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resistance to antibiotics of bacteria involved in respiratory infections (author's transl).the present status of resistance to antibiotics of bacteria involved in respiratory infections is reviewed. schematically it can outlined as follows. streptococcus b-haemolyticus as well as pneumococcus did not change their sensitivity to penicillin, but some strains are now resistant to tetracycline. streptococcus viridans, enterococcus and h. influenzae did not change substantially their sensitivity to antibiotics. staphylococcus aureus is the bacterial species that always poses some problems ...197613744
treatment of bacteroides endocarditis with carbenicillin.a heroin addict developed acute bacterial endocarditis with streptococcus viridans and bacteroides melaninogenicus. although blood cultures became negative during penicillin g and clindamycin therapy there was little clinical response. prompt clinical improvement was achieved with intravenous carbenicillin in a dose of 40 g daily. in vitro testing supported the superiority of carbenicillin therapy in this patient.197715455
bacteriological criteria for feeding raw breast-milk to babies on neonatal units.aerobic cultures of 207 samples of drip breast-milk from seventy mothers in hospital showed that 6 (3%) were sterile and 170 (82%) contained only the commensal organisms coagulase-negative staphylococci and streptococcus viridans. 25 (15%) grew potential pathogens--staphylococcus aureus in 13 (6%); enterobacteria in 15 (7%); and group-b streptococci in 3 (2%). it is proposed that milk with commensals in any numbers may be considered for use unheated but not milk containing any potential pathogen ...197990814
[studies concerning the adequate dose of penicillin v for prevention of subacute endocarditis caused by streptococcus viridans]. 1978100843
method for studying the role of indigenous cervical flora in colonisation by neisseria gonorrhoeae.a method for quantitating cervical flora has been evaluated statistically and used to study the bacterial flora of the cervix in 14 women sexually exposed to men with gonococcal urethritis. a comparison was made between those women who subsequently became colonised with neisseria gonorrhoeae and those who did not to determine whether either total microbial populations or the different species present could be related to colonisation by n. gonorrhoeae. two control groups of healthy women, one of ...1978104769
bacterial endocarditis due to penicillin-resistant streptococcus viridans.bacterial endocarditis remains a formidable diagnostic and therapeutic problem for clinicians. streptococcus viridans still accounts for 45 to 50 per cent of all cases and between 5 to 10 per cent of all clinical isolates of streptococcus viridans from patients with bacterial endocarditis may be relatively resistant to penicillin. the case of a 9-year-old child with tetralogy of fallot and a waterston shunt who subsequently developed bacterial endocarditis due to penicillin-resistant streptococc ...1979109241
recurrent streptococcal endocarditis.a woman is described who suffered from multiple episodes of streptococcus viridans endocarditis over a decade. the possible mechanisms for recurrence are discussed and the past literature on recurrent endocarditis is reviewed. in addition, the patient developed fever and eosinophilia in response to penicillin v, while tolerating penicillin g without incident.1979112689
diffuse glomerulonephritis in rabbits with streptococcus viridans endocarditis.intravenous administration of live microorganisms to rabitts with cardiac catheters produces an experimental model of infective endocarditis. despite the development of infected valvular vegetations, positive blood cultures, splenomegaly, and focal embolic renallesions, glomerulonephritis has not been found in these animals. in the present study, acute diffuse proliferative glomerulonephritis, featuring endothelial and mesangial proliferation, capillary occlusion, and leukocytic infiltration was ...1975125360
transient bacteremia in pediatric patients after dental extraction.the incidence of bacteremia in a group of well children undergoing dental extraction of both normal and abscessed teeth was determined. blood samples were obtained from each child before and immediately after dental instrumentation and then cultured aerobically and anaerobically. eleven of 36 (30%) of the postextraction cultures were positive, and streptococcus viridans grew from all of them. bacteremia was more common after the extraction of diseased teeth, and there was no relationship between ...1976131485
abnormalities in heart membranes and myofibrils during bacterial infective cardiomyopathy in the rabbit.we studied hearts from sham-operated and uninfected catheterized rabbits as well as from rabbits at early and late stages of cardiomyopathy and failure after 3 and 6 days of infection with streptococcus viridans. no ultrastructural abnormalities or biochemical changes in membrane and myofibrillar activities were seen in 3-day uninfected hearts. in 6-day uninfected hearts there were decreased sarcolemmal m2+ atpase, na+-k+ atpase, adenylate cyclase and calcium binding, microsomal calcium binding ...1976132311
alteration in calcium metabolism in cardiac hypertrophy and failure caused by bacterial infection.left ventricular hypertrophy was seen in catheterized, uninfected rabbits, whereas contractile failure superimposed upon hypertrophy was observed in catheterized animals after injection with streptococcus viridans within six days. the infected animals showed marked changes in the ultrastructure of the left heart in comparison to the uninfected rabbits. the levels of calcium and potassium were decreased, whereas sodium was increased in both infected and uninfected hearts; however, magnesium level ...1976145639
the role of superoxide anion generation in phagocytic bactericidal activity. studies with normal and chronic granulomatous disease leukocytes.the capacity of human phagocytes to generate superoxide anion (o2-), a free radical of oxygen, and a possible role for this radical or its derivatives in the killing of phagocytized bacteria were explored using leukocytes from normal individuals and patients with chronic granulomatous disease (cgd). superoxide dismutase, which removes o2-, consistently inhibited phagocytosis-associated nitroblue tetrazolium (nbt) reduction indicating the involvement of o2- in this process. similarly, superoxide ...1975166094
[monocional immunoglobulins associated with bacterial endocarditis. two case reports (author's transl)].an iggk monoclonal gammopathy occured in two patients with streptococcus viridans bacterial endocarditis. the gammopathy has been unchanged, respectively for 32 and 21 months following its detection. the alternate physiopathologic hypothesis are argued.1979231310
penicillin-resistant "streptococcus viridans". 1979255771
bacteraemia following oesophageal dilatation and oesophago-gastroscopy.significant, but asymptomatic, bacteraemia after oesophageal dilatation with hurst's bougies for oesophageal stricture or spasm was detected in six of 11 patients. no bacteraemia was identified in ten volunteers without oesophageal pathology, who underwent passage of the same dilators. after oesophago-gastroscopy significant bacteraemia was identified in one of ten patients examined. the predominant bacterial isolates were streptococci ("streptococcus viridans" and non-haemolytic streptococcus s ...1977266890
brain abcess following dental infection.a 48-year-old woman underwent root canal treatment of the upper left lateral incisor and lower right second premolar. close to the conclusion of the endodontic treatment she complained about headaches. later on, because of aggravation of her condition, with headaches, fever, malaise, weakness, and numbness of the right limbs, she was admitted to the hospital. the disease progressed to an epileptic state, with appearance of a right hemiparesis. a brain scan and carotid arteriogram revealed the pr ...1978277859
septicemia as a complication of percutaneous liver biopsy.three cases of septicemic shock after liver biopsy are reported. escherichia coli was cultured in 2 patients and in 1 e. coli was cultured with streptococcus viridans. all 3 patients were afebrile and had normal wbc counts before the procedure. two had cholangitis and the 3rd had primary hepatoma and cirrhosis of the liver. septicemic shock should be recognized as a rare complication of liver biopsy in patients with biliary obstruction.1977321291
role of preventive antibiotics in patients undergoing cesarean section.eighty patients in labor and requiring cesarean section were selected randomly for a double-blind study using prophylactic cephalosporin and placebo. there were 26 treated patients who had no morbidity versus 13 in the control group. the reduction in endometritis was significant (p = less than .05). the most prevalent organism was streptococcus viridans, followed by escherichia coli. bacterioides organisms were recovered 17 time in 11 patients. tabulation of the fever index showed significant di ...1977333603
an immunofluorescent method for detecting antibodies against viridans streptococci in streptococcus viridans endocarditis. 1978346611
[antibacterial effect of ankerplast spray].the diffusion test yielded no satisfactory results. in the tube test, both the spray and the solvent (in a dilution of 1:4 and 1:8, respectively) proved to be bacteriostatically active against enterococci, staphylococcus aureus, escheria coli, proteus, and pseudomonas aeruginosa. these germs were killed within 30 minutes in the test for bactericidal activity, whereas the reference substance (1% phenol) required 1--2 hours, except against the last-named germ. even the copolymer exerted a bacteric ...1979377580
[bacterial endocarditis. clinical picture, treatment and course in 37 patients (author's transl)].between march 1971 and april 1976 37 patients were seen with manifest bacterial endocarditis. the main signs were high temperature and cardiac murmurs whereas other "classical" signs such as splenomegaly, anaemia, leucocytosis, and positive anti-streptolysin titres were much less frequent. in 35 cases bacteriological proof was possible. as causative organism a total of 30 gram-positive organisms (of which 15 were streptococcus viridans and 8 were staphylococcus species) and 10 gram-negative bact ...1977404127
[selective effect of propolis in the isolation of listeria monocytogenes (author's transl)].propolis is a substance produced by honeybees. it is inhibitory to some bacteria species, mainly gram-positive bacteria, but less inhibitory to listeria monocytogenes (l.m) than to the other gram-positive bacteria tested. in order to obtain selective growth of l.m. from contaminated samples, the effect of propolis in plating media and broths on various strains of bacteria was examined. table i shows the effect of increasing concentrations of propolis in tryptose-agar (ta). l.m. tolerated higher ...1977411111
infective endocarditis caused by slow-growing, fastidious, gram-negative bacteria.in a review of endocarditis caused by fastidious, slow-growing gram-negative rods, similarities in the spectrum of disease overshadow differences among cases grouped by specific organisms. cardiobacterium hominis, actinobacillus actinomycetemcomitans and haemophilus species usually seed previously damaged cardiac valves presumably during bacteremia from an upper respiratory site. the clinical presentation resembles that of streptococcus viridans endocarditis and is usually subacute or chronic. d ...1979431400
[antibiotic sensitivity of the microflora isolated in ent diseases].sensitivity of beta-hemolytic streptococci of group a, streptococcus viridans, staphylococcus aureus, epidermal staphylococci, pneumococci, proteus and ps. aeruginosa isolated in 1975-1978 from patients with tonsillitis, otitis, sinusitis and other otorhinolaryngological diseases was studied with respect to 19 antibiotics. data on comparison of the antibiotic sensitivity of the microflora isolated from the patients with otorhinolaryngological diseases in 1964-1974 and 1975-1978 are presented. it ...1979443782
bilateral endophthalmitis with streptococcus viridans endocarditis. 1979521694
comparative in vitro activity of ly 127935 (6059-s), seven cephalosporins, three aminoglycosides, carbenicillin, and ticarcillin.ly 127935 (6059-s), a new semi-synthetic beta-lactam antibiotic was tested simultaneously with 6 cephalosporins, 3 aminoglycosides, carbenicillin and ticarcillin against 398 clinical isolates of gram-negative bacilli and gram-positive cocci. many of the organisms were selected for study because of known resistance to one or more of the clinically available antibiotics tested. escherichia coli, klebsiella, serratia and providencia were susceptible to ly 127935. some resistant strains of enterobac ...1979528361
[endocarditis caused by streptococcus viridans originating in a fragment of catheter retained in the left atrium. healing by surgical removal]. 1979550770
bacterial endocarditis in england in the 1970's: a review of 70 patients.the features of 70 cases of bacterial endocarditis are reported. streptococcus viridans was the cause in 45 per cent, staphylococci in 27 per cent, and enterococci in 7 per cent. rheumatic heart disease was the predisposing factor in less than one quarter of patients and in almost half there was no obvious pre-existing cardiac disease. apart from cardiac murmurs and pyrexia, the classical features of infective endocarditis were uncommon, haematuria being observed in less than one-third. most pat ...1977594299
ticarcillin: a collaborative in vitro comparison with carbenicillin against over 9,000 clinical bacterial isolates.the minimal inhibitory concentrations of ticarcillin and carbenicillin were determined for 9,236 clinical bacterial isolates by the broth microdilution method at four participating laboratories. ticarcillin showed significantly increased activity against klebsiella pneumoniae (p less than .001), pseudomonas aeruginosa (p less than .001) and aeromonas hydrophilia (p less than .005) when compared to carbenicillin, but no signifcant differences were observed against other gram-negative organisms. t ...1977610415
antimicrobial activity in vitro of cefaclor, a new oral cephalosporin.the antimicrobial activity of cefaclor, a new orally administered cephalosporin derivative, was studied in vitro against a variety of gram-positive and gram-negative clinical isolates. both penicillin-resistant and penicillin-susceptible strains of staphylococcus aureus were susceptible to cefaclor, with mean mics of 1.44 and 0.93 microgram/ml, respectively. however, the mbc for penicillin-resistant s. aureus was higher than that for the penicillin-susceptible strains. all strains of streptococc ...1978624778
the bacteriology of chronic destructive pneumonia.thirty-four patients with chronic destructive pneumonia (cdp) were investigated bacteriologically and mycologically; specimens were obtained by transtracheal aspiration, percutaneous lung puncture, and open lung biopsy. anaerobes were isolated in the absence of aerobes in 1 case while specimens from 9 patients yielded aerobes only. in 16 patients both groups of organisms were cultured. streptococcus viridans was isolated in 12 cases and fungi in 2 cases. specimens from 8 patients were sterile on ...1978675410
[basic and clinical studies on new semisynthetic penicillin, pc-904, in pediatric field (author's transl)].pc-904 was administered to 16 pediatric patients and the following basic and clinical results were obtained. (1) pc-904 was administered 20 approximately 30 mg/kg. the serum peak level of pc-904 after drip intravenous infusion over 1 hour was 66.7 microgram/ml at 1 hour and t 1/2 of pc-904 was 67.8 minutes. pc-904 was administered 25 approximately 30 mg/kg intravenous one shot injection was 49.4 microgram/ml at 1 hour and t 1/2 of pc-904 was 52.2 minutes. (2) urinary excretion rate was about 20% ...1978691265
[the mitral valve prolapse syndrome and its complications (author's transl)].out of 1800 patients examined for valvular heart disease, 19 were found to have the mitral valve prolapse syndrome (mvps). the relevant literature is reviewed and the epidemiology and aetiology of the disease are discussed. 50% of the patients had a history of endomyocarditis. the special diagnostic value of echocardiography is emphasized. sudden death (observed in 2 young patients) and the grave complication of bacterial endocarditis (observed in 3 patients and usually caused by streptococcus v ...1978695650
[proceedings: experimental endocarditis. experimental basis and prophylaxis].a simple model has been developed for the production of bacterial endocarditis in rabbits. the principle depends on the insertion of a polyethylene catheter into the venous or arterial system so that the tip rests in the heart cavity in which endocarditis is to be established. after catheter placement, intravenous injection of any one of a variety of microorganisms regularly produces infective endocarditis. the characteristics of the infection in rabbits are similar to those observed in infectiv ...1975766173
[postoperative bacterial endocarditis after cardiac prosthesis (author's transl)].the infection of an endocardial prosthesis, either valvular or septal patch, is a frequent and dangerous post-operative complication. eleven patients having postoperative endocarditis (9 on valve prosthesis and 2 on ventricular septal patch) are the subject of this paper. six of the 7 infected "early" had gram-negative bacteria in the blood cultures, while staphylococus aureus, streptococcus viridans and klebsiella pneumoniae were responsible for 3 of the 4 "late" infections. in 2 patients, one ...1975770223
the changing character of infective endocarditis.the presentation and course of infective endocarditis is changing because there is an increasing number of resistant organisms which are causative agents. at present, resistant organisms are isolated in more than one-half of the cases; streptococcus viridans is found in only 40 percent. the increased use of antimicrobial agents, the frequent use of intravenous heroin and the increased amount of cardiac surgery have been important in increasing the number of resistant organisms and providing conv ...1975803764
[inhibition of bacterial neuraminidases by different anions (author's transl)].it was shown that neuraminidase of vibrio comma is inactivated by ca..-binding anions like citrate, edta, oxalate, phosphate or tartrate. there is, however, no inhibition of the newly described enzymes of erysipelothrix insidiosa and streptococcus viridans. pyruvate and, to a lesser extent, also citrate inactivate all the neuraminidases investigated independently of their activation by ca..ions.1975806459
rapid specific identification of group d streptococci by counterimmunoelectrophoresis.clinical isolates of group d streptococci have been examined by counterimmunoelectrophoresis (cie) to determine if this method might be of value in the rapid identification of the members of this group. group d organisms identified by classical biochemical and serologic procedures were inoculated into todd hewitt broth and incubated at 37 degrees c. after 4 hours of incubation, free group d streptococcal antigen was detected in broth cultures from 70 of 70 group d enterococcal strains. precipiti ...1976822109
[a case of subacute bacterial endocarditis treated with clindamycin-2-phosphate (author's transl)].a sixty-three years old female patient with subacute bacterial endocarditis was treated with clindamycin-2-phosphate parenterally, because she had a history of hypersensitive reaction to penicillins. she had received erythromycin, cephaloridine and cephalexin previously, but had no bacteriological response. when clindamycin-2-phosphate was given intramuscularly, the bacteremia disappeared for the first time. however, after the cessation of this treatment streptococcus viridans grew in her blood ...1977839639
effect of aspirin on thrombogenesis and on production of experimental aortic valvular streptococcus viridans endocarditis in rabbits.because thrombus formation at the site of endothelial injury has been thought to be a critical step in the pathogenesis of bacterial endocarditis, the effect of aspirin on experimental valvular thrombosis and bacterial endocarditis in rabbits was evaluated. aortic valvular injury and thrombosis were induced in aspirin-treated and control rabbits with intracardiac catheters. a subsequent inoculation of streptococcus viridans resulted in the development of infective endocarditis. rabbits were sacr ...1977843622
late-onset post-pneumonectomy empyema.nine cases of empyema developing more than three months after pneumonectomy are presented. diagnosis is difficult; with one exception, all the patients had been ill for at least three weeks and some for several months before the cause was discovered. in four, the radiological demonstration of gas in a previously opaque hemithorax led to the diagnosis. one of these had a bronchial fistula, two had oesophageal fistulae, and one had both. the remaining patients had no fistulae and the diagnoses wer ...1977867326
[present aspects of bacterial endocarditis in infants and children. observation during the years 1969-1976 (author's transl)].21 infants and children with proven bacterial endocarditis were observed at the unviersity children hospital of düsseldorf from january 1969 to december 1976. there was high incidence of cases in the infant group and again among the 6 to 8 years old children. some important aspects of the disease were characteristic for the infant group (n=5): no congenital cardiac abnormality was present, but a surgical cerebro-atrial connection in two cases of hydrocephalus and a prolonged artifical respiratio ...1977919678
infective endocarditis: a survey of cases in the south-east region of scotland, 1969-72.the incidence and characteristics of infective endocarditis were studied in a defined community over a four-year period. seventy-eight cases were found, giving an incidence of 16 cases permillion per year. the commonest presenting features were those of infection; 53% had cardiac failure and 37% evidence of emboli when first seen. twenty-three cases occurred on rheumatic heart valves, 13 on valvular prostheses, and 19 in previously normal hearts. streptococcus viridans was the commonest organism ...1976968793
right-sided endocarditis and ventricular septal defect.right-sided endocarditis occurred in a 40-year-old woman with ventricular septal defect. this association is uncommon in adults. because of the changing and variable clinical patterns of this disease, it is difficult to make a prompt diagnosis. in this case diagnosis was delayed for almost a year. the occurrence of pneumonia due to streptococcus viridans was the most important extracardiac manifestation.19761000444
abscess formation as a complication of parenteral methylphenidate abuse.case reports of five patients suffering from either skin abscesses or cellulitis following parenteral methylphenidate abuse are presented. four patients had similar lesions consisting of abscesses or cellulitis which demonstrated typical signs and symptoms of an infective process and were treated with local symptomatic therapy, incision and drainage if indicated, and systemic antibiotics. the fifth patient suffered from a circular, necrotic, nonpurulent ulcer on the dorsum of the right foot whic ...19761018375
streptococci isolated from post-extraction bacteraemias.one hundred and fifty streptococci were isolated from blood cultures taken following the extraction of teeth. the cultural, biochemical and serological characteristics of the organisms are presented and their antibiotic sensitivities discussed. it is shown that a detailed assessment of these organisms can be made rather than considering them all as streptococcus viridans.19751056797
bacterial endocarditis: a retrospective study.a retrospective study was done on patients admitted to the university of michigan hospital from 1962 to 1972 with a diagnosis of bacterial endocarditis. the findings in the group studied indicate that streptococcus viridans was the predominant causative organism, males were affected three times as often as females, erythromycin was effective against organisms of oral origin, dental procedures were not definitely established as responsible for the onset of the disease in any of the cases, and rhe ...19751057148
physiological classification of oral viridans streptococci.the human mouth harbors large numbers of a variety of greening streptococci. for many years the classification and nomenclature of these organisms have been confused, but recent studies have clarified the situation considerably. five distinct species can be distinguished among the oral streptococci s mutans, s sanguis, s mitior, s milleri, and s salivarius, and these may be identified using a simple scheme consisting of seven physiological tests. further subdivisions within these species may be ...19761060638
antagonism between chloramphenicol and penicillin in streptococcal endocarditis in rabbits.antagonism between chloramphenicol (chl) and penicillin (pch) was studied in rabbits with streptococcus viridans endocarditis. pcn alone or preceded 1 hour by chl was injected twice a day starting 6 hours or 3 days after infection. in animals treated 6 hours after infection, vegetations contained mean log colony-forming units (cfu):3.0 per gram in pcn animals and 3.7 in pcn + chl animals (p greater than 0.05) after 24 hours of treatment and 2.4 in pcn animals and 4.3 in pcn + chl animals (p grea ...19751113018
the heterogeneity of streptococcus viridans: therapeutic considerations in infective endocarditis.a 24-year-old woman with marfan's syndrome and mitral regurgitation had clinical features suggestive of infective endocarditis. the causative organism was streptococcus viridans. initial therapy with penicillin g, in a dose that should have been bactericidal and hence curative according to the results of the initial quantitative antimicrobial studies, became inadequate. the strain of s. viridans displayed considerable variation in both growth properties and antimicrobial sensitivity during the c ...19751125890
myocardial cell damage during experimental infective endocarditis.infective endocarditis was induced in 15 catheterized rabbits by a single intravenous injection of streptococcus viridans and the papillary muscles from the left ventricle were examined for histologic and ultrastructural changes at 3 and 6 days of infection. papillary muscles from 10 normal and 12 catheterized uninfected animals were used for comparison. catheterized animals, infected and uninfected, had cardiac hypertrophy and papillary muscles which showed an increase in myofiber size and some ...19751160352
clinical manifestations of splenic abscess.two patients with splenic abscess were successfully treated. in one patient, streptococcus viridans, possibly arising in a dental abscess, led to inflammatory left upper quadrant signs. an exploratory laparotomy was performed, and the spleen, being found enlarged, was removed. the other patient showed no peritoneal signs. laparotomy was done for pyrexia of unknown origin, and the removal of a normal-sized spleen was elected on the suspicion of lymphosarcoma. the spleen was abscessed, apparently ...19751172926
[use of a living culture of bacteriocinogenic strains of streptococcus viridans (streptobacterin) for the treatment of chronic tonsillitis]. 19751181767
mechanism of anaemia in experimental bacterial endocarditis.rabits with streptococcus viridans aortic valve endocarditis develop anaemia and reticulocytosis which increase with the duration of infection. mean red cell counts decreased from 6.05 +/- 0.29 x 10(6) per mul before infection to 4.10 +/- 0.18 x 10(6) per mul after 11 to 20 days of endocarditis and reticulocytes increased from 1.16 +/- 0.14 x 10(5) per mul to 4.91 +/- 0.83 x 10(5) per mul after more than 20 days of endocarditis. the anaemia could not be explained by intravascular haemolysis. ant ...19751198067
infected left atrial mass within anatomically normal heart.a case is presented with some features of subacute bacterial endocarditis and of left atrial myxoma. operative removal of a 5x3 cm tumour lying above and attached to an anatomically normal mitral valve reversed a rapidly deteriorating clinical situation. histologically the entire tumour appeared to be old thrombus, and gram-positive cocci in its superficial strata corresponded with streptococcus viridans previously isolated from blood cultures. many features, including an eight-year history of i ...19751221557
streptococcal pancarditis.an unusual association of pancarditis due to streptococcus viridans is described. the pathologic findings appear to indicate that the myocardial infection and pericarditis were blood borne.19761244263
alterations in myocardial function during bacterial infective cardiomyopathy.the status of myocardial function in rabbits subjected to cardiac catheterization and infection with streptococcus viridans was assessed at 3 and 6 days. sham-operated control animals as well as uninfected catheterized animals were used for comparison. although left heart hypertrophy and interstitial edema were evident in both uninfected and infected animals, the infected animals exhibited in addition mononuclear cell infiltration and muscle degeneration as well as lung congestion and accumulati ...19761258770
[clinical experience with amoxicillin in otorhinolaryngology (author's transl)].this paper reports the clinical trial of amoxicillin. (1) a daily dose of 750 approximately 1,000 mg of amoxicillin was orally administered for 3 approximately 12 days to 20 patients, 7 of which were with acute suppurative tympanitis, 3 with furuncle of the ear, 2 with furuncle of the nose and 8 with acute amygdalitis. as a result, amoxicillin proved remarkably effective or effective in 17 patients (85.0%). (2) amoxicillin was effective against: staphylococcus aureus in 10 of 11 patients (90.9%) ...19761263345
orbital cellulitis caused by eikenella corrodens.eikenella corrodens is a gram-negative, facultative anaerobic bacillus with specific culture and growth requirements and unusual antibacterial susceptibilities. it has only recently been recognized as a human pathogen. ocular and adnexal infections with this organism are rare especially in children. we treated two children with orbital cellulitis caused by e. corrodens. one was an 8-year-old boy; the other was an 11-year-old girl. orbital cellulitis in both patients occurred after an upper respi ...19921443020
dental caries and its determinants among recent immigrants from rural ethiopia.adults (35-45 yr old) and children (5 and 12 yr old) recently arrived in israel from rural areas in ethiopia were examined. caries levels were low: e.g. dmft = 0.31 among 12-yr-olds, and 1.27 amongst adults. the 5-yr-olds were 86.8% caries-free, while 12-yr-olds were 81.8% and adults 54% caries-free respectively. according to interview data, the diet in ethiopia had been based on local agricultural products and was almost sugar-free. the mean total count of salivary bacteria, as determined on bl ...19921464228
does primary streptococcus viridans pneumonia exist?in 4 adult black patients admitted to an urban general hospital with community-acquired pneumonia, streptococcus viridans alone was isolated from blood culture (first subculture), in the absence of any other positive microbiological finding. sputum examination by gram staining and culture in 3 cases was reported as negative. echocardiography was performed in 3 cases and was normal, without evidence of endocarditis. the clinical course of illness in the 4 patients is described. the chest radiogra ...19921465696
[surgical treatment of infected left atrial myxoma--a case report].a 22-year-old man had undergone dental therapy following an intermittent fever, and the bacteriological examination by blood culture identified streptococcus viridans. a left atrial myxoma was echocardiographically found out and the tumor was surgically resected with uneventful postoperative course. multiple foci and gram-positive cocci within the typical myxoma were revealed histopathologically. reviewing previous reports on infected cardiac myxoma, the coexistence of cardiac myxoma and a confi ...19921491206
streptococcal bacteremia in neutropenic adult patients.in order to define the circumstances of occurrence, clinical presentation and prognostic factors of streptococcal bacteremia in neutropenic patients, we retrospectively reviewed 60 cases of streptococcal bacteremia following intensive chemotherapy for acute myeloblastic leukemia (aml), acute lymphoblastic leukemia (all) or allogeneic bone marrow transplantation. causative streptococcal species included streptococcus viridans (42 cases), streptococcus faecalis (12), streptococcus pneumoniae (4) a ...19921502026
post-tonsillectomy bacteraemia.post-tonsillectomy bacteraemia is a well recognized aetiological factor in streptococcal endocarditis. prophylactic penicillin has been recommended to reduce its incidence in susceptible patients undergoing tonsillectomy. recent studies have shown a change in the microflora and an increase in the number of penicillin resistant organisms in the tonsils of patients undergoing tonsillectomy. the aim of this study has been to assess the incidence of post-tonsillectomy bacteraemia, identify the organ ...19921505085
bronchitis mimicking opportunistic lung infection in patients with human immunodeficiency virus infection/aids.purulent bronchitis was identified in 19 of 422 patients undergoing fiberoptic bronchoscopy during a 32-month period because of suspicion of an opportunistic lung infection complicating acquired immunodeficiency syndrome or human immunodeficiency virus infection. five patients had pneumocystis carinii pneumonia, but other opportunistic lung infections were excluded in the remaining 14 patients. characteristics of these 14 patients included fever (greater than 38.3 degrees c), cough, and dyspnea ...19921518586
ophthalmia neonatorum in northern norway. ii. microbiology with emphasis on chlamydia trachomatis.in a population of 1928 neonates in northern norway, ophthalmia neonatorum was diagnosed in 18.9%, including mild and self-limiting cases. sixteen out of 269 (6.0%) cultured cases were positive for chlamydia trachomatis. no gonococcal ophthalmia was seen. in neonates whose symptoms began in the maternity wards, the distribution of the isolated microorganisms (mainly staphylococcus aureus) was different from those in whom symptoms began after discharge (mainly s. aureus, staphylococcus species (c ...19921557970
capd peritonitis--initial presentation as an acute abdomen with a clear peritoneal effluent.accepted criteria for the diagnosis of peritonitis in capd include: 1. symptoms and signs of peritoneal irritation; 2. a cloudy effluent with white blood cell (wbc) count greater than 100/microliters and; 3. a positive culture. in fact, the earliest suggestive sign of peritonitis is a turbid effluent. however, symptomatology of peritoneal irritation may precede the development of a cloudy fluid. we hereby report on two capd patients with culture proven peritonitis whose initial presentation was ...19921563121
the mechanisms of preterm labor: common genital tract pathogens do not metabolize arachidonic acid to prostaglandins or to other eicosanoids.our aim was to determine the ability of pathogens commonly associated with genital tract infection and preterm labor to incorporate arachidonic acid and to metabolize it to prostaglandins or to other eicosanoids.19921595810
[a clinical study on panipenem/betamipron in chronic respiratory tract infections].panipenem/betamipron (cs-976, papm/bp), a new carbapenem antibiotic, was administered a single dose of 500 mg or 750 mg via intravenous drip infusion twice a day for treatment of chronic respiratory infection to study its clinical efficacy, bacteriological efficacy and safety. twenty nine cases were studied for the efficacy evaluation. only the safety evaluation was made in 6 cases which were judged to be unsuitable, because in some of them pneumonia and other diseases were not specified as the ...19921613969
mycotic aneurysm of the tibioperoneal trunk: case report and review of the literature.peripheral mycotic aneurysms can occur when septic emboli lodge in either the lumen or the vasa vasorum of a peripheral vessel. such aneurysms have become rare after the widespread use of aggressive antibiotic treatment for bacterial endocarditis. we report the case of a large mycotic aneurysm of the tibioperoneal trunk 18 months after an episode of streptococcus viridans bacterial endocarditis. treatment included complete resection of the aneurysmal sac with restoration of circulation to the po ...19921619727
streptococcus viridans-induced crystalline keratopathy and fungal keratitis. 19921621791
[method and procedures in bacteriological study of necrotic teeth].research was conducted of 160 radicular canals with necrotic pulp. results of different bacteriological analyses are presented. culture analyses in aerobic and anaerobic media, resulted in the isolation of staphylococcus epidermidis, streptococcus viridans and corynebacterium sp in the group studied, as the most frequent bacteria. there was no evidence of a specific germ linked with the pulp necrosis.19911659855
brain abscess following endoscopic injection sclerotherapy: report of a case.a 33-year-old male patient with hepatitis b surface antigen positive cirrhosis, received 2 courses of endoscopic injection sclerotherapy for bleeding esophageal varices. a streptococcus viridans brain abscess developed 2 weeks after the first sclerotherapy (or 1 week after the second sclerotherapy). in cirrhotic patients, an increase in pulmonary vasodilatation and pulmonary arteriovenous shunting has been well recognized. sclerosant as well as bacteria may pass through a pulmonary arteriovenous ...19911683387
prediction of rapid versus prolonged healing of infective endocarditis by monitoring vegetation size.the diagnostic value of transesophageal echocardiography in monitoring the clinical course has been evaluated in 83 patients with echocardiographic evidence of infective endocarditis. a total of 103 vegetations attached to the aortic or mitral valves were detected by use of the transesophageal approach. the patients were monitored for a mean of 74 weeks and underwent a minimum of two consecutive transesophageal echocardiographic examinations. group a included patients with increasing or remainin ...19911742034
acute purulent pericarditis in omani children.a total of eight children admitted to the royal hospital, muscat with purulent pericardial effusions were analysed. six of the cases were in children less than 2 years of age. five of the eight children had positive blood cultures: haemophilus influenzae was cultured from two patients, streptococcus pneumoniae from one patient, e. coli from one patient and streptococcus viridans from the remaining child. in three children both blood and pericardial cultures were sterile; two of these children ha ...19911784056
forty year review of bacterial endocarditis in infants and children.from 1950 through 1989 at tokyo university's department of pediatrics, 25 children were treated for bacterial endocarditis. twenty-two of these patients had previously been diagnosed as suffering from congenital heart disease. twenty one of the 25 patients had positive blood cultures. streptococcus viridans was the most common organism isolated, although the incidence of streptococcus viridans infection has decreased in the last 20 years. in present series only a few post-surgical cases with con ...19911799115
normal vaginal aerobic and anaerobic bacterial flora of the rhesus macaque (macaca mulatta).the most common bacterial species isolated from the vaginas of 37 healthy rhesus macaques were streptococcus viridans, coagulase negative staphylococcus, mobiluncus curtisii ss. curtisii, corynebacterium renale-like organisms, peptostreptococcus anaerobius, gardnerella-like organisms, and other corynebacterium species. the vaginal flora of the rhesus macaque differs from that previously reported for five other primate species. a two-year retrospective review of clinical cases of vaginitis and me ...19911803013
infectious crystalline keratopathy occurring in an eye subsequent to glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil.we present a case of infectious crystalline keratopathy occurring after 5-fluorouracil filtering surgery. the patient had discrete, branching, white crystalline lesions in the anterior corneal stroma. cultures grew streptococcus viridans, and gram-positive cocci were demonstrated in corneal tissue biopsy specimens. toxic and immunosuppressive properties of 5-fluorouracil may have participated in the pathogenesis of the infectious crystalline keratitis.19911891189
[a case of mitral stenosis developing infective endocarditis 18 months after ptmc].we presented here a case of mitral stenosis developing infective endocarditis 18 months after ptmc. a 33-year-old male was admitted to our hospital for the evaluation of mitral stenosis with signs of congestive heart failure. the use of ptmc was adequately indicated based on the data of previous cardiac catheterization and was successfully performed. the post-operative clinical course was good leaving only slight mitral regurgitation demonstrated by post-valvuloplasty lvg. about 18 months after ...19911896668
microbiology of chronic sinusitis in children.to better understand the factors involved in chronic sinusitis in childhood, we cultured the sinuses, middle meatus, and nasopharynx in 39 children requiring surgical intervention. sixty-nine percent of these patients had other medical problems, including asthma (49%) and immunologic compromise (18%). we cultured coagulase-negative staphylococcus in 18 patients, streptococcus viridans in 14 patients, normal flora in 10 patients, staphylococcus aureus in nine patients, group d streptococcus in fi ...19911910729
bacterial arthritis.in this review of the 1990 septic arthritis literature, we revisit synovial fluid leukocytosis, examine the utility of synovial fluid glucose and protein measurements, and look at the levels of two cytokines, tumor necrosis factor and interleukin-1, in infected joint fluids. we see the many faces of gonococcal arthritis and the ravages of septic arthritis when the host has rheumatoid arthritis. should we recommend antibiotic prophylaxis for the rheumatoid patient with a prosthetic joint who is u ...19911911055
spontaneous bacterial peritonitis in a healthy male caused by streptococcus viridans. 19911913382
infectious complications of pediatric liver transplantation.twenty-five pediatric orthotopic liver transplantations (olts) performed in 22 patients at sainte-justine hospital were reviewed for infections complications. one patient died within 12 hours posttransplantation and is excluded. the patients had an average age of 6.1 years (range, 1.25 to 19 years) and an average weight of 20.4 kg (range, 11 to 55 kg). two patients (9%) were cytomegalovirus (cmv) seropositive and 9 of 19 patients (48%) were epstein-barr virus (ebv) seropositive preoperatively. f ...19911919982
contact lens-related streptococcus viridans keratitis presenting as an epithelial defect. 19911929919
[antimicrobial activity of ceftazidime and its pharmacokinetics in patients with renal failure].high antimicrobial activity of ceftazidime against clinical gram-positive (except streptococcus viridans and s. faecalis) and gram-negative strains of microorganisms was shown. it was found that the drug dosing regimens required correction in cases with impaired excretion function of the kidneys. hemodialysis lowered 2-4 times the drug blood levels.19911953171
infections, preterm delivery, and perinatal death in midgestation.amniotic fluid infection results in considerable pregnancy wastage in the second and early third trimesters. in our study of 1119 perinatal autopsies amniotic sac infection was associated with death in 133 fetuses and neonates in midgestation. these cases accounted for almost 12% of all perinatal autopsies and for 20% of all perinatal autopsies in midgestation at women and infants hospital during the past decade. gram-positive organisms, especially coagulase negative staphylococcus, group b stre ...19912000473
streptococcus viridans infections in midgestation.during a 14-year period streptococcus viridans was isolated at autopsy from 18 neonates or stillborn fetuses delivered in midgestation (18-28 weeks) at women & infants' hospital in providence, rhode island. evidence of swallowed and/or aspirated, infected amniotic fluid by the fetus was found in 16 of 18 cases along with chorioamnionitis and funisitis. of the 18 cases, maternal infection was documented in 6 cases; delivery was preceded by spontaneous rupture of membranes in 9 cases and vaginal b ...19912014194
aerobic bacteria from nasal discharge of goats suffering from clinical ppr: isolation and identification.bacteriological isolation of aerobic bacteria from nasal discharge of achondroplastic west african dwarf goats showing clinical signs of peste des petits ruminants (ppr), and the laboratory procedures carried out for the identification of the isolates are described. from a total of forty nasal swabs obtained seventy five isolates were recovered. the percentage frequency of isolation of different organisms in descending order of occurrence is as follows: staphylococcus 44.0%; streptococcus 22.67% ...19912023545
[reducing vaginal flora by preoperative disinfection].in 70 gynaecological patients vaginal disinfection by povidone-iodine and chlorhexidine solution (lec) was investigated. the preoperative bacterial spectrum corresponded to the specifications in literature. only lactobacilli were found in fewer cases than expected, an effect, which was explained by the povidone-iodine sanitation of the vagina a day before the operation. in cases of disturbed lactobacilli flora, facultative pathogen species were found in high concentrations up to 10(6) cfu/ml. ge ...19912026302
[infectious endocarditis from the morphologic viewpoint: on the pathology and clinical aspects of 97 autopsy cases].in continuous autopsy material between 1978 and 1987 an infectious endocarditis was present in 97 cases of 8745 postmortem examinations. hospital acquired or iatrogenic infections were at the top of the list with 60% contribution and intravasal devices, cardiovascular or abdominal surgery acting as predominant entrance spots of the infection. in community acquired disease the portal of entry could not be ascertained in most of the cases. the spectrum of causative organisms showed staphylococcus ...19912030661
[bacteremia in febrile children].bacteremia in children under 2 years of age is not uncommon. several studies indicated that a small proportion of young children with fever who do not appear to be seriously ill may have bacteremia, and a small proportion of this subgroup may go on to develop serious illness such as meningitis. the rationale for this study was to assess both the incidence of bacteremia in febrile children in taipei area and the predictive value of the white blood cell count and degree of body temperature for bac ...19912039970
[clinical evaluation of sultamicillin in lower respiratory tract infections].clinical efficacy and safety of sultamicillin (sbtpc) in patients with lower respiratory tract infections, mainly pneumonia and bronchitis, have been evaluated in a multicenter trial by 19 institutions in the kyushu area during a period of 12 months from december 1988 to november 1989. 1. clinical evaluation was made in 132 patients and efficacy rates of sbtpc were 80.0% (28/35) for pneumonia, 78.5% (73/93) for bronchitis and 100% for the remaining 1 patient with other respiratory tract infectio ...19912041156
[neonatal conjunctivitis in a nursery and a neonatal unit].after credé prophylaxis was abandoned at our hospital in 1984 scrupulous clinical surveillance of all neonates for conjunctivitis, and bacterial cultures from purulent eye discharge, have become routine. during the two-year period 1 march 1987 to 28 february 1989, testing for chlamydia trachomatis (eia-technique) was added in all infants with clinical conjunctivitis. during the period concerned there were 332 cases of conjunctivitis among 4,520 live born infants, an incidence of 7.3%. the incide ...19912042130
endocarditis in a cow.bacterial endocarditis of the tricuspid valve was diagnosed in a cow with weight loss, reduced milk production, and intermittent fever. clinical signs of disease included jugular and mammary vein pulses, tachycardia, large cardiac silhouette, and grade-iii/v holosystolic murmur. the diagnosis was also supported by echocardiographic findings and isolation of streptococcus viridans from blood samples. the cow was treated with penicillin, furosemide, acetylsalicylic acid, heparin, and potassium chl ...19912061158
[infectious aortic endocarditis caused by streptococcus viridans mitis and acidominimus in a parenteral drug addict]. 19902094396
abnormal maxillary sinus radiographs in children: do they represent bacterial infection?thirty-three children with chronic tonsillitis and/or adenoid enlargement and without previous diagnosis of sinusitis were studied regarding the bacterial flora of their maxillary sinuses. puncture of maxillary sinus was performed at surgery (adenoidectomy and/or tonsillectomy) and aspirates were cultured. streptococcus pneumoniae was isolated from 8 of 12 (66.7%) patients whose x-rays showed completely opacified maxillary sinus. streptococcus viridans, streptococcus faecalis, and staphylococcus ...19902107515
cervical osteomyelitis due to i.v. heroin use: radiologic findings in 14 patients.we reviewed the radiographs of 14 patients who had cervical osteomyelitis and were iv heroin users. eleven were men and three were women. their age range was 33-48 years (mean, 39 years). eleven regularly used the jugular vein access, and three alternated between the jugular and femoral veins. initial radiographs of the cervical spine in 13 patients showed destruction of two or more vertebral bodies and the adjacent intervertebral disk, as well as a prevertebral soft-tissue mass. in one patient, ...19902115262
infective endocarditis: a prospective study of 60 consecutive cases.sixty cases of infective endocarditis were studied prospectively between may, 1985 and december, 1988. there were 40 males and 20 females with a mean age of 28 years. endocarditis was found on normal valves in 13 patients, on rheumatic valves in 30, on congenital lesions in 8, on prosthetic valves in 4 and on mitral valve prolapse in 5 cases. positive blood cultures were detected in 35 patients (58%). in addition bone marrow culture was positive in 1 and valves removed on surgery grew causative ...19902132422
streptococcus viridans osteomyelitis with endocarditis presenting as acute onset lower back pain.an elderly male with a history of diabetes mellitus and a recent dental procedure presented to the emergency department with acute lumbosacral pain and low grade fever. computerized tomography (ct scan) and magnetic resonance imaging (mri) yielded a presumptive diagnosis of pyogenic vertebral osteomyelitis. a diagnosis of viridans streptococcus vertebral osteomyelitis was confirmed by gallium scanning and blood culture. the literature has emphasized the occurrence of pyogenic vertebral osteomyel ...19902142706
the role of skin testing for penicillin allergy.skin testing for penicillin allergy is an imperfect predictor of severe allergic reactions. we used decision analysis to identify the types of allergy history for which skin testing should alter management. the treatment threshold, the probability of a serious allergic reaction at which point one should switch from penicillin to another antibiotic, depends on the quality of life associated with the clinical outcomes. we measured 12 physicians' attitudes toward the outcomes of treatment with peni ...19902203324
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