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madariaga virus infection associated with a case of acute disseminated encephalomyelitis.we present the first report of a pediatric case of acute disseminated encephalomyelitis (adem) associated with madariaga virus infection (madv, alphavirus, togaviridae; formerly known as south american variants of eastern equine encephalitis virus [eeev]) in a patient of the 2010 alphaviral epidemic reported in panama. the patient was admitted to the hospital del niño in panama city with suspected meningitis, exhibited with decreased alertness and disorientation in space and time, hemiparesis, a ...201525870420
isolation and characterization of madariaga virus from a horse in paraíba state, brazil.madariaga virus (madv), the new species designation for the south american isolates of eastern equine encephalitis virus (eeev), is genetically divergent and substantially different in ecology and pathogenesis from north american eeev strains. we isolated and characterized a madv isolate obtained from a horse in brazil. our results support previous phylogenetic studies showing there are three genetically distinct madv lineages. the madv isolate from paraíba state belongs to the south american li ...201526608567
epidemiology of emergent madariaga encephalitis in a region with endemic venezuelan equine encephalitis: initial host studies and human cross-sectional study in darien, panama.neurotropic arboviral infections are an important cause of encephalitis. a zoonotic, vector-borne alphavirus, madariaga virus (madv; formerly known as south american eastern equine encephalitis virus), caused its first documented human outbreak in 2010 in darien, panama, where the genetically similar venezuelan equine encephalitis virus (veev) is endemic. we report the results of a seroprevalence survey of animals and humans, illustrating contrasting features of madv and veev ecology and epidemi ...201627101567
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