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serum and cerebrospinal fluid concentrations of rifampicin at two dose levels in children with tuberculous meningitis.twenty patients of tuberculous meningitis (tbm) in age group of 6 months to 10 years included in the study were divided into two groups of 10 patients each. rifampicin was administered in dosage of 10 mg and 7.5 mg/kg bw to each patient of groups i and ii respectively. drug concentrations in serum and csf of these patients were measured by a microbiological tube dilution method using a strain of sarcina lutea. in group i mean serum and csf concentration was 3.84 micrograms/ml and 0.178 microgram ...19979465533
antimicrobial effects of aqueous plant extracts on the fungi microsporum canis and trichophyton rubrum and on three bacterial species.aqueous extracts of 10 plants were tested for their ability to inhibit trichophyton rubrum and microsporum canis, the aetiological agents of dermal fungal infections in humans. these extracts were also evaluated for their activity against some bacteria. aqueous extracts from the leaves of inula viscosa produced detectable antifungal activity against these dermatophytes.19989489036
the mitochondrial phosphoglyceroyl-atp-containing polymer, purinogen, is unchanged by cardiac ischaemia and reperfusion but may function in the regulation of free intracellular inorganic phosphate concentrations.previous work in our laboratory demonstrating large unexplained systematic variations in the heart contents of free adenine nucleotides led us to propose the existence of some unrecognised sequestered form and thence to the purification of very labile acid-insoluble oligomers which we characterised as oligo[3-phospho-glyceroyl-gamma-triphospho(5')adenosine(3')] , abbreviated to (pg-atp)n. more recently, we provided evidence that these oligomers appear to be the end chains of a complex polymer lo ...19989652397
attachment of the chromosome to the cell poles: the strategy for the growth of bacteria in two and three dimensions.bacteria such as staphylococcus, lampropedia, and sarcina develop in characteristic two-or three-dimensional groups of cells. we propose here a model of how bacteria may generate such groupings by an extension of an earlier model for rod-shaped bacteria. no other mechanism for forming two- or three-dimensional structures of groups of cells has been proposed. our earlier model for division of rod-shaped bacteria into nearly equal-sized daughters assumed that the origin and terminus dna were attac ...199910395815
antimicrobial activity and stability of tingenone derivatives.quinone-methide triterpenes of the tingenone series were evaluated for their antimicrobial activity. these compounds were effective against bacillus cereus, b. subtilis, sarcina lutea, staphylococcus aureus, microsporum gypseum and a gram-negative bacterium, klebsiella pneumoniae. under acidic conditions, the quinone-methide part of these compounds rearranged into the divinyl-phenolic system, and the antimicrobial activity was thus lost.199910418334
bacteriological studies of blood, tissue fluid, lymph and lymph nodes in patients with acute dermatolymphangioadenitis (dla) in course of 'filarial' lymphedema.filarial lymphedema is complicated by frequent episodes of dermatolymphangioadenitis (dla). severe systemic symptoms during attacks of dla resemble those of septicemia. the question we asked was whether bacterial isolates can be found in the peripheral blood of patients during the episodes of dla. out of 100 patients referred to us with 'filarial' lymphedema 14 displayed acute and five subacute symptoms of dla. all were on admission blood microfilariae negative but had a positive test in the pas ...199910546838
absorption kinetics and bioavailability of cephalexin in the dog after oral and intramuscular administration.the pharmacokinetics of cephalexin, a first generation cephalosporin, were investigated in dogs using two formulations marketed for humans, but also often employed by practitioners for pet therapy. cephalexin was administered to five dogs intravenously and intramuscularly as a sodium salt and by the oral route as a monohydrate. the dosage was always 20 mg/kg of active ingredient. a microbiological assay with sarcina lutea as the test organism was adopted to measure cephalexin concentrations in s ...199910597534
sarcina -like bacteria, clostridium fallax and clostridium sordellii in lambs with abomasal bloat, haemorrhage and ulcers.a study of abomasal disease in lambs aged 2-5 weeks, made during the period 1993-1998, included 67 cases and 45 non-affected controls. gross pathological findings included various combinations of bloat, haemorrhage and ulcers in the abomasum. sarcina -like bacteria were found in sections and smears from the abomasum of 79% (53/67) of the cases. from one case, a lamb with abomasal bloat, the anaerobic "packet"-forming sarcina ventriculi was cultivated from the abomasal contents and identified by ...200010684688
metabolites of colletotrichum gloeosporioides, an endophytic fungus in artemisia mongolica.a new antimicrobial metabolite, named colletotric acid (1), was isolated from a liquid culture of colletotrichum gloeosporioides, an endophytic fungus colonized inside the stem of artemisia mongolica. the structure was determined using spectroscopic methods (eims and fabms,(1)h and (13)c nmr, (1)h-(1)h cosy, hmbc, and hmqc). compound 1 inhibited the growth of bacillus subtilis, staphylococcusaureus, and sarcina lutea with minimal inhibitory concentrations (mics) of 25, 50, and 50 microg/ml, resp ...200011087599
possible involvement of sarcina ventriculi in canine and equine acute gastric dilatation. 200011126583
studies on aminopyrazoles: antibacterial activity of some novel pyrazol.hydrazones 2a-d were prepared from diazotiazation of sulfanilamide or its derivatives followed by coupling with ethyl cyanoacetate. 3-aminopyrazoles 3a-d were obtained by refluxing of 2a-d with hydrazine hydrate in ethanol. [bis(-methylthio)methylene]malononitrile (4) was reacted with aminopyrazoles 3a-d in refluxing dmf containing triethylamine to yield the novel pyrazolo[1,5-a]pyrimidines 6a-d. the anilino derivatives 8a-h were obtained by fusion of compounds 6a-d with aromatic amines. when co ...200011152240
lactic acid bacteria from healthy oral cavity of thai volunteers: inhibition of oral pathogens.the aims of the present study were to screen and characterize the antimicrobial lactic acid bacteria which were isolated from healthy oral cavities of thai volunteers, and to characterize their inhibiting substances. among 3790 isolates (suspected to be lactic acid bacteria) from 130 volunteers, five showed an appreciable effect against sarcina lutea atcc 9341, bacillus cereus atcc 11778, escherichia coli atcc 25922, staphylococcus aureus atcc 6538, streptococcus mutans dtmu 1, strep. salivarius ...200111168719
methylosarcina fibrata gen. nov., sp. nov. and methylosarcina quisquiliarum sp.nov., novel type 1 methanotrophs.two novel species of obligate methane-oxidizing bacteria, isolated from landfill soil, were characterized. both strains were unusual in that some members of the population grew in irregularly shaped, refractile cell packets that resembled sarcina-like clusters. electron microscopy revealed that the cell packets were covered with a slime layer and the cells contained many large granular inclusion bodies. the individual cells of each strain were sometimes motile and had differing morphologies. iso ...200111321107
production of the gram-positive sarcina ventriculi pyruvate decarboxylase in escherichia coli.sarcina ventriculi grows in a remarkable range of mesophilic environments from ph 2 to ph 10. during growth in acidic environments, where acetate is toxic, expression of pyruvate decarboxylase (pdc) serves to direct the flow of pyruvate into ethanol during fermentation. pdc is rare in bacteria and absent in animals, although it is widely distributed in the plant kingdom. the pdc gene from s. ventriculi is the first to be cloned and characterized from a gram-positive bacterium. in escherichia col ...200111535783
ultra-high vacuum and microorganisms.experimental study of the space environment effect on living organisms is one of the most important tasks of exobiology. however location of the living organisms under study outside space vehicles and sputniks is combined with technical difficulties. therefore it is much more suitable to reproduce conditions found in space in laboratory and to study its effect on living cells. it was proved that low temperatures, even those approaching absolute zero do not kill microorganisms. the fact of microo ...196512035798
female genital tissue concentrations of roxithromycin.a new macrolide, roxithromycin, appears to have some interesting pharmacokinetic characteristics dissimilar to those of erythromycin, e.g. it has the unusual property of a long serum half-life and the possibility of once daily dosing. moreover tissue levels are higher than those obtained with other macrolides, and the drug is still present in the tissues up to 24 h. after dosing. the pharmacokinetics of roxithromycin were studied in 36 women undergoing gynecological surgery, and divided by means ...199112041780
screening of eight alkaloids and ten flavonoids isolated from four species of the genus boronia (rutaceae) for antimicrobial activities against seventeen clinical microbial strains.eight alkaloids and ten flavonoids isolated from four species of boronia of the rutaceae were screened against 17 clinical microbial strains. of the test compounds, three acridone and one quinolone alkaloids and eight flavonoids were reported as novel natural products. screening was carried out by the standard disc diffusion method. of the tested compounds, six alkaloids and seven flavonoids including the novel products were active against six clinical strains. the active compounds showed mild t ...200212410551
the effect of high vacuum on oxidative reactions in bacteria and the activity of certain enzymes.among the physical factors which might influence micro-organisms one of the most potentially interesting is high vacuum. the effect of high vacuum is less studied as compared with other physical factors. it is impossible to achieve, under laboratory conditions, a vacuum of the order 10(-16) mm hg which is probably characteristic of space. earlier, the effect of high vacuum was studied on different bacteria, yeasts, molds and algae. it appeared that spores and fungal conidia were not killed by hi ...197012664921
conventional morphological and functional evaluation of the microbial populations in a sequencing batch reactor performing ebpr.to help confirm and interpret the enhanced biological phosphorus removal (ebpr) performance of the microbial populations in a laboratory-scale activated sludge (as) system, conventional microscopic examinations were carried out. a lab-scale sequencing batch reactor (sbr), named arc, was fed with acetate, as the sole carbon source, and operated for ebpr. daily monitoring and cyclic behavior evaluation studies indicated that the system always worked for ebpr in the long run, with efficiencies depe ...200312929804
on an antibiotic, sarcidin, produced by streptomyces n. sp. s. achromogenes. 195313061372
[examination of microorganisms for carcinogenic effect]. 195313105313
the international standard for aureomycin.in 1950, the department of biological standards, national institute for medical research, london, was authorized by the who expert committee on biological standardization to proceed with the establishment of an international standard for aureomycin. a 100-g batch of aureomycin was obtained and was compared with the standard preparation of aureomycin of the united states food and drug administration (fda) in a collaborative assay in which six laboratories in five countries participated.in all, 30 ...195313141137
[filtrable forms of sarcina lutea]. 195313144395
action of hyaluronidase and lysozyme on sarcina flava. 195413159335
[bacteriolytic activity of sarcina lutea]. 195313171046
the effect of lysozyme on the electrophoretic mobility of certain cocci. 195413173483
wavelengths of bacterial flagella. 195413174768
[technical considerations on the determination of magnamycin]. 195413189204
growth requirements for a penicillin sensitive sarcina lutea. 195413201540
[ortho-diphenol requirements of coccus p (sarcina sp.) for growth]. 195613304073
the nucleic acids of sarcina lutea. 195613306900
[characteristics of synthesis of carotenoids in sarcina lutea]. 195613321526
[kinetic study of the lysis of sarcina lutea by lysozyme]. 195613323648
some biochemical changes accompanying penicillin inhibition of sarcina lutea. 195613357452
liberation and osmotic properties of the protoplasts of micrococcus lysodeikticus and sarcina lutea. 195613385434
[mechanism of lysis of coccus p (sarcina flava) by lysozyme]. 195713395054
sarcina lutea plate assay of novobiocin. 195613425500
[alleged extraction of protoplasts from micrococcus lysodeikticus and sarcina lutea by controlled action of lysozyme]. 195713447331
[nature and significance of bacteriophagia. x. study of the characteristics of symbiotic action of sarcina by means of a quick motion camera microphotography]. 195713457233
[study on the proteinase of coccus p. (sp. sarcina flava). i. purification]. 195713460606
controlling growth of test bacteria for antibiotic assays through anaerobiosis. 195713467289
[kinetics of the specific phase of coccus p (sp. sarcina flava) lysis by lysozyme; ionic influences]. 195713472331
[taxonomy of micrococcus lysodeikticus and coccus p; contingent secretion of proteinase in certain species of the genus sarcina]. 195713478933
[the proteinase of coccus p (sp. sarcina flava). ii. solubility characteristics]. 195713511005
the assay of penicillin in blood-serum using sarcina lutea.when sarcina lutea is used as test organism in a cup-plate assay, the dose-response curves for the assay of penicillin in sera of humans and rabbits are linear with the square of the zone diameter and log concentration of penicillin and parallel to the dose-response curve for penicillin in phosphate buffer. suitable conditions for such assays are described, using either large square assay-plates and fish-spine beads or conventional petri dishes and cylinders. the assay using large plates and fis ...195713511134
a correlation between the structure of neomycin b and its action on bacteria. 195813513582
metabolism of sarcina lutea. i. carbohydrate oxidation and terminal respiration. 195813525341
[growth and development of bacteria and their relation to the phenomenon of bacteriophage. iii. symbiosis of organisme as a factor inducing bacterial phage production]. 195813535849
[study on the proteinase of coccus p. iii. specificity]. 195813546872
[experiments with the filtrable forms of sarcina flava]. 195813551253
metabolism of sarcina lutea. ii. isotopic evaluation of the routes of glucose utilization. 195813560449
studies on a radiation-resistant pigmented sarcina sp. 195813579188
sugar decomposing activity of sarcina flava in certain phases of its life cycle. 195813594272
[influence of some medical plants and substances on sarcina lutea with the aim of using them as carcinolytic agents; preliminary report]. 195813603210
metabolism of sarcina lutea. iii. endogenous metabolism. 195813607444
studies on sarcina ventriculi. iii. localization of cellulose. 196113690357
relation of temperature and sodium chloride concentration to growth and morphology of some halophilic bacteria. 196113705064
taxonomically significant color reactions of brevibacterium linens.grecz, nicholas (university of chicago, chicago, ill.), and gail m. dack. taxonomically significant color reactions of brevibacterium linens. j. bacteriol. 82:241-246. 1961.-brevibacterium linens was observed to give characteristic color reactions with certain bases and acids. an intensive carmine-red color appeared immediately after addition of a drop of 5 n sodium hydroxide, 5 n potassium hydroxide, and saturated barium hydroxide. a light carmine-red was given by lithium hydroxide, and a light ...196113708147
[the use of spectrochemistry for determination of the composition of bacteria]. 196113764833
metabolism of pyruvic and formic acids by zymosarcina ventriculi. 195913797599
metabolism of sarcina lutea. iv. patterns of oxidative assimilation. 196013800799
studies on sarcina ventriculi. i. stock culture method. 196013807366
studies on sarcina ventriculi. ii. nutrition. 196013807367
electron microscopy of cellular division in sarcina lutea. 196013809226
role of fatty acids in the growth stimulation of sarcina species by vitamin-free casein digests. 195913815775
bacterial dissimilation of l-fucose and l-rhamnose.eagon, r. g. (university of georgia, athens). bacterial dissimilation of l-fucose and l-rhamnose. j. bacteriol. 82:548-550. 1961.-of 33 microorganisms screened for the ability to utilize the methylpentoses, l-fucose and l-rhamnose, 18 species utilized one or both methylpentoses. the majority of the bacterial species capable of utilizing these methylpentoses did so by isomerization of the methylpentoses to the corresponding ketoses followed by phosphorylation of the ketoses. however, the existenc ...196113888945
oxidative activity of psychrophilic and mesophilic bacteria on saturated fatty acids.sultzer, barnet m. (michigan state university, east lansing). oxidative activity of psychrophilic and mesophilic bacteria on saturated fatty acids. j. bacteriol. 82:492-497. 1961.-comparisons were made of the capacity of representative psychrophilic pseudomonads and of the mesophilic serratia marcescens and sarcina flava to oxidize sodium salts of fatty acids at temperatures ranging from 7.5 to 40 c. conventional manometric techniques were employed to determine respiration of whole cells and of ...196113918352
[sensitivity of staphylococci, micrococci and sarcina to antibiotics]. 196213927178
development of lysozyme resistance in micrococcus lysodeikticus and sarcina lutea. 196213931014
antimicrobial substances from aspen tissue grown in vitro.isolated aspen tissue, when grown in vitro for 3 weeks on agar medium, yielded antimicrobial substances which produced inhibitory zones when the culture plates were inoculated with fusarium roseum, saccharomyces cervisiae, bacillus subtilis, bacillus cereus, penicillium, roqueforti, torula utilis, sarcina lutea, flavobacterium aquatile, pullularia pullulans, and staphylococcus aureus.196313933593
comparative study of lethal photosensitization of sarcina lutea by 8-methoxypsoralen and by toluidine blue.mathews, micheline m. (department of bacteriology, university of california, berkeley). comparative study of lethal photosensitization of sarcina lutea by 8-methoxypsoralen and by toluidine blue. j. bacteriol. 85:322-328. 1963.-a comparative study has been made of the photo-killing of sarcina lutea by 8-methoxypsoralen (8-mop) and by toluidine blue. it has been found that photosensitization by 8-mop differs from photosensitization by toluidine blue, in that it has a temperature coefficient of le ...196313933608
[separation and testing of biologically active substances from mixtures of chloramphenicol and oxytetracycline]. 196313939402
the cytotoxic effects of hemolytic streptococci on ascites tumor cells. 196313961064
a classification of micrococci and staphylococci based on physiological and biochemical tests. 196313969076
biosynthesis of methane from the methyl moiety of methylcobalamin. 196313971581
[rapid method of differentiation of s and r forms of microorganisms according to their succinate dehydrogenase activity]. 196313972276
on the isolation of dipicolinic acid fromhendospores of sarcina ureae. 196313981202
production of l phase variants of bacteria with cycloserine. 196213998855
sedimentation characteristics of cytoplasmic particles from sarcina lutea. 196214016004
[on the antimicrobial action of the tissues of ctenophora beroe cucumis fabr]. 196214020551
laboratory studies on oxacillin. i. in vitro activity against staphylococci and some other bacterial pathogens. ii. absorption and urinary excretion in normal young men. 196314033374
free radical formation and survival of lyophilized microorganisms.heckly, robert j. (university of california, berkeley), r. l. dimmick, and j. j. windle. free radical formation and survival of lyophilized microorganisms. j. bacteriol. 85:961-966. 1963.-a correlation between death and spontaneous free radical production, measured by an increase in the relative electron paramagnetic resonance (epr) signal, was shown to exist for several species of microorganisms stored in the freezedried state, but the relationship between the free radical concentration and num ...196314044024
effects of carbon dioxide on the colonial growth of pathogenic leptospirae.yanagawa, r. (national institute of animal health, kodaira, tokyo, japan), t. hiramune, and j. fujita. effects of carbon dioxide on the colonial growth of pathogenic leptospirae. j. bacteriol. 85:875-880. 1963.-the growth of colonies of pathogenic leptospirae was examined in air of various co(2) concentrations, ranging from air from which co(2) was absorbed to air with 20% co(2) added, and was compared with the growth of other microorganisms of the genera mycoplasma, brucella, vibrio, erysipelot ...196314044957
nafcillin. antibacterial action in vitro and absorption and excretion in normal young men. 196314046010
antimicrobial action of nitrogen-containing steroids.smith, rodney f. (university of maryland, baltimore), donald e. shay, and norman j. doorenbos. antimicrobial action of nitrogen-containing steroids. j. bacteriol. 85:1295-1299. 1963.-a new group of 16 synthetic nitrogen-containing steroids have been tested against a variety of microorganisms for antimicrobial properties. the gradient plate screening method, serial dilution, and dry weight techniques were used in the studies. the organisms tested consisted of 14 gram-negative bacteria, 10 gram-po ...196314047220
[bacteria and plant tissues in culture]. 196314048711
comparative aspects of alcohol formation. 196314053260
a molecular mechanism of mitomycin action: linking of complementary dna strands. 196314060656
preparation of optically active gamma- and delta-lactones by microbiological reduction of the corresponding keto acids.it was found, by means of simple screening methods, that several yeasts (saccharomyces and candida), molds (cladosporium), and bacteria (sarcina) are able to reduce keto acids to hydroxy acids, which are easily converted into lactones. chemical analysis showed that some of the microorganisms (saccharomyces and candida) produce dextrorotatory lactones and others (cladosporium and sarcina) produce levorotatory lactones. high yields of dextrorotatory (both gamma- and delta-lactones) were obtained b ...196314063778
influence of sodium hexametaphosphate on selected bacteria.sodium hexametaphosphate (hex), the solvent of calcium alginate wool used in swabbing inanimate surfaces was studied relative to its effect on various bacterial populations, both pure cultures and wild. it was found that bacteria in wild populations were greatly inhibited, and that a percentage reduction of count was directly related to concentration of hex. most gram-positive bacteria were prevented from growing on a medium containing 0.1% hex. this, or a higher concentration, occurred in the f ...196314063787
survey of the bacteriocines of enterococci.brock, thomas d. (indiana university, bloomington), barbara peacher, and deborah pierson. a survey of the bacteriocines of enterococci. j. bacteriol. 86:702-707. 1963.-a survey has been made of bacteriocine production by a wide variety of well-characterized strains of group d streptococci. on the basis of spectrums and sensitivity to chloroform, heat, and proteolytic enzymes, five distinct bacteriocines can be defined. type 1 is produced by all streptococcus zymogenes (s. faecalis var. zymogenes ...196314066464
[on the antibiotic action of natural coumarins. iv. on the mechanism of antibacterial action of ostruthin]. 196314067710
color mutants of sarcina lutea induced by cobalt-60 irradiation. 196214067916
the taxonomic significance of the oxidation of carbon compounds by different strains of micrococcus luteus. 196314068465
colony count from mid-stream voided urine specimens as a screening method for asymptomatic bacteriuria in males in the medical ward. 196314080539
micromorphology of dermatophilus congolensis.gordon, morris a. (division of laboratories and research, new york state department of health, albany), and mercedes r. edwards. micromorphology of dermatophilus congolensis. j. bacteriol. 86:1101-1115. 1963.-as seen in electron micrographs of thin sections, dermatophilus congolensis is a holocarpic actinomycete that fragments, after formation of septa in several planes, into sarcina-like packets and then into individual cocci. release of coccal forms from the filaments and packets is by dissolu ...196314080778
further pharmacology and chemotherapy of cloxacillin.in concentrations greatly in excess of therapeutic blood levels cloxacillin has a slight hypotensive action. as with other antibiotics, it sometimes causes diarrhoea in rabbits but, in doses up to 200 mg/kg, it does not have a teratogenic effect on the rabbit foetus. cloxacillin is distributed throughout the body. high concentrations are found only in the liver and kidney, these reflecting the high concentrations in the bile and urine respectively. it differs from other penicillins investigated ...196314081664
[contribution to the study of the richness of the marine environment in antibiotic-producing bacteria]. 196314090557
[on a combination of theophylline and phenylmercuric hydroxide]. 196314097840
a common antigen in the cell walls of three lysozyme-sensitive bacteria. 196314101607
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