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population-based analysis of actinobacillus pleuropneumoniae apxiva for use as a diva antigen.apxiva is an rtx toxin of actinobacillus pleuropneumoniae that is a candidate antigen to differentiate infected from vaccinated animals (diva). insertion of isapl1 into the apxiva gene is known to compromise an apxiva-based diva approach, as is potentially a tgg to tga mutation in the apxiva gene. isapl1 was found in 63/349 (18.1%) a. pleuropneumoniae isolates from england and wales including serovars 2, 3, 6-8 and 12. no isapl1 insertions into apxiva were found. only two serovar 3 isolates cont ...201020483193
prevalence of actinobacillus pleuropneumoniae serovars in england and wales. 201021257468
actinobacillus pleuropneumoniae serovar 8 predominates in england and wales. 201627531715
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