Publications

immunohistochemical localization of kallikrein in salivary glands of the japanese monkey, macaca fuscata.	the immunofluorescence staining using anti-human urinary kallikrein polyclonal antiserum was intense in the luminal rim of the striated duct cells, but decreased in the excretory duct cells and was weak in the intercalated duct cells. western blot analysis demonstrated the monospecificity of the antiserum to glandular kallikrein in macaca submandibular gland homogenate. the staining was observed to a similar degree as that in salivary glands with long and numerous striated ducts in the following ...	1996	8712979
comparison of cerebellothalamic and pallidothalamic projections in the monkey (macaca fuscata): a double anterograde labeling study.	to address the question of segregated projections from the internal segment of the globus pallidus (gpi) and the cerebellar nuclei (cb) to the thalamus in the monkey, we employed a double anterograde labeling strategy combining the anterograde transport of horseradish peroxidase conjugated to wheat germ agglutinin (wga-hrp) with biotinylated dextran amine (bda) transport. the tissue was processed sequentially for wga-hrp, and then bda immunohistochemistry using two different chromogens. since th ...	1996	8725303
microsomal aldehyde oxygenase (maldo): purification and characterization of a cytochrome p450 isozyme responsible for oxidation of 9-anthraldehyde to 9-anthracenecarboxylic acid in monkey liver.	oxidative activity of 9-anthraldehyde (9-aa) to 9-anthracenecarboxylic acid in monkey liver was mainly located in microsomes. the reaction required nadph as an essential cofactor and was significantly inhibited by skf 525-a, metyrapone, disulfiram, and co, potent inhibitors of microsomal aldehyde oxygenase (maldo). two cytochrome p450 isozymes, named p450jm-a and p450jm-c, which mediate the oxidative biotransformation of 9-aa were purified from hepatic microsomes of untreated male and female jap ...	1996	8743560
microsomal aldehyde oxygenase (maldo): purification and characterization of a cytochrome p450 isozyme responsible for oxidation of 9-anthraldehyde to 9-anthracenecarboxylic acid in monkey liver.	oxidative activity of 9-anthraldehyde (9-aa) to 9-anthracenecarboxylic acid in monkey liver was mainly located in microsomes. the reaction required nadph as an essential cofactor and was significantly inhibited by skf 525-a, metyrapone, disulfiram, and co, potent inhibitors of microsomal aldehyde oxygenase (maldo). two cytochrome p450 isozymes, named p450jm-a and p450jm-c, which mediate the oxidative biotransformation of 9-aa were purified from hepatic microsomes of untreated male and female jap ...	1996	8743560
intrinsic connections in the macaque inferior temporal cortex.	intrinsic connections in the inferior temporal cortex were analyzed by making extracellular injections of biocytin in japanese macaques. analysis was focused mainly on the dorsal part of area te, in which a functional columnar organization has been shown. interlaminar connections were analyzed in coronal section after laminar-specific microinjections, and intralaminar connections were examined from tangential sections. after injections at various depths in the dorsal te, both axons and cell bodi ...	1996	8744437
neural mechanism of pressor action of nitric oxide synthase inhibitor in anesthetized monkeys.	intravenous injection of ng-nitro-l-arginine (l-na), a nitric oxide synthase inhibitor, elevated mean blood pressure by 29.0 +/- 4.9 mm hg and decreased heart rate by 40.7 +/- 5.6 beats per minute in anesthetized japanese monkeys (n = 6), whereas ng-nitro-d-arginine was without effect. after pretreatment with pentolinium, the magnitude of the pressure elevation by l-na was significantly less than that after pretreatment with phentol-amine. the reduced blood pressure by either of the pretreatment ...	1996	8794814
neural mechanism of pressor action of nitric oxide synthase inhibitor in anesthetized monkeys.	intravenous injection of ng-nitro-l-arginine (l-na), a nitric oxide synthase inhibitor, elevated mean blood pressure by 29.0 +/- 4.9 mm hg and decreased heart rate by 40.7 +/- 5.6 beats per minute in anesthetized japanese monkeys (n = 6), whereas ng-nitro-d-arginine was without effect. after pretreatment with pentolinium, the magnitude of the pressure elevation by l-na was significantly less than that after pretreatment with phentol-amine. the reduced blood pressure by either of the pretreatment ...	1996	8794814
myeloencephalitis associated with a viridans group streptococcus in a colony of japanese macaques (macaca fuscata).	five weaned immature japanese macaques (macaca fuscata), bred in captivity, showed nervous signs over a 12-month period. hemorrhagic cerebral infarcts with vasculitis were detected in four necropsied animals. the distribution and nature of the lesions were consistent with bacterial embolism, and a streptococcus isolate, biochemically similar to s. salivarius, was recovered from the cerebral lesions from three of the four necropsied macaques. treatment with antibacterial agents (enrofloxacin) imp ...	1996	8826016
the sites of origin and termination of afferent and efferent components in the lingual and pharyngeal branches of the glossopharyngeal nerve in the japanese monkey (macaca fuscata).	afferent and efferent components in the lingual and pharyngeal branches of the glossopharyngeal nerve (li and ph) of the japanese monkey (macaca fuscata) were examined. after injecting wheat germ agglutinin-conjugated horseradish peroxidase (wga-hrp) unilaterally into the central cut end of the li and ph, or into the stylopharyngeal muscle, labeled neuronal cell bodies and terminal labeling were observed in the medulla oblongata, peripheral ganglia of the glossopharyngeal and vagus nerves, and c ...	1996	8861108
effect of fluvoxamine on 5-hydroxytryptamine uptake, paroxetine binding sites and ketanserin binding sites in the japanese monkey brain and platelets, in vivo and in vitro.	we investigated the in vitro effects of fluvoxamine on 3h-paroxetine binding and 3h-monoamine uptake in monkey cerebral cortex in comparison with those of other antidepressants. fluvoxamine selectively inhibited 3h-5-hydroxytryptamine (5-ht) uptake and 3h-paroxetine binding. however, it did not alter 3h-norepinephrine or 3h-dopamine uptake. in addition, we examined the effects of chronic treatment with fluvoxamine (5 mg/kg per day, p.o.) on 5-ht uptake sites that bind 3h-paroxetine and 5-ht2 rec ...	1996	8886926
overlapping corticostriatal projections from the supplementary motor area and the primary motor cortex in the macaque monkey: an anterograde double labeling study.	the purpose of the present study was to determine if the cortical efferents from homologous body regions of the supplementary motor area (sma) and the primary motor cortex (mi) project to separate or to overlapping regions in the striatum. in order to investigate the dual corticostriatal projections, we employed an anterograde double labeling paradigm in which two tracers could be simultaneously detected in the same histological section. prior to the injections, the forelimb representation in th ...	1996	8889928
overlapping corticostriatal projections from the supplementary motor area and the primary motor cortex in the macaque monkey: an anterograde double labeling study.	the purpose of the present study was to determine if the cortical efferents from homologous body regions of the supplementary motor area (sma) and the primary motor cortex (mi) project to separate or to overlapping regions in the striatum. in order to investigate the dual corticostriatal projections, we employed an anterograde double labeling paradigm in which two tracers could be simultaneously detected in the same histological section. prior to the injections, the forelimb representation in th ...	1996	8889928
changing directions of forthcoming arm movements: neuronal activity in the presupplementary and supplementary motor area of monkey cerebral cortex.	1. to understand roles played by two cortical motor areas, the presupplementary motor area (pre-sma) and supplementary motor area (sma), in changing planned movements voluntarily, cellular activity was examined in two monkeys (macaca fuscata) trained to perform an arm-reaching task in which they were asked to press one of two target buttons (right or left) in three different task modes. 2. in the first mode (visual), monkeys were visually instructed to result and press either a right or left key ...	1996	8899607
effects of short-term treatment with mevalotin on platelet aggregation, fibrinolysis, peripheral serotonergic system and serum lipids in japanese monkeys.		1996	8928096
effects of short-term treatment with mevalotin on platelet aggregation, fibrinolysis, peripheral serotonergic system and serum lipids in japanese monkeys.		1996	8928096
molecular features of the tspy gene of gibbons and old world monkeys.	restriction pattern, chromosome localization and the sequence of the testis-specific gene, tspy, were investigated in the white-handed gibbon, agile gibbon, siamang, hamadryas baboon and japanese monkey. southern blot analysis showed the tspy gene to be male specific in the primates used and disclosed variability of restriction pattern in gibbons. fluorescence in situ hybridization demonstrated that the probe pptspy2372, biotinylated using polymerase chain reaction, is located as a slight signal ...	1996	8939361
molecular features of the tspy gene of gibbons and old world monkeys.	restriction pattern, chromosome localization and the sequence of the testis-specific gene, tspy, were investigated in the white-handed gibbon, agile gibbon, siamang, hamadryas baboon and japanese monkey. southern blot analysis showed the tspy gene to be male specific in the primates used and disclosed variability of restriction pattern in gibbons. fluorescence in situ hybridization demonstrated that the probe pptspy2372, biotinylated using polymerase chain reaction, is located as a slight signal ...	1996	8939361
prevention of human t cell lymphotropic virus type i infection in japanese macaques by passive immunization.	prophylaxis against human t cell lymphotropic virus type i (htlv-i) is of primary importance for the eradication of adult t cell leukemia and other diseases associated with this virus. hyperimmune globulin (h-igg) prepared from healthy blood donors with high antibody titers for htlv-i was evaluated for its prophylactic effect against htlv-i in japanese macaques (macaca fuscata). normal igg (n-igg) prepared from seronegative healthy blood donors was used as control. both preparations contained 50 ...	1996	8946939
survey for pneumocystis carinii infection of wild-born and laboratory-bred monkeys by indirect immunofluorescence and cyst-staining methods.	a serosurvey for pneumocystis carinii infection of laboratory-bred and wild-born monkeys was made by the indirect immunofluorescence method. the antibody titers of wild cynomolgus (macaca fascicularis) and japanese monkeys (macaca fuscata fuscata) to p. carinii (pc) were higher than those of laboratory-bred cynomolgus monkeys; 54.9% of the wild cynomolgus and 40% of japanese monkeys had antibody titers higher than 1:40, although only 9.4% of the laboratory-bred cynomolgus monkeys did so. pc cyst ...	1996	8950643
survey for pneumocystis carinii infection of wild-born and laboratory-bred monkeys by indirect immunofluorescence and cyst-staining methods.	a serosurvey for pneumocystis carinii infection of laboratory-bred and wild-born monkeys was made by the indirect immunofluorescence method. the antibody titers of wild cynomolgus (macaca fascicularis) and japanese monkeys (macaca fuscata fuscata) to p. carinii (pc) were higher than those of laboratory-bred cynomolgus monkeys; 54.9% of the wild cynomolgus and 40% of japanese monkeys had antibody titers higher than 1:40, although only 9.4% of the laboratory-bred cynomolgus monkeys did so. pc cyst ...	1996	8950643
stereoselectivity in bunitrolol 4-hydroxylation in liver microsomes from marmosets and japanese monkeys.	the stereoselectivity in 4-hydroxylation of bunitrolol (btl), a beta-adrenoreceptor blocking agent, was examined in liver microsomes from monkeys (marmosets and japanese monkeys) and compared with the results of human liver microsomes. the formation of (+)-4-oh-btl from (+)-btl from (+)-btl was significantly higher than that of (-)-4-oh-btl from (-)-btl in the liver microsomal fractions from the two kinds of monkeys. the 4-oh-btl-forming activity from racemic btl was significantly lower than fro ...	1996	8951158
stereoselectivity in bunitrolol 4-hydroxylation in liver microsomes from marmosets and japanese monkeys.	the stereoselectivity in 4-hydroxylation of bunitrolol (btl), a beta-adrenoreceptor blocking agent, was examined in liver microsomes from monkeys (marmosets and japanese monkeys) and compared with the results of human liver microsomes. the formation of (+)-4-oh-btl from (+)-btl from (+)-btl was significantly higher than that of (-)-4-oh-btl from (-)-btl in the liver microsomal fractions from the two kinds of monkeys. the 4-oh-btl-forming activity from racemic btl was significantly lower than fro ...	1996	8951158
quadrupedal locomotor movements in monkeys (m. fuscata) on a treadmill: kinematic analyses.	three adult japanese monkeys (m. fuscata: body weights 4.5-8.5 kg) were trained to walk quadrupedally on a surface of a moving treadmill (walking length and width: 150 cm and 60 cm, treadmill speed: 0.4-1.7 m s-1. at any different constant treadmill velocity, the monkeys exhibited a diagonal pattern of locomotor movements. side views of locomotor patterns were photographed (10 frames s-1 and videotaped (250 frames s-1. depictions of representative locomotor patterns and stick figures of forelimb ...	1996	8951840
quadrupedal locomotor movements in monkeys (m. fuscata) on a treadmill: kinematic analyses.	three adult japanese monkeys (m. fuscata: body weights 4.5-8.5 kg) were trained to walk quadrupedally on a surface of a moving treadmill (walking length and width: 150 cm and 60 cm, treadmill speed: 0.4-1.7 m s-1. at any different constant treadmill velocity, the monkeys exhibited a diagonal pattern of locomotor movements. side views of locomotor patterns were photographed (10 frames s-1 and videotaped (250 frames s-1. depictions of representative locomotor patterns and stick figures of forelimb ...	1996	8951840
distribution of muscle fibre types in the thoracic and lumbar epaxial muscles of japanese macaques (macaca fuscata).	histochemical properties are investigated in the thoracic and lumbar epaxial muscles of japanese macaques, macaca fuscata. whole transverse sections of the muscles were removed at the different levels of the thoracic and lumbar vertebrae and muscle fibre types were classified into type i and type ii fibres on the basis of their histochemical profiles. in the lumbar region the iliocostalis and longissimus muscles have many type ii fibres. in the thoracic region the iliocostalis muscle has more ty ...	1996	8953748
footfall patterns in the early development of the quadrupedal walking of japanese macaques.	the development of quadrupedal walking in infant japanese macaques (macaca fuscata) was studied on the basis of their footfall patterns. lateral views of the walking of 5 monkeys were taken by a video-camera and the timing of touchdown and liftoff was recorded. the total number of trials was 435. the change of footfall patterns during development was complicated. four stages could be discerned, as in behavioural studies. in the first stage, there was a wide variation. the dominant patterns were ...	1996	8953754
mobility of hindlimb joints in japanese macaques (macaca fuscata) as influenced by biarticular musculature.	joint mobility is a critical issue in the analysis of locomotor adaptation. here we have attempted precise measurements of the range of extension/flexion of the hip, knee, and ankle joints of japanese macaques by using fresh cadavers and devising an effective method to fixate the proximal segment. severance of biarticular muscles revealed restrictions in mobility of as much as 10-25% caused by these muscles. however, incidences of an incomplete removal of the restriction through severance sugges ...	1996	8953758
ecabet sodium eradicates helicobacter pylori infection in gastric ulcer patients.	ecabet sodium (ecabet), a new agent that has protective effects on the gastric mucosa has anti-helicobacter pylori effects, binding with urease to inhibit h. pylori activity, and causing the bacterial to become non-viable. ecabet monotherapy eradicates h. pylori infection in japanese monkeys. we investigated a new regimen that included ecabet to eradicate h. pylori infection in gastric ulcer patients. fifty-five h. pylori-positive patients with gastric ulcer were randomly assigned to one of two ...	1996	8959522
ecabet sodium eradicates helicobacter pylori infection in gastric ulcer patients.	ecabet sodium (ecabet), a new agent that has protective effects on the gastric mucosa has anti-helicobacter pylori effects, binding with urease to inhibit h. pylori activity, and causing the bacterial to become non-viable. ecabet monotherapy eradicates h. pylori infection in japanese monkeys. we investigated a new regimen that included ecabet to eradicate h. pylori infection in gastric ulcer patients. fifty-five h. pylori-positive patients with gastric ulcer were randomly assigned to one of two ...	1996	8959522
direct projections from the medial vestibular nucleus to the posterior hypothalamic area in the monkey (macaca fuscata).	direct projections from the medial vestibular nucleus to the posterior hypothalamic area was found in the macaque monkey by the anterograde and the retrograde tract-tracing methods. after injection of biotinylated dextran amine (bda) into the ventrolateral part of the medial vestibular nucleus, anterogradely labeled axon terminals were seen bilaterally in the posterior hypothalamic area. after injection of wheat germ agglutinin-conjugated horseradish peroxidase (wga-hrp) into the posterior hypot ...	1996	8971814
demonstration of a new dopamine-containing cell group in the primate rostral telencephalon.	the presence of dopaminergic neurons in the rostral forebrain has long been uncertain though the existence of tyrosine-hydroxylase (th)-containing cells has been known in the region. using an antibody to dopamine (da), we demonstrated neurons immunoreactive (ir) to da in the rostroventral striatum of the japanese monkey (macaca fuscata). the da-ir cells were found at the ventral margin of the rostral part of the caudate nucleus, at the ventral margin of the rostral part of the nucleus accumbens, ...	1996	8977151
context dependent discharge characteristics of saccade-related purkinje cells in the cerebellar hemispheres of the monkey.	in the previous paper (mano et al, 1991), we reported the discharge patterns of saccade-related purkinje cells during visually guided saccade task, which were recorded from posterior cerebellar hemisphere, the crus iia. in the present study, we analysed these p-cell's simple spike activity during the spontaneous saccade in inter-trial intervals (iti) of visually guided saccade task, comparing with the activity during the visually guided saccade. we found that the modulation of simple spike disch ...	1996	8979847
context dependent discharge characteristics of saccade-related purkinje cells in the cerebellar hemispheres of the monkey.	in the previous paper (mano et al, 1991), we reported the discharge patterns of saccade-related purkinje cells during visually guided saccade task, which were recorded from posterior cerebellar hemisphere, the crus iia. in the present study, we analysed these p-cell's simple spike activity during the spontaneous saccade in inter-trial intervals (iti) of visually guided saccade task, comparing with the activity during the visually guided saccade. we found that the modulation of simple spike disch ...	1996	8979847
responses of monkeys with pollinosis to two major allergens of japanese cedar pollen.	we examined the responses of two japanese monkeys with pollinosis to two major allergens (cry j 1 and cry j 2) of japanese cedar pollen. the two monkeys (a and b) had specific ige antibodies to the allergens and showed a strong positive reaction to both of them in the intradermal test. in the histamine release test with peripheral blood mononuclear cells (pbmc), monkey a showed a typical pattern similar to that seen in human patients, while monkey b released a low level of histamine. the prolife ...	1997	8980469
responses of monkeys with pollinosis to two major allergens of japanese cedar pollen.	we examined the responses of two japanese monkeys with pollinosis to two major allergens (cry j 1 and cry j 2) of japanese cedar pollen. the two monkeys (a and b) had specific ige antibodies to the allergens and showed a strong positive reaction to both of them in the intradermal test. in the histamine release test with peripheral blood mononuclear cells (pbmc), monkey a showed a typical pattern similar to that seen in human patients, while monkey b released a low level of histamine. the prolife ...	1997	8980469
helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in japanese monkeys.	to clarify the relationship between helicobacter pylori and the healing of gastric ulcers, we investigated the healing of acetic acid-induced gastric ulcers in the antral mucosa of japanese monkeys (n = 5) infected with h. pylori and in control monkeys without h. pylori infection (n = 6). using h. pylori-infected japanese monkeys as an experimental model, gastric ulcers were induced endoscopically with acetic acid. healing of ulcers and factors that influenced healing were studied. continuous co ...	1996	8985837
helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in japanese monkeys.	to clarify the relationship between helicobacter pylori and the healing of gastric ulcers, we investigated the healing of acetic acid-induced gastric ulcers in the antral mucosa of japanese monkeys (n = 5) infected with h. pylori and in control monkeys without h. pylori infection (n = 6). using h. pylori-infected japanese monkeys as an experimental model, gastric ulcers were induced endoscopically with acetic acid. healing of ulcers and factors that influenced healing were studied. continuous co ...	1996	8985837
influences of nasal respiratory obstruction on craniofacial growth in young macaca fuscata monkeys.	this study was conducted to investigate the influences of artificial nasal respiratory obstruction on craniofacial growth in young macaca fuscata monkeys. eleven monkeys were used; seven monkeys served as the experimental animals and the remaining four as the control animals. further, the experimental animals were divided into light and heavy obstruction groups. nasal respiratory obstruction was created by injecting dental impression material into the nasopharyngeal region. nasal respiratory fun ...	1997	9009922
double gallbladder of swine.	in research on the reduplication of the pig gallbladder, a total of 297,531 swine from 130 breeders were surveyed at a slaughter house (ozu health center, ehime prefecture, japan) between october 1993 and december 1995. the swine were 6-7 months old and their body weights ranged from 95 to 120 kg. twenty-nine swine were found to have reduplication of the gallbladder. of these 19 were females, nine were males and the sex of one was not identified. the second sac was smaller than main one. eleven ...	1996	9038007
in vitro fertilization of follicular oocytes by frozen-thawed spermatozoa in japanese monkeys (macaca fuscata).	we report the cryopreservation of epididymal spermatozoa and in vitro fertilization for japanese monkeys (macaca fuscata). ovarian stimulation of seven monkeys was studied by the administration of equine chorionic gonadotrophin (ecg) and human chorionic gonadotrophin (hcg) during the nonbreeding season, after which oocytes were collected from ovarian follicles. the oocytes were subjected to in vitro fertilization by the frozen-thawed epididymal spermatozoa collected from a male monkey during the ...	1997	9051648
in vitro fertilization of follicular oocytes by frozen-thawed spermatozoa in japanese monkeys (macaca fuscata).	we report the cryopreservation of epididymal spermatozoa and in vitro fertilization for japanese monkeys (macaca fuscata). ovarian stimulation of seven monkeys was studied by the administration of equine chorionic gonadotrophin (ecg) and human chorionic gonadotrophin (hcg) during the nonbreeding season, after which oocytes were collected from ovarian follicles. the oocytes were subjected to in vitro fertilization by the frozen-thawed epididymal spermatozoa collected from a male monkey during the ...	1997	9051648
sex differences in mortality of japanese macaques: twenty-one years of data from the arashiyama west population.	theorists argue that mortality in male mammals should be higher than that of females, and many studies of primates followed across the life course have found this to be the case. this study examines mortality patterns in the rapidly expanding arashiyama west (texas) population of japanese macaques (macaca fuscata) and finds that males have a significantly lower median survival age (12.2 years) in comparison to females (20.5 years). males and females are born in equal proportions, but by adulthoo ...	1997	9066898
differential kinship effect on reconciliation in three species of macaques (macaca fascicularis, m. fuscata, and m. sylvanus).	macaque societies are typically characterized by despotic dominance styles and strong bonds between related individuals. interspecies variation in dominance style, however, has been recently documented. this study investigated whether kinship effects on social interactions vary depending on the species dominance style. reconciliation was chosen as as a measure of relationship quality between group members. groups of japanese (macaca fuscata) and long-tailed (m. fascicularis) macaques were select ...	1997	9090139
determinants of the dramatic seasonal changes in the intake of energy and protein by japanese monkeys in a cool temperate forest.	daily intake of gross energy (dgei) and protein (dgpi) of japanese monkeys in a cool temperature forest were investigated in different four seasons. as a result, dramatic seasonal differences in dgei and dgpi were found: dgei and dgpi in winter were significantly lower than those in spring and autumn, being only about 17-42% of those in the two seasons. dgei and dgpi in summer were also lower than those in autumn and spring, being only about 29-52% of those in the two latter seasons. seasonal co ...	1997	9093692
determinants of the dramatic seasonal changes in the intake of energy and protein by japanese monkeys in a cool temperate forest.	daily intake of gross energy (dgei) and protein (dgpi) of japanese monkeys in a cool temperature forest were investigated in different four seasons. as a result, dramatic seasonal differences in dgei and dgpi were found: dgei and dgpi in winter were significantly lower than those in spring and autumn, being only about 17-42% of those in the two seasons. dgei and dgpi in summer were also lower than those in autumn and spring, being only about 29-52% of those in the two latter seasons. seasonal co ...	1997	9093692
auditory behavioral thresholds for japanese macaques using insert earphones.	the goal of this study was to measure behavioral auditory thresholds in four japanese macaques. animals were trained using food as a reward in an operant reinforcement paradigm. stimuli were 1-s sinusoids with 10-ms rise/fall times delivered through insert earphones (etymotic er-1) having expandable foam eartips. the animals generally produced threshold contours similar in shape to those reported for other macaques species, except that the low-frequency thresholds may have been slightly higher i ...	1997	9093695
intraarterial infusion of papaverine in experimental cerebral vasospasm.	to determine the effectiveness of intraarterial infusion of papaverine hydrochloride (ppv) in an experimental model of cerebral vasospasm and to measure the mean blood flow velocity of the middle cerebral artery (mca).	1997	9111660
intraarterial infusion of papaverine in experimental cerebral vasospasm.	to determine the effectiveness of intraarterial infusion of papaverine hydrochloride (ppv) in an experimental model of cerebral vasospasm and to measure the mean blood flow velocity of the middle cerebral artery (mca).	1997	9111660
diverse inotropic effects of 5-hydroxytryptamine in heart muscles of various mammalian species.	the inotropic effects of 5-hydroxytryptamine (5-ht) on mammalian heart muscles were investigated. 5-ht (10(-8)-10(-3)m) produced increases in the contractile tension of atrial and ventricular muscles isolated from guinea pigs, japanese monkeys, and humans, but not in rat heart preparations. the maximum percent increase of contraction was largest in guinea pig ventricular muscles (142.0 percent), followed by monkey atrium (86.3 percent), human atrium (71.7 percent), guinea pig atrium (48.7 percen ...	1996	9119800
diverse inotropic effects of 5-hydroxytryptamine in heart muscles of various mammalian species.	the inotropic effects of 5-hydroxytryptamine (5-ht) on mammalian heart muscles were investigated. 5-ht (10(-8)-10(-3)m) produced increases in the contractile tension of atrial and ventricular muscles isolated from guinea pigs, japanese monkeys, and humans, but not in rat heart preparations. the maximum percent increase of contraction was largest in guinea pig ventricular muscles (142.0 percent), followed by monkey atrium (86.3 percent), human atrium (71.7 percent), guinea pig atrium (48.7 percen ...	1996	9119800
location of efferent terminals of the primate flocculus and ventral paraflocculus revealed by anterograde axonal transport methods.	efferents of the flocculus (fl) and ventral paraflocculus (vp) were examined in seven anesthetized macaca fuscata by anterograde axonal transport method using wheat germ agglutinin-conjugated horseradish peroxidase or phaseolus vulgaris leucoagglutinin. several major foci of axon terminals were found in the vestibular nuclear complex and cerebellar nuclei. a difference was seen in the location of efferent terminals between the fl and vp. when the tracer covered the fl, labeled axon terminals wer ...	1997	9129184
somatostatin and brain-derived neurotrophic factor mrna expression in the primate brain: decreased levels of mrnas during aging.	the expression of the genes for somatostatin (srif) and brain-derived neurotrophic factor (bdnf) was investigated in the central nervous system (cns) of the macaque monkey (macaca fuscata fuscata). using northern blot analysis, one srif mrna transcript, 0.65 kb, and two bdnf mrna transcripts, 1.6 and 4.0 kb in length, were detected in the monkey brain tissues. during the aging process (2 years, 10 years, and > 30 years), the ratio of srif mrna/glyceraldehyde-3 phosphate dehydrogenase (g3pdh) mrn ...	1997	9138728
geographic distribution of gongylonema pulchrum and gongylonema macrogubernaculum from macaca fuscata in japan.	after a first report on the gullet nematode, gongylonema pulchrum molin, 1857, being found in the japanese macaque, macaca fuscata, in kyushu, japan, the geographic distribution of the parasite, a causative agent of gongylonemiasis in cattle and man, was examined in 181 monkeys transferred to the japan. monkey centre from 23 sites in japan, including yaku-shima (island). yaku-shima is included in the world natural heritage list of the united nations for its subtropical forests, which have an unu ...	1994	9140479
[visually-guided discrimination and preference of sexuality in female macaque monkeys].	visual information about face and body including facial expression and bodily behavioral patterns has been known to play an important role in social and emotional communication in monkeys. its involvement in sexual activity has also been demonstrated in male monkeys but it is poorly understood in female monkeys. in the present study, visually-guided discrimination and preference of sexuality were investigated in female macaque monkeys performing operant bar-press tasks in an experimental cage wh ...	1997	9154714
[visually-guided discrimination and preference of sexuality in female macaque monkeys].	visual information about face and body including facial expression and bodily behavioral patterns has been known to play an important role in social and emotional communication in monkeys. its involvement in sexual activity has also been demonstrated in male monkeys but it is poorly understood in female monkeys. in the present study, visually-guided discrimination and preference of sexuality were investigated in female macaque monkeys performing operant bar-press tasks in an experimental cage wh ...	1997	9154714
the locus coeruleus of the japanese monkey (macaca fuscata) does not express mu-opioid receptor-like immunoreactivity.	it is well known that locus coeruleus (lc) of the rat shows intense mu-opioid receptor-like immunoreactivity (mor-li). in the course of our study on the distribution of mor-li in the brain of the japanese monkey (macaca fuscata), however, no mor-li was found in the lc although the distribution pattern of mor-li in other regions of the lower brainstem of the monkey was essentially the same as that observed in the rat. it was also found that immunoreactivity for met-enkephalin, the most potent end ...	1997	9175900
distribution of endothelin and endothelin-a receptor in the lacrimal glands of the monkey (macaca fuscata).	endothelin (et) is well known to be a potent vasoconstrictor peptide with autocrine and paracrine function. it has been documented that et is also present in non-muscle tissues. the distribution of et and et-a receptor (et-ar) in the monkey lacrimal gland was investigated by immunohistochemistry. three adult male monkeys (macaca fuscata) were perfused with a fixative. the lacrimal glands were then dissected and sectioned. using rabbit anti-et and anti-et-ar antibodies, the immunohistochemical pr ...	1997	9176045
growth pattern of the maxillary sinus in the japanese macaque (macaca fuscata): reflections on the structural role of the paranasal sinuses.	to investigate the claim that the primate paranasal sinuses possess not a functional but a structural role associated with the skull architecture (blaney, 1990), the relationship between the maxillary sinus and the skull architecture was studied ontogenetically in 30 skulls of male and female japanese macaques (macaca fuscata). coronal ct scan series and computerised 3-dimensional images served to evaluate the maxillary sinus. the definitive hemispherical shape of the sinus was already achieved ...	1997	9183677
differences of the primate flocculus and ventral paraflocculus in the mossy and climbing fiber input organization.	potential sources of cerebellar cortical afferent fibers were identified in the vestibular ganglion, medulla oblongata, pons, and cerebellar nucleus of seven anesthetized macaca fuscata after local injections of wheat germ agglutinin-conjugated horseradish peroxidase or fast blue into the flocculus (fl) or ventral paraflocculus (vp). there were differences in the sources of mossy fibers to the fl and vp. labeled neurons, after injections into the fl, were located mainly in the ipsilateral vestib ...	1997	9184995
birth rate and mortality rate of infants with congenital malformations of the limbs in the awajishima free-ranging group of japanese monkeys (macaca fuscata).	the birth rate and mortality rate of infants with congenital malformations of the limbs were examined in the awajishima free-ranging group of japanese macaques (macaca fuscata). of the 606 infants born between 1978 and 1995, 86 (14.2%) were malformed. the male-female ratio did not differ between malformed and normal infants. most kin-groups included females who gave birth to malformed infants at least once. the mortality rate within the first year after birth for malformed infants (28.2%) was si ...	1997	9209587
birth rate and mortality rate of infants with congenital malformations of the limbs in the awajishima free-ranging group of japanese monkeys (macaca fuscata).	the birth rate and mortality rate of infants with congenital malformations of the limbs were examined in the awajishima free-ranging group of japanese macaques (macaca fuscata). of the 606 infants born between 1978 and 1995, 86 (14.2%) were malformed. the male-female ratio did not differ between malformed and normal infants. most kin-groups included females who gave birth to malformed infants at least once. the mortality rate within the first year after birth for malformed infants (28.2%) was si ...	1997	9209587
synaptic specializations associated with the outer hair cells of the japanese macaque.	across species the innervation of outer hair cells (ohcs) shows a remarkable similarity. there are, however, notable differences in fine structure. the present work describes the normal synaptic morphology of ohcs in the japanese macaque (macaca fuscata), as determined by examination of serial sections with transmission electron microscopy. the nerve endings at the base of ohcs were divided primarily into two groups: vesiculated (efferent) and non-vesiculated (afferent). in addition, we found su ...	1997	9213121
epitope specificity of ige antibodies to a major allergen (cry j 1) of japanese cedar pollen in sera of humans and monkeys with pollinosis.	japanese cedar (cryptomeria japonica) pollinosis has been reported to occur naturally in japanese monkeys (macaca fuscata) as well as humans. using monoclonal antibodies (mab) specific to cry j 1, a major allergen in japanese cedar pollen, we identified five independent epitopes (ep-1 to ep-5) on the molecule. the epitopes recognized by ige antibodies in the sera of humans and monkeys with the pollinosis were analysed by an ige enzyme-linked immunosorbent assay inhibition method with these mab. ...	1997	9227312
epitope specificity of ige antibodies to a major allergen (cry j 1) of japanese cedar pollen in sera of humans and monkeys with pollinosis.	japanese cedar (cryptomeria japonica) pollinosis has been reported to occur naturally in japanese monkeys (macaca fuscata) as well as humans. using monoclonal antibodies (mab) specific to cry j 1, a major allergen in japanese cedar pollen, we identified five independent epitopes (ep-1 to ep-5) on the molecule. the epitopes recognized by ige antibodies in the sera of humans and monkeys with the pollinosis were analysed by an ige enzyme-linked immunosorbent assay inhibition method with these mab. ...	1997	9227312
inhibitory effect of monatepil maleate on acyl-coa:cholesterol acyltransferase activity in the liver of cholesterol-fed japanese monkeys.	we have previously demonstrated that monatepil maleate, aj-2615, a new calcium antagonist endowed with alpha1-adrenoceptor blocking property, has antiatherosclerotic and plasma lipid-lowering effects in japanese monkeys fed on a cholesterol-rich diet. to clarify the mechanisms on plasma lipid-lowering action, we investigated the effect of monatepil maleate in these monkeys on hepatic acyl-coa:cholesterol acyltransferase (acat) activity. both acat activity and esterified cholesterol content in th ...	1997	9234833
inhibitory effect of monatepil maleate on acyl-coa:cholesterol acyltransferase activity in the liver of cholesterol-fed japanese monkeys.	we have previously demonstrated that monatepil maleate, aj-2615, a new calcium antagonist endowed with alpha1-adrenoceptor blocking property, has antiatherosclerotic and plasma lipid-lowering effects in japanese monkeys fed on a cholesterol-rich diet. to clarify the mechanisms on plasma lipid-lowering action, we investigated the effect of monatepil maleate in these monkeys on hepatic acyl-coa:cholesterol acyltransferase (acat) activity. both acat activity and esterified cholesterol content in th ...	1997	9234833
dopaminergic innervation of the monkey caudal nucleus accumbens.	previous studies have shown that the monkey (macaca fuscata) caudal nucleus accumbens is neurochemically subdivided into three subdivisions, the medial, dorsolateral, and ventral subdivisions. in this study, dopaminergic innervation of these three subdivisions was studied in detail for the first time by light microscopic immunocytochemistry using a monoclonal antibody against dopamine. the patterns of dopamine fiber distribution were heterogeneous even within each subdivision. the medial subdivi ...	1997	9241445
fine structure of crest synapses in the locus coeruleus of the japanese macaque (macaca fuscata), with special reference to noradrenergic neurons.	the crest synapse and its related structures in the locus coeruleus (lc) of the japanese monkey, macaca fuscata, were electronmicroscopically studied using noradrenaline (na) immunohistochemistry and tannic acid fixation. about 20% to 25% of the noradrenergic input to the lc terminated at noradrenergic neurons. about 1/3 of these na-na connections formed crest synapses, although conversely, na-immunoreactive (ir) terminals were found in 10% of all terminals forming crest synapses. the crests sho ...	1997	9251296
cerebello-cerebral projections onto the ventral part of the frontal cortex of the macaque monkey.	the cerebellar projections to the ventral part of the frontal cortex were investigated in the japanese monkey (macaca fuscata). in anesthetized monkeys, stimulation of either the lateral or interposed cerebellar nucleus evoked marked surface-negative and depth-positive potentials in the face motor area (mf) and the upper part of the ventral premotor area (pmv) on the contralateral side; responses were hardly recorded in the lower part of pmv including the areas related to the laryngeal movements ...	1997	9259474
parity-related differences in suckling behavior and nipple preference among free-ranging japanese macaques.	suckling behavior of primiparae in free-ranging japanese macaques (macaca fuscata) was compared with that of multiparae at jigokudani monkey park, the shiga heights, nagano prefecture, japan, from april 1984 to 1994. the estimated rates of milk secretion in a single preferred nipple among primiparae were lower than those among multiparae from birth to 5 months of age. milk secretion capabilities of primiparous mothers, hence, appear to be inferior to those of multiparous mothers. in nutritive su ...	1997	9261514
dna vaccination followed by macromolecular multicomponent peptide vaccination against hiv-1 induces strong antigen-specific immunity.	the induction of a strong and long-lasting immunity characterized by both a humoral and cell-mediated immune (cmi) response is one of the most important considerations in developing an effective hiv vaccine. in previous studies, we have independently developed both dna vaccine and macromolecular multicomponent peptide vaccine (vc1) candidates. in the present study, we attempted to optimize the vaccination protocol using mice, guinea pigs, rabbits and macaca fuscata monkeys. repeated vaccination ...	1997	9269046
perceptual salience of acoustic features of japanese monkey coo calls.	smooth early high (seh) and smooth late high (slh) coo calls differ in the temporal location of a frequency inflection and are generally used in different situations. coo quality is also influenced by additional features, such as relative harmonic level, which may have communicative significance. the authors used multidimensional scaling to analyze the perceptual similarity of seh and slh coos. neither the temporal position of the frequency inflection nor caller identity could explain the coo gr ...	1997	9286095
sexual selection in japanese macaques i: female mate choice or male sexual coercion?	mate choice is defined as a behavioural pattern in one sex which increases the probability of fertile matings with certain members of the opposite sex. the chosen sex may use force, however, to coerce matings from reluctant members of the choosing sex. in a confined group of japanese macaques, macaca fuscata fuscatahoused at the primate research institute of kyoto university, japan, behavioural and endocrine data were combined to assess the validity of several mate-choice behaviours and the pote ...	1997	9299056
sexual selection in japanese macaques ii: female mate choice and male-male competition	mating and reproductive outcomes are the product of the potentially conficting strategies of breeding males and females. in a captive group of japanese macaques, macaca fuscata fuscatabehavioural, endocrine and genetic data were combined to assess the independent effects of male-male competition and female mate choice on mating and reproductive success. males were ranked by social dominance and by their attractivity to females. computer simulation and logistic regression analyses showed that mal ...	1997	9299057
rapid decalcification of temporal bones with preservation of ultrastructure.	decalcification of temporal bones, especially from primates, has routinely required long periods of time and has been a major deterrent to many types of morphological studies. in this investigation, temporal bones from the monkey, macaca fuscata, were decalcified with ethylene diamine tetraacetic acid (edta) in a microwave oven. to isolate effects of microwaves on decalcification, tissue was fixed and embedded using routine methods; only decalcification was carried out in the microwave oven. the ...	1997	9307313
long-term cryopreserved allogeneic nervous and vascular tissue transfers in monkeys.	four adult japanese monkeys were used. donor tissues were harvested from the radial artery, saphenous vein and median nerve, 10 cm in length, and cryopreserved at -196 degrees c in a stepwise manner for long-term preservation for more than 6 months. after rapid thawing of the tissue, the allogeneic tissue transfer was performed of the radial artery to the radial artery, the saphenous vein to the ulnar artery and the median nerve to the median nerve between male and female monkeys. after one year ...	1996	9308713
long-term cryopreserved allogeneic nervous and vascular tissue transfers in monkeys.	four adult japanese monkeys were used. donor tissues were harvested from the radial artery, saphenous vein and median nerve, 10 cm in length, and cryopreserved at -196 degrees c in a stepwise manner for long-term preservation for more than 6 months. after rapid thawing of the tissue, the allogeneic tissue transfer was performed of the radial artery to the radial artery, the saphenous vein to the ulnar artery and the median nerve to the median nerve between male and female monkeys. after one year ...	1996	9308713
layer-specific differential regulation of transcription factors zif268 and jun-d in visual cortex v1 and v2 of macaque monkeys.	to investigate intracellular mechanisms of cortical layer-specific gene regulation, we quantitatively examined the expression of two transcription factors, zif268 and jund, and compared their expression levels in each layer of the primary visual cortex (vi) and visual area 2 (v2) of macaque monkeys (macaca fuscata). the brain sections were immunohistochemically stained for determination of the percentage of zif268- or jund-expressing neurons in the total neuronal population. we found area- and l ...	1997	9316018
stability of ocular counterrolling and listing's plane during static roll-tilts.	to investigate whether habituation occurs in ocular counterrolling (ocr), how stable shifted listing's plane is, and what effects visual stimulation and alertness exert on the ocr and on listing's plane.	1997	9331274
observation of periparturitional behaviour in wild yakushima macaques (macaca fuscata yakui).		1997	9375368
enzyme-histochemical demonstration of the intramural lymphatic network in the monkey jejunum.	the structural organization of the intramural lymphatic networks in the jejunum of the japanese monkey (macaca fuscata) was studied by an enzyme-histochemical method using whole-mount preparations of tissue layers. a distinction between the lymphatics and the blood vessels was made by light microscopy using 5'-nucleotidase (5'-nase)-alkaline phosphatase (alpase) double staining. in each tissue specimen, the reaction product for 5'-nase activity was localized in the lymphatic vessels, whereas tha ...	1997	9376169
a multidimensional scaling analysis of vowel discrimination in humans and monkeys.	multidimensional scaling (mds) was used to compare perceptual maps for 10 synthetic english vowels in humans and old world monkeys (macaca fuscata and cercopithecus albogularis). subjects discriminated among the vowels using a repeating background procedure, and reaction times were submitted to an mds analysis to derive measures of perceive similarity. the dimensions that emerged related to the frequencies of the first (f1), second (f2), and third (f3) formants. human data indicated a good match ...	1997	9401456
nucleotide sequence of cdna and the gene expression of testis-specific protein y in the japanese monkey.	we cloned the cdna for japanese monkey testis-specific protein y (tspy). the cdna contained an open reading frame of 246 amino acids. this coding fragment shared 89% nucleotide sequence identity and 81% amino acid sequence identity with the homologous fragment of previously isolated human tspy cdna. monkey tspy was assumed to be a molecular mass of 28 kda and an isoelectric point of ph 5.35. this protein was hydrophilic and contained an arg and lys-rich region which was a potential dna binding s ...	1997	9401465
seasonal variation in the feeding behavior and diet of japanese macaques (macaca fuscata yakui) in lowland forest of yakushima.	the feeding behavior of the southern subspecies of japanese macaque (macaca fuscata yakui) was studied over a period of 18 months in warm temperate broad-leaved forest on the island of yakushima, japan. focal animal data were collected for the eight adults in the troop. over a full annual cycle, 35.0% of foraging on identified foods was on leaves and shoots, 30.2% on fleshy fruit, 13.2% on seeds, and 5.5% on flowers. invertebrates and other animal matter accounted for 10.3% of foraging and fungi ...	1997	9403095
hypervariable microsatellite loci in the japanese macaque (macaca fuscata) conserved in related species.	we describe seven polymorphic microsatellites isolated from a japanese macaque (macaca fuscata) genomic library selected for (gt)n content. the primer sets amplified from four to 11 different alleles in a sample of 14 japanese macaques from nine different sites along the central and southern distribution of the species. these heterologous primers also detected variability in four other cercopithecine species.	1997	9403100
carrying and washing of grass roots by free-ranging japanese macaques at katsuyama.		1998	9429314
localization of lewisx, sialyl-lewisx and alpha-galactosyl epitopes on glycosphingolipids in lens tissues.	mammalian lens contains several neutral and acidic glycosphingolipids, the core structures of which are ganglio-, neolacto-, globo-, and isoglobo-series sugar chains. old world monkey lens shows glycosphingolipid compositions similar to those of human cataractous lens, in particular the presence of lewisxand sialyl-lewisxepitopes and the absence of alpha-galactosyl epitope. dog and pig lenses contain globotriaosylceramide and the sialyl-lewisxcontaining neolactotetraosylceramide, respectively, w ...	1998	9451018
organization of choline acetyltransferase-containing structures in the cranial nerve motor nuclei and spinal cord of the monkey.	cholinergic structures in the cranial nerve motor nuclei and ventral and lateral horns of the spinal cord of the monkey, macaca fuscata, were investigated immunohistochemically with a monoclonal antibody against monkey choline acetyltransferase (chat). chat-immunoreactive perikarya and dendrites were present in the oculomotor, trochlear, abducent, trigeminal motor, facial and hypoglossal nuclei, nucleus of edinger-westphal, nucleus ambiguus, dorsal nucleus of the vagus, lamina ix of the cervical ...	1998	9473607
long-term sequelae of experimental gastritis with helicobacter pylori: a 5-year follow-up study.	to investigate the long-term effects of helicobacter pylori gastritis on the gastric mucosa, 13 wild japanese monkeys (six h. pylori-infected and seven controls) were monitored for 5 years. colonization with h. pylori, the presence of macroscopic and histological gastritis, pyloric glandular height, and epithelial cell kinetics were investigated, using ki-67 immunostaining in the gastric mucosa. in the infected group, persistent colonization with h. pylori was demonstrated by culture and histopa ...	1997	9479621
long-term sequelae of experimental gastritis with helicobacter pylori: a 5-year follow-up study.	to investigate the long-term effects of helicobacter pylori gastritis on the gastric mucosa, 13 wild japanese monkeys (six h. pylori-infected and seven controls) were monitored for 5 years. colonization with h. pylori, the presence of macroscopic and histological gastritis, pyloric glandular height, and epithelial cell kinetics were investigated, using ki-67 immunostaining in the gastric mucosa. in the infected group, persistent colonization with h. pylori was demonstrated by culture and histopa ...	1997	9479621
representation of objective similarity among three-dimensional shapes in the monkey.	humans have been recently shown to represent parameterized three-dimensional objects in a manner that preserves relative similarities (as measured by parameter-space distances) among the objects (cutzu and edelman 1996). we show that the representation of objects in the monkey visual system is similarly faithful to the parametric variation built into the stimulus set. a monkey (macaca fuscata) performed a delayed matching-to-sample task with 28 images (4 views x 7 objects). stimuli in each of th ...	1998	9485583
matching of acoustic features during the vocal exchange of coo calls by japanese macaques	a central issue in studies of vocalizations of non-human primates is the extent of their plasticity. japanese macaques, macaca fuscata, frequently utter coo calls and exchange these calls with other group members to maintain contact vocally. i conducted a playback experiment to examine whether monkeys that respond vocally match the acoustic features of their reply to those of the calls they have heard. six to eight stimulus calls with different acoustic properties in terms of fundamental frequen ...	1998	9514664
dopamine synthesizing enzymes in paraventricular hypothalamic neurons of the human and monkey (macaca fuscata).	using immunohistochemistry, we demonstrated that paraventricular hypothalamic neurons immunoreactive for tyrosine hydroxylase (th) were not immunopositive for the second step catecholamine synthesizing enzyme l-amino acid decarboxylase (aadc) in the human and monkey macaca fuscata. in the latter species, they were not immunoreactive for dopamine. it is most likely that primate paraventricular th-containing neurons do not synthesize dopamine.	1998	9535098
basement membrane-like structures occurring on the surface of dental papilla mesenchymal cells during odontogenesis in the monkey macaca fuscata.	the aim of this study was to examine the nature of a basement membrane-like structure occurring along the surface of dental papilla cells during odontogenesis. the tooth germs of japanese macaques (macaca fuscata) were prepared for both ultrastructural and immunohistochemical studies. characteristic discrete structures which resembled basement membranes were observed along the surface of the dental papilla cells, preodontoblasts, and also of the odontoblasts. immunoperoxidase staining showed tha ...	1998	9541214
adoption and social interactions between a mother and 'twin' offspring in macaca fuscata.		1998	9543733
a novel junction-like membrane complex in the optic nerve astrocyte of the japanese macaque with a possible relation to a potassium ion channel.	a new type of junction-like membrane complex (jmc) was detected between adjacent astrocytes in the optic nerve of japanese macaque (macaca fuscata). this membrane complex morphologically resembled a cell junction, but a possible role for potassium ion channels could not be denied based on freeze-fracture replica observation. we attempted to determine the chemical nature and function of the novel jmc.	1998	9566537
fiber type composition of abdominal muscles in japanese macaques (macaca fuscata).	the muscle fiber composition and cross-sectional area of muscle fiber types were investigated histochemically in the abdominal muscles (rectus abdominis muscle, obliquus externus abdominis muscle, obliquus internus abdominis muscle and transversus abdominis muscle) of three japanese macaques (macaca fuscata). muscle fibers were classified into three fiber types (type i, ii a and ii b) by myosin atpase activity and succinate dehydrogenase activity. each abdominal muscle in japanese macaques conta ...	1998	9584511
repair of bone defect in primate mandible using a bone morphogenetic protein (bmp)-hydroxyapatite-collagen composite.	the purpose of this study was to evaluate a hydroxyapatite (ha)-collagen (col)-bone morphogenetic protein (bmp) composite as an osteoinductive bone substitute. partially-purified bmp from bovine bone was mechanically mixed with highly purified type i collagen from calf dermis and then subsequently mixed with pure synthetic hydroxyapatite granules or block. the ha-col-bmp composite, or the ha-col composite as a control, was implanted in a surgically-induced mandible bone defect (6 x 7 x 10 mm) in ...	1997	9608283
tandem duplication of nucleolus organizer region (nor) in the japanese macaque, macaca fuscata fuscata.	during exploration of chromosome polymorphisms in japanese macaques, a heteromorphic polymorphism was found in a population in the zigokudani monkey park. the population consisted of three troops (social units). of 36 monkeys examined, five females showed heterozygotic 'marker' chromosome (chromosome 9). the polymorphism was a tandem duplication of the nucleolus organizer region (nor) of the short arm of chromosome 9, which was found for the first time in the genus macaca. fish and fibre-fish us ...	1998	9609662
continuity of affiliative relationships among infants and juveniles in a free-ranging group of japanese monkeys (macaca fuscata).	5 infants were observed during the first 13 mo. after birth in a free-ranging group of japanese monkeys (macaca fuscata) to examine whether they maintained relatively frequent affiliative relationships with particular immature individuals. the number of immature affiliative partners rapidly increased from the first 3-mo. period after birth to the second 4-mo. period after birth, and the infants thereafter maintained affiliative relationships with particular individuals, mostly same-aged infants, ...	1998	9621749