Publications

relationship between anaemia, iron and folacin deficiency, haemoglobinopathies and parasitic infection.	iron status, folacin status, haemoglobinopathies, malarial infection and intestinal parasitosis frequencies were assessed in a representative sample of 586 subjects living in a rural district of south benin. anaemia according to who reference values for haemoglobin was observed in 42 per cent of subjects. the prevalence was higher in children and menstruating women. iron deficiency, defined by two or more abnormal values in the four independent indicators of iron status used (transferrin saturat ...	1986	3533863
no influence of the transmission season on genetic diversity and complexity of infections in plasmodium falciparum isolates from benin.	the principal goals of the present study were to determine the genetic diversity of the merozoite surface protein-1 (msp-1) and protein-2 (msp-2) genes and the complexity of infections in p. falciparum isolates collected from beninese patients during high and low transmission season at cotonou, in south benin. sixty and twenty-four patients were sampled during dry and wet season respectively. parasite dna was analysed using allele-specific primers to amplify block 2 of msp-1 and central variable ...	2001	14513933
[no influence of season of transmission nor age of patients on the complexity and genetic diversity of plasmodium falciparum infection in cotonou, benin].	the aim of the present study was to determine the genetic diversity and allelic frequencies of the genes encoding for the merozoite surface protein-1 (msp-1) and protein-2 (msp-2) of p. falciparum collected from beninese patients during the high and low transmission seasons in cotonou, in south benin. sixty and twenty-four patients were sampled during the dry and wet seasons, respectively parasite dna was analysed using allele-specific primers to amplify block2 of msp-1 and central variable regi ...	2001	16579077
pfhrp2 and pfldh antigen detection for monitoring the efficacy of artemisinin-based combination therapy (act) in the treatment of uncomplicated falciparum malaria.	an assessment of the accuracy of two malaria rapid diagnostic tests (rdt) for the detection of plasmodium falciparum histidine-rich protein 2 (pfhrp2) or pf lactate dehydrogenase (pfldh) was undertaken in children aged between six and 59 months included in an anti-malarial efficacy study in benin.	2009	19735557
can treatment of malaria be restricted to parasitologically confirmed malaria? a school-based study in benin in children with and without fever.	applying the switch from presumptive treatment of malaria to new policies of anti-malarial prescriptions restricted to parasitologically-confirmed cases is a still unsolved challenge. pragmatic studies can provide data on consequences of such a switch. in order to assess whether restricting anti-malarials to rapid diagnostic test (rdt)-confirmed cases in children of between five and 15 years of age is consistent with an adequate management of fevers, a school-based study was performed in allada, ...	2010	20406492
malaria infection and disease in an area with pyrethroid-resistant vectors in southern benin.	this study aimed to investigate baseline data on malaria before the evaluation of new vector control strategies in an area of pyrethroid-resistance of vectors. the burden of malaria was estimated in terms of infection (prevalence and parasite density) and of clinical episodes.	2010	21194470
genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in plasmodium falciparum isolates from children in south of benin.	the aim of this study was to determine the genetic diversity of plasmodium falciparum by analyzing the polymorphism of the msp-1 and msp-2 genes and the multiplicity of infection in children with uncomplicated malaria in southern benin. blood samples of children with fever or history of fever with thick smear positive p. falciparum were collected on filter paper. after extraction of dna by chelex®, the samples underwent nested pcr. 93 isolates from children were genotyped. for the msp-1 gene, th ...	2013	24135216
incidence of malaria-related fever and morbidity due to plasmodium falciparum among hiv1-infected pregnant women: a prospective cohort study in south benin.	malaria and hiv are two major causes of morbidity and mortality among pregnant women in sub-saharan africa. foetal and neonatal outcomes of this co-infection have been extensively studied. however, little is known about maternal morbidity due to clinical malaria in pregnancy, especially malaria-related fever, in the era of generalized access to antiretroviral therapy and anti-malarial preventive strategies.	2014	24996807
transmission patterns of plasmodium falciparum by anopheles gambiae in benin.	to better control malaria, the clear and urgent need is for improved data to inform decision makers, but in several african countries, there is a lack of baseline data on vectors and variation in the intensity of malaria transmission. this has resulted in the implementation of vector control efforts that ignore variation in vector behaviour and intensity of transmission, an approach that is most often not cost-effective. this study presents a detailed entomological description of mosquito distri ...	2014	25412948
application of polovodova's method for the determination of physiological age and relationship between the level of parity and infectivity of plasmodium falciparum in anopheles gambiae s.s, south-eastern benin.	polovodova method based on counting follicular dilatations estimates the number of egg-laying in mosquitoes. however, some researchers doubt the reliability of this method because of the absence of multiple dilatations in vectors after many gonotrophic cycles. it is in this context of controversy that our study was carried out to evaluate the importance of follicular dilatations in the determination of parity levels in an. gambiae s.s. moreover, the application of this method allowed us to clari ...	2015	25890190