Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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[preparation of polyelectrolyte microcapsules containing ferrosoferric oxide nanoparticles]. | in this study, polyelectrolyte microcapsules have been fabricated by biocompatible ferrosoferric oxide nanoparticles (fe3o4 nps) and poly allyamine hydrochloride (pah) using layer by layer assembly technique. the fe3o4 nps were prepared by chemical co-precipitation, and characterized by transmission electron microscopy (tem) and infrared spectrum (ir). quartz cell also was used as a substrate for building multilayer films to evaluate the capability of forming planar film. the result showed that ... | 2011 | 21465817 |
synthesis of chitosan/γ-fe2o3/fly-ash-cenospheres composites for the fast removal of bisphenol a and 2,4,6-trichlorophenol from aqueous solutions. | the chitosan/fly-ash-cenospheres/γ-fe(2)o(3) (cts/γ-fe(2)o(3)/facs) magnetic composites were prepared by microemulsion process. the resulting composites were characterized by xrd, ft-ir, sem, tga, dtg and vsm, and the results indicated that cts/γ-fe(2)o(3)/facs exhibited magnetic property (m(s)=6.553 emu g(-1)) and thermal stability, and composed of chitosan wrapping magnetic γ-fe(2)o(3) and fly-ash-cenospheres (thickness of the cross-linked chitosan was about 5.2 μm). then the cts/γ-fe(2)o(3)/f ... | 2011 | 21466912 |
one-dimensional multiferroic bismuth ferrite fibers obtained by electrospinning techniques. | we report the fabrication of novel multiferroic nanostructured bismuth ferrite (bifeo(3)) fibers using the sol-gel based electrospinning technique. phase pure bifeo(3) fibers were prepared by thermally annealing the electrospun bifeo(3)/polyvinylpyrrolidone composite fibers in air for 1 h at 600 °c. the x-ray diffraction pattern of the fibers (bifeo(3)) obtained showed that their crystalline structures were rhombohedral perovskite structures. both scanning electron microscopy (sem) and transmiss ... | 2011 | 21483046 |
cytoplasmic cul9/parc ubiquitin ligase is a tumor suppressor and promotes p53-dependent apoptosis. | a wide range of cell stresses, including dna damage, signal to p53 through posttranslational modification of p53. the cytoplasmic functions of p53 are emerging as an important constituent of role of p53 in tumor suppression. here, we report that deletion of the cul9 (formerly parc) gene, which encodes an e3 ubiquitin ligase that binds to p53 and localizes in the cytoplasm, resulted in spontaneous tumor development, accelerated eμ-myc-induced lymphomagenesis, and rendered mice susceptible to carc ... | 2011 | 21487039 |
ancient dna suggests dwarf and 'giant' emu are conspecific. | the king island emu (dromaius ater) of australia is one of several extinct emu taxa whose taxonomic relationship to the modern emu (d. novaehollandiae) is unclear. king island emu were mainly distinguished by their much smaller size and a reported darker colour compared to modern emu. | 2011 | 21494561 |
size and surface effects on the magnetic properties of nio nanoparticles. | nio nanoparticles (nps) were prepared by a sol-gel process using the citrate route. the sol-gel parameters were tuned to obtain samples with different average particle sizes, ranging from 12 to 70 nm. magnetic characterization revealed an increase in the blocking temperature with the diameter of the nps and an increase in the effective magnetic anisotropy (k(eff)) with decreasing particle size. the magnetic moment per particle was calculated for all samples using the susceptibility value at t = ... | 2011 | 21499610 |
facile synthesis of ultrasmall pegylated iron oxide nanoparticles for dual-contrast t1- and t2-weighted magnetic resonance imaging. | the development of new types of high-performance nanoparticulate mr contrast agents with either positive (t(1)) or dual-contrast (both positive and negative, t(1) + t(2)) ability is of great importance. here we report a facile synthesis of ultrasmall pegylated iron oxide nanoparticles for dual-contrast t(1)- and t(2)-weighted mri. the produced superparamagnetic iron oxide nanoparticles (spions) are of high crystallinity and size uniformity with an average diameter of 5.4 nm, and can be individua ... | 2011 | 21508500 |
enhancing transversal relaxation for magnetite nanoparticles in mr imaging using gd(3+)-chelated mesoporous silica shells. | a new magnetic nanoparticle was synthesized in the form of gd(3+)-chelated fe(3)o(4)@sio(2). the fe(3)o(4) nanoparticle was octahedron-structured, was highly magnetic (∼94 emu/g), and was the core of an encapsulating mesoporous silica shell. dota-nhs molecules were anchored to the interior channels of the porous silica to chelate gd(3+) ions. because there were gd(3+) ions within the silica shell, the transverse relaxivity increased 7-fold from 97 s(-1) mm(-1) of fe(3)o(4) to 681 s(-1) mm(-1) of ... | 2011 | 21513334 |
prenatal cardiovascular shunts in amniotic vertebrates. | during amniotic vertebrate development, the embryo and fetus employ a number of cardiovascular shunts. these shunts provide a right-to-left shunt of blood and are essential components of embryonic life ensuring proper blood circulation to developing organs and fetal gas exchanger, as well as bypassing the pulmonary circuit and the unventilated, fluid filled lungs. in this review we examine and compare the embryonic shunts available for fetal mammals and embryonic reptiles, including lizards, cro ... | 2011 | 21513818 |
misdiagnosis of epileptic seizures as manifestations of psychiatric illnesses. | epileptic seizures may be misdiagnosed if they manifest as psychiatric symptoms or seizures occur in patients with known psychiatric illness. | 2011 | 21515510 |
calibration of ac and dc magnetometers with a dy2o3 standard. | the ac susceptibility and magnetization curves of a glued dy(2)o(3) powder sample are measured by an ac susceptometer and a dc superconducting quantum interference device magnetometer, both of which have been calibrated previously. it is shown that the magnetic moment of the paramagnetic sample as a function of field and temperature may be accurately expressed by a combination of the curie-weiss law and the langevin function at t > 45 k with three adjusting parameters, so that the dc magnetizati ... | 2011 | 21529044 |
embryonic control of heart rate: examining developmental patterns and temperature and oxygenation influences using embryonic avian models. | long-term measurements (days and weeks) of heart rate (hr) have elucidated infradian rhythms in chicken embryos and circadian rhythms in chicken hatchlings. however, such rhythms are lacking in emu embryos and only rarely observed in emu hatchlings. parasympathetic control of hr (instantaneous heart rate (ihr) decelerations) occurs at ∼60% of incubation in both precocial and altricial avian embryos, with sympathetic control (ihr accelerations) becoming more prevalent close to hatching. a large i ... | 2011 | 21530689 |
electrospun polyvinylpyrrolidone fibers with high concentrations of ferromagnetic and superparamagnetic nanoparticles. | electrospun polymer fibers were prepared containing mixtures of different proportions of ferromagnetic and superparamagnetic nanoparticles. the magnetic properties of these fibers were then explored using a superconducting quantum interference device. mixed superparamagnetic/ferromagnetic fibers were examined for mesoscale magnetic exchange coupling, which was not observed as theoretically predicted. this study includes some of the highest magnetic nanoparticle loadings (up to 50 wt%) and the hi ... | 2011 | 21561090 |
unique magnetic properties of single crystal γ-fe2o3 nanowires synthesized by flame vapor deposition. | single crystal γ-fe(2)o(3) nanowires with 40-60 nm diameters were grown for the first time by single-step atmospheric flame vapor deposition (fvd) with axial growth rates up to 5 μm/minute. because of their superior crystallinity, these fvd γ-fe(2)o(3) nanowires are single magnetic domains with room temperature coercivities of 200 oe and saturation magnetizations of 68 emu/g. | 2011 | 21563788 |
characterization of new microsatellite markers derived from sequence databases for the emu (dromaius novaehollandiae). | the emu (dromaius novaehollandiae), a member of ratite family, is native to australia and has been introduced to other countries worldwide. in this work, 10 polymorphic microsatellite loci were isolated and characterized for emu from public sequences. polymorphism was surveyed in 22 individuals from two different populations kept in captivity. between two and 11 alleles were found per locus, and the observed heterozygosity ranged from 0.05 to 0.85, in accordance with expectations. these markers ... | 2008 | 21586070 |
cooperative function of ccr7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs. | lymphoma cell survival and progression is putatively dependent on a specific microanatomical localisation within secondary lymphoid organs. despite compelling data correlating homeostatic chemokine receptor expression and human lymphoma pathogenesis, genetic models that either mimic lymphoma dissemination or dissect a crosstalk of lymphoma and stromal cells are missing. applying the genetically tractable eμ-myc transgenic mouse model, we show that the chemokine receptor ccr7 regulates eμ-myc lym ... | 2011 | 21586747 |
non-cell-autonomous tumor suppression: oncogene-provoked apoptosis promotes tumor cell senescence via stromal crosstalk. | activated oncogenes evoke cellular fail-safe programs such as apoptosis, senescence, or autophagy to protect the organism from the expansion of damaged and potentially harmful cells. non-cell-autonomous interactions between tumor cells and nonmalignant bystander cells add to cell-autonomous modes of tumor suppression during tumor development and progression. in particular, the role of stroma or host immune cells converting tumor-generated signals into a response that feeds back to the tumor cell ... | 2011 | 21594578 |
probing the chemical stability of mixed ferrites: implications for mr contrast agent design. | nanomaterials with mixed composition, in particular magnetic spinel ferrites, are emerging as efficient contrast agents for magnetic resonance imaging (mri). many factors, including size, composition, atomic structure, and surface properties are crucial in the design of such nanoparticle-based probes due to their influence on the magnetic properties. silica-coated iron oxide (io-sio(2)) and cobalt ferrite (coio-sio(2)) nanoparticles were synthesized using standard high temperature thermal decomp ... | 2011 | 21603070 |
ccctc-binding factor (ctcf) and cohesin influence the genomic architecture of the igh locus and antisense transcription in pro-b cells. | compaction and looping of the ∼2.5-mb igh locus during v(d)j rearrangement is essential to allow all v(h) genes to be brought in proximity with d(h)-j(h) segments to create a diverse antibody repertoire, but the proteins directly responsible for this are unknown. because ccctc-binding factor (ctcf) has been demonstrated to be involved in long-range chromosomal interactions, we hypothesized that ctcf may promote the contraction of the igh locus. chip sequencing was performed on pro-b cells, revea ... | 2011 | 21606361 |
development of cll in the tcl1 transgenic mouse model is associated with severe skewing of the t-cell compartment homologous to human cll. | chronic lymphocytic leukemia (cll) cells require complex microenvironmental and immunologic interactions to survive and proliferate. such interactions might be best recreated in animal models; however, this needs extensive verification. we therefore investigated the composition of the t-cell compartment in the eμ-tcl1 transgenic mouse, currently the most widely used murine model for cll. immunophenotyping and transplant approaches were used to define t-cell subsets at various stages of cll. anal ... | 2011 | 21606964 |
effective heavy metal removal from aqueous systems by thiol functionalized magnetic mesoporous silica. | a thiol-functionalized magnetic mesoporous silica material (called sh-msi@fe(3)o(4)), synthesized by a modified stöber method, has been investigated as a convenient and effective adsorbent for heavy metal ions. structural characterization by powder x-ray diffraction, n(2) adsorption-desorption isotherm, fourier transform infrared spectroscopy and elemental analyses confirms the mesoporous structure and the organic moiety content of this adsorbent. the high saturation magnetization (38.4 emu/g) m ... | 2011 | 21616588 |
osteoinductivity of partially purified bovine, ostrich and emu bone morphogenetic proteins in vitro. | the aim of this study was to observe the osteogenic activity of native bone morphogenetic proteins (bmps) obtained from different species including bovine, ostrich and emu sources in order to compare mammalian and avian bmps. rat mesenchymal progenitor marrow stromal cells and pre-osteoblastic c2c12 cell cultures, were exposed to the native bmps and alkaline phosphatase (alp) and creatine kinase (ck) levels were determined by assay. the results showed that the alp activity in c2c12 cultures was ... | 2011 | 21630431 |
lack of tir8/sigirr triggers progression of chronic lymphocytic leukemia in mouse models. | inflammation is involved in the initiation and progression of several chronic lymphoid malignancies of b-cell type. toll-like receptors (tlr) are transmembrane inflammatory receptors that on recognition of pathogen-associated molecular patterns trigger an innate immune response and bridge the innate and adaptive immune response by acting as costimulatory signals for b cells. fine tuning of tlr and il-1r-like (ilr) activity is regulated by tir8 (sigirr), a transmembrane receptor of the tlr/ilr fa ... | 2011 | 21652674 |
preparation of rattle-type magnetic mesoporous carbon spheres and their highly efficient adsorption and separation. | novel rattle-type magnetic mesoporous carbon spheres are successfully prepared using composite spheres with fe(3)o(4) as core and mesoporous sio(2) as shell plus solid sio(2) as a middle layer as templates. these rattle-type spheres possess the magnetization strength of as high as 37.5 emu/g, high and tunable specific surface areas (382-512.6 m(2)/g) due to mesoporous carbon shells. this magnetic rattle-type structure and the readily accessible mesoporous shell are very favoring for the fast ads ... | 2011 | 21669442 |
characterization, chromosomal location, and genomic neighborhood of a ratite ortholog of a gene with gonadal expression in mammals. | a locus that we name suba was discovered during large-scale sequencing and characterization of a bacterial artificial chromosome library from an emu, dromaius novaehollandiae. this locus yields a significantly negative tajima's d in emus and is conserved across emu, chicken, mouse, and human. expression of suba orthologs has been reported in human ovaries and in mouse testes, but remains unknown in emus. the locus was physically mapped onto a pair of microchromosomes in emus by fluorescent in si ... | 2008 | 21669811 |
emu model of full-range femoral head osteonecrosis induced focally by an alternating freezing and heating insult. | the emu, a large bipedal bird with hip joint biomechanics similar to humans, was used to establish an experimental model of femoral head osteonecrosis and subsequent femoral head collapse. focal lesions were induced in 20 adult male emus using an alternating liquid nitrogen freezing and radiofrequency heating insult. at 2, 4, 8, 12 and 16 weeks post-surgery, hip magnetic resonance imaging (mri) was performed. before the emus were sacrificed, barium sulphate was infused to the lower extremity to ... | 2011 | 21672321 |
high magnetization and the high-temperature superparamagnetic transition with intercluster interaction in disordered zinc ferrite thin film. | magnetic properties have been investigated for a zinc ferrite thin film deposited on glass at a substrate temperature close to room temperature using a sputtering method. x-ray diffraction analysis reveals that the thin film consists of nanocrystalline znfe(2)o(4) with the size of approximately 10 nm. the magnetization at 300 k as a function of the external magnetic field shows ferrimagnetic behaviour, and tends to be saturated to the high value of 32 emu g(-1) when the external magnetic field i ... | 2005 | 21690674 |
magnetic properties of epitaxial heusler alloy (co(2/3)fe(1/3))(3+x)si(1-x)/gaas(001) hybrid structures. | the magnetic properties of full heusler alloy (co(2/3)fe(1/3))(3+x)si(1-x)/gaas(001) hybrid structures grown by molecular beam epitaxy have been investigated. the magnetic moment, the coercive field and the in-plane magnetic anisotropy of (co(2/3)fe(1/3))(3+x)si(1-x) films with various si compositions (-0.46≤x≤1) are discussed. the increase in amount of si results in a significant reduction in the cubic magnetocrystalline anisotropy constant |k(1)(eff)|. k(1)(eff) changes sign and saturates near ... | 2006 | 21690823 |
room-temperature ferromagnetism in pure and co doped ceo(2) powders. | we report the room-temperature (rt) ferromagnetism (fm) observed in pure and co doped ceo(2) powder. an insulating nonmagnetic ceo(2) single crystal, after grinding into fine powder, shows an rt-fm with a small magnetization of 0.0045 emu g(-1). however, the ceo(2) powder became paramagnetic after oxygen annealing, which strongly suggests an oxygen vacancy meditated fm ordering. furthermore, by doping co into ceo(2) powder the fm can significantly enhance through a f-centre exchange (fce) coupli ... | 2007 | 21694049 |
effect of co doping on the structural, optical and magnetic properties of zno nanoparticles. | we report the results of a detailed investigation of sol-gel-synthesized nanoscale zn(1-x)co(x)o powders processed at 350 °c with 0≤x≤0.12 to understand how the structural, morphological, optical and magnetic properties of zno are modified by co doping, in addition to searching for the theoretically predicted ferromagnetism. with x increasing to 0.03, both lattice parameters a and c of the hexagonal zno decreased, suggesting substitutional doping of co at the tetrahedral zn(2+) sites. for x>0.03 ... | 2007 | 21694080 |
quaternary record of aridity and mean annual precipitation based on +¦(15)n in ratite and dromornithid eggshells from lake eyre, australia. | the cause(s) of the late pleistocene megafauna extinction on the australian continent remains largely unresolved. unraveling climatic forcing mechanisms from direct or indirect human agents of ecosystem alteration has proven to be extremely difficult in australia due to the lack of (1) well-dated vertebrate fossils and (2) paleo-environmental and -ecological records spanning the past approximately 100-áka when regional climatic conditions are known to have significantly varied. we have examined ... | 2011 | 21706333 |
preparation and characterization of spindle-like fe3o4 mesoporous nanoparticles. | magnetic spindle-like fe3o4 mesoporous nanoparticles with a length of 200 nm and diameter of 60 nm were successfully synthesized by reducing the spindle-like α-fe2o3 nps which were prepared by forced hydrolysis method. the obtained samples were characterized by transmission electron microscopy, powder x-ray diffraction, attenuated total reflection fourier transform infrared spectroscopy, field emission scanning electron microscopy, vibrating sample magnetometer, and nitrogen adsorption-desorptio ... | 2011 | 21711591 |
the use of microsatellite polymorphism in genetic mapping of the ostrich (struthio camelus). | the aim of this study was to determine microsatellite polymorphism in ostriches and using it in creation the genetic map of the ostrich. the polymorphism analysis covered 30 microsatellite markers characteristic of ostrich, for the cau (china agricultural university) group. the material consisted of 150 ostriches (struthio camelus). the 30 microsatellite loci was examined and a total of 343 alleles was identified. the number of alleles at a single locus ranged from 5 at locus cau78 to 34 at locu ... | 2011 | 21717061 |
modern optics in exceptionally preserved eyes of early cambrian arthropods from australia. | despite the status of the eye as an "organ of extreme perfection", theory suggests that complex eyes can evolve very rapidly. the fossil record has, until now, been inadequate in providing insight into the early evolution of eyes during the initial radiation of many animal groups known as the cambrian explosion. this is surprising because cambrian burgess-shale-type deposits are replete with exquisitely preserved animals, especially arthropods, that possess eyes. however, with the exception of b ... | 2011 | 21720369 |
first-order reversal curves acquired by a high precision ac induction magnetometer. | we present a setup allowing to characterize the local irreversible behavior of soft magnetic samples. it is achieved by modifying a conventional ac induction magnetometer in order to measure first-order reversal curves (forcs), a magnetostatic characterization technique. the required modifications were performed on a home-made setup allowing high precision measurement, with sensibility less than 0.005 oe for the applied field and 10(-6) emu for the magnetization. the main crucial point for the f ... | 2011 | 21721706 |
sustained release of doxorubicin from zeolite-magnetite nanocomposites prepared by mechanical activation. | nanocomposites consisting of magnetite and fau zeolite with a high surface area and adsorption capacity have been prepared by mechanical activation using high-energy milling at room temperature. ftir results, as well as hrtem, eftem, and xps measurements, show that the resulting magnetic nanoparticles are covered by a thin aluminosilicate coating. a saturation magnetization as high as 16 emu g(-1) and 94.2 oe of coercivity were observed for the obtained composites. the main advantages of this sy ... | 2006 | 21727538 |
spark plasma sintered sm(2)co(17)-feco nanocomposite permanent magnets synthesized by high energy ball milling. | nanocomposite sm(2)co(17)-5 wt% feco magnets were synthesized by high energy ball milling followed by consolidation into bulk shape by the spark plasma sintering technique. the evolution of magnetic properties was systematically investigated in milled powders as well as in spark plasma sintered samples. a high energy product of 10.2 mgoe and the other magnetic properties of m(s) = 107 emu g(-1), m(r) = 59 emu g(-1), m(r)/m(s) = 0.55 and h(c) = 6.4 koe were achieved in a 5 h milled and spark plas ... | 2008 | 21730627 |
synthesis and characterization of monodisperse ultra-thin silica-coated magnetic nanoparticles. | a systematic study of the formation of silica-coated magnetite particles via a modified reverse microemulsion approach was investigated by using transmission electron microscopy (tem), x-ray diffraction (xrd) and a superconducting quantum interference device (squid). the results show that the surfactant igepal co-520 played an important role in the reaction system, and the thickness of the silica shell could be controlled by the concentration of the reaction agents. the developed ultra-thin sili ... | 2008 | 21730725 |
randomized comparison of the personality assessment inventory and the minnesota multiphasic personality inventory-2 in the epilepsy monitoring unit. | the two most common personality measures used in evaluation of patients on epilepsy monitoring units (emus) are the personality assessment inventory (pai) and the minnesota multiphasic personality inventory-2 (mmpi-2). both have been evaluated separately for their ability to distinguish patients with epilepsy from patients with psychogenic events, but they have never been compared directly. the primary aim of this study was to provide comparison data in an emu population between the pai, mmpi-2, ... | 2011 | 21733758 |
e++/mir-125b transgenic mice develop lethal b-cell malignancies. | microrna-125b-1 (mir-125b-1) is a target of a chromosomal translocation t(11;14)(q24;q32) recurrently found in human b-cell precursor acute lymphoblastic leukemia (bcp-all). this translocation results in overexpression of mir-125b controlled by immunoglobulin heavy chain gene (igh) regulatory elements. in addition, we found that six out of twenty-one bcp-all patients without t(11;14)(q24;q32) showed overexpression of mir-125b. interestingly, four out of nine patients with bcr/abl-positive bcp-al ... | 2011 | 21738213 |
modifying the surface of fe3o4/sio2 magnetic nanoparticles with c18/nh2 mixed group to get an efficient sorbent for anionic organic pollutants. | in this article, c(18)/nh(2) mixed group modified fe(3)o(4)/sio(2) magnetic nanoparticles (fe(3)o(4)/sio(2)/c(18)+nh(2) mnps) were successfully synthesized and used for the extraction of perfluorinated compounds (pfcs) from large volume of water solution. the fe(3)o(4)/sio(2)/c(18)+nh(2) mnps, about 25 nm in diameter, possess high extraction ability to the anionic organic pollutants due to the dual function of hydrophobic octadecyl group and cationic aminopropyl groups at low ph. more than 90% o ... | 2011 | 21741657 |
core-shell nayf(4):yb(3+),tm(3+)@fe(x)o(y) nanocrystals for dual-modality t(2)-enhanced magnetic resonance and nir-to-nir upconversion luminescent imaging of small-animal lymphatic node. | new core-shell structured nayf(4):yb(3+),tm(3+)@fe(x)o(y) nanocrystals, with 20-ánm-áyb(3+),tm(3+)-co-doped nayf(4) nanocrystals as a core and 5-ánm fe(x)o(y) nanocrystals as a shell, have been synthesized and characterized by tem and xrd analysis. these core-shell nanocrystals exhibit excellent near-infrared upconversion luminescence (ucl) emission at 800-ánm under excitation by a continuous-wave 980-ánm laser and superparamagnetic properties with a saturation magnetization (ms) of ôê+12-áemu/g ... | 2011 | 21742376 |
head-base bending and disjointed spermatozoa in the emu (dromaius novaehollandiae): a morphological comparison of two closely related defects. | the accurate assessment of avian sperm abnormalities is hampered by a lack of descriptive data and by the confusing terminology currently in use. critical appraisal of semen samples from the distal ductus deferens of the emu revealed that two closely related yet separate (distinct) defects previously collectively referred to as "bent sperm" or "crooked-necked sperm" could be identified by light and electron microscopy. head-base bending typically involved a 180° bend at the base of the nucleus w ... | 2011 | 21752445 |
thickness dependent magnetic and structural properties of co(x)cr(1-x) thin films evaporated on si(100) and glass substrates. | series of co(x)cr(1-x) thin films have been prepared by thermal evaporation onto si(100) and corning glass substrates, x ranging from 1 to 0.60, and the magnetic layer thickness from 17 to 220 nm. the dependence of the magnetic and crystallographic properties on the thickness of cocr layers have been investigated. the chromium content effect on the saturation magnetization of the films has also been examined. microscopic characterizations of the films, performed with x-ray diffraction (xrd) meas ... | 2011 | 21770102 |
dye adsorption characteristics of magnetite nanoparticles coated with a biopolymer poly(γ-glutamic acid). | magnetite nanoparticles coated with an anionic biopolymer poly(γ-glutamic acid) (pga-mnps) were synthesized and characterized for their methylene blue dye adsorption capability. both bare- and dye-loaded pga-mnps were characterized by ftir, tem and vsm measurements, revealing the pga-mnps to be superparamagnetic with average particle diameter being 12.4 nm and magnetization value 59.2 emu/g. the synthesized pga-mnps were stable in deionized, tap and river waters as well as in acidic and basic me ... | 2011 | 21775135 |
hierarchical assembly of sm2co7/co magnetic nanoparticles into highly stable and uniform nanospheres. | hierarchical assembly of colloidal sm2co7/co clusters in the form of nanospheres has been processed through a polyol process. the smco nanospheres are found to be robust, uniform ( 100 nm) and tend to self-assemble in the form of ordered superstructures. each nanosphere consists of large number of discrete fine particles ( 6.0 nm), having two-phase structure of both sm2co7 and co-phases. upon annealing, these phases transform into sm2co17 phase with very high magnetization (169 emu/g). a possibl ... | 2011 | 21776759 |
magnetic binary oxide particles (mbop): a promising adsorbent for removal of as (iii) in water. | magnetic binary oxide particles (mbop) synthesized using chitosan template has been investigated for uptake capacity of arsenic (iii). batch experiments were performed to determine the rate of adsorption and equilibrium isotherm and also effect of various rate limiting factors including adsorbent dose, ph, optimum contact time, initial adsorbate concentration and influence of presence cations and anions. it was observed that uptake of arsenic (iii) was independent of ph of the solution. maximum ... | 2011 | 21777934 |
synthesis and characterization of magnetic diphase znfe(2)o(4) /γ-fe(2)o(3) electrospun fibers. | magnetic nanofibers of znfe(2)o(4) / γ-fe(2)o(3) composite were synthesized by electrospinning from a sol-gel solution containing a molar ratio fe/zn of 3. the effects of the calcination temperature on the phase composition, particle size and magnetic properties have been investigated. zinc ferrite fibers were obtained by calcinating the electrospun fibers in air from 300 °c to 800 °c and characterized by thermogravimetric analyses, fourier transformed infrared spectroscopy, x-ray photoemission ... | 2011 | 21779141 |
multifunctional alginate microspheres for biosensing, drug delivery and magnetic resonance imaging. | this research aims to develop and investigate a multifunctional implantable system capable of biosensing, drug delivery and magnetic resonance imaging (mri) for continuous monitoring, controlled anti-inflammatory drug delivery and imaging, respectively. a glucose biosensor, diclofenac sodium (diclo) and magnetic nanoparticles (mnp) were used as the biosensor component, anti-inflammatory agent and mri contrast agent, respectively. mnp were synthesized by the co-precipitation technique and loaded ... | 2011 | 21784175 |
water-soluble superparamagnetic magnetite nanoparticles with biocompatible coating for enhanced magnetic resonance imaging. | ultrasmall superparamagnetic fe(3)o(4) nanoparticles (usirons) were synthesized by a novel, easily scalable chemical reduction of colloidal iron hydroxide under hydrothermal conditions. the average crystallite size (5.1 ± 0.5 nm) and good crystallinity of the samples were supported by hr-tem analysis and the saturation magnetization value (47 emu g(-1)). vitamin c, used as a chemical reducing agent, also served as a capping agent in the oxidized form (dehydroascorbic acid, dhaa) to impart nanopa ... | 2011 | 21790153 |
preparation of magnetic core mesoporous shell microspheres with c18-modified interior pore-walls for fast extraction and analysis of phthalates in water samples. | in this study, core-shell magnetic mesoporous microspheres with c18-functionalized interior pore-walls were synthesized through coating fe(3)o(4) microspheres with a mesoporous inorganic-organic hybrid layer with a n-octadecyltriethoxysilane (c18tes) and tetraethyl orthosilicate (teos) as the silica source and cetyltrimethylammonia bromide (ctab) as a template. the obtained c18-functionalized fe(3)o(4)@msio(2) microspheres possess numerous c18 groups anchored in the interior pore-walls, large su ... | 2011 | 21794868 |
synthesis and characterization of bracelet-like magnetic nanorings consisting of ag-fe3o4 bi-component nanoparticles. | stable bracelet-like magnetic nanorings, formed by ag-fe(3)o(4) nanoparticles with an average size around 40 nm, have been successfully prepared in large scale by means of reducing ag(+) and fe(3+) simultaneously under mild conditions. in the reaction, tiny grains of silver are used as seeds to prompt small fe(3)o(4) nanoparticles to grow larger, which is essential to enhance the magnetic dipole-dipole interactions, while only superparamagnetic fe(3)o(4) nanoparticles (about 10 nm in size) can b ... | 2011 | 21799984 |
polycyclic aromatic hydrocarbons profiles of spent drilling fluids deposited at emu-uno, delta state, nigeria. | the concentrations and profiles of polycyclic aromatic hydrocarbons were determined in spent drilling fluid deposited at emu-uno, delta state of nigeria. the total concentrations of polycyclic aromatic hydrocarbons in the spent drilling fluid deposits ranged between 40 and 770 μg kg(-1). the pahs profile were predominantly 2- and 3-rings with acenaphthalene, phenanthrene, fluorene being the predominant pahs. the prevalence of 2- and 3-rings pahs in the spent drilling fluid deposits indicate cont ... | 2011 | 21809098 |
observation of the room temperature magnetoelectric effect in dy doped bifeo(3). | polycrystalline bi(1-x)dy(x)feo(3) (x = 0.0, 0.03, 0.05, 0.07 and 0.1) ceramics have been prepared via a mixed oxide route. the effect of dy substitution on the dielectric, ferroelectric, and magnetic properties of the bifeo(3) multiferroic perovskite is studied. experimental results suggest that in the bi(1-x)dy(x)feo(3) system, increase of the dy concentration leads to effective suppression of the spiral spin structure of bifeo(3), resulting in the appearance of net magnetization. an anomaly i ... | 2009 | 21817206 |
structural, magnetic, and electrical studies on polycrystalline transition-metal-doped bifeo(3) thin films. | we have synthesized a range of transition-metal-doped bifeo(3) thin films on conducting silicon substrates using a spin-coating technique from metal-organic precursor solutions. bismuth, iron and transition-metal-organic solutions were mixed in the appropriate ratios to produce 3% transition-metal-doped samples. x-ray diffraction studies show that the samples annealed in a nitrogen atmosphere crystallize in a rhombohedrally distorted bifeo(3) structure with no evidence for any ferromagnetic seco ... | 2009 | 21817284 |
fabrication, characterization, and application of greigite nanoparticles for cancer hyperthermia. | greigite is a fe-s-containing complex having magnetic properties mainly synthesized in the solution. in the present study, greigite was synthesized by a coprecipitation method at different ph's and reaction times. the greigite phase was analyzed by the x-ray diffraction (xrd) method at an optimum ph of 3.0 and reaction time of 10min, respectively. the magnetization characterization by superconducting quantum interference device (squid) revealed that the magnetic saturation was obtained at 16.153 ... | 2010 | 21824623 |
magnetic properties of undoped cu(2)o fine powders with magnetic impurities and/or cation vacancies. | fine powders of micron- and submicron-sized particles of undoped cu(2)o semiconductor, with three different sizes and morphologies, have been synthesized by different chemical processes. these samples include nanospheres 200 nm in diameter, octahedra of size 1 µm and polyhedra of size 800 nm. they exhibit a wide spectrum of magnetic properties. at low temperature, t = 5 k, the octahedron sample is diamagnetic with the magnetic susceptibility χ(oh) = -9.5 × 10(-6) emu g(-1) oe(-1). the nanosphere ... | 2009 | 21825343 |
the yb(2)al(1-x)mg(x)si(2) series from a spin fluctuation (x = 0) to a magnetically ordered ground state (x = 1). | the structural and magnetic properties of yb(2)al(1-x)mg(x)si(2) (x = 0, 0.5 and 1), crystallizing in the tetragonal mo(2)feb(2)-type structure, are reported in this work. yb(2)alsi(2) exhibits a pauli paramagnetic ground state arising due to spin/valence fluctuations induced by a significant yb 4f conduction band hybridization. high-field magnetization (up to 120 koe) indicates a nearly temperature-independent susceptibility of 8.6 × 10(-3) emu/yb mol below 10 k. on the other hand, yb ions in y ... | 2009 | 21825437 |
the grafting and release behavior of doxorubincin from fe(3)o(4)@sio(2) core-shell structure nanoparticles via an acid cleaving amide bond: the potential for magnetic targeting drug delivery. | fe(3)o(4)@sio(2) core-shell structure nanoparticles were first prepared and characterized by tem, ftir, xps and xrd. subsequently the widely used anticancer agent doxorubincin (dox) was successfully grafted to the surface of the core-shell nanoparticles via an amide bond with the aid of a spacer arm we synthesized. the spacer arm met two needs: one end can couple to the core-shell nanoparticles' surface while the other end was the active -cooh group, which can react with the -nh(2) group of dox ... | 2008 | 21825634 |
synthesis of novel magnetic iron metal-silica (fe-sba-15) and magnetite-silica (fe(3)o(4)-sba-15) nanocomposites with a high iron content using temperature-programed reduction. | magnetic iron metal-silica and magnetite-silica nanocomposites have been prepared via temperature-programed reduction (tpr) of an iron oxide-sba-15 (sba: santa barbara amorphous) composite. tpr of the starting sba-15 supported fe(2)o(3) generated fe(3)o(4) and feo as stepwise intermediates in the ultimate formation of fe-sba-15. the composite materials have been characterized by means of x-ray diffraction, high resolution transmission electron microscopy and squid (superconducting quantum interf ... | 2008 | 21828658 |
flash fixation of heavy metals from two industrial wastes into ferrite by microwave hydrothermal co-treatment. | flash fixation of heavy metals from electroplating wastewater (epw) and pickling waste liquor (pwl) into ferrite lattice can be investigated by microwave hydrothermal process. the toxicity of wastewater may be reduced by the redox reaction between cr(vi) in electroplating wastewater and fe(ii) in pickling waste liquor. box-behnken design (bbd) experiment gives optimal process condition of ferrite formation as follows: wastewater volume ratio (v(pwl):v(epw) = 0.20), ph value 11 and retention time ... | 2011 | 21840124 |
efficacy of chk inhibitors as single agents in myc-driven lymphoma cells. | chk1 and chk2 function as effectors of cell cycle checkpoint arrest following dna damage. small molecule inhibitors of chk proteins are under clinical evaluation in combination with chemotherapeutic agents known to induce dna damage. we examined whether chk inhibitors could be effective as single agents in malignant cells with inherent dna damage because of deregulated expression of the oncogene c-myc. eμ-myc lymphoma cells showed a dramatic increase in the extent of dna damage and dna damage re ... | 2012 | 21841818 |
fluxomers: a new approach for 13c metabolic flux analysis. | the ability to perform quantitative studies using isotope tracers and metabolic flux analysis (mfa) is critical for detecting pathway bottlenecks and elucidating network regulation in biological systems, especially those that have been engineered to alter their native metabolic capacities. mathematically, mfa models are traditionally formulated using separate state variables for reaction fluxes and isotopomer abundances. analysis of isotope labeling experiments using this set of variables result ... | 2011 | 21846358 |
isolation of avian influenza virus (h9n2) from emu in china. | this is the first reported isolation of avian influenza virus (aiv) from emu in china. an outbreak of aiv infection occurred at an emu farm that housed 40 four-month-old birds. various degrees of haemorrhage were discovered in the tissues of affected emus. cell degeneration and necrosis were observed microscopically. electron microscopy revealed round or oval virions with a diameter of 80 nm to 120 nm, surrounded by an envelope with spikes. the virus was classified as low pathogenic aiv (lpaiv), ... | 2006 | 21851680 |
magnetic bioactive glass ceramic in the system cao-p2o5-sio2-mgo-caf2-mno2-fe2o3 for hyperthermia treatment of bone tumor. | magnetic bioactive glass ceramic (mg) in the system cao-sio(2)-p(2)o(5)-mgo-caf(2)-mno(2)-fe(2)o(3) for hyperthermia treatment of bone tumor was synthesized. the phase composition was investigated by xrd. the magnetic property was measured by vsm. the in vitro bioactivity was investigated by simulated body fluid (sbf) soaking experiment. cell growth on the surface of the material was evaluated by co-culturing osteoblast-like ros17/2.8 cells with materials for 7 days. the results showed that mg c ... | 2011 | 21870083 |
ultrathin zns single crystal nanowires: controlled synthesis and room-temperature ferromagnetism properties. | highly uniform single crystal ultrathin zns nanowires (nws) with 2 nm diameter and up to 10 μm length were fabricated using a catalyst-free colloidal chemistry strategy. the nanowires crystallized in hexagonal phase structure with preferential growth along the direction of the (001) basal plane. the strong polarity of the (001) plane composed of zn cations or s anions drives the oriented attachment of zns nanocrystals (ncs) along this direction via electrostatic (or dipole) interaction. the ultr ... | 2011 | 21870837 |
superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy. | the aim of this study describes the creation of superhigh-magnetization nanocarriers (shmncs) comprised of a magnetic fe(3)o(4) (shmnps) core and a shell of aqueous stable self-doped poly[n-(1-one-butyric acid)]aniline (spanh), which have a high drug loading capacity (∼27.1 wt%) of doxorubicin (dox). the shmncs display superparamagnetic property with a magnetization of 89.7 emu/g greater than that of resovist (a commercial contrast agent used for magnetic resonance imaging; 73.7 emu/g). conjugat ... | 2011 | 21872924 |
the cooperating mutation or "second hit" determines the immunologic visibility toward myc-induced murine lymphomas. | in eμ-myc transgenic animals lymphoma formation requires additional genetic alterations, which frequently comprise loss of p53 or overexpression of bcl-2. we describe that the nature of the "second hit" affects the ability of the immune system to contain lymphoma development. tumors with disrupted p53 signaling killed the host more rapidly than bcl-2 overexpressing ones. relaxing immunologic control, using tyk2(-/-) mice or by ab-mediated depletion of cd8(+) t or natural killer (nk) cells accele ... | 2011 | 21878673 |
psychogenic nonepileptic seizures in us veterans. | psychogenic nonepileptic seizures (pnes) are frequently encountered in epilepsy monitoring units (emu) and can result in significant long-term disability. we reviewed our experience with veterans undergoing seizure evaluation in the emu to determine the time delay to diagnosis of pnes, the frequency of pnes, and cumulative antiepileptic drug (aed) treatment. we compared veterans with pnes to civilians with pnes studied in the same emu. | 2011 | 21893668 |
preparation of magnetic core-mesoporous shell microspheres with c8-modified interior pore-walls and their application in selective enrichment and analysis of mouse brain peptidome. | in this paper, magnetic mesoporous silica microspheres with c8-modified interior pore-walls were prepared through a facile one-pot sol-gel coating strategy, and were successfully applied for selective enrichment of endogenous peptides in mouse brain for peptidome analysis. through the one-pot sol-gel approach with surfactant (ctab) as a template, tetraethyl orthosilicate (teos) and n-ctyltriethoxysilane (c8teos) as the precursors, c8-modified magnetic mesoporous microspheres (c8-fe(3)o(4)@msio(2 ... | 2011 | 21905222 |
[a new animal model of osteonecrosis induced by focal alternative cooling and heating insults]. | to establish a new animal model of osteonecrosis of the femoral head(onfh) with improved consistency and incidence of femoral head collapse for studies on the mechanism of osteonecrosis. and on the assessment of treatment effectiveness. | 2011 | 21906444 |
rescue of hiv-1 broad neutralizing antibody-expressing b cells in 2f5 vh x vl knockin mice reveals multiple tolerance controls. | the hiv-1 broadly neutralizing ab (bnab) 2f5 has been shown to be poly-/self-reactive in vitro, and we previously demonstrated that targeted expression of its vdj rearrangement alone was sufficient to trigger a profound b cell developmental blockade in 2f5 v(h) knockin (ki) mice, consistent with central deletion of 2f5 h chain-expressing b cells. in this study, we generate a strain expressing the entire 2f5 bnab specificity, 2f5 v(h) × v(l) ki mice, and find an even higher degree of tolerance co ... | 2011 | 21908739 |
a smart multifunctional nanocomposite for intracellular targeted drug delivery and self-release. | a multifunctional 'all-in-one' nanocomposite is fabricated using a colloid, template and surface-modification method. this material encompasses magnetic induced target delivery, cell uptake promotion and controlled drug release in one system. the nanocomposite is characterized by scanning electron microscopy, transmission electron microscopy, x-ray diffraction, n(2) adsorption and vibrating sample magnetometry. the prepared material has a diameter of 350-400 nm, a high surface area of 420.29 m(2 ... | 2011 | 21914934 |
preparation of magnetically separable n-halamine nanocomposites for the improved antibacterial application. | magnetic n-halamine nanocomposites were synthesized through the encapsulation of the magnetic silica nanoparticles with antibacterial n-halamine polymer. the as-synthesized sample was characterized by transmission electron microscopy (tem), dynamic light scattering (dls), fourier transform infrared (ftir), x-ray diffraction (xrd), x-ray photoelectron spectra (xps), and thermogravimetric analysis (tga). the fabricated magnetic n-halamine nanocomposites possessed enhanced antibacterial activity ag ... | 2011 | 21925670 |
peg coating reduces nmr relaxivity of mn(0.5)zn(0.5)gd(0.02)fe(1.98)o4 hyperthermia nanoparticles. | to investigate both t1 and t2 mr relaxation enhancement of gd substituted zn-mn ferrite magnetic nanoparticles. both uncoated and polyethylene glycol (peg) coated particles were used. | 2011 | 21928382 |
characterization of a new arid family transcription factor (brightlike/arid3c) that co-activates bright/arid3a-mediated immunoglobulin gene transcription. | two members, bright/arid3a and bdp/arid3b, of the arid (at-rich interaction domain) transcription family are distinguished by their ability to specifically bind to dna and to self-associate via a second domain, rekles. bright and bdp positively regulate immunoglobulin heavy chain gene (igh) transcription by binding to at-rich motifs within matrix associating regions (mars) residing within a subset of v(h) promoters and the eμ intronic enhancer. in addition, rekles provides bright nuclear export ... | 2011 | 21955986 |
lymphomas that recur after myc suppression continue to exhibit oncogene addiction. | the suppression of oncogenic levels of myc is sufficient to induce sustained tumor regression associated with proliferative arrest, differentiation, cellular senescence, and/or apoptosis, a phenomenon known as oncogene addiction. however, after prolonged inactivation of myc in a conditional transgenic mouse model of eμ-tta/teto-myc t-cell acute lymphoblastic leukemia, some of the tumors recur, recapitulating what is frequently observed in human tumors in response to targeted therapies. here we r ... | 2011 | 21969595 |
carboxyl and negative charge-functionalized superparamagnetic nanochains with amorphous carbon shell and magnetic core: synthesis and their application in removal of heavy metal ions. | this communication describes carboxyl-functionalized nanochains with amorphous carbon shell (18 nm) and magnetic core using ferrocene as a single reactant under the induction of an external magnetic field (0.40 t), which shows a superparamagnetic behavior and magnetization saturation of 38.6 emu g(-1). because of mesoporous structure (3.8 nm) and surface negative charge (-35.18 mv), the nanochains can be used as adsorbent for removing the heavy metal ions (90%) from aqueous solution. | 2011 | 21975557 |
a species tree for the australo-papuan fairy-wrens and allies (aves: maluridae). | we explored the efficacy of species tree methods at the family level in birds, using the australo-papuan fairy-wrens (passeriformes: maluridae) as a model system. fairy-wrens of the genus malurus are known for high intensities of sexual selection, resulting in some cases in rapid speciation. this history suggests that incomplete lineage sorting (ils) of neutrally evolving loci could be substantial, a situation that could compromise traditional methods of combining loci in phylogenetic analysis. ... | 2012 | 21978990 |
two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus. | the immunoglobulin heavy-chain (igh) gene locus undergoes radial repositioning within the nucleus and locus contraction in preparation for gene recombination. we demonstrate that igh locus conformation involves two levels of chromosomal compaction. at the first level, the locus folds into several multilooped domains. one such domain at the 3' end of the locus requires an enhancer, eμ; two other domains at the 5' end are eμ independent. at the second level, these domains are brought into spatial ... | 2011 | 21982154 |
inducing growth of feni-pt match-like magnetic nanoheterostructures on pt nanotips and dechlorination of hydrochloric ether. | newly designed magnetic feni-pt match-like heterostructured nanorods were synthesized by means of induced growth of feni nanorods on pt nanotips. the proposed synthesis mechanism is corroborated by sem, tem, xrd and xps. the magnetic behavior shows that the magnetic saturation and coercivity are strongly dependent on both the shape and the alloy composition. the saturation magnetizations (ms) and the coercivity (hc) of nanorods synthesized are larger than those of nanoparticles because of the re ... | 2011 | 21990147 |
gold-silver alloy nanoshells: a new candidate for nanotherapeutics and diagnostics. | we have developed novel gold-silver alloy nanoshells as magnetic resonance imaging (mri) dual t1 (positive) and t2 (negative) contrast agents as an alternative to typical gadolinium (gd)-based contrast agents. specifically, we have doped iron oxide nanoparticles with gd ions and sequestered the ions within the core by coating the nanoparticles with an alloy of gold and silver. thus, these nanoparticles are very innovative and have the potential to overcome toxicities related to renal clearance o ... | 2011 | 21995302 |
design and characterization of ni2+ and co2+ decorated porous magnetic silica spheres synthesized by hydrothermal-assisted modified-stöber method for his-tagged proteins separation. | the complete elimination of enzymes from the reaction mixture and the possibility of its recycling for several rounds result in great benefits, allowing the reduction of the enzyme consumption and their usability in continuous processes. in this work, it is evaluated the capture of a h6-tagged green fluorescence protein (gfp-h6) on porous magnetic spheres using the co(2+) and ni(2+) affinity adsorption as a possible cost-effective and up-scaled alternative way for the immobilization of his-tagge ... | 2012 | 21996010 |
selective recognition of sesamol using molecularly imprinted polymers containing magnetic wollastonite. | the magnetic molecularly imprinted polymers (mmips) have been synthesized using piperonal molecules as dummy template and magnetic wollastonite composites as support. the resulting composites were applied to selective recognition of sesamol from aqueous solution. mmips were characterized by scanning electron microscopy (sem), fourier transform infrared (ft-ir) analysis, transmission electron microscopy (tem), energy dispersive spectroscopy (eds), thermogravimetric analysis (tga), and vibrating s ... | 2011 | 21997999 |
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. | We previously demonstrated that the gene encoding PTPROt, the truncated form of protein tyrosine phosphatase receptor type O expressed predominantly in hematopoietic cells, is a candidate tumor suppressor and is down-regulated in chronic lymphocytic leukemia (CLL). Here, we show that PTPROt expression is significantly reduced in CD19(+) spleen B cells from Eµ-T cell leukemia 1 (TCL1) transgenic mice relative to the wild-type mice. Strikingly, as much as a 60% decrease in PTPROt expression occurs ... | 2011 | 22001392 |
modifying fe3o4-functionalized nanoparticles with n-halamine and their magnetic/antibacterial properties. | magnetic/antibacterial bifunctional nanoparticles were fabricated through the immobilization of antibacterial n-halamine on silica-coated fe(3)o(4)-decorated poly(styrene-co-acrylate acid) (psa) nanoparticles. the samples were characterized by scanning electron microscopy (sem), transmission electron microscopy (tem), x-ray photoelectron spectra (xps), x-ray diffraction (xrd), energy-dispersive x-ray spectrometry (edx), fourier transform infrared (ftir), and thermogravimetric analysis (tga). the ... | 2011 | 22008460 |
Isolation and identification of highly pathogenic avian influenza virus subtype H5N1 from emus from the Ein Gedi oasis by the Dead Sea. | An avian influenza virus (AIV), A/Emu/Israel/552/2010/(H5N1), was isolated from a dead emu that was found in the Ein Gedi oasis near the Dead Sea. The virus molecular characterization was performed by reverse transcriptase-polymerase chain reaction (RT-PCR) and real-time RT-PCR using AIV subtype-specific primers. The virus was of high pathogenicity, according to its intravenous pathogenicity index of 2.85 and the nucleotide sequencing at the cleavage site of the hemagglutinin gene, GERRRKKR, whi ... | 2011 | 22017055 |
Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation. | The functions of key oncogenic transcription factors independent of context have not been fully delineated despite our richer understanding of the genetic alterations in human cancers. The MYC oncogene, which produces the Myc transcription factor, is frequently altered in human cancer and is a major regulatory hub for many cancers. In this regard, we sought to unravel the primordial signature of Myc function by using high-throughput genomic approaches to identify the cell-type independent core M ... | 2011 | 22039435 |
molecular characterization of goose- and chicken-type lysozymes in emu (dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. | lysozyme (lz), a bacteriolytic enzyme, is found in the egg white of many avian eggs and plays an important role in host defense; however, lz activity in emu (dromaius novaehollandiae) egg white is exceptionally undetectable. we cloned and characterized emu goose-type lz (lzg) and chicken-type lz (lzc) genes. rt-pcr analysis revealed very low lzg gene expression levels and absence of lzc gene expression in the emu oviduct. sequencing of full-length lzg and lzc cdnas indicated that their amino aci ... | 2012 | 22044478 |
magnetic manipulation and optical imaging of an active plasmonic single-particle fe-au nanorod. | superparamagnetic microbeads play an important role in a number of scientific and biotechnology applications including single-molecule force measurements, affinity separation, and in vivo and in vitro diagnostics. magneto-optically active nanorods composed of single-crystalline au and polycrystalline fe segments were synthesized with diameters of 60 or 295 nm using templated electrodeposition. the fe section was magnetically soft and had a saturation magnetization of approximately 200 emu/g, res ... | 2011 | 22046955 |
high sensitivity detection of radio-frequency modulated magnetic moment in semiconductors. | an experimental setup has been realized to measure weak magnetic moments which can be modulated at radio frequencies (~1-5 mhz). using an optimized radio-frequency (rf) pickup coil and lock-in amplifier, an experimental sensitivity of 10(-15) am(2) corresponding to 10(-18) emu has been demonstrated with a 1 s time constant. the detection limit at room temperature is 9.3 × 10(-16) am(2)/√hz limited by johnson noise of the coil. the setup has been used to directly measure the magnetic moment due t ... | 2011 | 22047310 |
inhomogeneous electronic states in organic metal (bedo-ttf)(2)reo(4)·h(2)o: epr and squid study. | it is shown by electron paramagnetic resonance (epr) and superconducting quantum interference device (squid) magnetometry that two spin systems coexist in conducting layers of the quasi-2d organic metal (bedo-ttf)(2)reo(4)·h(2)o: delocalized moments of charge carriers (holes), i(epr)(300 k) = 1.62 × 10(-4) emu mol(-1), and localized moments on bedo-ttf(+1), χ(p)(300 k) = 4.25 × 10(-4) emu mol(-1). the phase transition me-me' at t(c) = 203 k is detected in paramagnetic relaxation, epr amplitude a ... | 2007 | 22049109 |
meat quality traits in the emu (dromaius novaehollandiae) as affected by muscle type and animal age. | meat quality traits were determined in the major muscles of the emu (dromaius novaehollandiae) at different slaughter ages (6, 10, 14, 17 or =20 months). a mean ultimate ph value of 5.5 was reached within around 3 h post mortem, but this value was 6.1 in animals that had suffered a preslaughter stress (transportation and fasting). the collagen and pigment contents varied widely among the muscles. the protein and pigment contents increased with animal age, but this effect was perceptible only bet ... | 1997 | 22061304 |
differentiation of the species ostrich (struthio camelus) and emu (dromaius novaehollandiae) by polymerase chain reaction using an ostrich-specific primer pair. | through polymerase chain reaction a zone of the gene for the cytochrome b of ostrich (struthio camelus) mitochondrial dna was amplified using a primer pair which permits to identify the ostrich and differentiate it from the emu (dromaius novaehollandiae), thus giving different size fragment; in the ostrich of about 543 bp and in the emu of about 229 bp. this has been obtained without adopting other techniques such as, e.g., the fragment digestion by means of suitable restriction enzymes or singl ... | 2000 | 22061765 |
response of spermatozoa from the emu (dromaius novaehollandiae) to rapid cooling, hyperosmotic conditions and dimethylacetamide (dma). | three experiments conducted to improve the survival of emu sperm during cryopreservation aimed to: (1) minimize chilling injury during the cooling phase; (2) determine the osmotic effects of dimethylacetamide (dma), sucrose and trehalose; and (3) investigate the timing and nature of cryoprotectant toxicity. we measured sperm membrane integrity, motility, morphology and egg membrane penetration. in experiment 1, semen diluted 1:1 with a pre-cooled diluent (5°c) prevented chilling injury. in exper ... | 2011 | 22078301 |
Suppression of Myc oncogenic activity by nucleostemin haploinsufficiency. | Nucleostemin (NS), a nucleolar GTPase, is highly expressed in stem/progenitor cells and in most cancer cells. However, little is known about the regulation of its expression. Here, we identify the NS gene as a novel direct transcriptional target of the c-Myc oncoprotein. We show that Myc overexpression enhances NS transcription in cultured cells and in pre-neoplastic B cells from Eµ-myc transgenic mice. Consistent with NS being downstream of Myc, NS expression parallels that of Myc in a large pa ... | 2011 | 22081066 |
Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression. | Overexpression of the transcriptional regulator Myc is thought to be the cause or a contributing factor in the development of a large number of human lymphomas and certain other cancers. Apoptotic cell death constitutes a tumor suppressive mechanism, particularly in the context of Myc overexpression. Accordingly, lymphoma development in Eµ-Myc transgenic mice, which mimic the Myc/IgH chromosomal translocation that causes Burkitt lymphoma, is accelerated by concomitant overexpression of anti-apop ... | 2011 | 22081075 |
improving safety outcomes in the epilepsy monitoring unit. | long term video electroencephalography (eeg) in epilepsy monitoring units (emu) is used to diagnose and treat patients with epilepsy. injury occurs in the emu, including reports of death. no standardized patient safety protocols exist. our objective is to determine the frequency and contributing factors to injury in the emu. we reviewed medical records and video eeg of patients with epilepsy admitted to our emu from december 1, 2008 to june 1, 2009. data was collected on seizure type, onset, len ... | 2012 | 22093593 |
synthesis of air stable iron nanopowders with various methods. | magnetic properties and microstructures of iron-based nanopowders fabricated by several methods, such as sol-gel, thermal decomposition, and self-propagating combustion methods, were investigated. during a subsequent reduction annealing, added aluminum atoms formed coherent oxide shells with a hercynite structure around iron cores in all the nanopowders. in particular, the nanopowders synthesized by the self-propagating combustion method showed the highest saturation magnetization of 175.68 emu/ ... | 2011 | 22103172 |
search for new physics in high pt like-sign dilepton events at cdf ii. | we present a search for new physics in events with two high pt leptons of the same electric charge, using data with an integrated luminosity of 6.1 fb(-1). the observed data are consistent with standard model predictions. we set 95% c.l. lower limits on the mass of doubly charged scalars decaying to like-sign dileptons, m(h±±) > 190-245 gev/c(2), assuming 100% br to ee, μμ or eμ. | 2011 | 22107622 |