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frequency of hla antigens in chronic myelocytic leukemia.histocompatibility antigen (hla) phenotypes of 34 patients with ph1+ chronic myelogenous leukemia (cml) were evaluated for association with hla antigens. two control populations were compared to the cml patients: 142 normal volunteer platelet donors, and 160 normal donors of granulocyte transfusions. hla typing was done by lymphocyte microcytotoxicity tests for nine antigens on sublocus a and 15 antigens on sublocus b. hla-b7 and hla-b12 were decreased in cml patients compared to both platelet a ...197769321
co-circulation of two influenza a (h3n2) antigenic variants detected by virus surveillance in individual communities.from march through june 1977 a total of 31 influenza a (h3n2) viruses were isolated from students with respiratory disease who were seen at the student health service on the berkeley campus of the university of california, and 32 influenza a (h3n2) viruses were isolated from persons who participated in a city-wide febrile respiratory disease surveillance program in seattle. the antigenic specificity of the hemagglutinin was determined for each isolate by hemagglutination inhibition testing with ...197883107
tuberculosis in nonhuman primates as a threat to humans.nonhuman primates are used in many laboratories either as modest systems for studies of disease processes or as a source of these tissues for cell culture and vaccine production. much too frequently, the health of these donor animals is taken for granted, although t.b. testing is one of the few procedures routinely performed. in spite of this screening, outbreaks of t.b. among various simian species are still sufficiently commonplace to make maintenance and use of these animals a continuing sour ...1978111982
comparison of human rotavirus disease in tropical and temperate settings.human rotaviruses (hrv) are a common cause of acute nonbacterial gastroenteritis in pediatric patients. a prospective study of hrv disease in a temperate (dallas) and a tropical (san jose, costa rica) setting demonstrated differences in seasonal distribution. in both locales, hrv accounted for 50% to 60% of acute nonbacterial gastroenteritis episodes from december through february; this period corresponded to the cooler months of winter in dallas and to the dry season in san jose. during the res ...1978210656
failure of indicator bacteria to reflect the occurrence of enteroviruses in marine waters.the results of several studies conducted along the upper texas gulf coast, where a substantial amount of quantitative virological data were collected, are compared to bacteriological indicators and other environmental factors on a statistical basis. variables common to all these studies were anlayzed by multivariate regression. although multivariate analysis indicated that the number of viruses detected in water was related to rainfall, salinity, and total coliforms in the water, the amount of v ...1979228561
epidemic renal transplant rejection associated with influenza a victoria.1) iav infection seems to trigger acute renal allograft rejection frequently, especially in the first few months post-transplant, and these rejections are severe with a high rate of ultimate graft loss; 2) seroconversion occurred in most cases despite high dose steroids; 3) the course of iav was prolonged and associated with a high incidence of complications in patients on high dose steroids.1978386316
an epizootiologic study of anthrax in falls county, texas.in june and july, 1974, an anthrax epizootic in falls county, texas, resulted in the death of 236 animals (228 cattle, 5 horses, 2 mules, and 1 pig) on 48 premises. death rates were highest for horses (18.2%) and bulls (16.8%). the epizootic was apparently precipitated by drought, and infection appeared to be the result of ingesting intrinsically contaminated soil and grass. human illness was not associated with the epizootic.1977401803
naturally occurring trypanosomiasis (chagas' disease) in dogs.nine fatal cases of canine american trypanosomiasis (chagas' disease) were encountered from november, 1972, through november, 1975. of the 9 cases, 7 occurred in dogs from 5 central texas counties, and all but one case was diagnosed during the months of september, october, or november. the source of infection was discovered in only one case--that being a doghouse heavily infested with triatoma lectularius occulta. each of 6 bugs collected had infective forms of the protozoan, trypanosoma cruzi. ...1977407202
influenza 1978.during january and february 1978, an outbreak of respiratory infection occurred at fort sam houston, texas. both influenza a/texas and a/ussr were isolated in the hospitalized patients. two different strains of influenza a have not previously been documented during a single outbreak. this raises the possibility of recombination with emergence of a new antigenic strain.1979424791
the costs of an institutional review board.the institutional review board (irb) at the university of texas health science center at san antonio is charged with the responsibility of review of all protocols involving human subjects in research. a large medical institution has many clinical protocols requiring review. the review of hundreds of protocols per year requires much time from the irb staff, the committees which review the protocols, and the investigators who prepare them. this cost is borne by the institution. additional federal ...1979430531
phencyclidine (angel dust) invades texas. 1979451944
influenza surveillance by age and target group.surveillance for influenza virus infections began in mid-1976, continued through three small influenza a outbreaks (mixed a/victoria and a/texas outbreaks in spring, 1977, and winter, 1977-1978 and an a/ussr outbreak peaking in march, 1978). nasopharyngeal specimens were collected for virus isolation from febrile respiratory disease patients coming from four sources: 1) the sunday walk-in clinic of the group health cooperative of puget sound; 2) 200 families under continuous surveillance for res ...1979453178
an outbreak of influenza aboard a commercial airliner.a jet airliner with 54 persons aboard was delayed on the ground for three hours because of engine failure during a takeoff attempt. most passengers stayed on the airplane during the delay. within 72 hours, 72 per cent of the passengers became ill with symptoms of cough, fever, fatigue, headache, sore throat and myalgia. one passenger, the apparent index case, was ill on the airplane, and the clinical attack rate among the others varied with the amount of time spent aboard. virus antigenically si ...1979463858
evaluation of the relationship of sodium in drinking water and toxemia of pregnancy.this study is a retrospective case comparison analysis of the relationship of water-borne na+ and toxemia of pregnancy as a part of a continuous investigation at our facility on the role of various water constituents in human chronic disease. five hundred thirty-seven toxemic pregnant women delivered at jefferson davis hospital, houston, texas, during 1976 were matched by age, race, obstetrical history, and month of delivery to 537 non-toxemic controls. sodium concentration in each patient's dri ...1979474848
zoonotic diseases in psittacine birds: apparent increased occurrence of chlamydiosis (psittacosis), salmonellosis, and giardiasis.between september 1977 and november 1978, chlamydiosis (psittacoisis) was diagnosed in 52 of 128 parrots, 5 of 12 cockatiels, 2 of 5 cockatoos, 3 of 6 macaws, 1 of 22 conures, 2 of 18 lovebirds, and 6 of 76 parakeets; 2 lories and 1 lorikeet were chlamydiosis negative. two cases of human chlamydiosis were associated with two submissions of parrots subsequently found to have active infection. twenty parrots (including 13 that were chlamydiosis positive), 2 cockatiels, 1 macaw, 1 lorie, and 1 para ...1979500464
laboratory-based surveillance of influenza virus in the united states during the winter of 1977-1978. i. periods of prevalence of h1n1 and h3n2 influenza a strains, their relative rates of isolation in different age groups, and detection of antigenic variants.influenza a (h3n2) viruses were isolated from outbreaks and epidemics of disease during the period december 1977 to march 1978. for the last two months of this period, h1n1 strains of influenza a were also responsible for epidemics. in some regions (e.g., hawaii) co-circulation of h1n1 and h3n2 strains occurred, whereas in other regions (e.g., wisconsin) isolation of h3n2 strains had almost ceased prior to isolation of h1n1 strains. few influenza b isolates were reported. analysis of the ages of ...1979507036
laboratory-based surveillance of influenza virus in the united states during the winter of 1977--1978. ii. isolation of a mixture of a/victoria- and a/ussr-like viruses from a single person during an epidemic in wyoming, usa, january 1978.at a time when outbreaks and sporadic cases of influenza caused a a/victoria/3/75-like and a/texas/1/77-like h3n2 strain of influenza were occurring in the rocky mountain region of the usa, about 60% of the students of a high school in cheyenne, wyoming, were involved in an outbreak of influenza-like illness. six influenza a(h1n1) virus isolates were obtained from throat swabs collected from 12 of these students. virus isolated from a seventh student, however, contained a mixture of h1 and h3 (a ...1979507037
advocaté-protegé: pairings and activities in three citizen advocacy programs. 1979542117
isolation of the etiological agent of primary amoebic meningoencephalitis from artifically heated waters.to determine whether artificial heating of water by power plant discharges facilitates proliferation of the pathogenic free-living amoebae that cause primary amoebic meningoencephalitis, water samples (250 ml) were taken from discharges within 3,000 feet (ca. 914.4 m) of power plants and were processed for amoeba culture. pathogenic naegleria fowleri grew out of water samples from two of five lakes and rivers in florida and from one of eight man-made lakes in texas. pathogenic n. fowleri did not ...1977596872
raw hamburger: an interstate common source of human salmonellosis.an interstate common-source outbreak of salmonellosis was first detected in the united states in september and october, 1975, when a tenfold increase in salmonella newport isolates was noted through routine salmonella surveillance by the colorado department of health. eighteen primary cases with a distinctive antibiotic resistance pattern (tetracycline, streptomycin, and sulfonamides) were evaluated in a case-control study, and illness was found to be associated with eating raw hamburger (p less ...1978623088
interpandemic influenza in the houston area, 1974-76.prospective virologic surveillance has defined two influenza epidemics representing the fifth and sixth outbreaks attributed to h3n2 viruses since the prototype, a/hong kong/68 ((h3n2), emerged in 1968. the 1975 epidemic was caused by influenza a/port chalmers and yielded an estimated attack rate of 9 per cent; the second, attributed to influenza a/victoria, produced an explosive outbreak, with an estimated attack rate of 18 per cent in 1976. the highest morbidity occurred in preschool children, ...1978628375
septicemic melioidosis. occurrence following acute influenza a six years after exposure in vietnam.septicemic melioidosis in association with acute influenza a was diagnosed in a vietnam veteran. the case illustrates that activation of melioidosis can occur long after exposure to a known endemic area and may be precipitated by infections with other common pathogens. hence, physicians must maintain a high index of suspicion of melioidosis when dealing with unexplained sepsis in vietnam veterans. prolonged therapy with appropriate antimicrobial agents is needed to eradicate this infection.1978671709
secular trends in ischemic heart disease and stroke mortality from 1970 to 1976 in spanish-surnamed and other white individuals in bexar county, texas. 1978679445
basal cell nevus syndrome in a black patient: report of a case and review of the literature.an 80-year-old black man had multiple basal cell epitheliomas (bces), palmar pits, and mandibular cysts. this patient is unusual, not only because of multiple bces, but also becuase they developed when the patient was at age 77. only three other black patients with multiple bces in association with basal cell nevus syndrome have been reported previously.1978686749
the russian flu. its history and implications for this year's influenza season.from november 1977 through mid-january 1978 the population younger than 25 years in the union of soviet socialist republics experienced a widespread epidemic of mild influenza (russian flu) caused by an h1n1 virus similar to the virus that circulated worldwide during the early 1950s. outbreaks of russian flu occurred in school populations and military recruits in the united states starting in mid-january. many other countries reported outbreaks of h1n1 virus in the winter of 1978. predictions of ...1978702749
antigenic drift and efficacy of influenza virus vaccines, 1976--1977.a unique opportunity occurred in february 1977 to assess the efficacy of an influenza virus vaccine given to military personnel in doses of 400 chick cell-agglutinating (cca) units of a/victoria/3/75, 400 cca units of a/new jersey/76, and 500 cca units of b/hong kong/72 viruses. after cessation of all influenza virus vaccine administration in mid-december 1976, approximately 200 unvaccinated u.s. air force personnel arrived per week beginning february 1, 1977, at lowry air force base, denver, co ...1978712117
community-wide surveillance of influenza after outbreaks due to h3n2 (a/victoria/75 and a/texas/77) and h1n1 (a/ussr/77) influenza viruses, mercer county, new jersey, 1978. 1978712125
a search for 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) in an environment exposed annually to 2,4,5-trichlorophenoxyacetic acid ester (2,4,5-t) herbicides.as part of a broad study to determine whether 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) is accumulating in the environment due to approved uses of 2,4,5-trichlorophenoxyacetic acid (2,4,5-t) based herbicides, samples of fish, water, mud and human milk were collected from areas in arkansas and texas where 2,4,5-t herbicides are used and were analyzed for tcdd. no tcdd was detected by a gc-ms procedure with a detection limit which averaged less than 10 ppt.1977922189
cooperative state-federal turkey ornithosis task force, texas, 1974.ornithosis was suggested by a routine analysis of tissue specimens from texas turkey flocks submitted to the texas a&m university poultry disease laboratory at gonzales on april 30, 1974, and of subsequent specimens from four additional flocks. subsequently, illness in humans at turkey processing plants in texas, nebraska, and missouri, implicating turkeys from texas, was confirmed as ornithosis in july 1974; and, associated with this outbreak, ornithosis was suspected as the cause of the death ...1976938382
clinical aspects of human venezuelan equine encephalitis in texas.the venezuelan equine encephalitis epidemic which occurred in texas in 1971 produced a wide range of predominantly mild clinical symptoms. this epidemic, which peaked on 13-14 july, was most intensely felt in the far-south counties of cameron and hidalgo. in all, 88 laboratory-confirmed human cases were reported to the u.s. center for disease control by the texas state department of health. the ratio of male to female cases was about two to one. an attack of 20.8 cases per 100,000, observed in b ...1976949558
virological and serological studies of venezuelan equine encephalomyelitis in humans.during the 1971 epidemic of venezuelan equine encephalomyelitis (vee) in south texas, 203 suspect vee cases were evaluated by the center for disease control. sixty-seven were confirmed as cases of vee. laboratory confirmation was accomplished by isolation of vee virus from a serum specimen taken during the acute illness in 50 (75%) of the confirmed cases. serological confirmation was obtained in 17 cases (25%). virus isolations were most often obtained from sera collected during the first 3 days ...1976956360
perspectives on accountability in mental health and retardation services.public mental health and mental retardation agencies are under increasing pressure to demonstrate their accountability in fiscal, legal, program, and other areas. the author discusses some of the problems and issures in pinpointing accountability and identifies eight areas of accountability--to patients, to program and management staff, to a chief executive, to a legislative body, to the public, to one's profession, and to one's self. he describes ways in which accountability can be demonstrated ...1976971906
for where there is love of man, there is also love of the art. 19761006558
autochthonous dermal leishmaniasis in texas.over a 2-year period two cases of dermal leishmaniasis of special interest were recognized in texas. the first occurred in 1972 in a 74-year-old woman who had residences in dilworth and gahzales, gonzales county, and the other was in a 56-year-old man from kenedy, karnes county, in 1974. both cases were biopsy- and culture-positive, and the second patient exhibited anti-leishmania antibodies by indirect immunofluorescent antibody and direct agglutination tests. epidemiologic investigation reveal ...19761034442
the risk of birth defects: jacobs v. theimer and parents' right to know.this article discusses the texas supreme court's holding in jacobs v. theimer that the parents of a defective child had a cause of action for damages against a physician for alleged negligent failure to inform the mother during pregnancy that she had contracted rubella and therefore might have a defective child, thereby causing her to lose the opportunity to have an abortion. the article raises a number of questions that post-jacobs courts probably will confront concerning the duty of physicians ...19761052109
a review of the evidence in retrospect for a rickettsial etiology in bullis fever.the authors have presented evidence through work done 25-30 years ago for the rickettsial etiology of bullis fever, a forgotten epidemic which occurred with over a 1,000 cases among world war ii troops in training at camp bullis, texas. rickettsiae were recovered from blood and lymph nodes of patients and from ticks, amblyomma americanum, collected in the area. all patients gave a history of tick-bites. the human and tick strains of rickettsiae, carried in chick embryo culture and in animal pass ...19751103350
epidemic venezuelan equine encephalitis in north america in 1971: vertebrate field studies.epidemic venezuelan equine encephalitis in north america in 1971: vertebrate field studies. am j epidemiol 101:36-50, 1975.-in june 1971, epidemic venezuelan equine encephalitis (vee) invaded the lower rio grande valley in south texas. the boca chica area of cameron county was selected as a study site to investigate vertebrate involvement in the natural cycle of epidemic vee on the basis of considerable evidence of vee virus activity there in equines, humans, and mosquito vectors. only one vee v ...19751119481
the epidemiology of st. louis encephalitis in dallas, texas, 1966.an epidemic of st. louis encephalitis (sle) occurred in dallas, texas, in the summer of 1966. a total of 545 suspected cases within dallas city and county were reported, of which 145 were laboratory-confirmed as sle virus infection. the greatest concentration of cases occurred in lower socioeconomic areas of the central part of the city in black populations. the attack rate and mortality rate increased markedly with age. the overall attack rate was 15.2 per 100,000, with a case fatality rate of ...19751155433
human psittacosis associated with commercial processing of turkeys.between may 1 and aug 1, 1974, 114 of approximately 1,000 employees in 7 turkey processing plants in texas (5), missouri (1), and nebraska (1) had an illness compatible with psittacosis. the illness was characterized by fever, severe headache, and pneumonia. treatment with tetracycline was effective in most cases. psittacosis was confirmed in 41 (36%) of the cases by a fourfold change in complement-fixation titer to the chlamydia group antigen. investigations implicated several turkey flocks fro ...19751184442
epizootic of anthrax in falls county, texas.an epizootic of anthrax in eastern falls county, texas, killed at least 238 animals during a 6-week period ending july 31, 1974. infection appeared to be caused by the ingestion of contaminated soil and grass in the drought-stricken central texas area. the participation of the texas department of agriculture, the texas national guard, and other state agencies was of great assistance to the texas animal health commission in handling the epizootic and panic stricken public. use of the unencapsulat ...19751184447
canine rabies in the united states, 1971-1973: study of reported cases with reference to vaccination history.from 1971 through 1973 629 reported cases of rabies in dogs, concentrated in the appalachian area, upper mississippi drainage, texas, and louisiana, were reported in the us. states bordering the atlantic and pacific oceans had fewer cases. there was a recurring seasonal pattern of cases with a peak in march and april and a low point in august and september. most of the cases involved transmission from wildlife vectors rather than dog-to-dog transmission. most of the dogs were owned (87%), unvacc ...19761251838
outbreaks of human enteric adenovirus types 40 and 41 in houston day care centers.human enteric adenovirus (ead) types 40 and 41 cause diarrhea in young children, but little is known about their association with outbreaks of diarrhea in the child care setting. this study evaluated ead as a cause of outbreaks of diarrhea among infants and toddlers in day care centers.19921313095
arboviral disease--united states, 1991.during 1991, state and local health departments reported 122 cases of human arboviral encephalitis to cdc. more than half (69) of the cases resulted from outbreaks of st. louis encephalitis (sle) in arkansas and texas. in addition, an epizootic of eastern equine encephalitis (eee) extending from the atlantic and gulf coasts into the upper midwest caused sporadic human cases and a substantial loss of livestock. this report summarizes the reported cases of arboviral encephalitis in the united stat ...19921321947
serological evidence for congenital transmission of human herpesvirus 6. 19921351995
assignment of a locus for familial melanoma, mlm, to chromosome 9p13-p22.linkage analysis of ten utah kindreds and one texas kindred with multiple cases of cutaneous malignant melanoma (cmm) provided evidence that a locus for familial melanoma susceptibility is in the chromosomal region 9p13-p22. the genetic markers analyzed reside in a candidate region on chromosome 9p21, previously implicated by the presence of homozygous deletions in melanoma tumors and by the presence of a germline deletion in an individual with eight independent melanomas. multipoint linkage ana ...19921439824
men's disclosure of hiv test results to male primary sex partners.we evaluated disclosure of human immunodeficiency virus (hiv) antibody status to a main sex partner and the impact on the relationship in men who have sex with men and who are enrolled in the acquired immunodeficiency syndrome (aids) community demonstration projects cohorts. eighty-nine percent of both seronegative and seropositive men disclosed the results to their main sex partner. seventy percent of the seronegative men and 82% of the seropositive men who did so reported that the relationship ...19921456347
prevalence of human immunodeficiency virus infection in hospitalized adults at a teaching hospital in west texas.the prevalence of infection with human immunodeficiency virus (hiv) among hospitalized adults at a teaching hospital in west texas was estimated by conducting a serological survey. of the 2,458 patients tested, 12 (0.5%) were seropositive. all 12 were men of ages 28 through 50 years; 11 were white and 1 was hispanic. eleven were previously known to be hiv positive and were hospitalized for illnesses related to acquired immunodeficiency syndrome (aids). all seropositive patients were hospitalized ...19921462260
risk factors for infection with human immunodeficiency virus among low-income women undergoing voluntary sterilization.data regarding risk for infection with human immunodeficiency virus (hiv) were collected from 486 women who presented in 1989 for tubal sterilization through a clinic operated by a medical school. this clinic was participating in a blind surveillance project administered by the local health department. the project was designed to estimate the prevalence of seropositivity for hiv among women seeking family planning services within the department's catchment area. the expectation was that the popu ...19921462262
rabies surveillance in the united states during 1991.in 1991, 49 states, the district of columbia, and puerto rico reported 6,972 cases of rabies in nonhuman animals and 3 cases in human beings to the centers for disease control. ninety-one percent (6,354 cases) were wild animals, whereas 8.9% (618 cases) were domestic species. the total number of reported cases of rabies increased 42.9% over that of 1990 (4,881 cases), with most of the increase resulting from continued spread of the epizootic of rabies in raccoons in the mid-atlantic and northeas ...19921483899
attitudes, norms, and self-efficacy: a model of adolescents' hiv-related sexual risk behavior.using data from a cross-sectional, statewide survey of 1,720 texas ninth graders in 13 school districts, a model of psychosocial predictors of human immunodeficiency virus (hiv)-related sexual risk behavior was tested. predictor variables in the model, based on variables from the theory of reasoned action and social learning theory, were attitudes, norms, self-efficacy, and behavioral intentions. attitudes, norms, and self-efficacy predicted 36.4% of the variance in the intention to limit the nu ...19921618632
ethical considerations in clinical research. 19921624334
the prevalence of seropositivity for human immunodeficiency virus in patients who have severe trauma.patients who have severe trauma have been reported to have a substantially increased rate of seropositivity for human immunodeficiency virus when compared with the general population. we reviewed the records of 1226 consecutive code-3 trauma patients who were treated at our institution in san antonio, texas, between 1987 and 1989. all of the patients had serum drawn to be tested for the human immunodeficiency virus. in contrast with previously published studies, only 0.8 per cent of these trauma ...19921624480
facultative myiasis by megaselia sp. (diptera: phoridae) in texas: a case report.facultative myiasis caused by larval megaselia sp. is reported in a human in texas. on two occasions during 24 h, the youth experienced a "crawling sensation deep in [his] throat" which caused him to cough, expelling a living megaselia sp. larva. the site of the infestation was presumed to be the sinuses or upper respiratory tract. the symptoms resolved upon expulsion of the larvae, and no additional complications were observed in the patient.19921625307
ocular-systemic interrelationships in acquired immunodeficiency syndrome.we analysed the correlation between ophthalmic and systemic findings in 125 subjects with aids and 50 subjects with aids-related complex (arc). positive eye findings were defined as the presence of cotton-wool spots (cws) or cytomegalovirus (cmv) retinitis. the presence of positive eye findings was significantly more frequent in aids than in arc (p = 0.0001). both lowest haematocrit and lowest t-helper cell count were significantly lower in aids than in arc, and also lower in subjects with posit ...19911645204
incentives for organ donation? the united network for organ sharing ad hoc donations committee. 19911683431
organochlorine compounds in human adipose tissue from north texas.this paper reports a preliminary study that was conducted to determine the concentrations of organochlorine compounds in the adipose tissue of residents of north texas. thirty-five human adipose tissue samples were obtained during autopsy between 1987 and 1988 from persons who had no known occupational exposure to organochlorine pesticides. these samples were analyzed by electron-capture gas chromatographic methods for the presence of beta-benzene hexachloride, o,p'-dde, p,p'-dde, o,p'-ddt, p,p' ...19901688952
intensive chemotherapy for metastatic nonseminomatous germ cell tumors. 19901696741
lithium in drinking water and the incidences of crimes, suicides, and arrests related to drug addictions.using data for 27 texas counties from 1978-1987, it is shown that the incidence rates of suicide, homicide, and rape are significantly higher in counties whose drinking water supplies contain little or no lithium than in counties with water lithium levels ranging from 70-170 micrograms/l; the differences remain statistically significant (p less than 0.01) after corrections for population density. the corresponding associations with the incidence rates of robbery, burglary, and theft were statist ...19901699579
quality of life in persons with human immunodeficiency virus infection: measurement by the medical outcomes study instrument.to assess the reliability and validity of the medical outcomes study (mos) short form health survey as an indicator for quality of life in patients infected with the human immunodeficiency virus (hiv).19921727616
achieving compliance with influenza immunization of medical house staff and students. a randomized controlled trial.to determine the optimal method to increase influenza immunization rates of medical house staff and students.19921740861
lung cancer and hydrogen chloride exposure: results from a nested case-control study of chemical workers.there are few epidemiologic data available to address the question of potential carcinogenic effects of hydrogen chloride (hcl) exposure on humans. an opportunity arose to augment a nominal hcl exposure classification that had been done earlier for a nested case-control study of lung cancer among a cohort of chemical manufacturing employees. working from first-hand knowledge of the relevant chemical processes and limited hcl monitoring data, a certified industrial hygienist estimated average exp ...19911744744
the neuropathology of human immunodeficiency virus infection. the dallas, texas, experience.postmortem neuropathologic changes were evaluated in 141 consecutive patients dying with human immunodeficiency virus infection at publicly supported hospitals affiliated with the university of texas southwestern medical center in dallas, between august 1984 and september 1990. morphologic abnormalities were identified in 112 cases (79%). cytomegalovirus was the most common opportunistic infection encountered, with characteristic viral inclusions identified in 23 patients, and presumptive eviden ...19911747029
characterization of a leishmania isolate from the rodent host neotoma micropus collected in texas and comparison with human isolates.we report the biological and biochemical parameters of leishmania parasites (mneo/us/90/wr972) isolated from a rodent host, neotoma micropus, collected in texas. footpad inoculations of wr972 promastigotes into balb/c mice and syrian hamsters resulted in ulcerating lesions six and eight weeks post-inoculation, respectively. using monoclonal antibody-stained touch preparations, amastigotes were found in the liver of both laboratory hosts. infection of j774 macrophages with wr972 promastigotes sup ...19911763798
results of a prenatal screening program for the human immunodeficiency virus in a cross-sectional population.a prenatal screening program for antibody to the human immunodeficiency virus (hiv) was examined prospectively in a cross-sectional population. routine screening was performed on 3,241 women during the first trimester. serum samples yielding repeatedly positive results on an enzyme-linked immunosorbent assay (elisa) (n = 6) were subjected to confirmatory western blot testing. all the specimens were determined to be false positive with atypical banding regions not consistent with hiv-1 infection. ...19911765954
milk secretory iga related to shigella virulence antigens.20 mexico city and 23 houston, texas colostrum samples, and 21 mexican and 25 houston mature milk samples were analyzed by elisa and western blot, respectively, for antibodies against the virulence plasmid of shigella flexneri serotype 5 strain m9ot. the method involved comparing water extracts of milk in elisa and western blot determinations of antigens against shigella flexneri strain m9ot which is fully virulent, to those against m9ot a2 which lacks the virulence plasmid. while there are at ...19911809012
from the centers for disease control. human rabies--texas, arkansas, georgia, 1991. 19911820460
nosocomial influenza in a general hospital for indigent patients.surveillance of influenza virus infections was maintained on the medical and pediatric wards of a general hospital serving indigent patients of harris county, texas during the winter of 1987-88. influenza a/sichuan/2/87(h3n2) was the predominant virus during the community epidemic. influenza a(h3n2) virus was isolated from six of 17 adult patients (35%) suspected to have nosocomial infections; two of these patients died of fulminating pneumonia. another patient, admitted with alcoholism and hema ...19911824284
from the centers for disease control. human rabies--texas, 1990. 19911847978
sexual abuse of children.sexual abuse of children is a pervasive and growing problem, which has demanded the attention of several professional groups. because most children never reveal the abuse, understanding the psychodynamics involved is fundamental to the detection of these victims. physicians should be aware of the masked clinical and behavioral indicators of sexually abused children that signal the need for further questioning. through appropriate inspection of genitalia and anus in routine examination of the chi ...19911877030
comprehensive care for patients with hemophilia: an expanded role in reducing risk for human immunodeficiency virus.hemophilia is an inherited coagulation disease that affects approximately 1 in 5,000 to 10,000 males worldwide. chronic joint disease and other long-term complications of recurrent bleeding persist in patients with hemophilia despite improved and more available clotting protein concentrates. the best care can be provided to patients who are followed regularly in specialized treatment centers. services of every "comprehensive" hemophilia treatment center (htc) have expanded since previous treatme ...19911877032
update: self-induced malaria associated with malariotherapy for lyme disease--texas.in december 1990, the texas department of health (tdh) was contacted by a man who had recently moved from the northeastern united states and who was considering malariotherapy for lyme disease (ld). he described a 2-year history of unsuccessful treatment with multiple antibiotics for arthralgias and palpitations, which had been diagnosed as ld.19911896006
pilot study of a household survey to determine hiv seroprevalence.a survey based on a probability sample of u.s. households was suggested as a method to determine the number of persons infected with human immunodeficiency virus (hiv). to test the feasibility of such a survey, cdc's national center for health statistics (nchs) recently conducted a pilot study in two sites through a contract with the research triangle institute. the first field test, conducted in january 1989, used a random sample of adults from households in allegheny county (pittsburgh), penns ...19911898620
human rabies--texas, 1990.on june 5, 1990, a 22-year-old man died of rabies encephalitis in hidalgo county, texas, along the mexican border. this was the fourth case of human rabies known to be acquired in the united states since 1980 and the first case in texas since 1985. this report summarizes the case investigation.19911900099
ambient air arsenic levels along the texas-mexico border.the texas-mexico border region is one of the most rapidly developing areas in the state. unprecedented economic and demographic growth is placing stress on a system already overburdened with air, water, waste, and public health problems. this paper reports the results of an initial survey of the past and present ambient air levels of arsenic along the texas side of the border. ambient air arsenic levels have increased over time, exhibit seasonal variations, and are higher in specific areas when ...19911910749
concerns about hospital-based routine human immunodeficiency testing programs. 19911918884
dr. refuses to treat pt. in active labor. case in point: burditt v. u. s. dept. of health & human serv. (932 f. 2d 1362--tx (1991)). 19911924823
cutaneous larva migrans due to pelodera strongyloides.a twenty-year-old landscape worker was evaluated for a widespread cutaneous eruption consisting of papules, pustules, and burrows. cutaneous scrapings revealed live and dead larvae of a free-living soil nematode, pelodera strongyloides. this is the third instance of human dermatitis due to this organism, and the first reported in an adult host.19911935236
familial patterns of prostate cancer: a case-control analysis.epidemiological data have not yet enabled physicians to look beyond age and race to identify men at increased risk for prostate cancer. we conducted a hospital-based case-control study of familial patterns of prostate cancer with self-reported data from a risk-factor questionnaire. there were 385 patients with histologically confirmed prostate cancer, and 385 race and age-matched (+/- 5 years) controls with other cancers. family history, available for 378 patients and 383 controls, was positive ...19911942282
human rabies--texas, arkansas, and georgia, 1991.from august through october 1991, three persons, one each in texas, arkansas, and georgia, died from rabies. including these three cases, 16 cases of human rabies have been reported to cdc from 1980 through 1991; seven of these are believed to have been acquired in the united states. this report summarizes epidemiologic and clinical information regarding the three recent cases.19911944123
update: influenza activity--united states, 1991-92.from late october through november 20, 1991, state health departments reported outbreaks of culture-confirmed influenza a(h3n2) in public schools in texas and a university in tennessee. in addition, alabama, georgia, minnesota, north carolina, ohio, and tennessee reported outbreaks of culture-confirmed influenza a (not subtyped) in schools. in these outbreaks, school absentee rates ranged from 11% to 40%; school closures were reported in ohio and tennessee.19911944132
surveillance for hiv antibody and antigen in trauma patients.studies in a baltimore emergency room identified the patient with penetrating trauma as having the highest incidence of human immunodeficiency virus type i (hiv-1) infection. anonymous testing over a 15-month period of 165 victims of penetrating trauma presenting to the medical center hospital emergency center (san antonio, texas) revealed a 0% incidence of hiv-1. this data suggests that hiv-1 trauma patient incidence can be expected to vary between specific geographic areas and patient populati ...19911955674
update: influenza activity and vaccine availability--united states, 1991-92.during the 1991-92 influenza season, widespread influenza-like illness (ili) activity* was first reported in louisiana for the week ending november 9, 1991, and in mississippi the week ending november 16. through november 30, six additional states (alaska, missouri, new york, north carolina, tennessee, and texas) reported widespread activity; 13 (alabama, arkansas, california, florida, georgia, indiana, kansas, kentucky, minnesota, nebraska, new jersey, ohio, and pennsylvania) reported regional ...19911961177
health, human services reorganization falls short of real consolidation. 19911962298
age distribution of patients with medically-attended illnesses caused by sequential variants of influenza a/h1n1: comparison to age-specific infection rates, 1978-1989.since influenza a/h1n1 viruses reappeared during the 1977-1978 season, this subtype has contributed 27% of 6,609 documented influenza infections of persons with acute respiratory disease presenting to clinics serving as surveillance sites of the influenza research center in houston for the 12-year period ending june 1989. wide differences in the distribution of h1n1 viruses occurred by age group: more than 50% of h1n1 infections were detected among persons aged 10-34 years, compared with 28% for ...19912000847
acquired immunodeficiency syndrome and adolescents. knowledge, attitudes, and behaviors of runaway and homeless youths.to describe the knowledge, attitudes, and behaviors of runaway and homeless youths regarding infection with the human immunodeficiency virus (hiv).19912012028
nih awards genome project grant to baylor college of medicine. 19912031224
hiv prevalence in pregnant intravenous drug users in dallas, texas.information available regarding the prevalence of human immunodeficiency virus (hiv) in pregnant women indicates that the primary risk factor for infection is intravenous drug use. at parkland memorial hospital in dallas, texas, approximately 4.7% of pregnant women reported using intravenous drugs. the estimated prevalence of hiv infection among pregnant intravenous drug users at this hospital was 3.3%. this is similar to the hiv infection rates reported for nonpregnant parenteral drug-using pop ...19912035151
the burditt case: 1,000 briefs, but who's counting? 19912035153
epidemiologic characteristics of human tularemia in the southwest-central states, 1981-1987.from 1981 through 1987, a total of 1,041 cases of tularemia in humans were reported in arkansas, kansas, louisiana, missouri, oklahoma, and texas; this represents 60% of the cases reported in the united states during this same time period. the state of arkansas reported the highest total (420 cases). annual incidence rates per one million population ranged from 36.3 in arkansas to less than 5.0 in kansas, louisiana, and texas. epidemiologic data were available for 1,026 cases. the majority of ca ...19912035503
htlv-i-associated myelopathy endemic in texas-born residents and isolation of virus from csf cells.we report three texas-born patients with spastic paraparesis and well-documented infection with htlv-i. csf examination showed moderate pleocytosis, protein elevation, and elevated igg index. oligoclonal bands were present in two patients. on mri, one patient had frontal lobe lesions that were low intensity on t1- and high intensity on t2-weighted images. htlv-i immunoblot studies of serum and csf revealed reactivity to p19, p24, p53, gp46, or gp68 from all three patients. titration studies of s ...19912046926
epidemiology of acquired immunodeficiency syndrome and human immunodeficiency virus infection in adolescents.the epidemiology of acquired immunodeficiency syndrome (aids) and human immunodeficiency virus infection (hiv) in adolescents is important for purposes of prevention and car, since sexual and drug behavior is formed during this period. for 1990 the centers for disease control reports .4% of aids cases are among adolescents 13-19 years old; this figure has steadily risen since 1982. 53% of the reported aids cases were from new york, florida, california, texas, puerto rico, and new jersey, and has ...19912062630
serologic survey of selected zoonotic disease agents in black-tailed jack rabbits from western texas.a serologic survey for the agents of rocky mountain spotted fever (rmsf) (rickettsia rickettsii), borrelia spp. including the causative agent for lyme disease (borrelia burgdorferi), and plague (yersinia pestis) was conducted on blood samples collected from 30 and 46 black-tailed jack rabbits (lepus californicus) from an urban environment in lubbock, texas (usa) during winter 1987 and the following spring 1988, respectively. antibody titers to the agents of rmsf and borreliosis were detected in ...19902106044
evaluation of a hospital admission hiv antibody voluntary screening program.voluntary screening for the presence of human immunodeficiency virus (hiv) is recommended by the healthcare profession. the optimal settings to accomplish screening have not been established. we evaluated an admission hiv screening program in a large private hospital to assess advantages and disadvantages in this setting. in a three-month study period, 4,535 of 8,868 patients (51%) admitted to the hospital agreed to hiv testing. serum specimens from 500 patients who refused testing were blindly, ...19902125612
varicella outbreaks in army recruits from puerto rico. varicella susceptibility in a population from the tropics.two outbreaks of varicella consisting of a total of 105 cases occurred in a highly varicella-susceptible population of young adult army recruits from puerto rico enrolled in the defense language institute in san antonio, tex, between october 1986 and november 1987. epidemiologic investigation found a significantly higher risk for enlisted recruits housed in open barracks than for officers housed in private rooms. the attack rate in the first outbreak was 30%, with an estimated attack rate of 71% ...19902158774
asymptomatic human calicivirus infection in a day care center.human caliciviruses (hcvs) are little known, recently recognized viruses associated with gastroenteritis. we identified hcv infection in an outbreak of gastroenteritis which occurred in one room of a day care center (dcc) participating in a longitudinal study of diarrhea. utilizing an enzyme-linked immunoassay and immunosorbent electron microscopy to detect hcv, we tested specimens from all children in attendance during the period of the illness outbreak and during prior and subsequent weeks. hc ...19902159612
serotype variation of human group a rotaviruses in two regions of the usa.the first longitudinal study of group a rotavirus serotype distribution in the usa is reported. elisas incorporating neutralizing monoclonal antibodies specific for the vp7 protein of serotypes 1, 2, 3, and 4 were used to determine the antigenic variation of group a rotaviruses in two collections of stool specimens. stool samples were collected from children hospitalized during 1979-1989 at texas children's hospital, houston, and from children from a more rural population hospitalized during 198 ...19902167332
morbidity associated with the major respiratory viruses. 19902172898
circannual variation of human mortality in texas. 19902217299
transfer law puts rural internist between a rock and a hard place. 19902218949
legal issues, aids, and the practicing physician.this article highlights for the practicing physician some of the more important laws and regulations related to and arising from the aids epidemic. medical-legal issues regarding the availability of health care as defined by federal and state law regarding employment and level of medical care given based on hiv status is discussed. texas law regarding testing, disclosure of test results, and possible claims that could arise due to issues such as the invasion of privacy are examined along with cr ...19902218960
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