Publications

restraining cage and method for bleeding fruit bats (rousettus aegyptiacus).		1995	502468
lunarperiodic variation of the phase-angle difference in nocturnal animals under natural zeitgeber-conditions near the equator.	several months' studies under natural illumination conditions in the vicinity of the equator show that night monkeys (aotus trivirgatus), and leaf-nosed bats (artibeus lituratus) exhibit species-specific lunarperiodic changes of the phase position of their activity rhythm to the zeitgeber rhythm (figures 1-3). these changes are closely to nightly illumination conditions. in aotus the phase-angle differences (p.a.ds) of the onset and end of the activity phase, and in artibeus the p.a.ds of the mi ...	1976	829232
the myoglobin of the fruit-bat (rousettus aegyptiacus).	the myoglobin of the fruit-bat (rousettus aegyptiacus) has been investigated. it has 153 amino acid residues. when the possible therian ancestral myoglobin is taken into consideration, the myoglobin of the fruit-bat resembles most closely that of the hedgehog.	1977	861250
structure of the penis in the fruit bat rousettus aegyptiacus (megachiroptera).		1976	1003048
the feeding pattern of the fruit bat rousettus aegyptiacus in captivity.	an electrical apparatus was designed to record continuously the feeding activity of either a colony of 30 fruit bats (rousettus aegyptiacus) or single bats in captivity. the endogenous feeding activity rhythm was synchronized by change in the external light-dark cycle. during june to august (winter), the bats consumed an average of 96 g sliced banana, equal to 76 g wet weight/100 g body weight per 24 hours or 15 g dry weight/100 g body weight per 24 hours. the feeding period began shortly after ...	1976	1019753
vitamin b12 metabolism in the fruit bat (rousettus aegyptiacus). the induction of vitamin b12 deficiency and its effect on folate levels.	1. vitamin b12 metabolism was studied in bats of the species rousettus aegyptiacus, which live on an all-fruit diet in the wild. 2. there was a wide range in values for the serum vitamin b12 concentration of newly captured bats, but bats captured in the early spring had significantly higher mean serum vitamin b12 levels than bats captured in the early autumn. 3. there was an exponential decrease in serum vitamin b12 concentration with time in captivity for bats fed on a vitamin b12-deficient, al ...	1975	1201264
methylmalonic acid metabolism and nervous-system fatty acids in cobalamin-deficient fruit bats receiving supplements of methionine, valine and isoleucine.	cobalamin neuropathy was produced in cape fruit bats (rousettus aegyptiacus) by a cobalamin-free diet combined with intermittent exposure to nitrous oxide, which inactivates cobalamin. cobalamin-deficient bats had low hepatic methylmalonyl-coa mutase holoenzyme activity, with elevated plasma and urinary methylmalonic acid levels. no significant changes could be demonstrated in the concentration of odd- or branched-chain fatty acids in the nervous system. supplementation of the cobalamin-free die ...	1991	1674859
pattern of retinotectal projection in the megachiropteran bat rousettus aegyptiacus.	the retinotopic organisation of the superior colliculus (sc) in the megachiropteran bat rousettus aegyptiacus was examined with single and multi-unit recordings and by tracing the retrograde and anterograde transport of horseradish peroxidase (hrp) between the retina and the sc. the pattern of projection of the visual field onto the sc in rousettus resembles the pattern found in most mammals. the whole of the contralateral visual field is represented and, in addition, a region of the ipsilateral ...	1991	1816270
interaction of hemoglobin with chloride and 2,3-bisphosphoglycerate. a comparative approach.	the equilibrium oxygen-binding properties of hemoglobins from reindeer (rangifer tarandus tarandus), musk ox (ovibos muschatos) and a bat (rousettus aegyptiacus) have been investigated with special reference to the effect of heterotrophic ligands such as chloride and 2,3-bisphosphoglycerate [gri(2,3)p2]. the results obtained with hemoglobins from reindeer and musk ox indicate that their low oxygen affinity and their insensitivity to gri(2,3)p2 are not only an intrinsic property of the molecule, ...	1990	2253624
cobalamin neuropathy. is s-adenosylhomocysteine toxicity a factor?	cobalamin neuropathy was produced in cape fruit bats (rousettus aegyptiacus) by a cobalamin-free diet combined with intermittent exposure to nitrous oxide, which inactivates cobalamin. there were no significant differences in s-adenosylmethionine/s-adenosylhomocysteine ratios in the central nervous system of cobalamin-deficient and cobalamin-replete bats. taken with other data there are no grounds of support for a hypothesis that cobalamin neuropathy is the result of impaired methylation, howeve ...	1990	2327959
hemoglobins from bats (myotis myotis and rousettus aegyptiacus): a possible example of molecular adaptation to different physiological requirements.	the functional properties of the hemoglobin systems from two different species of bat i.e. rousettus aegyptiacus and myotis myotis have been studied as a function of chloride, polyphosphates, ph and temperature. apart from overall similarities shared with most mammalian hemoglobins, the two systems show significant differences with respect to the effect of chloride and temperature sensitivity. these findings have been related to the different physiological needs of the two species.	1989	2590470
peripheral nerve conduction in the fruit bat with nitrous oxide induced vitamin b12 deficiency.	fruit bats rousettus aegyptiacus were depleted of vitamin b12 by exposure to the gas nitrous oxide (n2o-oxygen, 1:1 v/v) for 57-80 days. conduction velocities along the fastest fibres of the ulnar nerve, as well as the first and second peaks, were similar in control and vitamin b12 depleted animals. it is concluded that neurological impairment resulting from depletion of vitamin b12 by n2o does not involve significant impairment of ulnar nerve function in this species.	1987	2890467
haematology and iron status of the egyptian fruit bat, rousettus aegyptiacus.	1. haematological values and iron status of wild and captive fruit bats (rousettus aegyptiacus) were determined. 2. plasma iron concentrations were 175 micrograms/dl in wild males, and 286-316 micrograms/dl in captive bats. 3. total splenic stores were small (around 100 micrograms) in relation to hepatic stores (3 mg) and total haem iron (2.6 mg). 4. haemoglobin levels, red cell counts and haematocrits were unusually high and mean corpuscular volumes low. 5. lactating wild bats showed no deficit ...	1988	2900095
kasokero virus: a new human pathogen from bats (rousettus aegyptiacus) in uganda.	two virus strains were isolated by mouse inoculation from blood of rousettus aegyptiacus fruit-eating bats collected from kasokero cave in uganda. shortly after these strains were introduced in the laboratory, four additional strains were recovered from laboratory workers who had developed mild to severe illnesses presumably as a result of laboratory infection. serological studies established that these six isolates are strains of the same virus. serological tests showed also that this virus is ...	1986	3082234
tissue folates in fruit bats (rousettus aegyptiacus) with nitrous oxide-induced vitamin b12 deficiency and neurological impairment.	1. long-term exposure of the fruit bat rousettus aegyptiacus to nitrous oxide, which inactivates methylcobalamin, leads to neurological impairment and ataxia. 2. in n2o-exposed animals, liver concentrations of total folates and methyl folates decreased to less than one-fifth that of control animals. pediococcus cerevisiae-active folates were also reduced. 3. in brain, there were no changes in total or methyl folates, but p. cerevisiae-active folates were lower in n2o-exposed animals. 4. suppleme ...	1987	3120768
conservation of central nervous system glutaryl-coenzyme a dehydrogenase in fruit-eating bats with glutaric aciduria and deficient hepatic glutaryl-coenzyme a dehydrogenase.	the adult fruit-eating bat, rousettus aegypticus, excretes massive amounts of glutaric acid in the urine (20-70 mumol/mg creatinine) comparable to those of humans affected with the inherited metabolic disorder, glutaric aciduria type i. glutaric acid was quantified by sequential liquid partition chromatography and gas chromatography. oral loading with the amino acid precursors of glutaric acid, l-lysine and l-tryptophan, resulted in significant increases in glutaric acid excretion above the base ...	1988	3182847
the primary structure of the hemoglobin from the bat macrotus californicus (chiroptera).	the complete primary structure of the hemoglobin from the bat macrotus californicus (chiroptera) is presented. this hemoglobin consists of only one component. the alpha- and beta-chains were separated by reverse phase high performance liquid chromatography. the sequences of both chains were established by automatic edman degradation of the chains and the tryptic peptides, as well as of the c-terminal peptide obtained by acidic hydrolysis of the asp-pro bond in the beta-chains using the film- and ...	1987	3593539
dissociation of methionine synthetase (ec 2.1.1.13) activity and impairment of dna synthesis in fruit bats (rousettus aegyptiacus) with nitrous oxide-induced vitamin b12 deficiency.	1. the effect of methylcobalamin inactivation by the anaesthetic gas nitrous oxide on the activity of the cobalamin-dependent methionine synthetase (5-methyltetrahydrofolate homocysteine methyltransferase; ec 2.1.1.13) reaction, and on dna synthesis, in the fruit bat rousettus aegyptiacus, was examined. 2. methionine synthetase activity in the liver of bats exposed to n2o-oxygen (50:50, v/v) for 90 min/d averaged 32% of that of controls after 4 d of exposure and only 5% after 12-14 weeks of expo ...	1986	3663573
the primary structure of a mouse-eared bat (myotis velifer, chiroptera) hemoglobin.	the hemoglobin of the mouse-eared bat myotis velifer consists of one component. we present the primary structures of the alpha- and beta-globin chains which have been separated by chromatography on carboxymethyl-cellulose cm-52. the sequences have been determined by edman-degradation with the film technic or the gas phase method, using the native chains and the tryptic peptides, as well as the c-terminal prolyl-peptides obtained by acid hydrolysis of the asp-pro-bonds. compared to the correspond ...	1986	3828074
nitrous oxide induced vitamin b12 deficiency: measurement of methylation reactions in the fruit bat (rousettus aegyptiacus).	nitrous oxide induced inhibition of methionine synthetase activity has been proposed as a suitable model for the myelopathy associated with vitamin b12 deficiency. this suggests a defect in methyl group metabolism. the fruit bat has been used previously as a model for dietary induced vitamin b12 deficiency. however in the nitrous oxide treated fruit bat with neurological symptoms: no changes in [14c]ethanolamine incorporation into liver and brain phospholipids could be detected. no changes in sy ...	1986	3949064
tissue vitamin b12 levels in bat sucklings (rousettus aegyptiacus) born of vitamin b12 deficient mothers.	the weights of the brains of vitamin b12-deficient baby bats (rousettus aegyptiacus, 4-20 day old) were slightly lower than those of b12-replete infant bats. liver and kidney organ weights were similar in the two groups. brain and liver b12 levels of b12-deficient baby bats were significantly lower than those of replete controls. kidney b12 levels in deficient babies were about one quarter those of the replete babies. brain vitamin b12 levels in b12-deficient sucklings were significantly lower t ...	1986	3956153
topographic organization of facial motoneurons to individual pinna muscles in rat (rattus rattus) and bat (rousettus aegyptiacus).	the location and number of motoneurons to individual pinna muscles were determined by retrograde transport of horseradish peroxidase in rat and flying fox. the degree of ear mobility differs considerably between these species in that rats perform simpler ear movements while flying foxes move their pinnae in a sophisticated way. five pinna muscles were investigated in each species. motoneurons lay within the medial subdivision of the facial motor nucleus extending over its entire rostrocaudal len ...	1985	4056108
plasma amino acids and tissue methionine levels in fruit bats (rousettus aegyptiacus) with nitrous oxide-induced vitamin b12 deficiency.	the effect of methylcobalamin inactivation by the gas nitrous oxide on plasma amino acid and tissue methionine levels in fruit bats (rousettus aegyptiacus) was examined. animals exposed to n2o-oxygen (1:1, v/v) for 90 min daily received a fruit diet with or without methionine or betaine supplements. exposure and diets were continued for up to 17 weeks or until neurological impairment and muscular weakness was established. all the groups exposed to n2o had significantly lower liver, brain and pla ...	1985	4063293
the breeding biology of the fruit bat rousettus aegyptiacus e. geoffroy living at o degrees 22's.		1968	4386699
[the innervation of the metacarpal vein and artery of the wing of megachiroptera (rousettus aegyptiacus and pteropus giganteus)].		1971	5157432
[cholinergic innervation of digital wing vein and artery of bats (rousettus aegyptiacus)].		1969	5394034
[ionic analysis of the serum of bats (rousettus aegyptiacus) and the elaboration of a physiologic solution (c.s.i.) for the perfusion of digital alar vein].		1969	5394037
lipid composition of the brain in the cobalamin inactivated fruit bat rousettus aegyptiacus.	the fruit bat rousettus aegyptiacus, when exposed to nitrous oxide (n2o) for 8-10 weeks develops cobalamin deficiency and neurological impairment leading to ataxia and death. we report the lipid composition of cerebral tissue of control animals and impaired animals following exposure to n2o, with or without dietary folic acid supplements. there were no statistically significant differences in the concentrations of total lipids, phospholipid, glycosphingolipid, plasmalogen and cholesterol between ...	1984	6500845
effect of l-dihydroxyphenylalanine (l-dopa) and methionine on tissue s-adenosylmethionine concentrations in cobalamin-inactivated fruit bats.	the fruit bat rousettus aegyptiacus develops cobalamin deficiency when exposed to the gas nitrous oxide (n2o). the effect of dietary methionine (600 mg/kg fruit) or l-3, 4-dihydroxyphenylalanine (l-dopa, 100 mg/kg body weight daily) on brain and liver s-adenosylmethionine (adomet) concentrations, and on the neurological impairment was studied. methionine supplementation significantly delayed the onset of neurological impairment (p less than 0.01) and resulted in a 2.4 fold increase in liver adom ...	1984	6526598
tissue s-adenosylmethionine levels in fruit bats (rousettus aegyptiacus) with nitrous oxide-induced neuropathy.	the effect of cobalamin inactivation by the anaesthetic gas nitrous oxide on the concentration of s-adenosylmethionine (ado met) in brain and liver of fruit bats (rousettus aegyptiacus) was examined. test animals exposed to n2o-oxygen (50:50, v/v) developed ataxia and paralysis leading to death after an average of 9.8 weeks (n6). animals receiving pteroylmonoglutamic acid supplements in the diet became ataxic earlier (mean 8.8 weeks) while those receiving methionine supplements survived for sign ...	1983	6615764
protein profile of the myelin membrane of the fruit bat rousettus aegyptiacus.	integral membrane protein composition of the myelin membrane from normal and vitamin b12-deficient fruit bats has been compared with that of the rat. purified myelin from the fruit bat shows only one basic protein which co-migrates with the large basic protein of the rat, and thus presents a pattern similar to that of the guinea pig. no gross differences were seen in the protein patterns from normal and vitamin b12-deficient animals. bats between 4-10 days and 10-20 days post partum were also in ...	1983	6661904
lipid composition of the spinal cord in the fruit bat rousettus aegyptiacus.	spinal cords were removed from ten egyptian fruit bats rousettus aegyptiacus and the lipids analysed. the major phosphatides were choline glycerophosphatide (32.3%), ethanolamine glycerophosphatide (29.3%), serine glycerophosphatide (15.2%) and phosphatidylinositol (8.4%). sphingomyelin accounted for 13.8% of the phospholipid. glycosphingolipids amounted to 43.2 mol/100 mol lipid phosphorus, plasmalogens 32.5 mol/100 mol p and cholesterol 159.5 mol/100 mol p. the fatty acid composition of whole ...	1983	6883997
[primary structure of the hemoglobins from the egyptian fruit bat (rousettus aegyptiacus, chiroptera)].	the hemoglobin of the egyptian fruit bat (rousettus aegyptiacus) has only one component. the alpha and beta chains were separated by chromatography on cm-52 cellulose. the complete primary structures of both chains were established by automatic edman degradation of the chains and the tryptic peptides. the alignment was done by homology with alpha and beta chains of adult human hemoglobin. a comparison of these two hemoglobins shows an exchange of 14 amino acid residues in the alpha chains and of ...	1982	7141404
effect of the zeitgeber pattern on the resynchronization behaviour of dark-active mammals.	the activity of 12 egyptian fruit bats, rousettus aegyptiacus, was synchronized by 24-h illumination cycles varying in light/dark (l/d) ratios, and the effect of these ratios on the resynchronization following phase shifts of the zeitgeber signal (+8 h and -8 h) was observed. the resynchronization time in l/d:16/8 was the same as that in l/d:12/12, but that in l/d:8/16 was significantly increased. after an advance-shift, some of the bats (2 of 6 in l/d:16/8 and 6 of 12 in l/d:8/16) resynchronize ...	1982	7141748
fatty acid composition of synaptosomes from normal and cobalamin deficient bat brain.	1. synaptosomes were prepared from the brain of cobalamin deficient and cobalamin supplemented fruit bats (rousettus aegyptiacus) by a floatation method on a discontinuous sucrose gradient. 2. there were no significant differences in fatty acid composition between the deficient and supplemented bats. 3. the odd chain fatty acid 15:0 amounted to 0.2% of the total fatty acids in both groups. 4. we conclude that the fatty acids of synaptosomal lipids are not a factor in the development of neural dy ...	1982	7172626
lipid composition of the brain in the vitamin b12-deficient fruit bat (rousettus aegyptiacus) with neurological impairment.		1981	7276938
zeitgeber-schedule dependent resynchronization of circadian rhythms in nocturnal mammals (primates and chiroptera).	changing the l:d time ratio of an entraining light-dark regime leads to characteristic alterations of the resynchronization behaviour of the circadian activity rhythms in night monkeys (aotus trivirgatus) and african fruit bats (rousettus aegyptiacus) after 8 h advance and delay shifts of the ld-zeitgeber. reduced speed of re-entrainment and occurrence of antidromic resynchronization point to a lower zeitgeber strength of 24-h ld-cycles with a prolonged d-phase.	1981	7297663
the 9-kda calbindin gene of rousettus aegyptiacus: its identification and isolation from a genomic library.	a genomic library of the fruit bat (rousettus aegyptiacus) was constructed in lambda phage gt11. the titre of the library was determined to be 2 x 10(5) pfu/ml. the genomic library was amplified and the titre of the amplified library increased 300-fold to 7 x 10(7) pfu/ml. the library was screened by in situ hybridization techniques using a fragment of the mouse 9-kda calbindin cdna as a probe. screening of 10(5) plaques yielded a positive clone. three additional rounds of screening were perform ...	1994	8205389
effect of water restriction on energy and water balance and osmoregulation of the fruit bat rousettus aegyptiacus.	the energy budget, water balance and osmoregulation of the fruit bat, rousettus aegyptiacus, were studied during normal hydration and during water restriction (oven-dried apple diet). the water input and output were balanced during both normal hydration and water restriction. the kidney of the fruit bat is well adapted to handle the water load from its fruit diet by excreting large volumes (14% of the body mass per day) of dilute urine (113 +/- 25 mosmol.kg h2o-1) as well as reducing urine volum ...	1993	8254118
basal, diurnal, and stress-induced levels of glucose and glucocorticoids in captive bats.	plasma levels of glucocorticoids and glucose were measured in three species of fruit bats (chiroptera) sampled from captive populations. three species of old world bats (pteropus vampyrus, p. hypomelanus, and rousettus aegyptiacus) had plasma levels of glucose that were within the normal mammalian range (80-100 mg/dl), with no difference between males and females. all animals had detectable levels of one or both of the major glucocorticoids (cortisol and corticosterone) found in mammals. steroid ...	1993	8468542
detection of the 9-kda vitamin d-dependent calbindin gene in a fruit bat (rousettus aegyptiacus) fibroblast cell line.	1. a fibroblast cell line was established from skin and lung tissue of the fruit bat (rousettus aegyptiacus). 2. genomic dna, isolated from the fibroblast cells, was restriction digested and probed for the 9-kda calbindin gene with a 180 base-pair fragment of mouse calbindin-d9k cdna. genomic dna from rats and humans was similarly probed. 3. hybridization and thus homology was observed between the mouse probe and dna from the rat and the fruit bat, but not the human. 4. the results are discussed ...	1993	8482081
anatomical and physiological investigation of auditory input to the superior colliculus of the echolocating megachiropteran bat rousettus aegyptiacus.	the objective of this study was to investigate whether a representation of auditory space in the superior colliculus (sc) of the echolocating megachiropteran bat (rousettus aegyptiacus) exists. additionally the subcortical auditory connectivity of the sc was investigated. a total of 207 units were recorded in five awake animals while presenting acoustic stimuli (white noise, clicks, and pure tones) at different positions in space. six units responded to acoustic stimulation. three of these locat ...	1996	8951391
immunocytochemical identification of endocrine cells in the pancreas of the fruit bat, rousettus aegyptiacus.	the fruit bat, rousettus aegyptiacus, is able to absorb large amounts of glucose in very short periods of time. this ability is partly reflected by the structure of the gastrointestinal tract and pancreas. the aim of this study was to confirm preliminary histochemical studies of the bat pancreas and to identify and quantitate endocrine cells by immunocytochemical techniques in order to understand the ability of the bat to absorb these large amounts of glucose. endocrine cells were distributed in ...	1998	9593652
hearing in a megachiropteran fruit bat (rousettus aegyptiacus).	the egyptian fruit bat (rousettus aegyptiacus) is one of the few megachiropteran bats capable of echolocation. however, it uses rudimentary tongue clicks rather than laryngeally produced echo calls. we determined the audiogram of 2 bats using a conditioned avoidance procedure with fruit puree reward. at an intensity of 60 db sound pressure level, the bats' hearing extended from 2.25 khz to 64 khz, with a region of good sensitivity between 8 khz and 45 khz. a dip in sensitivity at 32 khz appears ...	1998	9861710
comparative analysis of the digestive efficiency and nitrogen and energy requirements of the phyllostomid fruit-bat (artibeus jamaicensis) and the pteropodid fruit-bat (rousettus aegyptiacus).	nitrogen (n) and energy (e) requirements of the phyllostomid fruit bat, artibeus jamaicensis, and the pteropodid fruit bat rousettus aegyptiacus, were measured in adults that were fed on four experimental diets. mean daily food intake by a. jamaicensis and r. aegyptiacus ranged from 1.1-1.6 times body mass and 0.8-1.0 times body mass, respectively. dry matter digestibility and metabolizable e coefficient were high (81.1% and 82.4%, respectively) for a. jamaicensis and (77.5% and 78.0%, respectiv ...	1999	10227185
diurnal and seasonal changes in blood composition of the free-living egyptian fruit bat (rousettus aegyptiacus).	we studied the blood profile of the free-living fruit bat (rousettus aegyptiacus) during the beginning of the activity period (around various feeding trees) and upon return to the day roost during 1994-1995. results of the present study suggest that during winter and early spring bats are characterized by a poor physical and physiological state as reflected in the blood profile, revealing elevated urea and uric acid concentrations. it was found that at the end of the resting phase, r. aegyptiacu ...	1999	10466219
sound localization in an old-world fruit bat (rousettus aegyptiacus): acuity, use of binaural cues, and relationship to vision.	the passive sound-localization acuity of egyptian fruit bats (rousettus aegyptiacus) was determined using a conditioned-avoidance procedure. the mean minimum audible angle for left-right discrimination for 3 bats was 11.6 degrees--very near the mean for terrestrial mammals. the bats also were able to localize low- and high-frequency pure tones, indicating that they can use both binaural phase-difference and binaural intensity-difference cues to localize sound. moreover, they were able to use the ...	1999	10497795
characterisation of a recently isolated lyssavirus in frugivorous zoo bats.	in july 1997 a lyssavirus was isolated in denmark from a colony of egyptian flying foxes (rousettus aegyptiacus) originating from a dutch zoo. sequencing of a 400 nucleotides coding region of the nucleoprotein and of a major part of the g-protein ectodomain encoding region of the newly isolated virus, revealed a very high similarity with european bat lyssavirus subtype 1a (ebl-1a). for characterisation of the recently isolated lyssavirus in frugivorous zoo bats, 16 frugivorous bats (rousettus ae ...	2000	11043951
presence of european bat lyssavirus rnas in apparently healthy rousettus aegyptiacus bats.	apparently healthy rousettus aegyptiacus bats were randomly chosen from a dutch colony naturally infected with european bat lyssavirus subgenotype 1a (ebl1a). these bats were euthanised three months after the first evidence of an ebl1a infection in the colony. ebl1a genomic and antigenomic rnas of the nucleoprotein gene were detected by nested reverse transcriptase pcr in 75% of the examined rousettus aegyptiacus bats. the ebl1a rnas of the nucleoprotein gene were detected mainly in brain tissue ...	2002	11892688
vitamin d metabolism in a frugivorous nocturnal mammal, the egyptian fruit bat (rousettus aegyptiacus).	the nocturnal, frugivorous egyptian fruit bat (rousettus aegyptiacus) has no obvious access to either endogenous or dietary sources of vitamin d. we hypothesized that this species under natural conditions would be vitamin d deficient and that both serum mineral concentrations and vitamin d metabolite concentrations would be low. both wild populations and captive populations appear to have an impoverished vitamin d status, as concentrations of the principle circulating metabolite, 25-hydroxyvitam ...	2003	12899852
vaccination of egyptian fruit bats (rousettus aegyptiacus) with monovalent inactivated rabies vaccine.	twenty-six captive, adult egyptian fruit bats (rousettus aegyptiacus) were tested for the presence of rabies virus neutralizing antibodies (rvna) using a rapid fluorescent focus inhibition test before and after vaccination. the bats were randomly assigned into three treatment groups: group a (n = 10) bats each received one 0.1-ml dose of monovalent inactivated rabies vaccine, group b (n = 10) bats each received two 0.1-ml doses of vaccine given 30 days apart, and group c (n = 6) bats remained un ...	2004	15193074
a pasteurella-like bacterium associated with pneumonia in captive megachiropterans.	a novel pasteurella-like organism was recovered postmortem from lung tissue of two captive wahlberg's epauleted fruit bats (epomophorus wahlbergi), with severe, unilateral pneumonia. the bats had been recently shipped and died shortly after release from a 30-day quarantine. one presented with clinical signs of anorexia and lethargy before death; the other died without prior clinical symptoms. the same pasteurella-like organism was recovered antemortem from subcutaneous abscesses in two captive l ...	2004	15193080
a vasectomy technique for egyptian fruit bats (rousettus aegyptiacus).	bats in captivity reproduce well and contraceptive techniques are needed. in initial attempts at vasectomy using a prescrotal approach, it was difficult to identify the mesoductus deferens. the technique described here uses a scrotal approach with exteriorization of the testis, followed by identification and ligation of the mesoductus deferens. nine egyptian fruit bats (rousettus aegyptiacus) underwent vasectomy for this study. no postoperative complications were seen (n = 18 testes), but some o ...	2004	15193083
animal models for glutaryl-coa dehydrogenase deficiency.	in vitro studies suggest that excitotoxic cell damage is an underlying mechanism for the acute striatal damage in glutaryl-coa dehydrogenase (gcdh) deficiency. it is believed to result from an imbalance of glutamatergic and gabaergic neurotransmission induced by the accumulating organic acids 3-hydroxyglutaric acid (3-oh-ga) and to a lesser extent glutaric acid (ga). stereotaxic administration of 3-oh-ga and ga into the rat striatum have confirmed these results, but may not truly represent the e ...	2004	15505386
echolocation signal structure in the megachiropteran bat rousettus aegyptiacus geoffroy 1810.	rousettus aegyptiacus geoffroy 1810 is a member of the only genus of megachiropteran bats to use vocal echolocation, but the structure of its brief, click-like signal is poorly described. although thought to have a simple echolocation system compared to that of microchiroptera, r. aegyptiacus is capable of good obstacle avoidance using its impulse sonar. the energy content of the signal was at least an order of magnitude smaller than in microchiropteran bats and dolphins (approximately 4 x 10(-8 ...	2004	15557022
disseminated microsporidiosis due to encephalitozoon hellem in an egyptian fruit bat (rousettus aegyptiacus).	disseminated microsporidiosis was diagnosed in an adult female egyptian fruit bat that died unexpectedly in a zoo. gross findings, which were minimal, included poor body condition, bilateral renomegaly, and mottling of the liver. histopathological lesions, which were particularly pronounced in the urogenital tract and liver, consisted primarily of inflammation associated with intracytoplasmic microsporidian spores. polymerase chain reaction -based methods were used to establish the identity of t ...	2006	16709419
ethanol and methanol as possible odor cues for egyptian fruit bats (rousettus aegyptiacus).	frugivorous bats from the old and new world use odor cues to locate and assess fruit condition. we hypothesized that egyptian fruit bats (rousettus aegyptiacus) use as odor cues those volatile compounds that increase in emission rate as fruit ripens. we examined whether the smell of fermentation products may indicate the degree of ripeness to fruit bats. we analyzed volatile compounds in the headspace (the gas space above a fruit in a closed container) of dates (phoenix dactylifera) and rusty fi ...	2006	16770719
genetic characterization of the first chiropteran papillomavirus, isolated from a basosquamous carcinoma in an egyptian fruit bat: the rousettus aegyptiacus papillomavirus type 1.	the complete genomic dna of a novel papillomavirus (pv) was isolated from a basosquamous carcinoma on the wing of an egyptian fruit bat (rousettus aegyptiacus). initial short sequences of the e1 and l1 genes of this virus were retrieved by pcr with degenerate papillomavirus-specific primers, and the entire r. aegyptiacus papillomavirus type 1 (rapv-1) dna was then amplified by long template pcr, cloned and sequenced with a transposon insertion method. the rapv-1 genome counts 7970 basepairs and ...	2006	16854536
the influence of ambient temperature and the energy and protein content of food on nitrogenous excretion in the egyptian fruit bat (rousettus aegyptiacus).	the diets of frugivorous and nectarivorous vertebrates contain much water and generally have high energy but low protein contents. therefore, we tested the prediction that to save energy under conditions of high energy demands and high water intake, frugivorous egyptian fruit bats (rousettus aegyptiacus) will increase both the absolute quantity and the proportion of ammonia in their urine. we also examined whether such changes occur when protein intake is low and water intake is high. we did thr ...	2006	16927242
between-host phylogenetic distance and feeding efficiency in hematophagous ectoparasites: rodent fleas and a bat host.	we hypothesized that a parasite exploits most effectively its principal host, less effectively a host that is phylogenetically close to its principal host, and least effectively a host that is phylogenetically distant from its principal host. we tested this hypothesis by quantifying the feeding efficiency of two flea species (parapulex chephrenis and xenopsylla ramesis) on two rodents, acomys cahirinus, the specific host of p. chephrenis, and meriones crassus, a preferred host of x. ramesis, and ...	2007	17297629
papillomavirus-associated basosquamous carcinoma in an egyptian fruit bat (rousettus aegyptiacus).	a 5-yr-old female egyptian fruit bat (rousettus aegyptiacus) had a small raised pigmented mass removed from the lateral canthus of the left eye. six additional variably sized, raised, smooth to cauliflower-like skin masses were observed randomly distributed throughout the left wing membranes. four masses were removed and diagnosed microscopically as basosquamous carcinomas and papillomas. additional masses, removed 6 mo and 1 yr later, showed bony invasion and squamous differentiation. immunohis ...	2006	17312801
iron storage disease in captive egyptian fruit bats (rousettus aegyptiacus): relationship of blood iron parameters to hepatic iron concentrations and hepatic histopathology.	this study evaluated the relationship between blood iron parameters and hepatic iron concentrations, and correlation of histologic findings with hepatic iron concentrations in a captive population of egyptian fruit bats (rousettus aegyptiacus) and island flying foxes (pteropus hypomelanus). blood samples were collected for complete blood counts, plasma biochemical profiles, serum iron concentrations, total iron-binding capacity, whole-blood lead concentrations, and plasma ferritin assays. liver ...	2005	17323561
estimating the mean abundance and feeding rate of a temporal ectoparasite in the wild: afrocimex constrictus (heteroptera: cimicidae).	the feeding frequency of blood-feeding invertebrates in the wild is largely unknown but is an important predictor for the potential of disease transmission and for estimating the effects blood feeding may have on the host population. we present a method to estimate the mean feeding frequency per individual parasite from the frequency distribution of fed and unfed individuals in the wild. we used three populations of the cimicid species, afrocimex constrictus, that parasitises the fruit bat rouse ...	2007	17362962
absorption of sugars in the egyptian fruit bat (rousettus aegyptiacus): a paradox explained.	two decades ago d. j. keegan reported results on egyptian fruit bats (rousettus aegyptiacus, megachiroptera) that were strangely at odds with the prevailing understanding of how glucose is absorbed in the mammalian intestine. keegan's in vitro tests for glucose transport against a concentration gradient and with phloridzin inhibition in fruit bat intestine were all negative, although he used several different tissue preparations and had positive control results with laboratory rats. because gluc ...	2007	17488935
distribution and morphology of cholinergic, putative catecholaminergic and serotonergic neurons in the brain of the egyptian rousette flying fox, rousettus aegyptiacus.	over the past decade much controversy has surrounded the hypothesis that the megachiroptera, or megabats, share unique neural characteristics with the primates. these observations, which include similarities in visual pathways, have suggested that the megabats are more closely related to the primates than to the other group of the chiropteran order, the microbats, and suggests a diphyletic origin of the chiroptera. to contribute data relevant to this debate, we used immunohistochemical technique ...	2007	17624722
microchip-associated leiomyosarcoma in an egyptian fruit bat (rousettus aegyptiacus).	microchips are commonly used in companion, research, and zoo animal medicine for easy, reliable, and cost-effective identification with relatively low risk of side effects. this report describes development of a metastatic leiomyosarcoma associated with a microchip in an egyptian fruit bat (rousettus aegyptiacus).	2007	17679525
marburg virus infection detected in a common african bat.	marburg and ebola viruses can cause large hemorrhagic fever (hf) outbreaks with high case fatality (80-90%) in human and great apes. identification of the natural reservoir of these viruses is one of the most important topics in this field and a fundamental key to understanding their natural history. despite the discovery of this virus family almost 40 years ago, the search for the natural reservoir of these lethal pathogens remains an enigma despite numerous ecological studies. here, we report ...	2007	17712412
lagos bat virus in kenya.	during lyssavirus surveillance, 1,221 bats of at least 30 species were collected from 25 locations in kenya. one isolate of lagos bat virus (lbv) was obtained from a dead eidolon helvum fruit bat. the virus was most similar phylogenetically to lbv isolates from senegal (1985) and from france (imported from togo or egypt; 1999), sharing with these viruses 100% nucleoprotein identity and 99.8 to 100% glycoprotein identity. this genome conservancy across space and time suggests that lbv is well ada ...	2008	18305130
ethanol concentration in food and body condition affect foraging behavior in egyptian fruit bats (rousettus aegyptiacus).	ethanol occurs in fleshy fruit as a result of sugar fermentation by both microorganisms and the plant itself; its concentration [etoh] increases as fruit ripens. at low concentrations, ethanol is a nutrient, whereas at high concentrations, it is toxic. we hypothesized that the effects of ethanol on the foraging behavior of frugivorous vertebrates depend on its concentration in food and the body condition of the forager. we predicted that ethanol stimulates food consumption when its concentration ...	2008	18320157
primate-like retinotectal decussation in an echolocating megabat, rousettus aegyptiacus.	the current study was designed to reveal the retinotectal pathway in the brain of the echolocating megabat rousettus aegyptiacus. the retinotectal pathway of other species of megabats shows the primate-like pattern of decussation in the retina; however, it has been reported that the echolocating rousettus did not share this feature. to test this prior result we injected fluorescent dextran tract tracers into the right (fluororuby) and left (fluoroemerald) superior colliculi of three adult rouset ...	2008	18367343
induction and sequencing of rousette bat interferon alpha and beta genes.	bats are considered to be natural reservoirs for several viruses of clinical importance, including rabies virus, nipah virus, and hendra virus. type i interferons (ifns) is an important part of the immune system in the defense against viral infection. to investigate the function of type i ifns upon viral infection in bats, the nucleic acid, and amino acid sequences of egyptian rousette (rousettus aegyptiacus) ifn-alpha and -beta were characterized. sequence data indicated that bat ifn-alpha cons ...	2008	18436311
sarcomatoid carcinoma in the lung of an egyptian fruit bat (rousettus aegyptiacus).	a sarcomatoid carcinoma was diagnosed in the lung of a 10-year-old captive egyptian fruit bat (rousettus aegyptiacus). both carcinomatous and sarcomatous cytologic phenotypes were identified histologically. cells of both types stained positive for pancytokeratin and s-100. stromal cells stained positively for muscle actin. no staining for vimentin was noted in either neoplastic or normal internal control tissues. to the authors' knowledge, this is the first report of a pulmonary sarcomatoid carc ...	2009	19139522
yersinia pseudotuberculosis in a closed colony of egyptian fruit bats (rousettus aegyptiacus).	an outbreak of yersinia pseudotuberculosis (yptb) occurred in a closed colony of egyptian fruit bats (rousettus aegyptiacus) and resulted in the death of seven bats over a 6-week period. an initial survey of the remaining bats revealed visceral abscessation characteristic of pseudotuberculosis in five of the 12 bats examined (41.7%), inciting depopulation of the colony. at necropsy, 70% of the 115 bats in the colony exhibited gross evidence suggestive of yptb infection, including mesenteric lymp ...	2009	19368235
cell lines from the egyptian fruit bat are permissive for modified vaccinia ankara.	bats are reservoir hosts for a spectrum of infectious diseases. some pathogens (such as hendra, nipah and marburg viruses) appear to use mainly fruit bats as reservoir. we describe designed immortalization of primary fetal cells from the egyptian fruit bat (rousettus aegyptiacus) to facilitate isolation and characterization of pathogens associated with these mammals. three cell lines with different properties were recovered and successful immortalization was confirmed by continuous cultivation f ...	2009	19540275
isolation of genetically diverse marburg viruses from egyptian fruit bats.	in july and september 2007, miners working in kitaka cave, uganda, were diagnosed with marburg hemorrhagic fever. the likely source of infection in the cave was egyptian fruit bats (rousettus aegyptiacus) based on detection of marburg virus rna in 31/611 (5.1%) bats, virus-specific antibody in bat sera, and isolation of genetically diverse virus from bat tissues. the virus isolates were collected nine months apart, demonstrating long-term virus circulation. the bat colony was estimated to be ove ...	2009	19649327
morphology and morphometry of lingual papillae in adult and newborn egyptian fruit bats (rousettus aegyptiacus).	the paper presents a comparison of the microscopic structure and morphometric traits of gustatory and mechanical lingual papillae in newborn and adult frugivorous egyptian fruit bats (rousettus aegyptiacus). all of the four types of lingual papillae found in adult animals were observed on the tongue surface in the newborn egyptian fruit bats. after the birth, the gustatory papillae (fungiform and vallate papillae) were especially well-developed, as their structural characteristics, such as morph ...	2009	19681832
large serological survey showing cocirculation of ebola and marburg viruses in gabonese bat populations, and a high seroprevalence of both viruses in rousettus aegyptiacus.	ebola and marburg viruses cause highly lethal hemorrhagic fevers in humans. recently, bats of multiple species have been identified as possible natural hosts of zaire ebolavirus (zebov) in gabon and republic of congo, and also of marburgvirus (marv) in gabon and democratic republic of congo.	2009	19785757
the microstructure of lingual papillae in the egyptian fruit bat (rousettus aegyptiacus) as observed by light microscopy and scanning electron microscopy.	the microstructure of lingual papillae on the dorsal surface of the tongue of adult egyptian fruit bats was examined by light microscopy (lm) and scanning electron microscopy (sem). this elongated tongue with a rounded apex is approximately 3 cm long -- including the 1.7cm length of the anterior free part of the tongue -- which facilitates considerable freedom of movement. the surface of the tongue has four types of lingual papillae: two types of mechanical papillae -- filiform and conical papil ...	2009	19789409
isolation of a zoonotic pathogen kluyvera ascorbata from egyptian fruit-bat rousettus aegyptiacus.	the egyptian fruit-bat rousettus aegyptiacus which had been raised at the private commercial aquarium in seoul, korea for indoor exhibition was found dead and submitted to college of veterinary medicine, seoul national university for postmortem examination. a pure bacterium of kluyvera ascorbata was isolated from the blood specimen. the isolation of k. ascorbata from fruit bat is very important, because it is the most infectious agent of the genus kluyvera that cause serious diseases to animals ...	2010	19915337
functional analysis of rousettus aegyptiacus "signal transducer and activator of transcription 1" (stat1).	bats are now known as the source of several diseases in humans, but few studies regarding immune responses and factors associated with bats have so far been reported. in this study, we focused on stat1, one of the critical components in interferon (ifn)-signaling and antiviral activity, which is often targeted by viral proteins to reduce antiviral activity and increase viral replication. we found that rousettus aegyptiacus stat1 (bat stat1) is phosphorylatable and translocates to the nucleus whe ...	2010	20067804
ethanol ingestion affects flight performance and echolocation in egyptian fruit bats.	ethanol, a potential toxin for vertebrates, is present in all fleshy fruits and its content increases as the fruit ripens. previously, we found that the marginal value of food for egyptian fruit bats, rousettus aegyptiacus, decreases when its ethanol content exceeds 1%. therefore, we hypothesized that, if ingested, food containing >1% ethanol is toxic to these bats, probably causing inebriation that will affect flight and echolocation skills. we tested this hypothesis by flying egyptian fruit ba ...	2010	20153407
gastrointestinal leiomyosarcoma in an egyptian fruit bat (rousettus aegyptiacus).	a 10-year-old female egyptian fruit bat (rousettus aegyptiacus) was evaluated for weakness and lethargy. despite clinical improvement after supportive therapy, the bat was found dead the following day. gross necropsy identified a mass associated with the duodenal wall and right renal cortex. microscopically, the duodenal and gastric tunica muscularis and serosa and the right renal cortex were effaced by interlacing bundles of neoplastic spindle cells that were diffusely and strongly positive for ...	2010	20453229
wireless recording of the calls of rousettus aegyptiacus and their reproduction using electrostatic transducers.	bats are capable of imaging their surroundings in great detail using echolocation. to apply similar methods to human engineering systems requires the capability to measure and recreate the signals used, and to understand the processing applied to returning echoes. in this work, the emitted and reflected echolocation signals of rousettus aegyptiacus are recorded while the bat is in flight, using a wireless sensor mounted on the bat. the sensor is designed to replicate the acoustic gain control wh ...	2010	20458135
lipid composition and sphingolipid fatty acids of myelin in fruit bat brain.	myelin was isolated from the brain of adult fruit bats (rousettus aegyptiacus) in a discontinuous sucrose gradient. cholesterol comprised 189.0 mol/100 mol lipid phosphorus, galactolipids 60.3 mol/100 mol phosphorus and plasmalogens 32.5 mol/100 mol phosphorus. choline and ethanolamine glycerophosphatide were present in nearly equal amounts followed by serine glycerophosphatide, sphingomyelin and inositol glycerophosphatides. the fatty acid composition of sphingomyelin and non-hydroxy cerebrosid ...	1983	20487962
fruit bats (pteropodidae) fuel their metabolism rapidly and directly with exogenous sugars.	previous studies reported that fed bats and birds mostly use recently acquired exogenous nutrients as fuel for flight, rather than endogenous fuels, such as lipids or glycogen. however, this pattern of fuel use may be a simple size-related phenomenon because, to date, only small birds and bats have been studied with respect to the origin of metabolized fuel, and because small animals carry relatively small energy reserves, considering their high mass-specific metabolic rate. we hypothesized that ...	2010	20639431
establishment of fruit bat cells (rousettus aegyptiacus) as a model system for the investigation of filoviral infection.	the fruit bat species rousettus aegyptiacus was identified as a potential reservoir for the highly pathogenic filovirus marburg virus. to establish a basis for a molecular understanding of the biology of filoviruses in the reservoir host, we have adapted a set of molecular tools for investigation of filovirus replication in a recently developed cell line, r06e, derived from the species rousettus aegyptiacus.	2010	20808767
novel adenoviruses and herpesviruses detected in bats.	samples from native hungarian or captive bats were tested by pcr for the presence of adenoviruses and herpesviruses. two novel adenoviruses from a common noctule (nyctalus noctula) and a greater horseshoe (rhinolophus ferrum-equinum) bat were detected. in captive egyptian fruit bats (rousettus aegyptiacus), dna from two novel herpesviruses was demonstrated. phylogenetic analysis facilitated provisional taxonomic placement of the newly detected viruses. such analysis and the existence of unique, ...	2011	20813566
[bats and other reservoir hosts of filoviridae. danger of epidemic on the african continent?--a deductive literature analysis].	ebola and marburg virus, forming the filoviridae family, cause hemorrhagic fever in countries of sub-saharan africa. these viral diseases are characterized by a sudden epidemic occurrence as well as a high lethality. even though a reservoir host has not been approved yet, literature indicates the order of bats (chiroptera) as a potential reservoir host. significant references lead to a delineation of a hypothetical ecosystem of filoviridae including chiroptera. igg-specific ebola-zaire antibodie ...	2010	20924703
bartonella spp. in bats, kenya.	we report the presence and diversity of bartonella spp. in bats of 13 insectivorous and frugivorous species collected from various locations across kenya. bartonella isolates were obtained from 23 eidolon helvum, 22 rousettus aegyptiacus, 4 coleura afra, 7 triaenops persicus, 1 hipposideros commersoni, and 49 miniopterus spp. bats. sequence analysis of the citrate synthase gene from the obtained isolates showed a wide assortment of bartonella strains. phylogenetically, isolates clustered in spec ...	2010	21122216
[bats in israel: is there a reason for medical concern?].	bats (classified in the order chiroptera) are the most abundant and widely distributed species of mammals in the world. they occupy a variety of ecosystems and are known for their ecological importance as seed dispersers, pollinators and insectivores. the order chiroptera, containing 33 known species, is the largest mammalian order in israel bats are homothermous, can fly for long distances, have long life spans and are very often highly gregarious. these traits make them important reservoir hos ...	2010	21341436
click-based echolocation in bats: not so primitive after all.	echolocating bats of the genus rousettus produce click sonar signals, using their tongue (lingual echolocation). these signals are often considered rudimentary and are believed to enable only crude performance. however, the main argument supporting this belief, namely the click's reported long duration, was recently shown to be an artifact. in fact, the sonar clicks of rousettus bats are extremely short, ~50-100 μs, similar to dolphin vocalizations. here, we present a comparison between the sona ...	2011	21465138
the possible roles of ethanol in the relationship between plants and frugivores: first experiments with egyptian fruit bats.	in this paper we discuss how yeast, fungi ubiquitously present in sugar-rich fruit, can influence the interaction between frugivores and fleshy-fruited plants via ethanol. we suggest that plants, the seeds of which are mostly dispersed by vertebrates, exploit the ethanol from alcoholic fermentation by yeast in their seed dispersal strategy. moderate consumption of ethanol, i.e., at concentrations close to those in naturally ripening fruit, by frugivores may have beneficial short- and long-term e ...	2004	21676712
effects of ethanol on food consumption and skin temperature in the egyptian fruit bat (rousettus aegyptiacus).	since mammalian frugivores generally choose to eat ripe fruit in which ethanol concentration ([etoh]) increases as the fruit ripens, we asked whether ethanol acts as an appetitive stimulant in the egyptian fruit bat, rousettus aegyptiacus, and also studied the effects of ethanol on their skin temperature (t(s)). we hypothesized that the responses of fruit bats to dietary ethanol are concentration dependent and tested the predictions that the bats' response is positive, i.e., they eat more when [ ...	2011	21705791
large-scale navigational map in a mammal.	navigation, the ability to reach desired goal locations, is critical for animals and humans. animal navigation has been studied extensively in birds, insects, and some marine vertebrates and invertebrates, yet we are still far from elucidating the underlying mechanisms in other taxonomic groups, especially mammals. here we report a systematic study of the mechanisms of long-range mammalian navigation. high-resolution global positioning system tracking of bats was conducted here, which revealed h ...	2011	21844350
Commerson's leaf-nosed bat (Hipposideros commersoni) is the likely reservoir of Shimoni bat virus.	In this study we attempted to identify whether Commerson's leaf-nosed bat (Hipposideros commersoni) is the reservoir of Shimoni bat virus (SHIBV), which was isolated from a bat of this species in 2009. An alternative explanation is that the isolation of SHIBV from H. commersoni was a result of spill-over infection from other species, particularly from the Egyptian fruit bats (Rousettus aegyptiacus), which frequently sympatrically roost with H. commersoni and are known as the reservoir of the phy ...	2011	21867415
is marburg virus enzootic in gabon?	marburg virus (marv) nucleic acid was detected in rousettus aegyptiacus bats in 2005 and 2006 in the midwest and southeast of gabon. in this study we used marv-specific real-time reverse-transcription polymerase chain reaction (rt-pcr) and marv-specific nested rt-pcr assay to screen 1257 bats caught during july 2009, december 2009, and june 2010 in 3 caves situated in northern gabon. nine specimens tested positive by the real-time assay, with cycle threshold values ranging from 35 to 39, of whic ...	2011	21987754
effects of host diet and thermal state on feeding performance of the flea xenopsylla ramesis.	we examined feeding performance of the flea xenopsylla ramesis on three different hosts: its natural, granivorous, rodent host, sundevall's jird (meriones crassus); the frugivorous egyptian fruit bat (rousettus aegyptiacus); and an insectivorous bat, kuhl's pipistrelle (pipistrellus kuhlii). because these fleas are not known to occur on bats, we hypothesized that the fleas' feeding performance (i.e. feeding and digestion rates) would be higher when feeding on their natural host than on either of ...	2012	22496278
authentication of the r06e fruit bat cell line.	fruit bats and insectivorous bats are believed to provide a natural reservoir for a wide variety of infectious diseases. several lines of evidence, including the successful isolation of infectious viruses, indicate that marburg virus and ravn virus have found a major reservoir in colonies of the egyptian rousette (rousettus aegyptiacus). to facilitate molecular studies on virus-reservoir host interactions and isolation of viruses from environmental samples, we established cell lines from primary ...	2012	22754654
identification of a novel bat papillomavirus by metagenomics.	the discovery of novel viruses in animals expands our knowledge of viral diversity and potentially emerging zoonoses. high-throughput sequencing (hts) technology gives millions or even billions of sequence reads per run, allowing a comprehensive survey of the genetic content within a sample without prior nucleic acid amplification. in this study, we screened 156 rectal swab samples from apparently healthy bats (n = 96), pigs (n = 9), cattles (n = 9), stray dogs (n = 11), stray cats (n = 11) and ...	2012	22937142
outbreak of yersiniosis in egyptian rousette bats (rousettus aegyptiacus) caused by yersinia pseudotuberculosis serotype 4b.	this report describes an outbreak of yersiniosis in egyptian rousette bats (rousettus aegyptiacus) caused by yersinia pseudotuberculosis serotype 4b. twelve of 61 bats died between november and december 2008 or in may 2009. the bats often displayed multiple yellow-white nodules in the spleen and liver. microscopically, these consisted of focal necrosis accompanied by inflammatory cell infiltration and colonies of gram-negative bacilli. the bacterial colonies were identified immunohistochemically ...	2013	22980777