Publications

TitleAbstractYear
Filter
PMID(sorted ascending)
Filter
n alpha-dimethylcoprogens. three novel trihydroxamate siderophores from pathogenic fungi.three novel siderophores have been isolated from a highly pathogenic strain of alternaria longipes (atcc 26293). the compounds are n alpha-dimethylated analogs of coprogen, neocoprogen i and isoneocoprogen i. structures of the compounds have been determined by 1h- and 13c-nmr, fast-atom-bombardment (fab) mass spectroscopy and partial hydrolysis. one of the new compounds, n alpha-dimethylcoprogen, is also produced, as the major siderophore, in another fungus, fusarium dimerum.19882978957
high-performance liquid chromatography of siderophores from fungi.a reversed-phase hplc separation of iron(iii) chelates of 16 representative fungal siderophores including ferrichromes, coprogens and triacetylfusarinine c was established in order to investigate siderophore production of fungi. for comparison purposes, the widely used bacterial siderophore ferrioxamine b was included. culture filtrates of the fungi penicillium resticulosum, fusarium dimerum, aspergillus fumigatus and neurospora crassa were quantitatively analyzed for the presence of known and u ...19882978959
[kertomycosis due to fusarium dimerum]. 19724640044
mycotoxins and fungi in wheat stored in elevators in the state of rio grande do sul, brazil.samples of wheat harvested from 1988 to 1990 and stored in elevators in the south of brazil (12 brazilian, 4 argentinian and 2 uruguayan) were analysed in 1990 for 14 mycotoxins: deoxynivalenol (don), nivalenol, diacetoxyscirpenol (das), t-2 and ht-2 toxins, t-2 triol, t-2 tetraol, aflatoxins b1, b2, g1, g2, ochratoxin a (ochra a), zearalenone and sterigmatocystin. one sample (1988 harvest) was contaminated with ochra a (0.04 microgram/g) and three other samples (1990 harvest) were contaminated ...19958522033
an exoantigen test for the rapid identification of medically significant fusarium species.the accurate identification of fusarium species can take 2-3 weeks. preliminary exoantigen studies indicate that a mature culture suspected of being a fusarium species may be immunologically identified 48 h after receipt. exoantigen extracts of 10-day-old slant cultures of fusarium chlamydosporum, fusarium moniliforme (= fusarium verticilloides), fusarium oxysporum, fusarium proliferatum and fusarium solani and partially purified reference homologous and heterologous shake culture extracts (6-we ...19958544080
in-vitro antifungal susceptibility of clinical and environmental fusarium spp. strains.the mics of amphotericin b, miconazole, ketoconazole, flucytosine, itraconazole and fluconazole for 19 isolates of fusarium oxysporum, 16 fusarium solani, seven fusarium verticilliodes, four fusarium proliferatum, four fusarium dimerum, three fusarium equiseti, and one each of the following species: fusarium graminearum, fusarium chlamydosporum, fusarium semitectum, fusarium avenaceum and fusarium subglutinans were determined by a broth microdilution method. thirty-eight of these isolates were o ...19979069536
[sensitivity to disinfectants in certain rare micromycetes].the authors investigated the effectiveness of 6 different disinfectants at recommended concentrations on strains of rare types of filamentous micromycetes: scedosporium apiospermum and exophiala dermatitidis (isolated from ophthalmomycoses), fusarium dimerum (isolates from nosocomial fungaemia) and strains of fusarium moniliforme and stachybotrys alternans (isolates from the environment and potential producers of mycotoxins). the tested strains were mostly sensitive also to an alcoholic solution ...19989611894
endocarditis due to fusarium dimerum four years after coronary artery bypass grafting. 199910028093
[keratomycosis by fusarium dimerum]. 199910217854
chemical characterization of fungal siderophores.siderophores of twenty fungi belonging to zygomycotina (5 mucorales), ascomycotina (7 aspergilli, 6 penicillia, neurospora crassa) and deuteromycotina (fusarium dimerum) were examined for their chemical nature. siderophores produced by fungi other than mucorales were all hydroxamates. mucorales produced carboxylate siderophores. catecholate type of siderophores were not detectable. hydroxamate siderophores were mostly (9 out of 15) trihydroxamates, while six were dihydroxamates. monohydroxamate ...200011233086
fatal disseminated fusarium infection in acute lymphoblastic leukaemia in complete remission.fusarium species are increasingly recognised as serious pathogens in the immunocompromised. the outcome in the context of persistent severe neutropenia has been almost universally fatal. however, there have been several case reports of successful treatment if neutrophil recovery can be achieved. this report presents the case of a fatality that occurred despite neutrophil recovery. a 67 year old man developed disseminated fusariosis during the neutropenic phase of induction chemotherapy for acute ...200111376027
successful outcome of treatment of a disseminated infection due to fusarium dimerum in a leukemia patient.we report the first case of proven disseminated infection due to fusarium dimerum associated with a favorable outcome in a patient with acute leukemia and prolonged neutropenia. the patient presented persistent fever, multiple necrotic skin lesions, and bilateral pneumopathy. f. dimerum was first isolated from three blood cultures and then from a skin biopsy and a mouth wash. microscopy of positive blood cultures showed hyphae with phialides and few curved unicellular and some rare bicellular ph ...200211880452
fusarium dimerum as a cause of human eye infections.fusarium dimerum, typically a soil fungus, was isolated from an adult male suffering from a corneal ulcer following an injury to the eye. this fungus has not been described to cause human infections in south africa and has not been recorded from soil, plant or organic material in this country. the macro- and microscopic characteristics of the isolate were found to be indistinguishable from described strains. its authenticity was confirmed by comparing it to other human isolates from the eye obta ...200212230220
fusarium dimerum infection in a stem cell transplant recipient treated successfully with voriconazole.we report the first case, to our knowledge, of a proven fusarium dimerum soft-tissue infection in a stem cell transplant recipient treated successfully with voriconazole. there is a well-documented increase in the incidence, diversity and antifungal resistance of invasive mould infections in the immunocompromised patient population. the management of these infections is changing as new, more efficacious and less toxic antifungal agents become available. we present the case of a 19-year-old femal ...200415361915
fungal catabolism of crown gall opines.this study was conducted to determine the capacities of 37 fungi to utilize various crown gall opines as their sole carbon and nitrogen source. one strain of fusarium solani, two of cylindrocarpon destructans, and six of cylindrocarpon heteronema catabolized octopine, mannopine, octopinic acid, succinamopine, or a combination of these opines. one c. heteronema and one fusarium dimerum strain grew only on succinamopine. none of the fungal isolates had the ability to grow on nopaline. the cataboli ...199016348087
in vitro interactions of antifungal agents against clinical isolates of fusarium spp.the in vitro activities of amphotericin b (amb), itraconazole (itc), voriconazole (vcz) and terbinafine (tbf) alone and in the combinations amb+vcz, tbf+itc and tbf+vcz were evaluated against 29 clinical isolates of fusarium spp. (15 fusarium solani, 7 fusarium oxysporum, 2 fusarium decemcellulare, 2 fusarium dimerum and 3 other fusarium spp.). minimum inhibitory concentrations were determined using the method of the clinical and laboratory standards institute and the interaction activity was ca ...200818054469
enniatins produced by fusarium dimerum, an endophytic fungal strain.cyclohexadepsipetides enniatin b, b1 and g were isolated from the cultivation broth of fusarium dimerum penzig, an endophyte of magnolia x soulangeana. their production was about 350 mg l(-1) after 96 h of submerged cultivation in sabouraud maltose medium. isolated enniatins inhibited growth of selected microorganisms and activity of 12-lipoxygenase with ic50 = 0.73 mg l(-1).200818717491
taxonomy and phylogeny of the fusarium dimerum species group.the morphospecies fusarium dimerum, known only from its anamorph, comprises at least 12 phylogenetically distinct species. analyses of the large subunit ribosomal dna (lsu rdna) show they are taxa of the nectriaceae (hypocreales), related to f. domesticum and form a phylogenetically distinct clade within fusarium. fusarium dimerum, for which no herbarium material could be located, is characterized by macroconidia with a single, median septum, according to the original description and illustratio ...200919271670
less-frequent fusarium species of clinical interest: correlation between morphological and molecular identification and antifungal susceptibility.forty-eight fusarium isolates morphologically identified as belonging to seven species of clinical interest (i.e., fusarium chlamydosporum, fusarium dimerum, fusarium incarnatum, fusarium napiforme, fusarium nygamai, fusarium proliferatum, and fusarium sacchari) were characterized molecularly by the analysis of the sequences of the tub region of the beta-tubulin gene. f. chlamydosporum and f. dimerum were the most genetically heterogeneous species. a high degree of correlation between the morpho ...200919321723
use of mass spectrometry to identify clinical fusarium isolates.fusarium spp. have recently emerged as significant human pathogens. identification of these species is important, both for epidemiological purposes and for patient management, but conventional identification based on morphological traits is hindered by major phenotypic polymorphism. in this study, 62 strains, or isolates, belonging to nine fusarium species were subjected to both molecular identification tef1 gene sequencing and matrix-assisted laser desorption ionization-time-of-flight (maldi-to ...200919456834
a successfully treated case of peritonitis due to fusarium dimerum.summary: fungal peritonitis is a rare but serious complication of continuous ambulatory peritoneal dialysis (capd). we report the first known case of capd peritonitis due to fusarum dimerum successfully treated with antifungals and catheter removal.201020359497
agar block smear preparation: a novel method of slide preparation for preservation of native fungal structures for microscopic examination and long-term storage.we describe a novel method of fungal slide preparation named "agar block smear preparation." a total of 510 agar block smears of 25 fungal strains obtained from culture collections, 90 qc fungal strains, and 82 clinical fungal strains from our clinical microbiology laboratory, which included a total of 137 species of yeasts, molds, and thermal dimorphic fungi, were prepared and examined. in contrast to adhesive tape preparation, agar block smears preserved the native fungal structures, such as i ...201020660221
keratomycosis complicating pterygium excision.the authors describe a case of keratomycosis that appeared after the exeresis of a pterygium. a 48-year-old patient had been referred with a red right eye associated with an abscess of the cornea along the ablation zone of the pterygium. the surgery had been performed a month beforehand. the abscess was 6 mm high and 4 mm wide. the authors instigated a treatment that included amphotericin b (0.25%) after noticing a clinical aspect evoking a fungal keratitis and finding several septate filaments ...201122034566
cutaneous fusariosis by a species of the fusarium dimerum species complex in a patient with acute myeloblastic leukemia.fusariosis is an emergent opportunistic hyalohyphomycosis produced by fungi belonging to the genus fusarium. these molds are capable of producing life-threatening diseases in immunocompromised hosts, especially in those suffering from leukemia. it has also been described in immunocompetent patients, where it usually causes non-invasive localized lesions. fusariosis in immunocompromised individuals has a high morbidity and mortality mainly because of the low sensitivity of these fungi to the anti ...201323178711
biogenic silver nanoparticles by gelidiella acerosa extract and their antifungal effects.the synthesis, characterization and application of biologically synthesized nanomaterials are an important aspect in nanotechnology. the present study deals with the synthesis of silver nanoparticles (ag-nps) using the aqueous extract of red seaweed gelidiella acerosa as the reducing agent to study the antifungal activity. the formation of ag-nps was confirmed by uv-visible spectroscopy, x-ray diffraction (xrd) pattern, scanning electron microscopy (sem) and transmission electron microscopy (tem ...201123408653
post-operative endophthalmitis due to fusarium dimerum.fungal endophthalmitis is a destructive intraocular infection resulting in poor visual prognosis. endophthalmitis due to fusarium spp has the worst visual prognosis. we report a case of a 58-year-old female patient who underwent cataract extraction and intraocular lens implantation in the right eye and presented two months after the surgery with fungal endophthalmitis. the aqueous humor culture grew fusarium dimerum. the patient was treated with intravitreal and oral voriconazole and topical pre ...201223413713
fusarium keratitis in brazil: genotyping, in vitro susceptibilities, and clinical outcomes.the purpose of this paper is to describe clinical characteristics and determine correlations between clinical outcomes and antifungal susceptibility among molecularly characterized ocular fusarium isolates in brazil.201324039389
adaptation of fusarium oxysporum and fusarium dimerum to the specific aquatic environment provided by the water systems of hospitals.members of the fusarium group were recently detected in water distribution systems of several hospitals in the world. an epidemiological investigation was conducted over 2 years in hospital buildings in dijon and nancy (france) and in non-hospital buildings in dijon. the fungi were detected only within the water distribution systems of the hospital buildings and also, but at very low concentrations, in the urban water network of nancy. all fungi were identified as fusarium oxysporum species comp ...201525792434
disseminated fusariosis and hematologic malignancies, a still devastating association. report of three new cases.fungi of the genus fusarium are primarily plant pathogens and saprobes that produce disseminated infections in immunologically deficient humans. after aspergillosis, disseminated fusariosis is the second most common cause of invasive infection by filamentous fungi in patients with hematologic malignancies or those undergoing transplants of hematopoietic progenitors.201525936697
emergence of fusarioses in a university hospital in turkey during a 20-year period.fusarium species have started appearing increasingly as the main cause of infections, particularly in immunocompromised patients. in this study, we aimed to present the first epidemiological data from turkey, analyze fusariosis cases that have been monitored in a university hospital during the past 20 years, identify the responsible fusarium species, and determine antifungal susceptibilities. a total of 47 cases of fusariosis was included in the study. fusarium isolates were identified by multil ...201525994844
phylogenetic diversity of human pathogenic fusarium and emergence of uncommon virulent species.fusarium species cause a broad spectrum of infections. however, little is known about the etiological agents to the species level. we identified fusarium species isolated from clinical specimens including those of high risk patients to better understand the species involved in the pathogenesis.201526348828
international evaluation of mic distributions and epidemiological cutoff value (ecv) definitions for fusarium species identified by molecular methods for the clsi broth microdilution method.the clsi epidemiological cutoff values (ecvs) of antifungal agents are available for various candida spp., aspergillus spp., and the mucorales. however, those categorical endpoints have not been established for fusarium spp., mostly due to the difficulties associated with collecting sufficient clsi mics for clinical isolates identified according to the currently recommended molecular dna-pcr-based identification methodologies. clsi mic distributions were established for 53 fusarium dimerum speci ...201626643334
the black yeast exophiala dermatitidis and other selected opportunistic human fungal pathogens spread from dishwashers to kitchens.we investigated the diversity and distribution of fungi in nine different sites inside 30 residential dishwashers. in total, 503 fungal strains were isolated, which belong to 10 genera and 84 species. irrespective of the sampled site, 83% of the dishwashers were positive for fungi. the most frequent opportunistic pathogenic species were exophiala dermatitidis, candida parapsilosis sensu stricto, exophiala phaeomuriformis, fusarium dimerum, and the saprochaete/magnusiomyces clade. the black yeast ...201626867131
fusarium dimerum species complex (fusarium penzigii) keratitis after corneal trauma.we report a case of a keratitis associated with a fusarium penzigii-a fusarium dimerum species complex (fdsc)-in a 81-year-old woman after a corneal trauma with a tree branch. at patient admittance, slit lamp biomicroscopy revealed an exuberant chemosis, an inferior corneal ulcer with an associated inflammatory infiltrate, a central corneal abscess, bullous keratopathy and posterior synechiae. corneal scrapes were obtained for identification of bacteria and fungi, and the patient started antibio ...201627631818
Displaying items 1 - 34 of 34