Publications

operational overlapping of cross-reactive and serotype-specific neutralization epitopes on vp7 of human rotavirus serotype 3.	vp7-specific neutralizing monoclonal antibodies (n-mabs) to serotype 3 human rotavirus were produced to analyze serotype 3-specific and cross-reactive neutralization epitopes on vp7. on the basis of the reactivity patterns in neutralization tests with various human and animal strains, a total of 10 n-mabs could be classified into four groups; five antibodies specific to serotype 3 were divided into two groups, and five antibodies consisted of two groups which are cross-reactive with strain 69 m ...	1991	1706592
new porcine rotavirus serotype antigenically related to human rotavirus serotype 3.	serotyping of porcine rotaviruses isolated in ma104 cells from australian piglets with diarrhea showed that two strains belonged to serotype 3 and one strain was antigenically similar to the osu strain of porcine rotavirus (serotype 5). in addition, neutralizing antibodies to human rotavirus serotype 4 (st-3 strain) were detected in serum samples from sows in one area, and so it seems probable that porcine rotaviruses of at least three serotypes occur in australia.	1988	2830302
systemic and mucosal immune responses to rhesus rotavirus vaccine mmu 18006.	thirty-four children 3 to 20 months of age ingested either 10(5), 10(4) or 10(3) plaque-forming units of rhesus rotavirus vaccine, mmu 18006, which possesses human rotavirus serotype 3 neutralization antigen. immune responses were evaluated by a plaque reduction neutralization (prn) assay to rotavirus serotypes 1, 2 and 3 and by a serum igg, igm and iga and fecal iga class-specific enzyme-linked immunosorbent assay. homotypic prn antibody seroconversions to serotype 3 rotavirus were detected in ...	1988	2839813
isolation and serotyping of porcine rotaviruses and antigenic comparison with other rotaviruses.	seven rotavirus strains were isolated in cell cultures from the intestinal contents of piglets with diarrhea. ma104 cells with pancreatin in the cell culture medium was the host system of choice for virus isolation and replication. a cell culture immunofluorescence test in which ma104 cells were used in microtiter plates was very effective for detecting and assaying rotaviruses. a plaque reduction neutralization test, cross-protection studies in gnotobiotic pigs, and electrophoresis of rotaviral ...	1984	6321541
genetic variation in the vp7 gene of human rotavirus serotype 3 (g3 type) isolated in china and japan.	sequence analysis of the vp7 gene was performed on twenty-one human isolates of serotype 3 related-rotavirus in china and japan. the five chinese isolates were found to be not similar to the 16 japanese isolates and to sa11 (simian rotavirus). the chinese isolates, especially chw2 and ch-32, were different from the major serotype 3 human isolates. au-1 and 02/92 which previously showed a wider spacing between rna segments 10 and 11 by rna polyacrylamide gel electrophoretic analysis, were more cl ...	1997	9267457
genetic variation in the vp4 and nsp4 genes of human rotavirus serotype 3 (g3 type) isolated in china and japan.	sequence analyses of the vp4 and nsp4 genes were performed on twenty human isolates of serotype g3 rotavirus obtained from china and japan. one isolate from china, chw17, possessed p[4] genotype vp4 and kun group nsp4 genes which are associated with g2. one isolate (02/92) from japan, which was shown to have a wider spacing between rna segments 10 and 11 by rna polyacrylamide gel electrophoretic analysis like au-1, possessed p[9] genotype vp4 and au-1 group nsp4 genes. the other isolates had p[8 ...	1999	10229272
bacterial expression of the major antigenic regions of porcine rotavirus vp7 induces a neutralizing immune response in mice.	the outer capsid protein of rotavirus, vp7, is a major neutralization antigen. a chimeric protein comprising escherichia coli (e. coli) outer membrane protein a (ompa) and part of porcine rotavirus vp7 containing all three antigenic regions (217 amino acids) was expressed in salmonella and e. coli as an outer-membrane associated protein. mice immunized intraperitoneally or orally, respectively, with live e. coli or salmonella cells expressing this chimeric protein produced antibodies against nat ...	1999	10418913
nucleotide sequence variation of the vp7 gene of two g3-type rotaviruses isolated from dogs.	the sequence of the vp7 gene of two rotaviruses isolated from dogs in southern italy was determined and the inferred amino acid sequence was compared with that of other rotavirus strains. there was very high nucleotide and amino acid identity between canine strain rv198/95 and other canine strains, and to the human strain hcr3a. strain rv52/96, however, was found to have about 95% identity to the g3 serotype canine strains k9, a79-10 and cu-1 and 96% identity to strain rv198/95 and to the simian ...	2001	11226570
[the predomination of rotavirus g3 serotype among children with diarrhea in lulong county in 1998].	to investigate the epidemiology of rotavirus diarrhea among children in rural population.	2001	11986693
emergence of new variant rotavirus g3 among infants and children with acute gastroenteritis in japan during 2003-2004.	a total of 402 fecal specimens from infants and children with acute gastroenteritis in five places (tokyo, maizuru, saga, sapporo, and osaka) in japan from july 2003 to june 2004 were collected and then tested for the presence of rotavirus by rt-pcr. of these, 83 were positive for rotavirus and this accounted for 20.6%. rotavirus was further characterized to g-types (vp7 genotypes) and p-types (vp4 genotypes). interestingly, an emergence of rotavirus g3 was identified with an exceptionally high ...	2007	17323824
amino acid substitutions in the vp7 protein of human rotavirus g3 isolated in china, russia, thailand, and vietnam during 2001-2004.	the distribution of rotavirus g-types in the world appears to be changing, especially with the emergence of g3 and g9 in many countries. sequence analysis of the vp7 gene was performed on the 27 human g3 rotavirus strains isolated in china, russia, thailand, and vietnam during 2001-2004. all the strains studied were clustered into the same branch of the phylogenetic tree. the comparison of the g3 deduced amino acid sequences between the studied chinese strains and the strains circulating in chin ...	2007	17705183
molecular characterization of vp4, vp6, vp7, nsp4, and nsp5/6 genes identifies an unusual g3p[10] human rotavirus strain.	an unusual strain of human rotavirus g3p[10] (cmh079/05) was detected in a stool sample of a 2-year-old child admitted to the hospital with severe diarrhea in chiang mai, thailand. analysis of the vp7 gene sequence revealed highest identities with unusual human rotavirus g3 strain cmh222 at 98.7% on the nucleotide and 99.6% on the amino acid levels. phylogenetic analysis of the vp7 sequence confirmed that the cmh079/05 strain formed a cluster with g3 rotavirus reference strains and showed the cl ...	2009	19031442
[molecular and epidemiological study on viral diarrhea among infants in lanzhou].	to study the epidemiologic characteristics of viral diarrhea in children under 5 years old in lanzhou, understand the four major virus in children of distribution.	2011	21789851
reemergence of new variant g3 rotavirus in japanese pediatric patients, 2009-2011.	the molecular epidemiology and characterization of rotaviruses obtained from non-hospitalized children with acute gastroenteritis in five different prefectures (hokkaido, saga, tokyo, osaka, and kyoto) from july 2009 to june 2011 was investigated. among 831 fecal specimens tested, rotavirus was found in 165 specimens (19.9%). the rotavirus detection rate in 2010-2011 (23.3%) was higher than those in 2009-2010 (16.0%). the highest prevalence of rotavirus was found in children aged 12 to 23 months ...	2013	23123146