Publications

antibacterial properties of investigational, new, and commonly used antibiotics against isolates of pseudomonas cepacia in michigan.	microdilution antimicrobial susceptibility testing was performed with 73 isolates of pseudomonas cepacia collected from the sputum of patients throughout michigan with cystic fibrosis. susceptibility testing was done using new and investigational antibiotics (loracarbef, cefixime, cefpirome, desacetyl-cefotaxime, cefpodoxime, cefmetazole, cefepime, cefprozil, and fleroxacin) and commonly used antibiotics (ceftazidime, mezlocillin, piperacillin, ciprofloxacin, tobramycin, and amikacin). ceftazidi ...	1992	1283733
pseudomonas cepacia at summer camps for persons with cystic fibrosis.	pseudomonas cepacia (pc) is a multidrug-resistant, gram-negative bacillus that causes chronic colonization and infection of the respiratory tract of persons with cystic fibrosis (cf). pc colonization is usually difficult to eradicate with antimicrobial therapy and, in some patients, infection is associated with rapid decline in pulmonary function, increased hospitalization, and earlier death. previous studies have suggested person-to-person transmission of pc both within and outside of hospitals ...	1993	7684813
analysis of competition in soil among 2,4-dichlorophenoxyacetic acid-degrading bacteria.	competition among indigenous and inoculated 2,4-dichlorophenoxyacetic acid (2,4-d)-degrading bacteria was studied in a native kansas prairie soil following 2,4-d additions. the soil was inoculated with four different 2,4-d-degrading strains at densities of 10(3) cells per g of soil; the organisms used were pseudomonas cepacia dbo1(pjp4) and three michigan soil isolates, strain 745, sphingomonas paucimobilis 1443, and pseudomonas pickettii 712. following 2,4-d additions, total soil dna was extrac ...	1994	8017909
genetic relatedness of burkholderia (pseudomonas) cepacia isolates from five cystic fibrosis centers in michigan.	burkholderia cepacia isolates from patients with cystic fibrosis (cf) attending five cf centers were studied for relatedness by cellular fatty acid methyl esters (fame) and by chromosomal dna restriction analysis. twenty-eight of 32 (87.5%) isolates tested were grouped in cluster group 1 based on their fame profiles. dna analysis revealed that 29 of 32 (90.6%) b. cepacia isolates from five cf centers had one closely related dna pattern. to examine strain variation over a time period, fame profil ...	1997	9338052
identification and onion pathogenicity of burkholderia cepacia complex isolates from the onion rhizosphere and onion field soil.	burkholderia cepacia complex strains are genetically related but phenotypically diverse organisms that are important opportunistic pathogens in patients with cystic fibrosis (cf,) as well as pathogens of onion and banana, colonizers of the rhizospheres of many plant species, and common inhabitants of bulk soil. genotypic identification and pathogenicity characterization were performed on b. cepacia complex isolates from the rhizosphere of onion and organic soils in michigan. a total of 3,798 put ...	2008	18344334
genetic diversity and multihost pathogenicity of clinical and environmental strains of burkholderia cenocepacia.	a collection of 54 clinical and agricultural isolates of burkholderia cenocepacia was analyzed for genetic relatedness by using multilocus sequence typing (mlst), pathogenicity by using onion and nematode infection models, antifungal activity, and the distribution of three marker genes associated with virulence. the majority of clinical isolates were obtained from cystic fibrosis (cf) patients in michigan, and the agricultural isolates were predominantly from michigan onion fields. mlst analysis ...	2009	19542323