Publications

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mapping and comparison of the b-cell epitopes recognized on the plasmodium vivax circumsporozoite protein by immune colombians and immunized aotus monkeys.plasma samples of individuals from two malaria-endemic villages on the colombian pacific coast and synthetic peptides representing different fragments of the central and flanking regions of the plasmodium vivax circumsporozoite protein (csp) were used to perform a fine mapping of the b-cell epitopes on the whole csp. in addition, the immunogenicity of long polypeptides corresponding to the amino (n) and carboxyl (c) regions was evaluated in aotus monkeys. the epitopes recognized after natural in ...19989797827
assessment of therapeutic response of plasmodium vivax and plasmodium falciparum to chloroquine in a malaria transmission free area in colombia.in order to determine the frequency of therapeutic failures to chloroquine (cq) in patients with malaria due to either plasmodium falciparum or p. vivax, and to explore the usefulness of a malaria-free city as a sentinel site to monitor the emergence of drug resistance, 53 patients (44 infected with p. vivax and 9 with p. falciparum) were evaluated at the laboratory of parasitology, universidad del valle in cali, colombia. patients received 25 mg/kg of cq divided in three doses over 48 h; they w ...200212118291
[concordance between thick blood smear, immunochromatography and polymerase chain reaction for malaria diagnosis].the rapid and effective diagnosis of malaria is the determining condition for an appropriate treatment and control of the disease.200818719728
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