Publications

hla-b alleles, high-risk hpv infection and risk for cervical neoplasia in southern chinese women.	a population-based study was conducted on 256 southern chinese with cervical intraepithelial neoplasia grade iii (cin iii) or invasive cervical cancer (icc) and on 258 controls to examine the associations between hla-b alleles, infection with high-risk human papillomaviruses (hpvs) and the development of cervical neoplasia. hla-b15 was found to be protective for cin iii/icc overall (p(corrected) = 0.003), and for hpv52-positive cin iii/icc (p(corrected) = 0.003). a marginal protective effect of ...	2006	16206270
profile of viral load, integration, and e2 gene disruption of hpv58 in normal cervix and cervical neoplasia.	the clinical utility of viral-load and integration status of human papillomavirus (hpv) infection remains uncertain. we examined 75 women infected with hpv58, a worldwide rare type found to be prevalent in cervical cancers in eastern asia. viral load was significantly higher for cervical intraepithelial neoplasia (cin) 1/2, but those for a normal control group and for cin 3 or cancer overlapped substantially. a pure integrated genome was found for all lesion grades, giving a poor positive predic ...	2007	17703417
epidemiology of human papillomavirus infection and cervical cancer and future perspectives in hong kong, singapore and taiwan.	hong kong, singapore and taiwan are three island states that are newly emerged affluent economic areas in asia. the majority of the populations are ethnically chinese with a total population of 6.98, 4.5 and 23 million, respectively. cervical cancer has been declining over the last thirty years in all three states and is largely attributable to widespread opportunistic cervical cancer screening. the age-standardized incidence rates of cervical cancer are 9.6 per 100,000 women in hong kong in 200 ...	2008	18945415
distribution of human papillomavirus types in cervical cancers in hong kong: current situation and changes over the last decades.	human papillomavirus (hpv) type distribution among cervical cancers and its possible changes over time are key issues that determine the cost-effectiveness of hpv vaccines. cervical cancers diagnosed during 3 periods (1997-2007, n = 280; 1984-1986, n = 74; 1972-1973, n = 81) in hong kong were examined for hpv type distribution using sensitive broad-catching methods. the results showed a variation in hpv distribution between histological groups. among cervical squamous cell carcinoma (scc) cases ...	2009	19507252
psychological burden of testing positive for high-risk human papillomavirus on women with atypical cervical cytology: a prospective study.	to assess the psychological burden of testing positive for high-risk human papillomavirus (hpv) on chinese women with atypical squamous cells of undetermined significance (ascus).	2011	21306349