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[assessment of the efficacy of antimalarial drugs in tarapacá, in the colombian amazon basin].the current antimalarial drug policy in colombia has been based on studies conducted in antioquia and the pacific coast. however, the efficacy of antimalarial drugs in other endemic regions is unknown.200717546230
deletion of plasmodium falciparum histidine-rich protein 2 (pfhrp2) and histidine-rich protein 3 (pfhrp3) genes in colombian parasites.a number of studies have analyzed the performance of malaria rapid diagnostic tests (rdts) in colombia with discrepancies in performance being attributed to a combination of factors such as parasite levels, interpretation of rdt results and/or the handling and storage of rdt kits. however, some of the inconsistencies observed with results from plasmodium falciparum histidine-rich protein 2 (pfhrp2)-based rdts could also be explained by the deletion of the gene that encodes the protein, pfhrp2, a ...201526151448
genetic characterisation of plasmodium falciparum isolates with deletion of the pfhrp2 and/or pfhrp3 genes in colombia: the amazon region, a challenge for malaria diagnosis and control.most plasmodium falciparum-detecting rapid diagnostic tests (rdts) target histidine-rich protein 2 (pfhrp2). however, p. falciparum isolates with deletion of the pfhrp2 gene and its homolog gene, pfhrp3, have been detected. we carried out an extensive investigation on 365 p. falciparum dried blood samples collected from seven p. falciparum endemic sites in colombia between 2003 and 2012 to genetically characterise and geographically map pfhrp2- and/or pfhrp3-negative p. falciparum parasites in t ...201627636709
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