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ribosome-inactivating proteins (rna n-glycosidases) from the seeds of saponaria ocymoides and vaccaria pyramidata.from the seeds of the caryophyllaceae saponaria ocymoides and vaccaria pyramidata two proteins were purified which have the properties of the type-1 (single-chain) ribosome-inactivating proteins [reviewed by barbieri, l., battelli, m. g. & stirpe, f. (1993) ribosome-inactivating proteins from plants, biochim. biophys. acta 1154, 237-282]. the proteins have molecular masses of 30.2 kda (s. ocymoides) and 28.0 kda (v. pyramidata) and pi greater than 9.5, their n-terminal amino acid sequences are s ...19957737197
immunoconjugates made of an anti-egf receptor monoclonal antibody and type 1 ribosome-inactivating proteins from saponaria ocymoides or vaccaria pyramidata.the present paper describes two immunoconjugates consisting of an anti-epidermal growth factor receptor (egfr) monoclonal antibody (mab), named mint5, covalently linked to the type 1 ribosome-inactivating proteins (rips) ocymoidine (ocy) and pyramidatine (pyra) from saponaria ocymoides and vaccaria pyramidata respectively. both antibody and toxins are shown to retain their respective biological properties upon chemical conjugation. the immunoconjugates exert specific inhibition of egfr expressin ...19979062402
role of myzus persicae (hemiptera: aphididae) and its secondary hosts in plum pox virus propagation.plum pox virus (family potyviridae, genus potyvirus, ppv) is one of the most important viral pathogens of plants in the genus prunus, particularly prunus persica l. the role of the myzus persicae (sulzer) (hemiptera: aphididae) as a vector of ppv-m, and its role in spreading ppv-m, was investigated. ppv-m-infected peach trees were used as inoculum sources, and transmission to 15 herbaceous species commonly present in and around peach orchards was evaluated. the presence of ppv-m in secondary hos ...200717849850
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