Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| pathogenesis of two strains of lion (panthera leo) morbillivirus in ferrets (mustela putorius furo). | canine distemper virus (cdv) was previously considered to have a host range restricted to the canid family. in 1994, the virus was associated with sporadic outbreaks of distemper in captive felids. however, after severe mortality occurred in the serengeti lions (panthera leo), attention became focused on the pathogenesis of the virus and a concerted effort was made to identify the virus as cdv or a closely related feline morbillivirus. the present study was designed to explore the susceptibility ... | 2001 | 11355661 |
| feline morbillivirus, a previously undescribed paramyxovirus associated with tubulointerstitial nephritis in domestic cats. | we describe the discovery and isolation of a paramyxovirus, feline morbillivirus (fmopv), from domestic cat (felis catus). fmopv rna was detected in 56 (12.3%) of 457 stray cats (53 urine, four rectal swabs, and one blood sample) by rt-pcr. complete genome sequencing of three fmopv strains showed genome sizes of 16,050 bases, the largest among morbilliviruses, because of unusually long 5' trailer sequences of 400 nt. fmopv possesses identical gene contents (3'-n-p/v/c-m-f-h-l-5') and is phylogen ... | 2012 | 22431644 |
| existence of feline morbillivirus infection in japanese cat populations. | feline morbillivirus (fmopv) is a member of a new virus species that has only been found in the hong kong cat population. for the first time, however, we have now detected nucleotide sequences similar to fmopv in samples from japanese cat populations. the positive rates for urine and blood samples from japanese cats were 6.1 % (5/82) and 10 % (1/10), respectively. these sequences are similar to the previously reported fmopv, with 92-94 % identity, and substantially different from all other morbi ... | 2014 | 23929233 |
| genetic diversity of feline morbilliviruses isolated in japan. | feline morbillivirus (fmopv) is an emerging virus in domestic cats and considered to be associated with tubulointerstitial nephritis. although fmopv was first described in china in 2012, there has been no report of the isolation of this virus in other countries. in this report, we describe the isolation and characterization of fmopv from domestic cats in japan. by using reverse transcription (rt)-pcr, we found that three of 13 urine samples from cats brought to veterinary hospitals were positive ... | 2014 | 24728711 |
| identification of a natural recombination in the f and h genes of feline morbillivirus. | feline morbillivirus (fmopv) has recently been identified in hong kong and japan. fmopv is considered to belong to the genus morbillivirus, in the family paramyxoviridae. in this study, the complete nucleotide sequences of three strains of fmopv detected in cats in japan were determined. among the six genes in fmopv; n, p/v/c, m, f, h and l, the p gene showed the highest polymorphism in the nucleotide and putative amino acid sequences among the fmopv strains. there was no geographical associatio ... | 2014 | 25262470 |
| basic biological characterization of feline morbillivirus. | feline morbillivirus (fmopv) is an emerging virus that was recently discovered in domestic cats with chronic nephritis. despite the potential role of fmopv in chronic nephritis, little is known about its biological characteristics. in this study, we established a quantitative assay of fmopv by using an indirect immunofluorescence technique. viral titers of fmopv were determined in one week. treatment with polybrene® or trypsin which was previously used in virus isolation did not augment the viru ... | 2015 | 25649267 |
| in vitro host range of feline morbillivirus. | feline morbillivirus (fmopv) is an emerging virus in cats, which is associated with tubulointerstitial nephritis. to study the in vitro host range of fmopv, we inoculated fmopv strain ss1 to 32 cell lines originated from 13 species and cultured for 2 weeks, followed by rna extraction and reverse-transcription-polymerase chain reaction for fmopv detection. as a result, only cell lines derived from cats and african green monkeys were susceptible to fmopv. fmopv infects diverse feline cell lines: e ... | 2015 | 26027844 |
| quantitative pcr detection of feline morbillivirus in cat urine samples. | feline morbillivirus (fmopv) is a new virus species and its detection is important, since correlation has been reported between fmopv virus infection and tubulointerstitial nephritis in cats. here, we report a real-time reverse transcription (rt)-pcr system that can detect the fmopv l-gene sequence with more than 10-time higher sensitivity than a conventional pcr system, resulting in detection of less than 10 copies of the template dna. the total fmopv positive rate of urine samples from veterin ... | 2016 | 26227478 |
| rapid detection of feline morbillivirus by a reverse transcription loop-mediated isothermal amplification. | feline morbillivirus (fmopv) is an emerging virus in domestic cats and considered to be one of the causes of chronic renal failure in cats. in this study, we established a reverse transcription loop-mediated isothermal amplification (rt-lamp) assay for the detection of fmopv. the results indicated that the detection limit of the assay was 10 50% tissue culture infective dose (tcid50)/ml in the original sample, and sensitivity of the assay was calculated as 0.12 tcid50 per one rt-lamp reaction. w ... | 2016 | 26268665 |
| first report of feline morbillivirus in europe. | feline morbillivirus was detected in urine samples of a 15 year old cat suffering from severe nephropathy. viral rna was not detected in blood and faecal samples and also the most common pathogens associated to cat kidney failure were not found. this report describes the first evidence of feline morbillivirus in europe. | 2015 | 26269317 |
| chronic infection of domestic cats with feline morbillivirus, united states. | 2016 | 26982566 | |
| genome characterization of feline morbillivirus from italy. | feline morbillivirus (femv) has been recently identified by rt-pcr in the urine sample of a nephropathic cat in italy. in this report, we describe the whole genome sequence of strain piuma/2015 obtained by combination of sequence independent single primer amplification method (sispa) and next generation sequencing (ngs) starting from rna purified from the infected urine sample. the existence in germany and turkey of femvs from cats divergent from piuma/2015, suggests the presence of femv heterog ... | 2016 | 27155238 |
| epidemiological and pathological study of feline morbillivirus infection in domestic cats in japan. | feline morbillivirus (fmopv) is a novel paramyxovirus found to infect domestic cats. fmopv has been isolated in several countries in asia and europe and is considered to have genetic diversity. also, it is suspected to be associated with feline renal diseases including tubulointerstitial nephritis (tin), which affects domestic cats with a high incidence rate. | 2016 | 27724851 |
| first report of feline morbillivirus in south america. | feline morbillivirus was first identified in healthy and diseased stray cats captured in hong kong. recently, it was demonstrated that the virus circulates within cat populations in japan, italy, germany, and the usa. importantly, an association between feline morbillivirus infection and chronic kidney disease was suggested by histological analysis of kidney tissue of infected cats. the aim of this study was to verify the presence and examine the genetic diversity of feline morbilliviruses assoc ... | 2017 | 27804021 |
| frequency, clinicopathological features and phylogenetic analysis of feline morbillivirus in cats in istanbul, turkey. | objectives the aim of the study was to investigate feline morbillivirus (fmopv) frequency, phylogeny and associated pathology in cats in istanbul, turkey. methods samples from sick (n = 96) and dead ( n = 15) cats were analysed using reverse transcription pcr. blood and urine analyses and histopathology were also performed. results fmopv rna was detected in six cats (5.4%), including three sick (in the urine) and three dead cats (tissues). a significantly greater proportion of fmopv rna-positive ... | 2017 | 28112564 |
| development of an elisa for serological detection of feline morbillivirus infection. | feline morbillivirus (femv), a member of the family paramyxoviridae, is an emerging virus that was discovered in 2012. despite the importance of femv infection in cats because of its postulated involvement in kidney diseases, no simple serological assay has been reported in its detection. here, femv phosphoprotein (p protein) was expressed and purified as a glutathione-s-transferase (gst)-fusion protein and used for an enzyme-linked immunosorbent assay (elisa) to detect femv-specific antibodies. ... | 2017 | 28470418 |
| discovery and current research status of feline morbillivirus. | feline morbillivirus (femv) is an emerging virus that was first discovered in hong kong in 2012. femv is epidemiologically associated with kidney and other lower urinary tract diseases in cats. phylogenetic analysis of its genome sequence indicates that femv is the most closely related to the members of genus morbillivirus, although femv is relatively distant in the phylogenetic analysis, and its target tissues and pathogenicity are different from the other members of the genus. the origin and r ... | 2016 | 29081466 |
| molecular detection and characterisation of feline morbillivirus in domestic cats in malaysia. | feline morbillivirus (femv), a novel virus from the family of paramyxoviridae, was first identified in stray cat populations. the objectives of the current study were to (i) determine the molecular prevalence of femv in malaysia; (ii) identify risk factors associated with femv infection; and (iii) characterise any femv isolates by phylogenetic analyses. molecular analysis utilising nested rt-pcr assay targeting the l gene of femv performed on either urine, blood and/or kidney samples collected f ... | 2019 | 31500720 |
| feline morbillivirus, a new paramyxovirus possibly associated with feline kidney disease. | feline morbillivirus (femv) was first isolated in stray cats in hong kong in 2012. since its discovery, the virus has been reported in domestic cats worldwide, including in hong kong, japan, italy, us, brazil, turkey, uk, germany, and malaysia. femv is classified in the morbillivirus genus within the paramyxoviridae family. femv research has focused primarily on determining the host range, symptoms, and characteristics of persistent infections in vitro. importantly, there is a potential associat ... | 2020 | 32370044 |
| early renal involvement in cats with natural feline morbillivirus infection. | feline morbillivirus (femv) is a newly discovered paramyxovirus infecting domestic cats and its role in the pathogenesis of feline chronic kidney disease (ckd) has been suggested, however not confirmed. the primary aim of the study was to evaluate the renal damage associated with femv infection in cats. in this retrospective study, clinical and clinicopathological data were compared among 14 femv naturally infected, 21 ckd and 22 healthy cats. femv positive cats had serum chemistry analytes and ... | 2020 | 32397661 |
| molecular epidemiology and genome analysis of feline morbillivirus in household and shelter cats in thailand. | feline morbillivirus (femv) has been discovered in domestic cats associated with tubulointerstitial nephritis, but femv is also detected in healthy cats. this research aimed to identify and characterize the femv strains detected in a thai cat population. | 2020 | 32660481 |
| feline morbillivirus infection associated with tubulointerstitial nephritis in black leopards (panthera pardus). | feline morbillivirus (femv) is an emerging rna virus in the paramyxoviridae family that was recently discovered in domestic cats (felis catus). to date, 2 genotypes (femv-1 and femv-2) have been detected in cats from various countries, and femv-1 is recognized as a pathogen associated with nephritis. however, information regarding the pathological roles and potential transmission to other felids is limited. in this article, we describe the identification of femv in 2 black leopards (panthera par ... | 2020 | 32830605 |
| feline morbillivirus in northwestern italy: first detection of genotype 1-b. | a novel morbillivirus was recently described in stray and domestic cats in asia, the usa and europe. most cats infected with feline morbillivirus (femv) showed lower urinary tract or kidney disease. although the association of femv infection and kidney diseases has been suggested, the virus pathogenicity remains unclear. the present study aimed to investigate the distribution of femv infection, as well as the relationship between femv infection and kidney diseases in cats from northwestern italy ... | 2020 | 33140998 |
| high seroprevalence of feline morbilliviruses in free-roaming domestic cats in chile. | feline morbillivirus infections have gained increased attention due to repeated reports of their association with urinary tract disease in cats. in the present study, 112 serum samples from free-roaming domestic cats in chile were tested for antibodies against feline morbillivirus genotypes 1 and 2 (femv-1 and femv-2) using an indirect immunofluorescence assay. in total, 63% of the animals showed antibodies against one or both femv genotypes. antibodies directed exclusively against femv-2 were s ... | 2020 | 33216214 |
| identification of novel feline paramyxoviruses in guignas (leopardus guigna) from chile. | the family of paramyxoviruses has received growing attention as several new species have been identified recently, notably two different clusters in domestic cats, designated as feline morbillivirus (femv) and feline paramyxovirus (fpav). their phylogenetic origin and whether wild felids also harbor these viruses are currently unknown. kidney samples from 35 guignas (leopardus guigna), a wild felid from chile, were investigated for paramyxoviruses using consensus-rt-pcr. in addition, thirteen se ... | 2020 | 33291219 |
| high genetic diversity of paramyxoviruses infecting domestic cats in western brazil. | feline morbillivirus was discovered in 2012 in cats from hong kong, and it was initially found to be associated with chronic kidney disease. although subsequent molecular surveys showed a common occurrence in cat populations from distinct countries, there were controversial results regarding the relationship between viral shedding through urine and reduced kidney function. in this study, 276 domestic cats of diverse origins from western brazil had their urine evaluated for the presence of paramy ... | 2020 | 33295141 |
| molecular characterization of feline paramyxovirus and feline morbillivirus in cats from brazil. | this study is aimed at detecting feline paramyxovirus (fpav) and feline morbillivirus (femv) in 35 urine samples from domestic cats, collected in 2019, with or without clinical signs of uropathies using a reverse transcription-polymerase chain reaction (rt-pcr) followed by semi-nested polymerase chain reaction (sn-pcr) assays to amplify a partial paramyxovirus l gene. eight (22.9%) out of the 35 urine samples were positive for paramyxoviruses. sequencing and phylogenetic analyses revealed that t ... | 2021 | 33483894 |
| cerebral cysticercosis in a wild bengal tiger (panthera tigris tigris) in bhutan: a first report in non-domestic felids. | the endangered bengal tiger (panthera tigris tigris) is a keystone species playing an essential role in ecology as well as in the social and spiritual lives of the himalayan people. the latest estimate of the bengal tiger population in bhutan accounts for 103 individuals. infectious organisms, including zoonotic parasites causing high burden in human health, have received little attention as a cause of mortality in tigers. taeniosis/cysticercosis, caused by the cestode taenia solium, is consider ... | 2021 | 33665082 |
| seroprevalence of infection with feline morbilliviruses is associated with flutd and increased blood creatinine concentrations in domestic cats. | feline morbilliviruses (femv) are fairly newly discovered paramyxoviruses found in cats. the first description indicated an association with widely distributed chronic kidney disease (ckd) in the host species. in various studies, a global prevalence and a further genotype, designated femv-2, and the involvement of other organ systems in infected individuals were shown. using an immunofluorescence assay, we detected an overall seroprevalence of femv in almost half of the cats investigated (n = 38 ... | 2021 | 33808115 |
| first detection of feline morbillivirus infection in white-eared opossums (didelphis albiventris, lund, 1840), a non-feline host. | feline morbillivirus (femv) was first detected in 2012 in domestic cats from hong kong and was found to be associated with tubulointerstitial nephritis and chronic kidney disease. in subsequent studies in other countries, femv was detected in asymptomatic cats. however, it is not clear whether femv plays a role as a pathogen in the kidney diseases of cats, and other epidemiological data are still unknown. to date, studies have reported the presence of femv exclusively in domestic cats. this stud ... | 2021 | 33872470 |
| feline morbillivirus infection in domestic cats: what have we learned so far? | feline morbillivirus (femv) was identified for the first time in stray cats in 2012 in hong kong and, since its discovery, it was reported in domestic cats worldwide. although a potential association between femv infection and tubulointerstitial nephritis (tin) has been suggested, this has not been proven, and the subject remains controversial. tin is the most frequent histopathological finding in the context of feline chronic kidney disease (ckd), which is one of the major clinical pathologies ... | 2021 | 33921104 |
| feline morbillivirus-1 in dogs with respiratory diseases. | feline morbillivirus-1 (femv-1) is a viral pathogen associated with kidney disease in domestic cats and wild felids. we initially identified the femv-1 from the lung of a necropsied dog with severe pulmonary disease by the reverse transcription polymerase chain reaction (rt-pcr). thereafter, we investigated femv-1 in nasal and oral swab samples from 73 healthy and 113 dogs with respiratory illnesses. we found polymerase chain reaction (pcr)-positive femv-1 from only 14/113 (12.39%) dogs with res ... | 2021 | 34355534 |