Publications

gram-negative bacteria and b27 disease.	the role of infection in ankylosing spondylitis is speculative and different studies by several groups have yielded conflicting results. the role of infection, however, in reactive arthritis and reiter's syndrome is well established. the grampian region has experienced three outbreaks of gastroenteritis, two due to campylobacter jejuni and one due to salmonella typhimurium. these outbreaks have allowed a study of reactive arthritis in the affected population following these infections. these stu ...	1983	6606475
an outbreak of campylobacter enteritis--a rheumatological followup survey.	one hundred and thirty individuals with bacteriologically proven campylobacter jejuni enteric infection in a single outbreak were studied. eighty-eight patients had gastrointestinal symptoms. one probable example of reactive arthritis was found. this is a frequency similar to that found in other comparable series of salmonella typhimurium and shigella flexneri infections, suggesting a common pathogenesis for the reactive arthritis associated with these 3 infections.	1983	6842468
a milk-borne outbreak of campylobacter infection.	campylobacter jejuni was isolated from the stools of 148 patients with symptoms and 57 symptomless subjects, and from a milk sock filter, following an outbreak of enteritis associated with consumption of unpasteurized milk. the incubation period ranged from 2-11 days with a peak at 5 days. there were no secondary cases. the attack rate was around 50%. cases occurred in all age groups but were maximal in the 1-10 age group. recovery from symptoms was complete in the majority in less than 1 week. ...	1980	7052223
an outbreak of escherichia coli o157 and campylobacteriosis associated with contamination of a drinking water supply.	stream water into which treated sewage discharged contaminated the public water supply of a fife village with a population of about 1100. of 765 residents and workers who reported illness 711 had gastrointestinal symptoms and 633 were defined as cases. mains water analysis revealed high faecal coliform counts. an outbreak of campylobacter and e coli 0157 infection was bacteriologically confirmed in eight and six people respectively. two of the latter developed haemolytic uraemic syndrome. all af ...	1996	8885663
molecular epidemiological investigation of an outbreak of campylobacter jejuni identifies a dominant clonal line within scottish serotype hs55 populations.	three molecular typing methods, pulsed-field gel electrophoresis (pfge), ribotyping, and flagellin (flaa) gene typing, were used to discriminate within a group of 28 campylobacter jejuni, heat-stable serotype 55 (hs55) isolates derived from cases of campylobacter enteritis occurring throughout scotland, including 9 isolates associated with an outbreak. pfge was found to be most discriminatory, identifying 6 distinct profiles, followed by ribotyping (5 profiles), and then flagellin gene typing (4 ...	1999	10459638
campylobacter immunity and coinfection following a large outbreak in a farming community.	an outbreak of campylobacteriosis affected approximately one-half of 165 people attending an annual farmers' dance in montrose, scotland, in november 2005. epidemiological investigations, including a cohort study (n = 164), identified chicken liver paté as the most likely vehicle of infection. paté preparation involved deliberate undercooking of chicken livers by flash-frying, followed by mechanical homogenization. typing of 32 campylobacter strains (isolated from submitted stools) by multilocus ...	2009	19005146
campylobacter genotypes from food animals, environmental sources and clinical disease in scotland 2005/6.	a nationwide multi-locus sequence typing (mlst) survey was implemented to analyze patterns of host association among campylobacter jejuni and campylobacter coli isolates from clinical disease in scotland (july 2005-september 2006), food animals (chickens, cattle, sheep, pigs and turkey), non-food animals (wild birds) and the environment. sequence types (sts) were determined for 5247 clinical isolates and 999 from potential disease sources (augmented with 2420 published sts). certain sts were ove ...	2009	19269051
spatiotemporal homogeneity of campylobacter subtypes from cattle and sheep across northeastern and southwestern scotland.	source attribution using molecular subtypes has implicated cattle and sheep as sources of human campylobacter infection. whether the campylobacter subtypes associated with cattle and sheep vary spatiotemporally remains poorly known, especially at national levels. here we describe spatiotemporal patterns of prevalence, bacterial enumeration, and subtype composition in campylobacter isolates from cattle and sheep feces from northeastern (63 farms, 414 samples) and southwestern (71 farms, 449 sampl ...	2009	19700557
prevalence of campylobacter spp. in raw retail poultry on sale in northern ireland.	a year-long survey of fresh, retail poultry products on sale in northern ireland was undertaken to define the prevalence of campylobacter spp. by using protocols based on iso (standard) 10272-1:2006. incubation at 37 and 42 degrees c was undertaken to increase the diversity of isolates obtained. overall, 652 isolates were identified as campylobacter spp. by using pcr and amplified fragment length polymorphic typing. phenotyping wrongly identified 21% of isolates. prevalences of campylobacter fou ...	2009	19777882
campylobacter excreted into the environment by animal sources: prevalence, concentration shed, and host association.	an intensive study of 443 isolates of campylobacter jejuni and campylobacter coli from 2031 fecal samples excreted by animal sources including cattle, sheep, and pigs, a range of wild and domesticated avian species and pets is described. the prevalence found in the majority of animal sources ranged from 22% to 28% with poultry being highest at 41% and cats and dogs lowest (<5%). the average count excreted for each animal source was found not to be significantly different ranging from approximate ...	2009	19839759
multi-locus sequence types of campylobacter carried by flies and slugs acquired from local ruminant faeces.	to assess whether flies and slugs acquire strains of campylobacter jejuni and campylobacter coli present in local ruminant faeces.	2010	20337762
using sequence data to identify alternative routes and risk of infection: a case-study of campylobacter in scotland.	genetic typing data are a potentially powerful resource for determining how infection is acquired. in this paper mlst typing was used to distinguish the routes and risks of infection of humans with campylobacter jejuni from poultry and ruminant sources	2012	22462563
evidence of land-sea transfer of the zoonotic pathogen campylobacter to a wildlife marine sentinel species.	environmental pollution often accompanies the expansion and urbanization of human populations where sewage and wastewaters commonly have an impact on the marine environments. here, we explored the potential for faecal bacterial pathogens, of anthropic origin, to spread to marine wildlife in coastal areas. the common zoonotic bacterium campylobacter was isolated from grey seals (halichoerus grypus), an important sentinel species for environmental pollution, and compared to isolates from wild bird ...	2015	25401947