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identification of peptide synthetase-encoding genes from filamentous fungi producing host-selective phytotoxins or analogs.race 1 of cochliobolus carbonum (cc) makes a cyclic tetrapeptide, hc-toxin, that is necessary for its virulence on certain genotypes of maize. the synthesis of hc-toxin is catalyzed by a 570-kda multifunctional enzyme, hc-toxin synthetase (hts). the gene encoding hts (hts1) is absent from other races of cc and from other species of cochliobolus. four other unrelated filamentous fungi make cyclic peptides closely related to hc-toxin, raising the possibility that the corresponding cyclic peptide s ...19958522177
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