic transmission of the bacterium is usually associated with abortions in domestic ruminants, but other modes ... | 2013 | 23176671 |
| farm animal contact as risk factor for transmission of bovine-associated salmonella subtypes. | salmonellosis is usually associated with foodborne transmission. to identify risk from animal contact, we compared animal exposures of case-patients infected with bovine-associated salmonella subtypes with those of control-patients infected with non-bovine-associated subtypes. we used data collected in new york and washington, usa, from march 1, 2008, through march 1, 2010. contact with farm animals during the 5 days before illness onset was significantly associated with being a case-patient (od ... | 2012 | 23171627 |
| analysis of the 3'-variable region of the caga gene from helicobacter pylori strains infecting patients at new york city hospitals. | helicobacter pylori infects the gastric mucosa in humans and is a causative agent for peptic ulcer disease (pud) and gastric cancer (gc). caga is produced by h. pylori and is associated with more severe outcomes. caga genes vary at the 3'-region with respect to phosphorylation motifs (epiya-a, -b, -c, or -d) and caga multimerization motifs (cm). this variability may be associated with the clinical outcomes. we examined the variable region of caga genes expressed in h. pylori-infected patients tr ... | 2013 | 23117095 |
| evaluation of a neighborhood rat-management program--new york city, december 2007-august 2009. | the norway rat (rattus norvegicus) is a pervasive urban rodent that can carry a variety of pathogens transmissible to humans, bring stress to residents of infested neighborhoods, damage property, and cause financial loss. several areas of new york city have experienced persistent rat infestation despite a longstanding rat control program that employed property-level inspection and control measures triggered by individual citizen complaints, a common approach in urban areas. recognizing the need ... | 2012 | 22992570 |
| producer survey of bird-livestock interactions in commercial dairies. | the objective of this producer survey was to identify and estimate damage caused by bird-livestock interactions in commercial dairies. the interactions between birds and livestock have previously been implicated in causing economic damage while contributing to the environmental dissemination of microorganisms pathogenic to livestock and humans. very little research exists to help producers understand what bird species use dairies, why they use dairies, or the scope and nature of damage created a ... | 2012 | 22981584 |
| rabies surveillance in the united states during 2011. | during 2011, 49 states and puerto rico reported 6,031 rabid animals and 6 human rabies cases to the cdc, representing a 1.9% decrease from the 6,153 rabid animals and 2 human cases reported in 2010. approximately 92% of reported rabid animals were wildlife. relative contributions by the major animal groups were as follows: 1,981 raccoons (32.8%), 1,627 skunks (27.0%), 1,380 bats (22.9%), 427 foxes (7.1%), 303 cats (5.0%), 65 cattle (1.1%), and 70 dogs (1.2%). compared with 2010, there was a subs ... | 2012 | 22947154 |
| dogs and horses with antibodies to outer-surface protein c as on-time sentinels for ticks infected with borrelia burgdorferi in new york state in 2011. | reported cases of lyme disease (a chronic disease caused by infection with borrelia burgdorferi) in humans increased more than two-fold between 1992 and 2006 in the united states. recently, the annual number of reported human lyme disease cases stabilized (according to the center for disease control and prevention) but the geographic distribution seemed to increase. in new york (ny) state, usa, a spread from the original lyme disease focus in southeastern parts of the state has occurred. we dete ... | 2012 | 22841496 |
| a temperature-limited assessment of the risk of rift valley fever transmission and establishment in the continental united states of america. | the rapid spread of west nile virus across north america after its introduction in 1999 highlights the potential for foreign arboviruses to become established in the united states of america. of particular concern is rift valley fever virus (rvfv), which has been responsible for multiple african epidemics resulting in death of both humans and livestock, as well as major economic disruption due to livestock loss and trade restrictions. modern globalization, travel, and commerce allow viruses to e ... | 2012 | 22639118 |
| enhanced mammalian transmissibility of seasonal influenza a/h1n1 viruses encoding an oseltamivir-resistant neuraminidase. | between 2007 and 2009, oseltamivir resistance developed among seasonal influenza a/h1n1 (sh1n1) virus isolates at an exponential rate, without a corresponding increase in oseltamivir usage. we hypothesized that the oseltamivir-resistant neuraminidase (na), in addition to being relatively insusceptible to the antiviral effect of oseltamivir, might confer an additional fitness advantage on these viruses by enhancing their transmission efficiency among humans. here we demonstrate that an oseltamivi ... | 2012 | 22532693 |
| infectious disease survey of mus musculus from pet stores in new york city. | most mice used in research are purchased devoid of specific pathogens. experimental studies required us to evaluate the profile of infective agents harbored in mice sold as pets or food for captive reptiles. anecdotal reports regarding disease in these mice abound, but there are few published reports on disease prevalence. purchasers are unaware of the potential zoonotic or adventitious infections carried by these mice. this survey investigated the prevalence of ectoparasites, endoparasites, and ... | 2012 | 22330866 |
| missing from the table: role of the environmental public health community in governmental advisory commissions related to marcellus shale drilling. | background: the marcellus shale is a vast natural gas field underlying parts of pennsylvania, new york, west virginia, virginia and maryland. rapid development of this field has been enabled by advances in hydrofracking techniques that include injection of chemical and physical agents deep underground. response to public concern about potential adverse environmental and health impacts has led to the formation of state and national advisory committees. objectives: we review the extent to whic ... | 2012 | 22233770 |
| inotropic contractile reserve can risk-stratify patients with hiv cardiomyopathy: a dobutamine stress echocardiography study. | the purpose of this study was to assess whether inotropic contractile reserve (icr) during dobutamine stress echocardiography (dse) could risk-stratify patients with human immunodeficiency virus (hiv) cardiomyopathy and predict improvement of left ventricular ejection fraction (lvef). | 2011 | 22172778 |
| bat rabies and human postexposure prophylaxis, new york, usa. | 2011 | 22172493 | |
| first reports of human rotavirus g8p[4] gastroenteritis in the united states. | in 2009, three children were hospitalized in rochester, ny with sequence-confirmed g8p[4] rotavirus gastroenteritis-the first us detection of this uncommon strain more typically found in africa. continued monitoring of g8p[4] and other rotavirus genotypes not represented in current vaccines is essential to assess whether vaccination will result in an increase in prevalence of these strains. | 2011 | 22170918 |
| Temporal variability in urinary concentrations of perchlorate, nitrate, thiocyanate and iodide among children. | Perchlorate, nitrate and thiocyanate are ubiquitous in the environment, and human exposure to these chemicals is accurately measured in urine. Biomarkers of these chemicals represent a person's recent exposure, however, little is known on the temporal variability of the use of a single measurement of these biomarkers. Healthy Hispanic and Black children (6-10-year-old) donated urine samples over 6 months. To assess temporal variability, we used three statistical methods (n=29; 153 urine samples) ... | 2011 | 22166811 |
| a randomized trial of a behavioral intervention for black men who have sex with men: the dish study. | objective:: to test a new behavioral intervention for black men who have sex with men in reducing sexual risk and increasing social support and intentions to use condoms. design:: a single site, unblinded randomized trial in new york city with 3-month follow-up. methods:: participants (nā=ā283) reporting at least 2 sexual partners and unprotected anal intercourse with a man in the past 3 months were enrolled and randomized to a social-cognitive theory based intervention or control comparison. me ... | 2011 | 22156967 |
| modeling spatial variations of black carbon particles in an urban highway-building environment. | highway-building environments are prevalent in metropolitan areas. this paper presents our findings in investigating pollutant transport in a highway-building environment by combing field measurement and numerical simulations. we employ and improve the comprehensive turbulent aerosol dynamics and gas chemistry (ctag) model to simulate the spatial variations of black carbon (bc) concentrations near highway i-87 and an urban school in the south bronx, new york. the results of ctag simulations are ... | 2011 | 22084971 |
| temporally structured metapopulation dynamics and persistence of influenza a h3n2 virus in humans. | populations of seasonal influenza virus experience strong annual bottlenecks that pose a considerable extinction risk. it has been suggested that an influenza source population located in tropical southeast or east asia seeds annual temperate epidemics. here we investigate the seasonal dynamics and migration patterns of influenza a h3n2 virus by analysis of virus samples obtained from 2003 to 2006 from australia, europe, japan, new york, new zealand, southeast asia, and newly sequenced viruses f ... | 2011 | 22084096 |
| a community mobilizes to end medical apartheid. | problem: people of color suffer worse health outcomes than their white counterparts due, in part, to limited access to high-quality specialty care. purpose: this article describes the events that led to the bronx health reach coalition's decision to file a civil rights complaint with the new york state office of the attorney general alleging that three academic medical centers in new york city discriminated on the basis of payer status and race in violation of title vi of the civil rights ... | 2011 | 22080781 |
| pneumothorax in a young man in brooklyn, new york. | 2011 | 22080120 | |
| polybrominated diphenyl ethers (pbdes), polychlorinated biphenyls (pcbs) and neuropsychological status among older adults in new york. | polybrominated diphenyl ethers (pbdes) are emerging environmental contaminants, but little is known about their possible human health effects. the objective of this study is to evaluate the association between exposure to pbdes and neuropsychological function among older adults and the possibility of effect modification with polychlorinated biphenyls (pcbs). serum samples were analyzed for concentrations of 9 pbde and 30 pcb congeners and 34 tests of cognitive and motor function, affective state ... | 2011 | 22079442 |
| Evaluating the combined effectiveness of influenza control strategies and human preventive behavior. | Control strategies enforced by health agencies are a major type of practice to contain influenza outbreaks. Another type of practice is the voluntary preventive behavior of individuals, such as receiving vaccination, taking antiviral drugs, and wearing face masks. These two types of practices take effects concurrently in influenza containment, but little attention has been paid to their combined effectiveness. This article estimates this combined effectiveness using established simulation models ... | 2011 | 22043275 |
| Fish consumption, low-level mercury, lipids, and inflammatory markers in children. | There is considerable evidence that consuming fish has numerous health benefits, including a reduced risk of cardiovascular disease. However, fish is also the primary source of human exposure to mercury (Hg). In a cross-sectional study of 9-11 year old children (N=100), we measured fish consumption, blood lipids, total blood Hg, diurnal salivary cortisol (4 samples collected throughout the day), and performed a proteomic analysis of serum proteins using spectral count shotgun proteomics. Childre ... | 2011 | 22030286 |
| molecular detection of viral causes of encephalitis and meningitis in new york state. | the etiology of encephalitis and meningitis, serious diseases of the central nervous system (cns), in most cases remains unknown. the importance of establishing a diagnosis however, becomes even more important as advances are made in effective therapy. molecular methods of detection, in particular, pcr, are being used routinely and have established a place in the arsenal of tools for diagnosis of cns infections. in this study a viral etiological agent was detected by pcr in 340 of the total 2,35 ... | 2011 | 22012726 |
| stem cells. where do human eggs come from? | 2011 | 21980085 | |
| The impact of missed opportunities on seasonal influenza vaccination coverage for healthy young children. | To estimate the impact of missed opportunities on influenza vaccination coverage among 6- through 23-month-old children who sought medical care during the 2004-2005 influenza season. | 2011 | 21964369 |
| acute illnesses associated with insecticides used to control bed bugs--seven states, 2003--2010. | the common bed bug, cimex lectularius, is a wingless, reddish-brown insect that requires blood meals from humans, other mammals, or birds to survive. bed bugs are not considered to be disease vectors, but they can reduce quality of life by causing anxiety, discomfort, and sleeplessness. bed bug populations and infestations are increasing in the united states and internationally. bed bug infestations often are treated with insecticides, but insecticide resistance is a problem, and excessive use o ... | 2011 | 21937972 |
| comparison of health outcomes among affiliated and lay disaster volunteers enrolled in the world trade center health registry. | volunteers (non-professional rescue/recovery workers) are universally present at man-made and natural disasters and share experiences and exposures with victims. little is known of their disaster-related health outcomes. | 2011 | 21930152 |
| Serum and follicular fluid ghrelin levels negatively reflect human oocyte quality and in vitro embryo development. | To characterize serum and follicular fluid (FF) ghrelin in women undergoing assisted reproduction and to evaluate ghrelin's impact on ovarian steroidogenesis, oocyte quality, and embryo development. | 2011 | 21924713 |
| Promoter methylation of E-cadherin, p16, and RAR-ß(2) genes in breast tumors and dietary intake of nutrients important in one-carbon metabolism. | Aberrant DNA methylation plays a critical role in carcinogenesis, and the availability of dietary factors involved in 1-carbon metabolism may contribute to aberrant DNA methylation. We investigated the association of intake of folate, vitamins B(2), B(6), B(12), and methionine with promoter methylation of E-cadherin, p16, and RAR-ß(2) genes in archived tumor tissues from incident, primary breast cancer cases in a population-based case-control study. Real-time methylation-specific PCR was perform ... | 2011 | 21916701 |
| agents of human anaplasmosis and lyme disease at camp ripley, minnesota. | the transmission dynamics of anaplasma phagocytophilum (ap) and borrelia burgdorferi (bb) among ixodes scapularis (is) and mammalian hosts was investigated at camp ripley, an area representative of central minnesota. prevalence of white-footed mouse infection with ap and bb were 20% and 42%, respectively, with a coinfection level of 14%. peak levels of infection with both agents occurred in may. the average levels of seropositivity to ap and bb were 29.3% and 48%, respectively. of the mice infec ... | 2011 | 21867420 |
| The Rockefeller University Hospital (1910-2010): creating the science of medicine. | The year 2010 marked the centennial of the Rockefeller University Hospital, one of the great philanthropic achievements of 20th-century science. For 100 years, the Hospital played a central role in the development and growth of medical science by enabling physician-scientists to make intensive study of human biology and disease. With ingenuity and devotion, they greatly enriched clinical medicine as well as basic biological science. This account emphasizes the founding and first half-century of ... | 2011 | 21857122 |
| predictive mapping of human risk for west nile virus (wnv) based on environmental and socioeconomic factors. | a west nile virus (wnv) human risk map was developed for suffolk county, new york utilizing a case-control approach to explore the association between the risk of vector-borne wnv and habitat, landscape, virus activity, and socioeconomic variables derived from publically available datasets. results of logistic regression modeling for the time period between 2000 and 2004 revealed that higher proportion of population with college education, increased habitat fragmentation, and proximity to wnv po ... | 2011 | 21853103 |
| fate of perchlorate in a man-made reflecting pond following a fireworks display in albany, new york, usa. | perchlorate is a widespread contaminant in aquatic environments. despite this, the aquatic environmental fate of perchlorate released from fireworks displays is not well known. in the present study, we examined the fate of perchlorate in man-made reflecting ponds, from 2008 to 2010, following three fireworks displays in albany, new york, usa. immediately after the fireworks display, perchlorate in pond waters increased significantly, with concentrations from 30 to 1,480 times higher than the bas ... | 2011 | 21850663 |
| Molting success of Ixodes scapularis varies among individual blood meal hosts and species. | The blacklegged tick (Ixodes scapularis) is an important vector of emerging human pathogens. It has three blood-feeding stages, as follows: larva, nymph, and adult. Owing to inefficient transovarial transmission, at least for the Lyme disease agent (Borrelia burgdorferi), larval ticks rarely hatch infected, but they can acquire infection during their larval blood meal. Nymphal ticks are primarily responsible for transmitting pathogens to hosts, including humans. The transition from uninfected ho ... | 2011 | 21845946 |
| barriers to hiv testing among hiv/aids concurrently diagnosed persons in new york city. | : to assess barriers to human immunodeficiency virus (hiv) testing, health care contacts history, and hiv testing history among patients diagnosed concurrently with hiv and acquired immunodeficiency syndrome (aids). | 2011 | 21844723 |
| decelerating spread of west nile virus by percolation in a heterogeneous urban landscape. | vector-borne diseases are emerging and re-emerging in urban environments throughout the world, presenting an increasing challenge to human health and a major obstacle to development. currently, more than half of the global population is concentrated in urban environments, which are highly heterogeneous in the extent, degree, and distribution of environmental modifications. because the prevalence of vector-borne pathogens is so closely coupled to the ecologies of vector and host species, this het ... | 2011 | 21829332 |
| soul whisperers. | personal recollections are offered in reflection upon the tragedy of 9/11. the outreach efforts of the blanton-peale institute in conjunction with the health care chaplaincy of new york and the red cross are recalled by ceo emeritus, kathryn madden. a brief clinical study describes the responses of a young man who was one of only a few persons to make it out of the north tower from above the 85th floor. blanton-peale's benefit honorees brian clark, lauren and greg manning are named as survivors ... | 2011 | 21826557 |
| human health risk assessment of synthetic turf fields based upon investigation of five fields in connecticut. | questions have been raised regarding possible exposures when playing sports on synthetic turf fields cushioned with crumb rubber. rubber is a complex mixture with some components possessing toxic and carcinogenic properties. exposure is possible via inhalation, given that chemicals emitted from rubber might end up in the breathing zone of players and these players have high ventilation rates. previous studies provide useful data but are limited with respect to the variety of fields and scenarios ... | 2011 | 21797769 |
| hiv-2 infection surveillance --- united states, 1987--2009. | human immunodeficiency virus (hiv) is categorized into two types, hiv-1 and hiv-2. worldwide, most hiv infections are hiv-1, whereas hiv-2 largely has been confined to persons in or from west africa. hiv-1 and hiv-2 have the same routes of transmission, and both can cause acquired immunodeficiency syndrome (aids); however, hiv-2 infections should be differentiated from hiv-1 infections because they are less likely to cause aids and their clinical management differs. cdc's current surveillance ca ... | 2011 | 21796096 |
| sexual transmission of hepatitis c virus among hiv-infected men who have sex with men --- new york city, 2005--2010. | in the united states, an estimated 3.2 million persons are living with hepatitis c virus (hcv) infection. hcv transmission occurs primarily through percutaneous exposure to blood, and persons who inject drugs are at greatest risk for infection. the role of sexual transmission of hcv has not been well defined. however, reports over the past decade, mainly from europe, have implicated sexual transmission of hcv among human immunodeficiency virus (hiv)--infected men who have sex with men (msm). in ... | 2011 | 21775948 |
| exposure to lymphocytic choriomeningitis virus, new york, usa. | to the editor: lymphocytic choriomeningitis virus (lcmv) is an arenavirus carried by the house mouse, mus musculus. human infections can range from mild febrile illness to severe encephalitis and disseminated disease (1). infection during pregnancy is associated with teratogenic effects, including congenital hydrocephalus and chorioretinitis (2). | 2011 | 21762607 |
| the ultimate benefit to be derived from the epidemic. | 2011 | 21750280 | |
| interview: commercial translation of cell-based therapies and regenerative medicine: learning by experience. | dr haseltine speaks to emily culme-seymour, assistant commissioning editor william a haseltine, phd has an active career in both science and business. he was a professor at harvard medical school and harvard school of public health (ma, usa) from 1976 to 1993, where he was founder and chair of two academic research departments. he is well known for his pioneering work on cancer, hiv/aids and genomics. he has authored more than 200 manuscripts in peer-reviewed journals and is the author of severa ... | 2011 | 21749201 |
| distributions of polyhalogenated compounds in hudson river (new york, usa) fish in relation to human uses along the river. | pcbs (as aroclor concentrations) have been extensively examined in fish along the hudson river, but other xenobiotic chemicals in fish have had limited assessment. this study determined concentrations and congener distributions of polybrominated diphenyl ethers (pbdes), polybrominated and polychlorinated dibenzo-p-dioxins and dibenzofurans (pbdd/fs and pcdd/fs), and polychlorinated biphenyls (pcbs) in smallmouth bass and striped bass taken from a 385km reach of the hudson river. concentrations o ... | 2011 | 21742424 |
| agent-based simulation for weekend-extension strategies to mitigate influenza outbreaks. | abstract: | 2011 | 21718518 |
| association of rad51 polymorphism with dna repair in brca1 mutation carriers and sporadic breast cancer risk. | abstract: | 2011 | 21708019 |
| exome sequencing identified myo1e and neil1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome. | to identify gene loci associated with steroid-resistant nephrotic syndrome (srns), we utilized homozygosity mapping and exome sequencing in a consanguineous pedigree with three affected siblings. high-density genotyping identified three segments of homozygosity spanning 33.6ôçëmb on chromosomes 5, 10, and 15 containing 296 candidate genes. exome sequencing identified two homozygous missense variants within the chromosome 15 segment; an a159p substitution in myosin 1e (myo1e), encoding a podocyte ... | 2011 | 21697813 |
| a survival analysis approach to modeling human fecundity. | understanding conception probabilities is important not only for helping couples to achieve pregnancy but also in identifying acute or chronic reproductive toxicants that affect the highly timed and interrelated processes underlying hormonal profiles, ovulation, libido, and conception during menstrual cycles. currently, 2 statistical approaches are available for estimating conception probabilities depending upon the research question and extent of data collection during the menstrual cycle: a su ... | 2011 | 21697247 |
| predictors of acceptance of h1n1 influenza vaccination by fdny firefighters and ems workers. | there is a widely recognized need for vaccination of health care workers (hcws). we undertook this study to assess the 2009-2010 h1n1 vaccination rates in ôê+14,000 firefighters and emergency medical service (ems) workers at the fire department of new york (fdny) and to determine predictors of h1n1 vaccine acceptance. | 2011 | 21693157 |
| spatial patterns of mercury in biota of adirondack, new york lakes. | we studied the spatial distribution patterns of mercury (hg) in lake water, littoral sediments, zooplankton, crayfish, fish, and common loons in 44 lakes of the adirondacks of new york state, usa, a region that has been characterized as a "biological hg hotspot". our study confirmed this pattern, finding that a substantial fraction of the lakes studied had fish and loon samples exceeding established criteria for human and wildlife health. factors accounting for the spatial variability of hg in l ... | 2011 | 21691858 |
| lead, mercury, cadmium, chromium, and arsenic levels in eggs, feathers, and tissues of canada geese of the new jersey meadowlands. | the new jersey meadowlands are located within the heavily urbanized new york/new jersey harbor estuary and have been subject to contamination due to effluent and runoff from industry, traffic, and homes along the hackensack river and nearby waterways. these extensive wetlands, though heavily impacted by development and pollution, support a wide array of bird and other wildlife species. persistent contaminants may pose threats to birds in these habitats, affecting reproduction, egg hatchability, ... | 2011 | 21679937 |
| heat shock factor y chromosome (hsfy) mrna level predicts the presence of retrievable testicular sperm in men with nonobstructive azoospermia. | to evaluate heat shock factor y chromosome (hsfy) mrna as a biomarker for the presence of retrievable testicular sperm. | 2011 | 21676392 |
| 'it was a freak accident': an analysis of the labelling of injury events in the us press. | objectives given that the news media shape our understanding of health issues, a study was undertaken to examine the use by the us media of the expression 'freak accident' in relation to injury events. this analysis is intended to contribute to the ongoing consideration of lay conceptualisation of injuries as 'accidents'. methods lexisnexis academic was used to search three purposively selected us news sources (associated press, new york times and philadelphia inquirer) for the expression 'freak ... | 2011 | 21659441 |
| sunitinib in urothelial cancer: clinical, pharmacokinetic, and immunohistochemical study of predictors of response. | background: sunitinib has activity in patients with metastatic urothelial cancer (uc), but most patients do not respond. objective: to identify predictors of response to sunitinib. design, setting, and participants: seventy-seven patients with advanced uc received sunitinib on one of two schedules at a single institution. blood pressure (bp), immunohistochemistry (ihc), and pharmacokinetic (pk) results were correlated with response to sunitinib. measurements: bp was assessed on day 1 and 28 of e ... | 2011 | 21645967 |
| single nucleotide polymorphisms in dna repair genes and association with breast cancer risk in the web study. | base excision and nucleotide excision repair pathways repair damaged dna, and polymorphisms in these genes might affect breast cancer susceptibility. we evaluated associations between 7 single nucleotide polymorphisms (snps) in 4 dna repair genes (ercc4 rs1799801, xpc rs2227998, rs2228001, rs2228000, ogg1 rs1052133, and xrcc1 rs25487 and rs25486) and breast cancer risk, examining modification by smoking and alcohol consumption, using data from the western new york exposures and breast cancer (we ... | 2011 | 21622940 |
| pik3ca mutations rarely demonstrate genotypic intratumoral heterogeneity and are selected for in breast cancer progression. | pik3ca gene mutations are the most common activating mutations in human breast cancer. its association with hormone receptor-positive breast cancer makes it a prime target for clinical therapeutic advances to maintain anti-estrogen responsiveness. in anticipation of this therapeutic approach, we have evaluated intratumoral heterogeneity in primary breast cancers with regard to pik3ca mutation status. in addition, we have assessed for the presence of the mutation in paired pre-invasive breast can ... | 2011 | 21617917 |
| testing. claims by man who falsely thought he had hiv may proceed. | 2011 | 21585003 | |
| associations between herpes simplex virus type 2 and hcv with hiv among injecting drug users in new york city. | objectives. we examined relationships between herpes simplex virus type 2 (hsv-2), a biomarker for sexual risk, and hcv, a biomarker for injecting risk, with hiv among injecting drug users (idus) who began injecting after large-scale expansion of syringe exchange programs in new york city. methods. we recruited 337 heroin and cocaine users who began injecting in 1995 or later from persons entering drug detoxification. we administered a structured interview covering drug use and hiv risk behavior ... | 2011 | 21566021 |
| an innovative approach to interdisciplinary occupational safety and health education. | the new york and new jersey education and research center (erc) provides a range of graduate continuing education for occupational safety and health (osh) professionals in training. a key element of the education is to provide interdisciplinary training to industrial hygienists, ergonomists, occupational medicine physicians and other health and safety trainees to prepare them for the collaboration required to solve the complex occupational health and safety problems they will face in their caree ... | 2011 | 21557281 |
| elevated body mass index is associated with lower serum anti-mullerian hormone levels in infertile women with diminished ovarian reserve but not with normal ovarian reserve. | to investigate the association between elevated body mass index (bmi) and ovarian reserve. | 2011 | 21529798 |
| intervention to influence behaviors linked to risk of chronic diseases: a multisite randomized controlled trial with african-american hiv-serodiscordant heterosexual couples. | background: the high morbidity and mortality in african americans associated with behavior-linked chronic diseases are well documented. methods: we tested the efficacy of an intervention to increase multiple health-related behaviors in african americans. in a multisite cluster-randomized controlled trial, groups of african american human immunodeficiency virus (hiv)-serodiscordant heterosexual couples in atlanta (georgia), los angeles (california), new york (new york), and philadelphia (pennsylv ... | 2011 | 21518939 |
| random anti-müllerian hormone (amh) is a predictor of ovarian response in women with elevated baseline early follicular follicle-stimulating hormone levels. | to investigate the utility of random anti-müllerian hormone (amh) in assessing ovarian response among women with diminished ovarian reserve (dor) diagnosed by elevated early follicular-phase fsh levels. | 2011 | 21497340 |