Publications

helicobacter cetorum sp. nov., a urease-positive helicobacter species isolated from dolphins and whales.	a novel helicobacter with the proposed name helicobacter cetorum, sp. nov. (type strain mit 99-5656; genbank accession number af 292378), was cultured from the main stomach of two wild, stranded atlantic white-sided dolphins (lagenorhynchus acutus) and from the feces of three captive cetaceans (a pacific white-sided dolphin [lagenorhynchus obliquidens]; an atlantic bottlenose dolphin [tursiops truncatus]; and a beluga whale [delphinapterus leucas]). the infected captive cetaceans were either sub ...	2002	12454148
comparison of diagnostic techniques for helicobacter cetorum infection in wild atlantic bottlenose dolphins (tursiops truncatus).	helicobacter cetorum sp. nov. has been cultured from the stomach of atlantic white-sided dolphins (lagenorhynchus acutus) and the feces of pacific white-sided (l. obliquidens) and atlantic bottlenose (tursiops truncatus) dolphins and a beluga whale (delphinapterus leucas). h. cetorum has high homology to helicobacter pylori as shown by 16s rrna sequencing, and h. cetorum infection has been associated with gastritis and clinical signs in cetaceans. because the prevalence of h. cetorum in wild pop ...	2003	12843010
isolation and characterization of novel helicobacter spp. from the gastric mucosa of harp seals phoca groenlandica.	since the recent discovery of helicobacter cetorum in cetaceans and its role in the development of gastritis, speculation has existed as to whether pinnipeds have helicobacter spp. associated gastritis and peptic ulcer disease. the gastric mucosa of 4 stranded harp seals phoca groenlandica from the massachusetts coastline were assessed for helicobacter spp. by culture and pcr. we cultured 2 novel helicobacter spp. from the pyloric antrum of 1 of the 4 harp seals studied, and identified these by ...	2003	14735915
non-pylori helicobacteraceae in the upper digestive tract of asymptomatic venezuelan subjects: detection of helicobacter cetorum-like and candidatus wolinella africanus-like dna.	the spectrum of human non-pylori helicobacter infections is expanding, with species such as h. heilmannii and h. felis occasionally being associated with gastritis. however, the existence of non-pylori helicobacter colonization in asymptomatic subjects has not been evaluated. the aim of this study was to investigate whether helicobacter species other than pylori are present in the upper digestive tract of asymptomatic human subjects.	2007	17760725
detection of helicobacter in the digestive tract of an atlantic spotted dolphin (stenella frontalis).	helicobacter spp. occur in the digestive system of a broad range of animal taxa, including marine mammals. only one formally recognized species, helicobacter cetorum, has been described in marine mammals. helicobacter has not been reported in the atlantic spotted dolphin (stenella frontalis). the purpose of our study was to examine the digestive tract of a stranded spotted dolphin for helicobacter. tissue and content samples were collected at necropsy and examined by histopathology and molecular ...	2010	20688662
nodeomics: pathogen detection in vertebrate lymph nodes using meta-transcriptomics.	the ongoing emergence of human infections originating from wildlife highlights the need for better knowledge of the microbial community in wildlife species where traditional diagnostic approaches are limited. here we evaluate the microbial biota in healthy mule deer (odocoileus hemionus) by analyses of lymph node meta-transcriptomes. cdna libraries from five individuals and two pools of samples were prepared from retropharyngeal lymph node rna enriched for polyadenylated rna and sequenced using ...	2010	20976145
sequence divergence and conservation in genomes of helicobacter cetorum strains from a dolphin and a whale.	strains of helicobacter cetorum have been cultured from several marine mammals and have been found to be closely related in 16 s rdna sequence to the human gastric pathogen h. pylori, but their genomes were not characterized further.	2013	24358262
comparative analysis of the full genome of helicobacter pylori isolate sahul64 identifies genes of high divergence.	isolates of helicobacter pylori can be classified phylogeographically. high genetic diversity and rapid microevolution are a hallmark of h. pylori genomes, a phenomenon that is proposed to play a functional role in persistence and colonization of diverse human populations. to provide further genomic evidence in the lineage of h. pylori and to further characterize diverse strains of this pathogen in different human populations, we report the finished genome sequence of sahul64, an h. pylori strai ...	2014	24375107
helicobacter cetorum infection in striped dolphin (stenella coeruleoalba), atlantic white-sided dolphin (lagenorhynchus acutus), and short-beaked common dolphin (delphinus delphus) from the southwest coast of england.	helicobacter infection in cetaceans was first reported from the us in 2000 when the isolation of a novel helicobacter species was described from two atlantic white-sided dolphins (lagenorhynchus acutus). since then, helicobacter species have been demonstrated in cetaceans and pinnipeds from around the world. since 1990, the animal health and veterinary laboratories agency polwhele, truro, has been involved in the uk cetacean strandings investigation programme to establish the cause of death of c ...	2014	24807181
transmission of the pabi family of restriction dna glycosylase genes: mobility and long-term inheritance.	r.pabi is an exceptional restriction enzyme that functions as a dna glycosylase. the enzyme excises an unmethylated base from its recognition sequence to generate apurinic/apyrimidinic (ap) sites, and also displays ap lyase activity, cleaving the dna backbone at the ap site to generate the 3'-phospho alpha, beta-unsaturated aldehyde end in addition to the 5'-phosphate end. the resulting ends are difficult to religate with dna ligase. the enzyme was originally isolated in pyrococcus, a hypertherm ...	2015	26481899