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[molecular basis of human hereditary diseases caused by gene expression deficiency].the recent literature on the structure of mutant human genes determining the phenotypic expression of hereditary diseases is reviewed. the main types of gene mutations are described including deletions and insertions, mutations impairing translation and posttranslational protein processing, m-rna processing, causing transcription blocks, ultimate or partial quantitative deficiency in proteins-gene products. the problems of genetic heterogeneity of hereditary diseases and diagnosis of the latter ...19883057356
criteria for an increased specificity of mri interpretation in elderly subjects with suspected multiple sclerosis.we reviewed the mris of 49 asymptomatic volunteers (age range, 31 to 77 years) and of 50 ms patients (age range, 14 to 63) for areas of increased signal (ais) and features discriminating ms lesions from lesions seen with normal aging. we obtained optimal specificity of mri interpretation (100%) if we required at least two of the following three ais features--size greater than or equal to 6 mm, abutting ventricular bodies, infratentorial location--for a positive mri diagnosis of ms. applying thes ...20113057397
a mutant human proinsulin is secreted from islets of langerhans in increased amounts via an unregulated pathway.a coding mutation in the human insulin gene (his-b10----asp) is associated with familial hyperproinsulinemia. to model this syndrome, we have produced transgenic mice that express high levels of the mutant prohormone in their islets of langerhans. strain 24-6 mice, containing about 100 copies of the mutant gene, were normoglycemic but had marked increases of serum human proinsulin immunoreactive components. biosynthetic studies on isolated islets revealed that approximately 65% of the proinsulin ...19883057496
a mutant human proinsulin is secreted from islets of langerhans in increased amounts via an unregulated pathway.a coding mutation in the human insulin gene (his-b10----asp) is associated with familial hyperproinsulinemia. to model this syndrome, we have produced transgenic mice that express high levels of the mutant prohormone in their islets of langerhans. strain 24-6 mice, containing about 100 copies of the mutant gene, were normoglycemic but had marked increases of serum human proinsulin immunoreactive components. biosynthetic studies on isolated islets revealed that approximately 65% of the proinsulin ...19883057496
current perspectives on the epidemiology and pathogenesis of clinically significant vibrio spp.recent taxonomic advances have now implicated several different vibrio species as human pathogens. while the most common clinical presentation of vibrio infection continues to be gastroenteritis, an increasing number of extraintestinal infections are being reported, particularly in immunocompromised individuals. detection of vibrio infections requires a good clinical history and the use of appropriate isolation and identification procedures by the laboratory to confirm illnesses attributed to vi ...19883058295
factors affecting the survival of pathogenic bacteria in subtropical river water.the present study was carried out to determine the factors causing the disappearance of introduced salmonella enteritidis, staphylococcus aureus, and vibrio cholerae in natural river water. when large numbers of the above organisms (final level 10(7)-10(8) cfu per ml) were added to river water, the decline of their numbers coincided with increasing numbers of protozoa. furthermore, their survival was improved dramatically if the river water was amended with a eucaryote inhibitor. after comparing ...19883058406
genetic fusion of a non-toxic heat-stable enterotoxin-related decapeptide antigen to cholera toxin b-subunit.a decapeptide highly homologous to the sta escherichia coli heat-stable enterotoxin and to several other heat-stable enterotoxins was fused genetically to the amino-end of the b-subunit of cholera toxin (ctb) and the hybrid protein gene expressed from a tacp overexpression system. the sta-related decapeptide used, which was encoded by a synthetic oligodeoxynucleotide, contained a single mutation which substituted a disulfide-linked cysteine by alanine. after its fusion to ctb the decapeptide was ...19883058509
general anesthetics. 20103058610
nonionic contrast agents and coagulation.the chemotoxicity of nonionic and ionic contrast media is discussed with reference to chemical structure. second-generation nonionic contrast media have the lowest chemotoxicity of any agents because of the uniform distribution of hydrophilic groups around the molecule, which mask the hydrophobic iodine atoms. previous investigations show that second-generation nonionic agents have the same qualitative hematologic effects as other contrast agents. the less marked quantitative hematologic effects ...20103058638
a precision alignment frame for endosseous post dental implants.the advantages of the precision alignment frame are that it (1) accurately positions and aligns the initial pilot drill at implant surgery, (2) has no adverse effects on the diagnostic cast, (3) eliminates the need for an incision or raising a flap when locating a submerged implant root for transmucosal connection, (4) consistently and accurately records the relation of the implant root to the radiograph, (5) permits long-term evaluation of the implant after restoration, (6) has components that ...20103058942
a precision alignment frame for endosseous post dental implants.the advantages of the precision alignment frame are that it (1) accurately positions and aligns the initial pilot drill at implant surgery, (2) has no adverse effects on the diagnostic cast, (3) eliminates the need for an incision or raising a flap when locating a submerged implant root for transmucosal connection, (4) consistently and accurately records the relation of the implant root to the radiograph, (5) permits long-term evaluation of the implant after restoration, (6) has components that ...20103058942
an epidemic of multiresistant salmonella typhimurium with a characteristic plasmid profile among calves in tokachi district, japan. 19883058996
rish. vii: cell surface patterns--association of like cells.like-cells associate to form various tissues, and it has been demonstrated that this specificity resides in the plasma membrane. membrane bound tissue specific antigens and enzyme substrate mechanisms have been considered to be involved in this phenomena, but these explanations are incomplete. it is proposed that like-cells identify each other by specific complementary cell-surface patterns. this complementarity results from cell division. that is, when cells divide, they give rise to a mirror i ...20103059143
morbidity and mortality of carotid endarterectomy under local anesthesia: a retrospective study.it has been shown that carotid endarterectomy reduces the incidence of stroke in patients with symptomatic extracranial occlusive vascular disease in the absence of major perioperative complications such as stroke or death. we present a retrospective study of 106 carotid endarterectomies performed under local anesthesia in 100 patients in whom transient ischemic attack (tia) or minor stroke had occurred. nonfatal stroke occurred in 2%, and tia occurred in 1%. there was no perioperative mortality ...20113059211
[leonardo da vinci and his physician-contemporaries]. 20113059261
influence of pontic material on alveolar mucosal conditions.the purpose of the present study was to investigate plaque accumulation and inflammatory changes in the mucosa beneath fixed bridge pontics of various materials, in patients cleaning the infrapontic space daily. fixed bridges with a tight but non-compressive contact to the mucosa in the pontic area and with interchangeable test specimens placed in the pontic base were constructed for five patients. during 4-wk periods the following materials were tested: alloys with a high or a low gold content, ...20103059449
identification and localization of a novel, cytoskeletal, centrosome-associated protein in ptk2 cells.antisera raised against centrin (salisbury, j.l., a.t. baron, b. surek, and m. melkonian. 1984. j. cell biol. 99:962-970) have been used, here, to identify a centrosome-associated protein with an mr of 165,000. immunocytochemistry indicates that this protein is a component of pericentriolar satellites, basal feet, and pericentriolar matrix of interphase cells. these components of pericentriolar material are, in part, composed of 3-8-nm-diam filaments, which interconnect to form a three-dimension ...19883060471
effect of dexamethasone on experimental escherichia coli mastitis in the cow.the effect of intramuscular administration of dexamethasone on milk production and on several clinical and hematologic indicators in cows with experimental escherichia coli mastitis was studied. two groups of three cows each were intramammarily inoculated with 20 x 10(5) cfu e. coli 0101 k99 f41 in rear quarters. immediately after inoculation one groups received 30 mg dexamethasone intramuscularly, whereas the other group was injected similarly with pyrogen-free saline. fourteen days later milk ...19883060491
occupational health issues for providers of care to patients with hiv infection.the perception that hiv is a highly contagious nosocomial pathogen persists despite a great deal of evidence to the contrary. however, health care workers are at a low but finite risk of occupational infection with the virus, particularly through accidental needle-stick inoculations with infected blood. universal blood and body fluid precautions minimize the risk of nosocomial transmission of a variety of pathogens, including hiv, and should be routinely employed by all health care workers for a ...19883060519
fungal infections in aids. cryptococcosis.cryptococcus neoformans, histoplasma capsulatum, and coccidioides immitis are the three fungi that regularly cause disseminated, life-threatening disease in patients with aids. cryptococcosis is the fourth most common opportunistic infection in patients with aids and results in meningitis or pneumonia or both, in most cases. in addition, there have been unusual focal infections described and even unexplained fever alone. in any patient at risk for hiv infection, routine screening tests should in ...19883060529
[management of patients with dilated cardiomyopathy]. 20103060659
[management of patients with dilated cardiomyopathy]. 20103060659
[echographic and radiographic aspects of a case of burkitt's lymphoma]. 20113060909
[statistical study of hydatid locations. apropos of 644 cases--1980-1988]. 20103061096
[statistical study of hydatid locations. apropos of 644 cases--1980-1988]. 20103061096
[pathogenicity factors of vibrio cholerae]. 19883061255
[characteristics of the protease activity of vibrio cholerae strains and mutants with various biological properties].the study of 65 v. cholerae strains and mutants revealed that protease activity was high in choleragenic strains and mostly low, sometimes even not manifested, in noncholeragenic strains. the use of inhibitors made it possible to determine three types of protease. choleragenic strains were found to possess all three types of protease, while in noncholeragenic strains only protease of type 1 was detected in very rare cases. in noncholeragenic hemolytic strains and mutants protease of type 3 and i ...19883061263
isolation and chemical analysis of 7-o-(2-amino-2-deoxy-alpha-d-glucopyranosyl)-l-glycero-d-manno-heptose as a constituent of the lipopolysaccharides of the udp-galactose epimerase-less mutant j-5 of escherichia coli and vibrio cholerae.methyl 7-o-(2-amino-2-deoxy-alpha-d-glucopyranosyl)-l-glycero-d-manno-hepto+ ++ pyranoside (1) was released from the lipopolysaccharide of the udp-galactose epimerase-less mutant j-5 of escherichia coli by methanolysis and isolated by high-voltage paper electrophoresis. its chemical structure was determined by chemical analysis, deamination with nitrous acid, g.1.c.-m.s., and 1h- and 13c-n.m.r. spectroscopy performed on its acetylated derivative. the disaccharide moiety of 1 was also detected in ...19883061645
[two cases of retroperitoneal lymphangioma]. 20113062209
antipeptide monoclonal antibodies inhibit the binding of rabies virus glycoprotein and alpha-bungarotoxin to the nicotinic acetylcholine receptor.it has been reported that binding to muscle nicotinic acetylcholine receptor at the post-synaptic membrane is an important event of the rabies virus neurotropism. the binding site can be located within the 190-203 region of the virus glycoprotein sharing a high degree of homology with the "toxic loop" of the curare-mimetic snake neurotoxins. we have synthesized a tetradecapeptide corresponding to this glycoprotein region and used it, following conjugation with an immunogenic carrier to raise mab ...19883062388
microbial keratitis complicating penetrating keratoplasty.a retrospective review of 68 consecutive episodes of microbial keratitis complicating 66 penetrating keratoplasties (pks) showed major risk associations: suture-related problems (50%), contact lens wear (26%), previous herpes simplex infection (15%), graft failure (15%), and persistent epithelial defects (15%). topical steroid (85%) and antibiotic (59%) usage were common iatrogenic factors. half the infections occurred more than 1 year after grafting. bacterial infections involving gram-positive ...20083062538
associate degree nursing and the nursing home. 20113062574
[dysplastic nevus]. 20083062614
[dysplastic nevus]. 20083062614
the appearance of transferrin receptors on cultured human cytotrophoblast and in vitro-formed syncytiotrophoblast.using trypsinization and percoll gradient centrifugation, mononuclear cell populations were prepared from human term placentae. these populations consist mainly of cytotrophoblast, which probably lacks transferrin receptors. in vitro, transferrin receptors appear on these mononuclear cells and on syncytiotrophoblast formed in vitro, independently, of cellular fusion and proliferative state.19883062615
proceedings of the jerusalem meeting of the society for research into hydrocephalus and spina bifida, 1988. 20113062996
noninvasive ultrasound investigation of cerebral vessels in the case of vertigo and dizziness. 20113063093
mode of action of morpholine derivatives. 19883063169
neurologic monitoring.this article discusses the current methods for monitoring the intracranial environment in the critical care setting. intracranial pressure monitoring is discussed first. then the electroencephalogram and sensory evoked potentials are considered. finally, new techniques being evaluated are discussed.20113063351
dental implants: physiologic and clinical comparisons of fibro-osteal and osteal integration. 20103063602
dental implants: physiologic and clinical comparisons of fibro-osteal and osteal integration. 20103063602
glucose inhibits prostacyclin production by cultured aortic endothelial cells.a reduction in production of prostacyclin (pgi2) by the cells in the vascular wall may play a role in the pathogenesis of atherosclerosis in diabetic patients. the present study was undertaken to evaluate the effect of glucose on pgi2 production by endothelial cells in vitro. it was shown that pgi2 production by cultured bovine aortic endothelial cells was significantly reduced in the presence of a high concentration of glucose (300 mg/dl) compared with physiological concentrations of glucose (1 ...19883064357
the use of the transcendental meditation programme in the prevention of drug abuse and in the treatment of drug-addicted persons.the effectiveness of transcendental meditation (tm) in the prevention and reduction of drug abuse has been documented in many studies in the last 18 years. the programme is not a rehabilitation programme per se but is a means for self-development. thus, the resulting decrease in psychological problems and drug abuse is an automatic or secondary consequence of the practice of the meditation technique. since tm strengthens the individual and produces an overall and stable state of well-being, it n ...20113064844
clinical pharmacokinetics of anthelmintic drugs.a rational strategy for chemotherapy demands that dosage schedules be based on an adequate knowledge of clinical and biochemical pharmacology. many anthelmintic drugs (e.g. suramin, diethylcarbamazine, hycanthone) were introduced before modern techniques for drug evaluation (controlled clinical trials) and before the development of specific and sensitive analytical methods for the assay of drugs and metabolites in biological fluids. thus, many of the regimens used today for the treatment of para ...19883064952
[algodystrophies or post-traumatic dystrophies of reflex sympathetic origin]. 20113065796
emphasis on preventive perinatology: a suitable alternative for developing countries.the potential efficacy of preventive interventions in latin america to reduce perinatal morbidity and mortality is reviewed. the most important perinatal risk factors associated with pregnancy and delivery are young age of the mother, low socioeconomic status, low education, malnutrition, lack of prenatal care, pregnancy-induced-hypertension, perinatal infections, alcohol, smoking, and iatrogenic causes. adequate data are lacking to determine the magnitude of these factors in latin america. iatr ...20113065947
the expanding scope of pro review. explaining medicare's new review requirements in missouri. 20103067067
the expanding scope of pro review. explaining medicare's new review requirements in missouri. 20103067067
physiological adaptations to resistance exercise. implications for athletic conditioning.resistance training results in a wide spectrum of adaptations in various physiological systems. increases in muscle size and strength, changes in body composition, neuroendocrine function and cardiovascular responses have been observed following resistance training. additionally, resistance training may be an effective means by which the incidence of sports injuries can be reduced. the physiological alterations induced by resistance training appear to be specific to the number of sets and repeti ...20113067312
defective synthesis of apolipoprotein a-i in jejunal mucosa in coeliac disease.apolipoprotein a-i was studied in biopsy specimens from the duodenojejunal junction by means of an indirect immunoperoxidase technique. in normal control subjects apolipoprotein a-i was immunohistochemically detected only in the absorptive cells at the tips of villi and was mainly localized supranuclearly. in 14 patients with coeliac disease apolipoprotein a-i was virtually undetectable. this implies that the inflammatory lesion in coeliac disease decreases the intestinal mass of apolipoprotein ...20113067329
olsalazine in the treatment of active ulcerative colitis: a placebo controlled clinical trial and assessment of drug disposition.the efficacy, safety and disposition of olsalazine was assessed in patients with left-sided ulcerative colitis or proctitis in a double-blind placebo controlled trial. thirty patients with a mild-to-moderate attack of ulcerative colitis were randomly allocated to olsalazine capsules, 1 g b.d., or placebo for 6 weeks. good clinical response was found in six patients receiving olsalazine and in two receiving placebo. improvement in sigmoidoscopic findings and histological appearance of rectal biop ...20113067339
[problems of ambulatory treatment of patients with a transplanted kidney]. 20113067383
[pharmacokinetics of non-steroidal anti-inflammatory agents in the elderly]. 20113067421
[forensic medical service in the people's republic of bulgaria]. 20113067425
[use of photosensitizing preparations in the treatment of cancer of the orl organs]. 20113067440
is hysteroscopy of value in the investigation of female infertility?a prospective multicentre study was designed to ascertain the value of hysteroscopy in the evaluation of female infertility. the study comprises 619 co2 hysteroscopies in women complaining of infertility. four hundred and ninety nine examinations (80%) were performed without anaesthesia or cervical dilatation. twenty eight cases of malformation were diagnosed. adhesions were found in 68 patients (11%), polypi in 56 (9.1%) and submucous fibroids in 51 (8.2%). endometrial hyperplasia was diagnosed ...20113067483
[an abnormal origin of the ophthalmic artery arising from the middle meningeal artery]. 20103067497
[an abnormal origin of the ophthalmic artery arising from the middle meningeal artery]. 20103067497
alterations in the chemical composition and antigenicity of escherichia coli o89 lipopolysaccharide and lipid a after 60co gamma irradiation.the chemical composition and the antigenicity of escherichia coli lipopolysaccharide (lps) and lipid a were investigated after irradiation with 150 kgy 60co-gamma ray. compared to the original preparations, the irradiated lps showed a significant reduction in glucosamine, glucose and galactose and a decrease in the phosphate content. the fatty acid components were reduced to a smaller degree. irradiation induced a reduction in the antigenicity of the polysaccharide part. the amount of glucosamin ...19883067502
alterations in the chemical composition and antigenicity of escherichia coli o89 lipopolysaccharide and lipid a after 60co gamma irradiation.the chemical composition and the antigenicity of escherichia coli lipopolysaccharide (lps) and lipid a were investigated after irradiation with 150 kgy 60co-gamma ray. compared to the original preparations, the irradiated lps showed a significant reduction in glucosamine, glucose and galactose and a decrease in the phosphate content. the fatty acid components were reduced to a smaller degree. irradiation induced a reduction in the antigenicity of the polysaccharide part. the amount of glucosamin ...19883067502
epidemiological patterns and incidence of bio-, sero- and phage types of vibrio cholerae in hyderabad, india, during 1971-1984.during 1971-1984 out of 44,762 gastroenteritis cases bacteriologically examined, 4240 (9.5%) vibrio cholerae were isolated in hyderabad, india. out of them 1329 (31.3%) were classical and 2911 (68.7%) were el-tor biotypes. the changeover from classical to el-tor cholera was observed in hyderabad during 1975 and persisted. during this 14 year period four major outbreaks with v. cholerae serogroup o1 ogawa, v. cholerae biotype el-tor serogroup o1 ogawa were observed. phage types 1, 2 and 4 were pr ...19883067503
father's influence in the development of infant's relationships.recent research on the father infant interaction has challenged the long held belief that the "most important thing a father can do for his children is to love their mother". fathers have significant influences on the development of the infant's relationships both directly and indirectly. certainly his greatest indirect influence is through supporting, protecting, and facilitating the maternal infant dyad when it is the primary nurturing relationship. new research from a variety of perspectives ...20103067507
father's influence in the development of infant's relationships.recent research on the father infant interaction has challenged the long held belief that the "most important thing a father can do for his children is to love their mother". fathers have significant influences on the development of the infant's relationships both directly and indirectly. certainly his greatest indirect influence is through supporting, protecting, and facilitating the maternal infant dyad when it is the primary nurturing relationship. new research from a variety of perspectives ...20103067507
somatomedin c immunoreactivity in the achilles tendon varies in a dynamic manner with the mechanical load.distribution of the trophic peptide somatomedin c (sm-c; insulin-like growth factor i; igf-i) immunoreactivity was mapped in normal achilles and tibialis anterior tendons. the spindle-shaped tendon fibroblasts showed faint perinuclear staining. fibroblasts in the paratenon mostly had a more intense igf-i immunoreactivity, i.e. faint to moderate. when analysing either tendon in detail, areas with more intense igf-i immunoreactivity could be recognized and seemed to correlate with areas of high me ...19883067520
somatomedin c immunoreactivity in the achilles tendon varies in a dynamic manner with the mechanical load.distribution of the trophic peptide somatomedin c (sm-c; insulin-like growth factor i; igf-i) immunoreactivity was mapped in normal achilles and tibialis anterior tendons. the spindle-shaped tendon fibroblasts showed faint perinuclear staining. fibroblasts in the paratenon mostly had a more intense igf-i immunoreactivity, i.e. faint to moderate. when analysing either tendon in detail, areas with more intense igf-i immunoreactivity could be recognized and seemed to correlate with areas of high me ...19883067520
psychiatric and social problems among immigrants.high rates of mental morbidity among migrants are common but not universal. differences in rates may reflect factors in: (a) the country of origin; (b) the actual move; (c) the country of settlement. about 1.8 million people came to britain in 1950-1970 from the west indies and indian subcontinent. they resembled gastarbeiters in other european countries, except that as commonwealth citizens they had the right of permanent residence. with their children (many of whom are now adults) they are 3.5 ...20113067527
psychochemistry in psychiatry. papers presented in memory of ole j. rafaelsen. 20113067535
dopamine-regulated protein phosphorylation in the basal ganglia. 20113067550
sympathoadrenal medullary system and stress. 20113067552
physiological and behavioral aspects of stress in adolescence.gonadal and adrenal hormone levels appear to be linked to the stressors experienced by young adolescents. adjustment problems were accompanied by a profile of lower gonadal steroids and higher adrenal androgen levels, primarily androstenedione. later gonadal maturation may be a result of stress suppressing the reproductive axis. higher levels of androstenedione may be indicative of chronic levels of stress. however, the findings for androstenedione are complicated by the fact that androstenedion ...19883067560
the censorship of pornography: catharsis or learning?contemporary research on pornography reveals an impasse between the models of catharsis and learning. preference for the latter by a recent government report is based on ideological rather than scientific considerations. the breakdown in the liberal tradition, current pornography research based on behaviorism, and two major theoretical problems are discussed. the interface among psychology, sociology, and literary criticism is suggested as a positive direction for understanding pornography; cens ...20103067580
the censorship of pornography: catharsis or learning?contemporary research on pornography reveals an impasse between the models of catharsis and learning. preference for the latter by a recent government report is based on ideological rather than scientific considerations. the breakdown in the liberal tradition, current pornography research based on behaviorism, and two major theoretical problems are discussed. the interface among psychology, sociology, and literary criticism is suggested as a positive direction for understanding pornography; cens ...20103067580
assessment, management, and treatment planning for male adolescent sexual offenders.adolescent sexual offenders are considered as a part of the larger group of emotionally disturbed youngsters. for purposes of clinical management, areas of overlap between the two groups are identified and issues specific to sexual offenders are delineated. ethical issues, preventive interventions, the risk of recidivism, and the special problems presented by incestuous offenders are discussed.20103067582
assessment, management, and treatment planning for male adolescent sexual offenders.adolescent sexual offenders are considered as a part of the larger group of emotionally disturbed youngsters. for purposes of clinical management, areas of overlap between the two groups are identified and issues specific to sexual offenders are delineated. ethical issues, preventive interventions, the risk of recidivism, and the special problems presented by incestuous offenders are discussed.20103067582
implications of involuntary outpatient commitment for community mental health agencies.mental health laws regarding involuntary commitment are under pressure for reform in many states. one popular proposal is to use direct involuntary commitment to outpatient treatment without initial hospitalization or preventive detention. this article reviews the empirical evidence concerning this approach, and discusses administrative and policy implications for community mental health agencies that will bear the burden of such reform.20103067583
implications of involuntary outpatient commitment for community mental health agencies.mental health laws regarding involuntary commitment are under pressure for reform in many states. one popular proposal is to use direct involuntary commitment to outpatient treatment without initial hospitalization or preventive detention. this article reviews the empirical evidence concerning this approach, and discusses administrative and policy implications for community mental health agencies that will bear the burden of such reform.20103067583
genetic structure of the saguenay, 1852-1911: evidence from migration and isonymy matrices.the saguenay is a region in northeastern québec populated in the second half of the 19th century through migration from other parts of québec. the present-day population of nearly 300,000 is the result of both immigration and high rates of intrinsic growth. this population has been of interest to geneticists because of the high incidence of certain hereditary diseases, notably spastic ataxia, tyrosinemia, agenesis of the corpus callosum, vitamin d-dependent rickets, and myotonic dystrophy. paren ...20103067584
genetic structure of the saguenay, 1852-1911: evidence from migration and isonymy matrices.the saguenay is a region in northeastern québec populated in the second half of the 19th century through migration from other parts of québec. the present-day population of nearly 300,000 is the result of both immigration and high rates of intrinsic growth. this population has been of interest to geneticists because of the high incidence of certain hereditary diseases, notably spastic ataxia, tyrosinemia, agenesis of the corpus callosum, vitamin d-dependent rickets, and myotonic dystrophy. paren ...20103067584
captopril--a new approach for treatment of male subfertility? 20113067628
group b streptococcal infections. perinatal impact and prevention methods. 19883067638
an on-line detection system for aerosols of proteolytic enzymes. 20113067643
[ablation of 2 greenfield intracardiac filters]. 20113067649
alz 50 recognizes abnormal filaments in alzheimer's disease and progressive supranuclear palsy.the monoclonal antibody alz 50 recognizes a 68-kda protein present in large amounts in cerebral tissue of patients with alzheimer's disease (ad). we used light and electron microscopic as well as quantitative immunochemical techniques to compare distribution, characteristics, and amount of alz 50 antigen in the tegmental nuclei of the pons of subjects with progressive supranuclear palsy (psp) and subjects with ad. in both conditions alz 50 antigen was found in neurons with and without neurofibri ...20113067653
[melanoma of the glans penis: report of a case and review of the literature]. 20113067663
[academic dissertations of military pharmacists on the history of pharmacy]. 20113067684
monitoring of cardiac transplants with beta 2-microglobulin, cytoimmunological monitoring and endmyocardial biopsy: what's their value in detecting rejection? 20113067712
the 'bn2' gene, a regulator for the onset of chromosome condensation. 20113067728
operative anatomy and technique of radical parametrial resection in the surgical treatment of cervical cancer.wertheim's radical operation aimed, by removing the parametrial tissue far from the tumour, to achieve margins free of disease. the paratissues contain the lymphatic channels draining the cervix. they run to the pelvic wall and are interspersed by lymph nodes scattered throughout the parametrium. if lymphadenectomy is to be curative then the entire parametrium must be removed. to this end the resection of the cardinal ligament was pushed to its limit by dissection directly at the pelvic wall. th ...20103067946
operative anatomy and technique of radical parametrial resection in the surgical treatment of cervical cancer.wertheim's radical operation aimed, by removing the parametrial tissue far from the tumour, to achieve margins free of disease. the paratissues contain the lymphatic channels draining the cervix. they run to the pelvic wall and are interspersed by lymph nodes scattered throughout the parametrium. if lymphadenectomy is to be curative then the entire parametrium must be removed. to this end the resection of the cardinal ligament was pushed to its limit by dissection directly at the pelvic wall. th ...20103067946
the politics of birth control.by the time senate subcommittee hearings on the "population crisis" ended in 1968, a sizeable consensus had begun to emerge favoring government support of voluntary family planning programs at home and abroad. the goal to develop a national family planning program was easier to set than to accomplish, however, and there have been no lack of difficult questions to haggle over in the past 20 years. beginning with the johnson administration, the executive branch of government has tended to favor bl ...20113068073
hepatitis vaccines. 20113068135
biochemical and other markers of colon cancer.advances in the understanding of biochemical and molecular processes associated with cellular growth and differentiation, as well as colonic carcinogenesis hold promise for the development of new diagnostic and therapeutic modalities for this disease. altered glycosylation of cell surface and secreted glycoconjugates appear to be useful markers in differentiating normal from malignant colonic tissue. new information regarding deletion and inappropriate expression of several blood group-related c ...20113068143
kluyvera species soft tissue infection: case report and review.a soft tissue infection caused by kluyvera species in a previously healthy woman is described. successful treatment required incision and drainage of the wound in addition to administration of antibiotics. kluyvera species are indole positive, voges-proskauer negative members of the family enterobacteriaceae. previous reports of infection due to kluyvera species suggest that the organism is never more than an opportunistic pathogen; however, we report the first case of infection in a previously ...19883068255
[a case of pancreatic carcinoid tumor]. 20113068580
the history of hormone assays. 20103068672
stimulation of escherichia coli division by low-intensity monochromatic visible light. 19883068688
neck pain.six conditions cause most of the neck pain complaints seen by primary care physicians: cervical muscle strain or sprain, torticollis, acceleration injury, myofascial pain dysfunction syndrome, and cervical osteoarthritis or rheumatoid arthritis. most of them can be diagnosed and treated by the primary care physician. of the more unusual causes, one should not miss a clinical fracture; a herniated cervical disc, spinal cord compression from a disc, or epidural tumor; infection of the disc or the ...20103068689
[consequences of pyodestructive pyelonephritis in patients subjected to surgery during pregnancy]. 20113068874
history of medicine in alaska. 20113068995
[pharmacokinetic and toxicologic aspects of stress]. 20113069119
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