Publications

survey of helminth infections in maine dairy cattle.	the survey was done to determine the incidence and seasonal prevalence of the gastrointestinal helminths infecting maine dairy cattle. approximately equal groups of calves, heifers, and cows from 13 dairy farms, managerially and geographically representative of dairying in the state, were sampled at regular 2-month intervals over the period of a year. on the basis of fecal egg counts and identification of cultured larvae, the following results were obtained: of the 94 adult cows, 78 heifers, and ...	1975	127538
[relation between endocrinology and psychiatry. some recent developments].	relations between endocrinology and psychiatry are developing in two main directions: behavioural effects of hormones. after the effects of peripheral hormones, recent works are concerned with a.c.t.h. and antidiuretic hormone (which interfere with memory process) and with hypothalamic peptides (which might have psychotropic properties, independant of their endocrine regulation function). -correlations between psychiatric syndroms and endocrine disorders. in some mentally depressed patients, dis ...	2003	165466
a simple, specific, radioisotopic assay for 5'-nucleotidase.		2003	165748
transcription of simian virus 40 dna by escherichia coli rna polymerase: synthesis of a dna-rna hybrid and discrete rnas under restrictive transcription conditions.		1975	167179
[can one make up for lack of humaneness?].		2003	187843
a linkage study of rabbit serum high density lipoprotein (hdl) allotypes.	close linkage between the two allotypic systems of rabbit serum high density lipoprotein (hdl), hl 1 and r 67, has been confidently excluded, the recombination fraction being at least 0-20. no suggestion of linkage between either hdl allotype and the immunoglobulin allotypes a1a2a3/b4b9, or the red blood cell system (rbc) adf was obtained. close linkage was confidently excluded for the hl 1-adf, hl 1-a1a2a3, r 67-adf, r 67-a1a2a3, r 67-b4b9, a1a2a3-b4b9, and b4b9-adf relationships.	1977	194985
the equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver.	the reversibility of the nad+ kinase reaction was established, and the kinetic parameters of the rate equation in the reverse direction were determined. the equilibrium constant of the reaction was determined by using the purified pigeon liver enzyme and radioactively labelled nicotinamide nucleotides. the relationship between kinetic parameters of the forward and reverse reactions is in reasonable agreement with the measured equilibrium constant. as expected from the proposed mechanism of actio ...	2003	201249
comparison of interferon action in interferon resistant and sensitive l1210 cells.	translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...	1978	212514
mucin-producing atypical bronchial carcinoid.	in a case of atypical mucin-producing bronchial carcinoid in a 40-year-old man covert metastases were present at the time of lobectomy and were revealed at necropsy--a feature highlighting the malignant potential of the atypical carcinoid.	1978	219040
[uremic osteodystrophy. critical evaluation of the radiologic and humoral indices of bone resorption].		2003	262283
hypothalamic-pituitary responses to intracranial self-stimulation in the rat.	the effects on pituitary and adrenal hormones of intracranial self-stimulation (iss) and forced stimulation in rewarding (ps) and non-rewarding (nss) sites were investigated in adult male rats. growth hormone (gh) was suppressed during periods of iss and ps and rose sharply to a peak within 15 min of cessation. the interval between gh secretory episodes was significantly shortened during all 3 types of stimulation when compared to the normal rhythmic discharge observed in freely behaving baselin ...	1978	308836
eosinophil chemotactic factor (ecf). iii. generation in human peripheral leukocytes.	eosinophil chemotactic factor (ecf) can be released from human peripheral leukocytes by an ige-anti-ige reaction, by the calcium ionophore a 23187 and during phagocytosis. supernatants and sonicates of unstimulated cells contain little or no ecf. on stimulation, however, ecf activity increases in the cells and even more so in the supernatants. this holds for purified neutrophils (pmns) as well as for basophil-containing mononuclear cell preparations. these findings contrast with those in lung ho ...	1978	344230
[evaluation of the hemodynamics and the absorptive-excretory functions of the liver using radiopharmaceutical preparations].		2004	362109
[laboratory experiments with a polyvalent extract vaccine for oral immunization against e. coli enteritis].	bacteria of e. coli causing enteritis can be extracted by edta-sodium. these extracts having lower dry weights result in better protective effects in contrast to sodium-deoxycholate extracts. the edta-sodium extracts can be concentrated, purified and sterile filtrated. thus the production of polyvalent vaccines is possible. a direct relation exists between the effectiveness of the extracts and the virulence of the strains used for extraction. the more virulent the original strain the better is t ...	1978	373349
suppressor of deoxythmidine monophosphate uptake in saccharomyces cerevisiae.	although yeast cannot normally incorporate exogenous deoxythymidine 5'-monophosphate (dtmp) into deoxyribonucleic acid, mutants able to do so have been isolated. we have characterized a recessive suppressor of dtmp uptake (sot1) that prevents strains carrying either tup1, tup2, or tup4 from growing on selective medium. the sot1 mutation maps between rad1 and the centromere of chromosome xvi, and is unlinked to any of the tup mutations. the sot1 mutation does not suppress the other pleiotropic ef ...	1979	374400
toward an effective system of ambulatory health care evaluation.		2004	412153
[autoradiographic studies on the distribution of 14c-piracetam in the simian brain].	autoradiography of the brain of the monkey callithrix jacchus 2 and 6 h after oral application of 200 mg 14c-piracetam/kg (2-oxo-pyrrolidine-l-acetamide-2-14c) shows that the drug is preferably concentrated in the cortex of cerebrum and cerebellum. this specific affinity of piracetam which was observed earlier in dog and rat is thus confirmed in the primate and seems to be species independent. beside the dominant cortical concentration there is a characteristic storage of piracetam in many nucle ...	1978	415743
the construction of a membrane slide support for the observation of living cells.	the construction of a slide for examining living cells under the microscope under controlled conditions is described.	2004	423235
[survey of late results of surgical treatment of atrial spetal defect (secundum type) (author's transl)].		2004	438563
[endocrinological diagnosis of pituitary neoplasms].		2004	438581
familial dupuytren's contracture with predominantly female expression.	a family pedigree is described in which a strong dupuytren's trait is manifest predominantly on the female side. the genetic aspects of the condition are reviewed and the importance of gene penetrance is stressed.	2004	444771
[ige determination (rist, prist and others)].		2004	490927
serum-cholesterol-binding reserve in patients with the nephrotic syndrome.	hyperlipidemia and premature atherosclerosis are known metabolic complications in patients with the nephrotic syndrome. in this study, we have measured serum levels of cholesterol, triglycerides and serum-cholesterol-binding reserve (scbr) in 22 patients (14 men, 8 women) with the nephrotic syndrome and in 21 hyperlipidemic men who served as control subjects. serum cholesterol levels were higher (p less than 0.005) in patients when compared to those of controls while triglyceride levels did not ...	2004	492425
[the effect of substance p on smooth musculature of the gastrointestinal tract (proceedings)].		1979	515151
[contributions of thoracic surgery in the research institute for pulmonary diseases and tuberculosis since its founding and under the presence conditions in the treatment of specific and nonspecific lung diseases (author's transl)].	thoracic surgery is done in the research institute for pulmonary diseases and tuberculosis for about 25 years. 2463 lung resections on account of tuberculosis, 934 lung resections on account of intrathoracic tumors, among them 795 suffering from bronchial carcinoma, 422 operations because of nonspecific pulmonary diseases (bronchiectasis, lung abscess a.s.o.) and nearly the same number of operations because of spontaneous pneumothorax were performed in this time. cystic lung disease, bullous emp ...	1979	516807
pathogenetic mechanisms in legionnaires' disease.		2004	519205
[normotensive pheochromocytoma].		2004	520932
fallacies of medially wedged heel for valgus foot.		2004	521647
arrest of alveolar multiplication in kyphoscoliosis.	a detailed morphometric study of the lungs of an adult patient with severe kyphoscoliosis of childhood onset is reported. the number of alveoli was less than the normal adult range and corresponded to the predicted values for a 12-month-old infant. this may have been a result of both premature cessation of alveolar multiplication as well as alveolar atrophy. the alveolar size was larger than normal suggesting that after cessation of alveolar multiplication further lung growth occurred by an exce ...	2004	523187
dna methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes.	the restriction enzymes hhai and hpaii, whose activity is inhibited by cytosine methylation within their recognition sites, have been utilised as probes to study methylation in the vicinity of the ovalbumin gene in dna from various chicken tissues. this was complemented by a preliminary study of methylation in the regions of chicken ovotransferrin (conalbumin), ovomucoid and beta-globin genes. from our data we conclude that hai or hpaii sites can be divided in 3 classes according to their patter ...	1979	523314
plasma hemoglobin in rectal or intravenous hydrogen peroxide for extrapulmonary oxygenation.		1979	524918
case reports: cryptococcosis.		2004	535192
[repair of huge hernia in scar].		2004	535813
alteration of tissue zinc distribution and biochemical analysis of serum following pinealectomy in the rat.	eight weeks following pinealectomy in adult male wistar rats, zinc levels of various tissues were found to be significantly altered: zinc in thoracic aorta was significantly increased, and in serum, pituitary, adrenal, heart, lung, and body hair, it was decreased. serum biochemical analysis indicated that there was a significant elevation of cholesterol, alkaline phosphatase, sodium, urea, and creatinine in serum from pinealectomised rats. liver, spleen, and thymus weights were lower following p ...	1979	544273
[lumbosacral radiculography with dimer-x and amipaque. advantages, side effects and possible late complications].		2005	551604
the aching mouth and the aching psyche.		2005	1074368
the selective suppression of an antibody response to a given antigen.		1976	1084334
alteration of colony-stimulating factor output, endotoxemia, and granulopoiesis in cyclic neutropenia.	cellular and humoral factors involved in the regulation of granulopoiesis were evaluated in two patients with cyclic neutropenia by utilizing the agar-gel marrow culture technique to serially study marrow granulocytic colony-forming capacity (cfc) and the urinary output of colony-stimulating factor (csf). csf output varied inversely with peripheral neutrophil counts and directly with monocyte counts and evidence for infection (endotoxemia and/or staphylococcal abscesses). following autologous in ...	1976	1087533
psoas abscess localization by gallium scan in aplastic anemia.	gallium 67 scanning is an effective method of detecting inflammatory lesions, especially abscesses. a 10-year-old boy with aplastic anemia and severe leukopenia and granulocytopenia had a psoas abscess diagnosed by gallium scan. the patient died with candida spesis 18 days after bone marrow transplantation. at autopsy, a chronic psoas abscess with candida was found. the gallium scan offers a clinically effective and noninvasive means of evaluating suspected infection in the granulocytopenic pati ...	2005	1091749
[in memory of jirŕ kruml, m.d., c.sc].		2005	1104202
baillière tindall prizewinner .1. the clinical nurse consultant.		2005	1129151
femoral percutaneous catheterization in infants and small children for cerebral angiography.	an improved technique of selective cerebral angiography for infants and small chicken is described. the needle is inserted approximately 45 degrees to the skin in order to avoid subintimal placement of the tip. after good backflow is established, the guidewire is advanced to a position in the descending aorta. a no. 3 polyethylene catheter and 21-gauge scalp vein needle were most successful.	1975	1153751
child care in the people's republic of china--1973. part ii.		2005	1168896
failure to consult specialist.		2005	1173090
effect of altitude relocations upon aado2 at rest and during exercise.	the supine pulmonary venous admixture (shunt) has been measured at cerro de pasco, 4,350 m altitude in eight subjects native to high altitude (han) under resting condition. alveolar-arterial o2 tension difference (aado2) was also determined at rest and during exercise. the same subjects were studied again after 10 days' sojourn at sea level in lima at 150 m altitude. they were compared with four subjects from sea level (sln) who were studied first at lima and after 2 and 10 days at cerro de pasc ...	2005	1176413
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 43-1975.		2005	1178005
task characteristics and a stage 6 sensorimotor problem.	a previously demonstrated high rate of failure on a stage 6 sensorimotor means-end problem, of children otherwise inferred to be in stage 6 development, prompted a study of task characteristics of the problem. a component part of the task was modified by introducing an additional visual cue; the purpose of the problem was unchanged. results indicated that problem solving was facilitated in the transformed condition, with older subjects performing somewhat better than younger subjects. the author ...	2005	1183275
[pre- and postoperative radiotherapy of laryngeal cancer].		2005	1196026
a volumetric assessment of pollen levels in the air of ann arbor, michigan.		2005	1196148
[repeated obtaining of dog peritoneal macrophages and their cultivation in vitro].		1975	1214674
human placental lactogen concentration during physiological fluctuations of serum glucose in normal pregnant and gestational diabetic women.	oral glucose tolerance tests (ogtt) were carried out in 9 normal pregnant women and 11 non-obese gestational diabetics in late pregnancy. all samples were analysed for the content of glucose, insulin and placental lactogen hormone (hpl). furthermore, spontaneous changes in the serum hpl concentration during a 3 h period were studied in 6 normal women in the 2nd half of pregnancy. during ogtt only small and insignificant changes in the level of hpl were observed in both the normal subjects and th ...	1975	1242271
attenuated, streptomycin-dependent salmonella typhi oral vaccine: potential deleterious effects of lyophilization.	four studies were done with streptomycin-dependent salmonella typhi as an oral, attenuated vaccine. studies 1 and 3 employed freshly harvested vaccine, whereas studies 2 and 4 involved lyophilized vaccine. five to eight doses (3 x 10(10)-10(11) organisms/dose) were given; oral streptomycin (1.0 g) was administered concomitantly in studies 2 and 3, with only two of the doses of vaccine in study 1, and was not given in study 4. no adverse reactions were encountered in 179 vaccinated men, and 94% o ...	1976	1262709
[scheele research and acclaim in travels to other countries. the 250th birthday of carl wilhelm scheele].		2005	1287672
[primary breast cancer: conservation therapy].	a series of 200 patients with primary breast cancer, treated with breast conservation between 1981 and 1988, was analyzed retrospectively. the mean age was 54 +/- 14 years and mean follow-up 36 months. 58 patients (29%) were in pathological stage i, 85 (42.5%) in ii a, 34 (17%) in ii b, and 7 (3.5%) in iii. 16 (8%) were in clinical stages i-ii; 40 (20%) had multifocal tumors and 40 intraductal components. 45% of the lesions were excised with good margins, 13.5% with close margins (0.5 cm), 9% wi ...	2005	1317331
thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. a study in parabiotic mice.	this study was designed to resolve the long standing controversy as to whether hematogenous precursors or resident intrathymic precursors maintain thymocytopoiesis in postnatal life. the kinetics of thymic chimerism was examined over a 21-wk period in 105 pairs of nonirradiated, thy-1-alloantigen-disparate, parabiotic b10.s mice. thymic chimerism reached reached maximum levels of 25% in the thy-1b and 16% in the thy-1a partners (mean 20.5% and 9.8%, respectively) 6 to 7 wk after parabiotic union ...	2006	1347301
expression of her2/neu oncogene product p185 in correlation to clinicopathological and prognostic factors of gastric carcinoma.	the expression of the her2/neu gene product p185 was retrospectively analyzed in 58 patients with gastric carcinoma. the results were correlated to various clinicopathological and prognostic factors. positive membrane staining for p185 could be detected in 38% of the patients (22/58). membrane staining was significantly greater in well and moderately differentiated tumors of the intestinal type when compared with poorly differentiated lesions and carcinomas of the diffuse type (p less than 0.01) ...	2006	1352299
non-beta-adrenergic-mediated peripheral circulatory hyperkinesia in hyperthyroidism.	systolic time intervals and brachial circulation, evaluated by pulsed doppler in terms of arterial diameter, blood velocity and flow, and vascular resistance, were studied in 12 hyperthyroid patients and in 12 normal controls. in patients, arterial circulation was studied before and during mechanical exclusion of the hand, and hemodynamic measurements were repeated after beta-blocker treatment and after obtainment of euthyroid state. compared with controls, patients had higher heart rate (p < 0. ...	2006	1361313
midwifery and body fluid contamination.		2006	1392970
[transient, prolonged, combined sicca syndrome of the eyes and mouth. occurrence along with a common cold in an 8-year-old girl].	a girl of eight years fell ill with signs of common cold and bronchitis. already on the second day of illness, before any treatment was started, she showed symptoms of a sicca-syndrome, beginning in the eyes, later the mouth. ophthalmologic examination showed keratitis filiformis, histology of the salivary glands in the mucosa of the mouth was normal. local substitution therapy led to subjective improvement. the disorder of secretion persisted for four months only, then rapid restitutio ad integ ...	2006	1435804
design and inhibitory properties of synthetic bowman-birk loops.	a cyclic tridecapeptide based on the sequence of an anti-tryptic loop of a bowman-birk inhibitor was synthesized, and demonstrated to be active as an inhibitor of trypsin. molecular modeling of this sequence suggested an improved sequence which demonstrated an order of magnitude improvement in the inhibitory constant.	2006	1446974
what role will residency education take in the profession by the year 2000?	residency education has enjoyed relatively slow but steady growth since its inception in the mid-1970s. a certain segment of recent graduates consider graduation from optometry school as entry level and perceive the need for additional clinical education. the creation of new residency programs and the expansion of existing ones may occur in a variety of settings. for residency education to realize its full potential, optometry must seek federal support for post-graduate clinical education. this ...	2006	1447463
the na+/glucose cotransporter (sglt1).	an important class of na+ transport proteins is the cotransporters. they exist in bacteria and animal cells and are responsible for the "active" accumulation of sugars, amino acids, carboxylic acids and some ions, e.g., i-, cl-, and po-4, in cells. in the small intestine and renal proximal tubule the cotransporters play an important role in the transport of salt and water across the epithelia. the most well known and best characterized na+ cotransporter is the intestinal brush border na+/glucose ...	1992	1449065
what's your assessment? scabies.		2006	1482627
polyol pathway-mediated changes in cardiac muscle contractile properties: studies in streptozotocin-diabetic and galactose-fed rats.	contractile properties of left ventricular papillary muscles and atria from streptozotocin-diabetic and from non-diabetic rats fed a 40% galactose diet were measured in vitro. there was a characteristic slowing of twitch responses for both tissues and both treatments (p < 0.05). time to peak contraction was prolonged by 18-33% and maximum rate of contraction was reduced by 10-17%. relaxation was also affected, with a 13-37% increase in half-relaxation time and a 7-25% reduction in the maximum ra ...	1992	1489541
ga-67 citrate scan in vascular graft infection.	the clinical utility of the ga-67 scan has been studied in 9 patients with clinical suspicion of vascular graft infection. eleven grafts were analyzed: 4 aortobifemoral, 2 iliofemoral, 3 femoropopliteal, 1 axillofemoral, and 1 axillobifemoral. the ga-67 scan was positive in 8 grafts with bacteriological proof of infection and negative in 3 grafts in which infection was ruled out by clinical follow-up. a ga-67 scan also demonstrated the spread of infection to the thigh in two patients and to the ...	2006	1489633
activation of solubilized g-proteins by muscarinic acetylcholine receptors.	binding of gtp and its analogue, guanosine 5'-o-[gamma-thio]triphosphate (gtp[s]) to g-proteins, and release of gtp[s] from g-proteins are stimulated by muscarinic acetylcholine (mach) receptors in intact cardiac membranes. upon solubilization of receptors and g-proteins by membrane extraction with the detergent, 3-[(cholamidopropyl)dimethylammonio]-1-propanesulphonate, followed by sucrose density gradient centrifugation, agonist-liganded mach receptors stimulated binding of gtp[s] and hydrolysi ...	1992	1489667
carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i.	the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ...	2006	1525184
acupuncture analgesia.	acupuncture-produced surgical analgesia has been demonstrated in a wide variety of species under experimental and clinical circumstances. the main advantage is that no depressant drugs need to be used. the disadvantages of its use are unfamiliarity, the need for special equipment, inconsistent effects, and lack of restraint.	1992	1533972
diagnosis of sickle cell disease in chronically transfused patients.	standard electrophoretic methods for the diagnosis of hemoglobinopathies are confounded in individuals chronically transfused. we present the accurate diagnosis of sickle cell disease in two such transfused patients by the application of polymerase chain reaction technology to analyze patient's hemoglobin beta-chain genes directly.	1992	1550267
the carpal tunnel syndrome: part ii.	the carpal tunnel syndrome is a compression of the median nerve within the carpal tunnel with very specific signs and symptoms. anatomical dissection of 156 wrists is presented and then the authors compare their findings with the findings of other investigators. the purpose of this article is not to present results but rather to discuss the anatomic entities involved with the syndrome and to present the open treatment modality.	2006	1550309
[local meeting series--a model for continuing education of the general practice staff].	during the period january 1987 to june 1990 28 educational afternoon meetings were held for the office staff and nurses in general practice in bodø, as well as for the nurses in the bodø emergency clinic/service. office staff and nurses in the occupational health service were also invited, bringing the number up to 42. on average 40.0% of the invited persons attended the meetings. each meeting lasted 2 hours. the number attending the last meetings was so few that the series was discontinued. how ...	2006	1557764
schizophrenia: gender and familial risk.	the morbid risks for schizophrenia and any nonaffective psychosis in the first degree relatives of male and female schizophrenic probands were compared utilizing cox proportional hazards models. the schizophrenic probands (275 male; 106 female) were drawn from a larger sample of hospitalized patients obtained by systematically screening all psychiatric admissions to 15 facilities over a six-year period. proband diagnoses (dsm-iii) were based on a direct assessment of the patient and a review of ...	2006	1560406
a double-blind trial of nocturnal supplemental oxygen for sleep desaturation in patients with chronic obstructive pulmonary disease and a daytime pao2 above 60 mm hg.	the efficacy of nasal oxygen during sleep was evaluated in patients with copd, episodic rapid eye movement sleep desaturation, and a daytime pao2 greater than 60 mm hg. the double-blind, randomized 3-yr trial used nasal oxygen versus room air in two groups of nocturnal sleep desaturating subjects. the setting was the outpatient chest clinic of a veterans affairs medical center. there were 51 patients with moderate to severe copd, daytime pao2 greater than or equal to 60 mm hg: 38 with proven rem ...	2006	1586049
[a more hemodynamic surgery...].		2006	1594838
uterine leiomyomas: cytogenetic and histologic profile.	the main purpose of this study was to determine whether there is any correlation between the cytogenetic abnormalities and histology in uterine leiomyomas.	2006	1635734
effects of norethisterone on pressor response to angiotensin ii in men.	we examined the effects of norethisterone and/or mestranol on the pressor response to angiotensin ii in 20 healthy men.	2006	1635747
[radiation protection in diagnostic radiology].	for every diagnostical x-ray radiation exposure the applied dose has to be limited to the smallest possible value. within the scope of a general swiss survey it has been found that in the various medical practices and hospitals the applied doses varied quite strongly. the main reasons leading to an overdose were the operating conditions of the x-ray and film processing equipment, the film and foil materials and improper filming techniques. the applied single dose served as a measure for the radi ...	2006	1636159
inhibition of nitric oxide synthase blocks n-methyl-d-aspartate-, quisqualate-, kainate-, harmaline-, and pentylenetetrazole-dependent increases in cerebellar cyclic gmp in vivo.	the synthesis of nitric oxide by brain slices has been demonstrated in several laboratories. in addition, in vitro studies have demonstrated stimulation of nitric oxide synthesis by excitatory amino acid receptor agonists. these data have led to the hypothesis that this readily diffusible "intercellular messenger molecule" acts to generate a cascade effect by activating guanylate cyclase in several cell types and thereby augment levels of the second messenger cyclic gmp (cgmp). therefore, we eva ...	1990	1693947
peptide regulation of adrenal medullary function.	the discovery of peptides in the splanchnic nerve and adrenal gland, and their co-existence with conventional neurotransmitters raises questions about their possible functional roles in catecholamine (ca) secretion and gene transcription in the adrenal gland. short-term, stress-induced ca secretion is regulated biphasically by substance p (sp) which inhibits acetylcholine (ach) action at sp greater than 10(-6) m and facilitates ca secretion in response to metabolic and physical stressors, ach or ...	1990	1694230
[clinico-morphological signs of different forms of destructive pancreatitis].	clinicomorphological comparisons in 434 cases of destructive pancreatitis showed that macroscopic signs of destruction develop in the first 12 hours from the onset of the attack. the elaborated criteria make it possible to evaluate the main morphological components of destructive pancreatitis--pancreonecrosis proper, parapancreatitis, peritonitis, and "polyvisceritis" and to use therapeutic measures on an individual basis.	2006	1779556
[conservative celioscopic treatment of isthmic ectopic pregnancies].	twenty-six ectopic pregnancies located strictly within the isthmus were treated surgically using conservative laparoscopic techniques. in each and every case the triton's monopolar electrode was used to perform salpingostomy which was followed by the aspiration of the trophoblast. this therapeutic approach is very reliable since only one failure was observed (3.9%), requiring a further operation during which salpingectomy was carried out by laparoscopy. it was possible to evaluate subsequent fer ...	2006	1838757
olfactory dysfunction in parkinson's disease.	an olfactory function test in 18 patients with parkinson's disease (pd) and 10 age-matched control subjects was performed. both detection and recognition thresholds were measured with five kinds of synthesized odorants (t & t olfactometry). before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia. both detection and recognition thresholds in patients with pd were significantly elevated in comparison with those of control subjects. auditory ...	2007	1852411
[analysis of mortality time series in malignant lung tumors and its future trends].	time series of standardized mortality from malignant neoplasms of the trachea, bronchi and lungs in 1965 to 1986 were examined by a group of programmes for computer supported prognoses. czechoslovak data were compared with those from austria, sweden and england and wales. extrapolation of time series revealed conclusively that the development in czechoslovak men is alarming. while in all compared countries there was in recent years a declining mortality, in czechoslovakia the mortality is rising ...	2007	1853143
[conservative therapy of ulcerative colitis and crohn disease].	basis treatment of severe ulcerative colitis and crohn's disease comprises the systemic administration of corticosteroids. if the conditions are less severe, treatment with oral sulfasalazine or 5-aminosalicylic acid (5-asa) can be attempted. distal ulcerative colitis may respond to topical corticosteroids of enemas with sulfasalazine or 5-asa. in long-term treatment with high-dose corticosteroids, azathioprine and 6-mercaptopurine may be employed to reduce the corticosteroid requirement. there ...	2006	1855750
characterization of activation and deactivation pathways of 4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (nnk) in rat hepatocytes.	we have characterized the metabolism of 4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (nnk) in cultured rat hepatocytes and have established the relationship between various metabolic pathways and single-strand breaks (ssb) in dna. metabolism of [5-3h]-nnk by carbonyl reduction, alpha-carbon hydroxylation and pyridine n-oxidation was linear from 0.5 to 6 h with 0.25-2 x 10(6) hepatocytes. using an alkaline elution assay, we observed that nnk induces ssb in dna in a dose- and time-dependent m ...	1991	1855907
predominant expression of lambda light chain in adult cases with non-t-cell acute lymphocytic and chronic myelogenous leukemia in lymphoid blast crisis.	the authors investigated cytoplasmic immunoglobulins of the leukemic cells from 20 adult cases with non-t-cell acute lymphocytic leukemia (all) and from three cases with chronic myelogenous leukemia in lymphoid blast crisis using immunoelectron microscopy. they also studied these cases using various monoclonal antibodies. of the 23 examined cases, nine were negative for both heavy and light chains of immunoglobulins; the authors defined these as common all. two cases were positive for the mu cha ...	2007	1906773
corticotropin-releasing hormone is a rapid and potent convulsant in the infant rat.	corticotropin-releasing hormone (crh) administered into the cerebral ventricles of rats during the first postnatal week caused a specific and stereotyped behavior sequence: rhythmic chewing and licking (jaw myoclonus) were followed by 'limbic'-type seizures. the onset of the seizures was much more rapid (2-45 min vs 3-7 h) than in adult rats, and the convulsant doses were much lower (50 x 10(-12) mol per gram brain weight vs 750 x 10(-12) mol per gram brain weight in adults). crh potency in indu ...	1991	1914160
nasopharyngeal carcinoma with spinal secondaries.	nasopharyngeal carcinoma has been reported to have a higher incidence of distant metastases as compared to other head and neck cancers. distant metastases of nasopharyngeal carcinoma has been reported in the bones, lungs, liver, distant lymph nodes, brain and porta hepatis. this report presents a case of nasopharyngeal carcinoma with secondaries in the extradural space at the thoracic level of the spinal cord which hitherto has been an unreported site.	2007	1919352
observation and theory in psychoanalysis: the self psychology of heinz kohut.	the development of self psychology by heinz kohut illustrates the influence of observational method on theory formation in psychoanalysis. in 1959 kohut began to emphasize empathy and introspection over the traditional combination of free association and evenly suspended attention. this became an important part of a process of revision in psychoanalytic theory which culminated in self psychology. this paper demonstrates how and why that particular change in observational method influenced that p ...	2007	1924603
central nervous system involvement during infection by phlebovirus toscana of residents in natural foci in central italy (1977-1988).	central nervous system (cns) involvement was detected during infection caused by the sand fly-transmitted phlebovirus toscana. one hundred fifty-five cases of toscana virus-associated meningitis or meningoencephalitis were identified in a survey that lasted ten years, conducted in two regions of central italy. diagnosis was performed by different serologic tests. a combination of hemagglutination-inhibition and plaque-reduction neutralization or indirect immunofluorescence for igm, and enzyme-li ...	1991	1951851
p-glycoprotein and progesterone receptor in human breast cancer.		1990	1974809
trade-off between gestational age and miscarriage risk of prenatal testing: does it vary according to genetic risk?	it has been generally assumed that as genetic risk rises, so the higher procedure-related miscarriage rates of diagnostic tests done earlier in gestation become more acceptable. to test the hypothesis a decision tree was used, in which the only differences between two tests a and b were that a was carried out earlier in pregnancy and was more likely to cause miscarriage. over a wide range of rankings for the three outcomes (procedure-related miscarriage of a normal baby, early termination of pre ...	2005	1978126
simultaneous assessment of inflammation and epidermal proliferation in psoriatic plaques during long-term treatment with the vitamin d3 analogue mc903: modulations and interrelations.	the influence of topical application of mc903, an analogue of 1 alpha,25-dihydroxyvitamin d3, on psoriatic plaques was investigated during a long-term treatment study. the parameters for epidermal growth and for inflammation were assessed on frozen sections using immunohistochemical methods to elucidate their modulations in time and the interrelations between the different cell types involved during treatment with mc903. biopsies were taken before and after 1, 2, 4 and 12 weeks of treatment. mon ...	2007	2018728
epidermal cytokines and their roles in cutaneous wound healing.	cytokines are small proteins or glycoproteins which are synthesized and secreted by a variety of cell types. through binding to specific receptors on target cells, these hormone-like products regulate many normal cell activities, including growth and differentiation, migration and immune functions. within the epidermis, keratinocytes are the major source of cytokines along with melanocytes and langerhans cells. in response to a variety of injurious stimuli, including ultraviolet irradiation and ...	1991	2064935
[treatment of occlusive diseases of blood vessels of the lower extremities at a specialized unit of the polyclinic].	organization of specialized angiological rooms with the day hospital in the polyclinic makes treatment of patients with obliterating diseases of peripheral vessels more effective. complex approach to treatment, the dynamic observation of the patients shorten the time of the coming of remission.	2007	2175518
lack of pqq dependent glucose dehydrogenase apoenzyme in some acinetobacter spp.	seventy four asaccharolytic strains of acinotobacter were tested for the presence of pqq dependent glucose dehydrogenase apoenzyme. this apoenzyme could not be detected in any of five strains of acinetobacter haemolyticus; it was also lacking in one strain of each a. junii and a. lwoffi.	1990	2176072
hypoglycemia risk during exercise after intramuscular injection of insulin in thigh in iddm.	the influence of bicycle exercise (60% of w170 [working capacity at a pulse rate of 170 beats/min]; 40 min) on the absorption of 125i-labeled fast-acting insulin (10 u; actrapid human insulin) after intramuscular compared with subcutaneous injection in the thigh was studied on 2 consecutive days in 10 insulin-dependent diabetes mellitus (iddm) patients. insulin absorption was measured as disappearance of radioactivity (1st-order elimination rate constants) by continuous external monitoring and a ...	1990	2190773
structural specificity for biological activity of trichostatin a, a specific inhibitor of mammalian cell cycle with potent differentiation-inducing activity in friend leukemia cells.	biological activities of four chemically synthesized trichostatin-related compounds, (r)-trichostatin a, (s)-trichostatin a, (r)-trichostatic acid, and (s)-trichostatic acid, were investigated. assays of differentiation-inducing activity in friend leukemia cells and g2-arresting activity in the cell cycle of normal rat fibroblast cells were used as monitoring systems for comparing the bioactivities of these compounds. the results clearly showed that both of the enantiomers of trichostatic acid h ...	1990	2211374
the first 2 years of the gambian national cancer registry.	we describe the creation, and the first 2 years experience, of the gambian national cancer registry. the major problems involved in the creation of such a registry in a developing country are discussed. the data accumulated show a low overall rate of cancer incidence compared to more developed parts of the world and indicate that the prevalent cancers, hepatoma, carcinoma of the cervix and lymphoma, are likely to be due to infectious agents. it is hoped that immunisation of children under one ye ...	2007	2223583
the first 2 years of the gambian national cancer registry.	we describe the creation, and the first 2 years experience, of the gambian national cancer registry. the major problems involved in the creation of such a registry in a developing country are discussed. the data accumulated show a low overall rate of cancer incidence compared to more developed parts of the world and indicate that the prevalent cancers, hepatoma, carcinoma of the cervix and lymphoma, are likely to be due to infectious agents. it is hoped that immunisation of children under one ye ...	2007	2223583