Publications

Synthesis and Antibacterial Activities of Novel 2,5-Diphenylindolo[2,3-e] Pyrazolo[1',5':3",4"]pyrimido[2",1"-c] [1,2,4]triazines.	The formation of (E)-3-{2-(2,5-diphenylpyrazolo[1,5-c]pyrimidin-7-yl)hydrazono}indolin-2-ones 3 has been achieved by condensation of equimolar amounts of 7-hydrazino-2,5-diphenylpyrazolo[1,5-c]pyrimidine (1) and isatin (or isatin derivatives) 2 at room temperature. The (E)-products could be isomerized into corresponding the (Z)-3 isomers. Reactions of the latter fused heterocyclic hydrazones towards different electro-philic reagents yielded the corresponding 3-substituted derivatives 4-7. Dehydr ...	2011	22173333
functional analysis of two lebocin-related proteins from manduca sexta.	insects produce a group of antimicrobial peptides (amps) in response to microbial infections. most amps are synthesized as inactive precursors/pro-proteins and require proteolytic processing to generate small active peptides. here we report identification and functional analysis of two lebocin-related proteins (leb-b and leb-c) from the tobacco hornworm, manduca sexta. the mrna levels of leb-b and leb-c increased significantly in larval fat body and hemocytes after injection of escherichia coli, ...	2011	22198332
catalase-positive cocci in fermented sausage: variability due to different pork breeds, breeding systems and sausage production technology.	the aim of this study was to compare the ecology of catalase-positive cocci (cpc) present in traditional fermented sausages produced using different breeds of pork, each of which was raised in two different environments and processed using two different technologies. semi-quantitative molecular methods were used to determine bacterial identities. almost all fermentations were characterised by a significant increase in cpc during the first few days of fermentation, reaching values of 10(5)-10(6) ...	2012	22202871
The effects of different levels of orange fiber and fat on microbiological, physical, chemical and sensorial properties of sucuk.	The effects of orange fiber and fat levels on the physical, chemical and microbiological properties of sucuk (Turkish dry-fermented sausage) were investigated. Different levels of orange fiber (0, 2 and 4%) were added to sucuk batters with different levels of fat (10, 15 and 20%). Sucuk samples were analyzed during ripening. Lactic acid bacteria, Micrococcus/Staphylococcus and pH value were effected very significantly by orange fiber. Orange fiber caused a decrease in residual nitrite levels and ...	2012	22202881
Effect of polymorphism in egg white lysozyme on muramidase and antibacterial activities as well as hatchability in the Japanese quail (Coturnix japonica).	Lysozyme is one of the best characterized antimicrobial proteins in egg white. Three phenotypes of egg white lysozyme in Japanese quail, Coturnix japonica, (namely F, FS, and S) were observed by acid polyacrylamide gel electrophoresis. The fast (F) phenotype showed faster mobility on Acid-PAGE than the slow (S) phenotype. Comparison of the coding sequences for lysozyme derived from the S and F phenotypes revealed a nonsynonymous single nucleotide polymorphism (SNP) at nucleotide position 115 fro ...	2011	22205671
in vitro interaction of chronic wound bacteria in biofilms.	to use in vitro biofilm models of wound bacterial isolates and compare the biofilms produced for different combinations of wound bacterial species.	2011	22240883
identification and characterization of a serine protease inhibitor (ptserpin) in the swimming crab portunus trituberculatus.	serine protease inhibitors (serpins) play a key role in diverse immune biological processes. a serine protease inhibitor (serpin), namely ptserpin, was identified from the haemocyte cdna library of swimming crab portunus trituberculatus. the full-length ptserpin cdna was 1593 bp, including an open reading frame (orf) of 1227 bp encoding a polypeptide of 408 amino acids with estimated molecular mass of 45.048 kda and theoretical isoelectric point of 7.23. predicted tertiary structure of ptserpin ...	2012	22245590
synthesis and anti-microbial screening of novel schiff bases of 3-amino-2-methyl quinazolin 4-(3h)-one.	in the present study, novel schiff bases were synthesized by condensation of 3-amino-2-methyl quinazolin-4-(3h)-ones with different aromatic aldehydes. the 3-amino-2-methyl quinazolin-4-(3h)-one was synthesized from anthranilic acid via the 2-methyl benzoxazin-4-one. the chemical structures of the synthesized compounds were confirmed by means of infrared (ir), (1)h-nmr, (13)c-nmr, mass spectral, and elemental analysis. these compounds were screened for anti-bacterial (staphylococcus aureus atcc ...	2010	22247864
jbir-78 and jbir-95: phenylacetylated peptides isolated from kibdelosporangium sp. ak-aa56.	the search for metabolites of kibdelosporangium sp. ak-aa56 resulted in the discovery of novel n-phenylacetylated peptides, jbir-78 (1) and jbir-95 (2). compounds 1 and 2 were established to be n-phenylacetylated heptapeptides by extensive nmr and hresims analyses. the absolute configuration of the standard amino acids including a cysteic acid moiety was determined using marfey's method on the acid hydrolysates of 1 and 2. the relative and absolute configurations of a nonstandard amino acid, β-h ...	2012	22264203