Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [acute hepatitis in childhood. study of 96 cases and 1-year follow-up]. | authors studied 96 children, 56 boys and 40 girls, aged 1 to 16 years, with acute viral hepatitis. 53 patients were diagnosed of hepatitis a virus (hav) detecting antibodies to hav of the igm class; 11 patients were diagnosed of hepatitis b virus (hbv) detecting serologic markers; 32 patients were diagnosed of non a-non b hepatitis. there were no serologic evidence of infection with cytomegalovirus and epstein-barr virus. they report an analytical and clinical comparative study of acute viral he ... | 1986 | 3103507 |
| [food of animal origin that is potentially infected and in danger of becoming infected by contact. (food hygiene consequences by the example of the occurrence of salmonella in meat of slaughtered animals and of hepatitis a viruses in mussels)]. | certain pathogenic micro-organisms in or on food of animal origin still constitute a particular hygienic risk. salmonellae are found chiefly on meat and in meat products including poultry. most of the infections with salmonellae in men are presumably caused by the consumption of raw products of animal origin. our stock of slaughter animals is most often latently infected. during the slaughter and the processing meat surfaces are contaminated with salmonellae. nevertheless a precautionary deconta ... | 1986 | 3107272 |
| epidemiological features of acute viral hepatitis among the israeli defence forces, 1977-83. | high morbidity rates of non-b hepatitis in the israeli defence forces has stimulated efforts towards its prevention. this paper analyses morbidity over a period of 7 years since a programme of pre-exposure prophylaxis with human normal immunoglobulin began. among 1480 cases studied, about 5% were of hepatitis b. in 360 patients further investigated 11% of illnesses were caused by hepatitis non-a non-b viruses; the remainder by hepatitis a virus. females comprised about 15% of all three groups. e ... | 1987 | 3108411 |
| prevention of endemic icteric viral hepatitis by administration of immune serum gamma globulin. | in a further analysis of a randomized, double-blind study of 107,803 u.s. soldiers receiving either immune serum gamma globulin (isg) or placebo, serum specimens from the first week of clinical illness from 210 soldiers consecutively hospitalized with icteric hepatitis were reexamined by using modern immunologic methods to test for evidence of hepatitis a and b. prophylactic intramuscular injection of 5 or 10 ml of isg containing antibody to hepatitis a virus and antibody to hepatitis b surface ... | 1987 | 3110307 |
| relation between non-a, non-b and delta hepatitis: studies with monoclonal antibodies. | to further investigate the specificity of the monoclonal antibodies (48-1 and s-1) associated with nanb hepatitis, extensive if studies were carried out on liver biopsy specimens from chimpanzees with experimental hepatitis a, b, nanb, or d, or from normal chimpanzees. both 48-1 and s-1 antibodies reacted in the same manner with liver biopsy specimens from 47 of 50 (94%) chimpanzees with acute or chronic nanb hepatitis and 15 of 18 (83%) chimpanzees with type d hepatitis. examinations of serial ... | 1987 | 3114765 |
| acute non-a, non-b hepatitis in kuwait. | in a prospective study of acute hepatitis in kuwait covering the period february 1983 to january 1984, a total of 1781 cases were diagnosed as having an acute viral hepatitis. 1,384 (77.7%) were found to be due to hepatitis a virus (hav), 206 (11.5%) hepatitis b virus (hbv), 8 (0.4%) coinfection with hbv and delta virus (hdv), 8 (0.4%) superinfection of hdv on chronic hbsag carriers and 157 (9%) non-a, non-b virus (nanb). 13 cases of cmv and 5 of ebv infections were also diagnosed. nanb viral he ... | 1987 | 3126547 |
| [hepatitis non-a, non-b: epidemiological significance in acute viral hepatitis and chronic active hepatitis of hepatological consultation]. | 157 acute viral hepatitis and 60 chronic active ones have been analyzed focusing on nanb etiology. hav was implicated in 36.3% of the hole acute viral hepatitis sample, hbv in 29.3%, and hnanbv was presumed as etiology in 31.2%, 5 patients (3.2%) had acute infection by hav, on previous one by hbv, except for epstein-barr virus, no other test for viruses were determined (cmv, hsv, etc.). male/female ratio was 1.4:1, 1.9:1, and 1.4:1 for hav, hbv and hnanbv acute hepatitis respectively; hav was th ... | 1987 | 3126619 |
| acute delta superinfection in a previously unrecognised hbsag carrier with transient loss of hbsag simulating acute non-a, non-b hepatitis. | an 18 yr old previously well male taiwanese was admitted with malaise, anorexia, and jaundice for two weeks. results of liver tests were compatible with acute hepatitis. on day 1, he was seronegative for hbsag, igm anti-hav, igm anti-hbc, igm anti-cmv, and igm ebv capsid ab, but positive for anti-delta in association with anti-hbc and anti-hbs. at follow up on day 5 hbsag converted to positive with decreasing titre of anti-hbs. on day 19, the titre of hbsag increased concomitantly with loss of a ... | 1988 | 3135251 |
| hepatitis a virus and non-a, non-b virus superinfections in hbsag chronic carriers. | clinical course, morphologic changes, immunohistochemical localization of hbv-associated markers (hbsag, hbcag), and serum hbv-dna production are described in 2 chronic hbsag carriers superinfected with hav and hepatitis non-a, non-b virus. our data suggest that the superinfections do not cause more severe disease and do not influence the clinical course of the hbsag chronic carriers. our observations indicate that a careful diagnosis of hepatocytolysis is necessary in hbv chronic infection, in ... | 1988 | 3146516 |
| fulminant viral hepatitis in kuwait. | this study describes the aetiology and clinical course of fulminant viral hepatitis in 34 patients. sixteen of 34 (47%) patients presented with serological evidence that indicated that hepatitis b virus (hbv) was the cause of fulminant hepatitis, while in 13 of 34 (38%) non-a, non-b (nanb) virus was implicated as the cause. further, in three cases (9%) and two cases (6%) the patients' serological data indicated that hepatitis a (hav) and the delta agent superinfection, respectively, were the cau ... | 1988 | 3151428 |
| spontaneous and experimental hepatitis a in old world monkeys. | virologic, serologic, biochemical, and morphological data characterizing spontaneous hepatitis a (ha) in cynomolgus macaques (macaca fascicularis) and green monkeys (cercopithecus aethiops) are reported. experimental ha was induced in macaques as a result of infection with human hepatitis a virus (hav-h). disease similar to human ha was induced in cynomolgus macaques by hav isolates from spontaneously sick rhesus (m. mulatta) and green monkeys. this experimental model of ha in macaques can be us ... | 1988 | 3193448 |
| an outbreak of foodborne hepatitis a in a factory: a possible shift in age of patients in japan. | we investigated extensively an outbreak of hepatitis a at a factory in suburban nagoya. epidemiological study indicated a foodborne outbreak by a supplier of lunches. serologically, all the employees younger than 30 years of age had been susceptible to hepatitis a virus, but the highest morbidity was observed in the 40-44 age group. the age difference in morbidity from foodborne hepatitis and susceptible populations suggests a shift in mean patient age linked to a shift in antibody prevalence to ... | 1988 | 3225097 |
| increasing age--an important adverse prognostic factor in hepatitis a virus infection. | 1988 | 3230539 | |
| [prevalence of hepatitis caused by a, b and d virus in children]. | the aim of this study was to determine the prevalence due to hepatitis a, b and d viruses infection in children. a total of 286 children from madrid area with ages ranging between 0 and 13 years were included. the sample was randomized with respect to the sex and age referring to the total population of madrid. the anti-hav was positive in 15.16% of cases, with an increasing lineal correlation with age. any marker of hbv infection was found in 6.6% and hbsag in 1.4%. there was an exponential cor ... | 1988 | 3232891 |
| influenza-like syndrome in homosexual men: a prospective diagnostic study. | in the course of a prospective study of the prevalence and incidence of infection with the human immunodeficiency virus (hiv) and risk factors for the acquired immune deficiency syndrome among 961 homosexual men, 97 initially hiv antibody seronegative men reported a febrile period lasting at least three days. in 60 of these men serological evidence for an infection was found: influenza a or b virus (17 men), hiv (14), epstein-barr virus (seven), parainfluenza virus type i, 11 or ill (five), hepa ... | 1988 | 3256668 |
| the seroepidemiology of hepatitis a virus infection in jordan. | 1988 | 3262944 | |
| emergency liver transplantation for fulminant hepatitis. | orthotopic liver transplantation was done in 17 patients with fulminant hepatitis. the cause of the liver disease was infection with hepatitis b virus, or co-infection with hepatitis b virus and hepatitis d virus, or infection with hepatitis a virus in 6 patients; drug hepatotoxicity in 5; and indeterminate in 6. grafts from incompatible blood groups, steatotic grafts, or reduced-size grafts were used in 5, 4, and 4 patients, respectively. of the 17 patients, 5 died: 2 of early liver failure due ... | 1987 | 3304049 |
| [immunology of liver diseases]. | acute hepatitis a is diagnosed by igm-anti-hav antibodies. cytotoxic immune reactions seem to play a key role in the pathogenesis of hepatitis a, which is an acute self-limited disease. - acute hepatitis b is diagnosed by igm-anti-hbc antibodies and can thus be differentiated from other hbv-associated liver diseases. the detection of hbv-dna in serum serves to differentiate between hbsag/anti-hbe positive patients, with active viral replication and progressive chronic liver disease, and hbv-dna ... | 1987 | 3313682 |
| indirect immunofluorescence application in the epidemiological study of hepatitis a. | we used iif test for seroepidemiological study on 531 sera divided in age-groups obtained from apparently healthy subjects of rome. our results confirm the endemicity of hav (hepatitis a virus) infection in rome with a prevalence of more than 50%. the application of the anti-hav iif (indirect immunofluorescence) test to a large number of sera demonstrated its usefulness as a quantitative and qualitative test in the epidemiological field. | 1987 | 3327512 |
| sexually transmitted diseases, antibodies to human immunodeficiency virus, and subsequent development of acquired immunodeficiency syndrome. visitors of homosexual sauna clubs in copenhagen: 1982-1983. | sera from 260 men from denmark and elsewhere attending two copenhagen sauna clubs for homosexual men during nine months of 1982-1983 were investigated for markers for syphilis, hepatitis a and b, and human immunodeficiency virus (hiv). five per cent (12 men) had active syphilis, and another 35% (92) had a history of and/or serologic markers for syphilis. ninety-four men (36%) were positive for antibodies to hepatitis a virus, ten (4%) were positive for hepatitis b surface antigen (hbsag), and 15 ... | 1988 | 3358236 |
| reactivation of hepatitis b virus in anti-hbe-positive chronic active type b hepatitis: molecular and immunohistochemical studies. | the causes of acute clinical exacerbations, and the role of reactivation of hepatitis b virus (hbv) in 16 non-cirrhotic patients with chronic active type b hepatitis (cah-b) negative for serum hepatitis b e antigen (hbeag) but positive for anti-hbe, were studied by molecular hybridization and immunohistochemical methods. igm antibody to hepatitis a virus (anti-hav igm) and antibody to delta agent (anti-delta) were negative in all. hbeag reappeared transiently in only two patients. serum hepatiti ... | 1988 | 3360397 |
| prevalence of hepatitis a virus infection in spain. | 1988 | 3363302 | |
| a prospective study of viral hepatitis a and the question of chronicity. | in a prospective study, the author followed up the course of hepatitis a (ha) in 451 patients, predominantly schoolchildren, who were treated in the years 1982-1985 in the department for infectious diseases of the celje municipal hospital. ha was identified by the present of hepatitis a virus igm class (anti-hav-iggm) in the serum, and in one-third of the patients (38.6%) also with serological proof of the presence of the hepatitis a virus antigen (haag) in the feces. other liver diseases which ... | 1988 | 3371849 |
| [hemodialysis with a high permeability membrane in the treatment of encephalopathy of fulminant hepatitis]. | twenty-nine patients with fulminant hepatic failure and at least grade iii encephalopathy were treated by haemodialysis with a polyacrylonitrile membrane. aetiology was toxic in five patients, viral in eleven (2 due to hepatitis a virus and 9 presumed due to hepatitis b virus), not found in thirteen. each patient was dialysed for 4 h every day, until he regained consciousness or died. conscious level was improved after dialysis in 59% of patients. thirteen patients survived (44.8%) :4 toxic hepa ... | 1987 | 3434887 |
| [the family bath: a risk of contamination by the hepatitis a virus]. | 1987 | 3442466 | |
| the prevalence of antibody to hepatitis a virus in singapore. | 1987 | 3452400 | |
| a seroepidemiologic study of hepatitis a virus infections: statistical analysis of two independent cross-sectional surveys in okinawa, japan. | to investigate the endemic situation of hepatitis a virus infection in the past in okinawa, japan, the authors analyzed two sets of cross-sectional data on age-specific prevalence of antibody to hepatitis a virus (anti-hav) obtained in 1968-1973 and 1980-1981 by fitting a catalytic model. for these two sets of data, the asymptotic level of infectious force of hepatitis a virus, namely lambda infinity, was estimated as 0.121 and 0.149, the maximum slope of the time-dependent force of hepatitis a ... | 1987 | 3496004 |
| evidence of hepatitis virus infection among australian prisoners of war during world war ii. | a sample of australian male veterans of world war ii was surveyed after 40 years. one hundred and seventy veterans had been held by the japanese as prisoners of war and 172 veterans had served in southeast asia but had not been taken captive (non-prisoners of war). a medical history was obtained and a physical examination undertaken. blood was drawn and analysed for standard liver biochemistry and serological markers of hepatitis a and b virus (hav, hbv) infections. the prevalence of immunoglobu ... | 1987 | 3499558 |
| hepatitis a, b, and delta infection in ethiopia: a serologic survey with demographic data. | a total of 500 individuals from five different regions of ethiopia were studied. demographic and clinical data were recorded and serologic tests were carried out to detect antigen and antibody markers of hepatitis b virus, hepatitis a virus, and the delta agent. data on the economic status, number of rooms per household, number of persons per household, type of water supply, and mode of excreta disposal revealed that the majority of the population surveyed lived with economic hardship, overcrowd ... | 1986 | 3511678 |
| a seroepidemiologic study of hepatitis a in malaysia. | sera from 494 non-icteric patients admitted with illnesses other than overt hepatitis into the various hospitals in rural and urban malaysia were tested for igg antibody to hepatitis a virus. the overall antibody prevalence rate was 67.0% with rates increasing steadily from childhood 10 years old and under (39.4%) to middle-age and above (96.0%). no significant differences were noted between males (68.4%) and females (65.3%). the highest rate was in the indians (80.6%), the lowest in the chinese ... | 1986 | 3538434 |
| demonstration of calicivirus in human faeces by immunosorbent and immunogold-labelling electron microscopy methods. | immunosorbent electron microscopy (isem) and immuno-gold staining (igs) electron microscopy methods have been applied to human faeces, shown by direct electron microscopy (em) to contain calicivirus. caliciviruses were successfully trapped on grids coated with positive rabbit or human antisera against calicivirus, but not with negative sera. caliciviruses were specifically labelled with gold particles, when treated with positive rabbit or human antisera against calicivirus followed by protein a- ... | 1986 | 3539960 |
| correlation between hepatic hepatitis b core antigen and serum hepatitis b virus-dna levels in patients with chronic hepatitis b virus infections in taiwan. | paired liver biopsy specimens and serum samples from 76 patients with chronic hepatitis b virus (hbv) infection were taken for staining of hepatitis b core antigen (hbcag) by immunoperoxidase and testing of hbv-dna by a spot hybridization technique, respectively. thirty-two tissue specimens showed positive staining for hbcag in their hepatocytes. the two patients with diffuse hbcag expression in liver tissue also had high serum concentrations of hbv-dna (greater than 10 pg/10 microl). among 30 p ... | 1987 | 3545139 |
| viral antibodies in agricultural populations exposed to aerosols from wastewater irrigation during a viral disease outbreak. | the presence of antibodies to eight enteroviruses (echovirus types 4, 7, and 9, coxsackievirus types a9, b1, b3, and b4, and hepatitis a virus) and varicella-zoster virus was determined during a two-year period, 1980-1981, in paired blood samples of 777 persons in selected agricultural communities (kibbutzim) in israel. these communities were divided into several categories on the basis of wastewater utilization for sprinkler irrigation and/or fish ponds. among the nine viral antibodies studied, ... | 1987 | 3565365 |
| natural history of acute hepatitis b surface antigen-positive hepatitis in greek adults. | we prospectively followed up 821 adults with acute viral hepatitis hospitalized at the athens hospital for infectious diseases between may 1981 and may 1983. radioimmunoassays for the detection of serologic markers of hepatitis a virus, hepatitis b virus, and hepatitis delta virus, and molecular hybridization techniques for the detection of serum hepatitis b virus deoxyribonucleic acid and hepatitis delta virus ribonucleic acid were used. based on the results of an enzyme immunoassay for the det ... | 1987 | 3569758 |
| persistence of a positive test for igm antibodies to hepatitis a virus in late convalescent sera. | we had the opportunity to carry out a long-term follow up of 15 patients with viral hepatitis type a. the serum igm response to hepatitis a virus (hav) was investigated with a commercially available kit (havab-m). igm antibodies were detected in all specimens collected during the acute phase of the disease and during early convalescence (first 3 months). however, there was a clear decrease in the "sample-to-cutoff" ratio (s/co ratio) after the first 2 months. serum samples were available from si ... | 1987 | 3583701 |
| induced oral infection of the owl monkey (aotus trivirgatus) with hepatitis a virus. | several species of nonhuman primates have served as animal models for hepatitis a virus (hav) infection and disease. this study was to determine the suitability of aotus trivirgatus as an orally induced model for hav infection and to reconfirm the owl monkey's susceptibility to the intravenous route of inoculation. animals were inoculated, either orally or intravenously, with varying concentrations of pa-33 strain of hav. serum enzymes alt, ast and ggtp levels were monitored and liver biopsies p ... | 1987 | 3586603 |
| infection with hepatitis a and b viruses in french volunteers working in tropical africa. | the risks of developing hepatitis a and b virus infections were studied in 233 french volunteers working for 18 to 35 months in the field in west and central africa. during their stay in africa, the seroconversion rates to antibody to hepatitis a virus of the immunoglobulin g (igg) class and hepatitis b marker(s) were 48.1% and 10.5%, respectively; 21.5% of the volunteers developed jaundice, and 78.0% of the jaundice cases were associated with hepatitis a seroconversion, 14.0% with hepatitis b s ... | 1987 | 3591787 |
| relapsing hepatitis associated with hepatitis a virus in a pediatric population. | 1987 | 3663340 | |
| viral hepatitis and pregnancy in kuwait. | the frequency and severity of viral hepatitis among pregnant and non-pregnant women in kuwait was studied from 1980 to 1984. 542 female hepatitis patients were investigated, of whom 52 (9.6%) were pregnant. 35 of the 52 (67.3%) cases of viral hepatitis in pregnancy were due to hepatitis b virus while 11 of 52 (21.2%) and 6 of 52 (11.5%) had acute hepatitis non-a, non-b (nanb) and hepatitis a virus infections, respectively. the frequency and severity of viral hepatitis among the pregnant women wa ... | 1987 | 3686634 |
| a modified, solid phase radioimmunoassay for the differential diagnosis of acute and convalescent phases of hepatitis a infection. | the commercial assays for diagnosing the presence of hepatitis a antibodies (havab; abbott laboratories, north chicago, il) or the presence of igm class anti-hepatitis a virus antibodies (havab-m; abbott) do not provide precise information as to the timing of the acute infection. igm class antibodies are detected as late as six months after the acute infection. in this study the authors describe a modified havab test that inactivates the igm class antibodies. it thus measures the proportion of i ... | 1987 | 3687845 |
| recombinant alpha 2c-interferon therapy in fulminant viral hepatitis. | recombinant alpha 2c-interferon was administered to 12 consecutive patients with fulminant viral hepatitis. the disease was caused by coinfection by hbv and hdv in seven patients, by hdv superinfection of a chronic hbv carrier in two, by hbv alone in two and by hav in one. eight patients were drug addicts. interferon administration was initiated shortly after the onset of hepatic encephalopathy and no patient was in grade iv coma at the beginning of therapy. ten patients died and only two surviv ... | 1987 | 3693864 |
| [glomerular nephropathy with mesangial proliferation and acute hepatitis a virus infection. 2 cases]. | 1986 | 3706993 | |
| clinical, serologic, and epidemiologic aspects of hepatitis a virus infection. | 1986 | 3715483 | |
| appearance and persistence of hepatitis a igm antibody in acute clinical hepatitis a observed in an outbreak. | 143 patients with acute hepatitis a observed during a common source outbreak were tested for igm class antibody to hepatitis a virus (igm anti-hav) by commercially available solid phase radioimmunoassays. all patients were igm anti-hav positive though six of them were initially negative when tested within three days after the onset of symptoms. the levels of igm anti-hav peaked two to four weeks after onset, and declined gradually thereafter. the probability of igm anti-hav positivity was 25% at ... | 1986 | 3759243 |
| acute pancreatitis in hepatitis a infection. | hepatitis viruses are an uncommon cause of acute pancreatitis. we present the case of a boy with acute pancreatitis complicating viral hepatitis with satisfactory recovery. the finding of igm-anti hav antibodies implicates hepatitis a virus as the cause. | 1986 | 3763554 |
| diagnostic usefulness of anti-hbc-igm and anti-hd antibodies in acute viral hepatitis. | to evaluate diagnostic improvement achieved with the determination of antibody to hepatitis core antigen of igm type (anti-hbc-igm) and antibody to delta antigen (anti-hd) in acute type b hepatitis, 155 patients (of whom 100 were drug addicts) were studied, using these markers in association with the classical markers of viral hepatitis (anti-hbc, anti-hbs, anti-hav-igm and anti-cytomegalovirus antibodies). with classical diagnostic criteria, 121 patients would have been diagnosed as having b he ... | 1986 | 3803810 |
| a case of acute renal failure associated with type a acute hepatitis responds dramatically to plasmapheresis. | a case of acute renal failure (arf) associated with type a acute hepatitis followed by a dramatic response to plasmapheresis is described. a female patient was transferred to our hospital with a diagnosis of arf associated with acute hepatitis. since radioimmunoassay for igm antibody to hepatitis a virus showed a positive reaction, recent infection with hepatitis a virus was suspected. hemodialysis immediately performed after admission was not effective. plasmapheresis was started on the 5th hos ... | 1986 | 3810690 |
| [seroepidemiology of hepatitis a virus infection in communities of the southern border of the state of chiapas]. | 1986 | 3814321 | |
| [hepatitis a and b virus infections in refuse workers in asti]. | the authors have examined hepatitis a and b virus infection risk in 93 dustmen and sewer workers. it has non been found a risk correlated with employment, though for some of them, with peculiar functions, the hbv and/or hav serological markers prevalence rates were higher than in the remaining of the studied population. | 1985 | 3836919 |
| frequency of illness associated with epidemic hepatitis a virus infections in adults. | hepatitis a virus infection is often described as mild or asymptomatic, particularly in children. the failure of most adults who are found to be immune to remember symptoms of an illness suggestive of hepatitis a virus supports this belief. in 1982, two large outbreaks occurred in well documented populations of military personnel. these outbreaks were each extensively studied epidemiologically and serologically. it was found that 28/29 (96.6%) hepatitis a infections recognized prior to immune se ... | 1985 | 3860002 |
| [hepatitis a antibodies in young hemophiliacs]. | the proof of antibodies against the hepatitis a-virus (anti-hav) is a frequent finding in substituted haemophiliacs. anti-hav is apparently not the expression of an actively acquired immunity, but might have been transmitted above all passively by means of the plasma preparations. among 68 haemophilic children and adolescents anti-hav was proved 22 times, in 33 boys of about the same age with undisturbed blood coagulation only twice. of 40 cryoprecipitate 22 were anti-hav-positive. thus as a sid ... | 1985 | 3873754 |
| hepatocyte hepatitis b surface antigen. diagnostic evaluation of patients with clinically acute hepatitis b surface antigen-positive hepatitis. | patients who were diagnosed as having acute hepatitis b by conventional criteria were reevaluated by a correlative study of tissue hepatitis b surface antigen (hbsag) and serologic tests for anti-hepatitis a virus, igm, and/or anti-hepatitis b core antigen (anti-hbc) igm. the results demonstrated that the diagnosis of acute hepatitis b in an endemic area was complicated by superinfection or reactivation of unrecognized hepatitis b carriers or chronic hepatitis b patients simulating acute hepatit ... | 1985 | 3885902 |
| serological hepatitis a virus infections and ratio of clinical to serological infections in a controlled trial of pre-exposure prophylaxis with immune serum globulin. | seroconversion to hepatitis a virus was studied in a sub sample of 802 israeli military recruits (611 men and 191 women) who were taking part in a randomised controlled trial of pre-exposure immune serum globulin (isg) for the prevention of viral hepatitis. on intake into the service 35% of the men and 47% of the women were negative to hepatitis. a virus antibody (anti-hav). after three years 7 of 71 men (9.9%) who had not received pre-exposure isg had become positive to anti-hav compared to 2 o ... | 1985 | 3891900 |
| enzyme immunoassay for detection of total and igm-specific antibodies to hepatitis a virus and its clinical application. | antibody to hepatitis a virus (anti-hav) and igm class antibody to hav (igm anti-hav) in sera from 73 patients with hepatitis a and from 550 normal subjects were measured by enzyme immunoassay (eia) and the results were compared with those of radioimmunoassay (ria). since ria has the disadvantage of requiring radioisotopes and special equipment, the clinical applicability of eia and possible methodological problems were evaluated. the eia for anti-hav showed an excellent correlation with ria, in ... | 1985 | 3896908 |
| [acute cholecystitis disclosing a virus hepatitis]. | three children presenting with hav hepatitis had an initial clinical onset suggestive of acute cholecystitis (pain and guarding in the right hypochondrium, fever and delayed jaundice) associated with important ultrasonographic abnormalities, also very suggestive of acute cholecystitis: bladder wall thickness greater than 10 mm (3 cases), the presence of 2 or 3 layers of different echogenicities (3 cases), presence of an ultrasonographic murphy's sign (one case), contents of the gallbladder echog ... | 1985 | 3909976 |
| the agents of non-a, non-b viral hepatitis. | recent studies have provided physicochemical and electron microscopic evidence for the existence of two distinct agents of posttransfusion non-a, non-b (nanb) hepatitis. one of these agents is chloroform-resistant and is not associated with the formation of unique ultrastructural structures in infected liver. the other agent is chcl3-sensitive, induces the formation of characteristic hepatocyte cytoplasmic tubules, and interferes with concurrent hav or hbv infection in experimentally inoculated ... | 1985 | 3923011 |
| human lymphocyte responses to hepatitis a virus-infected cells: interferon production and lysis of infected cells. | peripheral blood mononuclear cells (pbmc) from nonimmune healthy donors who did not have antibody to hepatitis a virus lysed hepatitis a virus-infected bs-c-1 cells to a greater degree than uninfected bs-c-1 cells. the predominant effector cells were contained in the nonadherent peripheral blood lymphocyte (pbl) fraction, although some lytic activity was associated with adherent cells. characterization of the pbl with monoclonal antibodies showed that the responsible effector lymphocytes were co ... | 1985 | 3926897 |
| acute viral hepatitis superimposed on alcoholic liver cirrhosis: clinical and histopathologic features. | of 20 patients with alcoholic liver cirrhosis and a superimposed episode of acute viral hepatitis, 12 developed hepatic encephalopathy or ascites or both. four died of hepatic failure. seventeen patients had received blood transfusions within 6 months before the acute hepatitic episode. two patients were hbsag-positive; the other 18 were presumptively diagnosed as having non-a, non-b hepatitis. however, hepatitis a virus infection was excluded in only three of the 18 patients. histologic examina ... | 1985 | 3935897 |
| viral hepatitis among danish oral surgeons. | the aim of the study was to investigate the prevalence of previous clinical hepatitis b virus (hbv) infection and the prevalence of hbv markers in danish oral surgeons, to estimate the annual hbv infection rate, and to assess whether the use of hepatitis b vaccine is to be recommended for this group. the total study population comprised 40 individuals occupied with oral surgery. a questionnaire and a request for a blood sample were sent to all dentists employed at the danish hospitals and the de ... | 1985 | 3936792 |
| [epidemiologico-clinical considerations on a case file of acute hepatitis observed 1980-1983]. | between january 1980 and december 1983, 332 consecutive cases of acute hepatitis were observed in adult patients admitted to the department of infectious disease and gastroenterology of siena. sex and age of the patients, the presence of jaundice, the maximum value of the serum-glutamate-pyruvate-transaminase (sgpt) were considered. serum specimens were tested for hepatitis b surface antigen (hbsag), antibody against hepatitis b core antigen (anti-hbc) of the igm class, antibody against hepatiti ... | 1985 | 3938288 |
| a biphasic illness associated with acute hepatitis a virus infection. | four patients are described with serologically proven hepatitis a (hav) infection. in each patient there was a bimodal course to the illness--clinically and biochemically--with complete remission between the two phases of the illness. other possible causes except nanb for a second hepatitic illness were excluded. | 1986 | 3950361 |
| viral hepatitis risk in urban emergency medical services personnel. | houston has large groups of people known to be at high risk for hepatitis b virus (hbv) infection. emergency medical services (ems) personnel are continuously exposed to blood from these high-risk individuals. we sought to determine the prevalence of hbv infection in the city's ems personnel. of the 350 houston firefighters assigned to ems, 344 were surveyed by questionnaire and a blood specimen was obtained. each sample was assayed by radio-immunoassay or enzyme-linked immunoassay for hepatitis ... | 1986 | 3954182 |
| a waterborne outbreak of hepatitis a in meade county, kentucky. | in november 1982, meade county, kentucky health officials noted a sudden increase in the incidence of hepatitis a. using a standardized interview of 73 cases (68 serologically confirmed), and 85 controls (all negative for antibody to hepatitis a virus), the most important risk factor identified was household use of untreated water from a single spring. a dose-response relationship was found for consumption of unboiled spring water. water samples taken from the spring during the outbreak were con ... | 1985 | 3966622 |
| viral hepatitis in colombia: a study of the "hepatitis of the sierra nevada de santa marta". | the prevalences of hepatitis b virus (hbv), hepatitis delta virus and hepatitis a virus infections were studied in two regions of colombia. in bogota, 10 of 53 patients with acute hepatitis were hbsag positive and three of these were hepatitis d antigen positive. hepatitis a virus was the major cause of acute hepatitis in this group. in 366 healthy controls from bogota, 1.6% were hbsag positive and 7.1% had at least one marker of hbv infection. in northern colombia, individuals from three villag ... | 1985 | 3979961 |
| incidence of hepatitis a virus (hav) infection in rural liberia. | to provide background for future hepatitis a vaccine trials, sera were collected from 0- to 4-year-old liberian infants and their mothers on two occasions an average of 14.75 months apart and tested for antibody to hepatitis a virus (anti-hav). the prevalence of anti-hav rose from 2.5% in infants 0-6 months of age to 70% in children 3-4 years of age and did not differ between male and female infants. the annual incidence of new infections was slightly lower in the first year of life (35%) than i ... | 1985 | 3981150 |
| prevalence of hepatitis virus and some arbovirus infections in kavango, northern swa/namibia. | a survey of the frequency of hepatitis b markers in 258 subjects from kavango, northern south west africa/namibia, was undertaken during february - may 1983. the hepatitis b surface antigen and hepatitis b e antigen carrier rates were 13,6% and 2,7% respectively. only 1,9% of the subjects were negative for all the markers tested, indicating that infection had been present at some stage in 98,1% of the sample. no known transmission method of the virus seems to fit this high exposure rate. the pos ... | 1985 | 3983734 |
| reactivation of chronic type b hepatitis presenting as acute viral hepatitis. | three asymptomatic chronic carriers of hepatitis b surface antigen, who had normal serum aminotransferase levels and no detectable hepatitis b e antigen in serum, developed icteric, symptomatic acute hepatitis. serologic evidence of acute infection with hepatitis a virus, delta hepatitis virus, cytomegalovirus, or epstein-barr virus was absent. however, hepatitis b virus dna and dna polymerase activity, which were not detectable before the exacerbation, appeared in the serum of all three patient ... | 1985 | 3994187 |
| clinical and serological events accompanying changes in hepatitis b viral replication: case reports. | we measured serum markers of hepatitis b virus replication in two hbsag-, hbeag-positive hepatitis b carriers with chronic active hepatitis and cirrhosis. the first of these patients was hbsag-, hbeag-, hbv dna- and hbv dna polymerase-positive initially and spontaneously lost hbv dna polymerase and hbv dna. during the hbeag-positive, dna polymerase-negative "window phase", an increase in viral replication, characterized by the reappearance of hbv dna and hbv dna polymerase occurred, together wit ... | 1985 | 3999935 |
| how often does chronic liver disease follow acute hepatitis b in adults? | the risk of developing the chronic hepatitis b surface antigen (hbsag) carrier state after primary acute hepatitis b virus infection was examined in a prospective study of adults with acute icteric (clinically apparent) viral hepatitis. enzyme immunoassay for igm antibody to hepatitis b core antigen (igm anti-hbc) was positive in 176 (93.1%) and negative in 13 (6.9%) of 189 patients positive for hbsag and negative for igm antibody to hepatitis a virus. the former were considered to be acute hepa ... | 1985 | 4044044 |
| [detection of inapparent forms of hepatitis in foci of the infection by using sensitive methods of specific diagnosis]. | the use of specific sensitive methods for demonstration of hepatitis a markers has made it possible to detect 6 children with inapparent form of the disease among 86 subjects present in the focus of infection. specific hav antibody of the m class were detected in 100% of them. by radioimmunoassay, hepatitis a virus antigen (hav-ag) was detected in fecal extracts in 1 case only. liver biopsy from 1 patient with inapparent disease showed typical morphological signs of acute hepatitis, and hav-ag w ... | 1985 | 4049845 |
| prevalence of immunologic markers of hepatitis a and b infection in hospital personnel in miyazaki prefecture, japan. | between 1980 and 1983, a total of 1,883 serum samples from employees of four prefectural hospitals in miyazaki prefecture, japan were surveyed for antibody to hepatitis a virus (anti-hav) and for the following hepatitis b virus markers: hepatitis b surface antigen (hbsag), antibody to hbsag (anti-hbs), and antibody to hepatitis b core antigen (anti-hbc). overall prevalences were 36.9% for anti-hav, 3.4% for hbsag, 23.3% for anti-hbs, and 36.6% for anti-hbc. in the control group of 233 healthy pe ... | 1985 | 4061446 |
| acute exacerbation in hepatitis b e antigen positive chronic type b hepatitis. a clinicopathological study. | during a 6-year (mean 24.5 months) follow-up study of 237 hbeag-positive patients with biopsy-verified chronic type b hepatitis, 199 episodes of acute exacerbation (sgpt greater than 300 iu/l) were observed in 148 patients. the clinical and laboratory findings of these acute exacerbations were less severe than classic acute viral hepatitis (p less than 0.001) but with remarkable overlapping. the main histological changes of acute exacerbations were those of lobular hepatitis, even with bridging ... | 1985 | 4067255 |
| papular acrodermatitis of childhood associated with hepatitis a virus infection. | a 2-year-old girl developed an erythematous papular eruption on her face and extremities a week after an epidemic of hepatitis a had occurred in her school. clinical and laboratory signs of acute hepatitis, together with serologic verification, confirmed hepatitis a infection. that diagnosis should be considered in the etiology of papular acrodermatitis of childhood. | 1985 | 4070084 |
| [diagnostic significance of the detection of hepatitis b virus dna in acute and chronic hepatitis]. | 1065 sera from patients with acute and chronic hepatitis-b-virus-(hbv-) infections, double infections (hbv, hav, nona-nonb, delta-ag) as well as patients with hbs-ag-negative hepatitis (hav, nona-nonb) and healthy subjects were investigated for the presence of hepatitis-b-virus-dna using molecular hybridisation. the sensitivity of the method was 0.1 pg hbv-dna/100 microliters. hbv-dna could be detected in 62% of cases of hbs-ag-positive sera with hbe-ag, in 8.9% with anti-hbe and in 11% of e-mar ... | 1985 | 4075993 |
| incidence and significance of hepatitis b and a virus serologic markers in greek cirrhotic patients. | the incidence of serological markers of hepatitis b and a virus infection was studied by radioimmunoassay in 89 greek cirrhotic patients. controls consisted of 90 patients without liver disease. hbsag was detected in 62 (69.5%) patients, anti-hbs in 35 (39.3%), anti-hbc in 60 (67.4%), hbeag in 13 (14.6%), anti-hbe in 58 (65.1%), and the anti-hav in 86 (96.6%). the corresponding figures for the control group were: hbsag 4 (4.5%), anti-hbs 34 (37.7%), anti-hbc 41 (45.5%), hbeag 3 (3.3%), anti-hbe ... | 1985 | 4076727 |
| serum binding activity for human albumin polymers in acute and chronic virus hepatitis. | we considered the serum binding activity for human albumin polymerized with glutaraldehyde in 346 serum samples of 205 subjects with acute and chronic type a, b and non-a, non-b virus hepatitis. we showed that the binding activity for phsa in the control groups did not have a titer higher than 2(-6). all sera from patients with hav and hbv acute infection showed a high binding titer that returned to below the threshold in the former after the peak of hepatocytolysis, and in the latter after the ... | 1985 | 4077012 |
| double infections with hepatitis a and b viruses. | ten (2.8%) asymptomatic carriers of hbsag and four (1.1%) patients with acute hepatitis b virus (hbv) infection were detected among 356 adults with acute viral hepatitis a (hav) consecutively admitted to the athens hospital for infectious diseases from may 1981 to march 1984. these patients did not differ in clinical, epidemiologic (except in age), biochemical or serologic characteristics from patients acutely infected with hav alone. transient suppression of the hbv replication and disappearanc ... | 1985 | 4088008 |
| a new subtype of type a influenzavirus isolated from turkeys. | a new subtype of avian influenzavirus a was isolated in january 1967 from an epizootic in a turkey hatchery in ontario, canada. the disease was fatal in 65 of 2 500 hens involved. virus was isolated from lung and trachea tissue of three dead turkeys. sera from convalescent birds contained antibody against the viruses isolated from the outbreak but not against other known type a avian influenzaviruses, newcastle disease virus, myxovirus yucaipa, or mycoplasma gallisepticum.the strain designated a ... | 1972 | 4541004 |
| etiologic relationship of marmoset-propagated cr326 hepatitis a virus to hepatitis in man. | 1973 | 4632938 | |
| [hepatitis--a virus induced autoimmune disease]. | 1973 | 4790317 | |
| letter: hepatitis a virus-like particles. | 1974 | 4816861 | |
| buoyant density of the hepatitis a virus-like particle in cesium chloride. | we recently visualized by immune electron microscopy a virus-like particle in the stools of patients with hepatitis a. the particle measured approximately 27 nm in diameter and morphologically resembled a picornavirus or parvovirus. to further characterize this particle, we have determined its buoyant density in cesium chloride (cscl) by ultracentrifugation. hepatitis a particles from three positive stool specimens were isopycnically banded in separate experiments, and the gradient fractions wer ... | 1974 | 4833615 |
| [demonstration and occurrence of igm-type hepatitis a viral antibodies]. | hepatitis-a antibody of the igm class can be demonstrated in serum by radio-immunoassay quickly, relatively cheaply and simply. the diagnosis of fresh or recent hepatitis-a virus infection can be made from a single serum sample in a single test. epidemiological analysis of the positive findings obtained in 1981 gave the following results: 1. hepatitis-a is, in germany, largely a disease of young adults, with an average age of 24 years. but cases still occurred above the age of 50.2. among foreig ... | 1984 | 6086261 |
| immunoprophylaxis of hepatitis a of the children by immune serum globulin. | an outbreak of hepatitis a occurred in kyoto. immune serum globulin was administered prophylactically to children who had not yet developed the disease. however 52 children in succession contracted hepatitis a. late injections of immune serum globulin had no effect on the clinical course. middle injections suppressed only jaundice. early or preexposure injection suppressed the disease remarkably. all who had overt hepatitis a seroconverted to positive antibody to hepatitis a virus. in inapparent ... | 1984 | 6086439 |
| primary isolation and serial passage of hepatitis a virus strains in primate cell cultures. | although several primate cell types have been reported to support replication of hepatitis a virus, optimal conditions for the isolation and production of quantities of virus have not been defined. we therefore examined seven different primate cell types for their ability to support replication of primate-passaged and wild-type virus as reflected by intracytoplasmic accumulation of viral antigen (direct immunofluorescence and radioimmunoassay) and propagation of cell culture-adapted virus. of th ... | 1984 | 6086708 |
| hepatitis a, b, and non-a, non-b in danish hospital nursing staff. | a stratified age matched sample of 564 general hospital nurses, assistant nurses, and porters was studied for antibody to hepatitis a virus (anti-hav), hepatitis b surface antigen (hbsag), and antibody to hepatitis b surface antigen (anti-hbs), and these data were compared with serum aspartate aminotransferase (ast) and identified episodes of hepatitis. the overall prevalence of anti-hbs was increased twofold compared with blood donors, while no evidence of increased exposure to hepatitis a viru ... | 1984 | 6086725 |
| monoclonal antibodies to hepatitis a virus. | this paper describes the development of monoclonal antibodies generated against hepatitis a virus (hav). monoclonal antibodies (mcabs) from two murine hybridoma cell lines were found to bind to an epitope recognized in the sera of patients recovering from infection with hav. ascites fluids containing mcabs from one hybridoma (h1 c19) inhibited a maximum of 70% of the 125i-labeled polyclonal human anti-hav from binding to hav-antigen in a competitive radioimmunoassay, indicating that the mcab rec ... | 1984 | 6086829 |
| [effect of the content of hepatitis a antibodies in immunoglobulin preparations on the effectiveness of the immunoglobulin prophylaxis of hepatitis a]. | the results of a strictly controlled experiment showed that prevention of hepatitis a by the injection of immunoglobulin with hepatitis a virus (hav) antibody titer 1:10000 was 3 times as effective as that achieved with immunoglobulin containing hav antibodies in titer 1:2500. it is recommended to determine the level of specific hav antibodies in immunoglobulins and to use immunoglobulins with a high level of hav antibodies for prevention of hepatitis a. | 1984 | 6087581 |
| interference between human hepatitis a virus and an attenuated apathogenic avian virus. | the effect of an attenuated apathogenic avian bursa virus on the course of human hepatitis a viral infection was studied in marmoset monkeys. the monkeys were infected with human hepatitis a virus, then superinfected with avian bursa virus one and three weeks after initial inoculation with human hepatitis a virus. the superinfected monkeys did not show the characteristic serum glutamic pyruvic transaminase (sgpt) elevation. also their liver biopsies showed no pathologic changes. the virus contro ... | 1984 | 6087596 |
| transmission of hepatitis a by transfusion of blood products. | the transmission of hepatitis a by blood products has been thought to occur rarely or not at all. by measuring igm antibody to hepatitis a virus, we diagnosed a case of hepatitis a transmitted by the transfusion of a unit of fresh frozen plasma. since the commercial availability of methods for measuring igm antibody to hepatitis a, four other well-defined cases of hepatitis a transmitted by blood products have been reported in the literature. we detail our case and the natural history and import ... | 1984 | 6087755 |
| virus-binding activity of fibronectin: masking of hepatitis a virus. | human plasma fibronectin interacts with viruses. when fibronectin-containing human sera negative for antibodies to hepatitis a virus (hav) were added to suspensions of hav, radioimmunological detection of hav was reduced. this masking effect seemed to depend on the fibronectin concentration of the sera: plasma fibronectin purified by cryoprecipitation and affinity chromatography showed a masking effect on purified hav which was dependent on the concentrations of fibronectin and hav. fibronectin ... | 1984 | 6088567 |
| hepatitis a-virus in cell culture. v. neutralizing antibodies against hepatitis a-virus. | a test system for the detection of neutralizing antibodies against hepatitis a-virus (anti-hav-nt) is presented. the anti-hav-nt assay is performed with frhk-4/r cells and the hepatitis a virus (hav) strain gbm/frhk-4/r which has been adapted to these cells. non-neutralized hav is demonstrated 14 days after infection of frhk-4/r cells using a radio-immunoassay for detecting newly grown hav. the influence of differing amounts of hav on the anti-hav-nt titre and the effect of variations in incubat ... | 1984 | 6088963 |
| prevalence of markers of hepatotrophic viruses in alcoholics with symptomatic liver cirrhosis or pancreatitis. | the reason why similar amounts of alcohol consumption cause different types of organ damage in alcoholics is obscure. recent studies indicate that hepatitis b virus infection may influence the development of liver cirrhosis in alcoholics. we investigated the prevalence of markers of viruses known to cause hepatitis (hav, hbv, ebv, cmv) in two groups of patients, one with alcoholic pancreatitis without known liver cirrhosis and one with alcoholic liver cirrhosis without known pancreatitis. we fou ... | 1984 | 6089303 |
| translation in vitro of hepatitis a virus rna. | rna extracted from highly purified hepatitis a virus (hav) particles was translated in an rna-dependent, cell-free reticulocyte lysate system, and the products were analyzed by sds-polyacrylamide gel electrophoresis and compared with proteins translated from rna of poliovirus. the efficiency of translation in vitro of hav rna was comparable to that of poliovirus rna. processing of the putative precursor molecules of hav proteins, studied in pulse-chase experiments, was impaired when compared wit ... | 1984 | 6089414 |
| epidemiology of hepatitis a and b in the shanghai area: prevalence of serum markers. | different population groups from the shanghai area were surveyed by radioimmunoassay for serologic markers of previous infections with hepatitis a virus and hepatitis b virus. there were no significant differences in the prevalence of antibodies to hepatitis a virus (anti-hav) in males and females, or in persons living in rural or urban areas. the prevalence of anti-hav showed a biphasic increase with age, approaching 100% above age 50 years whereas the geometric mean titers declined. the rate o ... | 1984 | 6089547 |
| [radioimmunological survey of serological markers of viral hepatitis]. | 230 serum samples of hbsag carriers have been investigated for the presence of the combination hbeag/anti-hbe as an index infectivity: an infectivity titre of 5,65% has been found for hbeag and a positivity titre of 83,04% for anti-hbe antibody. in the institutionalized patients of an isolated community the positive titre of hbeag resulted 28,57% whilst in the relevant health care staff the positivity titre was the same as detected for the carriers mentioned above. in a episode of viral hepatiti ... | 1983 | 6090251 |
| levels of neutralizing and binding antibodies to hepatitis-a virus after onset of icterus: a comparison. | 1984 | 6090544 | |
| hepatitis viruses in southern taiwan--mass survey of 2985 inhabitants. | a survey of 2985 apparently healthy taiwanese in southern taiwan revealed a high prevalence (18.2%) of hepatitis b surface antigen (hbsag). it was significantly higher in males (22.3%) than in females (13.6%), but no correlation with family origin, socioeconomic status or residence was established. about one-third of the breeding female hbsag carriers were hbeag-positive, and these may be an important source in the spread of hbv. subtyping of hbsag in 63 subjects showed adw to be dominant in thi ... | 1984 | 6092191 |
| [viral hepatitis a and b in anthropoid apes of the moscow zoo]. | the rate of occurrence of hepatitis a and b virus specific markers in anthropoid apes of the moscow zoo (3 chimpanzees, 3 gorillas, 8 orang-outangs) was studied. long-term persistence of hbs-antigen in orang-outang accompanied by the presence of hbe-antigen and anti-hbs was demonstrated. the presence of anti-hbs in gorillas and orang-outangs was recorded. antibodies to hepatitis a virus were found in all the animal species examined. cases of acute virus hepatitis a in orang-outangs are described ... | 1984 | 6093384 |
| the changing epidemiologic pattern of hepatitis a infection in urban greece. | the point prevalence of antibody to hepatitis a virus (anti-hav) in a sample of 1,113 healthy greek children and adolescents 0-19 years old was estimated by radioimmunoassay. the overall anti-hav prevalence was 8.7%; it increased from almost zero among children less than four years of age to 16.3% in adolescents 15-19 years. anti-hav prevalence was independent of sex; it was lower among children born in athens than among those born in other parts of the country, and it was higher in children of ... | 1984 | 6093500 |