Publications

patulin production by byssochlamys spp. in fruit juices.	ten strains of byssochlamys fulva and three strains of b. nivea were cultured in a laboratory medium and tested for their ability to produce patulin. two strains of b. fulva and all three strains of b. nivea produced the mycotoxin. one strain of b. fulva produced patulin in 11 of 13 processed fruit juices, with greatest amounts being produced in blueberry, red raspberry, and boysenberry juices, whereas no patulin was detected in prune or tomato juices. grown in concord grape juice at 18, 25, 30, ...	1977	596876
some factors affecting the activity of diethylpyrocarbonate as a sterilant.	quantitative data indicated logarithmic death in 5 degrees brix concord grape juice when concentrations of cells under 10(7)/ml were exposed to diethylpyrocarbonate (depc). species differed considerably in their resistance; e.g., 50 ppm reduced the viable count of saccharomyces cerevisiae over nine log(10) cycles, whereas 200 ppm reduced the count of byssochlamys fulva ascospores by only about 1 log. depc lethality was enhanced by higher temperatures; destruction at 40 c was 10- to 100-fold grea ...	1973	4577484
mutagen content of table wines made from various grape species and hybrid cultivars.	the mutagen content of wines produced from the european vitis vinifera grapes was compared with that of wines produced from hybrids of v. vinifera and species indigenous to north america. mutagens were extracted on an xad-2 amberlite resin column and activated with s-9 and/or faecalase in the salmonella/microsomal mutagen assay. all white wines had insignificant mutagen levels. the only red wine to produce statistically significant reversion frequencies was that made from the concord grape. the ...	1984	6373529
specific transfer of 3h from d-[3-3h]gluconic acid into l-tartaric acid in vitaceous plants.	transfer of 3h from d-gluconic acid, specifically labelled with 3h at c-2 or c-3 and 14c at c-1, c-2, or c-3, 4, to l(+)-tartaric acid was examined in leaves and berries of vitis labrusca cv delaware and in leaves of parthenocissus quinquefolia. 3h located at c-3 of d-gluconic acid was highly conserved in this transfer, yielding a 3h/14c ratio between 3.3 and 14 in the light and between 11 and 22 in the dark. these experiments strongly suggest that a portion of the 3h present in l(+)-tartaric ac ...	1994	7765653
production of alternariol and alternariol methyl ether by alternaria alternata grown on fruits at various temperatures.	two toxigenic strains of the fungus alternaria alternata (atcc 56836 and atcc 66868) were grown on surface-disinfected, fresh, ripe fruits and tested for the production of alternariol (aoh) and alternariol methyl ether (ame). examined fruits included strawberries; red and green seedless grapes; concord grapes; red delicious, golden delicious, and gala apples; and blueberries. after inoculation, fruits were incubated at 4, 10 degrees c, or room temperature (approximately 21 degrees c) for up to 3 ...	2001	11307891
isolation and characterization of endothelium-dependent vasorelaxing compounds from grape seeds.	previous work has shown that red wines, grape juices, and other grape products cause endothelium-dependent relaxation (edr) of blood vessels in vitro by increasing nitric oxide production. in this paper we describe the isolation and characterization of some of the compounds responsible for edr activity. concord grape seeds were extracted with methanol and the compounds were separated by toyopearl tsk hw-40s chromatography. resulting fractions (primarily phenolic acids, catechins, and proanthocya ...	2000	11312812
orthologs in arabidopsis thaliana of the hsp70 interacting protein hip.	the hsp70-interacting protein hip binds to the adenosine triphosphatase domain of hsp70, stabilizing it in the adenosine 5'-diphosphate-ligated conformation and promoting binding of target polypeptides. in mammalian cells, hip is a component of the cytoplasmic chaperone heterocomplex that regulates signal transduction via interaction with hormone receptors and protein kinases. analysis of the complete genome sequence of the model flowering plant arabidopsis thaliana revealed 2 genes encoding hip ...	2001	11599566
an lc-ms method for analyzing total resveratrol in grape juice, cranberry juice, and in wine.	resveratrol is an antioxidant found in grapes, grape products, and some other botanical sources with antiinflammatory and anticancer properties. in grapes and wine, it occurs both as free resveratrol and piceid, the 3beta-glucoside of resveratrol. here we report a liquid chromatography-mass spectrometry method to analyze total resveratrol (including free resveratrol and resveratrol from piceid) in fruit products and wine. samples were extracted using methanol, enzymatically hydrolyzed, and analy ...	2002	11804508
vasodilating procyanidins derived from grape seeds.	we have shown in previous work that extracts of grape seeds (gse) and skins, grape juice, and many red wines exhibit endothelium-dependent relaxing (edr) activity in vitro. this edr activity involves endothelial nitric oxide (no) release and subsequent increase in cyclic gmp levels in the vascular smooth muscle cells. the no/cyclic gmp pathway is known to be involved in many cardiovascular-protective roles. the current study focuses on the isolation and identification of edr-active compounds (pr ...	2002	12074963
the hydraulic conductance of the angiosperm leaf lamina: a comparison of three measurement methods.	a comparison was made of three methods for measuring the leaf lamina hydraulic conductance (k(lamina)) for detached mature leaves of six woody temperate angiosperm species. the high-pressure method, the evaporative flux method and the vacuum pump method involve, respectively, pushing, evaporating and pulling water out of the lamina while determining the flow rate into the petiole and the water potential drop across the leaf. tests were made of whether the high-pressure method and vacuum pump met ...	2002	12379784
comparison of the antioxidant effects of concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adults.	concord grape juice (cgj) is a rich source of flavonoids, which have greater antioxidant efficacy in vitro than does alpha-tocopherol; however, the efficacies of flavonoids and alpha-tocopherol in vivo have not been compared.	2002	12450905
antihypertensive, vasodilator and antioxidant effects of a vinifera grape skin extract.	cumulative evidence suggests that moderate wine consumption exerts a cardioprotective effect. we investigated the occurrence of an antihypertensive effect of an alcohol-free hydroalcoholic grape skin extract (gse) obtained from skins of a vinifera grape (vitis labrusca) in experimental rodent hypertension models. the vasodilator effect of gse (polyphenols concentration 55.5 mg g(-1)) was also assessed in the isolated mesenteric vascular bed of wistar rats and the antioxidant effect was studied o ...	2002	12495554
characterization of anthocyanins in grape juices by ion trap liquid chromatography-mass spectrometry.	a reverse phase hplc and electrospray interface with ion trap mass spectrometer method was developed for the characterization of anthocyanins in concord, rubired, and salvador grape juices. rubired and salvador grapes are hybrids from vitis vinifera and vitis rupestris. concord grape is a grape from the native american cultivar vitis labrusca. individual anthocyanins in these three varieties were identified on the basis of uv-vis and ms spectra and further elucidated by ms/ms spectra. anthocyani ...	2003	12643639
both xanthophyll cycle-dependent thermal dissipation and the antioxidant system are up-regulated in grape (vitis labrusca l cv concord) leaves in response to n limitation.	one-year-old grapevines (vitis labrusca l. cv. concord) were supplied with 0, 5, 10, 15, or 20 mm nitrogen (n) in a modified hoagland's solution twice weekly for 4 weeks. as leaf n decreased in response to n limitation, leaf chlorophyll (chl) decreased linearly whereas leaf absorptance declined curvilinearly. compared with high n leaves, low n leaves had lower quantum efficiency of psii as a result of both an increase in non-photochemical quenching (npq) and an increase in closure of psii reacti ...	2003	12885856
continuous production of flor sherry from new york state wines.	flor sherry-like wines were produced continuously from new york state wines from delaware or cold-pressed concord grapes whose pigment contents were reduced with activated carbon. the course of flor fermentation was followed by total aldehyde analysis. optimal flor production was observed at 18 to 20 c. two continuous methods of fermentation were used. a glass column packed with ceramic saddles densely covered with yeasts gave good results, but required more careful management than the second me ...	1965	14339255
inhibition of rat mammary tumorigenesis by concord grape juice constituents.	the effects of concord grape juice constituents on the promotion of chemically induced rat mammary tumor development and on the proliferation of a rat mammary adenocarcinoma cell line were studied. isocaloric grape juice formulations provided in the drinking fluid of rats at concentrations of 489 and 651 mg of phenolics/dl of fluid significantly inhibited mammary adenocarcinoma multiplicity compared to controls. final tumor mass also was significantly decreased for animals provided these two gra ...	2003	14640571
molecular genetic diversity of the french-american grapevine hybrids cultivated in north america.	french-american hybrid grapevines are most popular in eastern and mid-western north america: they are hardy cultivars derived from crosses between the european vitis vinifera and american wild vines. the aim of this study was to characterize their genetic background using 6 microsatellite (ssr) markers and a set of 33 diagnostic rapd markers. the latter were reproducible with different pcr thermal cyclers. two ssr loci were found to be synonymous, vrzag47 and vvmd27. the dna profile frequencies ...	2003	14663522
genotoxic evaluation of a vinifera skin extract that present pharmacological activities.	toxicity of an alcohol-free hydro-alcoholic grape skin extract (gse) obtained from red grapes vitis labrusca (isabel varietal) that present antihypertensive, vasodilator and antioxidant effects was estimated by different bioassays. using the salmonella/microsome assay for strains ta97, ta98, ta100 and ta102 no mutagenicity was detected for all tested concentrations (0.1-100 microg/ml), even with metabolization. nevertheless, cytotoxicity was observed for ta97 and ta102 with and without metaboliz ...	2004	15110106
anthocyanin quantification and radical scavenging capacity of concord, norton, and marechal foch grapes and wines.	the anthocyanin content and the radical scavenging capacity of three non-vitis vinifera grapes (marechal foch, norton, and concord varieties) were determined. analyses of anthocyanins in the skin (s) and wine (w) of these grape varieties were performed by spectrophotometry, hplc with electrochemical detection, and matrix-assisted laser desorption ionization (maldi). the total anthocyanin contents of s samples were 258 +/- 37 mg/100 g of wet weight for foch, 888 +/- 78 mg/100 g for norton, and 32 ...	2004	15506816
concord grape juice supplementation reduces blood pressure in korean hypertensive men: double-blind, placebo controlled intervention trial.	many of the flavonoids found in grapes and grape products such as juice or wine have been known to exert antioxidant, anti-inflammatory, platelet inhibitory and arterial relaxing effects either in vitro, in animal studies and in human trials. this study was designed to test the effect of concord grape juice consumption on altering blood pressure in hypertensive patients. forty subjects were given 5.5 ml/kg body weight/day of either concord grape juice (cgj) or a calorie-matched placebo drink eve ...	2004	15630270
systematic identification and characterization of anthocyanins by hplc-esi-ms/ms in common foods in the united states: fruits and berries.	anthocyanins were systematically identified and characterized by hplc-esi-ms/ms coupled with diode array detection in common fruits from u.s. food markets and other commercial sources. of the 25 different fruits that were screened, 14 fruits were found to contain anthocyanins; the number of anthocyanins varied from 2 in peaches and nectarines to 31 in concord grape. the individual anthocyanins were identified by comparing their mass spectral data and retention times with those of standards and p ...	2005	15796599
evaluation of photo-mutagenicity and photo-cytotoxicity of food coloring agents.	pigments extracted from natural products are widely used for food coloration in japan. an investigation concerning the photo-mutagenicity and photo-carcinogenicity of frequently used colorants in japan was performed. colorants examined were from laccifer lacca (lac-color), coccus cacti (cochineal-color), carthamus tinctorius (carthamus yellow), gardenia augusta (gardenia yellow and gardenia blue), monascus anka and monascus purpureus (monascus red), the skin of vitis vinifera and vitis labrusca ...	2005	15843386
purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (dmba)-induced rat mammary tumorigenesis and in vivo dmba-dna adduct formation.	there has been considerable interest in identifying specific foods and phytochemicals that may have breast cancer preventive properties. concord grapes are rich in polyphenolic chemicals and anthocyanin pigments that may have biological properties which could suppress cancer such as having antioxidant, antiproliferative, and proapoptotic actions. to determine the potential breast cancer protective action of purple grape juice, we examined the effect of grape juice consumption on the initiation s ...	2006	15878797
mechanism of the endothelium-dependent vasodilator effect of an alcohol-free extract obtained from a vinifera grape skin.	an alcohol-free grape-skin extract (gse) obtained from skins of vitis labrusca has significant anti-hypertensive, antioxidant and vasodilator effects. according to our previous results, the vasodilator effect of gse in the isolated mesenteric vascular bed (mvb) of the rat is dependent on endothelium and partially dependent on nitric oxide (no). in the mvb of the rat pre-contracted with norepinephrine (ne), bolus injections of gse induced a long-lasting dose-dependent vasodilation that is signifi ...	2005	16023862
canopy and environmental control of root dynamics in a long-term study of concord grape.	below-ground carbon allocation represents a substantial fraction of net photosynthesis in plants, yet timing of below-ground allocation and endogenous and exogenous factors controlling it are poorly understood. minirhizotron techniques were used to examine root populations of vitis labruscana bailey cv. concord under two levels of dormant-season canopy removal and irrigation. root production, pigmentation, death and disappearance to a depth of 110 cm were determined over two wet and two dry year ...	2005	16101919
interactive effects of soil temperature and moisture on concord grape root respiration.	root respiration has important implications for understanding plant growth as well as terrestrial carbon flux with a changing climate. although soil temperature and soil moisture often interact, rarely have these interactions on root respiration been studied. this report is on the individual and combined effects of soil moisture and temperature on respiratory responses of single branch roots of 1-year-old concord grape (vitis labruscana bailey) vines grown in a greenhouse. under moist soil condi ...	2005	16143721
the biosynthesis and regulation of biosynthesis of concord grape fruit esters, including 'foxy' methylanthranilate.	the biosynthesis of methyl anthranilate, the volatile compound responsible for the distinctive 'foxy' aroma and flavor of the washington concord grape (vitis labrusca), involves an alcohol acyltransferase that catalyzes the formation of methyl anthranilate from anthraniloyl-coenzyme a (coa) and methanol. although methanol is a poor substrate in comparison with the co-substrate, high levels of this acyltransferase (0.5% of the total protein) combined with relatively high levels of this alcohol ma ...	2005	16262710
enumeration of byssochlamys and other heat-resistant molds.	methods for the detection of low numbers of heat-resistant molds on fruits were studied by using cultures of byssochlamys and a number of unidentified mold isolates. ascospore dormancy had a marked effect on viable recoveries, and the medium in which ascospores were heated influenced activation rates. best results were obtained when fruit homogenates were heated for 60 min at 70 c in concord grape juice, followed by culturing on acidified potato dextrose agar.	1970	16349886
abscisic acid stimulates a calcium-dependent protein kinase in grape berry.	it has been demonstrated that calcium plays a central role in mediating abscisic acid (aba) signaling, but many of the ca2+-binding sensory proteins as the components of the aba-signaling pathway remain to be elucidated. here we identified, characterized, and purified a 58-kd aba-stimulated calcium-dependent protein kinase from the mesocarp of grape berries (vitis vinifera x vitis labrusca), designated acpk1 (for aba-stimulated calcium-dependent protein kinase1). aba stimulates acpk1 in a dose-d ...	2006	16407437
effects of concord grape juice on cognitive and motor deficits in aging.	animals and humans show increased motor and cognitive declines with aging that are thought to be due to increased susceptibility to the long-term effects of oxidative stress and inflammation. previous findings have suggested that reversals in these age-related declines might be accomplished by increasing the dietary intake of polyphenolics found in fruits and vegetables, especially those identified as being high in antioxidant and anti-inflammatory activities.	2006	16412610
pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide.	pomegranate juice (pj), which is a rich source of potent flavonoid antioxidants, was tested for its capacity to protect nitric oxide (no) against oxidative destruction and enhance the biological actions of no. employing chemiluminescence headspace analysis, pj was found to be a potent inhibitor of superoxide anion-mediated disappearance of no. pj was much more potent than concord grape juice, blueberry juice, red wine, ascorbic acid, and dl-alpha-tocopherol. as little as 3 microl of a 6-fold dil ...	2006	16626982
translocation of sugars in the concord grape.		1958	16655073
stereoisomeric characterization of tartaric acid produced during l-ascorbic acid metabolism in plants.	labeled tartaric acids from pelargonium crispum apices which had been fed l-ascorbic acid-6-(14)c and vitis labrusca and parthenocissus inserta tissues which had been fed l-ascorbic acid-1-(14)c were examined by chemical means to determine chiral configuration. in each instance, label was associated with (+)-tartaric acid.similar experiments with labeled tartaric acid from p. crispum which had been labeled with d-glucose-1-(14)c or -6-(14)c led to the same result. no evidence was obtained for fo ...	1975	16659212
biosynthesis of (+)-tartaric acid from l-[4-c]ascorbic acid in grape and geranium.	the metabolic fate of l-[4-(14)c]ascorbic acid has been examined in the grape (vitis labrusca l.) and lemon geranium (pelargonium crispum l. l'hér. cv. prince rupert) under conditions comparable to data from l-[1-(14)c]ascorbic acid and l-[6-(14)c]ascorbic acid experiments. in detached grape leaves and immature berries, l-[4-(14)c]ascorbic acid and l-[1-(14)c]ascorbic acid were equivalent precursors to carboxyl labeled (+)-tartaric acid. in geranium apices, l-[4-(14)c]ascorbic acid yielded inter ...	1978	16660361
conversion of labeled substrates to sugars, cell wall polysaccharides, and tartaric acid in grape berries.	[u-(14)c]sucrose, myo-[u-(14)c]inositol, [6-(14)c]- and [u-(14)c]glucuronate, udp-[u-(14)c]glucuronate, [u-(14)c]gluconate, and l-[1-(14)c]ascorbic acid were fed into grape berries, vitis labrusca l. cv. delaware, at intervals throughout the ripening process and incorporation of (14)c into several metabolites was studied.[u-(14)c]sucrose was the most effective precursor of cellulose in young grape berries and of glucose and fructose in mature berries. on the other hand, udp-[u-(14)c]glucuronate ...	1978	16660488
synthesis of l-(+)-tartaric acid from l-ascorbic acid via 5-keto-d-gluconic acid in grapes.	5-keto-l-idionic acid ( identical with5-keto-d-gluconic acid, d-xylo-5-hexulosonic acid) was found as a metabolic product of l-ascorbic acid in slices of immature grapes, vitis labrusca l. cv ;delaware'. specifically labeled compounds, recognized as metabolic products of l-ascorbic acid in grapes, were fed to young grape tissues to investigate the metabolic pathway from l-ascorbic acid to l-(+)-tartaric acid.label from dehydro-l-[1-(14)c]ascorbic acid, 2-keto-l-[1-(14)c]idonic acid (l-xylo-2-hex ...	1984	16663792
spring filling of xylem vessels in wild grapevine.	xylem vessels in grapevines vitis labrusca l. and vitis riparia michx. growing in new england contained air over winter and yet filled with xylem sap and recovered their maximum hydraulic conductance during the month before leaf expansion in late may. during this period root pressures between 10 and 100 kilopascals were measured. although some air in vessels apparently dissolved in ascending xylem sap, results indicated that some is pushed out of vessels and then out of the vine. air in the vess ...	1987	16665259
concord grape juice attenuates platelet aggregation, serum cholesterol and development of atheroma in hypercholesterolemic rabbits.	intake of concord grape juice (cgj), rich in polyphenolics, inhibits platelet aggregation (pa), a risk factor for cardiovascular disease (cvd), in normocholesterolemic animals and humans. it is unclear whether cgj can attenuate hypercholesterolemia-enhanced pa. the effects of daily cgj consumption on hypercholesterolemia-enhanced pa and the development of atherosclerosis were investigated. two groups of rabbits (control and treated; n=10 each) were fed a hypercholesterolemic diet for 48 days. tr ...	2007	16780846
a shift of phloem unloading from symplasmic to apoplasmic pathway is involved in developmental onset of ripening in grape berry.	it remains unclear whether the phloem unloading pathway alters to adapt to developmental transition in fleshy fruits that accumulate high level of soluble sugars. using a combination of electron microscopy, transport of the phloem-mobile symplasmic tracer carboxyfluorescein, movement of the companion cell-expressed and the green fluorescent protein-tagged viral movement protein, and assays of the sucrose cleavage enzymes, the pathway of phloem unloading was studied in the berries of a hybrid gra ...	2006	16861573
grape juice causes endothelium-dependent relaxation via a redox-sensitive src- and akt-dependent activation of enos.	an enhanced endothelial formation of nitric oxide (no) and endothelium-derived hyperpolarizing factor (edhf), is thought to contribute to the protective effect of moderate consumption of red wine on coronary diseases. the present study has characterized endothelium-dependent relaxations to concord grape juice (cgj), a non-alcoholic rich source of grape-derived polyphenols, in the coronary artery.	2007	16962569
mesocarp localization of a bi-functional resveratrol/hydroxycinnamic acid glucosyltransferase of concord grape (vitis labrusca).	resveratrol is a stilbene with well-known health-promoting effects in humans that is produced constitutively or accumulates as a phytoalexin in several plant species including grape (vitis sp.). grape berries accumulate stilbenes in the exocarp as cis- and trans-isomers of resveratrol, together with their respective 3-o-monoglucosides. an enzyme glucosylating cis- and trans-resveratrol was purified to apparent homogeneity from concord (vitis labrusca) grape berries, and peptide sequencing associ ...	2007	17270014
improved high performance liquid chromatographic separation of anthocyanin compounds from grapes using a novel mixed-mode ion-exchange reversed-phase column.	a novel mixed mode hplc method using a column combining both ion-exchange and reversed-phase separation mechanisms has been developed to facilitate analysis of anthocyanins in grapes. chromatographic performance and subsequent analysis of anthocyanidin diglucosides and acylated compounds are significantly improved using the new column, compared to those associated with conventional c18 reversed-phase methods. the mixed mode column produces a distinctive eluting pattern for the different anthocya ...	2007	17382950
anthocyanin-rich grape extract blocks breast cell dna damage.	anthocyanins, belonging to the flavonoid family of phytochemicals, have received attention as agents that may have potential in preventing chronic diseases such as cardiovascular diseases and certain cancers. in the present study, an anthocyanin-rich extract from concord grapes [referred to as concord grape extract (cge)] and the anthocyanin delphinidin were evaluated for their capacity to inhibit dna adduct formation due to the environmental carcinogen benzo[a]pyrene (bp) in mcf-10f cells, a no ...	2007	17651059
fractionation of monomeric and polymeric anthocyainins from concord grape (vitis labrusca l.) juice by membrane ultrafiltration.	concord grape juice with 20% polymeric and 60% monomeric anthocyanin (acy) forms was ultrafiltrated using polyvinylidene fluoride flat sheet membranes ranging from 10 to 1000 k molecular weight cutoff (mwco) to obtain different permeate and retentate fractions. permeate flux, membrane resistance, acy rejection, fouling, acy content and composition, color properties, and antioxidant activity (aox) were characterized. results showed that permeate flux declined with lower mwco, while membrane resis ...	2007	17665929
phenolic content and antioxidant activities of white and purple juices manufactured with organically- or conventionally-produced grapes.	although the beneficial effects of moderate wine intake are well-known, data on antioxidant capacity of grape juices are scarce and controversial. the purpose of this study was to quantify total polyphenols, anthocyanins, resveratrol, catechin, epicatechin, procyanidins, and ascorbic acid contents in grape juices, and to assess their possible antioxidant activity. eight vitis labrusca juices--white or purple, from organically- or conventionally-grown grapes, and obtained in pilot or commercial s ...	2007	17683842
comparison of antioxidant potency of commonly consumed polyphenol-rich beverages in the united states.	a number of different beverage products claim to have antioxidant potency due to their perceived high content of polyphenols. basic and applied research indicates that pomegranate juice (pj), produced from the wonderful variety of punica granatum fruits, has strong antioxidant activity and related health benefits. although consumers are familiar with the concept of free radicals and antioxidants, they are often misled by claims of superior antioxidant activity of different beverages, which are u ...	2008	18220345
influence of pressing method on juice stilbene content in muscadine and bunch grapes.	juice stilbene contents of 2 muscadine (vitis rotundifolia) cultivars, noble and carlos, and 2 bunch grape (vitis labrusca) cultivars, mid south and miss blanc were evaluated after crushing and pressing. four commercial pressing methods were used to produce juice: (1) cold press of fresh berries (cp); (2) hot press of fresh berries (hp); (3) cold press of frozen and thawed berries (fcp); and (4) cold press of pectolytic enzyme treated berries (ecp). free run juice (frj) from the crusher without ...	2008	18460131
identification of a powerful aroma compound in munster and camembert cheeses: ethyl 3-mercaptopropionate.	with the view to investigate the presence of thiols in cheese, the use of different methods of preparation and extraction with an organomercuric compound ( p-hydroxymercuribenzoate) enabled the isolation of a new compound. the analysis of cheese extracts by gas chromatography coupled with pulse flame photometry, mass spectrometry, and olfactometry detections led to the identification of ethyl 3-mercaptopropionate in munster and camembert cheeses. this compound, described at low concentrations as ...	2008	18512934
mating disruption of paralobesia viteana in vineyards using pheromone deployed in splat-gbm wax droplets.	a paraffin wax formulation releasing pheromone for mating disruption of insects was tested during 2005 and 2006 in vitis labrusca vineyards infested by grape berry moth, paralobesia viteana (lepidoptera: tortricidae). in early may of each year, 1-ml droplets of splat-gbm wax containing 3% sex pheromone of p. viteana were applied to every wooden post at a rate of 400/ha in replicated 1.3-ha plots. moth captures in sex pheromone baited traps placed at the vineyard borders and interiors revealed si ...	2008	18581179
genomic and genetic analysis of myb-related genes that regulate anthocyanin biosynthesis in grape berry skin.	as a result of natural hybridization and human selection over millennia, the skin colors of grapes have become greatly diversified. the color is determined by the quantity and composition of anthocyanins. color-skinned cultivars accumulate anthocyanins in their skins, whereas white-skinned cultivars do not. myb-related transcription-factor genes such as vvmyba1 regulate anthocyanin biosynthesis. vvmyba2r, vlmyba1-1, vlmyba1-2, and vlmyba2, which are homologs of vvmyba1, also regulate anthocyanin ...	2008	18651125
biological control of botrytis cinerea by volatiles of 'isabella' grapes.	abstract the effect of volatiles from cv. isabella (vitis labrusca) on the growth of botrytis cinerea was tested in vitro and in situ, in the latter case on 'roditis' grapes (v. vinifera), at various temperatures. the goal of the research was to determine whether the volatiles emitted by isabella grapes could be effective biocontrol agents of botrytis cinerea. the closed mariotte system was used as a bioassay method to analyze quantitatively the biological action of these volatiles on fungal gro ...	2004	18943068
postharvest biological control of botrytis cinerea on kiwifruit by volatiles of [isabella] grapes.	abstract the potential of volatile substances emitted by 'isabella' grapes (vitis labrusca) to control gray mold (botrytis cinerea) on 'hayward' kiwifruit (actinidia deliciosa) was studied. the closed mariotte system was used as a bioassay method to analyze quantitatively the biological action of these volatiles on b. cinerea growth. in vivo experiments compared the effects of volatiles from 'isabella' grapes versus volatiles from 'roditis' grapes (v. vinifera) and a b. cinerea control on the gr ...	2004	18943697
the epidemiology of powdery mildew on concord grapes.	abstract vitis labruscana 'concord' is a grape cultivar widely grown in the united states for processing into juice and other grape products. concord grapes are sporadically but sometimes severely damaged by the grape powdery mildew pathogen, uncinula necator. although the foliage is often reported to be moderately resistant to powdery mildew, severe fruit infection occurs in some years. we observed the seasonal development of powdery mildew on leaves, rachises, and berries of unsprayed concord ...	2001	18944121
chloroplast microsatellites markers to assess genetic diversity in wild and cultivated grapevines of iran.	to assess the haplotype diversity and genetic relationship between them, a set of 69 iranian cultivated accessions, six european cultivars and an accession of vitis labrusca along with 63 wild grapevine individuals were studied using chloroplast microsatellite markers. results showed that among analyzed cpssr loci only ccmp 3 and ccmp10 were polymorphic within cultivars and only ccmp3 was polymorphic in wild grape individuals. the size variants of both loci combine in a total of 4 different hapl ...	2007	19086550
population trends and vertical distribution of plant-parasitic nematodes associated with vitis labrusca l. in michigan.	nematode population trends and vertical distribution were monitored in a southwest michigan vineyard (vitis labrusca cv. concord) from 1976 through 1983. shallow (20 cm) and deep (90 cm) applications of 1,3-dichloropropene applied at 281 (shallow) plus 658 or 1,122 (deep) liters/ ha provided excellent control of xiphinema americanum, criconemella xenoplax, and meloidogyne hapla. populations of x. americanum remained below detectable levels for the entire 8-year experimental period where the fumi ...	1985	19294066
reproduction and pathogenicity of three isolates of meloidogyne hapla race a on concord grapes.		1980	19300676
description of meloidogyne nataliei n. sp. (nematoda: meloidogynidae) from grape (vitis labrusca) in michigan, with sem observations.	meloidogyne nataliei n. sp. is described and illustrated from grape (vitis labrusca) in a declining vineyard at mattawan, michigan, usa. infected grape roots exhibit no hyperplastic symptoms. females protrude from the roots and are surrounded by a massive egg sac containing many eggs. this new species is distinguishable from other species of the genus especially by its large, striking perineal pattern with, usually, two ropelike separated striae on each side extending laterally from the vulval a ...	1981	19300781
effects of macroposthonia xenoplax on the growth of concord grape.	concord grape (vitis labrusca) plants were inoculated with macroposthonia xenoplax at levels of 100, 1,000, and 10,000 nematodes. after 4 months, plants inoculated with 10,000 m. xenoplax were stunted, and root systems were darker and had fewer feeder roots than those in other treatments. the lower nematode inoculation levels suppressed top growth but did not affect root growth. m. xenoplax reproduced well on concord grapes.	1977	19305597
grape juice, berries, and walnuts affect brain aging and behavior.	numerous studies have indicated that individuals consuming a diet containing high amounts of fruits and vegetables exhibit fewer age-related diseases such as alzheimer's disease. research from our laboratory has suggested that dietary supplementation with fruit or vegetable extracts high in antioxidants (e.g. blueberries, strawberries, walnuts, and concord grape juice) can decrease the enhanced vulnerability to oxidative stress that occurs in aging and these reductions are expressed as improveme ...	2009	19640963
grape consumption supports immunity in animals and humans.	all nutrients play a role in maintaining the immune system and providing substrate for the response. gammadelta t cells, on the other hand, seem to have a unique response to certain dietary bioactive components found in the plant family. although the identification of those components is not well known yet, members of the proanthocyanidin family and the anthocyanin family of compounds are candidates. because grapes and grape products contain both of these types of compounds, i hypothesized that ...	2009	19640969
phenolic content of grapevine leaves (vitis labrusca var. bordo) and its neuroprotective effect against peroxide damage.	in some countries, leaves of vitis vinifera grapes have been used for food and for treating many medical disorders. however, there are no studies on the leaves of vitis labrusca, the main species used for wine and juice production in south america. in this work, the phenolic compounds and antioxidant activity of organic and conventional grape leaves extracts prepared from v. labrusca (var. bordo) in brain tissues (in vitro model) have been evaluated. both organic and conventional grape leaves ex ...	2010	19699291
purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet.	male c57bl/6 mice received diets with either 10% of kcal from fat, or a high fat diet [45% (hf45) or 60% (hf60) kcal from fat]. diets were prepared with or without freeze-dried powders (10%) from whole blueberries (bb), strawberries (sb), concord grape or black raspberry. in the 2nd study, purified anthocyanins (acns) from sb or bb were added to the drinking water of the treatments fed the hf60 diet. in study 1, serum triglycerides were increased by feeding the hf45 diet but were elevated furthe ...	2009	19743407
subcritical solvent extraction of procyanidins from dried red grape pomace.	procyanidins in dried sunbelt ( vitis labrusca l.) red grape pomace were extracted using accelerated solvent extraction (ase) with pressure (6.8 mpa), one extraction cycle, and temperature (40, 60, 80, 100, 120, and 140 degrees c). six ethanol/water solvents (0, 10, 30, 50, 70, and 90%, v/v) were compared to conventional extraction with acetone/water/acetic acid (70:29.5:0.5, v/v/v). procyanidins in the extracts were identified by hplc-esi-ms/ms and contained degrees of polymerization (dp) of 1- ...	2010	20020688
concord grape juice supplementation improves memory function in older adults with mild cognitive impairment.	concord grape juice contains polyphenol compounds, which have antioxidant and anti-inflammatory properties and influence neuronal signalling. concord grape juice supplementation has been shown to reduce inflammation, blood pressure and vascular pathology in individuals with cvd, and consumption of such flavonoid-containing foods is associated with a reduced risk for dementia. in addition, preliminary animal data have indicated improvement in memory and motor function with grape juice supplementa ...	2010	20028599
effect of concord grape juice on chemotherapy-induced nausea and vomiting: results of a pilot study.	to determine the feasibility of administering a flavonoid-rich adjunctive treatment (concord grape juice) for the management of chemotherapy-induced nausea and vomiting (cinv); to evaluate the usefulness of existing measures for assessing cinv frequency and severity, quality of life, control over life events, and psychological state; to identify any actual or potential adverse events associated with frequent grape juice intake; and to provide preliminary data concerning the effect of concord gra ...	2010	20189927
effects of concord grape juice on appetite, diet, body weight, lipid profile, and antioxidant status of adults.	concord grape juice (cgj) is a rich source of phenolic antioxidants, with a range of putative health benefits. however, high beverage energy and fructose intake may lead to weight gain and insulin resistance, respectively. this study assessed the effects of cgj consumption for 12 weeks on appetite, diet, body weight, lipid profile, and antioxidant status.	2009	20439553
impact of multicolored asian lady beetles on the sensory properties of concord and niagara grape juice.	the presence of multicolored asian lady beetles (malb) in grape juice is increasingly problematic. the overall objective of this study was to determine the specific sensory impacts of malb on concord and niagara grape juice. the aroma threshold for malb-taint in both juices was determined and expressed as the best estimate threshold (bet). the aroma bet for malb-taint in concord grape juice was 1.8 and 0.65 malb/l niagara grape juice. the specific sensory attributes of the grape juices influence ...	2017	20492204
impact of harvesting and processing conditions on green leaf volatile development and phenolics in concord grape juice.	the disruption of plant cell walls during fruit juice processing results in the enzymatic formation of herbaceous-smelling green leaf volatiles (glvs). our objective was to assess the impact of thermal processing conditions on resulting levels of glvs (hexanal, trans-2-hexenal, hexanol, cis-3-hexenol, and trans-2-hexenol), total phenols, monomeric anthocyanins, and percent polymeric color in concord grape juice. the effects of fruit maturity and stage of juice processing on juice glv content was ...	2010	20492283
comparison of high-performance liquid chromatography separation of red wine anthocyanins on a mixed-mode ion-exchange reversed-phase and on a reversed-phase column.	anthocyanins, which confer the characteristic color to red wine, can be used as markers to classify wines according to the grape variety. it is a complex separation that requires very high chromatographic efficiency, especially in the case of aged red wines, due to the formation of pyranoanthocyanins. a coelution between these kinds of compounds can affect the r(ac/coum) ratio of aged wines, and might lead to false results when classifying the wine variety. in 2007, the use of a novel mixed-mode ...	2010	20688332
effects of concord grape juice on ambulatory blood pressure in prehypertension and stage 1 hypertension.	consumption of flavonoid-containing foods may be useful for the management of hypertension.	2010	20844075
effects of concentration prior to cold-stabilization on anthocyanin stability in concord grape juice.	the color of concord grape juice produced by concentration before cold-stabilization and detartration (direct-to-concentrate, dtc) was compared to juice produced via cold-stabilization prior to concentration (standard concentrate, sc) and evaluated by several metrics. using the boulton copigmentation assay, the majority of the absorbance at 520 nm in bottled sc juice (72%) was due to monomeric anthocyanins. following reconstitution, dtc juice had a 63% greater absorbance at 520 nm than sc juice. ...	2010	20929230
modulation of the root-sourced aba signal along its way to the shoot in vitis riparia x vitis labrusca under water deficit.	the intensity of the root-sourced abscisic acid (aba) signal has long been thought to decrease along its long-distance transport pathway, and hence the shoot responses to the aba signal would be expected to become less sensitive with the increase in plant height. it is reported here that there is a significant modification of the aba signal intensity in its pathway to leaves in grapevine (vitis riparia×vitis labrusca), but in contrast to the expectation that the aba signal intensity may decrease ...	2011	21131549
regular consumption of concord grape juice benefits human immunity.	γδ t cells are important immune surveillance cells residing in epithelial layers lining the intestine, lung, and reproductive tract. the main objective of this study was to test the hypothesis that consumption of dietary compounds from grapes would modify γδ t-cell function. other factors related to immune function after grape juice consumption were also tested. a randomized, double-blind, placebo-controlled, parallel intervention was conducted: 100% grape juice made from concord grapes or a pla ...	2010	21138361
evaluation of the potential protective effects of ad libitum black grape juice against liver oxidative damage in whole-body acute x-irradiated rats.	the aim of this study was to evaluate the potential protective effects of ad libitum black grape (vitis labrusca) juice against liver oxidative damage in whole-body acute x-irradiated rats.	2011	21266186
molecular cloning and biochemical characterization of three concord grape (vitis labrusca) flavonol 7-o-glucosyltransferases.	grapes berries produce and accumulate many reactive secondary metabolites, and encounter a wide range of pathogen- and human-derived xenobiotic compounds. the enzymatic glucosylation of these metabolites changes their reactivity, stability and subcellular location. two ests with more than 90% nucleotide sequence identity to three full-length glucosyltransferases are expressed in several grape tissues. the full-length clones have more than 60% amino acid sequence similarity to previously characte ...	2011	21755362
identification of (poly)phenolic compounds in concord grape juice and their metabolites in human plasma and urine after juice consumption.	analysis of concord grape juice by hplc with esi-msn, pda and fluorescence detection resulted in the identification and quantification of 60 flavonoids and related phenolic compounds which were present at an overall concentration of 1508 ± 31 µmol/l. a total of 25 anthocyanins were detected, which were mono- and di-o-glucosides, o-acetylglucosides, o-p-coumaroyl-o-diglucosides and o-p-coumaroylglucosides of delphinidin, cyanidin, petunidin, peonidin and malvidin. the anthocyanins represented 46% ...	2011	21812481
comparison of odor-active compounds in grapes and wines from vitis vinifera and non-foxy american grape species.	native american grape (vitis) species have many desirable properties for winegrape breeding, but hybrids of these non-vinifera wild grapes with vitis vinifera often have undesirable aromas. other than the foxy-smelling compounds in vitis labrusca and vitis rotundifolia , the aromas inherent to american vitis species are not well characterized. in this paper, the key odorants in wine produced from the american grape species vitis riparia and vitis cinerea were characterized in comparison to wine ...	2011	21879766
a novel attractant for anastrepha ludens (diptera: tephritidae) from a concord grape product.	an attractant for mexican fruit fly, anastrepha ludens (loew) (diptera: tephritidae), was developed from a commercial product called sabor uva containing processed concord grape juice. the principal volatile components of sabor uva aroma were identified and an aqueous mixture of 15 components that was gas chromatographically similar to sabor uva was prepared. this mixture was equivalent to sabor uva in attractiveness by using wind-tunnel bioassays. after deleting chemicals that did not contribut ...	2011	21882683
characterization of red wines from south america based on sensory properties and antioxidant activity.	it is widely accepted that red wines constitute one of the most important sources of dietary polyphenolic antioxidants. however, it is still not known how some variables such as variety, vintage, country of origin, and retail price are associated with the antioxidant activity and sensory profile of south american red wines. in this regard, 80 samples produced in brazil, chile and argentina were assessed in relation to their sensory properties, color and in vitro antioxidant activity, and results ...	2012	21969030
rainfastness and residual activity of insecticides to control japanese beetle (coleoptera: scarabaeidae) in grapes.	field-based bioassays and residue profile analysis were used to determine the relative toxicity, rainfastness, and field degradation over time of five insecticides from five insecticide classes on adult japanese beetles, popillia japonica newman (coleoptera: scarabaeidae), in grapes, vitis labrusca l. bioassays assessed japanese beetle condition as alive, knockdown, or immobile when exposed for 24 h or 7-d field-aged residues of phosmet, carbaryl, bifenthrin, thiamethoxam, or indoxacarb after 0, ...	2011	22066196
molecular cloning and biochemical characterization of the udp-glucose: flavonoid 3-o-glucosyltransferase from concord grape (vitis labrusca).	glucosylation of anthocyanidin substrates at the 3-o-position is crucial for the red pigmentation of grape berries and wine. the gene that encodes the enzyme involved in this reaction has been cloned from vitis labrusca cv. concord, heterologously expressed, and the recombinant enzyme (rvl3gt) was characterized. vl3gt has 96% amino acid sequence identity with vitis vinifera vv3gt and groups phylogenetically with several other flavonoid 3-o-glycosyltransferases. in vitro substrate specificity stu ...	2012	22098678
phenolic composition of the edible parts (flesh and skin) of bordô grape (vitis labrusca) using hplc-dad-esi-ms/ms.	the aim of this study was the detailed characterization of the phenolic composition and the determination of the antioxidant activity of the bordô grape (vitis labrusca) cultivated in south brazil. the edible parts of bordô grapes (flesh and skin) contained 1130 mg/kg of total phenolic compounds (as gallic acid), mainly located in the skins. anthocyanin content in the skins was high, largely as 3,5-diglucosides (1359 mg/kg, as malvidin 3,5-diglucoside). total flavonols accounted for 154 μmol/kg, ...	2011	22112247
hepatoprotective, cardioprotective, and renal-protective effects of organic and conventional grapevine leaf extracts on wistar rat tissues.	the purpose of this study was to evaluate the beneficial effects of organic and conventional grapevine (vitis labrusca l.) leaf extracts in reducing hydrogen peroxide-induced stress in the liver, heart and kidney of wistar rats by measuring lipids and proteins damages (carbonyl assay), as well as the activity of the antioxidant enzymes superoxide dismutase and catalase. the preincubation with 5 mg/ml of organic and conventional grapevine (vitis labrusca l.) leaf extracts prevented both lipids an ...	2011	22146965
gastrointestinal stability and bioavailability of (poly)phenolic compounds following ingestion of concord grape juice by humans.	the in vitro gastrointestinal stability of (poly)phenolic compounds in concord grape juice was compared with recoveries in ileal fluid after the ingestion of the juice by ileostomists. recoveries in ileal fluid indicated that 67% of hydroxycinnamate tartarate esters, and smaller percentages of the intake of other (poly)phenolic compounds, pass from the small intestine to the colon. the juice was also ingested by healthy subjects with an intact functioning colon. peak plasma concentrations (c(max ...	2012	22331633
assessment of the validity of maturity metrics for predicting the volatile composition of concord grape juice.	total soluble solids (tss) are typically used as the sole metric for maturity of concord grapes. however, the reliability of tss in predicting the aroma composition of finished juice for grapes sourced from multiple sites has not been investigated. this study sought to determine the validity of tss in predicting the aroma composition of the juice while also investigating other potentially useful indicators, including ph, titratable acidity (ta), and tss:ta ratio. grapes were harvested from 9 sit ...	2012	22384957
biochemical analysis and in vivo hypoglycemic activity of a grape polyphenol-soybean flour complex.	defatted soybean flour (dsf) can efficiently sorb, concentrate, and stabilize polyphenols, but not sugars, from concord grape juice, to yield grape polyphenol-enriched dsf. sorption of grape polyphenols to dsf particles was dependent on the ratio of dsf and grape juice concentrate used, but not time of mixing or ph. depending on ratios of starting materials, 1 g of grape polyphenol-enriched dsf contained 1.6-10.4 mg of anthocyanins, 7.5-93.1 mg of proanthocyanidins, and 20.5-144.5 mg of total po ...	2012	22462390
concord grape juice supplementation and neurocognitive function in human aging.	polyphenol compounds found in berry fruits, in particular flavonoids, have been associated with health benefits including improvement in cognition and neuronal function with aging. concord grape juice contains polyphenols, including anthocyanins and flavanols, and previous research has shown improvement in a number of human health conditions with grape juice supplementation. in the current study, older adult subjects with mild cognitive impairment consumed concord grape juice or placebo for 16 w ...	2012	22468945
supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape.	supercritical fluid extraction has been widely employed in the extraction of high purity substances. in this study, we used the technology to obtain oil from seeds from a variety of grapes, from vinification residues generated in the southern region of the state of rio grande do sul, brazil. this work encompasses three varieties of vitis vinifera (moscato giallo, merlot, and cabernet sauvignon) and two of vitis labrusca (bordô e isabel), harvested in 2005 and 2006. we obtained the highest oil co ...	2012	22593706
comparison of a retrotransposon-based marker with microsatellite markers for discriminating accessions of vitis vinifera.	identification and knowledge concerning genetic diversity are fundamental for efficient management and use of grapevine germplasm. recently, new types of molecular markers have been developed, such as retrotransposon-based markers. because of their multilocus pattern, retrotransposon-based markers might be able to differentiate grapevine accessions with just one pair of primers. in order to evaluate the efficiency of this type of marker, we compared retrotransposon marker tvv1 with seven microsa ...	2012	22653601
metabolite profiling of jaboticaba (myrciaria cauliflora) and other dark-colored fruit juices.	many dark-colored fruit juices, rich in anthocyanins, are thought to be important for human health. joboticaba (myrciaria cauliflora) fruits, native to brazil, have phenolics including anthocyanins and are processed into juice and other products. the phenolic constituents in the fruits of jaboticaba were studied by high-performance liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry. twenty-two compounds were identified or tentatively determined by detaile ...	2012	22809264
anti-atherogenic effects of a phenol-rich fraction from brazilian red wine (vitis labrusca l.) in hypercholesterolemic low-density lipoprotein receptor knockout mice.	moderate wine intake (i.e., 1-2 glasses of wine a day) is associated with a reduced risk of morbidity and mortality from cardiovascular disease. the aim of this study was to evaluate the anti-atherosclerotic effects of a nonalcoholic ethyl acetate fraction (eaf) from a south brazilian red wine obtained from vitis labrusca grapes. experiments were carried out on low-density lipoprotein (ldl) receptor knockout (ldlr⁻/⁻) mice, which were subjected to a hypercholesterolemic diet and treated with dos ...	2012	22856453
a prospective randomized double-blind trial of grape juice antioxidants in men with lower urinary tract symptoms.	many patients take alternative medications for their lower urinary tract symptoms (luts) either in addition or as a substitute for traditional therapies, despite a lack of clinical data. grapes products are hypothesized to improve bladder function due to their antioxidant and membrane-protective actions. there is increasing evidence that progression of obstructed bladder dysfunction is related to bladder ischemia, reperfusion injury and free radical damage. we prospectively studied a standardize ...	2013	22907790
molecular cloning and functional analysis of two fad2 genes from american grape (vitis labrusca l.).	the synthesis of polyunsaturated fatty acids (pufas), the most abundant fatty acids in plants, begins with a reaction catalyzed by fatty acid desaturase 2 (fad2; ec 1.3.1.35), also called microsomal oleate δ12-desaturase. since the fad2 gene was first identified in arabidopsis thaliana, fad2 research has gained wide interest as the essential enzyme for synthesizing pufa. grapes are one of the most frequently cultivated fruits in the world, with most commercial growers cultivating vitis vinifera ...	2012	22955034
colonic catabolism of dietary phenolic and polyphenolic compounds from concord grape juice.	after acute ingestion of 350 ml of concord grape juice, containing 528 μmol of (poly)phenolic compounds, by healthy volunteers, a wide array of phase i and ii metabolites were detected in the circulation and excreted in urine. ingestion of the juice by ileostomists resulted in 40% of compounds being recovered intact in ileal effluent. the current study investigated the fate of these undigested (poly)phenolic compounds on reaching the colon. this was achieved through incubation of the juice using ...	2013	22961385
efficacy of the application of a coating composed of chitosan and origanum vulgare l. essential oil to control rhizopus stolonifer and aspergillus niger in grapes (vitis labrusca l.).	this study evaluated the efficacy of the combined application of chitosan (chi) and origanum vulgare l. essential oil (ov) in the inhibition of rhizopus stolonifer urm 3728 and aspergillus niger urm 5842 on laboratory media and on grapes (vitis labrusca l.) and its influence on the physical, physicochemical and sensory characteristics of the fruits during storage (25 °c, 12 days and 12 °c, 24 days). the application of mixtures of different chi and ov concentrations (minimum inhibitory concentrat ...	2012	22986200
supercritical fluid extraction of phenolic compounds and antioxidants from grape (vitis labrusca b.) seeds.	supercritical fluid extraction (sfe) technique was applied and optimized for temperature, co₂ pressure and ethanol (modifier) concentration using orthogonal array design and response surface methodology for the extract yield, total phenols and antioxidants from grape (vitis labrusca b.) seeds. effects of extraction temperature and pressure were found to be significant for all these response variables in sfe process. optimum sfe conditions (44 ~ 46 °c temperature and 153 ~ 161 bar co₂ pressure) a ...	2012	22992888
flavan-3-ol compounds prevent pentylenetetrazol-induced oxidative damage in rats without producing mutations and genotoxicity.	seizure disorder is a chronic condition in the brain that affects approximately 50 million people worldwide. oxidative stress plays a crucial role in the pathophysiology of this disorder and can cause neuronal injury. approximately one in three treated patients suffers from seizures regardless of pharmacological intervention, which results in oxidative damage. the present study aims to investigate the possible protective effect of antioxidant-rich vitis labrusca extract on pentylenetetrazol-indu ...	2013	23262085
stilbenoid profiles of canes from vitis and muscadinia species.	we present stilbenoid profiles of canes from 16 grapevines. fifteen stilbenoids were obtained through isolation and structure identification using ms, nmr, and [α](d) or as commercial standards. an hplc-uv method for the simultaneous quantification of nine of these stilbenoids was developed and applied to canes of vitis amurensis, vitis arizonica, vitis berlandieri, vitis betulifolia, vitis cinerea, vitis × champini, vitis × doaniana, vitis labrusca, vitis candicans (syn. vitis mustangensis), vi ...	2013	23270496
endophytic fungi from vitis labrusca l. ('niagara rosada') and its potential for the biological control of fusarium oxysporum.	we investigated the diversity of endophytic fungi found on grape (vitis labrusca cv. niagara rosada) leaves collected from salesópolis, sp, brazil. the fungi were isolated and characterized by amplified ribosomal dna restriction analysis, followed by sequencing of the its1-5.8s-its2 rdna. in addition, the ability of these endophytic fungi to inhibit the grapevine pathogen fusarium oxysporum f. sp herbemontis was determined in vitro. we also observed that the climatic factors, such as temperature ...	2012	23315803
suppression of oncoprotein her-2 and dna damage after treatment with flavan-3- ol vitis labrusca extract.	hepatocellular carcinoma and breast cancer are the most prevalent cancers in the world with high morbidity and mortality. although there are effective drugs for treating advanced stages of liver and breast cancers, the prognosis for patients with liver cancer remains poor, and patients with breast cancer show considerable mortality. therefore, it is crucial to explore new therapeutic agents for the inhibition of carcinogenesis. this study examined the anti-carcinogenic effect of vitis labrusca s ...	2013	23343084