Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [in vitro antibacterial activity of new derivatives of pyridonecarboxylic acid, norfloxacin, ofloxacin, enoxacin and ciprofloxacin, against vibrio cholerae o-1]. | 1987 | 3112282 | |
| studies on transmission of human non-a, non-b hepatitis to marmosets. | two sera obtained from four healthy blood donors, which caused non-a, non-b post-transfusion hepatitis in two recipients, were experimentally inoculated into nine marmosets. three of seven marmosets developed acute hepatitis characterized by the elevation of serum concentrations of glutamic pyruvic transaminase (gpt) and/or isocitric dehydrogenase (icd) 8-11 weeks after inoculation. four of seven showed histopathological changes of acute hepatitis in liver biopsy specimens during the biochemical ... | 1987 | 3112304 |
| proteinuria: value as predictor of cardiovascular mortality in insulin dependent diabetes mellitus. | the relation between diabetic microangiopathy and macroangiopathy was studied by analysing the relative mortality from cardiovascular disease in patients with insulin dependent diabetes mellitus with and without persistent proteinuria. the study group comprised 2890 diabetics diagnosed between 1933 and 1972 before the age of 31, and the study was conducted by using the linear logistic discrete failure time model. in patients with proteinuria the relative mortality from cardiovascular disease was ... | 2011 | 3113569 |
| oesophageal pain exacerbated by propranolol. | 2011 | 3113570 | |
| medical stereotypes and medical realities. | 2011 | 3113577 | |
| structural and immunochemical characterization of the o-haptens of brucella abortus lipopolysaccharides from strains 19 and 2308. | the o-haptens of the major fraction (f5a) of b. abortus (strains 2308 and 19) membrane bound smooth lipopolysaccharide (slps) were prepared by hydrolysis of f5a native slps in 1% acetic acid at 100 degrees c for 2 h. after hydrolysis, o-haptens were separated from lipid a-protein complex by centrifugation, and from small fragments by ultrafiltration of molecular weight cut-off (mwco) 1.0 x 10(3). these carbohydrate haptens were identified by precipitin-inhibition assay and further fractionated b ... | 1987 | 3114617 |
| schistosoma mansoni: autoradiographic tracking studies of isotopically-labelled challenge parasites in naive and vaccinated cba/ca mice. | the migration of isotopically-labelled challenge parasites of schistosoma mansoni in naive cba/ca mice, and cba/ca mice vaccinated 4 weeks previously with about 600 radiation-attenuated cercariae, has been followed by means of compressed organ autoradiography. in naive mice, only 16% of the challenge parasites failed to migrate from the skin to the lungs, whereas up to half of the individuals that succeeded in reaching the pulmonary vasculature did not move on to the liver. the tracking techniqu ... | 1987 | 3114702 |
| implication of ornithine decarboxylase and polyamines in pancreatic growth of neonatal rats. | the current study examines the effects of alpha-difluoromethylornithine (dfmo), an irreversible ornithine decarboxylase inhibitor, on pancreatic growth and development of rat neonates. newborn rats were given daily subcutaneous injections of 300 or 500 mg kg-1 dfmo and killed after 7, 14, 21, and 28 days of treatment. pancreatic weights and dna, rna, protein, amylase and chymotrypsin total contents (per pancreas) and concentrations were evaluated at the end of each period. inhibition of body wei ... | 1987 | 3114741 |
| characterization and cloning of alloreactive t lymphocytes from pancreas allografts transplanted into diabetics. | 2011 | 3114928 | |
| delay of development of transmural irreversible ischaemic injury in canine myocardium. | during the course of experimentally induced myocardial ischaemia affected tissue initially suffers reversible ischaemic injury or, if ischaemia persists, injury of increasing severity before becoming irreversibly damaged. this state is characterized by tissue necrosis and referred to as myocardial infarction. the purpose of this study was to investigate whether it is possible to delay or perhaps even prevent the development of irreversible ischaemic injury. ischaemia was induced by coronary arte ... | 1987 | 3114945 |
| chorionic villi sampling: cytogenetic and clinical findings in 500 pregnancies. | the cytogenetic findings were analysed in a series of 500 pregnancies in which chorionic villi sampling was performed. in all cases a direct method was used, karyotyping being successful in 481 cases (96.2%). the main indication for sampling was maternal age over 36 (412 cases; 82.4%). abnormal laboratory findings resulted in 24 terminations of pregnancy (4.8%); in addition five unexpected balanced chromosome rearrangements were detected. twelve of 15 cytogenetic discrepancies were detected at a ... | 2011 | 3115477 |
| hypophosphataemia: a feature of malaria? | 1987 | 3115481 | |
| primary nursing. a modified approach to cost-effective quality care. | 2011 | 3115890 | |
| [central mechanisms of the development of ischemic disorders of heart rhythm]. | the activity of afferent and internuncial neurons of the bulbar cardiovascular centre (bcvc) was evaluated, using microelectrodes, in conditions of serotonin microinjections, altered blood gas composition and sensomotor cortical stimulation, in acute experiments in cats and rabbits. the afferent flow from ischemized myocardium was examined at the level of nodular-ganglion neurons. cortical stimulation, changed blood o2 and co2 proportions and the afferent message related to impaired coronary flo ... | 1987 | 3116317 |
| [comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria]. | the susceptibility has been determined of 169 shigella spp., 93 salmonella spp., 68 yersinia enterocolitica, 34 vibrio cholerae 0:1, and 34 campylobacter jejuni, isolated in central africa and in belgium, to ten fluoroquinolones: ciprofloxacin, ofloxacin, norfloxacin, pefloxacin, enoxacin, amifloxacin, ci-934, a-56619, a-56620 and ro 23-6240. all quinolones were active against the strains tested, showing an mic90 between 0.004 mg/l and 2 mg/l for strains susceptible to nalidixic acid and an mic9 ... | 1987 | 3116489 |
| intestinal epithelial function and villus surface area in rats with bile fistulae. | we have previously found reduced absorption of vitamin b12 in rats with choledochocolic fistulae. to investigate whether the reduction is caused by epithelial dysfunction or mucosal hypoplasia, choledochocolic fistulae were made in 11 rats, whereas 10 rats were sham-operated. the epithelial function was evaluated 9 days later by measuring the uptake of 57cob12 and glucose in perfused intestinal segments and by determining the activities of 11 mucosal enzymes. hypoplasia was investigated by perfo ... | 1987 | 3116662 |
| effect of anaemia on fetal acid-base status. | in 79 pregnancies with erythroblastosis fetalis, fetal blood was sampled to assess the level of anaemia. significant correlations were found between the haemoglobin concentration and umbilical artery ph, bicarbonate concentration and base excess. compensatory mechanisms help to maintain oxygen supply in anaemia but their failure is associated with hydrops fetalis. | 2011 | 3117096 |
| pseudoatrophy of the brain with valproic acid monotherapy. | a patient is described who, while on valproic acid monotherapy, developed reversible shrinkage of the brain, documented by computerized tomography with associated cognitive deficit. although pseudoatrophy has been reported with steroid therapy, this is the first implication of an anticonvulsant drug in the etiology of that condition. | 2011 | 3117347 |
| intravenous therapy: expanding the bounds of safety. | 2011 | 3118063 | |
| acute phase reaction following chemotherapy. | 2011 | 3118119 | |
| antimicrobial activity of lysozyme against bacteria involved in food spoilage and food-borne disease. | egg white lysozyme was demonstrated to have antibacterial activity against organisms of concern in food safety, including listeria monocytogenes and certain strains of clostridium botulinum. we also found that the food spoilage thermophile clostridium thermosaccharolyticum was highly susceptible to lysozyme and confirmed that the spoilage organisms bacillus stearothermophilus and clostridium tyrobutyricum were also extremely sensitive. several gram-positive and gram-negative pathogens isolated f ... | 1987 | 3118808 |
| [the structure of products of modification of nucleotides and dna by ethyleneimine and thio-tepa]. | previously undescribed products of dgmp, gmp, amp, dcmp and tmp aminoethylation by ethylenimine and n,n',n"-triethylenethiophosphoamide (thio-tepa) have been obtained and shown to be aminoethyl esters of nucleotides with the free or substituted amino group. in case of dgmp and gmp ethylenimine and tio-tepa alkylate not only phosphate but also the base residue at the n7 position. the 7-aminoethyl derivatives of dgmp and gmp, which thio-tepa afforded, were characterized whereas the corresponding e ... | 2011 | 3118884 |
| specific reduction of n,n-dimethylnitrosamine mutagenicity in drosophila melanogaster by dimethyl sulfoxide. | dimethyl sulfoxide (dmso) used as a solvent has been observed to complicate mutagenicity screens by interacting with tested chemicals to yield false positives or negatives. we have used dmso as a solvent in the drosophila melanogaster recessive sex-linked lethal mutation assay and find that it reduces, but does not abolish, the detectable mutagenicity of n,n-dimethylnitrosamine (dmn). its use as a solvent with procarbazine, another promutagen, shows no effect on mutagenicity in drosophila. dmso ... | 2011 | 3119334 |
| novel transcripts from the ultrabithorax domain of the bithorax complex. | we present a detailed analysis of the transcriptional products of the bithoraxoid (bxd) region of the ultrabithorax domain in the bithorax complex of drosophila melanogaster. this region is transcribed twice during development: between 3 and 6 hr of embryogenesis, a set of early transcripts, 1.1 to 1.3 kb in size, is synthesized; from the midthird larval instar through the adult stages, a late 0.8-kb transcript is synthesized. we have sequenced five cloned cdnas representing early transcripts an ... | 2010 | 3119423 |
| refractive surgery. | 2011 | 3120886 | |
| eczema after intravenous infusion of immunoglobulin. | 2011 | 3120918 | |
| how best to use nitrates. | 2011 | 3120926 | |
| sequential antibiotic therapy in acute leukemia. | 2011 | 3121466 | |
| combined effects of the mycotoxins aflatoxin b1 and cyclopiazonic acid on sprague-dawley rats. | this study was conducted to determine whether exposure to cyclopiazonic acid (cpa) and aflatoxin b1 (afb1) would alter the toxicity associated with exposure to either toxin individually. groups of male rats were administered 0, 0.1 or 4.0 mg cpa/kg body weight/day intragastrically (three groups per dose level) for three consecutive days and 30 min after each of these cpa doses the rats were dosed by gavage with 0, 0.1 or 2.0 mg afb1/kg body weight/day. six of the 12 rats given each of these nine ... | 1987 | 3121482 |
| forecasting client transitions in british columbia's long-term care program. | this article presents a model for the annual transitions of clients through various home and facility placements in a long-term care program. the model, an application of markov chain analysis, is developed, tested, and applied to over 9,000 clients (n = 9,483) in british columbia's long term care program (ltc) over the period 1978-1983. results show that the model gives accurate forecasts of the progress of groups of clients from state to state in the long-term care system from time of admissio ... | 2010 | 3121537 |
| antibody to trypanosoma cruzi neuraminidase enhances infection in vitro and identifies a subpopulation of trypomastigotes. | a rabbit antibody to the neuraminidase of the infective form of trypanosoma cruzi identifies a subpopulation of trypomastigotes that expresses neuraminidase. complement-mediated lysis by the antibody selectively destroys 30 to 40% of the trypomastigotes, supporting the conclusion that the immune antibody binds to a subset of parasites. the trypomastigotes that react with the immune antibody are the only ones expressing neuraminidase because the trypomastigotes that survive complement-mediated ly ... | 1988 | 3121750 |
| trials of furazol and some other drugs in intestinal amoebiasis. | 2011 | 3121763 | |
| purification of an octamer sequence (atgcaaat)-binding protein from human b cells. | the highly conserved octamer sequence atgcaaat or its inverse complement found in all human and murine immunoglobulin gene promoters has been demonstrated to be necessary in the lymphoid-specific transcription by deletion analysis. trans-acting factors that interact with the octamer motif are thought to be involved in this tissue-specific expression. using a gel mobility shift assay, we have identified both lymphoid-specific and ubiquitous nuclear factors that interact with a human gamma 1 heavy ... | 1987 | 3122182 |
| mucosal and serum immunity following commensal enteric colonization. | 1987 | 3122537 | |
| encainide-induced hyperglycemia. | twenty-three patients were treated for at least one month with encainide, a new antiarrhythmic drug. no patient was treated for hyperglycemia prior to encainide therapy. during encainide administration, five episodes of marked hyperglycemia (serum glucose level greater than or equal to 200 mg/dl) developed in four patients. (one patient received encainide twice.) the mean pretreatment glucose level was 190 +/- 69 mg/dl and rose to 397 +/- 163 mg/dl after one month of encainide therapy in patient ... | 2011 | 3122563 |
| effects of methylprednisolone on acute lung paraquat toxicity in sheep. | infused into sheep, paraquat causes increased flow of protein-rich lung lymph, increased prostanoid production, and neutrophil accumulation in the lung. the effects of high-dose methylprednisolone on the response to paraquat infusion were studied in awake sheep with chronic lung lymph fistulas. seven sheep were infused with paraquat (30 mg/kg) alone. six sheep received methylprednisolone (1.0 g plus 0.5 g/h intravenously), beginning 30 min before paraquat (pretreatment), and 5 received methylpre ... | 1988 | 3122611 |
| [fibrous lesions of the skeleton in infants and children]. | 2011 | 3122625 | |
| [24-hour efficacy of a system of transcutaneous administration of nitroglycerin. evaluation by the exercise test and gamma angiography]. | the effects of a nitroglycerin transdermal therapeutic system (tts ng 10 mg/24 h) 24 hours after application were evaluated by exercise left ventricular radionuclide cineangiography. 20 patients with ischemic heart disease were included in a double-blind, within patient, acute study comparing tts ng to placebo. were measured: exercise-test parameters and global (ef) and regional (ref) ejection fractions at rest and during exercise. at maximum load, the double product rose from 18,680 +/- 4,118 w ... | 2011 | 3122628 |
| differential effects of 15-hpete on arachidonic acid metabolism in collagen-stimulated human platelets. | the 15-hydroperoxyeicosatetraenoic acid (15-hpete) has been shown to affect platelet aggregation induced by collagen, arachidonic acid (aa), and pgh2-analogue. furthermore, it also inhibits the platelet cyclooxygenase and lipoxygenase enzymes, and prostacyclin synthase. the present study was designed to test the effect of 15-hpete on the mobilization of endogenous aa in collagen-stimulated human platelets. for this purpose, human platelets pretreated with bw755c (a dual inhibitor of cyclooxygena ... | 1988 | 3122753 |
| rescue of menotrophin cycles prone to develop ovarian hyperstimulation. | in an attempt to prevent the loss of 'overstimulated cycles' associated with human menopausal gonadotrophin (hmg)-induced ovulation, oestradiol levels and ovarian follicular state were monitored in 12 women with 'overstimulated cycles' after withholding hmg for several days. human chorionic gonadotrophin (hcg) was administered when oestradiol levels were less than or equal to 1700 pg/ml and the leading follicles between 17 and 22 mm in diameter. during the withholding period follicular growth co ... | 1987 | 3122819 |
| plasmids in bacteria exposed to activated neutrophils mediate mutagenesis when transferred to new hosts. | the plasmid puc18 contains a lacz alpha-complementation gene that codes for a small peptide that can complement the delta m15 mutation of the escherichia coli lacz (beta-galactosidase) gene, converting bacteria carrying that mutated gene from the lacz- to the lacz+ phenotype. this plasmid was used in experiments designed to study mutagenesis by human neutrophils. e coli carrying puc18 were incubated with neutrophils under conditions in which little ingestion of the bacteria took place; the plasm ... | 1988 | 3122860 |
| extracorporeal gas exchange in acute respiratory failure. | 2011 | 3122975 | |
| characterization of the pseudomonas aeruginosa reca gene: the les- phenotype. | the les- phenotype (lysogeny establishment deficient) is a pleiotropic effect of the lesb908 mutation of pseudomonas aeruginosa pao. lesb908-containing strains are also (i) deficient in general recombination, (ii) sensitive to uv irradiation, and (iii) deficient in uv-stimulated induction of prophages. the p. aeruginosa reca-containing plasmid pkml3001 complemented each of these pleiotropic characteristics of the lesb908 mutation, supporting the hypothesis that lesb908 is an allele of the p. aer ... | 1988 | 3123459 |
| isolation of salmonella using three selective enrichment broths from sausages naturally contaminated. its relationship with other microorganisms that produce food toxi-infections. | recently a great number of cases of human salmonellosis has been observed, and contaminated foods are the most important source of gastro-intestinal diseases by salmonella. a comparative study of the efficiency of salmonella spp. isolation from different kinds of sausage was carried out, using selenite-cystine (sc), müller-kauffmann tetrathionate (mk) and rappaport-vassiliadis (rv/43) broths. in addition, other microorganisms that produced food toxi-infections were investigated. the percentage o ... | 1987 | 3124372 |
| [potential use of serological methods in detecting cholera toxin]. | in the study of 50 vibrio cholerae museum strains, 45 of them producing cholerigenic effect in suckling rabbits, cholera toxin, determined by means of the passive immune hemolysis (pih) test, has been detected in the supernatant of the culture fluid of only two strains: v. cholerae 569 b, a well-known producer of cholera toxin, and v. cholerae (eltor) 1310, from whose population a toxigenic variant has been obtained by selection. to study the capacity of v. cholerae for producing toxin in vitro, ... | 1987 | 3124418 |
| study protocol: a randomized clinical trial of total parenteral nutrition in malnourished surgical patients. | csp #221 is a randomized multiinstitutional clinical trial to assess the efficacy of 10 d of perioperative total parenteral nutrition (tpn) in reducing morbidity and mortality in malnourished patients undergoing intraperitoneal and/or intrathoracic operations. in this paper a detailed protocol for the clinical efficacy trial is presented primarily as a reference document for use in interpretation of the results of the clinical trial. it is also anticipated, however, that review of this protocol ... | 2011 | 3124598 |
| inhibition of adenylate cyclase from luteinized rat ovary by monovalent cations: roles of the stimulatory guanine nucleotide-binding regulatory component and stimulatory hormone receptor. | sodium and other monovalent cations (added as chloride salts) inhibited adenylate cyclase of luteinized rat ovary. sodium chloride (150 mm) inhibited basal enzyme activity by 20%. sodium chloride inhibition was enhanced to 34-54% under conditions of enzyme stimulation by guanine nucleotides (gtp and its nonhydrolyzable analog 5'-guanylyl imidodiphosphate), fluoride anion, and agonists (ovine luteinizing hormone (olh) and the beta-adrenergic catecholamine isoproterenol) acting at stimulatory rece ... | 1988 | 3124764 |
| epidermal growth factor, but not thyrotropin, stimulates the expression of c-fos and c-myc messenger ribonucleic acid in porcine thyroid follicle cells in primary culture. | previous studies have shown that tsh stimulates functional parameters in cultures of porcine follicle cells, but has no stimulatory effect on their growth. epidermal growth factor (egf), on the other hand, is a potent mitogen in such cells. the aim of the present investigation was to study the effect of egf and tsh on the expression of proto-oncogene mrna in porcine thyroid follicle cells. the addition of egf caused a marked increase in the c-fos and c-myc mrna levels. stimulation of cells with ... | 1988 | 3125035 |
| hip pain in an anticoagulated patient. | 2011 | 3125206 | |
| regulation of ige synthesis in atopic disease. | 2011 | 3125207 | |
| man's place in hominoidea as inferred from molecular clocks of dna. | divergence dates among primates were estimated by molecular clock analysis of dna sequence data. a molecular clock of eta-globin pseudogene was calibrated by setting the date of divergence between catarrhini and platyrrhini at 38 million years (myr) ago. the clock gave dates of 25.3 +/- 2.4, 11.9 +/- 1.7, 5.9 +/- 1.2, and 4.9 +/- 1.2 myr ago ( +/- refers to standard error) for the separation of rhesus monkey, orangutan, gorilla, and chimpanzee, respectively, from the line leading to humans. in p ... | 1987 | 3125331 |
| [magnetic resonance imaging in dissection of the aorta]. | in order to evaluate the usefulness of this new exploratory method in dissection of the aorta, 13 patients (10 men and 3 women, mean age 58 +/- 14 years) were examined by means of an 0.5 tesla magniscan 5000 nuclear magnetic resonance machine. fifteen examinations were performed: 5 in patients with actual aortic dissection (type a 4 including one acute, type b1), 5 in patients previously operated upon for type a dissection and 5 for suspected acute aortic dissection unconfirmed by other examinat ... | 2011 | 3125805 |
| early treatment of adult respiratory distress syndrome with positive end-expiratory pressure. | 2011 | 3126425 | |
| renal aspergilloma--a case illustrating the problems of medical therapy. | the second documented case of renal aspergilloma due to aspergillus flavus is presented. the merits of the medical therapy that failed are discussed. pathological examination showed a nidus of aspergillus around suture material persisting from a pyelolithotomy operation 2 years before in india. we argue that this was the reason for the failure of the medical therapy. this is the first case of its kind reported. | 1987 | 3126459 |
| herpes zoster, postherpetic neuralgia, and interferon-gamma. | 2011 | 3126691 | |
| an interleukin 2 binding factor in human serum. | 1988 | 3127085 | |
| [enterostoma therapy--a pilot course in the essen education center of the german nursing association]. | 2011 | 3127632 | |
| disease and non-battle injuries among u.s. marines in vietnam. | 2011 | 3127752 | |
| the ideological construction of risk: an analysis of corporate health promotion programs in the 1980s. | the nature of theoretical knowledge about health promotion and disease prevention programs at the worksite is examined in the context of knowledge as ideological construction. the emergence of the discourse about health promotion is linked to corporate attempts to reduce their share of medical expenditures and solve problems of productivity and absenteeism which plague the american workforce. although not always evident, corporate managers choose selectively from a body of knowledge about medica ... | 2011 | 3127894 |
| association between o blood group and occurrence and severity of diarrhoea due to escherichia coli. | during studies of diarrhoea due to escherichia coli in 316 adult volunteers, abo and rh blood group determinations were done to look for differences in the occurrence or severity of illness in association with certain blood groups. in studies using heat-labile enterotoxin-producing e. coli, volunteers with o blood group had a significantly higher attack rate for diarrhoea than persons with other blood groups. in contrast, in studies with enteropathogenic or heat-stable enterotoxin-producing e. c ... | 1987 | 3127953 |
| human antibody responses against schistosomal antigens. i. antibodies from patients with ancylostoma, ascaris lumbricoides or schistosoma mansoni infections react with schistosome antigens. | sera of patients with either hookworm infections or ascariasis, who are from areas nonendemic for schistosoma mansoni, contain antibody reactivity against extracts of s. mansoni schistosomula. such patients with hookworm, but not those with ascaris lumbricoides, also express considerable antibody activity against intact schistosomula and schistosomular membrane preparations. sera from patients with schistosomiasis mansoni also contain these activities. because these three helminthic infections o ... | 1988 | 3128128 |
| antinuclear antibody-negative systemic lupus erythematosus (sle) and severe renal involvement: close correlation between disease activity and appearance of circulating anticoagulant. | a 16-year-old girl meeting the criteria for sle is described. salient features of the clinical course included active glomerulonephritis with dense subepithelial deposits on electron microscopy, pulmonary embolism, axillary vein thrombosis, arthritis, serositis and fever. disease activity correlated with the presence of lupus anticoagulant as measured by vdrl and partial thromboplastin time (ptt). her serum was consistently negative to ana, anti-ds-dna, anti-ss-dna, ena, anti-ro, anti-la, and le ... | 2007 | 3128493 |
| low trh-tsh responses in human essential hypertension. | thirty female and male essential hypertensive patients and eighteen normotensive controls were submitted to the trh-tsh conventional test (200 ug intravenously, bolus injection of trh). supramaximal doses of 400 and 600 ug were repeated with a week interval to each subject. hypertensives showed a significant lower response to both conventional and supramaximal trh doses. hypothalamic-pituitary-thyroid axis abnormalities, secondary to trh-receptor alterations, could account for this result. | 1988 | 3129219 |
| clinical findings in 12 patients with mps iv a (morquio's disease). further evidence for heterogeneity. part ii: dental findings. | typical dental changes were present in all cases, although they were of variable degree. however, the tooth morphology would appear to be highly specific for mps iv a, and is not found in mps iv b (beta-galactosidase deficiency) or the recently delineated mps iv c (enzyme defect unknown). thus the dental changes have a very useful diagnostic potential in mild atypical cases of mps iv a, although they may only be demonstrable radiologically in some such cases. | 2011 | 3129222 |
| the omega-hydroxylation of arachidonic acid by human polymorphonuclear leukocytes. | incubations of [1-14c]arachidonic acid with unstimulated human polymorphonuclear leukocytes resulted in the formation of four new metabolites in a previously described reverse-phase hplc system. three of these metabolites were largely suppressed in a co/o2 (80/20, by vol.) atmosphere indicating a cytochrome-p450-dependent monooxygenase reaction. in agreement with this assumption is their nadph/o2-dependent formation in the microsomal fraction. one metabolite was identified by gas chromatography/ ... | 1988 | 3129296 |
| dental service in a geriatric institution. | 2011 | 3129461 | |
| effects of calcium ionophore, a23187 and calmodulin inhibitors on intercellular communication in the rat myometrium. | we have studied the effect of a calcium ionophore, a23187, and the purported calmodulin inhibitors, calmidazolium and chlorpromazine, on direct intercellular communication between smooth muscle cells in the myometrium of delivering rats. the extent of cell-to-cell coupling was determined by exposing one portion of small strips of longitudinal myometrium to 2-[3h] deoxy-d-glucose (2-dg) and determining the distribution and apparent diffusion coefficient (da) for this tracer after a 5-h period for ... | 1988 | 3130110 |
| survival of pathogenic bacteria in environmental microcosms. | the survival times of salmonella enteritidis, pseudomonas aeruginosa, staphylococcus aureus, and vibrio cholerae in natural soil and river water samples were monitored by using various differential media. s. aureus and v. cholerae failed to survive in samples of soil, groundwater, and river water with various degrees of eutrophication. the population of the introduced s. enteritidis remained fairly constant in all three samples of soils tested. in water samples, numbers of s. enteritidis and p. ... | 1987 | 3130237 |
| synergistic activation of human t cells by interleukin 1 and interleukin 6. | purified human interleukin 6 (il 6) was found to stimulate the proliferation of human tonsillar and peripheral rosetting t cells subliminally activated with phytohemagglutinin (pha). this response seemed independent of il 2 but highly dependent on the presence of accessory cells. indeed, when accessory cell-depleted tonsillar t cells were activated with pha and exposed to il 6, only minimal proliferations were observed. a similar result was obtained with il 1. however, a combination of these two ... | 1988 | 3130269 |
| human rabies--california, 1987. | 1988 | 3130561 | |
| comparative observations of fever and associated clinical haematological and blood biochemical changes after intravenous administration of vibrio cholerae enterotoxin, staphylococcal enterotoxins and escherichia coli endotoxin in goats. | 1988 | 3130732 | |
| anomeric specificity of d-glucose metabolism in human erythrocytes. | the metabolism of d-[5-3h]glucose and d-[u-14c]glucose displays anomeric specificity in human erythrocytes. at close-to-physiological hexose concentrations, pure beta-d-[5-3h]glucose is metabolized at a higher rate than the corresponding pure alpha-anomer in most, but not all, subjects. this situation represents a mirror image of that found in rat erythrocytes. the anomeric preference is modulated by the extracellular concentration of d-glucose and may differ for distinct metabolic variables. th ... | 1988 | 3131049 |
| characterization of prolactin-releasing factor in the rat posterior pituitary. | we previously reported that the rat posterior pituitary contains a potent prl-releasing factor (prf) which is distinct from oxytocin (ot), trh, and angiotensin ii (aii). the objectives of this study were 1) to examine whether posterior pituitary extracts stimulate prl release in the presence of dopamine (da), 2) to determine the chemical nature of prf, and 3) to estimate its mol wt. perifused anterior pituitary cells were used to assess prf activity. posterior pituitaries and medial basal hypoth ... | 1988 | 3131118 |
| gonadotropin-releasing hormone molecular forms in mammalian hypothalamus. | multiple forms of gnrh have been detected in brain tissue of species from all nonmammalian vertebrate classes, but in mammals it is generally believed a single molecular form of gnrh is present. we have investigated the possibility that additional structural variants of gnrh are present in mammalian (sheep, rat, and human) hypothalamus. hypothalami were extracted with acetic acid and subjected to gel filtration chromatography and reverse phase hplc systems specifically designed to separate gnrh ... | 1988 | 3131123 |
| preliminary observations on alterations in prolactin, gonadotropins, e2-17b & progesterone in patients with breast cancer. | 2011 | 3131240 | |
| kinetic analysis of the ca2+-dependent, membrane-bound, macrophage phospholipase a2 and the effects of arachidonic acid. | the kinetics of the ca2+-dependent, alkaline ph optimum, membrane-bound phospholipase a2 from the p388d1 macrophage-like cell line were studied using various phosphatidylcholine (pc) and phosphatidylethanolamine (pe) substrates. this enzyme exhibits "surface dilution kinetics" toward pc in triton x-100 mixed micelles, and the "dual phospholipid model" was found to adequately describe its kinetic behavior. with substrate in the form of sonicated vesicles, the dual phospholipid model should give r ... | 2011 | 3131322 |
| journal reports--a unit event. | 2011 | 3131395 | |
| valproate-associated hepatotoxicity and its biochemical mechanisms. | intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ... | 2011 | 3131628 |
| imported human rabies--australia, 1987. | 1988 | 3131653 | |
| class switching from gamma 3 to gamma 2b in a murine pre-b cell line. | class switching from gamma 3 to gamma 2b production at pre-b cell stage was observed in an abelson virus-transformed murine immature cell line that is able to perform vh to djh recombinations followed by class switch recombinations. a series of southern blotting experiments indicates that the class switching from gamma 3 to gamma 2b was mediated by the deletion mechanism of the intervening ch genes on the expressed chromosome and that the break points in the switch recombinations might be differ ... | 1988 | 3131665 |
| [control of growth hormone release by growth hormone-releasing factor and prostaglandin e2 in a system of perfused rat anterior pituitary cells]. | using superfused rat pituitary cells we showed that the growth hormone-releasing factor (grf) and prostaglandin e2 (pge2) increased growth hormone (gh) secretion in a similar manner in terms of kinetics and amplitude of responses. moreover, our data suggest that they stimulate gh secretion mainly by camp-dependent mechanisms. | 1988 | 3131855 |
| evaluation of the polychlorobiphenyl aroclor 1254 in an animal model of atherosclerosis. | 2010 | 3132110 | |
| grand mal seizure after extradural morphine analgesia. | following an elective caesarean section under extradural anaesthesia, a 30-yr-old known epileptic woman (gravida 4, para 3) developed a tonic-clonic seizure, 6 h after the administration of morphine 3 mg into the extradural space. possible aetiological factors are discussed. | 2011 | 3132194 |
| total parenteral nutrition for the treatment of severe hyperemesis gravidarum: maternal nutritional effects and fetal outcome. | hyperemesis gravidarum is a complication of pregnancy that can lead to severe maternal nutritional deprivation. total parenteral nutrition has been used in pregnancy complicated by hyperemesis gravidarum. however, little has been done to study the nutritional aspects of hyperemesis or the maternal effects of total parenteral nutrition when given during the first trimester of pregnancy. the purpose of this study was to examine the nutritional state of pregnancy complicated by hyperemesis gravidar ... | 2011 | 3132667 |
| ethics of fetal brain cell transplants. | 2011 | 3133017 | |
| surgical aspects of drug smuggling. | 2011 | 3133033 | |
| departmental divisions and the crisis in undergraduate medical education. | 2011 | 3133048 | |
| hospital visiting hours: time for improvement. | in a survey of hospital visiting hours in general medical and surgical wards throughout the united kingdom a pattern of visiting emerged showing that many hospitals still have very restricted visiting. a quarter of the 404 hospitals that responded permitted visiting for an average of two hours a day or less. in contrast, just over a third of hospitals allowed visiting for more than five hours a day. there was no relation between visiting times and type of hospital, but a striking regional variat ... | 2011 | 3133059 |
| drug addicts and the gp. | 2011 | 3133066 | |
| risk of upper respiratory tract infection and malaria prophylaxis. | 2011 | 3133070 | |
| inhibition of 7,12-dimethylbenz[a]anthracene-induced genotoxicity in chinese hamster ovary cells by retinol and retinoic acid. | the effects of retinol and retinoic acid on cytotoxicity and mutation expression at the hypoxanthine-guanine phosphoribosyl transferase (hgprt) locus in chinese hamster ovary (cho) cells with or without exogenous metabolic activation were studied in the presence and absence of known chemical mutagens. neither retinol nor retinoic acid induced mutants at the hgprt locus of cho cells at concentrations ranging from 1 microm to 50 microm without exogenous metabolic activation, and at concentrations ... | 1988 | 3133130 |
| current trends in enteral feeding. | 2011 | 3133160 | |
| all-trans retinoic acid with or without low dose cytosine arabinoside in acute promyelocytic leukemia. report of 6 cases. | 2011 | 3133168 | |
| theoretical and practical considerations in the doubly-labelled water (2h2(18)o) method for the measurement of carbon dioxide production rate in man. | in the doubly-labelled water (2h2(18)o) method for the measurement of carbon dioxide production rate in man, single exponential disappearance curves for 2h2o and h2(18)o in body water are used; the precision with which the slopes and intercepts of the curves are estimated determines the precision of the estimate of carbon dioxide production rate. in studies with infants, and in computer simulations, the effect of different experimental regimes on the overall precision of the carbon dioxide produ ... | 1988 | 3133206 |
| selective terminal alpha 2-3 and alpha 2-6 sialylation of glycosphingolipids with lacto-series type 1 and 2 chains in human meconium. | human meconium was found to contain two kinds of gangliosides with the same carbohydrate sequence belonging to the lacto-series. they were detected by tlc-immunostaining with monoclonal antibodies directed to the neuac alpha 2-6gal and lc4cer structures. one of these two gangliosides, a major one, which migrated on tlc to a position below that of standard iv3neuacnlc4cer from human erythrocytes, reacted with the antibody to neuac alpha 2-6gal. the other minor one, which migrated on tlc to a posi ... | 1988 | 3133241 |
| framework of a protocol for the evaluation of prenatal screening procedures: economic aspects. | 2011 | 3133257 | |
| [the overwhelmed intestine syndrome]. | we studied 54 patients who, after small intestinal resection, developed a massive protracted diarrhea with a daily fecal loss greater than 2 kg, status we defined as the "overwhelmed intestine syndrome" (ois). median length of residual small bowel was 120 cm, 19 patients had a definitive stoma (jejunostomy, n = 9; colostomy, n = 10), 26 patients had a provisional jejunostomy. fecal weight greater than 2 kg was related to enteral hyperalimentation (greater than 3,500 kcal) in 19 patients (induced ... | 2011 | 3133276 |
| the role of percutaneous endoscopic gastrostomy in enteral feeding. guidelines for clinical application. | 2011 | 3133279 | |
| biosynthesis of porphyrins and left ventricle function in patients with terminal renal insufficiency. | 2011 | 3133291 | |
| mitomycin-induced prophage induction in vibrio cholerae cells. | 1987 | 3133305 |