Publications

[first report on neotoma micropus (rodentia) as a reservoir of trypanosoma cruzi in mexico].	using xenodiagnosis, two (8.0%) of 25 woodrats neotoma micropus were found infected with tripanosome parasite in vaquerias, a village in nuevo leon state, mexico. the triatomine species developing infective metacyclic trypanosomes at week 12th were triatoma pallidipennis, t. infestans and t. gerstaeckeri. experimental infections using infected dejections were successfully conducted on laboratory mice (cd1 strain) confirming the vertebrate cycle of trypanosome cruzi. the biological characterizati ...	1992	1306997
trypanosoma (herpetosoma) rangeli tejera, 1920: study of the effects of the parasite on the vector.	for evaluation of the possible pathogenicity of trypanosoma (herpetosoma) rangeli tejera, 1920 to the triatomid vector, first-stage nymphs of laboratory-bred insects were engorged upon albino mice showing average parasitemias of 2 x 10(6) and 2 x 10(5) trypanosomes/ml blood. the vector strains were: rhodnius prolixus ("new" strain), triatoma pallidipennis, and triatoma vitticeps. an "old" strain of r. prolixus (maintained 30 years in the laboratory) was also employed to check the effects of labo ...	1989	2701258
pathological effects of blastocrithidia triatomae (trypanosomatidae) on the reduviid bugs triatoma sordida, t. pallidipennis and dipetalogaster maxima after coprophagic infection.	developmental time and mortality in nymphs of the reduviid bugs triatoma sordida (stål), triatoma pallidipennis (stål) and dipetalogaster maxima (uhler) were studied in uninfected groups and in those infected with blastocrithidia triatomae cerisola et al. (trypanosomatidae). in t.sordida and t.pallidipennis, major vectors of chagas' disease in brazil and mexico respectively, infection with b.triatomae was associated with slight developmental retardations in the final instars, and increased morta ...	1988	2980188
[feeding and defecation patterns in 5th instar nymphs of 4 species of triatomines (rhodnius prolixus, triatoma pallidipennis, t. infestans and t. brasiliensis, hemiptera, reduviidae)].		1988	3071060
triabin, a highly potent exosite inhibitor of thrombin.	triabin, a new thrombin inhibitor, has been purified from the saliva of triatoma pallidipennis, a blood-sucking triatomine bug. it forms a noncovalent complex with thrombin at a molar ratio of 1:1, inhibits thrombin-induced platelet aggregation, and prolongs thrombin clotting time and activated partial thromboplastin time. however, it only minimally suppresses the amidolytic activity of thrombin, as measured by a chromogenic peptide substrate assay. it completely blocks trypsin-catalyzed cleavag ...	1995	7499380
expression of active recombinant pallidipin, a novel platelet aggregation inhibitor, in the periplasm of escherichia coli.	the platelet aggregation inhibitor pallidipin is a protein present in the saliva of the blood-sucking triatomine bug triatoma pallidipennis. expression of recombinant pallidipin in the periplasm of escherichia coli was achieved by placing its coding sequence downstream of the alkaline phosphatase (apase) or trc promoter in frame with bacterial leader peptide dna sequences derived from apase or from the periplasmic form of cyclophilin (cph). in each case the dna sequence of mature pallidipin was ...	1995	7733884
an inhibitor of collagen-induced platelet aggregation from the saliva of triatoma pallidipennis.	the saliva of triatoma pallidipennis, a blood-sucking triatomine bug (hemiptera, family reduviidae, subfamily triatominae) was found to contain a factor that specifically inhibits collagen-induced platelet aggregation. the 19-kda protein was purified to homogeneity and named pallidipin. collagen-mediated aggregation of platelets in plasma and of washed platelets was inhibited with the same efficacy. no inhibition of aggregation stimulated by other effectors (adp, thrombin, thromboxane a2 mimetic ...	1994	8106481
expression, purification and characterisation of recombinant pallidipin, a novel platelet aggregation inhibitor from the haematophageous triatomine bug triatoma pallidipennis.	pallidipin is a platelet aggregation inhibitor protein originating from the saliva of the haematophageous triatomine bug triatoma pallidipennis. its inhibitory effects are specific for collagen-induced platelet aggregation. the recombinant form of the protein was expressed in the periplasmic space of transformed escherichia coli using a vector based on the alkaline phosphatase gene promoter and leader peptide. recombinant pallidipin was purified in three chromatographic steps including cation ex ...	1996	8735814
frequency of triatomines infected with trypanosoma cruzi collected in cuernavaca city, morelos, méxico.	in order to study the frequency of infection with trypanosoma cruzi in the triatomines from cuernavaca city (morelos, mexico), 1,060 triatomines were captured with the support of the population, from september 1990 to february 1992; 1,035 were triatoma pallidipennis adults, 88% presented flagellated protozoa with morphological characteristics corresponding to trypanosoma spp. later, in the laboratory, their ability to infect nih mouse confirmed the isolates identities as trypanosoma cruzi. the o ...	1996	8986111
inhibition of thrombin-mediated cellular effects by triabin, a highly potent anion-binding exosite thrombin inhibitor.	triabin, a 17 kda protein from the saliva of the assassin bug triatoma pallidipennis is a potent thrombin inhibitor interfering with the anion-binding exosite of the enzyme. the recombinant protein, produced by the baculovirus/insect cell system, was used to study the inhibitory effect on thrombin-mediated cellular responses. the thrombin (1 nm)-stimulated aggregation of washed human platelets and the rise in cytoplasmic calcium in platelets were inhibited by triabin at nanomolar concentrations. ...	1997	9241757
structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug.	triabin, a 142-residue protein from the saliva of the blood-sucking triatomine bug triatoma pallidipennis, is a potent and selective thrombin inhibitor. its stoichiometric complex with bovine alpha-thrombin was crystallized, and its crystal structure was solved by patterson search methods and refined at 2.6-a resolution to an r value of 0.184. the analysis revealed that triabin is a compact one-domain molecule essentially consisting of an eight-stranded beta-barrel. the eight strands a to h are ...	1997	9342325
importance of triatoma pallidipennis (hemiptera: reduviidae) as a vector of trypanosoma cruzi (kinetoplastida: trypanosomatidae) in the state of morelos, mexico, and possible ecotopes.	we performed a transversal-type epidemiological study in the state of morelos, mexico, to determine the presence of triatomines, their ecotopes, and importance in transmission of trypanosoma cruzi chagas. sampling sites included domestic, peridomestic, and wild areas with collection based on the person per hour technique. we determined the entomological indices related to infestation, density, overcrowding, colonization, infection, and dispersion, which were used to calculate transmission risk. ...	1999	10337089
biology of triatoma pallidipennis stal 1945 (hemiptera: reduviidae:triatominae) under laboratory conditions.	aspects related to hatching, life time, mortality, feeding behaviour and fecundity for each stage of triatoma pallidipennis life-cycle were evaluated. the hatching rate observed for 200 eggs was 60% and the average time of hatching was 18 days. eighty nymphs (n) (40%) completed the cycle and the average time from ni to adult was 168. 7+/-11.7days. the average span in days for each stage was 18.0 for ni, 18.5 for nii, 30.0 for niii, 35.7 for niv and 50.1 for nv. the number of bloodmeals at each n ...	1999	10585665
purification, cloning, expression, and mechanism of action of a novel platelet aggregation inhibitor from the salivary gland of the blood-sucking bug, rhodnius prolixus.	rhodnius prolixus aggregation inhibitor 1 (rpai-1), a 19-kda protein isolated from the salivary gland of r. prolixus, was purified by strong cation exchange and reverse-phase high performance liquid chromatographies. based on 49 amino-terminal amino acid sequences of rpai-1, primers were produced to generate probes to screen an r. prolixus salivary gland cdna library. a phage containing the full-length clone of rpai-1 codes for a mature protein of 155 amino acids. rpai-1 shows sequence homology ...	2000	10777556
nitrophorins and related antihemostatic lipocalins from rhodnius prolixus and other blood-sucking arthropods.	recent gene sequence and crystal structure determinations of salivary proteins from several blood-sucking arthropods have revealed an unusual evolutionary relationship: many such proteins derive their functions from lipocalin protein folds. many blood-sucking arthropods have independently evolved the ability to overcome a host organism's means of preventing blood loss (called hemostasis). most blood feeders have proteins that induce vasodilation, inhibit blood coagulation, and reduce inflammatio ...	2000	11058753
[natural trypanosoma cruzi infection of triatominae bugs associated with human habitations in mexico ].	to estimate the prevalence of infection with trypanosoma cruzi in triatominae species frequently found in and around mexican dwellings, and to assess the frequency of triatominae in towns by state.	2000	11201577
sylvatic focus of american trypanosomiasis in the state of morelos, mexico.	wild vectors and reservoir hosts of trypanosoma cruzi were surveyed from february 1993 to june 1994 in ticumán (18 degrees 46'n, 99 degrees 07'w), mexico (deciduous tropical forest). direct faeces examination showed that 87% of triatoma pallidipennis hosted the parasite; t. cruzi forms were present in cultures inoculated with faeces of fifty 67% triatomine bugs and thirty cd-1 strain mice (10 d old) inoculated (peritoneum) with faeces of positive insects t. cruzi amastigotes were found in heart ...	2001	11935921
differential immunolocalization of a putative rec8p in meiotic autosomes and sex chromosomes of triatomine bugs.	hemipteran chromosomes are holocentric and show regular, special behavior at meiosis. while the autosomes pair at pachytene, have synaptonemal complexes (scs) and recombination nodules (rns) and segregate at anaphase i, the sex chromosomes do not form an sc or rns, divide equationally at anaphase i, and their chromatids segregate at anaphase ii. here we show that this behavior is shared by the x and y chromosomes of triatoma infestans and the x(1)x(2)y chromosomes of triatoma pallidipennis. as r ...	2003	12707778
development of genital plates in nymphs of triatoma pallidipennis, stål 1872, (hemiptera: reduviidae) and its application as sexing method.	searching for morphometric differences between sexes in immature forms, the development of genital plates in the exuviae of triatoma pallidipennis stål 1872 nymphs was studied. differences were found in the form and size of the 9th genital urosternite, it is larger and wider in males as compared to females. this difference is reported in several south american triatoma species. from our results it is possible to sex early stages from microscopic observation of genital plates in whole insects.	2003	14595455
[description of chagas disease in the valle de iguala, guerrero state, mexico- marco].	there are reports regarding the presence of triatomine vectors of trypanosoma cruzi, the causal agent of chagas' disease, and infected individuals on the coast and zones south of the state of guerrero, mexico. nonetheless, there are no completed reports in the valley of iguala. to know with greater precision endemic zones, seropositive individuals and their health condition, t. cruzi-infected triatomines and characteristics of dwellings were studied. seroprevalence was 1.8% by indirect elisa and ...	2003	14723049
efficacy of pyrethroid insecticides against domestic and peridomestic populations of triatoma pallidipennis and triatoma barberi (reduviidae:triatominae) vectors of chagas' disease in mexico.	a single village control trial for triatoma pallidipennis and t. barberi was conducted using three synthetic pyrethroids (bifenthrin, cyfluthrin, and deltamethrin), evaluated as residual treatments in separate sectors, with complete coverage indoors and in peridomiciliary areas. spray intervention was preceded by a preintervention entomological evaluation and household survey, followed by four postintervention evaluations at 1, 3, 6, and 12 mo of > 96% of houses. overall preintervention adjusted ...	2003	14765670
preliminary results of random amplification of polymorphic dna among triatominae of the phyllosoma complex (hemiptera, reduviidae).	in mexico, triatoma longipennis (usinger), triatoma picturata (usinger), and triatoma pallidipennis (stal), primary chagas disease vector species of the phyllosoma complex, were analyzed by randomly amplified polymorphic dna (rapd). sixteen decametric primers resolved individual profiles not identical, but partially discriminative between species. analysis based on pairwise presence/absence comparisons between the three species was performed using three primers and two outgroup species triatoma ...	2003	15049086
evaluation of risk factors for rural infestation by triatoma pallidipennis (hemiptera: triatominae), a mexican vector of chagas disease.	control of chagas disease requires control of its triatomine vectors, which requires an understanding of the determinants of infestation. twenty-seven household environmental characteristics in the town of chalcatzingo, morelos, were analyzed for association with infestation by triatoma pallidipennis, the predominant local vector. data were obtained through timed household searches for triatomines and surveys that characterized intradomicile and peridomicile environments. of the households surve ...	2004	15311472
risk factors associated with house infestation by the chagas disease vector triatoma pallidipennis in cuernavaca metropolitan area, mexico.	chagas disease caused by infection with trypanosoma cruzi chagas (kinetoplastida: trypanosomatidae) is widespread in mexico, transmitted by various triatomine bugs (hemiptera: reduviidae). the only domestic vector in cuernavaca (population 650 000) is triatoma pallidipennis (ståhl) with t. cruzi seroprevalence ranging from 1% to 9% in the resident human population. we surveyed possible risk factors for t. pallidipennis infestation at cuernavaca (altitude 1200-2200 m) on south-western slopes of t ...	2005	15958028
molecular taxonomic study of chagas disease vectors from the phyllosoma, lecticularia, and rubrofasciata complexes.	the triatiominae (hemiptera: reduviidae) are hematophagous hemipters of importance because they transmit trypanosoma cruzi, the causal agent of chagas disease. the aim of this study was to define the possible relationships between species of the phyllosoma complex (triatoma mazzottii, triatoma pallidipennis, and triatoma longipennis) and species of other complexes present in mexico that have not been previously analyzed (triatoma lecticularia and triatoma rubida). in addition, it was determined ...	2005	16103598
fine-scale predictions of distributions of chagas disease vectors in the state of guanajuato, mexico.	one of the most daunting challenges for chagas disease surveillance and control in mexico is the lack of community level data on vector distributions. although many states now have assembled representative domestic triatomine collections, only two triatomine specimens had been collected and reported previously from the state of guanajuato. field personnel from the state's secretaría de salud conducted health promotion activities in 43 of the 46 counties in the state and received donations of a t ...	2005	16465750
infestation by triatoma pallidipennis (hemiptera: reduviidae: triatominae) is associated with housing characteristics in rural mexico.	long-term control of chagas disease requires not only interruption of the human transmission cycle of trypanosoma cruzi schyzotrypanum, chagas, 1909 by controlling its domestic triatomine vectors but also surveillance to prevent reinfestation of residences from sylvatic or persistent peridomestic populations. although a number of potential risk factors for infestation have been implicated in previous studies, the explanatory power of resulting models has been low. two years after cessation of tr ...	2006	17162961
evaluation of cultures of saccharomyces cerevisae as baits for triatoma dimidiata and triatoma pallidipennis.	we tested the attraction of triatoma dimidiata and t. pallidipennis to traps baited with yeast volatiles. two traps were simultaneously presented in opposite sides of an experimental arena. one trap presented a yeast culture in sucrose solution, while the other contained sucrose solution as control. a first experimental series was done without offering a central refuge for bugs. in a second series, one shelter where the insects could hide was offered and the traps were presented afterwards. in t ...	2007	17426891
effect of ectoparasitic pimeliaphilus plumifer mites (acari: pterygosomatidae) on meccus pallidipennis (hemiptera: reduviidae) and several other chagas' disease vectors under laboratory conditions.	several biological parameters were evaluated to determine the capacity of pimeliaphilus plumifer as biological control agent of triatominae bugs. when p. plumifer and bugs of a variety of triatomine species were forced together in cages in the laboratory, the incidence of mite infestation was the following: meccus pallidipennis > m. bassolsae > triatoma rubida > m. longipennis > m. picturatus, and practically no mites were found on t. infestans and rhodnius prolixus. adults and hexapod larvae of ...	2007	17549587
importance of species of triatominae (heteroptera: reduviidae) in risk of transmission of trypanosoma cruzi in western mexico.	the epidemiological risk of infection by trypanosoma cruzi chagas in human populations of western mexico is still under study. although most vectors in this region and their vector capability are already known, new studies estimating the risk and the importance of individual triatominae species (hemiptera: reduviidae) for t. cruzi transmission are necessary. for 1 yr, every month, > 400 human dwellings and their surroundings in eight communities of two western mexico states were searched for tri ...	2008	18533443
predicting geographic and ecological distributions of triatomine species in the southern mexican state of puebla using ecological niche modeling.	we analyzed the geographic distribution using ecological niche modeling of three species of triatomines distributed in the mexican state of puebla. punctual records were gathered for a period of 5 yr of fieldwork sampling. we used the genetic algorithm for rule-set production (garp) to achieve the potential distribution of the ecological niche of triatomines. the models showed that triatoma barberi and meccus pallidipennis are sympatric and widely distributed in the central-southern part of the ...	2008	18533450
biological and genetic aspects of experimental hybrids from species of the phyllosoma complex (hemiptera: reduviidae: triatominae).	the present work is a thorough investigation of the degree of reproductive isolation between meccus mazzottii and meccus longipennis, meccus picturatus, meccus pallidipennis and meccus bassolsae, as well as between m. longipennis and m. picturatus. we examined fertility and segregation of morphological characteristics in two generations of hybrids derived from crosses between these species. the percentage of pairs with (fertile) offspring was highest in the set of crosses between m. longipennis ...	2008	18592097
risk factors associated with triatomines and its infection with trypanosoma cruzi in rural communities from the southern region of the state of mexico, mexico.	trypanosoma cruzi prevalence in triatomines and risk factors associated to the presence of the insect were studied in 990 rural houses in the southern region of the state of mexico, mexico. in each house, triatomines were collected, and information related to house construction material was obtained. t. cruzi infection was diagnosed in all triatomines. a primary screening was performed using 2 x 2 contingency tables of exposure variables. all variables with p <or= 0.20 were analyzed by logistic ...	2010	20064995
natural crossbreeding between sympatric species of the phyllosoma complex (insecta: hemiptera: reduviidae) indicate the existence of only one species with morphologic and genetic variations.	the nucleotide sequences of the cytochrome b gene and the antennal phenotypes were analyzed for the following triatomine species: triatoma longipennis, triatoma pallidipennis, and triatoma picturata, which belong to the phyllosoma complex. these species inhabit sympatric areas from talpa de allende, autlan de navarro, and teocuitatlan de corona in jalisco, mexico. molecular marker analysis showed that the sympatric individuals are the natural crossbred descendents of different individuals living ...	2010	20064999
occurrence of hybrids and laboratory evidence of fertility among three species of the phyllosoma complex (hemiptera: reduviidae) in mexico.	in seven studied communities of western mexico, triatomine specimens were sympatrically collected, some with atypical morphological characteristics in contrast to pure specimens, which were presumed to be hybrids. more than 200 specimens of meccus pallidipennis and meccus longipennis with brown-yellow markings on dorsal connexival segments were collected in ahuacapán and quitupan. in la mesa, more than 60 specimens similar to meccus picturatus in most morphological characteristics (including siz ...	2009	20140373
prevalence of trypanosoma cruzi in dogs (canis familiaris) and triatomines during 2008 in a sanitary region of the state of mexico, mexico.	american trypanosomiasis is a public health problem in latin america and southern parts of the united states. infection in triatomines (vector) and domestic dogs (reservoir host) is a good indicator of trypanosoma cruzi circulation and human risk of infection. the state of mexico, mexico, has been considered free of t. cruzi, and no detailed epidemiologic study has been conducted to assess the intricacies of the transmission cycle of the parasite in the region. such studies would enhance our und ...	2011	20575648
biological and genetic aspects of crosses between species of the genus meccus (hemiptera: reduviidae triatominae).	the degree of reproductive isolation between meccus phyllosomus and the remaining five species of the genus meccus, as well as between meccus bassolsae and meccus pallidipennis, meccus longipennis and meccus picturatus, was examined. fertility and the segregation of morphological characteristics were examined in two generations of hybrids from crosses between these species. the percentage of couples with offspring (fertile) was high in the vast majority of sets of crosses, with the exception of ...	2011	21655816
biological and genetic aspects of crosses between phylogenetically close species of mexican triatomines (hemiptera: reduviidae).	reproductive isolation between triatoma mexicana (herrich-scaeffer) and the six species of the phyllosoma complex, belonging to the genus meccus, was examined by analyzing the fertility of experimental hybrids. the percentage of couples with offspring was highest in the set of crosses between meccus phyllosomus (burmeister) and t. mexicana, and lowest in those between meccus pallidipennis (st├ñl) and meccus bassolsae (alejandre-aguilar, nogueda-torres, cort├®s-jim├®nez, jurberg, galv├úo, and car ...	2011	21661335
distribution and infection of triatomines (hemiptera: reduviidae) by trypanosoma cruzi in the state of michoac+ín, mexico.	an entomological study of triatomine species was carried out to assess their prevalence in 10 localities of the state of michoac+ín, mexico. entomological indices were calculated to estimate the risk for vector-borne transmission of trypanosoma cruzi to the human population in this area. four triatomine species (triatoma barberi, triatoma dimidiata, meccus pallidipennis and meccus longipennis) were collected from the study area. this is the first report of m. longipennis and t. dimidiata in mich ...	2011	21739032
optimization of the production of triabin, a novel thrombin inhibitor, in high five™ insect cells infected with a recombinant baculovirus.	the isolation of a new type of thrombin inhibitor, called triabin, from the saliva of the hematophagous bug triatoma pallidipennis, has recently been described. in the in vitro platelet aggregation inhibition assay triabin has a similar potency as the thrombin inhibitor hirudin now in phase iii clinical trials. however, in another in vitro assay using a low molecular weight substrate for thrombin, triabin does not inhibit thrombin completely even at 6 fold higher molar doses in comparison with h ...	1999	22359057
dimiconin, a novel coagulation inhibitor from the kissing bug, triatoma dimidiata, a vector of chagas disease.	sequence analysis of a triatoma dimidiata salivary gland cdna library resulted in the identification of two transcripts (td60 and td101) homologous to triabin, an inhibitor of thrombin in triatoma pallidipennis saliva. in the present study, a recombinant protein of td60, designated dimiconin, was expressed in escherichia coli and its activity was characterized. the resulting protein inhibited the intrinsic but not extrinsic blood coagulation pathway, suggesting that dimiconin is not a thrombin i ...	2012	22771751
ecological connectivity of trypanosoma cruzi reservoirs and triatoma pallidipennis hosts in an anthropogenic landscape with endemic chagas disease.	traditional methods for chagas disease prevention are targeted at domestic vector reduction, as well as control of transfusion and maternal-fetal transmission. population connectivity of trypanosoma cruzi-infected vectors and hosts, among sylvatic, ecotone and domestic habitats could jeopardize targeted efforts to reduce human exposure. this connectivity was evaluated in a mexican community with reports of high vector infestation, human infection, and chagas disease, surrounded by agricultural a ...	2012	23049923
bionomics of populations of meccus pallidipennis (stål), 1872 (hemiptera: reduviidae) from mexico.		2012	23181876
differences on biological attributes of three populations of meccus pallidipennis stål (hemiptera: reduviidae).	meccus pallidipennis is one of the most epidemiologically important vectors of trypanosoma cruzi to reservoir hosts in nine states of mexico. triatomines occurring in distinct locations normally adapt to local conditions. the aim of this study was to examine the biological attributes of three populations of m. pallidipennis from areas with different environmental characteristics as a factor influencing the triatomine capacity for t. cruzi transmission.	2014	24717198
development and glycoprotein composition of the perimicrovillar membrane in triatoma (meccus) pallidipennis (hemiptera: reduviidae).	hemipterans and thysanopterans (paneoptera: condylognatha) differ from other insects by having an intestinal perimicrovillar membrane (pmm) which extends from the base of the microvilli to the intestinal lumen. the development and composition of the pmm in hematophagous reduviidae depend on factors related to diet. the pmm may also allow the human parasite trypanosoma cruzi, the etiological agent of human chagas disease, to establish and develop in this insect vector. we studied the pmm developm ...	2014	25043894
lethal effects of a mexican beauveria bassiana (balsamo) strain against meccus pallidipennis (stal).	the entomopathogenic fungus beauveria bassiana (balsamo 1835) vuillemin is an effective alternative control agent against some agricultural pests and biological vectors of important diseases such as chagas disease. in this work we studied an isolate of beauveria bassiana from of the town of san antonio rayón, puebla, mexico and its entomopathogenic effects on meccus pallidipennis (stal 1872). phylogenetic analysis using molecular comparison of the its and ef1α genes, showed that the resulting cl ...	2014	25242941
distribution of constitutive heterochromatin in species of triatomines with fragmentation of sex chromosomes x.	cytogenetic analyses of triatomines are considered to be important taxonomic tools. thus, we analyzed the pattern of constitutive heterochromatin in 7 species of triatomine with fragmentation of the sex chromosome x, focusing on the cytotaxonomy of these triatomines. the species analyzed included triatoma vitticeps, triatoma melanocephala, triatoma tibiamaculata, triatoma protracta, meccus pallidipennis, panstrongylus megistus, and panstrongylus lignarius. the seminiferous tubules of the adult m ...	2014	25501239
biological characteristics of geographically isolated populations of meccus mazzottii (hemiptera: reduviidae) in southern mexico.	chagas disease, caused by trypanosoma cruzi chagas, is one of the most epidemiologically important vector-borne zoonoses in mexico. among the 32 reported triatomine species from mexico, meccus mazzottii (usinger) (hemiptera: reduviidae) is one of the most important vectors of t. cruzi in the southern part of the country. variability among populations of triatomines has been recorded for several species (meccus longipennis (usinger) and meccus pallidipennis (stal)) that are closely related to m. ...	2014	25502028
identification of g protein coupled receptors for opsines and neurohormones in rhodnius prolixus. genomic and transcriptomic analysis.	the importance of chagas disease motivated the scientific effort to obtain the complete genomic sequence of the vector species rhodnius prolixus, this information is also relevant to the understanding of triatomine biology in general. the central nervous system is the key regulator of insect physiology and behavior. neurohormones (neuropeptides and biogenic amines) are the chemical messengers involved in the regulation and integration of neuroendocrine signals. in insects, this signaling is main ...	2016	25976540
survival and immune response of the chagas vector meccus pallidipennis (hemiptera: reduviidae) against two entomopathogenic fungi, metarhizium anisopliae and isaria fumosorosea.	chagas disease is a key health problem in latin america and is caused and transmitted by trypanosoma cruzi and triatomine bugs, respectively. control of triatomines has largely relied on the use pyrethroids, which has proved to be ineffective in the long term. alternatively, the use of entomopathogenic fungi has been implemented to control triatomine bugs. these fungi are highly efficient as they induce a reduction in immune response on insects. meccus pallidipennis is the main triatomine vector ...	2016	27012246
nucleolar-persistence phenomenon during spermatogenesis in genus meccus (hemiptera, triatominae).	the triatominae subfamily consists of 150 species in 18 genera, grouped into six tribes. in cytogenetics, triatomines are important biological models because they have holocentric chromosomes and nucleolar persistence in meiosis. the phenomenon of nucleolar persistence has been described for 23 species of triatomine in three genera: triatoma, rhodnius, and panstrongylus. however, new species and genera should be analyzed to assess whether nucleolar persistence is a peculiarity of triatominae. th ...	2016	27051005
community resilience and chagas disease in a rural region of mexico.	to explore the pillars of community resilience in a region where chagas disease is endemic, with the aim of promoting participatory processes to deal with this condition from the resilience of the population.	2016	27509012
effect of the saliva from different triatomine species on the biology and immunity of tlr-4 ligand and trypanosoma cruzi-stimulated dendritic cells.	triatomines are blood-sucking vectors of trypanosoma cruzi, the causative agent of chagas disease. during feeding, triatomines surpass the skin host response through biomolecules present in their saliva. dendritic cells (dcs) play a crucial role in the induction of the protection to aggressive agents, including blood-sucking arthropods. here, we evaluated if salivary components of triatomines from different genera evade the host immunity by modulating the biology and the function of lps- or t. c ...	2016	27938380
neuropeptidomics in triatoma infestans. comparative transcriptomic analysis among triatomines.	chagas' disease, affecting up to 6-7 million people worldwide, is transmitted to humans through the feces of triatomine kissing bugs. from these, rhodnius prolixus, triatoma dimidiata, triatoma infestans and triatoma pallidipennis are important vectors distributed throughout the latin american subcontinent. resistance to pyrethroids has been developed by some triatomine populations, especially t. infestans, obstructing their control. given their role in the regulation of physiological processes, ...	2016	27993629
comparative and functional triatomine genomics reveals reductions and expansions in insecticide resistance-related gene families.	triatomine insects are vectors of trypanosoma cruzi, a protozoan parasite that is the causative agent of chagas' disease. this is a neglected disease affecting approximately 8 million people in latin america. the existence of diverse pyrethroid resistant populations of at least two species demonstrates the potential of triatomines to develop high levels of insecticide resistance. therefore, the incorporation of strategies for resistance management is a main concern for vector control programs. t ...	2017	28199333
proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid triatoma pallidipennis.	species belonging to the triatominae subfamily are commonly associated with chagas disease, as they are potential vectors of the parasite trypanosoma cruzi. however, their saliva contains a cocktail of diverse anti-hemostatic proteins that prevent blood coagulation, vasodilation and platelet aggregation of blood; components with indisputable therapeutic potential. we performed a transcriptomic and proteomic analyses of salivary glands and protein spots from 2de gels of milked saliva, respectivel ...	2017	28442446
salivary gland transcripts of the kissing bug, panstrongylus chinai, a vector of chagas disease.	the saliva of hematophagous arthropods injected during blood feeding contains potent pharmacologically active components to counteract the host hemostatic and inflammatory systems. in the present study, dominant salivary gland transcripts of panstrongylus chinai, a vector of chagas disease, were analyzed by sequencing randomly selected clones of the salivary gland cdna library. this analysis showed that 56.5% of the isolated transcripts coded for putative secreted proteins, of which 73.7% coded ...	2017	28690145
salivary lipocalin family proteins from panstrongylus chinai, a vector of chagas disease.	the dataset in this report is related to the research article with the title: "salivary gland transcripts of the kissing bug, panstrongylus chinai, a vector of chagas disease" (kato et al., 2017) [1]. lipocalin family proteins were identified as the dominant component in p. chinai saliva, and phylogenetic analysis of the salivary lipocalins resulted in the formation of five major clades. for further characterization, each clade of p. chinai lipocalin was s alignment and phylogenetic analyses tog ...	2017	29034292
comparative genomics analysis of triatomines reveals common first line and inducible immunity-related genes and the absence of imd canonical components among hemimetabolous arthropods.	insects operate complex humoral and cellular immune strategies to fend against invading microorganisms. the majority of these have been characterized in drosophila and other dipterans. information on hemipterans, including triatominae vectors of chagas disease remains incomplete and fractionated.	2018	29357911