Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| specific diagnostic antigens of echinococcus granulosus detected by western blot. | a western blot assay was performed for the detection of echinococcus granulosus specific antigens useful for the diagnostic of hydatic disease. 191 sera were tested, 105 coming from patients with different localizations of hydatic cysts and 86 from persons either healthy or presenting other diseases. 48 different antigenic bands were detected using sera from patients with hydatidosis. a 35 kda antigen co-migrating with a band labeled by a mcab specific of antigen 5 was recognized in western blot ... | 1995 | 7582376 |
| echinococcus granulosus, e. multilocularis and mammalian liver-type alkaline phosphatases: a comparative study. | the alkaline phosphatases (ec 3.1.3.1) from echinococcus granulosus and e. multilocularis (cestoda) were compared to each other and to a liver-type enzyme. the purified proteins (210 and 220 kda, respectively) had a tetrameric structure composed of 4, 56/53 kda subunits. enzymatic removal of their n-linked sugar moieties abolished the differences in their apparent molecular weight under reducing conditions. after phase separation in triton x-114, the e. multilocularis enzyme was the most amphiph ... | 1995 | 7584859 |
| immunological markers indicating the effectiveness of pharmacological treatment in human hydatid disease. | the relation of interferon-gamma (ifn-gamma), il-4, il-10 production and specific ige, total igg, igg subclass expression to the effectiveness of pharmacological treatment in human hydatid disease (echinococcus granulosus infection) was evaluated in 27 hydatid patients divided into four clinical groups according to their response to albendazole/mebendazole therapy (full, partial, low and non-responders). after parasite antigen stimulation, peripheral blood mononuclear cells (pbmc) from full resp ... | 1995 | 7586679 |
| echinococcus granulosus infections of dogs in the durazno region of uruguay. | the prevalence and distribution of echinococcus granulosus in domestic dogs was examined in three dog populations in the durazno region of uruguay. the prevalence was 19.7 per cent in 704 dogs successfully purged with arecoline hydrobromide. higher prevalences were detected in dogs from the rural area (30.0 per cent) and the village of la paloma (25.9 per cent) than in the town of sarandi del yi (7.9 per cent). the frequency distribution of e granulosus was overdispersed (k, the negative binomia ... | 1995 | 7604519 |
| [isolated echinococcosis of the lung]. | this is a report of a 81 year old women with a cyst of echinococcus granulosus, that was almost completely taking over the lower lobe of the left lung. this case study shows on one hand the diagnosis of echinococcosis is a part of the differential diagnosis even for an elderly patient. on the other hand we were able to demonstrate, that elderly patients can benefit from the surgical treatment especially since medication has a lot of side effects and a fairly high rate of failures. | 1995 | 7607018 |
| isolation and characterization of species-specific dna probes from taenia solium and taenia saginata and their use in an egg detection assay. | cysticercosis results from ingestion of the eggs of the tapeworm taenia solium. reduction of the incidence of human and swine cysticercosis requires identification and treatment of individuals who carry the adult tapeworm. t. solium and taenia saginata eggs cannot be differentiated on the basis of morphology; thus, in order to improve existing methods for the diagnosis of taeniasis, we have developed highly sensitive, species-specific dna probes which differentiate t. solium and t. saginata. rec ... | 1995 | 7615742 |
| lack of an association between hydatid disease and autoimmunity. | the prolonged survival of echinococcus granulosus within the human host indicates that some mechanism is operating to permit parasite evasion of the host immune response. several publications have described autoimmune phenomena in patients infected with hydatid cysts. the aim of this study was to test the postulate that there is a higher prevalence of autoantibodies in serum from patients with hydatid disease than in control samples, and this may provide some evidence of an association between a ... | 1995 | 7624162 |
| echinococcus granulosus: observations on strobilar development in in vitro monophasic culture. | the in vitro cultivation technique of echinococcus granulosus protoscoleces usually states the necessity of a biphasic medium with a solid protein substrate for strobilar development to take place; otherwise, in a monophasic medium, protoscoleces follow a vesicular development. however, in some monophasic cultures, the development of several strobilate individuals (in different quantities and stages of development, depending on the culture) were observed. the only known difference from cultures ... | 1995 | 7636162 |
| identification and characterization of myophilin, a muscle-specific antigen of echinococcus granulosus. | a muscle-specific gene of echinococcus granulosus has been identified and characterized. a lambda gt11 clone (10p1), containing an incomplete copy of the gene, was originally isolated from a larval e. granulosus cdna library by serum antibodies from dogs infected with the parasite. the full-length cdna sequence was obtained by pcr amplification of cdna from an adult e. granulosus lambda gt22a library. southern blot analysis indicated the presence of the gene as a single copy in the genome of e. ... | 1995 | 7637694 |
| [pulmonary echinococcosis]. | two patients with pulmonal echinococcosis are presented by the authors. contact with cestoda carrier animals cannot be revealed. at the first patient, who was without any complaints, the two round shadows in her chest x-ray were detected accidentally by screening examination and before the operation only eosinophilia, many eosinophil granulocytes in the pleural effusion and the positive complement binding reaction were related to the echinococcosis, which was proved by the histological examinati ... | 1995 | 7651716 |
| [epidemiology of echinococcosis in bavaria]. | there are few and incomplete data about the epidemiology of echinococcosis in germany. the aim of this retrospective study was to collect informations about frequency and distribution of this parasitosis in one of the main endemic regions (bavaria). | 1995 | 7656847 |
| maternal transfer of protection from echinococcus granulosus infection in sheep. | although passive immunity against larval metacestodes of the genus taenia is well established, the transfer of immunity against echinococcus granulosus infection has not been demonstrated convincingly. the immune status of newborn lambs born to ewes that had been infected or immunised with e granulosus eggs or oncospheres was investigated. the ewes and their six- to eight-day-old lambs were subsequently challenged. lambs born to triply infected ewes were 80 per cent protected from a challenge in ... | 1995 | 7659840 |
| effects of mebendazole, albendazole, and praziquantel on glutathione s-transferase and superoxide dismutase of echinococcus granulosus cyst wall harbored in mice. | to explore the existence of glutathione s-transferase (gst) and superoxide dismutase (sod) in echinococcus granulosus cyst, and the effect of anthydatid drugs on these 2 enzymes, mice infected with e granulosus protoscoleces for 10-12 months were used. | 1995 | 7668094 |
| sonographic findings in hydatid disease of the liver: comparison with other imaging methods. | patients with hepatic hydatid disease were examined by sonography (n = 62), plain radiography (n = 62), computerized tomography (ct; n = 25) and/or isotope scans (n = 31). the clinical presentation ranged from asymptomatic to right upper quadrant complaints and, rarely, remote symptoms. plain radiology showed liver calcifications in 26% of the cases tested; half of the calcifications were in collapsed, flattened cysts. sonography, the investigation of choice, since it is cheap, non-invasive and ... | 1995 | 7668917 |
| study of the in vitro activation of the complement alternative pathway by echinococcus granulosus hydatid cyst fluid. | in the present study we have investigated the fluid phase activation of the complement (c) alternative pathway by echinococcus granulosus sheep hydatid cyst fluid (shcf) and its higher molecular weight fraction (shcf-i) by quantitating the formation of both the terminal c intermediary c5b6 complex and the terminal c complex (tcc). our results show that in vitro c activation progresses beyond the c5 step suggesting that potentially lytic complexes may be generated in vivo. in addition, shcf and s ... | 1995 | 7675511 |
| analysis of taeniid antigens using monoclonal antibodies to echinococcus granulosus antigen 5 and antigen b. | antigens derived from echinococcus granulosus, taenia hydatigena and t. pisiformis cyst fluids, t. solium cysticerci, e. multilocularis protoscoleces and e. vogeli cyst membranes were examined by enzyme-linked immunosorbent assay (elisa) and immunoelectrophoresis (iep) using four monoclonal antibodies (mab) to e. granulosus antigen 5 (ag5) and antigen b (agb). anti-ag5 mabs 24.14 and 61a12 reacted strongly with t. hydatigena and t. pisiformis cyst fluids and, to a lesser degree, anti-agb mabs 31 ... | 1993 | 7682330 |
| echinococcus granulosus:isoprinosine treatment of the metacestode stage. | the efficacy of short- and long-term treatments with isoprinosine, an immunomodulatory compound, was studied in echinococcus granulosus cysts developed in nmri mice intraperitoneally infected with sheep pulmonary cysts. after treatment, a reduction in the size and number of cysts with macroscopic modifications was observed. the structural alterations included damage or destruction of the protoscoleces and partial destruction of the cyst wall, which predominated at the inner germinal layer level. ... | 1993 | 7685983 |
| effect of mebendazole on free amino acid composition of cyst wall and cyst fluid of echinococcus granulosus harbored in mice. | eighteen and 23 faa components were detected in the cyst wall and cyst fluid of e granulosus, respectively, by using automatic amino acid analyzer. the concentrations of most of the determined faa were higher in the cyst fluid than those in the cyst wall, especially the taurine was 5-fold higher. mebendazole treatment resulted in an increase in the concentration of alanine, valine, lysine, and taurine in both cyst wall and cyst fluid, the most notable being the alanine in the cyst wall. the resu ... | 1994 | 7709751 |
| immunological assessment of exposure to echinococcus granulosus in a rural dog population in uruguay. | an elisa was used to screen a dog population in uruguay (sarandi del yi, durazno district) for the prevalence of specific serum antibodies (igg, iga and ige) to echinococcus granulosus. the sensitivity (61%) and specificity (97%) of the elisa were determined using well-defined serum groups. a total of 408 dogs from sarandi del yi and environs were screened serologically, and 29.7% (8.6-13.8% for each antibody class) of dogs had positive levels of antibody to e. granulosus. this antibody prevalen ... | 1994 | 7709857 |
| preparation and sequence analysis of taenia crassiceps metacestode recombinant antigens with potential for specific immunodiagnosis of human cerebral cysticercosis. | a taenia crassiceps metacestode cdna expression library in lambda gt 11 was screened with rabbit antisera to metacestodal t. solium and t. saginata crude extract. primary clones (121) were identified, and after rescreening and lysogenization in escherichia coli y 1089, were tested in western blot for reactivity with the same antisera. in addition, analyses were performed with rabbit antisera directed towards t. crassiceps and echinococcus granulosus metacestode crude extract, sera from humans wi ... | 1994 | 7716396 |
| echinococcus granulosus: interactions with host complement in secondary infection in mice. | complement has been shown to lyse protoscoleces of echinococcus granulosus, but products from this parasite are able to consume complement, and this has been proposed as an evasion mechanism. the murine secondary hydatidosis model, with intraperitoneal inoculation, is used in this work to assess the occurrence in vivo of complement consumption by the parasite as well as the role of complement during the establishment of infection. although the measurement of systemic levels of c3 activation, tot ... | 1995 | 7729482 |
| [13c]-nuclear magnetic resonance spectral profiles of serum from normal and echinococcus granulosus-infected mice: a kinetic study. | 1995 | 7731927 | |
| the diagnostic importance of species specific and cross-reactive components of taenia solium, echinococcus granulosus, and hymenolepis nana. | sera from patients infected with taenia solium, hymenolepis nana and echinococcus granulosus were tested against homologous and heterologous parasite antigens using an elisa assay, and a high degree of cross-reactivity was verified. to identify polypeptides responsible for this cross reactivity, the enzyme linked immunoelectro transfer blot (eitb) was used. sera from infected patients with t.solium, h.nana, and e.granulosus were assessed against crude, ammonium sulphate precipitated (tsasp), and ... | 1994 | 7732263 |
| evaluating the activity of liver cystic echinococcosis using the delayed-hypersensitivity skin reaction to common antigens. | when 11 patients with active liver cystic echinococcosis were tested with a commercial, delayed-hypersensitivity, skin test (dhst) to seven common antigens (multitest; merieux institute, lyon) they all reacted less than 30 patients with non-parasitic liver cysts, who had normal reactions. this immunosuppression in cystic echinococcosis was transient, as dhst performed within a few months of treatment were normal. dhst may help in evaluating the activity of echinococcus granulosus cysts. | 1995 | 7741591 |
| partial purification and comparison of the kinetic properties of ovine liver echinococcus granulosus hydatid cyst fluid malate dehydrogenase and the cytoplasmic enzyme from the host liver. | ovine liver echinococcus granulosus hydatid cyst fluid and cytoplasmic healthy ovine liver malate dehydrogenases were purified 24- and 30-fold by sephadex g-200 and deae-sephadex chromatography. both enzymes were eluted with the same elution volume and the same salt concentration from the respective columns. the ph optimum of the enzymes from both sources was 8.4 in either tris-hcl or barbital buffer. the km values for oxaloacetate were 0.211 and 0.200 mm for hydatid cyst fluid and healthy ovine ... | 1994 | 7749613 |
| idiotypic modulation of the antibody response of mice to echinococcus granulosus antigens. | in this work we analysed the modulation of the antibody response to echinococcus granulosus antigens via anti-idiotype (ab2) administration. in a first set of experiments, we determined the antibody response to hydatid cyst fluid antigen (hcfa) of mice immunized with ab2. results showed that ab2 elicited anti-hcfa antibodies in mice that had never been exposed to hcfa before. moreover, that response was characterized by booster effect, avidity maturation and an inverse correlation between avidit ... | 1995 | 7751015 |
| diagnosis of canine echinococcosis: comparison of coproantigen and serum antibody tests with arecoline purgation in uruguay. | echinococcus granulosus is one of the most important and widespread of the helminth zoonoses. diagnosis of e. granulosus infection in dogs currently relies on arecoline dosing and detailed examination of the purge for adult worms. two immunodiagnostic tests (elisa) based on genus specific coproantigen detection or serum antibody (igg, iga and ige) detection were compared against arecoline purgation for the detection of echinococcus in naturally infected dogs in uruguay. the coproantigen elisa ha ... | 1995 | 7754606 |
| renal hydatid cyst: urinary cytological diagnosis. | echinococcal disease is endemic in many areas of asia, europe, south america, the near east, australia, and new zealand. hepatic and pulmonary cysts are the most common presentation. isolated renal hydatid cyst is an uncommon presentation of echinococcal disease, since renal involvement occurs in only 2-3% of cases. we present the case of a young man with renal colic, in whom the diagnosis of renal hydatid disease was established cytologically. urine cytology, performed because of persistent hem ... | 1995 | 7774496 |
| a defined antigen for the serodiagnosis of taenia ovis infections in dogs. | the evaginated scolex of taenia ovis secretes an antigen complex into defined culture medium that has been used to develop a cestode-specific enzyme-linked immunosorbent assay (elisa). we now describe an immunoblot test for antibodies to t. ovis based on the recognition of a 94-kda antigen band in the sodium dodecyl sulfate-polyacrylamide gel electrophoresis profile of t. ovis scolex secretions. the test was specific for cestode infections in dogs and was 82% sensitive for the recognition of t. ... | 1995 | 7776128 |
| characterisation of taeniid cestode species by pcr-rflp of its2 ribosomal dna. | seven species of taeniid cestode (echinococcus granulosus. e. multilocularis, taenia hydatigena, t. ovis, t. pisiformis, t. multiceps and t. serialis) were characterised using a polymerase chain reaction-based restriction fragment length polymorphism technique (pcr-rflp). the second internal transcribed spacer of ribosomal dna (its2) was amplified from various geographical isolates of each of the seven species, digested separately with four restriction endonucleases and the fragments were separa ... | 1995 | 7785524 |
| purification and partial immunochemical characterization of a low molecular mass, diagnostic echinococcus granulosus immunogen for sheep hydatidosis. | a hydatid specific antigen of 8 kda molecular mass was affinity-purified from crude hydatid cyst fluid. some of the epitopes recognised by antibodies in the sera from sheep with hydatidosis were periodate-sensitive. the purified 8 kda antigen was observed to be a thermo-stable glycoprotein in its immunochemical characteristics. by immunofluorescence on acetone-fixed protoscolices anti-8 kda monospecific igg antibodies indicated the existence of the 8 kda molecule on the hooklets of protoscolices ... | 1994 | 7804160 |
| immunoglobulin g subclass responses in human cystic and alveolar echinococcosis. | immunoglobulin g (igg) subclass-specific antibody responses were investigated in both human cystic echinococcosis (ce) and alveolar echinococcosis (ae) by enzyme-linked immunosorbent assay (elisa) and western blotting. sera were tested from 81 ce and 50 ae surgically confirmed cases using partially purified hydatid cyst fluid antigen b (egb), and crude hydatid cyst fluid (egcf) from echinococcus granulosus and a protoscolex extract (emp) prepared from e. multilocularis metacestodes. eighty-nine ... | 1994 | 7810806 |
| distribution of hydatidosis and cysticercosis in different peruvian populations as demonstrated by an enzyme-linked immunoelectrotransfer blot (eitb) assay. the cysticercosis working group in peru (cwg). | a serosurvey for human hydatidosis and cysticercosis was performed in different regions of peru. those regions included a known endemic area for cystic hydatid disease, a cooperative in the central peruvian andes near the city of tarma, department of junin; three areas endemic for cysticercosis in the departments of ancash, cuzco, and san martin, where the status of hydatid disease is not well defined; and an urban shantytown near lima, where neither zoonosis is known to be present. a seropreval ... | 1994 | 7810822 |
| migration of echinococcus granulosus via lymphatics. | 1995 | 7845147 | |
| modelling of parasitic populations: cestodes. | the philosophy of mathematical modelling as it applies to the epidemiology of cestode populations is reviewed. a model provides, via the "threshold theorem", a criterion for deciding in advance if a control programme can succeed in eradicating the parasite. in order to use this criterion it is necessary to have an estimate of the basic reproduction ratio, r0, which can only be obtained if reliable epidemiological data are available before the control programme is started. a model has been used t ... | 1994 | 7846848 |
| second recorded case of human infection by echinococcus oligarthrus. | the paper reviews a previously published case of hydatid disease in the human heart of a brazilian person who died of tetanus. based on present knowledge about the distinguishing characteristics of echinococcus granulosus, e. vogeli, and e. oligarthrus, it was recognized that the infection was due to e. oligarthrus, mainly based the morphologic features of the hooklets of the protoscolex. this is the second human infection due to e. oligarthrus and the first showing wall features of cysts. there ... | 1995 | 7856823 |
| in vitro production of cytokines by peripheral blood mononuclear cells from hydatid patients. | the role of cytokines in human hydatidosis (echinococcus granulosus infection) was evaluated in immunoassays determining production of il-4, il-10 and interferon-gamma (ifn-gamma) in peripheral blood mononuclear cell (pbmc) cultures from 30 hydatid patients and 14 uninfected controls. in cell cultures from hydatid patients parasite and non-parasite antigen stimulation significantly increased il-4 production (p < or 0.005). spontaneous and mitogen-driven il-4 production was similar in patients an ... | 1995 | 7882566 |
| isolation and biochemical characterisation of a glutathione s-transferase from echinococcus granulosus protoscoleces. | a protein fraction migrating as a m(r) 24 kda band on sds-page was isolated by affinity chromatography on glutathione-agarose from a soluble extract of e. granulosus proto-scoleces from sheep(uk). this fraction had glutathione s-transferase activity of 0.4 mumol min-1 mg-1 when measured using a standard synthetic substrate and its determined n-terminal amino acid sequence most closely resembled mu class glutathione s-transferases. in addition, protoscoleces from the distinct sheep and horse e. g ... | 1994 | 7883440 |
| echinococcus granulosus: the mechanism of oncosphere lysis by sheep complement and antibody. | a heat-labile component of normal sheep serum (56 degrees c for 30 min but not 50 degrees c for 30 min) was able to lyse oncospheres in vitro. the degree of effect, and the proportion of oncospheres lysed, was related to the concentration of normal unheated sheep serum complement, or other sources of complement (rabbit, mouse) in the culture. lower concentrations were required for lysis if the culture serum was obtained from sheep immune to e. granulosus infection. heat inactivation of normal or ... | 1994 | 7883443 |
| serodiagnosis and seroepidemiology of human unilocular hydatidosis in jordan. | a total of 2182 serum samples from 38 patients with surgically confirmed unilocular hydatidosis, 19 clinically assessed patients, 15 patients with parasitic infections other than hydatidosis, 104 hospital outpatients, and 2006 normal jordanians were serodiagnosed for the presence of igg antibodies against hydatid fluid, circulating immune complexes (cic), and/or hydatid circulating antigen (ca). anti-hydatid igg antibodies were detected in the sera of 77.4% of patients with hydatid disease and p ... | 1994 | 7886035 |
| identification of a cdna clone from the larval stage of echinococcus granulosus with homologies to the e. multilocularis antigen em10-expressing cdna clone. | 1994 | 7886043 | |
| hydatidosis in jordan: an epidemiological study of 306 cases. | of the 306 subjects studied, who had had hydatid cysts (echinococcus granulosus) surgically excised in jordan, 185 (60%) were female and 121 (40%) male. the liver was the most affected organ (57.8%), followed by the lung (26.4%). the kidneys, spleen, brain, soft tissues of neck, appendix and mesentery were less frequent sites. multiple-organ infection was seen in 23 patients (7.5%). over a third of the cases (35.8%) was aged < 21 years and the commonest occupation was housewife, followed by scho ... | 1994 | 7893176 |
| [rflp analysis of dna from echinococcus granulosus collected from four provinces/autonomous region in china]. | a fragment of the ribosomal rna gene of schistosoma mansoni psm889 and two dna fragments specific to echinococcus granulosus phd5 and peg18 have been used as dna probes to assess the extent of genetic variability within e. granulosus. the dna analysis, including restriction endonuclease digestion and southern blot hybridization with the probes, did not demonstrate any genetic variation among e. granulosus collected from sheep in xinjiang, qinghai, gansu and ninxia. similarly, there was no geneti ... | 1993 | 7909504 |
| a molecular genetic survey indicates the presence of a single, homogeneous strain of echinococcus granulosus in north-western china. | a combination of dna methods, including conventional rflp, pcr-rflp and mitochondrial sequence analysis did not detect genomic variation in any of 117 e. granulosus isolates examined from a range of intermediate hosts, including humans, in north-western china. the genotype infecting all hosts was indistinguishable from the widespread and well recognised sheep strain of e. granulosus. the public health implication of the study is that most, if not all, livestock infected with e. granulosus in thi ... | 1994 | 7911269 |
| molecular genetic characterization of the cervid strain ('northern form') of echinococcus granulosus. | we have used a number of molecular genetic approaches to characterize the cervid strain ('northern form') of echinococcus granulosus. pcr-rflp analysis of the nuclear its1 region of the rdna repeat can readily distinguish the cervid form from other strains of e. granulosus. the complexity of the rflp patterns obtained suggests that a number of distinct its1 types are present in this strain which may represent an inter-strain e. granulosus hybrid. mitochondrial co1 sequence of the cervid genotype ... | 1994 | 7916152 |
| further evaluation of autoreactive t cells in hydatid patients. | we evaluated the peripheral autoreactive response in patients with echinococcus granulosus who showed a negative humoral response as compared to seropositive patients and healthy controls. for this purpose, a limiting dilution analysis (lda) of autologous mixed lymphocyte cultures was established to both estimate frequency of autoreactive t cells and, by analysing the shape of the curves, to clarify the mechanisms that underlie the autoreactive response. different lda curves were observed betwee ... | 1994 | 7927515 |
| ultrastructure of oncosphere and early stages of metacestode development of echinococcus granulosus. | the ultrastructure of the oncospheres and developing metacestodes in vitro of echinococcus granulosus was studied with emphasis on the origin of the laminated layer. the activated oncospheres measured 28 microns (s.d. = 1.83), and by day 5 of in vitro culture the metacestodes attained diameters up to 52 microns (s.d. = 2.66). the oncospheral plasma membrane of the tegument appeared to be formed by a microtubular cytoskeleton arranged in a predetermined pattern. by day 2 there were three main typ ... | 1994 | 7928063 |
| purification and characterization of the alkaline phosphatase from echinococcus granulosus cyst membranes. | the purification to homogeneity and the characterization of echinococcus granulosus alkaline phosphatase (ap; ec 3.1.3.1) from hydatid cyst membranes are described. after n-butanol extraction, the parasite enzyme was sequentially purified by affinity chromatography on concanavalin a-sepharose followed by gel filtration. the purified protein (210 kda) had a tetrameric structure composed of 4 56-kda subunits. its isoelectric point (4.8) and its kinetic parameters were determined (km = 0.24 +/- 0.0 ... | 1994 | 7931900 |
| liver transplantation for echinococcus granulosus hydatid disease. | the authors report their experience with 6 patients requiring liver transplantation who suffered with liver infestation by echinococcus granulosus. one patient presented with acute budd-chiari syndrome because obstruction of hepatic veins was produced during the first operation; the other 5 patients received liver transplants for terminal chronic liver disease (2 secondary sclerosing cholangitis, 2 secondary biliary cirrhosis, and 1 postnecrotic cirrhosis of the liver). all the patients had been ... | 1994 | 7940713 |
| effects of benzimidazole compounds on mice infected with secondary cysts of echinococcus granulosus. | the effects of mebendazole (meb), albendazole (alb) and albendazole sulfoxide (albso) on metacestodes of echinococcus granulosus have been studied. the results show that meb and alb exhibit less effect on protoscoleces in vitro, but in vivo the protoscolicidal effect of meb is higher than that of alb. both meb and alb are efficacious in the treatment of mice infected with secondary cysts of e. granulosus. in terms of the minimal effective dose required, the occurrence of collapsed and shrunk cys ... | 1994 | 7956500 |
| a western blot and elisa assay for the diagnosis of taenia solium infection in pigs. | an enzyme-linked immunoelectrotransfer blot (eitb) was developed using soluble taenia solium metacestode antigen preparation for immunodiagnosis of porcine cysticercosis and compared with an enzyme-linked immunosorbent assay (elisa). sera from 20 pigs with parasitologically confirmed cysticercosis were tested by both eitb and elisa assays. specificity of the tests was examined by testing 25 serum samples from the uk, where cysticercosis is not endemic and sera from pigs with echinococcus granulo ... | 1994 | 7975116 |
| echinococcus granulosus infections in the dogs of kathmandu, nepal. | the prevalence, incidence and risk factors of infection by echinococcus granulosus were studied in the domestic and street dogs of kathmandu, nepal. using an elisa coproantigen test as a screening method, the highest prevalence (5/88 = 5.7%) was seen in domestic dogs from an area of the city used for slaughtering livestock. a prevalence of 1.8% (3/171) was found in domestic dogs seen at eight veterinary clinics distributed around the city. although none of the 73 street dogs sampled in the elisa ... | 1994 | 7979638 |
| [pulmonary echinococcosis, hepatic opisthorchiasis and generalized trichinelliasis combined with pregnancy]. | a case is reported of a spontaneous abortion (25 weeks of gestation) in a nenets woman resulting in thrombohemorrhagic syndrome and profuse uterine bleeding. the abortion is attributed to drastic allergization by three parasites: echinococcus granulosus, opisthorchis felineus, trichinella spiralis. | 1993 | 7980070 |
| expression and analysis of the diagnostic value of an echinococcus granulosus antigen gene clone. | a pool of 9 sera from echinococcus granulosus infected patients (psp) was used to screen an e. granulosus cdna library constructed in the expression vector lambda gt11. ten reactive phage clones were isolated and 8 were confirmed in spot-lysis arrays probed with psp. the insert of 1 of these clones (lambda ageg4) previously characterized as an e. granulosus cytosolic malate dehydrogenase encoding gene was subcloned into the plasmid vector pgex-1 and expressed as a fusion with glutathione s-trans ... | 1994 | 7982748 |
| hydatid liver disease: a perspective in treatment. | hydatid liver disease caused by echinococcus granulosus is a serious problem in regions where the parasite is endemic. the treatment of choice is surgery, however, it is associated with recurrence rates of up to 30%. medical treatment with benzimidazole derivatives has limited success. the treatment modalities for hydatid liver disease are reviewed in detail and are evaluated in terms of radical treatment. | 1994 | 7988062 |
| the development of new foci of echinococcosis in northern israel: prevalence in domestic animals. | in a survey carried out in 1991-1992 in the town of yirka in northern israel, 49 dogs were examined for echinococcus granulosus infection and abattoir data, based on organs condemned for the presence of parasites, was collected. the presence of e. granulosus by arecoline test was demonstrated in 7 (14.2%) of the dogs examined, but not parasites were found in the intestines of five stray dogs shot in the area. a survey of sheep slaughtered in the local abattoir during a one-month period revealed ... | 1994 | 8006384 |
| effects of mebendazole, albendazole, and praziquantel on fumarate hydratase, pyruvate kinase, and phosphoenolpyruvate carboxykinase of echinococcus granulosus cyst wall harbored in mice. | echinococcus granulosus cyst wall exhibited activities of fumarate hydratase (fh), pyruvate kinase (pk), and phosphoenolpyruvate carboxykinase (pepck) with 911-1433, 151-215, and 54-98u, respectively. the ratio of pk/pepck was 2.2-2.7, indicating that glycolysis is the main pathway of carbohydrate metabolism in the cyst wall. when infected mice were treated ig with mebendazole, albendazole or praziquantel at the respective daily dose of 25-50, 300, and 500 mg.kg-1 for 7-14 d, no apparent change ... | 1994 | 8010090 |
| [experimental chemotherapy of echinococcosis. 13. the effect of mebendazole in combination with a vegetable oil on the larval cysts of echinococcus multilocularis and the reaction of the infested host to long-term administration of the preparation]. | the use of mebendazole as a suspension in vegetable oil enhanced the efficiency of treating experimental echinococcus granulosus infection in outbred albino rats without increasing the dose of the drug. a sharp reduction in platelet count in the blood of the infected animals treated and untreated suggests that thrombohemorrhagic complications might be in echinococcosis. thrombopenia in the treated animals appeared to be steady-state. a decrease in a rapid immune response in the mebendazole-treat ... | 1994 | 8015518 |
| case report 833: primary spinal echinococcosis (echinococcus granulosus) of lumbosacral spine with destruction of the left pedicles of l3-5 and extension of a large paraspinal cystic mass into the spinal canal. | ct is helpful in recognizing the occurrence of hydatid cysts. the increased spatial resolution allows better visualization of details of bone destruction and spinal canal involvement. paraspinal cystic disease may also show typical and/or characteristic signs of hydatid disease even if serological findings are falsely negative or inconclusive. in the postoperative follow-up, ct may be helpful in assessing residual hydatid cysts and/or in detecting recurrence at an earlier stage. | 1994 | 8016676 |
| the effects of albendazole and albendazole sulphoxide combination-therapy on echinococcus granulosus in vitro. | protoscoleces of echinococcus granulosus were incubated in vitro with decreasing concentrations of either albendazole (abz) or albendazole sulphoxide (abz.so) (50, 10, 1 and 0.1 micrograms ml-1), and in combination. viability was assessed by the methylene blue exclusion test and establishment of infection in mice. protoscolex ultrastructure was determined by means of transmission and scanning electron microscopy. abz and abz.so, when used separately had protoscolicidal activity after a longer in ... | 1994 | 8026899 |
| intestinal helminth parasite community in wolves (canis lupus) in italy. | from 1987 to 1993, 89 wolves (canis lupus) collected throughout the whole italian range were examined for intestinal helminth parasites. twelve species were found, including 5 nematodes (uncinaria stenocephala, toxocara canis, ancylostoma caninum, trichuris vulpis and toxascaris leonina) and 7 cestodes (echinococcus granulosus, taenia hydatigena, t. multiceps, t. pisiformis, t. ovis, mesocestoides lineatus and dipylidium caninum). no significant differences were detected between sexes. t. canis ... | 1993 | 8065823 |
| the random amplification of polymorphic dna can discriminate species and strains of echinococcus. | the random amplified polymorphic dna-polymerase chain reaction (rapd-pcr), also called arbitrary priming pcr (ap-pcr), is a dna polymorphism assay based on the amplification of genomic dna using a single oligonucleotide primer of arbitrary nucleotide sequence. using carefully controlled conditions, the random amplified polymorphic dna-polymerase chain reaction (rapd-pcr) proved useful for distinguishing echinococcus species and genetically distinct strains of echinococcus granulosus. amongst twe ... | 1994 | 8066374 |
| development of truncated microtriches in echinococcus granulosus protoscolices. | the development of truncated microtriches in the somatic region of both (a) protoscolices incubated in vitro with two different drugs, i.e. ivermectin or a combination of albendazole and albendazole sulphoxide, and (b) protoscolices removed from hydatid cysts in humans treated with albendazole for 1.5 months is described. our findings seem to indicate that the development of microtriches is either an indirect effect of treatment with anthelmintics or a possible response to other, as yet unidenti ... | 1994 | 8073026 |
| deoxyribonuclease activity in echinococcus granulosus protoscoleces and hydatid fluid. | deoxyribonuclease activity was detected in e. granulosus protoscoleces from sheep hydatid cysts by electrophoresis in agarose gels of dna fragments obtained after incubation of integral dna with a protoscoleces preparation. preliminary characterization showed that deoxyribonuclease activity was optimal at neutral-alkaline ph, magnesium ions were required, and it was able to digest different types of dna, making random cuts. electrophoresis in dna-containing sodium dodecylsulfate (sds)-polyacryla ... | 1994 | 8082990 |
| immunocytochemical localization of serotonin (5-ht) in the nervous system of the hydatid organism, echinococcus granulosus (cestoda, cyclophyllidea). | the localization and distribution of the serotoninergic components of the nervous system in the hydatid organism, echinococcus granulosus, were determined by immunocytochemical techniques in conjunction with confocal scanning laser microscopy (cslm). the distribution of serotonin immunoreactivity (ir) paralleled that previously described for cholinesterase activity, although it was more widespread. nerve cell bodies and nerve fibres immunoreactive for 5-ht were present throughout the central ner ... | 1994 | 8084668 |
| comparative genetic analysis of swiss and spanish isolates of echinococcus granulosus by southern hybridization and random amplified polymorphic dna technique. | swiss and spanish isolates of echinococcus granulosus were compared using different molecular biological techniques: genomic dnas isolated from parasites originating from various intermediate hosts were subjected to southern hybridization with different probes, the same source of dna was used for dna amplification using the random amplified polymorphic dna (rapd) technique. with both methods the various isolates (metacestodes) of e. granulosus exhibited characteristic banding patterns which allo ... | 1994 | 8087150 |
| rapid discrimination of echinococcus species and strains using a polymerase chain reaction-based rflp method. | echinococcus species and genetically distinct strains of echinococcus granulosus can be rapidly and reliably identified using a polymerase chain reaction (pcr)-linked restriction fragment length polymorphism (rflp) method which surveys the sequence of a rapidly evolving region of the ribosomal dna (rdna) unit. internal transcribed spacer 1 (its1) of the rdna repeat was amplified from various isolates and the product was digested with one of a number of 4-base cutting restriction enzymes. charact ... | 1993 | 8094539 |
| molecular examination of the sympatry and distribution of sheep and camel strains of echinococcus granulosus in kenya. | previous studies have shown that camel and sheep strains of the cystic hydatid parasite echinococcus granulosus occur in kenya. we examined 208 larval isolates and 40 worm samples of e. granulosus from various hosts in kenya using restriction fragment length polymorphism analysis of a segment of ribosomal dna amplified by the polymerase chain reaction. this was in an effort to determine whether additional strains of e. granulosus occur in kenya, to examine the level of genetic heterogeneity with ... | 1993 | 8097619 |
| host influence on the rate of maturation of echinococcus granulosus in dogs in kenya. | 1993 | 8122923 | |
| nmr and circular dichroic studies of the solution structure of conformationally constrained antigenic peptides. | circular dichroic and nuclear magnetic resonance spectroscopies were used to evaluate the conformational properties in solution of a series of 20-amino-acid peptides derived from the primary structure of an antigen from echinococcus granulosus. the linear peptide corresponding to the sequence 93-112 in the antigen was found to populate in a significant proportion the alpha-helix conformational state. in the presence of 2,2,2-trifluoroethanol, a cosolvent known to stabilize peptide secondary stru ... | 1994 | 8125099 |
| [human echinococcosis: the role of histocompatibility antigens in realizing infestations and the characteristics of their course]. | the role of histocompatibility antigens in the realization of invasions and the nature of its course were studied in 71 patients with echinococcus granulosus infection and in 18 with e. multilocularis infection. it has been shown that the effects of hla antigens on the realization of invasion is heterodirectional; the factors predisposing to the occurrence of echinococcosis are hla-b5, b18, and a28 antigens, whereas those preventing their realization are hla-b14 antigen. the carriage of hla-b5 a ... | 1993 | 8127263 |
| primary infection of dogs with echinococcus granulosus: systemic and local (peyer's patches) immune responses. | local and systemic lymphocyte proliferation and antibody production were tested in five dogs 35 days after primary experimental infection with echinococcus granulosus. a significant cell proliferation was demonstrated by [3h] thymidine incorporation in mesenteric, popliteal and/or peyer's patches (pps) cells in response to e. granulosus protoscolex or adult worm antigen in three of five infected dogs, but not in five control animals. in contrast, blood mononuclear cells responded very weakly in ... | 1994 | 8160357 |
| [characterization of echinococcus granulosus and echinococcus multilocularis by dna probe]. | cloned dna fragments phd5, psm889 and peg18 have been used as dna probes in the restriction endonuclease analysis and southern blot hybridization to characterize e. granulosus and e. multilocularis protoscolices from china. southern blot hybridization method is sensitive, specific and has the advantage in identification over microscopic examination. the authors deem that it can be used in the base-line epidemiological survey and surveillance of hydatid disease to provide data for hydatid disease ... | 1993 | 8168243 |
| hyperendemic focus of echinococcosis in north-eastern victoria. | to establish the prevalence of echinococcosis in feral canids in a region in the north-east of victoria (tallangatta) and assess its potential public health significance in this region. | 1994 | 8170426 |
| metacestodes of sheep with special reference to their epidemiological status, pathogenesis and economic implications in fars province, iran. | this study was undertaken over a period of 2 years. of 7992 sheep examined, 2088 (26.12%), 2266 (28.36%), 15 (0.19%) and 738 (9.8%) were infected with echinococcus granulosus, taenia hydatigena, taenia ovis and taenia multiceps metacestodes, respectively. the prevalence was higher in animals belonging to migratory tribal people than in those owned by the permanent residents of fars province. dogs in the former group also showed significantly higher levels of infection with e. granulosus (33.3%) ... | 1994 | 8171825 |
| intestinal helminths of public health importance in dogs in nairobi. | in a survey of intestinal canine zoonotic helminths in nairobi, 156 dogs were autopsied. of these, 10% were infected with echinococcus granulosus, 88% with ancylostoma caninum, 45% with dipylidium caninum and 3% with toxocara canis. all the infected dogs with e. granulosus originated from around abottoirs in dagoretti. the risk of infection in man with hydatid disease is considered to be high around dagoretti and control measures are recommended. | 1993 | 8187655 |
| us case of the day. hydatid cyst (echinococcus granulosus) in the right lobe of the liver. | 1994 | 8190968 | |
| echinococcus granulosus: characterization of the electrical potential of the syncytial tegument of protoscoleces incubated in vitro--effect of inhibitors. | upon microelectrode impalements of the tegument of echinococcus granulosus protoscoleces incubated in ringer krebs solution, electrical potential differences of -49 +/- 1 mv, using procedure i, and -53 +/- 1 mv, using procedure ii, were recorded. the changes in the electrical potential difference as well as the structural alterations produced by sodium deoxicholate indicate that the observed potentials are established across the apical membrane of the syncytial tegument. the electrical potential ... | 1994 | 8206139 |
| high performance latex reagent for hydatid serology using an echinococcus granulosus lipoprotein antigen fraction purified from cyst fluid in one step. | a lipoprotein fraction from fertile bovine hydatid cyst fluid (fbhcf) was isolated by affinity chromatography on acrylic-heparin. the heparin-binding lipoprotein fraction (hblf) was proved to be free from host immunoglobulins and albumin. immunoblotting with confirmed human hydatid sera showed that the major relevant diagnostic bands in fbhcf were also present in hblf. hblf or fbhcf were used to sensitize polystyrene latex particles. hblf-latex showed both higher reactivity with positive hydatid ... | 1993 | 8225758 |
| epidemiology of hydatidosis and echinococcosis in theqar province, southern iraq. | ninety-six cases of human hydatidosis caused by echinococcus granulosus were diagnosed from surgical records of hospitals in theqar province, southern iraq during 1989. the infection rate was higher in female than in male patients (56 versus 40 cases) and increased with their age (maximum, 25.0% in a female group of 31-40 years and 32.5% in a male group of 41-50 years). many organs such as liver, lungs, peritoneum and spleen were involved, but the liver was most frequently affected. of 96 patien ... | 1993 | 8230806 |
| molecular cloning and characterization of actin genes from echinococcus granulosus. | an echinococcus granulosus genomic library has been screened with a mouse beta-actin cdna probe. two clones carrying dna fragments of about 15 kb, possibly derived from the same genome region, have been isolated. this 15-kb genomic region includes 2 actin-related sequences (egacti and egactii) separated by about 4 kb. the nucleotide sequences of both genes were determined. the egacti sequence presents no introns, but an intron of 591 bp was observed in the egactii sequence. the genes potentially ... | 1993 | 8232413 |
| ultrastructural localization of major hydatid fluid antigens in brood capsules and protoscoleces of echinococcus granulosus of human origin. | monospecific rabbit antisera obtained through experimental immunization with previously purified proteins were used in the ultrastructural localization of two hydatid fluid antigens, in brood capsules and protoscoleces of echinococcus granulosus of human origin. the antigen-antibody reaction was revealed by a colloidal gold based method. reaction was evident in the connective region of the germinal membrane and in the parenchyma of the protoscoleces. both antigen 5 and antigen b were located in ... | 1993 | 8233559 |
| igg subclasses in human hydatid disease: prominence of the igg4 response. | to assess the participation of the four subclasses of igg in the humoral response to echinococcus granulosus infection, we determined total and parasite-specific igg1, igg2, igg3 and igg4 in sera from 46 patients with hydatid disease using an enzyme-linked immunosorbent assay (elisa). parasite-specific igg subclass antibodies were quantitatively measured by means of standard curves obtained by affinity chromatography. sera from 35 healthy individuals served as controls. the total component of ig ... | 1993 | 8241797 |
| dose-dependent effects of hydatid fluid toxins from echinococcus granulosus on mouse peritoneal macrophages. | hydatid fluid (hf) from hydatid cysts of the cestode echinococcus granulosus inhibited the phagocytosis of bacteria and yeast cells by host macrophages in vitro. different assays were used to study the dose-dependent effect of partially purified hf toxins on peritoneal macrophages (pm phi) of the mouse. trypan blue exclusion, as well as measuring the specific release of lactate dehydrogenase activity and 51cr release of 51cr-labelled pm phi, showed that incubation with hf toxins lead to the lysi ... | 1993 | 8244205 |
| echinococcal disease. | diagnosis of infection by the larval stages of echinococcus granulosus, e. multilocaris, and e. vogeli, has increased in most parts of the world because of improved diagnostic technology, active surveillance, and increasing rates of transmission. specific immunodiagnostics and sophisticated imaging techniques have made diagnosis more sensitive and specific. surgery, performed by an experienced team with adequate postoperative support, remains the mainstay of therapy; however, alternative treatme ... | 1993 | 8254162 |
| albendazole therapy of hydatid disease: 2-year follow-up of 40 cases. | forty patients with 63 echinococcus granulosus cysts affecting different sites were treated with albendazole and have been followed up for at least 24 months from completion of therapy. twenty-one patients (53%) with 37 cysts (59%) showed evidence of healing. the criteria and pattern of healing are outlined. the most serious complication of albendazole therapy was hepatoxic jaundice, which occurred in 5% of patients. recurrence during the observation period was encountered in 9.5% of patients wi ... | 1993 | 8257234 |
| focal liver lesions. evaluation of simple and complex cysts. | ultrasound is often the first imaging study used to determine the nature of focal liver lesions. although simple cysts often need no treatment, those large enough to compress or to irritate adjacent structures should be surgically unroofed and drained. complex liver cysts may be caused by bacteria, amebae, or tapeworms (echinococcus granulosus). rarely, neoplasms present as cystic lesions and need further study for definitive diagnosis. | 1994 | 8278296 |
| studies on echinococcus granulosus using the scanning electron microscope. i. preparations of the parasite for infection of the final host. | the development of the protoscoleces of echinococcus granulosus was studied after chemical stimulation, which mimics that offered by the final host. this stimulation resulted in some morphological changes in the parasite and to its evagination. these changes prepare the parasite to infect the intestine of its final host. the external morphology of the protoscolex body and of the germinal layer of the cyst and brood capsule were studied using the scanning electron microscope (sem). findings were ... | 1993 | 8278334 |
| studies on echinococcus granulosus using the scanning electron microscope. ii. the hooks. | the morphology of the hooks of echinococcus granulosus at the protoscolex level was studied by means of scanning electron microscopy. hooks were uncovered in situ and also freed from the rostellum so as to study them in detail. there were two types of hooks: those of the upper row, which were larger and had a projecting, rounded stout guard, and those of the lower row, which were smaller and had a flattened guard. these and other differences in the morphology of the two types of hooks were studi ... | 1993 | 8278335 |
| [hydatidosis immunodiagnosis: determination of taenia crassiceps cysticerws antigens in hydatid and vesicular fluid]. | the specificity and sensitivity of the enzyme immunoassay (eia), presently used in south america areas where hydatidosis caused by echinococcus granulosus is endemic, was compared to two alternative eia. one of these uses an hydatid antigen of different preparation and the other vesicular fluid of taenia crassiceps cisticerci (vfcc). the effect of previous neutralization in the serum sample of antibodies antinormal ovine or murine sera and antiphosphorylcholine on the diagnostic efficiency of th ... | 1993 | 8284600 |
| some observations on hydatidosis in jordan. | a total of 2.8% (5 of 176) sera from schoolchildren and university students were seropositive for hydatidosis (echinococcus granulosus), by the elisa ige test. the prevalence of seropositivity was 4.5% among females of all age groups (5-24 years) and among males of the age group 18-24 years. males of the age group (5-17 years) were seronegative. the ratio of seropositivity between schoolboys and schoolgirls was 1:4. sera collected from 1085 university students, aged 18-24 years, and from 1656 ou ... | 1993 | 8288858 |
| paramyosin of echinococcus granulosus: cdna sequence and characterization of a tegumental antigen. | a lambda zapii cdna library of echinococcus granulosus larvae was expressed in escherichia coli sure cells. screening of the library with a rabbit antiserum raised against total larval antigen yielded several immunoreactive clones. for analysis of the nucleotide sequence, in vivo excision into pblueskript was carried out and the 3' end of the cloned insert was sequenced. three of these clones exhibited identical nucleotide sequences, suggesting expression of identical genes. the complete nucleot ... | 1993 | 8295903 |
| cystic hydatid lung disease in northwest canada. | to determine the optimal treatment of sylvatic cystic hydatid lung disease. | 1994 | 8306214 |
| serological differentiation between cystic and alveolar echinococcosis by use of recombinant larval antigens. | two recombinant antigens of the larval stages of echinococcus granulosus and echinococcus multilocularis, termed eg55 and em10, respectively, were applied for serodiagnosis and serological differentiation between parasitic infections caused by the metacestode tissue of both tapeworms. antigen em10 is synthesized by e. multilocularis larvae. antigen eg55 represents the recombinant form of the low-molecular-weight subunit of antigen b, which is an echinococcus genus-specific antigen. both recombin ... | 1993 | 8308113 |
| echinococcus granulosus (taeniidae) and autochthonous echinococcosis in a north american horse. | we report the first documented case of autochthonous echinococcosis in a horse of north american origin. three fully mature and viable unilocular hydatid cysts of echinococcus granulosus (batsch, 1786) were an incidental finding at necropsy in the liver of a 14-yr-old gelding thoroughbred that had been foaled in virginia and raised in maryland. protoscolices were armed with 2 rows of 28-37 rostellar hooks; small hooks measured 23-30 microns; large hooks measured 26-33 microns. morphologically, t ... | 1994 | 8308647 |
| giant hydatid lung cysts in the canadian northwest: outcome of conservative treatment in three children. | hydatid lung disease due to echinococcus granulosus in the canadian northwest and alaska is often asymptomatic and usually benign. we reviewed the course and outcome of three children with giant hydatid lung cyst seen over a 2-year period. all were north american indian children aged 9 to 12 years who presented with cough, fever, and chest pain. one had a rash. there was a history of exposure to domestic dogs who had been fed moose entrails in each case. chest x-rays showed solitary lung cysts w ... | 1993 | 8308679 |
| random amplified polymorphic dna technique for speciation studies of echinococcus granulosus. | 1993 | 8327458 | |
| heart transplantation in a patient with liver hydatidosis. | the human can serve as an accidental intermediate host to echinococcus granulosus, a parasite that targets dogs as its definitive hosts. we present the case of a 27-year-old man with liver hydatidosis, who underwent heart transplantation because of ischemic cardiomyopathy. the immunosuppressor treatment had no effect on the size of the cysts, which were removed surgically 14 months after heart transplantation; good results persist after 3 years of follow-up. | 1993 | 8329434 |
| isolation and characterization of a middle repetitive dna element from echinococcus granulosus. | 1993 | 8341331 | |
| the potential of vervet monkeys (cercopithecus aethiops) and baboons (papio anubis) as models for the study of the immunology of echinococcus granulosus infections. | nine vervet monkeys and nine baboons were infected with eggs of echinococcus granulosus per os. six of the vervets and one of the baboons possessed hydatid cysts at autopsy, 15-28 months post-infection. the sequential igg response to hydatid fluid and protoscolex antigens showed considerable inter-animal variation. infected vervets and baboons became seropositive after an average of 8 months post-infection. considerable fluctuation in the igg response was observed, particularly to the hydatid fl ... | 1993 | 8341587 |