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observations on environmental contamination in a microbiological laboratory.contamination of a laboratory environment with pathogenic or non-pathogenic micro-organisms may be relevant to safety of technicians and quality of technical performance. two widely separated incidents in 1968 and 1974 initiated a study of aspects of the laboratory environment. water-baths, water of syneresis and portions of salmonella cultures spurting out of the sterilizing flame were examined. the water of water-baths was shown to be contaminated from the fluid cultures incubated in them. thi ...19761107415
[antimicrobial and antineoplastic properties of alkaloids of greater celandine and their thiophosphamide derivatives]. 19751107767
[an analysis of meat products as possible factors responsible for transmission of dysenterial toxic infections].the paper carries experimental data derived from a bacteriological analysis of infected minced meat products for the presence of shigella sonnei and for ascertaining technological stages non-compliance with whose proper course presents the greatest epidemiological hazards. the procedures employed in analyzing infected meat products are shown to be sufficiently sensitive, for they enable one to count shigella dysenteriae in numbers of 102-106/g, depending upon the degree of total bacterial contam ...19751108439
[adjuvant action of nonspecific inflammation in immunizing guinea pigs vis the keratoconjunctival sac with shigella sonnei somatic antigens]. 19751108517
[biological characteristics of biochemical variants of sh. sonnei]. 19751108532
[shigella in seawater and in an estuary. iii. determination in vitro of the survival time of s. sonnei ycd in seawater]. 19751108731
[prodigiosin in the overall therapy of dysentery and in the prevention of intrahospital viral respiratory infection in children].prodigiozan was tested in complex therapy of children with acute dysentery. comparison of clinical symptoms, specific immunogenesis and child sanation periods from shigella in the child groups treated (80) and non-treated (74) with prodigiozan showed that prodigiozan lowered the rate of intrahospital acute respiratory virus infection, provided more favourable dysentery progression, more tensed specific immunity and the patient clearance from shigella.19751108774
[potassium distribution and glycogen metabolism under muscle load in rats. ii. changes in muscle and liver lactate, glycogen and water]. 19751116029
relative intelligibility of the cid spondees as presented via monitored live voice.using three speakers and 75 subjects, a 7.90db range in the relative intelligibility of the central institute for the deaf (cid) spondees was found when they were presented via monitored live voice. this range is consistent with previous research and is considered unnecessarily large and detrimental to the efficiency and precision of the speech reception threshold (srt) test. the exclusive use of 18 words that have a mean range of 1.5 db is suggested. the slope of the 3l-item spondee articulatio ...20021123931
the measurement of iron-binding capacity in serum and purified transferrin with the aid of chemical affinity chromatography.in a mew method for the estimation of transferrin by iron-binding capacity iron is added as the tartrate in nacl with about 10 mm bicarbonate. the excess iron is removed by passage through deae-sephadex a-50 previously treated with the iron chelator disodium catechol-3,5-disulphonate. the iron remaining bound to transferrin is measured without protein precipitation by the use of ferrozine. the method is applicable to fresh, frozen, or lyophilized serum, purified transferrin, and some quality con ...20051127111
an intergrative factor analysis of leadership measures and theories.since the instruments for measuring most of the current leadership models have never been reconciled, it is important that the relationships between them be clearly understood before assumptions of similarity are made. a sample of 103 male working students were given a battery of tests measuring leadership orientations. the tests included role preference and role pressure measures from sweney's response to power model, the california f scale, fiedler's least preferred co-worker scale and assumed ...20051151904
tunnel ulcer with double pyloric canal.double pyloric canal produces a recognizable roentgen pattern. a split barium column at the pyloric canal results in an interposed pseudo-defect which must not be confused with tumor mass. the condition is usually caused by a tunnel ulcer extending from the distal stomach to the duodenal bulb and is probably more common than the small number of reported cases would suggest.20051153732
compartmental evaluation of osteoarthritis of the knee. a comparative study of available diagnostic modalities.the distribution and severity of osteoarthritis were investigated in 56 knees by history and physical examination, assessment of knee function, radiography with and without weight-bearing, double-contrast arthrography, and 99mtc-polyphosphate bone imaging. compartmental involvement (medial, lateral, patellofemoral) was graded independently by 2 or 3 observers for each modality and was correlated with that observed during arthroscopy or direct surgical inspection. the more involved compartments w ...20051153764
antimicrobial resistance of shigella isolated in new york city in 1973.one hundred and two shigella sonnei and fourteen s. flexneri strains isolated from individual patients in new york city hospitals were investigated for antibiotic resistance. the s. sonnei showed 60% resistance to ampicillin and 58% to tetracycline and streptomycin. s. flexneri showed no ampicillin resistance but 50% resistance to tetracycline. there were marked differences in resistance of s. sonnei between hospitals which were not explainable by ethnic or socio-economic differences in the pati ...19751155925
time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats.previous neuroanatomical work has shown that lesions of the entorhinal cortex in adult rats cause the commissural projections to spread from their normally restricted locus in the inner molecular layer approximately 40-50 mum into the outer molecular layer (that is, into the zone deafferented by the lesion). in the present study we measured the effects of the entorhinal lesion on the distribution of short-latency potentials elicited by commissural stimulation in the molecular layer. studies with ...19751175043
glipizide - another oral hypoglycaemic drug. 20051183318
procainamide absorption studies to test the feasibility of using a sustained-release preparation.using in vitro techniques it was confirmed that whilst the release of procainamide from the conventional formulation (pronestyl) was rapid, that from the sustained-release preparation (cardiorytmin retard) occurred over a prolonged period. 2 the peak plasma procainamide concentrations after single doses of cardiorytmin retard were relatively lower and occurred later than those after single doses of pronestyl. furthermore, after reaching a peak, the fall in plasma procainamide concentration was l ...20051234015
management of pathological fractures at the mayo clinic. 20051234120
an acrylamide gel recombination assay for glycoprotein hormone subunits.a specific and sensitive assay for recombination of the subunits of hcg and other glycoprotein hormones (lh, fsh, and tsh) is presented. the assay depends on the ability of sodium dodecylsulfate polyacrylamide gel electrophoresis (sds-page) to separate clearly the subunits from native hormone. iodinated subunit is incubated with its identical unlabeled subunit and complementary subunit. quantitative displacement of the radioactivity to the native hormone position as followed by gel slicing is us ...20051248459
[diagnostic problems in gout in a 44-year-old man]. 19761251615
[hyperosmotic, hyperglycemic, non-ketotic diabetic coma]. 20051251624
editorial: who owns your medical records? 20051262726
[psychiatric side-effects of levodopa treatment]. 20051265908
antimicrobial susceptibilities of shigellae isolated in houston, texas, in 1974.one hundred seventy-three strains of shigellae (113 shigella sonnei, 56 s. flexneri, and four others) isolated in houston during 1974 were tested for susceptibility to commonly used and newer antimicrobial agents. forty-five percent of s. sonnei strains were susceptible to ampicillin, whereas 93% of s. flexneri strains were susceptible to that agent. s. sonnei and s. flexneri strains were equally susceptible to tetracycline (35 and 33%, respectively). all 173 strains were uniformly susceptible t ...19761267426
the effects of ethnicity of subject and accent and dependency of conferderate on aggressiveness and altruism. 19791271771
neonatal tetanus: a developmental follow-up study. 20051278947
[the effect of shigella sonnei strains opposite in their virulence on different links in the immune system].for the first time different action of s. sonnei strains, opposite in their virulence, on hematopoiesis and the functional activity of t- and b-lymphocytes has been shown. the hematopoiesis-disturbing action of virulent shigellae is manifested by their capacity, more pronounced than similar capacity of an avirulent (vaccine) strain, for stimulating the processes of endo- and exocolony formation, the proliferation of hematopoietic stem cells and their migration to the blood. the effect produced b ...19921279912
effect of natural and synthetic immunomodulators on the synthesis of interferon by peritoneal cells of mice.the effect of different natural and synthetic immunomodulators on the spontaneous interferon (ifn) synthesis by freshly isolated resident peritoneal cells of balb/c, nzb and c3h mice was investigated. actinomycetal glycolipids isolated from curtobacterium betae, faenia rectivirgula, rothia dentocariosa and saccharopolyspora hirsuta at the concentration 1-20 micrograms/ml were found to potentiate the ifn synthesis by the peritoneal cells of balb/c mice. similar results were obtained when dsrna, l ...19921279963
characterization of a lipopolysaccharide encoded by a recombinant shigella sonnei plasmid in escherichia coli k-12.the genetic information to synthesize the s-specific region of shigella sonnei phase i lipopolysaccharide (lps) is localized on a 180 kb plasmid which is lost quite readily. a recombinant plasmid derivative remaining stable in the bacteria was shown to determine the s-specific region of the lps which is completely identical with that of a s. sonnei phase i strain following transfer in escherichia coli k-12. however, the length control in polysaccharide biosynthesis is lost at least partially.19921284653
dysentery due to shigella infection. 19921285156
an outbreak of foodborne shigella sonnei infection. 19921285187
[the intoxication syndrome in acute dysentery]. 19921293830
[the effect of short-term adaptation to high-altitude conditions on human blood serum lipoproteins]. 19921307051
in vitro repair of double-strand breaks accompanied by recombination in bacteriophage t7 dna.a double-strand break in a bacteriophage t7 genome significantly reduced the ability of that dna to produce viable phage when the dna was incubated in an in vitro dna replication and packaging system. when a homologous piece of t7 dna (either a restriction fragment or t7 dna cloned into a plasmid) that was by itself unable to form a complete phage was included in the reaction, the break was repaired to the extent that many more viable phage were produced. moreover, repair could be completed even ...19921309515
effects of professional and media warnings about the association between aspirin use in children and reye's syndrome.the media played a central role in changing the use of aspirin among children with viral illness following reports of its association with a rare but deadly disease, reye's syndrome (rs). it did so by alerting health professionals and parents about ways to prevent rs in children. indeed, by the time aspirin product labeling was required by the fda in 1986, most of the decline in rs incidence had already occurred. in the past, media-only health education campaigns have been relatively unsuccessfu ...20051316991
optimal stimulation of paralyzed muscle after human spinal cord injury.muscle properties change profoundly as a result of disuse after spinal cord injury. to study the extent to which these changes can be reversed by electrical stimulation, tibialis anterior muscles in complete spinal cord-injured subjects were stimulated for progressively longer times (15 min, 45 min, 2 h, and 8 h/day) in 6-wk intervals. an index of muscle endurance to repetitive stimulation doubled (from 0.4 to 0.8), contraction and half-relaxation times increased markedly (from 70 to approximate ...19921317372
osmy, a new hyperosmotically inducible gene, encodes a periplasmic protein in escherichia coli.a new osmotically inducible gene in escherichia coli, osmy, was induced 8- to 10-fold by hyperosmotic stress and 2- to 3-fold by growth in complex medium. the osmy gene product is a periplasmic protein which migrates with an apparent molecular mass of 22 kda on sodium dodecyl sulfate-polyacrylamide gels. a genetic fusion to osmy was mapped to 99.3 min on the e. coli chromosome. the gene was cloned and sequenced, and an open reading frame was identified. the open reading frame encoded a precursor ...19921317380
inhibition site of dexamethasone on extravasation of polymorphonuclear leukocytes in the hamster cheek pouch microcirculation.a video system was used to investigate the inhibitory effect(s) of the glucocorticoid dexamethasone (dex) on polymorphonuclear leukocyte (pmn) extravasation in the microcirculation of hamster cheek pouch. dex was given intraperitoneally at 0.1 or 0.3 mg/kg body weight 2 h before induction of extravasation by topical application of leukotriene b4 (ltb4) or formyl-methionyl-leucyl-phenylalanine (fmlp) on the microvasculature. the number, time course, and behavior of pmns were examined in the follo ...20061326021
[shigellosis in children of the ix region of chile: clinical and epidemiologic aspects and antibiotic sensitivity].ninety four children with diarrhea and a positive stool culture for shigella, hospitalized at the hospital regional de temuco, were studied. forty six percent of patients were less than two years old. forty two percent of microorganisms were resistant to ampicillin, 45% to trimethoprim/sulfamethoxazole, 8% to tetracycline and none to chloramphenicol. isolated species were shigella flexneri 83% and shigella sonnei 17%. seventy nine percent of patients had fever, 60% dysentery and 21.3% seizures. ...19921340946
[the evaluation of transabdominal pelvic fluid collections. clinical cases].two cases of pelvic collections of different etiology, admitted in the isolation unit of the gynecology and obstetrics department of hospital del salvador are presented. both were resolved by means of ultrasound transabdominal puncture, the first a tubo-ovarian abscess, in which there was placed a percutaneous drainage, and the second, a residual lutein cyst, (subsequent' to an ectopic pregnancy resolved by surgery) by means only of punction. in the first case (tubo-ovarian abscess) the patient ...19941342424
[bacteriology of shigella isolated in a tropical zone chu].from 1981 to 1991, five hundred eighty one shigella's strains were isolated in the laboratories of the chu fann of dakar. they represent 24.8 per cent of enteropathogen agents and 4.3 per cent of diarrhoeae causative agents. shigella flexneri was predominant (71%), following by shigella dysenteriae (14.5%), shigella sonnei (11.4%) and shigella boydii (2.5%). in pediatric hospital 90 per cent of strains were isolated between 1 and 5 years age; in adults, the pic was found from 20 to 30 years. fiv ...19921345084
inhibitory effect of circulating insulin on glucagon secretion during hypoglycemia in type i diabetic patients.to clarify whether the circulating insulin level influences hormonal responses, glucagon secretion in particular, during hypoglycemia in patients with insulin-dependent (type i) diabetes.20061346593
sexual transmission of htlv infections in southern india. 19921346809
[endoscopic ultrasonographic study of gastric ulcer treated with proton pump inhibitor].we examined 70 cases of gastric ulcer by endoscopic ultrasonography. of these, 18 cases were treated with proton pump inhibitor (ppi), another cases were treated with histamine h2 receptor antagonist or mucosal protective drugs. the endoscopic cumulative healing rate at the eighth week was 71.4% in all gastric ulcers. on the other hand, all of gastric ulcers treated with ppi were healed within eight weeks endoscopically. gastric ulcers which were revealed ultrasonographically to be refractory wi ...20061347334
molecular epidemiology of shigella infections in israel.the dnas of shigella sonnei or shigella dysenteriae type 1 strains isolated in outbreaks of shigellosis or in sporadic cases were analysed by restriction fragment length polymorphism (rflp). southern blots of the dnas of 36 s. sonnei isolates digested by 8 restriction enzymes were hybridized with an escherichia coli rrna probe. the s. sonnei strains were unexpectedly diverse in their rflp. antibiotypes of the same isolates showed clusters of strains corresponding to the various outbreaks. on the ...19921356821
beta adrenergic receptor desensitisation may serve a cardioprotective role.the aim was to test the hypothesis that beta adrenoceptor desensitisation is a form of cardioprotection whereby the myocardium is protected from the injurious effects of excessive adrenergic stimulation by isoprenaline.19921360332
pyrizinostatin: a new inhibitor of pyroglutamyl peptidase. 19921361487
[lipid and mineral metabolism and morbidity with temporary loss of work capacity in miners].examination is performed on 87 miners from mine for copper production subject to intensive local vibrations with average rate of increase (k) of the norms for the individual octave frequencies 2.4 times for 3 h exposure of the working shift, as well as to intensive noise--113-115 db/a equivalent level, general dust--23 mg/m3, fine dust--3.5 mg/m3 and fine quartz--0.43 mg/m3. there are data for vibration effect--changes in the cold test, vibration sensoriness, ultra sound sonometry, in all miners ...20051364539
separation processes in biotechnology. ion-exchange processes.through the use of several differentiating mechanisms, ion exchangers can separate ionic and nonionic materials, solutions containing only ionic species, and even completely nonionic mixtures. although the mechanisms are distinct in their mode of operation, the resin characteristics that influence the results are largely the same. a practical understanding of the resin properties involved is all that is necessary to begin to use ion-exchange resins successfully. ion exchange owes most of its his ...20061366881
immunochemical characterization of citrobacter strain pcm 1487 o-specific polysaccharide- and core oligosaccharide-protein conjugates.o-specific-polysaccharide and core oligosaccharide were isolated from citrobacter strain pcm 1487 lipopolysaccharide and purified. the polysaccharide was selectively devoid of 4-deoxy-d-arabinohexose residues. covalent conjugates of the modified o-specific polysaccharide and of the core oligosaccharide with tetanus toxoid were prepared. immunochemical characterization of these conjugates proved that they are strong immunogens. using monospecific rabbit antisera raised against the conjugates, the ...19921376131
health checks on patients 75 years and over in nottinghamshire after the new gp contract.to investigate annual health checks for patients of 75 years and over required by the 1990 contract for general practitioners.20061393076
monitoring of antibiotic resistance in shigellae isolated in the netherlands 1984-1989.during surveillance of antimicrobial resistance in shigella strains isolated in the netherlands from 1984 to 1989 and forwarded to the national institute of public health and environmental protection for typing, sensitivity to twelve antimicrobial agents was assessed. high rates of resistance to the older drugs of choice in treating shigellosis were found, i.e. ampicillin and trimethoprim-sulfamethoxazole. ampicillin resistance varied from 33 to 53% among shigella flexneri strains and from 10 to ...19921396730
[plasmid analysis and antibiotic resistance pattern measurement of shigella in chengdu].a total of 81 strains of shigella isolated from sporadic cases and cases in an outbreak of shigella sonnei infection was analysed by plasmid profiles and antibiotic resistance patterns. the strains had a high resistance patterns. the strains had a high resistance of ampicillin, tetracycline, trimethoprim-sulfamethoxazole and chloramphenicol; while 97.2% of the strains were susceptible to gentamicin, kanamycin. the results showed that 50% of the strains harbored plasmid patterns within each speci ...19921398620
an analysis of the quantitative relationship between oral temperature and severity of illness in experimental shigellosis.the relationship between oral temperature and other parameters of illness was examined in 139 adult volunteers infected experimentally with shigella sonnei. in subjects developing clinical disease, peak temperature correlated positively with total number of signs and symptoms other than fever (rxy = .71, p < .001), stool volume (rxy = .41, p < .001) and number of stools produced during the illness (rxy = .46, p < .001). peak temperature correlated negatively with incubation period (rxy = -.34, p ...19921402032
an international foodborne outbreak of shigellosis associated with a commercial airline.to determine the source of an international outbreak of shigellosis associated with consumption of food served by a minnesota-based airline.19921433760
[the characteristics of cryptosporidiosis prevalence in nizhni novgorod province].a total of 4070 patients with acute intestinal diseases were tested for cryptosporidiosis in 1989, 1806 of these without diarrhea (controls), 286 of them working at slaughter houses, milk-packing plants and dairy plants, 192 subjects with a history of contacts with cryptosporidiosis patients in the focus of the disease, and 7 animals. cryptosporidiosis was responsible for 3.2% of acute intestinal conditions in children; cryptosporidia oocysts were not detected in adults or healthy subjects. the ...19921435583
[lipopolysaccharide changes in smooth-type avirulent shigella in comparison with initial virulent strains].the comparative study of the lipopolysaccharides (lps) of virulent and avirulent strains of s. sonnei, phase i (smooth colonies), has been made. electrophoresis of lps and subsequent densitometry of electrophoregrams have revealed the increase of the fraction of long 0-chains with a considerable number of recurring elements in 2 out of 3 lps preparations obtained from avirulent shigellae. in mice immunized with these lps preparations a considerably greater number of antibody-producing cells can ...19921441805
activities of newer fluoroquinolones against shigella sonnei.the activities of six fluoroquinolones were determined for 117 separate strains of shigella sonnei. the order of increasing activity (mics for 90% of strains tested) was enoxacin (0.25 micrograms/ml), temafloxacin (0.032 micrograms/ml), sparfloxacin (0.016 micrograms/ml), ci-960 (0.008 micrograms/ml), ciprofloxacin (0.008 micrograms/ml), and pd-131628-2 (0.008 micrograms/ml). these data, along with results of killing and mutational rate studies, showed that all six fluoroquinolones were highly i ...19921444317
synthesis and antiplatelet activities of n-arylmethyl-3,4-dimethylpyrano[2,3-c]pyrazol-6-one derivatives.a series of new 1- and 2-arylmethyl-3,4-dimethylpyrano[2,3-c]pyrazol-6-one derivatives were synthesized and examined for their antiplatelet activities. some of these compounds showed significant inhibitory activities. among them, 1-phenylmethyl-3,4-dimethylpyrano[2,3-c]pyrazol-6(1h)-one (4a), 2-(2'-methoxyphenyl)methyl-3,4-dimethylpyrano[2,3-c]pyrazol-6(2h)- one (3e) and 2-(3'-methoxyphenyl)methyl-3,4-dimethylpyrano[2,3-c]pyrazol-6-(2h) - one (3f) were the most effective. these inhibitors acted ...19921446375
"raynaud's disease" in migraineurs: one entity or two?two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ...20061446993
inhibition of shigella sonnei by lactobacillus casei and lact. acidophilus.the protective effect of feeding milk fermented with a mixture of lactobacillus casei and lact. acidophilus against shigella sonnei was studied. there was a 100% survival rate in mice fed for 8 d with fermented milk and then dosed orally with sh. sonnei. the survival rate in control mice was approximately 60% after 21 d. colonization of the liver and spleen with sh. sonnei was markedly inhibited by pretreatment with fermented milk. differences in cell counts of 2-3 log units between treated and ...19921447056
concentration of milk secretory immunoglobulin a against shigella virulence plasmid-associated antigens as a predictor of symptom status in shigella-infected breast-fed infants.we conducted a prospective, community-based study of healthy breast-fed mexican infants to determine the protective effects of anti-shigella secretory iga antibodies in milk. milk samples were collected monthly, and stool culture specimens were obtained weekly and at the time of episodes of diarrhea. nineteen breast-fed infants were found to have shigella flexneri, shigella boydii, or shigella sonnei in stool samples. ages of the 10 infants with symptomatic infection and the nine with asymptomat ...19921447644
fine needle aspiration cytology of primary soft tissue tumors. morphologic analysis of the most frequent types.we reviewed 98 cases of fine needle aspiration of soft tissue tumors with histologic confirmation performed during an eight-year period and propose a working morphologic classification based on the most prominent cytologic features. six main tumor groups are recognized: myxoid, round cells, spindle cells, pleomorphic cells, polygonal cells and well differentiated. we believe that this classification allows recognition of the most common soft tissue tumors while helping with the differential diag ...20061449029
diaphragmatic movement using ultrasound during spontaneous and mechanical ventilation: effect of tidal volume.using ultrasound (us) the effect of various tidal volumes on the movement of ventral, dome and dorsal parts of the right hemidiaphragm was studied, both during spontaneous and mechanical ventilation. six healthy non-medicated volunteers who were in the supine position breathed spontaneously shallowly (tidal volume (vt) being 400 ml) (sb), and deeply (vt 1000 ml) (sb-deep). in addition, they were mechanically ventilated with intermittent positive pressure ventilation at three different vt's: 500 ...20061449048
haloperidol does not alter expression of ethanol-induced conditioned place preference.a recent experiment (risinger et al., psychopharmacology, 107 (1992) 453-456) has shown that haloperidol does not prevent acquisition of ethanol-induced conditioned place preference, suggesting that dopaminergic mechanisms do not mediate the primary rewarding properties of ethanol. the present experiment examined whether haloperidol would prevent the expression of conditioned reward to ethanol-paired stimuli using the place conditioning paradigm. dba/2j mice received four pairings of a tactile s ...20061449638
[the immunocorrective therapy of patients with acute dysentery]. 19921455821
[the excretion of shigella antigens in persons recovering from dysentery].shigella antigens can be detected in the excreta of convalescents after dysentery for a long time. most frequently these antigens occur in feces, less frequently in urine and rarely in saliva. according to indirect data, s. flexneri 1-6 antigens can be detected in excreta for a longer period after convalescence than s. sonnei antigens. when antigen indication is used for the diagnosis of dysentery and epidemiological analysis is carried out, one should bear in mind the length of the agent persis ...19921455962
[the etiological structure of shigellosis in the former ussr--an indicator of the activity of the main routes of infection transmission].the data on the etiological structure of shigella infections in the ussr in 1988-1989 are presented. the study showed the dominating role of s. flexneri with s. sonnei also retaining great importance in shigella infections. the process of the liquidation of s. dysenteriae and s. boydii infections began in some large cities. the domination of dysentery caused by s. flexneri and a high typhoid rate, particularly in central asia, were due to poor water supply of the population. the spread of dysent ...19921455964
reduction of indoor airborne mould spores.in 23 dwellings in copenhagen high concentrations of airborne mould spores were shown by the "open petri dish" method. the families were instructed how to reduce this contamination. one year later the number of mould spores was estimated again. at that time their number was 1/10 of that shown at the first sampling in 11 dwellings, and in 7 dwellings the reduction of mould spores decreased to 1/5. only one dwelling showed no reduction.20061456406
determining the variability of performance on wingate anaerobic tests in children aged 6-12 years.in two parts, this study investigated variability of performance in wingate anaerobic tests (wants) of normal, healthy, male children aged six, eight, ten and twelve years. the purpose of the first part of the study was to investigate the mean coefficient of variation (c.v. = [s.d./x].100) of children who performed four wants over a period of four weeks. the results revealed age-related differences in the performance data of peak power (pp) and mean power (mp) but no differences between age grou ...20061459745
protection from shigella sonnei infection by immunisation of rabbits with plesiomonas shigelloides (svc 01).plesiomonas shigelloides, an organism commonly found in water, is only rarely associated with diarrhoea in man. p. shigelloides serotype o:17 (svc o1), which is antigenically similar to shigella sonnei, was found to be neither virulent nor toxic for rabbits. rabbits immunised by feeding with p. shigelloides (svc o1) were completely protected against an oral challenge with 10(10) cells of s. sonnei but non-immunised rabbits were not. p. shigelloides (svc o1) may be a useful vaccine strain for shi ...19921460657
[diagnosis of acute diarrheal infections]. 19921460834
[the effect of a ribosomal shigella sonnei vaccine on cellular immune reactions].the influence of s. sonnei ribosomal vaccine on hematopoiesis, t- and b-cell-mediated immune reactions has been studied in the course of the development of experimental vaccinal process. the vaccine stimulated hematopoiesis, that was characterized by a dose-dependent increase in colony-forming units in the spleen (cfus), a rise in cfus in the blood and bone marrow and an increase in the pool of proliferating stem cells in bone marrow, shortly after injection. a pronounced immunostimulating effec ...19921466169
[the theoretical and practical interpretations of the basic manifestations of the epidemic process in shigellosis]. 19921466177
[the characteristics of the colonization resistance of the intestines in conventional animals with a history of clinical death].after modeling the terminal state caused by the acute loss of blood in rats their intestinal microflora was studied, as was their resistance to colonization. decreased resistance to colonization was registered early after resuscitation (up to 3 days), which was confirmed by the translocation of bacteria into internal organs, decreased number of lactobacilli in the contents of the small intestine and elevated level of enterobacteria in the intestine. disturbances in resistance to colonization was ...19921466180
[bacillary dysentery--1990]. 19921475396
ultrastructural alterations of brain cortex in rat following intraperitoneal administration of mercuric chloride.intraperitoneal administration of a single dose (6 mg/kg body weight) of mercuric chloride (hgcl2) results in ultrastructural changes in brain cortex of the rats. 18 hours after administration of hgcl2 the accumulation of dense deposits of mercury in nerve and glial cell cytoplasm was observed. the quantity of microglia in neuropil was also increased in this experimental group. we postulate that these cerebral macrophages can play an important role in the process of intoxication, too. 5 days aft ...19921479187
[multiyear observations of the dynamic epidemic process in sonne dysentery in a small district of vladimir province].on the basis of the epidemiological analysis of morbidity data for several years the many-sided dynamic characterization of the epidemic process of sonne dysentery in a small district is presented. as revealed by this analysis, the epidemic process developed in the presence of residual activity of the water factor; this activity was mediated by transmission of this infection through milk products contaminated in the course of their manufacture and distribution. the possibility of appearance of a ...19921481603
the integration of a continuous-speech-recognition system with the qmr diagnostic program.we describe a continuous-speech interface for quick medical reference (qmr), which allows physicians to input spoken descriptions of physical-examination findings, or observations. we analyze the difficulties in designing a continuous-speech interface for systems that use medical terminology. we present a method for matching spoken findings names expressed in natural language to qmr terms. the method is based on a semantic representation of findings that both minimize the effect of misrecognitio ...20061482975
chartline: providing bibliographic references relevant to patient charts using the umls metathesaurus knowledge sources.a successful medical informatics program helps its users to match their information needs as closely and efficiently as possible to the capabilities of the system. chartline is a computer program whose input is a free text, "natural language" patient chart in ascii format. using the umls metathesaurus knowledge sources, chartline can suggest bibliographic references relevant to the patient case described in the chart. the program does not attempt to "understand" the natural language content of t ...20061483014
[disasters in former east germany--experiences and problems of the leipzig "identification" task group].mass-disasters with high numbers of victims are a real challenge to the specialists. the role of forensic experts is generally emphasized. the missions of the leipzig taskgroup for identification and the experience gained during them confirm, that special training necessary staff members is. compared with the general signs of identity, like clothing, jewelry and accessories, scars etc., the marks of ears and observations of forensic odonto-stomatology provide good chances for identification. for ...20061489335
asbestos: the turbulent interface between science and policy. 20061489439
basaloid-squamous carcinoma. 20061489448
dna adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for dna adduct-based human cancer risk assessment. 19921489923
in vitro studies on the growth of shigella sonnei by lactobacillus casei and lact. acidophilus.the inhibitory effect of lactobacilli on growth of shigella sonnei was studied. the effect was not due to ph alone, as addition of hydrochloric, lactic or acetic acids to culture media did not inhibit the normal growth of the shigellas. the degree of inhibition was measured by disc assay and showed that the inhibitory substance(s) can be extracellular and diffusible, varying the degrees of inhibition depending on the media tested. when broth was inoculated with mixed cultures of lactobacillus an ...19921490909
[territorial differences in the nature of the etiological structure of shigellosis--a pattern or chance?]. 19921496882
presence of specific immunoglobulin a-secreting cells in peripheral blood after natural infection with shigella sonnei.the appearance of antigen-specific immunoglobulin a (iga) antibody-secreting cells (ascs) following natural infection with shigella sonnei during a common-source outbreak caused by this organism was evaluated in a modified enzyme-linked immunosorbent assay (elispot). a mean iga asc value of 2,131.6/10(6) cells against homologous s. sonnei lipopolysaccharide (lps) was detected in blood samples obtained from patients with bacteriologically proven s. sonnei shigellosis 5 and 10 days after the onset ...19921500527
[etiological structure of dysentery in the republic of armenia].in this work materials on the etiological structure of shigella infections at different territories of armenia are presented. four shigella species have been found to circulate in armenia. the dominating etiological agent is s. flexneri with s. sonnei also playing an important role. the serological picture of s. flexneri is characterized by the prevalence of subserovar 2a.19921509848
[the correspondence theory and etiological structure of shigella infections]. 19921509850
[sensitivity of shigella to antibiotics].three hundred and twenty two shigella cultures isolated from dysentery patients within 1986-1989 were tested with the use of standard paper disks for their sensitivity to levomycetin, streptomycin, tetracycline, monomycin, neomycin, kanamycin, erythromycin, gentamicin, carbenicillin, ampicillin, oxacillin, methicillin and doxycycline. the number of the cultures belonging to shigella sonnei amounted to 85.1 per cent of the total number of the strains studied. 91.9, 89.5, 87.3, 87.3, 80.1 and 80.1 ...19921514848
titres of class-specific antibodies against shigella and salmonella lipopolysaccharide antigens in colostrum and breast milk of costa rican, swedish and vietnamese mothers.enzyme immunoassays (eia) were used to estimate titres of class-specific antibodies against purified and chemically defined phenol-water-extracted lipopolysaccharide (lps) antigens of salmonella serogroup b (bo), shigella dysenteriae type i, plesiomonas shigelloides (the same o-antigen as shigella sonnei) and shigella flexneri y. titres in colostrum and breast milk of swedish, vietnamese and costa rican mothers from various socioeconomic conditions were compared. the antibodies were mainly of th ...19921522329
[clinical evaluation of a new carbapenem, meropenem, in infants and children].a new carbapenem antibiotic, meropenem (mepm), was evaluated for its safety and efficacy in 33 infants and children. mepm was effective in all the 32 evaluable cases including 4 cases of bacterial meningitis and 5 cases of pseudomonas aeruginosa infections. the mean half life of plasma concentrations of mepm was 0.84 +/- 0.09 hours after 30 minutes intravenous drip infusion. mild diarrhea (2 cases), transient elevation of transaminases (8 cases), and transient eosinophilia (2 cases) were associa ...19921522678
comments on practical implications of coexistent different technologies in clinical chemical laboratories. reply to the letter to the editor by m. hardel (this j. 30 (1992) 239-240) 20061525257
laboratory test form design influences test ordering by general practitioners in the netherlands.the effect of listing fewer laboratory tests on the test request form on test-ordering behavior of a group of 47 dutch general practitioners was studied. the number of laboratory tests ordered by this experimental group during a 12-month period was recorded. the usual, old standard form was used by a control group of 28 general practitioners in a different region. after having used the old, standard form with 178 tests for 5 months, the experimental group received forms listing only 15 hematolog ...20061538607
early detection of colorectal cancer. 20061538998
risk factors for suicide attempts in a human immunodeficiency virus screening program. 19921539099
congenital myotonic dystrophy and mtdna. 20061539603
drug resistance and plasmid profile of shigellae in taiwan.one hundred and twenty-eight shigella strains isolated from newborn and infant human faecal specimens at kaohsiung medical college hospital in taiwan were serogrouped, serotyped and examined for drug-resistance patterns and for the presence of plasmids. forty-seven per cent of the isolates were found to belong to the shigella sonnei serogroup, 41% to the s. flexneri group, 9% to the s. boydii group and 3% to the s. dysenteriae group. the serotype with the greatest number of strains was s. sonnei ...19921547844
pulsatile growth hormone secretion during the breeding season in male reindeer and its association with hypophagia and weight loss.male deer reduce food intake and lose weight during the breeding season (rut) in autumn. growth hormone (gh) is lipolytic in ruminants; therefore, pulsatile gh secretion was measured in three young reindeer (rangifer tarandus tarandus) bulls during the natural period of weight loss during rut. blood samples were withdrawn through a jugular cannula every 20 min for 16 hr on 5 occasions from late summer to early winter in unanaesthetised animals. the deer were group fed a pelleted concentrate rati ...19921563616
pharmacodynamics of pemoline in attention deficit disorder with hyperactivity.the onset, duration, and offset of pemoline action to improve cognitive performance is examined intensively in 25 prepubescent males suffering from attention-deficit disorder with hyperactivity (addh). the purpose was to characterize the pharmacodynamics of pemoline in addh patients through correlation of plasma pemoline concentration with psychometric measures of memory search efficiency and paired-associates learning, with the physiological effect of pemoline on dopaminergic transmission concu ...20061564025
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