Publications

cloned cdna of a/swine/iowa/15/1930 internal genes as a candidate backbone for reverse genetics vaccine against influenza a viruses.	reverse genetics viruses for influenza vaccine production usually utilize the internal genes of the egg-adapted a/puerto rico/8/34 (pr8) strain. this egg-adapted strain provides high production yield in embryonated eggs but does not necessarily give the best yield in mammalian cell culture. in order to generate a reverse genetics viral backbone that is well-adapted to high growth in mammalian cell culture, a swine influenza isolate a/swine/iowa/15/30 (h1n1) (rg1930) that was shown to give high y ...	2012	22230579
factors associated with highly pathogenic avian influenza h5n2 infection on table-egg layer farms in the midwestern united states, 2015.	a case-control study was conducted among commercial table-egg layer and pullet operations in iowa and nebraska, united states, to investigate potential risk factors for infection with highly pathogenic avian influenza (hpai) h5n2. a questionnaire was developed and administered to 28 case farms and 31 control farms. data were collected at the farm and barn levels, enabling two separate analyses to be performed-the first a farm-level comparison of case farms vs. control farms, and the second a bar ...	2016	27309288
case series of turkey farms from the h5n2 highly pathogenic avian influenza outbreak in the united states during 2015.	between december 2014 and june 2015, an outbreak of h5n2 hpai caused the largest and most expensive agriculture emergency in u.s. department of agriculture-animal and plant health inspection service history. the outbreak affected 21 states; 232 poultry farms (211 commercial and 21 backyard) were affected, and approximately 49.6 million birds were depopulated on poultry farms. the majority of affected farms were commercial turkey operations (n = 160). this report is a case series describing 104 h ...	2016	27309289
outbreak of h5n2 highly pathogenic avian influenza a virus infection in two commercial layer facilities: lesions and viral antigen distribution.	the largest outbreak of highly pathogenic avian influenza a virus (hpaiv) infection in u.s. history began in december 2014 resulting in the euthanasia of millions of birds and collateral economic consequences to the u.s. poultry industry. we describe 2 cases of h5n2 hpaiv infection in laying hens in iowa. following a sharp increase in mortality with minimal clinical signs, 15 dead birds, from 2 unrelated farms, were submitted to the iowa state university veterinary diagnostic laboratory. common ...	2016	27423731