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a large outbreak of acute gastroenteritis associated with astrovirus among students and teachers in osaka, japan.in june 1991, a large outbreak of acute nonbacterial gastroenteritis occurred among students and teachers at 10 primary and 4 junior high schools in katano city, osaka, japan. the outbreak affected > 4700 persons, lasted 5 days, and was believed to have been linked to contaminated food from a common supplier. astrovirus, identified as the etiologic agent, was detected by direct electron microscopy in 10 of 38 fecal samples obtained from patients with diarrhea. detection was confirmed by solid-ph ...19948035033
genomic characterization of human astrovirus type 6 katano virus and the establishment of a rapid and effective reverse transcription-polymerase chain reaction to detect all serotypes of human astrovirus.we previously reported that human astrovirus type 6 (hastv t6) was the etiologic agent of a large-scale outbreak of acute gastroenteritis that occurred in 1991 in katano city, osaka, japan [oishi et al., 1994]. the two representative strains, katano virus k23 and k24, have been analyzed by sequencing the open reading frame 2 (orf2) region after amplification by reverse transcription-polymerase chain reaction (rt-pcr). the orf2 region of hastv t6 strains, including k23, was found to be about 20 b ...200010745244
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