Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| toxigenicity of treponema hyodysenteriae, another emerging enteropathogen. | 1982 | 27709524 | |
| an investigation into the etiological agents of swine dysentery in australian pig herds. | swine dysentery (sd) is a mucohemorrhagic colitis, classically seen in grower/finisher pigs and caused by infection with the anaerobic intestinal spirochete brachyspira hyodysenteriae. more recently, however, the newly described species brachyspira hampsonii and brachyspira suanatina have been identified as causing sd in north america and/or europe. furthermore, there have been occasions where strains of b. hyodysenteriae have been recovered from healthy pigs, including in multiplier herds with ... | 2016 | 27907102 |
| the in vitro effect of garden thyme (thymus vulgaris l.) extract on brachyspira hyodysenteriae. | filtrates of a water extract of commercially available garden thyme (thymus vulgaris l.) were used for studying its possible bactericidal effect on brachyspira hyodysenteriae, the causative agent of swine dysentery, by agar-diffusion technique. five of the six studied brachyspira strains have proven to be sensitive and one moderately sensitive in the in vitro tests. it was concluded that water extract of garden thyme possesses inhibitory effects against b. hyodysenteriae. in vivo experiments are ... | 2016 | 27929352 |
| mechanisms of antibacterial action of quinoxaline 1,4-di-n-oxides against clostridium perfringens and brachyspira hyodysenteriae. | quinoxaline 1,4-di-n-oxides (qdnos) are a class of bioreductive compounds, however, their antibacterial mechanisms are still unclarified. the aim of this study was to assess the ability of two representative qdno drugs, cyadox (cya) and olaquindox (ola), to produce reactive oxide species (ros) in gram-positive anaerobe clostridium perfringens cvcc1125 and gram-negative anaerobe brachyspira hyodysenteriae b204. in addition, the effects of qdnos on the integrity of bacterial cell walls and membran ... | 2016 | 28018297 |
| correction for mirajkar et al., complete genome sequence of brachyspira hyodysenteriae type strain b78 (atcc 27164). | 2017 | 28104652 | |
| a novel multiplex qpcr targeting 23s rdna for diagnosis of swine dysentery and porcine intestinal spirochaetosis. | a multiplex qpcr targeting a 128 bp region on the 23s rdna gene was developed for detection of brachyspira (b.) hyodysenteriae and b. pilosicoli, the agents of swine dysentery (sd) and porcine intestinal spirochaetosis (pis), together with a triplet of apathogenic brachyspira spp. (b. innocens, b. intermedia, b. murdochii) in porcine feces. the multiplex qpcr was evaluated against a duplex pcr (la et al., j clin microbiol 41:3372-5, 2003). | 2017 | 28173799 |
| artificially designed recombinant protein composed of multiple epitopes of foot-and-mouth disease virus as a vaccine candidate. | concerns regarding the safety of inactivated foot-and-mouth disease (fmd) vaccine have been raised since it is produced from cultured live fmd virus (fmdv). to overcome this issue, recombinant protein has been studied as an alternative vaccine. | 2017 | 28228147 |
| an update of brachyspira hyodysenteriae serotyping. | brachyspira (b.) hyodysenteriae the causative agent of swine dysentery (sd) has been divided into 9 serotypes on basis of its lipooligosaccharide (los). knowledge on circulating serotypes in europe, however, is rare. regarding that immunity to sd is serotype specific an update of b. hyodysenteriae serotyping was undertaken. a los band of 10 to 25kda was identified being appropriate for this purpose. isolates from germany, spain, denmark, usa and japan were characterized in the immunoblot by sera ... | 2017 | 28249175 |
| brachyspira hyodysenteriae infection regulates mucin glycosylation synthesis inducing an increased expression of core-2 o-glycans in porcine colon. | brachyspira hyodysenteriae causes swine dysentery (sd), leading to global financial losses to the pig industry. infection with this pathogen results in an increase in b. hyodysenteriae binding sites on mucins, along with increased colonic mucin secretion. we predict that b. hyodysenteriae modifies the glycosylation pattern of the porcine intestinal mucus layer to optimize its host niche. we characterized the swine colonic mucin o-glycome and identified the differences in glycosylation between b. ... | 2017 | 28301166 |
| characterization of brachyspira hyodysenteriae isolates from italy by multilocus sequence typing and multiple locus variable number tandem repeat analysis. | to evaluate and compare the capabilities of multilocus sequence typing (mlst) and multiple locus variable number tandem repeat analysis (mlva) techniques to characterize brachyspira hyodysenteriae isolates and to investigate the relationship between pleuromutilin resistance and genetic variability. | 2017 | 28510989 |
| brachyspira hyodysenteriae and b. pilosicoli proteins recognized by sera of challenged pigs. | the spirochetes brachyspira hyodysenteriae and b. pilosicoli are pig intestinal pathogens that are the causative agents of swine dysentery (sd) and porcine intestinal spirochaetosis (pis), respectively. although some inactivated bacterin and recombinant vaccines have been explored as prophylactic treatments against these species, no effective vaccine is yet available. immunoproteomics approaches hold the potential for the identification of new, suitable candidates for subunit vaccines against sd ... | 2017 | 28522991 |
| neutrophil elastase and il17 expressed in the pig colon during brachyspira hyodysenteriae infection synergistically with the pathogen induce increased mucus transport speed and production via mapk3. | brachyspira hyodysenteriae colonizes the pig colon resulting in mucoid hemorragic diarrhea and mucus layer changes. these changes are characterized by a disorganized mucus structure and a massive mucus induction with de novo expression of muc5ac and increased production of muc2. to investigate the mechanisms behind this altered mucin environment, we quantified the mrna levels of mucin pathway genes and factors from the immune system in the colon of infected and control pigs, revealing upregulati ... | 2017 | 28559407 |
| in vitro susceptibility of brachyspira hyodysenteriae to a commercial citrus fruit extract. | brachyspira hyodysenteriae is the main etiological agent of swine dysentery (sd). nowadays, treatment and control of sd is increasingly difficult due to the emergence of antimicrobial resistance together with the restrictions on the use of antibiotics in veterinary practice. the aim of this study was to evaluate, as an alternative in the control of this disease, the antimicrobial activity and the main mechanism of action of biocitro, a citrus extract commercialized as raw material and used as fe ... | 2017 | 28651094 |
| emergence of brachyspira species and strains: reinforcing the need for surveillance. | this short review discusses the increasing complexity that has developed around the understanding of brachyspira species that infect pigs, and their ability to cause disease. it describes the recognition of new weakly haemolytic brachyspira species, and the growing appreciation that brachyspira pilosicoli and some other weakly haemolytic species may be pathogenic in pigs. it discusses swine dysentery (sd) caused by the strongly haemolytic brachyspira hyodysenteriae, particularly the cyclical nat ... | 2015 | 28694985 |
| metabolic response of porcine colon explants to in vitro infection by brachyspira hyodysenteriae: a leap into disease pathophysiology. | swine dysentery caused by brachyspira hyodysenteriae is a production limiting disease in pig farming. currently antimicrobial therapy is the only treatment and control method available. | 2017 | 28706469 |
| presence and mechanisms of acquired antimicrobial resistance in belgian brachyspira hyodysenteriae isolates belonging to different clonal complexes. | swine dysentery (sd) is an economically important disease for which antimicrobial treatment still occupies an important place to control outbreaks. however, acquired antimicrobial resistance is increasingly observed in brachyspira hyodysenteriae. in this study, the minimal inhibitory concentrations (mic) of six antimicrobial compounds for 30 recent belgian b. hyodysenteriae isolates were determined using a broth microdilution method. in addition, relevant regions of the 16s rrna, 23s rrna and th ... | 2017 | 28757011 |
| a review of methods used for studying the molecular epidemiology of brachyspira hyodysenteriae. | brachyspira (b.) spp. are intestinal spirochaetes isolated from pigs, other mammals, birds and humans. in pigs, seven brachyspira spp. have been described, i.e. b. hyodysenteriae, b. pilosicoli, b. intermedia, b. murdochii, b. innocens, b. suanatina and b. hampsonii. brachyspira hyodysenteriae is especially relevant in pigs as it causes swine dysentery and hence considerable economic losses to the pig industry. furthermore, reduced susceptibility of b. hyodysenteriae to antimicrobials is of incr ... | 2017 | 28757022 |
| an optimized swine dysentery murine model to characterize shedding and clinical disease associated with "brachyspira hampsonii" infection. | the development of a mouse model as an in vivo pathogenicity screening tool for brachyspira spp. has advanced the study of these economically important pathogens in recent years. however, none of the murine models published to date have been used to characterize the clinical signs of disease in mice, instead focusing on pathology following oral inoculation with various brachyspira spp. the experiments described herein explore modifications of published models to characterize faecal consistency, ... | 2017 | 28830508 |