Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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immunization against q-fever of naturally infected dairy cows. | dairy cows infected naturally with coxiella burnetii as evidenced either by presence of phase ii agglutinating antibodies in the blood or by shedding c. burnetii in the milk, were vaccinated subcutaneously with formalin-killed phase i c. burnetii organisms. attempts to demonstrate c. burnetii in the milk of vaccinated dairy cows 47 days after vaccination were negative, while continuous shedding of c. burnetii in the milk of control non-vaccinated dairy cows was repeatedly demonstrated in the cou ... | 1975 | 1994 |
selection of chlortetracycline-resistant strain of coxiella burnetii. | 1975 | 1997 | |
precipitation of phase i antigen of coxiella burnetii by sodium sulfite. | 1975 | 2000 | |
characterization of an endotoxic lipopolysaccharide from coxiella burnetii. | phase i coxiella burnetii antigen isolated by phenol extraction from purified suspensions of c. burnetii in phase i is a complex lipopolysaccharide (lps) molecule containing substances typical of the bacterial lps. some endotoxic properties of this c. burnetii lps, namely pyrogenicity and skin epinephrine reaction in rabbits, hypothermia in white rats, lethal effect on chicken embryos or on actinomycin-d-treated mice are similar to those of lps isolated from other gram-negative bacteria. | 1976 | 5871 |
vaccination of naturally infected ewes against q-fever. | 1977 | 15446 | |
analysis of antibody response and immunoglobulins in sera of rabbits and guinea pigs immunized with coxiella burnetii. | rabbit and guinea pig sera and their immunoglobulin fractions (igm and igg) were examined by complement-fixation (cf), microagglutination (ma), opsonization-phagocytosis (op) and serum protection (sp) tests at intervals after immunization with live phase i and phase ii coxiella burnetii suspensions. in general, ma antibodies, but also decreased, earlier than cf antibodies. the anamnestic immune response was higher with lower primary doses. both phase ii and phase i cf and ma antibodies as well a ... | 1977 | 18924 |
the environmental fate of three carcinogens: benzo-(alpha)-pyrene, benzidine, and vinyl chloride evaluated in laboratory model ecosystems. | radiolabeled benzo-((alpha)-pyrene, benzidine, and vinyl chloride were evaluated in laboratory model ecosystems for environmental fate, degradation pathways, bioconcentration, and food chain accumulation. the comparative effects of microsomal detoxications were evaluated using the inhibitor piperonyl butoxide. the accumulation and bioconcentration of benzo-(alpha)-pyrene and benzidine were closely correlated with their octanol/water partition coefficients and water solubility. benzo-(alpha)-pyre ... | 1997 | 20063 |
[psychic help for aged people of day-care-centers by attending person-centered encounter groups (author's transl)]. | 45 old people (average age 72 years) took part in 9 person-centered encounter groups together with younger people (average age 32 years). psychological changes of the old people were collected by questionaires and compared to a control group of 38 old people who subsequently took part in 4 encounter groups without younger people. excerpts from the encounter talks were rated in certain variables. | 1997 | 20791 |
search for correlates of resistance to virulent challenge in mice immunized with coxiella burnetii. | mice immunized with live phase i or phase ii coxiella burnetii, with killed phase i or phase ii organisms or with trichloroacetic acid (tcae) or phenol (pe) extracts were resistant to intraperitoneal infection with phase i c. burnetii irrespective of whether or not they displayed phase i antibody response at the time of virulent challenge. increased phagocytosis of purified phase i organisms by blood leukocytes or peritoneal exudate cells (pec) was noticed only in mice with phase i agglutinating ... | 1977 | 22238 |
world medical assembly, dublin, 1977. | 1997 | 23488 | |
glutathione synthesis and degradation in fetal and adult rat liver and novikoff hepatoma. | 1978 | 28177 | |
seroepidemiological investigations in domestic ruminants from egypt, somalia and jordan for the demonstration of complement fixing antibodies against rickettsia and chlamydia (author's transl). | 1450 random serum samples of domestic ruminants from egypt, somalia and jordan were investigated for complement fixing antibodies against rickettsia and chlamydia. between 1.5 and 3.4% of the samples from the animals investigated had antibodies against the rmsf-group of rickettsia, with exception of the sera from somalian cattle and sheep from jordan. antibodies against rickettsia of the typhus-group were found in 4 cattle and 1 goat from jordan and 2 sheep from egypt; by agglutination test with ... | 1978 | 28651 |
influence of mild acid hydrolysis on the antigenic properties of phase i coxiella burnetii. | mild acid hydrolysis of phase i coxiella burnetii cells gradually cleaved off polysaccharide chains, which contain determinants of antigen 1, thus unmasking determinants of the diagnostically important antigen 2. this artificial phase i to phase ii conversion was reflected by changed serological activity in the complement-fixation (cf) test and by changed nonspecific phagocytosis. the product of mild acid hydrolysis can serve as a complex diagnostic preparation, because it reacts in the cf test ... | 1978 | 29469 |
immunological properties of the lipopolysaccharide-protein complex of coxiella burnetii. | purified lipopolysaccharide-protein complex (lps-pc) extracted by trichloroacetic acid from phase i coxiella burnetii organisms induced in mice and rabbits fair levels of antibodies directed to antigen 1 and antigen 2, as detected by complement-fixation (cf), microagglutination (ma), opsonization-phagocytosis (op) and serum protection (sp) tests. in guinea pigs only very low levels of ma antibodies against antigen 2 were demonstrated. in rabbit serum, ma antibodies directed to antigen 2 were fou ... | 1978 | 29470 |
experimental infection of hare (lepus europaeus) with coxiella burnetii and rickettsia slovaca. | hares (lepus europaeus l.) infected subcutaneously (s.c.) or per os with coxiella burnetii and s.c. with rickettsia slovaca overcame an inapparent infection accompanied by irregular rickettsaemia and distribution of rickettsiae to different organs and variable antibody response. neither riskettsia could be detected in faeces of infected animals, but c. burnetii was found in the urine of one hare, which died on day 13 post infection (p.i.). antibodies against c. burnetii persisted for one year of ... | 1978 | 30267 |
attempts at demonstration of lipopolysaccharide in phase ii coxiella burnetii. | comparison of some properties of phase i and phase ii coxiella burnetii cells suggests the presence of lipopolysaccharide (lps) also in the surface structures of phase ii cells. polysaccharide chains were released from them by mild acid hydrolysis and corpuscular residues resulting from such hydrolysis elicited in rabbits anti-lipid a-antibodies. toxicity for adrenalectomized and actinomycin d-sensitized mice was demonstrated with phase i cells, but not with much higher concentrations of phase i ... | 1978 | 35951 |
antibody response in man following a small intradermal inoculation with coxiella burnetii phase i vaccine. | a small inoculum (0.2 microgram) of phase i coxiella burnetii vaccine given to individuals previously sensitized to co burnetii elicited a positive skin reaction and a strong igm phase i antibody response as determined by microagglutination, complement fixation and microimmunofluorescence tests. a similar inoculum administered to nonsensitized individuals did not elitic a skin reaction nor stimulate a recognizable antibody response. serum from one of these sensitized and skin tested individuals ... | 1979 | 35962 |
[gastrointestinal hormones: new aspects and perspectives]. | 2001 | 37420 | |
inhibition by coxiella burnetii of ascites tumour formation in mice. | mice injected intraperitoneally (i.p.) with killed purified coxiella burnetii organisms were protected from ascites development and death caused by i.p. inoculation of sarcoma-180 cells. the extent of protection was a function of the relative dose of c. burnetii and tumour cells, and of the time of injection of c. burnetii. phase ii c. burnetii organisms exerted an antitumour protection at least as high as phase i c. burnetii organisms. | 1979 | 41443 |
suitability of coxiella burnetii strains for preparation of phase ii artificial diagnostic antigen for microagglutination test. | sensitivity in the microagglutination (ma) test of artificial (prepared by potassium periodate treatment) phase ii coxiella burnetii antigens depended on the c. burnetii strain used and the number of its chick embryo yolk sac passages. | 1979 | 42306 |
electron microscopy studies of the limiting layers of the rickettsia coxiella burneti. | surface layers of coxiella burneti studied at a high resoulution reveal a plasma membrane and an outer surface membrane 6 to 7 nm thick, and a thin, moderately electron-dense intermediate layer associated with the inner surface of the outer membrane of many cells. this layer appears to be unaffected by lysozyme treatment. ruthenium red staining was used to delineate a layer of filamentous material external to the outer membrane; this fuzzy layer has a mean thickness of 20 nm and is not often see ... | 1975 | 47324 |
[immunologic comparison between some wolbachiae and research of antigentic community with other members of the order of rickettsiales]. | the antigenic relationship between some rickettsiae of arthropods, which do not transmit germs pathogenic to vertebrates was investigated by agglutination and immunofluorescence techniques. the comparison of r. melolonthae, r. tipulae, r. cetonidarum, r. grylli and of the rickettsiae of the scorpion buthus occitanus shows that the wolbachiae are divided into three serological groups. the insect crystallogen rickettsiae belong to the first group, r. grylli and the scorpion rickettsia are antigeni ... | 1975 | 53109 |
a serial study of pregnancy proteins in primigravidae. | the plasma concentrations from four 'pregnancy proteins' and three steroid hormones have been measured throughout pregnancy in 15 primigravidae. two of the proteins, human placental lactogen (hpl) and pregnancy-specific beta1-glycoprotein (psbetag), are specific for pregnancy and correlate well with the stage of gestation. it is suggested that measurement of psbetag may be useful in assessing feto-placental wellbeing. neither of the pregnancy-associated proteins, steriod-binding beta-globulin (s ... | 1976 | 57799 |
editorial: chronic q fever or q fever endocarditis? | 1976 | 58210 | |
[the manuscript of joseph dind]. | 2001 | 60194 | |
q fever in iran. | 1976 | 61379 | |
preparing and staining of coxiella burnetii natural phase ii antigen for the microagglutination reaction. | an improved method of preparing coxiella burnetii natural phase ii antigen of high purity enabled its staining for use in the microagglutination reaction (mar). the antigen was as specific and sensitive for detection of phase ii antibodies as the artificial phase ii c. burnetii antigen prepared by periodate treatment from purified phase i cells of c. burnetii. | 1976 | 61717 |
a passive hemagglutination test for diagnosis of trench fever due to rochalimaea quintana. | a passive hemagglutination test devised for diagnosis of trench fever was easily performed and highly sensitive and specific. tanned sheep erythrocytes were sensitized with soluble antigen from rochalimaea quintana. the test detected antibody in six of seven cases of primary infection and in four cases of late, relapsed trench fever. titers of antibody ranged from 1:20 to 1:640. although both igm and igg antibody to r. quintana were detected by passive hemagglutination, igg appeared to be the ma ... | 1976 | 63526 |
fluoridised milk. | 2002 | 65544 | |
porphyria cutanea tarda associated with lymphoma. | three patients with porphyria cutanea tarda and lymphoma were seen at the mayo clinic. in one patient, the signs and symptoms of porphyria cutanea tarda and lymphoma occurred simultaneously, whereas in the other two, the porphyria was seen before the lymphoma occurred, three years before in one and one and a half years before in the other. involvement of liver or marrow was not related to the development of porphyria cutanea tarda in any of the 3 patients. the porphyria cutanea tarda was not eas ... | 1999 | 84468 |
serum alkaline phosphatase activity in acrodermatitis enteropathica: an index of the serum zinc level. | a significant positive correlation between serum zinc and serum alkaline phosphatase levels was demonstrated in four patients suffering from acrodermatitis enterophathica for which they received oral zinc sulphate therapy. in one of the male patients a significant inverse relation between serum zinc and serum copper was found. | 1999 | 84482 |
av program available on plastic bag system preparation of tpn solutions. | 1999 | 84531 | |
changes in muscle, liver, and plasma free fatty acid levels in the pigeon on acute exposure to cold. | adult pigeons were subjected to acute cold exposure (-25 degrees c; 30 min). fully-plumed birds, showed a pronounced increase in the level of ffa in the blood, but not in the liver or muscle. partially-defeathered (dorsum and pectoral regions) birds, likewise, showed a marked increase in plasma ffa level but failed to indicate any change in ffa levels in the liver or the muscle. it is concluded that even if the mobilized ffa may have supported calorigenic processes in the normothermic cold-expos ... | 1999 | 84555 |
[formamidase--microheterogeneity, catalytic properties and inhibitors (author's transl)]. | formamidase from rat liver proved to be microheterogenous. after preparative isoelectric focusing in density gradient columns, two peaks of formamidase with identical substrate specificity were identified. by analytical focusing in thin layers of polyacrylamide or sephadex g-75 sf, even five bands could be separated. their isoelectric points were 4.75, 4.78, 4.82, 4.92 (main band) and 5.11, but their michaelis constants did not differ significantly (54 to 62 mumol/l). an identical molecular weig ... | 1979 | 84781 |
expression in escherichia coli of chemically synthesized genes for human insulin. | synthetic genes for human insulin a and b chains were cloned separately in plasmid pbr322. the cloned synthetic genes were then fused to an escherichia coli beta-galactosidase gene to provide efficient transcription and translation and a stable precursor protein. the insulin peptides were cleaved from beta-galactosidase, detected by radioimmunoassay, and purified. complete purification of the a chain and partial purification of the b chain were achieved. these products were mixed, reduced, and r ... | 1979 | 85300 |
[relationship between the method of obtaining material and cytologic diagnosis of soft tissue tumors]. | 1999 | 85739 | |
albumin excretion in operating surgeons and in hypertension. | 2000 | 86009 | |
preganglionic neurons in the sacral spinal cord of the rat: an hrp study. | 1979 | 86176 | |
demonstration of rheumatoid factor idiotypic antigens on peripheral blood b and t lymphocytes from patients with rheumatoid arthritis. | antisera were raised against three polyclonal igm rheumatoid factors (rf). after adequate absorptions, the antisera were rendered idiotype-specific, as assayed by haemagglutination technique. by using the anti-idiotype antisera in indirect immunofluorescence on peripheral blood lymphocytes from the patients used as donors for the immunizing rf, it was demonstrated that 3-14% of the lymphocytes were stained, and thus had membrane-bound structures with idiotypic antigens similar to those of the ci ... | 2000 | 86203 |
[allergic complications in treatment with beta-lactam antibiotics]. | 2000 | 86323 | |
studies of human igm anti-igg cryoglobulins: ii. isoelectric focusing characteristics of the reactive antigen and residual serum igg pools. | the co-isoelectric focusing characteristics of the antigen-igg and residual igg pools in the serum of patients with mixed igm:igg cryoglobulinemia have been determined. the antigen igg purified from five igm cryoglobulins and the residual igg purified from serum depleted of cryoglobulin were radiolabelled and co-isoelectric focused in polyacrylamide gels in order to determine if the igm anti-globulin reacted in order to determine if the igm anti-globulin reacted with iggs having unique physicoch ... | 1979 | 86512 |
journal of autism and childhood schizophrenia. change of journal scope and title. | 2000 | 86533 | |
fluorescence polarization and pulse width analysis of chromosomes by a flow system. | isolated chinese hamster chromosomes have been analyzed using a multiparameter computer-controlled cell sorter to obtain information about unique properties of individual chromosomes. parameters other than dna content were sought that would further aid in distinguishing among chromosomes. the polarized emission of the dna-specific bis-benzimidazole dye hoechst 33342 was measured for each class of chromosomes identified by a distinct peak, i.e., differeing in dna content. the emission anisotropy ... | 2000 | 86570 |
factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine. | deaths from ischaemic heart-disease in 18 developed countries are not strongly associated with health-service factors such as doctor and nurse density. there is a negative association with gross national product per capita and a positive but inconsistent association with saturated and monounsaturated fat intake. the principal finding is a strong and specific negative association between ischaemic heart-disease deaths and alcohol consumption. this is shown to be wholly attributable to wine consum ... | 2000 | 86728 |
radiation doses after three mile island. | 2000 | 86763 | |
comparison of different antigenic preparations of coxiella burnetii used for antibody detection in guinea pigs. | the dynamics of antibody response in guinea pigs infected with coxiella burnetii was investigated by microagglutination (ma) and complement-fixation (cf) tests with different preparations of c. burnetii antigens. at the onset of antibody response the highest antibody titres were detected by the ma test with natural antigen 2, later on by the ma test with artificial antigen 2. throughtout the 1-year period of observation, the cf antibody levels were usually lower and, with the exception of the hi ... | 1978 | 87123 |
does it exist an internal impedence matching between macro- and micropulmonary vasculature? a simple model study. | 2000 | 87175 | |
communicating adverse drug reactions. | 2000 | 87560 | |
adult respiratory-distress syndrome in salicylate intoxication. | 2001 | 87755 | |
optimised blood-pressure. | 2001 | 87901 | |
performance of home blood-glucose meters. | 2001 | 87914 | |
[allergy and lectins: action between ige-mediated histamine release and glycoproteins from viscum album l. (mistletoe)]. | low-molecular constituents from viscum album (toxic) release, in irritatively toxic manner, histamine from human leukocytes without destroying the cells (cytotox test). this histamine release is prevented by preincubation with viscum lectins. the viscum lectin blocks the fc-portion of allergen-specific ige against anti-ige [125i]. lectin also inhibits the allergen-specific histamine release from human leukocytes occurring through ige; this can be demonstrated on leukocytes from patients with ato ... | 1978 | 88141 |
anaphylatoxin-induced shock and two patterns of anaphylactic shock: hemodynamics and mediators. | in the dog, different cardiorespiratory reactions were identified in two types of anaphylactic shock and in c5a-at (anaphylatoxin)-induced shock. all three types had in common a portal blood pooling with consequent decrease in the venous return, cardiac output, and arterial pressure. in anaphylaxis (a) of the first type, at a low titer of hemagglutinating antibodies, the latent period was 68 s and heart and lung function was unchanged. in the second type, at high titer, the latency was 19 s and ... | 1979 | 88165 |
audiotape slide teaching: use with automated and simple apparatus. | using a cross-over design trial and a series of 20 audiotape slide programmes on clinical physics and measurement, no difference in teaching effectiveness was found between their use with synchronised automated apparatus and simple manual equipment. in both cases 91% of the main lecture points were immediately recalled and there was a significant gain in knowledge from an average pre-test mcq score of 43%--76% post-test score. the advantages and disadvantages of automated and simple equipment we ... | 2001 | 88189 |
[alpha fetoprotein (its properties, function and significance in clinical practice)]. | 2001 | 88274 | |
hippocampal evoked potentials and eeg changes during classical conditioning in the rat. | hippocampal evoked potentials (eps) and eeg responses were studied in rats, using a classical conditioning paradigm (water, us), with a spatially discontiguous cs-us arrangement in order to separate the cs and goal-related responses. in early training, when the orienting score was high, the tone cs, instead of eliciting a definite ep, usually reset hippocampal theta activity in phase, i.e. theta rhythm became time-locked to cs. with further training, orienting activity (ori) decreased to the pre ... | 1979 | 88362 |
effect of radiotherapy on the neutrophil and the lymphocyte enzymatic equipment and serum immunoglobulins in patients with cancer of the larynx. | in 30 patients with cancer of the larynx, aged 40 to 70 years, treated by radiotherapy 6 to 9 years ago the decreased activity of neutrophil beta-glucuronidase and n-acetyl-beta-glucosaminidase accompanied by a decrease of absolute count of enzyme-positive cells was noted. numbers of acid phosphatase-positive neutrophils were also decreased. moderate increase of the neutrophil alkaline phosphatase activity and of numbers of enzyme-positive cells was another observed feature. the main finding in ... | 2001 | 88387 |
chronic cryptic q-fever infection of the heart. | evidence of chronic coxiella burneti infection of the heart, a disease previously considered peculiar to patients with valvular heart-disease, was found in a patient during routine serological tests before resection of a ventricular aneurysm and also by isolation of the rickettsia from the resected tissue. the patient had no symptoms or signs of q-fever endocarditis and none of the laboratory evidence usually associated with it. | 1979 | 88607 |
systemic hyalinosis (juvenile hyaline fibromatosis). ultrastructure of the hyaline with particular reference to the cross-banded structure. | systematic hyalinosis (juvenile hyaline fibromatosis) is characterized by hyalinized skin lesions. electron microscopic examination of a hyalinized skin tumor from a 19-year-old man with this syndrome revealed that the hyaline was composed of ruthenium red-positive ultrastructures (granules, filaments, and a kind of cross-banded structure), indicating the presence of glycosamino-glycan or glycoprotein, and a small number of thin collagen fibrils. using a new ruthenium red staining method combine ... | 1979 | 88923 |
search for epstein-barr and type c oncornaviruses in systemic lupus erythematosus. | lymphoblastoid cell lines were derived from patients with active systemic lupus erythematosus by allowing spontaneous transformation of peripheral b lymphocytes (b cells) harboring endogenous epstein-barr virus or by superinfecting peripheral lymphocytes with exogeneous epstein-barr virus. results of extensive studies aimed at identifying type c oncornaviruses in these lymphoblastoid cells were entirely negative by electron microscopy, dna-dna hybridization, reverse transcriptase assays, and coc ... | 1979 | 88943 |
[immunohistochemical study of the differentiation of the cephalic lobe of the adenohypophysis in chick embryos]. | it was shown by means of indirect immunofluorescence that acth appeared in the cephalic lobe of the chick embryo pituitary beginning from the 8th day of the development. a new tissue-specific antigen (a3) is revealed, which is localized in the cephalic lobe of adenohypophysis and becomes manifest at the 7th day of embryogenesis. quantitative analysis of acth and a3 localization in the cells of 11-day chick embryo adenohypophyses allows a conclusion that a3 is localized in corticotropic cells. | 2001 | 88969 |
the value of alpha-fetoprotein and beta-human chorionic gonadotrophin in the management of testicular tumours. | serum alpha-fetoprotein and beta-human chorionic gonadotrophin levels were estimated in 115 patients. sixty-nine patients had non-seminomatous germ cell tumours and 34 patients had seminomas. twenty-six patients showed elevated serum makers. | 1978 | 88986 |
a cerebello-pulvinar projection in the cat as visualized by the use of anterograde transport of horseradish peroxidase. | 1979 | 88999 | |
treatment of kidney-allograft rejection with cyclosporin a. | 1999 | 89479 | |
c.s.f. beta-endorphin in schizophrenia. | 1999 | 89490 | |
intraoperative nursing care for the orthopedic patient having regional anesthesia. | 2000 | 89648 | |
serum alphafetoprotein (afp) in bilharziasis. | two hundred and eighty-four patients of various ages from an endemic area, diagnosed as having bilharziasis by the presence of living schistosoma haematobium's ova in the mid-stream urine sample, have been investigated for the presence of alphafetoprotein (afp) in the serum. one hundred and forty-one (49.6%), were positive; no false positives have occurred. radioimmunoassay is capable of increasing the positivity rate still further. the detection of afp will be of limited value as a screening te ... | 2000 | 89881 |
child-resistant containers really are effective. | 2001 | 90232 | |
formaldehyde toxicity. | 2001 | 90277 | |
[basic behavior and behavior after stimulation of inflammatory cellular response, leukocytary chemotaxis and phagocytosis in aged subjects with depression of cellular immunity]. | a larger group of 70--75 years aged subjects was studied by means of various cutaneous tests, by e-rosette formation and by blastogenic response and 18 people showing a depressed cellular immunity were selected. these subjects and a similar control group with normal c.m.i. were further investigated in various condition of stimulation for cellular response in inflammation, chemotaxis, phagocytic activity and polysaccharide content in the granulocyte citoplasm. in general the former activity was n ... | 2001 | 90487 |
prolonged survival of corneal allografts in rabbits treated with cyclosporin a. | 1979 | 90771 | |
combined plasma exchange and immunosuppression in myasthenia gravis. | 2001 | 90826 | |
actual or standard bicarbonate. | 2001 | 90889 | |
prenatal diagnosis of congenital adrenal hyperplasia. | 1999 | 91004 | |
remission in acute myeloblastic leukaemia. | 1999 | 91055 | |
gastrin and spaghetti: what is physiological? | 2000 | 91933 | |
[histo- and cytological changes in mycosis fungoides from the point of view of cellular immunity]. | 2000 | 92109 | |
the development of the concept of lysosomes. a historical survey, with particular reference to the liver. | 2000 | 92465 | |
[relaxation of the diaphragm]. | 2001 | 92590 | |
antigenic determinants of horse cytochrome c for lymphocyte transformation: identification of an immunodominant peptide. | 1979 | 93078 | |
substance p infusion into substantia nigra of the rat: behavioural analysis and involvement of striatal dopamine. | the purpose of the present study was to characterize the nature of the behavioural response to substance p (sp) infusion into the substantia nigra and to evaluate this response in 6-hydroxydopamine (6-ohda) caudate lesioned rats. the effects of sp infusions (3 microgram in 1 microliter bilaterally) were assessed in an open field. two groups of rats were used: one with 6-ohda lesions in the caudate nucleus, and one with sham lesions. in sham rats, the first infusion produced a strong increase in ... | 1979 | 93550 |
"shikata" cell in liver biopsies. | 1999 | 93601 | |
hormone-responsive genes of the mouse mammary tumor virus. | by optimal hormonal treatment the production of exogenously transmitted mmtv can be stimulated in vitro to different degrees, depending on cultivation conditions and origin of tumor cells. moreover, after appropriate hormonal treatment, endogenous mmtv-y can be rescued from primary cell cultures derived from dimethyl benzanthracene- and hormone-induced c57bl/10 mouse mammary adenocarcinoma, as determined by reverse transcriptase assay, distribution of 3h-uridine-labelled viral particles, immunof ... | 1979 | 94006 |
investigation of the chemiluminescence associated with phagocytic and intracellular killing activity of human polymorphonuclear leucocytes and monocytes. | the chemiluminescence associated with phagocytic and intracellular killing activity of human polymorphonuclear leucocytes and monocytes was investigated. a significant, opsonization-dependent increase in photon emission of polymorphonuclear leucocytes and monocytes was observed induced by engulfment of opsonized, heat-killed and living fungi (saccharomyces cerevisiae), aggregated gamma globulin, latex and india ink particles. mononuclear cells displayed only minimal enhancement of photon emissio ... | 1978 | 94028 |
[determination of igm- and igg-antibodies to coxiella burnetii]. | 1979 | 94131 | |
antigenic analysis of acute hemorrhagic conjunctivitis viruses (enterovirus type 70). | the antigenic characteristics of enterovirus type 70 (ev 70) were investigated by means of cross and kinetic neutralization tests (nt). twelve strains of ev 70 isolated in a period from 1971 to 1976 were analyzed using seven rabbit and one monkey hyper-immune sera. all the strains investigated were found to possess a common and prime variant antigens in varying proportions. accordingly, ev 70 isolates were devided intratypically into three antigenic sub groups; (1) prototype-like (four strain fr ... | 1979 | 94146 |
local photochemotherapy in nodular prurigo. | fifteen patients with nodular prurigo were treated with a trioxsalen bath (50 mg/150 l of water) and uva given in an ordinary puva cabin. good results were observed in 8 and moderate in 7 patients in the initial phase. the result was good or excellent in 13 of the 15 patients during maintenance treatment. the good results are promising in the treatment of this chronic and otherwise therapy-resistant disease. | 1999 | 94220 |
thyroid hormone regulation of alpha-adrenergic receptors: studies in rat myocardium. | the effects of alterations in thyroid state on cardiac alpha-adrenergic receptors were investigated by the binding of [3h]dihydroergocryptine (dhe), a potent alpha-adrenergic antagonist. in seven experiments, cardiac membranes from euthyroid rats bound 47 +/- 9 fmoles dhe/mg protein (mean +/- se) at saturation and demonstrated a dissociation constant (kd) of 2.5 +/- 0.4 nm. hyperthyroidism, produced by parenteral injection of triiodothyronine, significantly reduced the binding of dhe at all conc ... | 1979 | 94388 |
genetic modulation of rna metabolism in drosophila. iv. measurement of rats of rna synthesis by density labeling. | accumulation of rna was measured in adult males of two genotypes: car bb/ybb- and car bb/ybbsuvar-5. the two genotypes have similar amounts of rdna, which is reduced in comparison to wild type (clark, strausbaugh and kiefer 1977). although genotypically bobbed, car bb/ybbsuvar-5 flies have a wild-type phenotype; car bb/ybb- flies are both phenotypically and genotypically bobbed (clark, strausbaugh and kiefer 1977). the wild-type phenotype observed in the car bb/ybbsuvar-5 flies is thought to be ... | 1979 | 94570 |
pressor effect of beta-adrenergic receptor blocking drugs in spontaneously hypertensive rats treated with clonidine. | the opposing effects on blood pressure of clonidine and beta-adrenoceptor antagonists which have been observed in some hypertensive patients were studied in conscious, spontaneously hypertensive rats. daily treament with clonidine (100 micrograms/kg, given by gavage) for 2 weeks significantly reduced systolic blood pressure and heart rate. after 2 weeks of treatment with clonidine, administration by gavage of d,l-propranolol (10 mg/kg daily) or sotalol (10 mg/kg daily) or intraperitoneal injecti ... | 1979 | 94621 |
[dural arteriovenous malformations in the region of the transverse-sigmoid sinus (author's transl)]. | 2000 | 94661 | |
[intracellular localization of alpha-fetoprotein and serum albumin in the central nervous system of the rat during fetal and postnatal development]. | the morphological localisation of alphafetoprotein (afp), serumalbumin (sa), transferrin and immunoglobulins (igg) has been studied in the developing central nervous system of the rat by immunocytochemical methods. evidence is presented of a highly selective staining for afp and sa, both proteins exhibiting the same topographical distribution. practically all the areas of the brain and the spinal cord are stained at a given moment of the developmental process. the labeling is cytoplasmic and in ... | 1979 | 95002 |
[dystrophy of bruch's lamina with or without para-foveal neovascularization]. | 2001 | 95395 | |
some characteristics of the insulin-induced potentiation to anaphylactoid reaction in sprague-dawley rats. | the insulin-induced sensitization to generalized and local anaphylactoid reaction evoked by dextran was studied in sprague-dawley cfy rats. the generalized reaction was shown to be potentiated by insulin given subcutaneously in a dose-related manner. the minimum effective dose was as low as 0.04 u/kg. when this dose was injected intravenously, a marked but short-lived potentiation was observed. the insulin response could be elicited throughout the whole year. the local oedema induced by subplant ... | 1979 | 95468 |
[immunological problems in oncology (author's transl)]. | the authors, after a view of the problems of immunology, regarding the most recent discoveries, deal with the conclusions about the immunological reactions in research and clinical oncology. many specific antibodies, formed as a result of the tumor, have been discovered in the field of research. it is impossible to say the same about human tumors and the probable hypothesis are numerous. the results until now obtained, even if they don't give a definite response, show that the immune defense of ... | 1979 | 95475 |
a study of rabbit plasma progressive antithrombinic activity during acute phase inflammatory reaction and in experimental nephrotic syndrome. | 1. the development of the progressive antithrombinic activity in rabbit plasma as a function of the level of the two alpha-macroglobulins in two experimental pathologies: acute phase inflammatory reaction and nephrotic syndrome, were studied. 2. in the first case, the antithrombinic activity is a result of the increased biosynthesis of plasmatic antithrombins: antithrombin iii, alpha 1 antitrypsin and alpha macroglobulins. 3. in the nephrotic syndrome, this activity follows the increase in the a ... | 1979 | 95682 |
modifications of the pattern-evoked potential (pep) in relation to the stimulated part of the visual field (clues for the most probable origin of each component). | a spatio-temporal analysis of the successive and simultaneous components of the pattern-evoked potential recorded on the scalp, and of their modifications according to which part of the visual field is stimulated, was carried out with 20 'normal' subjects, in order to shed some light on their most probable sites of origin. the stimulus consisted in the onset of a 20 degree checkerboard presented in runs of 75 stimuli each. its duration was 750 msec and its frequency of occurrence was random (abo ... | 1999 | 95712 |
minoxidil in resistant hypertension. | minoxidil in combination with propranolol and diuretics controlled the blood-pressure in a group of hypertensive patients who were resistant to treatment with large doses of standard drugs. the main problem was fluid retention but subjective side-effects were fewer than in a comparable group on other drugs. | 1999 | 95728 |
deficiency of the ninth component of complement in man. | the studies of serum from a case with c9 (the ninth component of complement) deficiency are described. a 29-year-old woman in good health was found to have low serum complement levels (ch50). c9 of her serum was undetectable by the hemolytic assay and by the immunochemical analysis but all other components were normal. it was demonstrated that low ch50 of her serum was due to the hemolysis of the sensitized sheep erythrocytes (ea) by the complement components from c1 to c8. | 1979 | 95812 |
[an experimental infection of hyalomma asiaticum and ornithodoros papillipes ticks with a single and combined infection with coxiella burnetii and dermacentroxenus sibericus]. | experimental infection of h. asiaticum and o. papillipes with coxiella burnetii and r. (d.) sibericus in different succession and individual study of these arthropods by means of the fluorescent antibodies method, ordinary microscopy and titration on laboratory animals have revealed an ambiguous outcome of the development of combined rickettsial infection in these ticks. the first agent obtained by the vector either prevents utterly the reproduction of the heterologous agent or inhibits its acti ... | 1979 | 95820 |