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[ivermectin].initial clinical trials in 1980 showed that ivermectin was remarkably effective against onchocerca volvulus. some 25 years after more than 50 million people are treated annually with mectizan mainly within the framework of the african programme for onchocerciasis control (apoc). this success has been possible thanks to merck mectizan donation program and to distribution through a novel strategy based on the strong involvement of endemic communities. in the last few years mectizan has been used i ...200515903082
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