Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| d-alanyl-d-alanine carboxypeptidase in the bacterial form and l-form of proteus mirabilis. | membranes of the bacterial form and the stable and unstable l-forms of proteus mirabilis contain ld and dd-carboxypeptidase. the dd-carboxypeptidase is inhibited non-competitively by penicillin g. the enzyme of the bacterial form is highly penicillin-sensitive (ki - 4 x 10(-9) m penicillin g). inhibition is only partly reversible by treatment with penicillinase or by dialysis against buffer. in contrast, the dd-carboxypeptidase of the unstable l-form, grown in the presence of penicillin, is 175- ... | 1975 | 238 |
| proceedings: inducible tetracycline resistance in r+ and r- strains of proteus mirabilis. | 1975 | 2719 | |
| bactericidal activity and pharmacology of flucloxacillin. | flucloxacillin, a recent addition to the group of isoxazolyl penicillins, was studied in vitro and in normal volunteers. the bactericidal activity of the drug against most strains of gram-positive bacteria including penicillin-resistant staphylococcus aureus was similar to that of oxacillin and approximately fourfold greater than that of cloxacillin. each of the three penicillins was administered orally to a group of ten volunteers for eight days in a dose of 500 mg four times a day. the mean co ... | 1976 | 3969 |
| further observations on the potentiation of the antibacterial effect of methenamine by acetohydroxamic acid. | the use of methenamine in the treatment of urinary tract infections due to proteus species is limited by urine alkalinity. acetohydroxamic acid, an inhibitor of urease, maintains acidity despite growth of proteus in urine. easily achievable concentrations of acetohydroxamic acid in vitro systems that simulated the dynamics of the urinary tract potentiated the antibacterial effect of methenamine against proteus species. the combined use of a urease inhibitor and methenamine may be effective in th ... | 1976 | 4573 |
| studies of introital colonization in women with recurrent urinary infections. v. the inhibitory activity of normal vaginal fluid on proteus mirabilis and pseudomonas aeruginosa. | normal vaginal fluid from premenopausal volunteers was inoculated with 10 strains of proteus mirabilis and 14 strains of pseudomonas aeruginosa at ph's of 4.3, 4.6 and 4.9. all bacteria were killed at ph 4.3. nine of 10 strains of proteus mirabilis and 12 of 14 pseudomonas aeruginosa were killed at ph 4.6. only 4 of 14 strains of pseudomonas aeruginosa were killed at ph 4.9, while 8 of 10 strains of proteus mirabilis were killed at the same ph. we conclude that in comparison to the common 0 grou ... | 1976 | 4631 |
| comparative in vitro activity of cephalosporins. | the in vitro activity of cephalexin, cephaloridine, cephalothin, cephapirin, cefoxitin, cephamycin c, cepharadine and cefazolin was determined against 443 isolates of bacteria. at a concentration of 12.5 mug/ml, all of the cephalosporins inhibited more than 60% of the isolates of klebsiella pneumoniae. at the same concentration, cephalexin, cephaloridine, cephalothin, cephapirin, cephamycin c and cefazolin inhibited more than 90% of isolates of proteus mirabilis. all of the cephalosporins except ... | 1976 | 6411 |
| n-nitrosamine formation by cultures of several microorganisms. | of 38 pure cultures of microorganisms tested, only one, pseudomonas stutzeri, was capable of forming dimethylnitrosamine from dimethylamine and nitrite during growth. resting cells of p. stutzeri, cryptococcus terreus, escherichia coli, and xanthomonas campestris formed dimethylnitrosamine, although no nitrosamine was found in growing cultures of the latter three organisms. no nitrosamine was produced by either growing cultures or resting-cell suspensions of pseudomonas fragi or proteus mirabili ... | 1976 | 7197 |
| bactericidal mechanisms in rabbit alveolar macrophages: evidence against peroxidase and hydrogen peroxide bactericidal mechanisms. | the role of peroxidase-mediated bacterial killing by rabbit alveolar macrophages was examined. during 3 h of incubation in vitro, alveolar macrophages ingested and killed greater than 88% of the streptococcus faecalis, proteus mirabilis, or streptococcus pneumoniae present in the incubation mixture. preincubation of alveolar macrophages with inhibitors of catalase, 3-amino-1,2,4-triazole or sodium nitrite, did not alter their bactericidal potential. iodination of ingested zymosan particles, a pe ... | 1976 | 7533 |
| factors influencing the immune enhancement of intrapulmonary bactericidal mechanisms. | the effect of specific immunization on the antibacterial defense mechanisms of the murine lung was assessed against streptococcus pneumoniae, staphylococcus aureus, staphylococcus aureus (smith), serratia marcescens, klebsiella pneumoniae, proteus mirabilis, and pseudomonas aeruginosa. immunization by aerosol inhalation significantly enhanced the intrapulmonary killing of pseudomonas aeruginosa and proteus mirabilis but not the remaining organisms. with p. mirabilis, systemic immunization induce ... | 1976 | 9364 |
| effect of organic mercurials and sulfhydryl compounds on the urease activity of proteus: inhibition by urine and ascorbic acid. | meralluride, mercaptomerin, ethacrynic acid, and penicillamine inhibited urease activity of proteus mirabilis. the activity of the organic mercurials and ethacrynic acid was markedly inhibited by human and dog urine. antiurease activity could not be detected in the urine of a human and a dog given meralluride by injection. urine from patients receiving penicillamine also failed to inhibit urease activity. ascorbic acid inhibited, whereas dehydroascorbic acid enhanced, the activity of the mercuri ... | 1976 | 10828 |
| approach to a practical method for screening and identifying microorganism genera from urine (author's transl). | in this study the author reported upon a practical new system for screening and identifying the microbial agents causing urinary tract infections. this system is composed of a combination of 3 screening procedures (ph-value + nitrite-test + catalase-test) and 8 selective culture media for the purpose of genus identification within 24 hours (uripret-g). a total of 130 cultures was investigated. the employed microorganisms were mainly recovered from urine samples. they included the following speci ... | 1976 | 11179 |
| which gentamicin assay method is the most practicable? | 1977 | 14915 | |
| thermodynamic parameters of helix-random coil transitions in polypeptide chains. iv. random copolymers of l-alanine with l-glutamic acid. | ph-induced helix-random coil transitions in random copolymers of ala with glu have been investigated in order to determine the effect of ala on the stability of the helical state of polyglutamic acid. the free energies for the transfer of one uncharged glu residue from a random coil to a helix (deltago) have been determined from potentiometric titration curves by the method of zimm and rice. it has been shown that the introduction of ala hampers the transfer of a glu residue from a random coil t ... | 1999 | 15214 |
| intracellular nucleodepolymerase of bacteria, representatives of the proteus and providencia groups. its isolation and properties. | high activity of enzymes, splitting native, denaturated dna, deoxyribooligonucleotides and rna, was observed in cell free extracts of bacteria--representatives of 5 strains of proteus-providencia. some properties of nucleases were studied in cell free extracts. in the bacteria studied dnaases were thermolabile proteins, which were completely inactivated at 50-60 degrees, rnaases were more thermostable. the ph optima of the dnaases were at ph 9.0-11.0 in cell free system; rnaases were maximally a ... | 1976 | 17219 |
| cyclic guanosine-3',5'-monophosphate--mediator of the action of the hormaone erythropoietin. | 1977 | 18327 | |
| differential susceptibility of escherichia coli and proteus mirabilis to mouse urine and to urea. | the purpose of this investigation was to compare the antimicrobial properties of mouse urine and of urea against escherichia coli and proteus mirabilis. nornal urine was found to inhibit the growth of e. coli and p. mirabilis, whereas urine from diuresing animals permitted multiplication of these bacteria. addition of urea to urine from diuresing animals restored its bactericidal effect on p. mirabilis but not on e. coli. this bactericidal effect on p. mirabilis was dependent on the additive act ... | 1977 | 18546 |
| a new factor from enteric bacteria of rats amplifying induction of liver enzyme by glucocorticoid. 1. purification, properties and biological action. | 1. a factor, which amplifies the inductions of several liver enzymes by glucocorticoid, was partially purified from proteus mirabilis from rat intestine. the factor (amplifier) was completely inactivated by alpha-glucosidase, but not by other glycoside hydrolases, proteases, nucleases or phosphatases tested; it was also hydrolysed by hcl with liberation of reducing sugars. thus the oligosaccharide in this factor seems to be essential for the amplification. 2. in adrenalectomized rats the amplifi ... | 1977 | 21083 |
| a new factor from enteric bacteria of rats amplifying induction of liver enzyme by glucocorticoid. 2. mechanism of action. | 1. an amplifier of the action of glucocorticoid was purified from proteus mirabilis as described previously. it was found that it amplified the induction of liver tyrosine aminotransferase by dexamethasone markedly with doses of dexamethasone that caused minimal enzyme induction, but had little effect with doses that caused maximal induction. thus the amplification may represent a saving of glucocorticoid. the amplification of enzyme activity was brought about by increase in amount of enzyme. 2. ... | 1977 | 21084 |
| the effect of nutrient depletion on the drug resistance of a polymyxin-sensitive proteus mirabilis proceedings. | 1977 | 22714 | |
| effect of pharmacological substances on the development of hemorrhagic erosions and on the noradrenaline level in the stomach wall in rats. | hemorrhagic erosions of the gastric mucosa were produced through electric stimulation of immobilized rats via electrodes stuck into the muscles of the fore-paws. in the experiment there was applied square pulsed current of 5--7 v (per 10 rats) with frequency of 50 hz and the pulse time of 10 ms. prior to stimulation the rats received intraperitoneally one of the following drugs: clonidin (0.1 mg/kg), benactyzine (3 mg/kg), etherophen (20 mg/kg), benzohexonium (10 mg/kg), iprazid (100 mg/kg), amp ... | 1978 | 23958 |
| factors influencing the therapy of experimental proteus mirabilis meningitis in rabbits. | the therapy of proteus mirabilis meningitis with gentamicin alone and in combination with chloramphenicol was studied in a rabbit model. antibiotics were administered for 8 hr. samples of serum and cerebrospinal fluid (csf) obtained simultaneously were assayed at 2-hr intervals for antibiotic concentration and counts of bacteria in csf. the percentage of penetration (concentration in csf divided by concentration in serum x 100%) of gentamicin ranged from 14% to 23%, but very large dosages were r ... | 1978 | 24668 |
| significance of microbial contamination of stored cadaver kidneys. | the importance of microbial contamination of cadaver kidneys was assessed in 83 consecutively stored and transplanted kidneys. fourteen kidneys had a single positive culture during storage and five had multiple positive cultures. only one postoperative infection could be traced to kidney contamination during storage (candida wound infection). in three of 64 patients who received noncontaminated kidneys, posttransplant wound infections developed. no wound infections occurred in 35 patients who re ... | 1978 | 25059 |
| purification of dna polymerase from proteus mirabilis. | 1978 | 25512 | |
| the immunotropic effect of cysteine in the foetal period and in adult rats after administration of thymus-independent antigens. | 1977 | 25698 | |
| modification of the ph-auxostat culture method for the mass cultivation of bacteria. | 1978 | 26435 | |
| [effect of adsorption on the structure and properties of hemoglobin]. | adsorption spectra of hb+ and hbo2 adsorbed on silica and monolayers cholesterol supported on silica have been studied. it is shown that immobilization leads to new states of proteins, their properties depending on the nature of support and conditions of adsorption. adsorption of haemoglobin leads to its inactivation. the rate of inactivation decreases with an increase of surface concentration of haemoglobin and with simultaneous adsorption of inert proteins. | 2001 | 29668 |
| dipeptidylaminopeptidase and carboxypeptidase activities of the brush border of rabbit small intestine. | 1978 | 30675 | |
| the antimicrobial activity of urine of paraplegic patients receiving methenamine mandelate. | the antimicrobial activity of urine collected from adult male paraplegics ingesting methenamine mandelate (mm) was evaluated. the in vitro bacterial growth in urine from these patients was inhibited when the free formaldehyde (hcho) concentration was 10 to 22 microgram per ml. when the hcho concentration was in the region of 28 microgram per ml or greater, bactericidal effect became apparent. urine containing 1323 microgram of mm per ml with a ph of 5.9 when freshly voided had sufficient hcho to ... | 1978 | 30734 |
| protection against experimental proteus mirabilis pyelonephritis in rats and significance of immunity. | intraperitoneal immunization with formalin-killed bacteria as well as previous hematogenous infection with proteus o3h1 showed a protective effect against hematogenous pyelonephritis in rats when the homologous strain was used. transfer of hyperimmune antisera protected against hematogenously induced infection. neither intravesical or intraperitoneal immunization with formalin-killed bacteria nor transfer of urines containing antibodies of the igg class protected against ascending pyelonephritis ... | 1978 | 31056 |
| purification and structure of a new nucleotide from proteus mirabilis that amplifies induction of tyrosine aminotransferase by glucocorticoid. | 1979 | 34397 | |
| the role of thiamine in nervous tissue. | the possibility that thiamine (vitamin b1) has a role in nervous tissue that is independent of its well-documented coenzyme function is discussed. after reviewing the localization and metabolism of the vitamin and its phosphate esters, the effects of either thiamine deprivation or antimetabolites of thiamine on conduction and transmission, and the relationship between thiamine triphosphate and the genetic, neurological disease, subacute necrotizing encephalomyelopathy (leigh's disease), it is su ... | 1979 | 37452 |
| microbiological activity of cefazedone as compared to cefazolin and cephalothin. | in a comparison of the antibacterial activity of (6r,7r)-7-(2-[3,5-dichloro-4-oxo-1(4h)-pyridyl]-acetamido)-3-([5-methyl-1,3,4-thiadiazol-2-yl)-thio]methyl)-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid (cefazedone, refosporen) as compared to other cephalosporins it can be seen that cefazedone possesses good activity against gram-positive bacteria; as regards activity against enterobacteriaceae, in particular strains of e. coli, klebsiella species and proteus mirabilis, they fall w ... | 1979 | 39575 |
| ultraviolet irradiation disrupts somatic pili structure and function. | three piliated bacterial species were exposed to ultraviolet light (7 x 10(3) microw/cm2), and the effect of increasing duration of irradiation on the integrity of the somatic pili was quantitated by negative-stain electron microscopy. heavily piliated proteus mirabilis became devoid of pili after 20 min of irradiation, but escherichia coli and neisseria gonorrhoeae required 40 min for complete depiliation. partially purified proteus pili underwent progressive loss of structural integrity with i ... | 1979 | 40875 |
| [photodynamic effect of quinacrine on bacteria]. | the acridine dye quinacrine (qa) was tested with regard to the photodynamic action on bacteria (proteus mirabilis, escherichia coli). the absorption maximum of the yellow dye qa ist in contrary to the photodynamically active dyes methylene blue (mb) and thiopyronine (tp) situated in the short wave region of the visible spectrum. using for illumination a common light source--they have in general a weak emission in the short wave region--relatively high concentrations of qa are necessary for photo ... | 1979 | 42229 |
| [comparison of four recently introduced cephalosporins with respect to probability of resistance in multiresistant strains of escherichia coli, proteus mirabilis and klebsiella spec. (author's transl)]. | strains with the same number of resistances were arranged in so-called resistance classes. nine classes of resistance (0 to greater to or equal to 8) were formed by means of ten standard chemotherapeutics; the four new cephalosporins were excluded. for every resistance class frequency of cephalosporinresistance was described as coefficient ranging from 0 to 1 (fig. 1). in cephalothin the coefficients were markedly rising only in 6 (7)-fold resistant strains of the species examined. similar but s ... | 1979 | 44785 |
| [the distribution of minimal inhibitory concentrations of recently introduced cephalosporins in multiresistant strains of escherichia coli, proteus mirabilis and klebsiella spec. as revealed by zone sizes of a standardized agar diffusion test (author's transl)]. | strains of a species were divided into two groups according to the number of resistances (less than or equal to 4, greater than or equal to 5) using 10 standard chemotherapeutics regularly examined, the new cephalosporins not being among them. these groups of less than or equal to 4- and greater than or equal to 5-fold resistant strains were compared for each cephalosporin tested (fig. 1). the most different distributions of zone diameters (of both groups) were seen in cephalothin, whereas in ce ... | 1979 | 44786 |
| incompatibility of r plasmids from clinical material. | thirteen r plasmids derived from strains of e enterobacteriaceae isolated from clinical material have been characterized. they belonged to many incompatibility groups and differ widely respecting other phenotypic characteristics, even if they come from bacteria isolated from a small geographic area. | 1979 | 44944 |
| [in vitro activity of cefaclor (author's transl)]. | a comparative study was conducted on the in vitro activity of cefaclor and other oral cephalosporins against a large number of freshly isolated clinical strains of gram-negative and gram-positive bacteria. the activity of cefaclor against gram-positive pathogens is very similar to that of cephalexin. the action of cefaclor against streptococcus pneumoniae is superior. cefaclor is the most active antibiotic against strains of haemophilus influenzae, and is also more active than cephalexin and cep ... | 1979 | 45087 |
| esterase zymograms of proteus and providencia. | the intracellular esterases of 80 strains of proteus and providencia were analysed by the acrylamide-agarose zymogram technique using several synthetic substrates. the esterase bands were classified in five main groups. the alphaa-esterase bands hydrolysed alpha-naphthyl acetate and were resistant or relatively insensitive to di-isofluoropropyl phosphate (dfp). the alphab-esterase band hydrolysed both alpha-naphthyl acetate and alpha-naphthyl butyrate and were very sensitive to dfp. both groups ... | 1975 | 48538 |
| letter: antagonism of oxolinic acid by nitrofurantoin. | 1975 | 48654 | |
| infection caused by proteus mirabilis strains with transferrable gentamicin-resistance factors. | during a period of 10 weeks, four patients in one hospital became infected with gentamicin-resistant proteus mirabilis. in two of them septicaemia associated with indwelling catheters developed, one had urinary tract and wound infections, and in the fourth patient the organism was isolated from a superficial wound. the p. mirabilis strains showed multiple drug resistance. strains form the first three patients were apparently identical and were sensitive to tobramycin. their gentamicin resistance ... | 1975 | 48945 |
| micrococcal urinary-tract infections in young women. | in a prospective study in young women, novobiocin-resistant subgroup-3 micrococci were the second commonest cause, after escherichia coli; of acute urinary infections. proteus mirabilis was the only other causative organism. symptoms, pyuria, or possible aetiological factors were the same in micrococcal and coliform infections. the infecting micrococcus "biotype" was only rarely found among the normal flora of the genitourinary tract of young women, though other micrococci and staphylococci were ... | 1975 | 51404 |
| studies on lipopolysaccharides of proteus vulgaris serogroups. chemotypes of genus proteus lipopolysaccharides. | 1975 | 55287 | |
| [serological activity of different antigenic preparations of proteus in precipitation tests]. | 1975 | 55948 | |
| current questions on the tumour-associated antigens of chemically-induced tumours ii. in search of practical uses. | with special reference to tumours which were chemically-induced in animals, we present a brief review on the applicability of the results obtained, as to immunoprophylaxis and to immunotherapy. a search is made onto what are the mostly representative animal models for human studies. from the present available data, experimental chemically-induced bladder and colonic tumours seem to be the "best" models for human counterparts. | 1976 | 57809 |
| rational choice of penicillins and cephalosporins based on parallel in-vitro and in-vivo tests. | because of the unavailability of strictly comparable data, seven representative penicillins and the five cephalosporins currently used in britain were evaluated in parallel, both in vitro and in vivo. penicillin sensitive and resistant strains of staphylococcus aureus and proteus mirabilis were the main test organisms. minimum bacteriocidal concentrations of cloxacillin, flucloxacillin, cephalothin, and cephazolin in serum were much higher than conventional minimum inhibitory concentrations in t ... | 1976 | 61353 |
| a polyvalent human gamma-globulin immune to pseudomonas aeruginosa: passive protection of mice against lethal infection. | as a means to development of guidelines for therapeutic application to human disease, preparations of human polyvalent gamma-globulin immune to pseudomonas aeruginosa (pg) were studied in acute infections in mice. pg was highly effective in controlling lethal infections induced in mice by the major immunotypes of p. aeruginosa; greater than or equal to 10 microgram of of gamma-globulin per mouse protected against challenge with less than or equal to 10(6) 50% lethal doses of p. aeruginosa. pg wa ... | 1977 | 70492 |
| inhibition of phagocytosis in vitro by obligate anaerobes. | a variety of species of obligate anaerobes have been shown to interfere with the phagocytosis and killing of proteus mirabilis and other aerobic bacteria in vitro. although all the obligate anaerobes examined showed this activity, the effect was greatest with strains of bacteroides melaninogenicus and b. fragilis. in contrast, none of the 36 aerobes tested acted in this way. these observations suggest that the presence of obligate anaerobes may be fundamental to the pathogenesis of some types of ... | 1977 | 73952 |
| stomach as source of bacteria colonising respiratory tract during artificial ventilation. | 10 adults had intermittent positive-pressure ventilation for 3--34 days. all 10 had paralytic ileus. microbial overgrowth in the stomach was found in 9 patients (bacterial in 7 and fungal in 2); gram-negative bacteria predominated. the trachea invariably became colonised by bacteria, mainly gram-negative organisms. in 3 instances the gram-negative bacteria were found in the stomach before they appeared in the tracheal aspirate, and in 1 case the pathogen originated in the faeces. | 1978 | 81991 |
| characterization of murine hepatoma bw7756. ii. comparison of adult, fetal, and neoplastic liver soluble antigens. | 1999 | 84344 | |
| biogenic amines derived from tryptophan in systemic and cutaneous scleroderma. | blood levels of serotonin (5-ht) and urinary excretion of 5-hydroxyindole-acetic acid (5-hiaa), tryptamine (t), and indole-acetic acid (iaa) were determined in 39 cases of systemic scleroderma and in 7 cases of very severe cutaneous scleroderma. the t/iaa ratio was normal and serotonin elevated in mild and rather severe acrosclerosis alike, i.e. in systemic scleroderma with pronounced vascular involvement. the t/iaa ratio was increased and serotonin normal in severe acroscleroderma, representing ... | 1999 | 84460 |
| serum alkaline phosphatase activity in acrodermatitis enteropathica: an index of the serum zinc level. | a significant positive correlation between serum zinc and serum alkaline phosphatase levels was demonstrated in four patients suffering from acrodermatitis enterophathica for which they received oral zinc sulphate therapy. in one of the male patients a significant inverse relation between serum zinc and serum copper was found. | 1999 | 84482 |
| separation of beta2-microglobulin from transfer factor in dialyzable leukocyte extracts. | dialyzable leukocyte extracts prepared according to the original method of lawrence contain 4 x 10(4) molecules of beta2-microglobulin per lymphocyte equivalent. the negative skin test converting biological activity (transfer factor) is separable by means of sephadex g-25 gel chromatography from the beta2-microglobulin component of the extracts. this finding does not support the hypothesis of shifrine and scibienski on beta2-microglobulin being the nonspecific anchor of specific transfer factor ... | 1999 | 84525 |
| factors affecting the fibrinolytic response to surgery. | the stress of injury and surgical operation results in an initial increase in the spontaneous fibrinolytic activity of the blood which is followed by a period of reduced activity in the postinjury or postoperative period. this 'fibrinolytic shutdown' is particularly marked in patients with malignant disease and occurs irrespective of whether or not they develop a deep venous thrombosis. it also occurs in patients with benign disease and in these patients is greater, though only on the first post ... | 1999 | 84546 |
| thyrotoxicosis during pregnancy. | the diagnosis of thyrotoxicosis during pregnancy is difficult on clinical grounds only. the determination of free thyroid hormones or free thyroid hormone indices is important and is possibly supplemented by the trh stimulation test. thyrotoxicosis during pregnancy should always be treated actively. the authors recommend subtotal thyroidectomy if there are indications for surgical therapy (nodular goitre or large diffuse goitre). otherwise treatment with thyrostatic agents is used. after operati ... | 1999 | 84547 |
| [effect of s-adenosyl-l-methionine on the cerebral and peripheral metabolism of l-dopa]. | the repartition of [3h]l-dopa administered i.p. does not change in rats treated with s-adenosyl-l-methionine (sam). the effect was studied on the central nervous system and at the periphery. the biosynthesis of metabolites [3h]dopamine and [3h]3-o-methyldopamine are also unchanged. on the other hand, in the kidney an accumulation of [3h]norepinephrine +[3h]normetanephrine was observed, while in the brainstem + midbrain the synthesis of these metabolites was decreased after sam injection. the rel ... | 1978 | 84550 |
| study of the glycolipid composition of the milk fat-globule membrane and the mouse mammary tumour virus prepared from the milk of infected swiss mice [proceedings]. | 1978 | 84579 | |
| studies on the mechanism of goitrogenic action of diphenylthiohydantoin. | diphenylthiohydantoin (dpth) is a potent goitrogenic compound and produces goiters in rats. like methimazole, dpth depresses plasma t4 and t3 concentrations and elevates plasma t4 and t3 concentrations and elevates plasma tsh concentration. unlike methimazole, however, dpth does not suppress thyroidal radioiodine uptake and thyroid hormone synthesis, although the monoiodotyrosine to diiodotyrosine ration is elevated by dpth. dpth does not inhibit thyroidal radioiodine release or augment the degr ... | 1978 | 84751 |
| [use of chromolymphotrast for color lymphography]. | 1979 | 84768 | |
| the role of algal antigenic determinants in the recognition of potential algal symbionts by cells of chlorohydra. | algal cells grown in the green hydra chlorohydra viridissima were shown to possess characteristic antigenic determinants not found in algae cultured in vitro. these antigenic determinants, including those localized on the algal cell surface, were shown to be responsible for the phagocytic recognition of potential algal symbionts by digestive cells of chlorohydra. the results of this study indicate the existence of two systems governing phagocytosis in chlorohydra, one specific for algal cells gr ... | 1999 | 84815 |
| rapid orthograde and retrograde axonal transport of acetylcholinesterase as characterized by the stop-flow technique. | 1. in rabbit peroneal nerves incubated in vitro at 37 degrees c, acetylcholinesterase (ache) activity accumulated at both borders of a short region cooled to 5 degrees c. accumulation was unaffected by concentrations of cycloheximide that inhibited 86% of local protein synthesis, as measured by the incorporation of [3h]leucine. it is probable that the local changes in enzyme activity during incubation reflected redistribution of the enzyme by axonal transport. 2. ache activity accumulated almost ... | 1978 | 84868 |
| who should measure the blood-pressure? | 1999 | 84917 | |
| a.f.p. and congenital nephrosis finnish type. | 1999 | 84930 | |
| dietary fibre and experimental colon cancer. | 1979 | 85018 | |
| captopril in a hyponatraemic hypertensive: need for caution in initiating therapy. | 1999 | 85145 | |
| [determination of protein-sh groups with ddd reagent]. | 1976 | 85309 | |
| [the efficacy of radiohypophysectomy with yttrium 90 in metastatic breast cancer (author's transl)]. | radiohypophysectomy in 176 women with metastatic breast cancer, treated over the past 20 years, did not prolong life, but relieved pain in almost half of the patients. this procedure can be carried out quickly and without risk even in severly debilitated patients. | 1999 | 85371 |
| [mast-cell degranulation in the intestine: its significance for the pathogenesis of galactosamine hepatitis. histological and histochemical studies on mast-cells using toluidine-blue and subsequent naphthol-asd-chloracetate reaction (author's transl)]. | 1978 | 85385 | |
| [comparative studies on the demonstrability of eosinophilic granuloma using biebrich's scarlet staining and adam's reaction]. | 1999 | 85391 | |
| comparative light- and electron-microscopical study of the normal adenohypophysis in the human. | the pars distalis of 1 girl and of 3 sexually mature women was studied. the glands were dissected out and fixed within a period of 30 min following death; in the aldehyde fixative, each gland was systematically divided into ten pieces. before fixation in osmium tetroxide, each piece was again divided into several blocks. at least 60 blocks were obtained from each gland. semi-thin sections obtained from all the blocks were stained and studied under the light microscope. ultrathin sections were ob ... | 1979 | 85403 |
| [control and prevention of foot and mouth disease in the western hemisphere]. | 1999 | 85453 | |
| eastern association of electroencephalographers, le chantecler, ste. adele, quebec, canada, march 2--5, 1978. abstracts. | 1999 | 85518 | |
| the spinal cord protein (scp): appraisal of physiological and immunological hypotheses of anti-encephalitogenic action. | 1978 | 85602 | |
| epidermal cytoplasmic antigens. | 1999 | 85677 | |
| in vitro synthesis of infectious transforming dna by the avian sarcoma virus reverse transcriptase. | infectious dna molecules, capable of transforming chicken embryo fibroblasts, can be synthesized by the rous sarcoma virus-associated reverse transcriptase in vitro. the optimal enzymatic conditions employed for infectious dna synthesis also facilitate maximum synthesis of genome length dna. analysis of the dna product synthesized by detergent-disrupted rous sarcoma virus under these conditions indicates that dna complementary to viral rna (minus-strand dna) is genome length in size, whereas dna ... | 1979 | 85719 |
| [method of preparing the tularemia antigen for an erythrocyte diagnosticum]. | 1979 | 85742 | |
| [work of the clinical diagnostic laboratories of rural district hospitals in the belorussian ssr]. | 1999 | 85759 | |
| a review of the evidence for methadone maintenance as a treatment for narcotic addiction. | 1999 | 85827 | |
| low plasma-25-hydroxyvitamin d without osteomalacia. | 1999 | 85831 | |
| test of a novel method for analysis of the efficacy of antihypertensive drugs. | diastolic blood-pressure data from 42 published studies, representing 23 anti-hypertensive drug regimens and 971 patients, were used to test the hypothesis that there is a linear relation between pretreatment diastolic pressure (p.t.d.p.) and the drug-induced fall in pressure (deltad.p.), such that the "ideal-response line" relating these variables has a slope=1.0 and intercepts the p.t.d.p. axis at 90 mm hg. most of the regimens failed to show ideal behaviour; slopes of the regression lines wer ... | 1999 | 85882 |
| urinary beta 2 microglobulin in upper and lower urinary-tract infections. | beta 2-- microglobulin excretion in 24 h urine collections and beta2- microglobulin clearance were significantly increased in patients with upper-urinary-tract infections, but beta 2- microglobulin clearance and excretion were normal in patients with cystitis. beta 2-microglobulin estimation may be used to distinguish between upper and lower urinary-tract infections, except when pre-existing tubular damage is present. voided urine must have a ph above 6 . 0, since beta 2- microglobulin is rapidl ... | 1979 | 86044 |
| [clinical results with granulocyte transfusion (author's transl)]. | 16 adult patients with granulocytopenia and septicemia resistant to antibiotics received 42 granulocyte transfusions. the granulocytes were obtained from healthy donors with a blood cell separator by continuous flow centrifugation. adding hydroxyethyl-starch an average of 1.8 x 10(10) leukocytes with 69% granulocytes were harvested in 3.5 hours. a small leukocyte increment after the transfusion was seen in half of the recipients. no correlation could be found between fever lysis and survival of ... | 2000 | 86150 |
| demonstration of rheumatoid factor idiotypic antigens on peripheral blood b and t lymphocytes from patients with rheumatoid arthritis. | antisera were raised against three polyclonal igm rheumatoid factors (rf). after adequate absorptions, the antisera were rendered idiotype-specific, as assayed by haemagglutination technique. by using the anti-idiotype antisera in indirect immunofluorescence on peripheral blood lymphocytes from the patients used as donors for the immunizing rf, it was demonstrated that 3-14% of the lymphocytes were stained, and thus had membrane-bound structures with idiotypic antigens similar to those of the ci ... | 2000 | 86203 |
| the humoral and cell-mediated immune responses to somatic and metabolic antigens in rats infected with angiostrongylus cantonensis. | 1978 | 86211 | |
| allo-anti-c in a patient who had previously made an autoantibody mimicking anti-c. | a patient, previously studied by us, who had produced a benign autoantibody with a specificity that mimicked anti-c, has now produced allo-anti-c that is not of the mimicking type. she is no longer producing any serologically demonstrable autoantibody. it is highly probable that conversion from auto to alloantibody production in this patient was prompted by the introduction of additional foreign immunogen on fetal red blood cells during her third pregnancy. | 2000 | 86216 |
| [intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera]. | the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ... | 1978 | 86237 |
| serological investigations on ribitol-containing lipopolysaccharides from proteus mirabilis. | lipopolysaccharides containing or noncontaining ribitol derived from several proteus mirabilis strains were studied using passive hemagglutination, hemagglutination-inhibition and semi-quantitative precipitin tests. the results indicate that ribitol plays a role in the serological specificity of the respective lipopolysaccharides. | 1978 | 86334 |
| the role of lysine in the serological specificity of some proteus mirabilis lipopolysaccharides. | 1978 | 86335 | |
| serological abnormalities in families of patients with rheumatoid arthritis: eight to twelve years follow-up study. | serum gammaglobulin level, the presence of rheumatoid factor and of anti-nuclear antibodies were re-examined after 8 to 12 years in families of 21 seropositive rheumatoid arthritis patients. in the time 8 members of the families developed rheumatoid arthritis and the number of persons with elevated serum gammaglobulins increased. rheumatoid tests yielded variable results. no relationship could be demonstrated between development of disease symptoms and the earlier presence of rheumatoid factor. | 2000 | 86342 |
| the effect of uremia and dialysis on cell-mediated immunity. | delayed-type hypersensitivity to ppd, two types t rosettes as well as lymphokine production were studied in patients with end-stage renal failure maintained on hemodialysis. a significant impairment of skin reactivity and the lowering of the number of t cells were found, while no definite changes of lymphokine production were detected. no conclusive data are obtained as to the role of hemodialysis in reversing of immunologic deficits noted in uremia. | 2000 | 86344 |
| the isolated human cortex. a golgi analysis of krabbe's disease. | the clinical course of a child with krabbe's leukodystrophy was characterized by clinical seizures, startle myoclonus, and paroxysmal activity recorded by eeg. at autopsy in the fourth year, myelinated subcortical axons were destroyed, virtually completely. despite isolation from major subcortical and interhemispheric connections, the cell and fiber pattern of the cortex appeared remarkably normal in routine histologic preparations. the normal range of pyramidal and stellate interneurons were al ... | 1979 | 86346 |
| inhibition of neuronal firing by opiates: evidence against the involvement of cyclic nucleotides. | 1. extracellular recordings were made in vitro from single neurones of the myenteric plexus of the guinea-pig ileum. 2. neuronal firing was inhibited by morphine and normorphine (10 nm to 1 micrometer). cyclic adenosine 3',5'-monophosphate (cyclic amp) (100 micrometer to 1 mm) also inhibited the firing of the majority of the neurones. prostaglandin e2 usually caused a short-lasting excitation of myenteric neurones and the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine was usually withou ... | 1979 | 86371 |
| 270-mhz nuclear-magnetic-resonance study on linear gramicidin a in dimethylsulfoxide. a new interpretation. | on the basis of the finding of two sets of coupling constants (8.8 hz and 6.7 hz) in the 270-mhz proton magnetic resonance spectra of linear gramicidin in dimethylsulfoxide and the comparison of its infrared spectrum with those of known conformations of alternating poly(gamma-benzyl-d-glutamate--gamma-benzyl-l-glutamate), it is proposed that the antibiotic has an ld-ribbon structure. | 2000 | 86442 |
| the phenomenon of differentiation in murine erythroleukemic cells. | 1978 | 86529 | |
| cytofluorometric and cytochemical comparisons of normal and abnormal human cells from the female genital tract. | acridine orange staining of exfoliated cells from epithelial tissues facilitates discrimination between normal and abnormal cells: abnormal cells develop highly elevated nuclear fluorescence. comparisons of acridine orange (ao) staining with propidium iodide (pi) or feulgen staining have shown that: (a) pi staining also provides highly elevated nuclear fluorescence from abnormal cells; (b) the distributions of nuclear fluorescence following ao or pi staining were usually not significantly differ ... | 1979 | 86579 |
| interactions between pairs of dna-specific fluorescent stains bound to mammalian cells. | the interactions between dna-specific fluorescence stains complexed with mitotic chinese hamster cells were studied by spectrofluorometric and flow fluorometric techniques. the degree of binding interactions and of energy transfer between stains was determined from the intensities and shapes of fluorescence emission spectra of cells complexed with pairs of stains. the stain pairs hoechst 33258-chromomycin a3, hoechst 33258-ethidium bromide, and chromomycin a3-ethidium bromide exhibited efficient ... | 2000 | 86583 |
| acriflavine-feulgen stilbene staining: a procedure for automated cervical cytology with a television based system (leytas). | a sample preparation and staining procedure for automated cytology with a tv based system (leytas) is described. it consists of a centrifugation technique and automated acriflavine-feulgen stilbene staining of cervical specimens. the advantages of using both the fluorescence and the absorption image of acriflavine-feulgen stilbene stained cervical cells for a television based system are discussed. | 2000 | 86584 |
| ultrastructure of bacteroides species: bacteroides asaccharolyticus, bacteroides fragilis, bacteroides melaninogenicus subspecies melaninogenicus, and b. melaninogenicus subspecies intermedius. | representative strains of two subspecies of bacteroides melaninogenicus (subspecies melaninogenicus and subspecies intermedius) and bacteroides asaccharolyticus as well as b. asaccharolyticus strain 536b isolated from a human perirectal abscess and bacteroides fragilis atcc 25285 were examined by glutaraldehyde-osmium fixation, ruthenium red fixation and staining, and thorium hydroxyde staining as well as by the physical preparative techniques of critical point drying--transmission electron micr ... | 1979 | 86590 |
| the results of prostatectomy: a symptomatic and urodynamic analysis of 152 patients. | there were 152 patients with prostatism investigated by inflow cystometry and pressure flow analysis of micturition before and after elective prostatectomy. many symptoms attributed to obstruction were found to be owing to bladder instability, which was demonstrated in 60 per cent of the patients. the symptomatic improvement postoperatively was accompanied by a decrease in the incidence of instability to 25 per cent. the repeat urodynamic studies and symptom analysis demonstrated a surgical succ ... | 2000 | 86617 |
| research into lead pollution. | 2000 | 86732 |