Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| ultrastructure of epididymal epithelium in equus caballus. | the ultrastructure of the epithelial lining of the ductuli efferents and the ductus epididymis in the horse (equus caballus) is described. several types of cells can be distinguished: ciliated and non-ciliated cells make up the epithelium of the ductuli efferents, whereas principal, apical and basal cells are found in the ductus epididymis. the observations are compared with those made in other species, in particular in the donkey (equus asinus), and the possible functional roles of the differen ... | 1993 | 8465967 |
| interaction of a trypsin-like enzyme of porphyromonas gingivalis w83 with antithrombin iii. | we have previously observed that trypsin-like activity in porphyromonas gingivalis culture supernatants is inhibitable by the plasma arg-serpin antithrombin iii (atiii). this report demonstrates that a partially purified p. gingivalis trypsin-like enzyme (m(r) 47,000) is inhibited by atiii with an association rate constant (k(ass)) of 5.65 x 10(4) m-1 s-1 but does not form sds-stable complexes. heparin enhances the k(ass) and stabilizes the complexes but in either case such inhibition is tempora ... | 1993 | 8486244 |
| analysis of four microsatellite markers on the long arm of chromosome 9 by meiotic recombination in flow-sorted single sperm. | meiotic recombination in flow-sorted single sperm was used to analyze four highly polymorphic microsatellite markers on the long arm of chromosome 9. the microsatellites comprised three tightly linked markers: 9cmp1 (d9s109), 9cmp2 (d9s127), and d9s53, which map to 9q31, and a reference marker, ass, which is located in 9q34.1. haplotypes of single sperm were assessed by using pcr in a single-step multiplex reaction to amplify each locus. recombinant haplotypes were identified by their relative i ... | 1993 | 8503451 |
| implantation of a programmable atrioventricular pacemaker in a donkey with complete atrioventricular block and syncope. | 1993 | 8508758 | |
| linkage analysis in british and french families with idiopathic torsion dystonia. | idiopathic torsion dystonia is most commonly caused by an autosomal dominant gene or genes with reduced penetrance. an idiopathic torsion dystonia locus has been mapped to chromosome 9q34 in one large non-jewish and several jewish kindreds in the usa. linkage analysis was performed in 27 (26 british, one french) small families with idiopathic torsion dystonia, three of which were ashkenazi jewish, using the highly polymorphic loci argininosuccinate synthetase (ass) and abelson oncogene (abl) whi ... | 1993 | 8513401 |
| indirect immunofluorescence in the investigation of rapidly progressive sensorineural hearing loss and menière's disease. | being aware of the conservation of antigenicity, we performed indirect immunofluorescence on non fixed non decalcified frozen hamster's cochlea. once killed, the heads of the hamsters were immediately dipped into liquid nitrogen and then stored at -20 degrees c until cutting. the sections were done at the same temperature, with tissue-tek embedding the heads to avoid breaking, using a sharp tungsten knife. the immunofluorescence itself was performed with the sera of the patients which were revea ... | 1993 | 8517134 |
| presence of cd4+ and cd8+ t cells and expression of mhc class i and mhc class ii antigen in horses with borna disease virus-induced encephalitis. | tissues from 9 horses and 1 donkey suffering from natural borna disease were investigated immunomorphologically. lymphocytic inflammatory reactions and increased expressions of mhc class i and class ii antigen were found in the brain as well as in the trigeminal and olfactory system. perivascular inflammatory infiltrates were dominated by cd4+ t cells, whereas the majority of cd8+ t cells were disseminated intraparenchymally. no evidence of inflammation was found in the retina. borna disease vir ... | 1995 | 8520721 |
| physical characterization of mmvf for risk assessment. | size and other physical properties of mmvf play a central role in risk assessment. they can be affected by, for example, conditions during manufacturing, and preparation prior to administration to experimental animals or cells. it is suggested that a necessary requirement for stating that an experiment has been repeated should be documented evidence that: (i) the administered fibres are alike when analysed with not less than a minimum number of well-established methods on single fibre and on bul ... | 1995 | 8526398 |
| survival and morphology of isolated pancreatic acinar cells from rats with induced acute pancreatitis are not improved with anti-inflammatory drugs. | the influence from anti-inflammatory drugs on cellular damage of pancreatic acinar cells after induction of an acute pancreatitis (ap) in a rat model was investigated. necrotizing pancreatitis was induced by retrograde instillation of trypsin solution in the pancreatic duct (group i). the severity of inflammation was determined using morphological and histological parameters 6, 24, and 48 h after induction of the necrotizing pancreatitis. after isolation of acinar cells, the degree of damage was ... | 1995 | 8530830 |
| distribution and characterization of the melatonin receptors in the hypothalamus and pituitary gland of three domestic ungulates. | with some exceptions, in most of the mammals the pituitary pars tuberalis and the hypothalamic suprachiasmatic nuclei are reportedly the main targets for the pineal hormone melatonin. however, it is not known if the conspicuous diversity in the distribution pattern of melatonin binding sites in these areas depicts differences in reproductive behavior observed in the seasonally breeding species in the temperate zones. we explored the distribution and the characteristics of melatonin binding sites ... | 1995 | 8531051 |
| detection of leakage in inflatable genitourinary devices. | improved manufacturing techniques and stronger materials have significantly reduced but not eliminated the incidence of hydraulic leakage in the inflatable genitourinary devices. this study was designed to test the efficacy of pressure dissipation and volume loss as potential tests for the detection of site-specific hydraulic leakage in the inflatable penile prosthesis (ipp) and the artificial sphincter (as) and compare their efficacy with the current standard--the ohmmeter technique. | 1996 | 8560671 |
| transforming growth factor beta 1 expression in the endometrium of the mare during placentation. | in situ hybridization, northern blotting, and immunohistochemical techniques were used to study the expression of transforming growth factor beta 1 (tgf beta 1) in the endometrium of the mare during the first 150 days of pregnancy (term = 330-340 days). in situ hybridization using an oligonucleotide (45mer) probe, based on a homologous region within all known mammalian tgf beta 1 dna sequences, demonstrated tgf beta 1 mrna accumulation in the glandular and lumenal epithelial cells of the endomet ... | 1995 | 8562058 |
| equine pulmonary disease: a case control study of 300 referred cases. part 2: details of animals and of historical and clinical findings. | examination of historical and clinical details of 270 adult horses suffering from a variety of mainly chronic pulmonary diseases showed that the chronic obstructive pulmonary disease (copd) group (median age 9 years) were the oldest, and that the copd, chronic idiopathic hypoxaemia and exercise induced pulmonary haemorrhage (eiph) groups had the longest duration of disease (median durations 7, 12 and 9 months, respectively) with a median disease duration of 2 months for the remaining horses. a h ... | 1995 | 8565938 |
| inverted repeats are necessary for circularization of the mouse testis sry transcript. | circular non-polyadenylated rna molecules have been identified as stable transcription products of the human ets-1 and mouse sry genes. rna circularization has been proposed to require two steps. the first step utilizes intramolecular base pairing to produce a transient stem-loop structure. the second step involves splicing a downstream donor splice site (dss) to a now closely appositioned upstream acceptor splice site (ass) within the loop. we demonstrate that the presence of long inverted repe ... | 1995 | 8566785 |
| the argg gene of streptomyces clavuligerus has low homology to unstable argg from other actinomycetes: effect of amplification on clavulanic acid biosynthesis. | the argg gene of streptomyces clavuligerus (scl) has been cloned by complementation of argg mutants of escherichia coli and s. lividans (sl). the argg nucleotide (nt) sequence showed that it corresponds to a new type of argg different from the corresponding genes of s. coelicolor (sco) and sl. it encodes a 43,250-da protein that showed higher similarity to argininosuccinate synthetases (ass) from methanococcus vannielii and methanosarcina barkeri than to ass deduced from other streptomyces argg. ... | 1995 | 8566818 |
| [response to the letter by k. schrör on: prevention of reinfarction with 100 mg or 30 mg ass daily]. | 1995 | 8578789 | |
| the sedative and analgesic effects of detomidine (domosedan) in donkeys. | detomidine (domosedan) was administered to four groups of donkeys, using four different dosages (5, 10, 20 and 40 micrograms/kg bwt) intravenously. the drug provided adequate sedation at dosages of 5 and 10 micrograms/kg bwt. sedation deepened only slightly by increasing the dose. analgesia was considered good with a dose of 20 micrograms/kg, and 40 micrograms/kg provided a deep analgesia associated with a longer duration. no significant changes had been observed in haematocrit (pcv), haemoglobi ... | 1995 | 8578910 |
| [aspirin dosage for prevention of cerebral infarct: arguments for low dosage]. | acetylsalicylic acid (ass) is one of the best examined substances used in secondary prevention after tia and stroke. since different strategies and measurement variables were used in numerous randomised, double-blind, placebo-controlled studies (one end-variable, such as non-fatal stroke, myocardium infarction and vascular mortality, or combined end-variables, such as tia, stroke and death), meta-analysis was necessary to prove that ass resulted in about 22% reduction of secondary stroke. there ... | 1995 | 8584072 |
| [dna fingerprinting in wild equid and poitou ass breeding]. | 1995 | 8584876 | |
| sexual and in-contact transmission of asinine strain of equine arteritis virus among donkeys. | two in a group of five naturally seropositive donkey stallions were found to shed equine arteritis virus (eav) in their semen as demonstrated by virus isolation. direct intramuscular inoculation of sonicated semen from one virus-shedding stallion (s3) caused clinical disease in two donkeys from which virus was recovered and in which seroconversion was detected. sexual transmission was confirmed in two mares mated to s3 when after a febrile response during which eav was isolated from huffy coats ... | 1995 | 8586720 |
| cyanide poisoning in two donkeys. | in november 1994 2 donkeys died acutely in a pasture at danby, new york. at necropsy at the new york state college of veterinary medicine, cornell university, no significant gross or histopathological lesions were found in either donkey. after the death of the second donkey, a toxic cause was suggested. stomach contents submitted for toxicologic analysis from the second donkey were positive for cyanide. together with the history and clinical signs, this result provided the basis for a diagnosis ... | 1995 | 8588299 |
| pharmacokinetics, intramuscular bio-availability, and bioequivalence of amoxycillin in donkeys. | the disposition kinetics of intravenously (i.v.) administered amoxycillin sodium (10 mg/kg) was determined in four adult donkeys. the elimination half-life (t1/2 beta) of 47.3 +/- 5.1 min, the apparent volume of distribution (varea) of 0.325 +/- 0.093 l/kg and the total body clearance (clb) of 4.76 +/- 1.33 ml/min.kg were very close to the corresponding values reported for the horse injected i.v. with amoxycillin sodium. it was evident that because of the rapid rate of drug elimination, limited ... | 1995 | 8592903 |
| prevalence in india of dermatophilus congolensis infection in clinical specimens from animals and humans. | a total of 257 samples (from 51 cattle, 43 buffalo, 32 goats, 25 dogs, 23 horses, 14 fowl, 9 camels, 7 rabbits, 5 donkeys, 4 antelopes, 3 pigs, 2 monkeys, 1 bear and 38 humans, all with cutaneous disorders) were examined for the presence of dermatophilus congolensis using standard microbiological techniques. dermatophilus was identified in 14 specimens (5.45%) both by direct microscopy and by cultural isolation of the pathogen from cutaneous specimens. the infection was recorded in 2 humans, 6 c ... | 1995 | 8593415 |
| intra- and inter-observer agreement of brain mri lesion volume measurements in multiple sclerosis. a comparison of techniques. | the measurement of mri lesion load in multiple sclerosis is increasingly being used to evaluate the natural history of the disease and to monitor the efficacy of treatments. if, as might occur in multicentre studies, lesion load is measured by several observers in different patients or by the same observer in serial scans, it would be necessary to utilize a technique which provides results with high inter- and intra-observer agreements. this study was performed to evaluate the intra- and inter-o ... | 1995 | 8595488 |
| glutamine increases argininosuccinate synthetase mrna levels in rat hepatocytes. the involvement of cell swelling. | glutamine, one of the most efficient substrates in the urea cycle, was found to induce the accumulation of argininosuccinate synthetase (ass) mrna in primary cultured rat hepatocytes. the inducing action of glutamine was obtained at various stages of development and a half-maximal effect was observed at about 3 mm glutamine. this effect was apparent from 6 h and persisted for at least 48 h. nh4cl addition up to 5 mm did not significantly change the ass mrna level. like glutamine, hypoosmotic med ... | 1996 | 8617286 |
| inhibition of borrelia burgdorferi-bound fibrinolytic enzymes by alpha2-antiplasmin, pai-1 and pai-2. | lyme disease is caused by borrelia burgdorferi. human plasminogen and urokinase-type plasminogen activator bind to the surface of the spirochete where plasmin is generated. we have suggested that bound urokinase and plasminogen are utilized by the organism to disseminate. we tested whether the physiological inhibitors of urokinase, plasminogen activator inhibitor-1 and -2 (pai-1, pai-2), could regulate the activity of spirochete-bound urokinase. the k(ass) of pai-1 and pai-2 for bound urokinase ... | 1996 | 8645243 |
| inhibition of neutrophil elastase by the alpha1-proteinase inhibitor-immunoglobulin a complex. | neutrophil elastase is thought to be involved in cartilage destruction occurring in rheumatoid arthritis despite the local presence of alpha1-proteinase inhibitor. part of synovial fluid alpha1-proteinase inhibitor forms a mixed disulfide with immunoglobulin a, which has been postulated to lack inhibitory activity. we show here that the immunoglobulin-inhibitor complex tightly inhibits neutrophil elastase and cathepsin g, bovine pancreatic trypsin and chymotrypsin, and porcine pancreatic elastas ... | 1996 | 8647251 |
| if you assume, you can make an ass out of u and me': a decade of the disector for stereological counting of particles in 3d space. | the year 1984 was a watershed in stereology. it saw the introduction of highly efficient and unbiased design-based methods for counting the number of arbitrary objects in 3-dimensional (3d) space using 2d sectional images. the only requirement is that the objects be unambiguously identifiable on parallel sections or successive focal planes. the move away from the ¿assumption-based' and ¿model-based' methods applied previously has been a major scientific advance. it has led to the resolution of s ... | 1996 | 8655396 |
| simulation studies of african horse sickness and culicoides imicola (diptera:ceratopogonidae). | a simulation model of african horse sickness in spain was developed to investigate what factors affect the likelihood of an epidemic after the introduction of the virus. the model included 2 host species (horses and donkeys) and 1 vector species (culicoides imicola kieffer). latin hypercube sampling was used for sensitivity analysis of the model, to include uncertainty in parameter estimates. in general, if an epidemic occurred most hosts were infected. the peak prevalence in midges was low, and ... | 1996 | 8667377 |
| cloning and analysis of the cdna for the common alpha-subunit of the donkey pituitary glycoprotein hormones. | reverse transcription-pcr was used to clone the coding region of the donkey (equus asinus) glycoprotein hormone alpha-subunit transcript from pituitary gland rna. the donkey alpha-subunit sequence demonstrated considerable identity with the horse (97% at the nucleotide level), confirming the very close evolutionary linkage between these two species. the predicted amino acid sequence revealed that the donkey alpha-subunit has the same unusual c-terminus as the horse alpha-subunit, when compared w ... | 1996 | 8672238 |
| estimation of the liveweight and body condition of working donkeys in morocco. | the age, sex, liveweight and body measurements (heart girth, umbilical girth, height, length from elbow to tuber ischii and circumference of the foreleg cannon bone) of 516 donkeys used to transport goods in morocco were recorded. there were few donkeys over 12 years of age. for adult donkeys weighing from 74 to 252 kg, the best equation with only one variable for predicting liveweight was: liveweight (kg) = heart girth (cm)2.65/2188. the inclusion of two variables improved the prediction margin ... | 1996 | 8686139 |
| [distribution of borna disease virus in naturally infected animals with clinical disease]. | borna disease (bd) is a naturally occurring enzootic encephalomyelitis of horses and sheep. the aetiological agent, borna disease virus (bdv) is an unclassified, neurotropic, negative stranded rna virus. the study aimed at providing further information on bd of naturally infected animals. samples obtained from 20 animals (18 horses, 1 donkey, 1 sheep) were investigated by a series of virological and molecular biological tests. the highly sensitive reverse transcription-polymerase chain reaction ... | 1996 | 8694747 |
| remotely delivered immunocontraception in free-roaming feral burros (equus asinus). | regulation of local overpopulations of free-roaming feral equids is in demand worldwide for ecological balance and habitat preservation. contraceptive vaccines have proven effective in feral horses, which breed seasonally, but no data are available for equids such as the burro, which is reproductively active all year round. in the present study, 27 individually identified female feral burros (equus asinus) roaming free in virgin islands national park (st john, us virgin islands; lesser antilles) ... | 1996 | 8699431 |
| enzymatic properties and inhibition by single-stranded autonomously replicating sequences of adenylosuccinate synthase from saccharomyces cerevisiae. | adenylosuccinate synthase (ass) from saccharomyces cerevisiae has been shown to bind specifically to the t-rich side of the autonomously replicating sequence (ars) core consensus sequence [zeidler, r., hobert, o., johannes, l., faulhammer, h. & krauss, g. (1993) j. biol. chem. 268, 20191-20197]. we have cloned and sequenced the gene for ass and have studied in detail the enzymatic properties and dna-binding activity of ass. the deduced amino acid sequence of the yeast ass is highly similar to th ... | 1996 | 8706758 |
| [identification and diagnosis of taylorella equigenitalis by a dna amplification method (pcr)]. | a polymerase chain reaction (pcr) for identification of taylorella equigenitalis was developed. the oligonucleotide primers are based on the dna sequence of the rrs gene of t. equigenitalis, encoding for the 16s ribosomal rna. analysis of 21 strains of t. equigenitalis from england, usa and switzerland showed an amplification product of 410 bp with identical sau3a restriction profile. the sensitivity of the pcr-assay was estimated to detect 50 to 500 bacteria of t. equigenitalis in a mixture wit ... | 1996 | 8721184 |
| ["arbitrarily primed pcr". or: chance in the service of science]. | "arbitrarily primed pcr" (ap-pcr) methods are based on the amplification of dna with arbitrarily selected primers. in the present review article two selected applications of this methodical approach are summarized. using the rapd ("random amplified polymorphic dna") technique the genetic variability of different organisms can be analyzed by generating a genomic fingerprint. echinococcus granulosus isolates (metacestodes) from spain and switzerland were comparatively characterized by the use of t ... | 1996 | 8721188 |
| nucleotide sequence of exons 5 to 9 of the p53 tumour-suppressor gene of the horse (equus caballus). | an evolutionary conserved 1.3 kb fragment corresponding to the horse p53 tumour suppressor gene was pcr amplified, cloned and the nucleotide sequence determined. the p53 fragment encoded exons 5 to 9 and the intervening introns. the nucleotide sequence and the predicted aminoacid sequence showed a high level of homology with human and donkey p53 sequences. | 1996 | 8722575 |
| pathogenetic mechanism and prevalence of the stable atlantoaxial subluxation in rheumatoid arthritis. | to study the pathogenetic mechanisms responsible for and prevalence of stable atlantoaxial subluxation (aas). | 1996 | 8724293 |
| pharmacokinetics and pharmacodynamics of phenylbutazone and oxyphenbutazone in the donkey. | 1996 | 8735424 | |
| pharmacokinetics of gentamicin in donkeys. | 1996 | 8735430 | |
| dehydration and rehydration in donkeys: the role of the hind gut as a water reservoir. | body fluid distribution was measured in three donkeys, fully hydrated, following dehydration and after being rapidly rehydrated. in twenty other donkeys that were slaughtered to supply food for predators in a safari zoo, the water content in the different compartments of the gastrointestinal tract (git) was assessed. prior to being slaughtered, four of the animals were fully hydrated, four dehydrated and 12 dehydrated, rehydrated and then slaughtered and examined, four at 1, for at 3 and four at ... | 1994 | 8736073 |
| nucleotide sequence of exons 5 to 9 of the p53 tumour-suppressor gene of the donkey (equus asinus). | the evolutionary conserved region of the equine homologue of the p53 gene from the donkey genome was pcr amplified and cloned. the 1380 bp fragment consisted of exons 5 to 9 and the intervening introns. the exonic and intronic dna sequences showed a variable but high level of homology with previously published human sequences. the aminoacid sequences corresponding to the evolutionary conserved domains ii, iii, and v were identical to the human regions, whilst domain iv was 96% homologous. | 1995 | 8746464 |
| [argininosuccinate synthetase (ass)]. | 1995 | 8753462 | |
| failure of endometrial cup development in the donkey-in-horse model of equine abortion. | the mature preinvasive chorionic girdles of horse, mule, donkey and extraspecies donkey-in-horse conceptuses, and the very young endometrial cups on d 37 of gestation in mares carrying horse, mule and transferred donkey-in-horse conceptuses, were compared histologically and ultrastructurally to determine possible mechanisms underlying failure of endometrial cup development in the donkey-in-horse model of equine abortion. the progenitor chorionic girdle from the failing donkey-in-house pregnancy ... | 1996 | 8763475 |
| [paramphostomid infestation in equids in egypt]. | the investigation of 156 donkeys in the area of the veterinary faculty of the tanta university in kafr el-sheikh showed that 49 animals (31.41%) were infected with trematodes, 34 donkeys (21.80%) served as hosts for gastrodiscus aegyptiacus, 22 (14.10%) were infected with fasciola gigantica und 7 (4.49%) with both trematodes. 6 of 40 examined horses (15.0%) showed monoinfections with g. aegyptiacus only. because of the fragmentary knowledge on these paramphistomides of equids, some aspects conce ... | 1996 | 8765538 |
| [dysmenorrhea]. | primary dysmenorrhea is very frequent in ovulating women; it can even become a disease. in some cases, but not always, it is preceded by premenstrual tensions. secondary dysmenorrhoea should be clearly differentiated, because it is a symptom of uterine abnormalities or adnexal diseases, whereas primary dysmenorrhoea is an entity in itself. the most frequent cause of secondary dysmenorrhoea is endometriosis. dysmenorrhea membranacea is a rare event, but should not be forgotten. primary dysmenorrh ... | 1996 | 8767549 |
| [malaria knowledge and practice. medical study in songhay-zarma (niger)]. | two randomized studies were performed in 1992 and 1994 in the niger river valley where malaria transmission is thought to be permanent and is reinforced during the rainy season. the sample covered 114 families either in niamey, the capital of niger, or in karma, a rural village 20 km to the west, and its surroundings. the questionnaire contained closed and open questions on the perception of malaria causes, treatment and prevention, including the use of mosquito bed nets. most of the 114 familie ... | 1995 | 8777545 |
| characterization of human wild-type and mutant argininosuccinate synthetase proteins expressed in bacterial cells. | argininosuccinate synthetase (ass) is a urea cycle enzyme with a tetrameric structure composed of identical subunits. citrullinemia is an autosomal recessive disease caused by a deficiency of ass. we have previously identified 20 mutations in ass mrna of human classical citrullinemia. however, it is difficult to evaluate the effects of each mutation on the enzyme structure and function, since most of the patients are compound heterozygotes. in the present study, wild-type ass and 12 mutant asss ... | 1994 | 8792870 |
| improvement of the tissue integration of a new modified polytetrafluoroethylene prosthesis: mycro mesh. | we studied the behaviour of the different tissue interfaces formed on a new type of prosthesis used for the repair of abdominal wall defects, mycro mesh (w. l. gore and ass., flagstaff, az, usa), which consists of perforated layers of polytetrafluoroethylene (ptfe). in 20 new zealand white rabbits, a full-thickness (except skin) 7 cm x 5 cm defect was created in the anterior abdominal wall. the defects were repaired with a prosthetic implant (mycro mesh) that was placed in direct contact with ab ... | 1996 | 8805973 |
| hypertrophic osteopathy (marie's disease) in equidae: a review of twenty-four cases. | the case records of 23 horses and one donkey affected by hypertrophic osteopathy (ho) (marie's disease) were reviewed. all affected animals presented with limb swellings, which were bilaterally symmetrical and usually involved both fore- and hindlimbs. associated signs included stiffness/lameness and weight loss. radiological features included periosteal new bone formation over the diaphyses and metaphyses of affected bones. the metacarpal and metatarsal bones were most frequently affected. arti ... | 1996 | 8818590 |
| inhibition of coagulation factors by recombinant barley serpin bszx. | barley serpin bszx is a potent inhibitor of trypsin and chymotrypsin at overlapping reactive sites (dahl, s.w., rasmussen, s.k. and hejgaard, j. (1996) j. biol. chem., in press). we have now investigated the interactions of bszx with a range of serine proteinases from human plasma, pancreas and leukocytes, a fungal trypsin and three subtilisins. thrombin, plasma kallikrein, factor viia/tissue factor and factor xa were inhibited by bszx at heparin independent association rates (k(ass)) of 4.5 x 1 ... | 1996 | 8843156 |
| efficacy of triclabendazole against fasciola hepatica in the donkey (equus asinus). | 1996 | 8863404 | |
| survival analysis approach to risk factors associated with hyperlipemia in donkeys. | to investigate the effect of gender, body condition, and age as risk factors for the development of hyperlipemia in a population of donkeys. | 1996 | 8870744 |
| the mitochondrial dna molecule of sumatran orangutan and a molecular proposal for two (bornean and sumatran) species of orangutan. | the complete mitochondrial dna (mtdna) molecule of sumatran orangutan, plus the complete mitochondrial control region of another sumatran specimen and the control regions and five protein-coding genes of two specimens of bornean orangutan were sequenced and compared with a previously reported complete mtdna of bornean orangutan. the two orangutans are presently separated at the subspecies level. comparison with five different species pairs-namely, harbor seal/grey seal, horse/donkey, fin whale/b ... | 1996 | 8875856 |
| the complete mitochondrial dna (mtdna) of the donkey and mtdna comparisons among four closely related mammalian species-pairs. | the nucleotide sequence of the complete mitochondrial genome of the donkey, equus asinus, was determined. the length of the molecule is 16,670 bp. the length, however, is not absolute due to pronounced heteroplasmy caused by variable numbers of two types of repetitive motifs in the control region. the sequence of the repeats is (a) 5'-cacaccca and (b) 5'-tgcgcgca, respectively. the order of (a) and (b) can be expressed as {n[2(a)+(b)]+m(a)}. in 32 different clones analyzed the number of n and m ... | 1996 | 8875857 |
| synteny mapping in river buffalo. | the cosegregation of ten coding loci has been investigated, in a panel of 37 somatic cell hybrids resulting from the fusion of a hamster cell line and river buffalo lymphocytes, by use of southern hybridization technique. five syntenic groups, tcrb-pgy3, ass-abl, fuca1p-cryg, mbp-yes1, and cgn1-acta1, previously assigned to cattle as u13, u16, u17, u28, and u29 respectively, were also found to be syntenic in buffalo. based on the extensive syntenic conservation and banding homology between cattl ... | 1996 | 8875891 |
| a sequence similarity search algorithm based on a probabilistic interpretation of an alignment scoring system. | we present a probabilistic interpretation of local sequence alignment methods where the alignment scoring system (ass) plays the role of a stochastic process defining a probability distribution over all sequence pairs. an explicit algorithms is given to compute the probability of two sequences given and ass. based on this definition, a modified version of the smith-waterman local similarity search algorithm has been devised, which assesses sequence relationships by log likelihood ratios. when te ... | 1996 | 8877503 |
| nationwide serological survey of equine influenza in nigeria. | the objective of this work was to examine the incidence of equine influenza viruses in the equine population of an area of tropical africa where equine influenza virus activity has recently been reported for the first time. a serological survey of sera from horses and donkeys from regions of nigeria taken from 1990 to 1993 was carried out and the results obtained were com-pared with equine sera from western europe (ireland). the sera were assayed for presence of antibodies by both haemagglutinat ... | 1996 | 8881415 |
| [prevalence of rhinoestrus usbekistanicus (gan 1947) in donkeys (equus asinus) in senegal]. | a survey performed in dakar (senegal) showed, for the first time, the presence of rhinoestrus usbekistanicus in donkeys in the south of the sahara desert. out of the 138 heads examined between november and june, 84% were infected by a mean burden of 15.9 larvae (9.7 l1, 1.8 l2 and 4.1 l3). there is a hypobiotic period starting in march during the dry season. | 1996 | 8881418 |
| a radioimmunoassay for the determination of tipredane in human plasma. | a sensitive method for the determination of tipredane in human plasma has been developed. prior to radioimmunoassay, proteins are removed from plasma by precipitation with acetonitrile. a [125i]iodohistamide derivative of tipredane is used as a heterogeneous radioligand. the primary antiserum is raised in sheep against a tipredane (o-carboxymethyl) oxime-bovine serum albumin conjugate. donkey anti-sheep igg antiserum is used as the secondary antiserum in a double antibody separation procedure. t ... | 1996 | 8895073 |
| the complete mitochondrial dna sequence of the greater indian rhinoceros, rhinoceros unicornis, and the phylogenetic relationship among carnivora, perissodactyla, and artiodactyla (+ cetacea). | the sequence (16,829 nt) of the complete mitochondrial genome of the greater indian rhinoceros, rhinoceros unicornis, was determined. like other perissodactyls studied (horse and donkey) the rhinoceros demonstrates length variation (heteroplasmy) associated with different numbers of repetitive motifs in the control region. the 16,829-nt variety of the molecule includes 36 identical control region motifs. the evolution of individual peptide-coding genes was examined by comparison with a distantly ... | 1996 | 8896369 |
| don't dissect use the disector! 'if you assume, you can make an ass out of u and me': a decade of the disector for sterological counting of particles in 3d space. | 1996 | 8906439 | |
| preliminary pharmacokinetic and pharmacodynamic studies on flunixin meglumine in donkeys. | 1996 | 8908727 | |
| comparative morphology of the pectinate ligaments of domestic mammals, as observed under the dissecting microscope and the scanning electron microscope. | the pectinate ligaments of ten horses, two donkeys, five oxen, five sheep, ten goats, five dogs, five cats, thirty pigs and two rabbits were studied under the stereomicroscope and the scanning electron microscope. in the horse and the donkey, the pectinate ligament was very prominent and was characterized by sturdy interconnected strands and relatively small intertrabecular spaces. the pectinate ligaments of ruminants were composed of shorter strands, separated by relatively larger spaces. fusio ... | 1996 | 8915997 |
| transmission of the south african asinine strain of equine arteritis virus (eav) among horses and between donkeys and horses. | lateral and sexual transmission of eav among horses and lateral transmission between donkeys and horses were attempted by experimental infection with the south african asinine strain. clinical, immunological and virological responses were evaluated. all intramuscularly inoculated horses developed very mild clinical signs, were viraemic, shed virus from nasopharynx, and seroconverted. lateral infection was demonstrated in one in-contact mare. reinfection of two stallions by intranasal instillatio ... | 1996 | 8917855 |
| heterophile antibodies to chicken erythrocytes in sheep infected with trypanosoma congolense. | high hemagglutinin titres against chicken erythrocytes were detected in the sera of trypanosoma congolense-infected sheep. adsorption of sheep sera with solubilized t. congolense resulted in marked reduction of hemagglutinin titre. heat inactivation of the sera at 56 degrees c for 30 min had no demonstrable effects on the hemagglutinin titre. sera collected from the sheep before trypanosome infection did not agglutinate chicken erythrocytes. on the other hand, erythrocytes of horse, donkey and d ... | 1996 | 8917863 |
| analysis of the long terminal repeat from a cytopathic strain of equine infectious anemia virus. | sequential passage of the tissue culture-adapted prototype strain of eiav in fetal donkey dermal (fdd) cell cultures generated a virus stock which exhibits cytopathic effects in fdd cell cultures. in this study, the effects of the long terminal repeat (ltr) region on virus replication and cytopathogenicity were examined. the fdd-adapted virus ltr was found to contain a number of base pair mutations and a large insertion within the u3 region in comparison with the previously characterized ltr, la ... | 1996 | 8918926 |
| prevalence of sarcocysts in livestock of northwest ethiopia. | a survey of sarcocystis was conducted in cattle, sheep, goats, donkeys and chickens. a total of 671 haematoxylin-eosin (h-e) stained muscle tissue samples, including diaphragm, masseter, cardiac and oesophageal musculatures were examined. additionally, cardiac muscle samples from 40 fetuses were included. an infestation rate of 93% in sheep, 82% in cattle, 81% in goats, 16.6% in donkeys and 6.6% in chickens was noted. the infestation rate of diaphragm, masseter, cardiac and oesophageal musculatu ... | 1996 | 8919969 |
| pharmacokinetics of ketoprofen in the donkey (equus asinus). | the pharmacokinetic parameters of ketoprofen were determined in four donkeys after a single intravenous injection of a dose of 2.2 mg/kg body weight. the total body clearance (clb) was 414.0 +/- 98.70 ml/h/kg (mean +/- sd), the volume of distribution at steady state (vss) 263.10 +/- 55.43 ml/kg and the elimination half-life 1.30 +/- 0.75 h. these values were compared to those obtained in horses. | 1996 | 8921728 |
| alterations in glomerular anionic sites in the autologous phase of canine anti-glomerular basement membrane nephritis. | there have been a few studies on canine nephrotoxic glomerulonephritis produced by anti-glomerular basement membrane serum (agbm), but these reports have not focused on an alteration in the charge properties of glomerular basement membrane (gbm). in this study, rabbit agbm or normal rabbit serum (nrs) was given intravenously (2 ml/kg body weight) to 16 male beagle dogs. an alteration of anionic sites (ass) of gbm was studied quantitatively using polyethyleneimine as a cationic probe by electron ... | 1996 | 8923685 |
| [preparation and study of recombinant strains of venezuelan equine encephalomyelitis virus expressing the pres2-s gene of the hepatitis b virus]. | venezuelan equine encephalomyelitis (vee) virus-based vectors for expression of heterologous genes have been constructed using full-length cdna copy of the interstrain recombinant virus (trinidad donkey and 230 strain). gene cassettes carrying the subgenomic mrna promoter of vee virus and the pres2-s gene of hepatitis b virus (hbv) were inserted before or after the genes of structural viral proteins. live virus stocks were obtained by transfection of chick embryo fibroblasts with in vitro transc ... | 1996 | 8928499 |
| anisoosmotic regulation of hepatic gene expression. | the effect of anisoosmolarity on the abundance of various mrna species was examined in perfused rat liver and h4iie rat hepatoma cells. hyperosmotic exposure (385 mosmol/l) of isolated rat livers increased mrna levels for tyrosine aminotransferase (tat) by 246% and those for phosphoenolpyruvate carboxykinase (pepck) by 186%, whereas hypoosmotic exposure (225 mosmol/l) decreased their levels to 43% and 42%, respectively. mrna levels for fructose-1,6-bisphosphatase (fbp), argininosuccinate lyase ( ... | 1996 | 8929814 |
| smooth-pursuit eye movement and saccadic intrusions in obsessive-compulsive disorder. | although several reports agree that smooth-pursuit eye movement (spem) is abnormal in some obsessive-compulsive disordered (ocd) patients, differences between treatments and lack of accuracy in control selection make the results controversial. although reduced gain seems the most accepted abnormality, the characteristics of saccadic disruption of smooth pursuit are as yet unspecified. spems in 21 ocd patients (dsm-iii-r) and 21 healthy subjects recruited from the community were studied through a ... | 1996 | 8931920 |
| essential thrombocythemia and pregnancy. | a review of the literature disclosed 106 pregnancies (preg.) in 57 women with essential thrombocythemia (et). the success rate (baby alive) was 57% (60 live births/106 preg.), the rate of miscarriage 43% (46 miscarriages/106 preg.). the most frequent complication was spontaneous abortion during the first trimester in 36% (38 abortions/106 preg.). other complications such as intrauterine death and stillbirth after the 28th week, which occurred in 5% (7/106), premature delivery in 8% (8/106), pre- ... | 1996 | 8951773 |
| use of donkeys and their draught performance in smallholder farming in zimbabwe. | animal traction constitutes the most important source of power for agricultural work in smallholder farming in zimbabwe. two studies, a survey and a short term on-farm trial were conducted to evaluate the use of donkeys as draught animals. the survey covered 59 households in 2 smallholder farming areas. for the on-farm trial, 12 donkeys and 12 cattle were spanned separately in teams of 4 animals to plough 40 m x 70 m plots of medium textured soil. the survey findings highlighted the drought tole ... | 1995 | 8966767 |
| endothelial cell dysfunction secondary to the adhesion of diabetic erythrocytes. modulation by iloprost. | we previously showed the correlation between the extent of vascular complications and erythrocyte adherence to endothelium in diabetes mellitus. the accumulation of advanced glycation end products (ages) on the erythrocyte surface in diabetes mediates their interaction with endothelial cells through a specific endothelial receptor for ages (rage). binding of diabetic erythrocytes to endothelial cells resulted in evidence of oxidant stress responsible for a range of cellular perturbations. in the ... | 1996 | 8971575 |
| kinetics of binding of antp homeodomain to dna analyzed by measurements of surface plasmon resonance. | the kinetics of binding of the antp homeodomain to three kinds of dna fragment were analyzed by measurements of surface plasmon resonance at various temperatures. non-specific and specific binding of the homeodomain to dna was examined. in the case of non-specific binding, the association rate constant (k(ass)) was estimated to be 1.41-2.62 x 10(5) m(-1) s(-1) and the dissociation rate constant (k(diss)) was 1.36-3.10 x 10(-2) s(-1), thus, the dissociation constant (kd) was 0.847-1.72 x 10(-7) m ... | 1996 | 8977123 |
| applications of pig zona pellucida immunocontraception to wildlife fertility control. | a unique application of pig zona pellucida (pzp) immunocontraception is the control of wildlife populations. a native pzp vaccine has been successfully applied to wild horse and donkey populations. a single annual booster inoculation was capable of maintaining contraception. seven consecutive years of pzp treatment in wild mares resulted in no detectable debilitating side effects, and reversibility of contraception has been documented among mares treated for up to 4 consecutive years. long-term ... | 1996 | 8984182 |
| long-chain fatty acids suppress the induction of urea cycle enzyme genes by glucocorticoid action. | in order to test the possibility that free fatty acids are the mediator of the abnormal expression of urea cycle enzyme genes in carnitine-deficient juvenile visceral steatosis (jvs) mice, the effects of fatty acids on urea cycle enzyme, carbamoylphosphate synthetase (cps) and argininosuccinate synthetase (ass), mrna levels were examined in rat primary cultured hepatocytes. addition of a synthetic glucocorticoid hormone, dexamethasone, caused increases in cps and ass mrnas. further addition of o ... | 1996 | 8985169 |
| observations on the prevalence of trypanosomosis in small ruminants, equines and cattle, in relation to tsetse challenge, in the gambia. | the prevalence of trypanosome infections in djallonké sheep and west african dwarf goats at different sites in the gambia showed a significant, positive correlation with contemporary assessments of tsetse challenge. a similar correlation was observed in village n'dama cattle which showed comparable prevalence values in the same areas. trypanosome prevalences also tended to be higher in horses and donkeys in areas with high tsetse challenge compared with sites with relatively few flies. a ranking ... | 1996 | 8988551 |
| comparative pharmacokinetics of phenylbutazone and its metabolite oxyphenbutazone in clinically normal horses and donkeys. | to compare plasma disposition of phenylbutazone and its metabolite oxyphenbutazone after i.v. administration of phenylbutazone in horses and donkeys. | 1997 | 8989496 |
| [alpha 2-adrenoreceptor agonists--horse or donkey?]. | 1996 | 8991465 | |
| clostridium pascui sp. nov., a new glutamate-fermenting sporeformer from a pasture in pakistan. | four strains of an obligately anaerobic spore-forming bacterium were isolated from soil samples from a donkey pasture in pakistan. comparative 16s rrna sequence analysis demonstrated that the strains are members of phylogenetic cluster i of the genus clostridium (collins et al. 1994). the strains are mesophilic, nonsaccharolytic, and nonproteolytic, utilize glutamate and histidine, and produce indole. acetate, butyrate, ethanol, hydrogen, and carbon dioxide are the products of fermentation. alth ... | 1997 | 8995820 |
| [endoparasites of donkeys and horses kept in communal housing in upper bavaria; species spectrum and incidence]. | in this epidemiological study of endoparasites 37 donkeys and 23 horses were included, which were examined coproscopically in regular intervals over a 15 month period. the animals derived from ten farms, in which regular prophylactic treatments with anthelmintics had been practiced at least for two years before this investigation. this study revealed the presence of at least twelve parasite species in donkeys, eimeria leuckarti, gasterophilus intestinalis, fasciola hepatica, anoplocephala perfol ... | 1996 | 8999593 |
| nosology of fetal hypokinesia sequence based on cns abnormalities: is there an aase-smith syndrome? | aase-smith syndrome (ass) is usually defined as a dominantly inherited combination of arthrogryposis, dandy-walker malformation and cleft palate. we describe a sporadic case of foetal akinesia with abnormal fossa posterior, fitting the diagnosis of ass, and discuss the nosology of this entity among syndromes with distal arthrogryposis. ass shows a "hybrid" phenotype: adults with mild ass could be classified as distal arthrogryposis, whereas severely affected newborns overlap with the marden-walk ... | 1996 | 9001811 |
| evidence for embryonic prostaglandin h synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis. | a mouse embryo culture model was used to determine whether embryonic prostaglandin h synthase (phs)-catalyzed bioactivation and resultant oxidative damage to embryonic protein and dna may constitute a molecular mechanism mediating phenytoin and benzo[a]pyrene teratogenesis. embryos were explanted from cd-1 mouse dams on gestational day 9.5 (vaginal plug = day 1) and incubated for either 4 h (biochemistry) or 24 h (embryotoxicity) at 37 degrees c in medium containing either phenytoin (20 microgra ... | 1997 | 9013124 |
| a fragment of the major histocompatibility complex class ii-associated p41 invariant chain inhibits cruzipain, the major cysteine proteinase from trypanosoma cruzi. | a peptide fragment derived from the p41 form of the invariant chain (ii) associated with the major histocompatibility complex (mhc) class ii molecule has been shown to inhibit the mammalian lysosomal cysteine proteinase, cathepsin l, and to be a novel cysteine proteinase inhibitor, distinct from cystatins. here we report that this same fragment also binds to and inhibits cruzipain, the cathepsin l-like enzyme from the protozoan parasite trypanosoma cruzi. the binding of the ii fragment to cruzip ... | 1997 | 9013899 |
| [jenner's cowpox vaccine in light of current vaccinology]. | two hundred years ago edward jenner inoculated james phipps with vaccinia and 181 years later smallpox had disappeared from the surface of the earth as a result of generalized vaccination. compared to the requirements of modern vaccinology, the procedures used by jenner and his successors, were extremely primitive because of an almost total lack of knowledge in the field of microbiology and immunology. the active principle of smallpox vaccine is vaccinia virus, which in many respects, differs fr ... | 1996 | 9027132 |
| a survey for antibodies to equine arteritis virus in donkeys, mules and zebra using virus neutralisation (vn) and enzyme linked immunosorbent assay (elisa). | a seroepidemiological survey of donkeys in south africa (n = 4300) indicated a wide distribution and increasing prevalence of antibodies to equine arteritis virus (eav). donkey sera inhibited equine arteritis virus infection in virus neutralisation (vn) tests and in elisa specifically bound to a recombinant antigen derived from the bucyrus isolate of eav. these results suggest that donkeys have been exposed to the same serotype of this virus as circulates among horses. a good correlation existed ... | 1997 | 9031862 |
| suppressed expression of the urea cycle enzyme genes in the liver of carnitine-deficient juvenile visceral steatosis (jvs) mice in infancy and during starvation in adulthood. | systemic carnitine-deficient juvenile visceral steatosis (jvs) mice exhibit decreased expression of some liver-selective genes including those for the urea cycle enzymes during the infantile period. at 25 days, carbamoylphosphate synthetase (cps) mrna level was remarkably low in the liver of jvs mice, and the hnf-4 and c/ebp-alpha mrna contents were also reduced. hnf-3 alpha and c/ebp-beta mrnas were slightly higher in the liver of jvs mice, and hnf-1 mrna remained normal. these results, togethe ... | 1997 | 9058209 |
| expression of horse and donkey lh in cos-7 cells: evidence for low fsh activity in donkey lh compared with horse lh. | horse (equus caballus) luteinizing hormone (elh) and chorionic gonadotrophin (ecg), which have the same amino acid sequence, are unusual in that, although they express only lh activity in equids, they express dual lh and fsh activities in all other species tested. donkey (equus asinus) lh (dklh) and cg (dkcg), which also share an identical peptide backbone, have been less well characterized and conflicting results concerning their fsh activity in heterologous species have appeared in the literat ... | 1997 | 9071957 |
| placental localization of relaxin in the pregnant mare. | in situ hybridization employing a crna probe derived from a 428-bp fragment of equine relaxin was used to localize relaxin mrna, and immunocytochemistry was used to localize relaxin itself, in tissues of the placenta-endometrium interface recovered between 33 and 153 days of gestation from mares carrying intraspecific horse, interspecific mule and extraspecific donkey conceptuses. immunocytochemical staining was also used to localize trophoblast-specific and class i major histocompatibility comp ... | 1997 | 9089772 |
| role and management of donkeys in samburu and turkana pastoralist societies in northern kenya. | a survey was carried out in northern kenya to obtain data on the role and management of donkeys in samburu and turkana pastoralist societies and to identify potential areas, if any, for interventions. sixty-seven women owning or closely associated with 583 donkeys were surveyed during july/august 1994. the median donkey herd sizes in samburu and turkana societies were 4 and 10 respectively. pack transport of water and domestic materials were the major reasons for keeping donkeys. donkey milk, me ... | 1997 | 9090018 |
| mutations and dna diagnoses of classical citrullinemia. | classical citrullinemia is an autosomal recessive disease caused by a genetic deficiency of argininosuccinate synthetase (ass). we have previously identified 20 mutations in ass mrna of human classical citrullinemia and already established the dna diagnosis of seven mutations as follows. by southern blot analysis, each of the alleles with exon 5 or 6 deletion in mrna appears to involve deletion of genomic dna from this region. five mutations involving r304w, g324s, ivs-6(-2) (delta ex7), ivs-13( ... | 1997 | 9090528 |
| [superselective spinal anesthesia for saphenectomy intervention. comparison of 2 concentrations of hyperbaric bupivacaine]. | high concentrations of intrathecal local anaesthetics may be neurotoxic. the purpose of this study was to compare the features of superselective spinal anaesthesia (ass) obtained with an equivalent dose (5 mg) of 0.5% (available now also in italy) and 1% hyperbaric bupivacaine. | 1996 | 9102589 |
| disposition of ampicillin sodium in horses, ponies and donkeys after intravenous administration. | 1992 | 9109963 | |
| wound infection caused by staphylococcus hyicus subspecies hyicus after a donkey bite. | staphylococcus hyicus subspecies hyicus has not previously been reported to cause human infections, but is a well known cause of diseases in a variety of animals. we report a wound infection following a donkey bite. | 1997 | 9112308 |
| apoptotic cell death is an important cause of neuronal injury in experimental venezuelan equine encephalitis virus infection of mice. | mice develop a fatal encephalomyelitis after infection with the trinidad donkey strain of venezuelan equine encephalitis (vee) virus. adult mice were inoculated intraperitoneally with vee virus and the brains were examined at different time points. morphological changes were assessed by histological staining. vee virus antigen was detected with immunoperoxidase staining, and dna fragmentation was evaluated in situ using the terminal deoxynucleotidyl transferase-mediated dutp-digoxigenin nick end ... | 1997 | 9113200 |
| longitudinal and cross-sectional studies to evaluate the risk of sarcoid associated with castration. | in order to investigate whether gender and castration have an effect on the time to the development of sarcoids, a retrospective study in a population of donkeys was conducted using survival analysis techniques. univariable kaplan meier product limit curves identified males as having significantly lower survival probability, or higher risk of developing sarcoids, than females (p < 0.01). cox's proportional hazard model was used to assess the effect of age at entry to the population whilst simult ... | 1997 | 9114958 |
| field trial evaluation of detomidine as a sedative and analgesic in horses with colic. | in this uncontrolled clinical study 12 investigators cooperated to evaluate the analgesic and sedative effect of detomidine (dormosedan; farmos group ltd; finland) in 234 horses with abdominal pain caused by colic. the study was designed to use each animal as its own control and to evaluate its response to the drug over a 60 min period. detomidine was given intravenously (i.v.) once in 169 cases (167 horses, 1 mule, 1 donkey) at a dose of 20 micrograms/kg bodyweight (bwt), and to 65 horses at 40 ... | 1989 | 9118092 |