Publications

prevalence of antibody to legionella pneumophila in middle-aged and elderly americans.	an indirect fluorescent antibody (ifa) test was used to establish the background prevalence of antibody to legionella pneumophila in single serum specimens from 1,143 persons. the serum specimens had been obtained from volunteers 46 years of age and older who were not acutely ill and who resided in the areas of atlanta, georgia; washington, d.c.; houston, texas; and rochester, new york. the overall prevalence of seropositivity (reciprocal titer, greater than or equal to 64) was 1.7%. the prevale ...	1979	393779
pontiac fever outbreak associated with a cooling tower.	in late april 1984, an outbreak of pontiac fever was investigated in an office building in lower manhattan (new york city). the outbreak was characterized by a high attack rate (78 per cent overall); the predominant symptoms were myalgias, chills, fatigue, fever, and headache. there was a clustering of cases in an office that was air cooled by a dedicated cooling tower separate from the remainder of the building. a high concentration of live l. pneumophila cells in the cooling tower was quantifi ...	1987	3565648
a community hospital outbreak of legionellosis. transmission by potable hot water.	seven cases of nosocomial legionellosis occurred between february and september 1982 in a small community hospital in upstate new york. all seven were cases of legionella pneumophila serogroup 1; six were hospital patients and one a hospital employee. none of the cases died. during the peak of the outbreak, the incidence of nosocomial legionellosis was 1.2 cases per 100 patient discharges. an epidemiologic comparison of the six patient cases with 21 matched patient controls suggested that longer ...	1987	3826043
seroepidemiology of legionella pneumophila serogroup 1 in healthy residents of new york city.		1985	3856118
are air-conditioning maintenance personnel at increased risk of legionellosis?	we surveyed by use of medical questionnaires and blood tests 21 maintenance workers involved with cleaning and servicing cooling towers and evaporative condensers at a large company to determine the frequency of pneumonia and antibody levels against legionella pneumophila serogroup 1. the 21 high-risk workers were compared with 27 low-risk workers, persons who were not directly involved in service or maintenance for the company. the overall prevalence of titers greater than or equal to 128 for t ...	1980	7406491
typing of legionella pneumophila serogroup 1 isolates by degenerate (d-)rapd fingerprinting.	a new method to identify clonal strains of pathogenic bacteria has been developed recently in this laboratory. the method utilizes degenerate random amplified polymorphic dna primers (d-rapd) to amplify random fragments in crude bacterial lysates, generating reproducible dna banding profiles or fingerprints. we use this method to type outbreak and non-outbreak isolates of legionella pneumophila serogroup 1 from four hospitals near to, and affiliated with the university of pittsburgh medical cent ...	1995	8808311
nosocomial legionellosis traced to a contaminated ice machine.	to investigate a case of nosocomial legionellosis, identify pathways of transmission, and effect control of the environmental source.	1997	9309436
an outbreak of legionella micdadei pneumonia in transplant patients: evaluation, molecular epidemiology, and control.	to describe a nosocomial outbreak of legionella micdadei pneumonia in transplant patients and to characterize the source of the outbreak and the control measures utilized.	2000	11014721
unexplained increased incidence of legionnaires disease during the "herald wave" of the h1n1 influenza pandemic.		2010	20367323
active bacterial core surveillance for legionellosis - united states, 2011-2013.	during 2000–2011, passive surveillance for legionellosis in the united states demonstrated a 249% increase in crude incidence, although little was known about the clinical course and method of diagnosis. in 2011, a system of active, population-based surveillance for legionellosis was instituted through cdc’s active bacterial core surveillance (abcs) program. overall disease rates were similar in both the passive and active systems, but more complete demographic information and additional clinica ...	2015	26513329
genomic resolution of outbreak-associated legionella pneumophila serogroup 1 isolates from new york state.	a total of 30 legionella pneumophila serogroup 1 isolates representing 10 separate legionellosis laboratory investigations ("outbreaks") that occurred in new york state between 2004 and 2012 were selected for evaluation of whole-genome sequencing (wgs) approaches for molecular subtyping of this organism. clinical and environmental isolates were available for each outbreak and were initially examined by pulsed-field gel electrophoresis (pfge). sequence-based typing alleles were extracted from wgs ...	2016	27060122